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Petrusca Daniela N DN 1 Department of Medicine, Division of Pulmonary, Allergy, Critical Care, and Occupational Medicine, Indiana University School of Medicine, Indianapolis, - - 2014
Prolonged exposure to cigarette smoking is the main risk factor for emphysema, a component of chronic obstructive pulmonary diseases (COPDs) characterized by destruction of alveolar walls. Moreover, smoking is associated with pulmonary artery remodeling and pulmonary hypertension, even in the absence of COPD, through as yet unexplained mechanisms. In murine ...
Cappella Elise E Department of Applied Psychology, New York University, 246 Greene Street, New York, NY, 10003, USA, - - 2013
Applying social capital and systems theories of social processes, we examine the role of the classroom peer context in the behavioral engagement of low-income students (N = 80) in urban elementary school classrooms (N = 22). Systematic child observations were conducted to assess behavioral engagement among second to fifth graders ...
Göröcs Zoltán Z Electrical Engineering Department, University of California, Los Angeles, CA 90095, USA. - - 2013
We demonstrate a new fluorescent imaging technique that can screen for fluorescent micro-objects over an ultra-wide field-of-view (FOV) of ~532 cm(2), i.e., 19 cm × 28 cm, reaching a space-bandwidth product of more than 2 billion. For achieving such a large FOV, we modified the hardware and software of a ...
Rudolph Anja A Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 581, D-69120 Heidelberg, Germany PMV Research Group at the Department of Child and Adolescent Psychiatry and Psychotherapy, University of Cologne, Cologne, Germany Program in Molecular and Genetic Epidemiology, Harvard School of Public Health, Boston, Massachusetts, USA Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts, USA Foundation for Quality and Efficiency in Health Care (IQWIG), Cologne, Germany Human Genetics, Genome Institute of Singapore, Singapore, Singapore Department of Public Health and Primary Care, Centre for Cancer Genetic Epidemiology, University of Cambridge, Cambridge, UK INSERM (National Institute of Health and Medical Research), CESP (Center for Research in Epidemiology and Population Health), U1018, Environmental Epidemiology of Cancer, Villejuif, France Unité Mixte de Recherche Scientifique (UMRS) 1018, University Paris-Sud, Villejuif, France Institute for Prevention and Occupational Medicine of the German Social Accident Insurance, Institute of the Ruhr-Universität Bochum (IPA), Bochum, Germany Institute for Occupational Medicine and Maritime Medicine, University Medical Center, Hamburg-Eppendorf, Hamburg, Germany Department of Internal Medicine, Evangelische Kliniken Bonn gGmbH, Johanniter Krankenhaus, Bonn, Germany Institute of Pathology, University of Bonn, Bonn, Germany Molecular Genetics of Breast Cancer, German Cancer Research Center (DKFZ), Heidelberg, Germany Dr Margarete Fischer-Bosch-Institute of Clinical Pharmacology, University of Tübingen, Stuttgart, Germany Cancer Epidemiology Centre, The Cancer Council Victoria, Melbourne, Victoria, Australia Centre for Molecular, Environmental, Genetic, and Analytic Epidemiology, The University of Melbourne, Melbourne, Victoria, Australia Department of Pathology, The University of Melbourne, Melbourne, Victoria, Australia Division of Cancer Epidemiology and Genetics, - - 2013
Women using menopausal hormone therapy (MHT) are at increased risk of developing breast cancer (BC). To detect genetic modifiers of the association between current use of MHT and BC risk, we conducted a meta-analysis of four genome-wide case-only studies followed by replication in 11 case-control studies. We used a case-only ...
Birkhäuser Martin - - 2013
Abstract Protestantism is not a centralized religion. It is composed by many independent Churches having different moral and ethical standards. This review concentrates on the ethical principles prevalent in most modern European Reformed Churches. It does not intend to discuss the ethical principles of many other Protestant Churches present mainly ...
Dell'osso Bernardo - - 2013
Bipolar depression represents the most difficult-to-treat phase of bipolar disorder, mood-stabilizing compounds and second-generation antipsychotics being only partially effective, whereas the use of antidepressants is highly controversial because of risks of inefficacy, switching, rapid cycling, and increased suicidality. Among various augmentative pharmacological treatments, compounds with dopamine-enhancing activity have been shown ...
