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Results 251 - 300 of 3167
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Hsiao Yu-Ping - - 2013
The lack of a human papillomavirus (HPV)-infected skin cancer cell line has hampered the investigation of the interaction of UV and HPV in skin carcinogenesis. We identified a human basal cell carcinoma (BCC-1/KMC) cell line integrated with E6 and E7 genes of high-risk HPV type 18 and demonstrated that repression ...
Siegford Janice M - - 2013
Nonhuman animal welfare is a complex concept that encompasses an animal's biological functioning, emotional states, and opportunities to experience a natural life, including the performance of natural behaviors. Further, animal welfare can be viewed as quality of life from the perspective of the animal and thus must consider the animal's ...
Palmeri Mark - - 2013
The uterine cervix softens, shortens, and dilates throughout pregnancy in response to progressive disorganization of its layered collagen microstructure. This process is an essential part of normal pregnancy, but premature changes are associated with preterm birth. Clinically, there are no reliable noninvasive methods to objectively measure cervical softening or assess ...
Dennis Elise A - - 2013
Fundamental aspects of constant-momentum acceleration time-of-flight mass spectrometry (CMA-TOFMS) are explored as a means to improve mass resolution. By accelerating all ions to the same momentum rather than to the same energy, the effects of the initial ion spatial and energy distributions upon the total ion flight time are decoupled. ...
Bois Aaron J - - 2013
This article reviews the commonly used imaging modalities for evaluating the athlete with symptoms of shoulder instability, including radiography, computed tomography (CT), and CT arthrography, with an initial focus on magnetic resonance (MR) imaging and MR arthrography. Examples of common soft tissue and osseous lesions associated with instability are provided, ...
Li Mingfen - - 2013
Abstract We investigated the efficacy of motor imagery-based Brain Computer Interface (MI-based BCI) training for 8 stroke patients with severe upper extremity paralysis using longitudinal clinical assessments. The results were compared with those of a control group (n = 7) which only received FES (Functional Electrical Stimulation) treatment besides conventional ...
Platten M - - 2013
A clinically isolated syndrome (CIS) is a term which describes the first clinical onset of a potential multiple sclerosis (MS). It ought to be defined as an MS stage rather than a separate disease entity; however, with respect to the diagnostic work-up, differential diagnoses to be considered, prognostic factors for ...
Li Lingliang - - 2013
A new type of organic visible-blind UV-PDs is demonstrated by utilizing phosphorescent material Ir(III)bis[(4,6-difluorophenyl)-pyridinato-N, C<sup>2<sup>'</sup> </sup>] picolinate (FIrpic) as the electron donor and [6,6]-phenyl-C-61-butyricacidmethylester (PCBM) as the electron accepter, respectively. The peak responsivity of the organic UV-PDs is as high as 140  mA/W, corresponding to an external quantum efficiency of about ...
Khushf George - - 2013
This essay considers implications of formal mereologies and ontologies for medical metaphysics. Edward Fried's extensional mereological account of the human body is taken as representative of a prominent strand in analytic metaphysics that has close affinities with medical positivism. I show why such accounts fail. First, I consider how Fried ...
McKeever Amy E AE College of Nursing, Villanova University in - - 2013
Pharmaceutical drug shortages are multifaceted and complex problems that affect all aspects of health care, including patients, caregivers, healthcare providers, third-party payers, the pharmaceutical industry, and regulators. Drug shortages have increased significantly since 2000, which cause increases in healthcare costs and compromised patient care. New government regulations have led the ...
- - 2013
This policy statement serves to combine and update 2 previously independent but overlapping statements from the American Academy of Pediatrics (AAP) on culturally effective health care (CEHC) and workforce diversity. The AAP has long recognized that with the ever-increasing diversity of the pediatric population in the United States, the health ...
Estrada Raquel Vidal - - 2013
The aim of the present study was to assess the efficacy of psychoeducation as compared with cognitive behavioral group therapy in adults with attention deficit hyperactivity disorder (ADHD) who still had significant symptoms and were in pharmacological treatment. This is the first study on psychoeducation in adults with ADHD. Thirty-two ...