Pond Gregory J - - 2013
Stream bioassessments rely on taxonomic composition at sites compared with natural, reference conditions. We developed and tested an observed/expected (O/E) predictive model of taxonomic completeness and an index of compositional dissimilarity (BC index) for Central Appalachian streams using combined macroinvertebrate datasets from riffle habitats in West Virginia (WV) and Kentucky ...
Floreani Annarosa - - 2013
Cholangiocarcinoma (CCA) and gallbladder cancer are the second cause of liver malignancy after hepatocellular carcinoma. Epidemiological data point to an increase in the incidence of CCA in both western and eastern countries; however, data on more recent years are lacking. The aim of this study was to elucidate the more ...
Pullens Hendrikus J M - - 2013
Patients with an increased risk of having colorectal cancer (CRC) should have priority on the colonoscopy list. To investigate whether presenting symptoms of patients referred for colonoscopy could help in identifying patients with an increased risk of CRC. Between February 2007 and November 2010, random outpatients referred for colonoscopy were ...
Rets Anton - - 2013
Clinical presentation of strongyloidiasis in humans is highly variable, ranging from clinically inapparent infection to life-threatening multisystem disease. The course of infection is dependent on the immune status of the patient. Our objective was to ascertain the clinical characteristics of patients who developed reactivated strongyloidiasis from a primary infection acquired ...
Gase Lauren N - - 2013
Policies affecting the determinants of health lie largely outside the control of the health care and public health sectors. Ensuring health considerations in the formation and implementation of policies, programs, projects, and plans from all sectors, though lofty, is the overall aim of Health in All Policies. The purpose of ...
West Stephanie T - - 2013
Understanding barriers and facilitators to strategies directed at obesity-prevention policy change, particularly in rural, southern US counties where obesity is more prevalent, is important so that strategies deemed most winnable can be pursued. As such, community stakeholders and policy makers were interviewed using the Centers for Disease Control and Prevention's ...
Del Pup Lino - - 2013
Urogenital symptoms resulting from estrogen deficiency are common problems that impair quality of life and sexuality. Potentially, one out of three postmenopausal women could benefit from a vaginal estrogen therapy, but the fear of systemic absorption limits its use. Promestriene used vaginally to relieve vaginal atrophy is a locally effective ...
Liu Congyun - - 2013
A residue analytical method to detect pyrimethanil in tomatoes and soil was developed by using high-performance liquid chromatography with a diode array detector. The dissipation and residue level of pyrimethanil in tomatoes and soil were also investigated. Results showed that the average recoveries are in the range of 87.2 to ...
Sengupta Shaon S Division of Neonatology, Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, - - 2013
Full-term neonates born between 37 and 41 weeks' gestational age have been considered a homogeneous, low-risk group. However, recent evidence from studies based on mode of delivery has pointed toward increased morbidity associated with early-term cesarean section births (37-38 weeks) compared with term neonates (39-41 weeks). To compare the short-term ...
Wood Elisabeth M EM Department of Pathology and Laboratory Medicine, Center for Neurodegenerative Disease Research, Perelman School of Medicine at the University of Pennsylvania, - - 2013
A significant portion of frontotemporal lobar degeneration (FTLD) is due to inherited gene mutations, and we are unaware of a large sequential series that includes a recently discovered inherited cause of FTLD. There is also great need to develop clinical tools and approaches that will assist clinicians in the identification ...
Colson Eve R ER Department of Pediatrics, Yale University School of Medicine, New Haven, - - 2013
A strong association between infant bed sharing and sudden infant death syndrome or unintentional sleep-related death in infants has been established. Occurrences of unintentional sleep-related deaths among infants appear to be increasing. To determine the trends and factors associated with infant bed sharing from 1993 through 2010, including the association ...
Turko Nir A - - 2013
We present a method for adding molecular specificity to wide-field interferometric phase microscopy (IPM) by recording the phase signatures of gold nanoparticles (AuNPs) labeling targets of interest in biological cells. The AuNPs are excited by time-modulated light at a wavelength corresponding to their absorption spectral peak, evoking a photothermal (PT) ...
Caio Giacomo G aDepartment of Medical and Surgical Sciences/Digestive Diseases and Internal Medicine, St. Orsola-Malpighi Hospital bDepartment of Medical and Veterinary Sciences, University of Bologna, Bologna cDepartment of Internal Medicine, Division of Cardiology, San Giovanni Battista Hospital, University of Turin, Turin, Italy dEnteric NeuroScience Program, Division of Gastroenterology and Hepatology, Mayo Clinic College of Medicine, Rochester, Minnesota, - - 2013
A 26-year-old patient was diagnosed as having chronic intestinal pseudo-obstruction with manometric and histopathologic features suggestive of an intestinal myopathy. Histology was characterized by smooth muscle degeneration without inflammatory or immune cells. The severe gut dysfunction required full parenteral nutritional support. After a few months, the patient developed symptomatic tachy-brady ...
Sikowitz Megan D MD Department of Chemistry and Chemical Biology, Cornell University , Ithaca, New York 14853, United - - 2013
Thiaminases are responsible for the degradation of thiamin and its metabolites. Two classes of thiaminases have been identified based on their three-dimensional structures and their requirements for a nucleophilic second substrate. Although the reactions of several thiaminases have been characterized, the physiological role of thiamin degradation is not fully understood. ...
Martinelli A - - 2013
Magnetization measurements and neutron powder diffraction analyses followed by Rietveld refinement have been carried out in order to investigate the magnetic structures of LaYbO3 and LaHoO3. Both compounds exhibit a negative thermal expansion along the a and b axes. In LaYbO3 Yb(3+) spins order at 2.4 K according to a FyGz-type ...
Shao J M - - 2013
We have theoretically studied the longitudinal dc conductivity of the surface state of three-dimensional (3D) topological insulators (TIs) under a linearly polarized (LP) terahertz (THz) field irradiation via the Floquet theory and Green's function technique. It was found that, due to the anisotropic quasienergy spectrum under the LP light, the ...
Gordon J M - - 2013
A common problem of nonradiative energy transfer (NRET) from a small energy donor into a neighbouring energy acceptor layer is addressed with the emphasis on the layer thickness dependence. Two complementary approaches are employed to study dielectric polarization effects on NRET into thin films: a macroscopic analysis treating the acceptor ...
Vrtnik S - - 2013
Large-unit-cell complex metallic alloys (CMAs) frequently achieve stability by lowering the kinetic energy of the electron system through formation of a pseudogap in the electronic density of states (DOS) across the Fermi energy εF. By employing experimental techniques that are sensitive to the electronic DOS in the vicinity of εF, ...
Miller Daniel S DS Department of Chemical and Biological Engineering, University of Wisconsin-Madison , 1415 Engineering Drive, Madison, Wisconsin 53706, United - - 2013
We report the use of flow cytometry to identify the internal ordering (director configurations) of micrometer-sized droplets of thermotropic liquid crystals (LCs) dispersed in aqueous solutions of adsorbates (surfactants and phospholipids). We reveal that changes in the configurations of the LC droplets induced by the adsorbates generate distinct changes in ...
Alvarez-Diaz J A - - 2013
INTRODUCTION. The neurosciences have developed at a stunningly fast rate. Key points accounting for this progression include the introduction of functional neuroimaging techniques and the boost resulting from the Decade of the Brain project. This expansion has also allowed new disciplines such as neuroethics to appear. DEVELOPMENT. Those who have ...
Oreja-Guevara C - - 2013
INTRODUCTION. Multiple sclerosis is a chronic neurological inflammatory demyelinating disease. Specialists involved in the symptomatic treatment of this disease tend to apply heterogeneous diagnostic and treatment criteria. AIM. To establish homogeneous criteria for treating spasticity based on available scientific knowledge, facilitating decision-making in regular clinical practice. DEVELOPMENT. A group of ...
Canneti B - - 2013
INTRODUCTION. CLIPPERS syndrome (chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids) is an inflammatory process of the central nervous system whose distinguishing features are the enhancing punctiform lesions in the brainstem that appear in the magnetic resonance images. Clinically, it is accompanied by dysarthria, ataxia and diplopia, and ...