Tajbakhsh Sharareh - - 2013
Documentation of long-term changes in food intake is lacking for those treated with a maxillary complete denture opposed by a mandibular, screw-retained, implant-supported fixed prosthesis. The purpose of this study was to evaluate the selection patterns of dietary foods over 5 years for edentulous participants treated in a multicenter prospective ...
Cuddeback Gary S - - 2013
OBJECTIVE More research is needed about forensic assertive community treatment (FACT) and challenges that offenders with severe mental illness present to jail diversion and prison reentry teams. Jail diversion and prison reentry populations may require different interventions and strategies to engage and serve them. METHODS This study used data from ...
McPartland Sarah J - - 2013
Cytoreductive surgery with hyperthermic intraperitoneal chemotherapy (CRS-HIPEC) can prolong survival in peritoneal-based malignancies. These malignancies harbor in visceral and omental adipose tissue, and as a result, obesity may contribute to greater tumor burden. Obesity also is an independent risk factor for perioperative complications following major surgery. No studies to date ...
Langslet Ellen - - 2013
Displaced femoral neck fractures usually are treated with hemiarthroplasty. However, the degree to which the design of the implant used (cemented or uncemented) affects the outcome is not known and may be therapeutically important. In this randomized controlled trial, we sought to compare cemented with cementless fixation in bipolar hemiarthroplasties ...
Kin Kevin C - - 2013
The Centers for Disease Control and Prevention recommend screening for hepatitis C virus (HCV) in patients with injection drug use, blood transfusion before 1992, stigmata of liver disease, or born between 1945 and 1965. The purpose of this study was to examine risk factors for HCV acquisition in Asian Americans. ...
Nikodem Michal - - 2013
In this Letter, a dispersion-based gas sensing method applied to detection of optically thick samples is presented. We show that chirped laser dispersion spectroscopy (CLaDS) technique provides perfectly linear signal response over a wide range of target analyte concentrations. Using the most convenient chirp-modulated CLaDS detection scheme, it enables spectroscopic ...
Shimizu Miho - - 2013
Diabetic nephropathy is a leading cause of end-stage renal disease in Japan. Microalbuminuria has been considered as the first clinical sign of diabetic nephropathy. However, recent studies demonstrated that normoalbuminuric renal insufficiency is not uncommon for diabetic patients, especially in type 2 diabetes. Although the pathogenesis of normoalbuminuric renal insufficiency ...
Kołodziejczak M - - 2013
Organic or functional anal canal stenoses are uncommon conditions that occur in the majority of cases as a consequence of anal diseases. A proper assessment is fundamental for decision making; however, proctological examination and endoanal ultrasound are often unfeasible or very difficult to perform even under local or general anesthesia. ...
Courtier Jesse - - 2013
The chronic nature of inflammatory bowel disease (IBD) creates a lifelong effect on the morbidity of children affected by the disease. The ability to confidently identify and characterize complications resulting from IBD in the pediatric patient is of critical importance. Magnetic resonance enterography (MRE) is especially valuable in the diagnostic ...
Irwin Margaret M - - 2013
The Oncology Nursing Society (ONS) and ONS Foundation worked together to develop the Institute for Evidence-Based Practice Change (IEBPC) program to facilitate the implementation of evidence-based practice (EBP) change in nursing. This analysis describes the experience of 19 teams of nurses from various healthcare settings who participated in the IEBPC ...
den Daas Chantal - - 2013
In the heat of the moment, people often impulsively take risks. Having unprotected sex, for example, can result in sexually transmitted infections. In three studies, we investigated a possible explanation for the increased sexual risk propensity of people in an impulsive state. In contrast to the intuitively appealing notion that ...
Bergin Junping Ma - - 2013
Conventional impression techniques for recording the location and orientation of implant-supported, complete-arch prostheses are time consuming and prone to error. The direct optical recording of the location and orientation of implants, without the need for intermediate transfer steps, could reduce or eliminate those disadvantages. The objective of this study was ...