Gracia-Naya M - - 2013
INTRODUCTION. Topiramate and onabotulinumtoxin A have proven to be effective in chronic migraine with or without medication abuse according to recent criteria of the International Headache Society's Headache Classification. AIMS. To show that flunarizine is as effective as topiramate in cases of chronic migraine without medication abuse. PATIENTS AND METHODS. ...
Esteba-Castillo S - - 2013
INTRODUCTION. Dementia caused by Alzheimer's disease commonly affects the adult population with Down's syndrome. This population presents two characteristic clinical features: a semiologic pattern that differs from the typical Alzheimer's disease, and previous intellectual deficits that may confound the clinical diagnosis. There is a clear need to validate specific instruments ...
Stein Louis H - - 2013
Pharmacologic interventions for thoracic aneurysms remain poorly characterized. The results of a pilot study by our group suggested improved outcomes among patients with thoracic aortic aneurysm who were taking statins. In the present study, we undertook a comprehensive analysis of a larger cohort of patients from the Database of the ...
Canepa Marco M Division of Cardiology, Johns Hopkins University, Baltimore, Maryland; Longitudinal Studies Section, Translational Gerontology Branch, National Institute on Aging, National Institute of Health, Baltimore, Maryland; Division of Cardiology, Research Center of Cardiovascular Biology, University of Genova, - - 2013
Obesity is independently associated with left ventricular (LV) hypertrophy and thus may be an important modifier of the hypertrophic cardiomyopathy (HC) phenotype. We examined if obesity modifies the clinical presentation, LV morphology, outflow hemodynamics, and exercise tolerance in HC. In this cross-sectional study, 88 obese (body mass index [BMI] ≥30 ...
Mahmoud Waleed E WE Faculty of Science, Physics Department, King Abdulaziz University , Jeddah, Saudi - - 2013
Here, we report the synthesis, characterization, and properties of Fe/Fe3O4 core-shell nanocubes prepared via a simple route. It includes NaBH4 reduction of FeCl3 in an ethylene glycol solution in the presence of 2-mercaptopropionic acid (surfactant) and trisodium citrate (cosurfactant) followed by surface oxidation with trimethylamine N-oxide. The morphology and structure ...
- - 2013
The World Health Organization (WHO)-coordinated Global Invasive Bacterial Vaccine-Preventable Diseases (IB-VPD) sentinel hospital surveillance network provides data for decision making regarding use of pneumococcal conjugate vaccine and Haemophilus influenzae type b (Hib) vaccine, both recommended for inclusion in routine childhood immunization programs worldwide. WHO recommends that countries conduct sentinel hospital ...
- - 2013
Mycobacterium tuberculosis, the bacterium that causes tuberculosis (TB), is spread from person to person by the airborne route. It can be transmitted extensively in congregate settings, making investigating exposures and treating infected contacts challenging. In December 2011, a student at a Colorado high school with 1,381 students and school personnel ...
Miller Zachary D ZD Department of Chemistry, University of Michigan , 930 North University Avenue, Ann Arbor, Michigan 48109-1055, United - - 2013
Regioselective methods for allene hydrosilylation have been developed, with regioselectivity being governed primarily by the choice of metal. Alkenylsilanes are produced via nickel catalysis with larger N-heterocyclic carbene (NHC) ligands, and allylsilanes are produced via palladium catalysis with smaller NHC ligands. These complementary methods allow either regioisomeric product to be ...
Hosokawa Yoshitaka - - 2013
CC chemokine ligand 20 (CCL20) plays a central role in the recruitment of CCR6-expressing cells, including Th17 cells which are related to bone resorption in periodontal lesions and thus in the development of periodontal disease. IL-6 is an important cytokine that is associated with the pathogenesis of periodontitis. However, the ...
Entry James A - - 2013
Half of the original Everglades system has been lost to drainage and development. What remains is included within the boundaries of the Everglades Protection Area (EPA), comprised of three Water Conservation Areas (WCAs) and Everglades National Park (Park). Inflows to the EPA contain elevated nutrient concentrations. Best management practices (BMPs) ...
Alam Murad - - 2013
IMPORTANCE Detailed information regarding perioperative risk and adverse events associated with Mohs micrographic surgery (MMS) can guide clinical management. Much of the data regarding complications of MMS are anecdotal or report findings from single centers or single events. OBJECTIVES To quantify adverse events associated with MMS and detect differences relevant ...