Knecht Pascal B - - 2013
In this single-centre retrospective case review, we investigate the long-term follow-up of birdshot retinochoroiditis (BRC) patients, analysing the impact of early, vigorous, and prolonged treatment on the evolution of indocyanine green angiography (ICGA) signs and fundus appearance. Treatment delay was calculated for each BRC patient, and patients were classified into ...
Lim Dooyoung - - 2013
OBJECTIVES This study examined national trends in antidepressant use before and after implementation of Medicare Part D and compared utilization among individuals with different types of insurance. METHODS The data source was the Medical Expenditure Panel Survey Household Component (1997-2009), and logistic regression was used for the analysis. RESULTS The ...
Mazzeo Teresa - - 2013
Abstract The purpose of this study was to investigate the visual and taste liking of three commercial gluten-free (GF) foods in a group of celiac children. Thirty celiac children, with diagnosis of celiac disease from more than 2 years, were recruited and 28 (21 females and 7 males, mean age ...
Yu Yang - - 2013
Green tea catechins have been extensively studied for their cancer preventive effects. Accumulating evidence has shown that green tea catechins, like (-)-epigallocatechin-3-gallate, have strong anti-oxidant activity and affect several signal transduction pathways relevant to cancer development. Here, we review the biological properties of green tea catechins and the molecular mechanisms ...
Kempen Gertrudis I J M - - 2013
Vision loss is highly prevalent in old age and has a substantial impact on different aspects of quality of life including depressive symptoms. Our objective was to examine the mediating role of disability and social support in the association between low vision and depressive symptoms. Differences in disability, social support, ...
Ozdemir Abdil - - 2013
A novel self-powered dual spray ionization source has been developed for applications in mass spectrometry. This new source does not use any power supply and produces both positive and negative ions simultaneously. The idea behind this ionization source comes from the Kelvin water dropper. The source employs one or two ...
Iqbal Qumer - - 2013
Studies were conducted to investigate the accumulation pattern of capsaicinoids and antioxidants such as carotenoids, ascorbic acid and phenolic compounds in three hot pepper hybrids at five different harvesting stages: immature green, mature green, color break, red ripe and dried fruit. Capsaicin and dihydrocapsaicin contents were maximum at mature green ...
Nunomura Wataru - - 2013
Calmodulin (CaM) binds to the FERM domain of 80 kDa erythrocyte protein 4.1R (R30) independently of Ca(2+) but, paradoxically, regulates R30 binding to transmembrane proteins in a Ca(2+)-dependent manner. We have previously mapped a Ca(2+)-independent CaM-binding site, pep11 (A(264)KKLWKVCVEHHTFFR), in 4.1R FERM domain and demonstrated that CaM, when saturated by Ca(2+) ...
Wu Xiang-Song - - 2013
Survival after surgery for gallbladder cancer is generally poor. A number of inflammation-based prognostic scores have been established to help predict survival after surgery for several types of cancer. The objective of this study was to analyze and compare the utility of two inflammation-based prognostic scores, the Glasgow prognostic score ...
Kwa Maryann - - 2013
Ovarian cancer arising in women with BRCA mutations is known to have a more favorable outcome and to be more responsive to platinum-based regimens than in those without a hereditary background. We analyze our previously published intraperitoneal (IP) studies in relation to BRCA mutation status and update their outcomes. Among ...
Lion Thomas - - 2013
In patients with chronic myeloid leukemia, high-quality diagnostics is of paramount importance for the surveillance of treatment efficacy. The availability of new tyrosine kinase inhibitors providing more rapid and deeper responses requires the employment of standardized and highly sensitive diagnostic methods to ensure optimal monitoring of the patients. This review ...
Rueda E - - 2013
In the present work, we propose a method to generate high-quality optical vortices with a reduced number of phase levels by using multilevel vortex-producing lenses (VPLs). The VPL is implemented in a liquid-crystal spatial light modulator with limited capacity to project phase levels. The proposed method significantly improves the quality ...