Zhu Yihao - - 2013
The purpose of this study was to investigate the effect of manganese (Mn)-induced cytotoxicity on heat shock proteins in chicken spleen lymphocytes. Lymphocytes were cultured in medium in the absence and presence of MnCl2 (2 × 10(-4), 4 × 10(-4), 6 × 10(-4), 8 × 10(-4), 10 × 10(-4), and 12 × 10(-4) mmol/L) for 12, 24, 36, and 48 h in vitro. Then, ...
Idorn Luise Winkel - - 2013
IMPORTANCE UV radiation (UVR) exposure is the primary environmental risk factor for developing cutaneous malignant melanoma (CMM). OBJECTIVE To measure changes in sun behavior from the first until the third summer after the diagnosis of CMM using matched controls as a reference. DESIGN, SETTING, AND PARTICIPANTS Three-year follow-up, observational, case-control ...
Rasouli Mina - - 2013
Enteroendocrine cells are the largest population of hormone-producing cells in the body and play important roles in many aspects of body functions. The enteroendocrine cell population is divided into different subpopulations that secrete different hormones and peptides. Characterization of each subpopulation is particularly useful for analyzing the cellular mechanisms responsible ...
Liu Chibo - - 2013
This study aims to explore the apoptotic function of shikonin on the papillary thyroid cancer cells and the related mechanism. The papillary thyroid cancer cell lines K1 and W3 and thyroid follicular epithelial cells NTHY-ORI 3-1 were treated with different concentrations of shikonin. Cell proliferation was tested. Morphological changes of ...
Pomicter A D - - 2013
Mice incapable of synthesizing the myelin lipid sulfatide form paranodes that deteriorate with age. Similar instability also occurs in mice that lack contactin, contactin-associated protein or neurofascin155 (Nfasc155), the proteins that cluster in the paranode and form the junctional complex that mediates myelin-axon adhesion. In contrast to these proteins, sulfatide ...
Tawfik Ahmed M - - 2013
To evaluate whether dual-energy computed tomography (DECT)-derived iodine content and iodine overlay could differentiate between normal, inflammatory and metastatic squamous cell carcinoma (SCC) cervical lymph nodes. This study was approved by the institutional review board. Sixteen patients with normal lymph nodes, 20 patients with enlarged nodes draining deep cervical inflammations ...
Ko Kyung Hee - - 2013
To report our preliminary experience with shear-wave elastography (SWE) for non-mass lesions (NMLs) in the breast and suggest a potential ancillary role of SWE for BI-RADS Category 4a NMLs in reducing the number of unnecessary benign biopsies. A total of 310 breast lesions in 286 consecutive women who had been ...
Botsikas Diomidis - - 2013
To investigate the added advantage of IV furosemide injection and the subsequent urine dilution in the detection of urinary calculi in the excretory phase of dual-source dual-energy (DE) computed tomography (CT) urography, and to investigate the feasibility of characterising the calculi through diluted urine. Twenty-three urinary calculi were detected in ...
Haneder Stefan - - 2013
To evaluate the feasibility of in vivo (23)Na imaging of the corticomedullary (23)Na gradient and to measure (23)Na transverse relaxation times (T2*) in human kidneys. In this prospective, IRB-approved study, eight healthy volunteers (4 female, 4 male; mean age 29.4 ± 3.6 years) were examined on a 7-T whole-body MR system using a ...
Chen Chien-Ming - - 2013
To evaluate CT aortography at reduced tube voltage and contrast medium dose while maintaining image quality through iterative reconstruction (IR). The Institutional Review Board approved a prospective study of 48 patients who underwent follow-up CT aortography. We performed intra-individual comparisons of arterial phase images using 120 kVp (standard tube voltage) and ...
Steff Maud - - 2013
IMPORTANCE Curative treatment of aggressive Kaposi sarcoma (KS) with conventional chemotherapy in human immunodeficiency virus (HIV)-infected patients remains difficult. The administration of thalidomide, an immunomodulatory drug with antiangiogenic effects, is limited by its toxicity. This engenders interest in evaluating thalidomide analogues such as lenalidomide with better toxicity profiles. To our ...
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