Hailer Nils P - - 2013
Pseudotumors and immunologic alterations are reported in patients with elevated metal ion levels after resurfacing arthroplasty of the hip. A direct association of increased cobalt and chromium concentrations with the development of pseudotumors has not been established. We hypothesized that (1) patients with higher blood cobalt and chromium concentrations are ...
Sugawara Kayoko - - 2013
The significance of retinopathy during triple therapy with telaprevir is uncertain. Ophthalmologic examination was done prospectively before and every month during the therapy in 95 CHC patients. Retinopathy was found in 46 (48.4 %), and the specialists recommended discontinuation of the therapy in 9 (9.5 %). Such lesions may develop as adverse ...
Thursz Mark - - 2013
HCV is a blood-borne virus transmitted by percutaneous exposure to infected blood or blood-derived body fluids. The main routes of transmission are blood transfusions, medical procedures and injection drug use. In industrialized countries, HCV transmission through blood transfusions has been virtually eliminated and iatrogenic transmission occurs only sporadically during local ...
Van Gerpen Ruth E - - 2013
Cancer-related fatigue is one of the most common and distressing side effects experienced by patients with cancer. Increased activity and exercise have been shown to significantly impact cancer-related fatigue and are beneficial during and after treatment. This article describes the development and implementation of a 12-week evidence-based exercise and education ...
Veasey Sigrid C SC Center for Sleep and Circadian Neurobiology, University of Pennsylvania, Philadelphia, - - 2013
Exposure to the variable oxygenation patterns in obstructive sleep apnea (OSA) causes oxidative stress within the brain. We hypothesized that this stress is associated with increased levels of redox-active metals and white matter injury. Participants were randomly allocated to a control or experimental group (single independent variable). University animal house. ...
Skoczylas Laura C - - 2013
In 2008 and 2011, the US Food and Drug Administration (FDA) released notifications regarding vaginal mesh. In describing prolapse surgery trends over time, we predicted vaginal mesh use would decrease and native tissue repairs would increase. Operative reports were reviewed for all prolapse repairs performed from 2008 to 2011 at ...
Shi Zumin - - 2013
Famine exposure during the early stage of life is related to a number of adulthood diseases. The objective of this study was to examine the association of early life exposure to the famine in China (1959--1961) with the risk of anaemia in adulthood. We used the data of 2007 adults ...
Gonen Ofer Michael - - 2013
Sandfly viruses are arthropod-borne viruses that are endemic in the Mediterranean basin. The Toscana virus (TOSV) is the only serotype of sandfly viruses known to cause neurological symptoms in humans, usually aseptic meningitis or meningoencephalitis. We report a case of a 39-year-old man who was admitted to our department with ...
Sawadkar Prasad - - 2013
The traumatic rupture of tendons is a common clinical problem. Tendon repair is surgically challenging because the tendon often retracts, resulting in a gap between the torn end and its bony insertion. Tendon grafts are currently used to fill this deficit but are associated with potential complications relating to donor ...
Koh Kyung Min - - 2013
To compare the success rates, complications, and visual outcomes between silicone Ahmed glaucoma valve (AGV) implantation with 96 mm(2) (FP8) or 184 mm(2) (FP7) surface areas. This study is a retrospective review of the records from 132 adult patients (134 eyes) that underwent silicone AGV implant surgery. Among them, the ...
Joshi Mithun A - - 2013
Recurrent anterior shoulder instability is common in contact athletes and the high-energy injuries seen in this group make them more prone to bone loss. Athletes with recurrent instability and associated bone loss have high failure rates when treated with a soft tissue reconstruction procedure. Therefore it is preferred to manage ...
Scott William W - - 2013
Endometriosis is a common disease; however, ectopic müllerian tissue within the spine is a rare entity with the potential for producing significant neurological compromise. There are several postulated etiologies for this phenomenon, and only a few case reports are available in the world literature. Knowledge of this rare phenomenon is ...
Cuadrado Alexander - - 2013
This Letter shows the effect of the geometrical and material properties of lead lines and connections on the robustness and reliability of optical antennas working as distributed bolometers. We analyze the operational limits of the biasing voltage using a mutiphysics finite element method. We demonstrate that, after evaluating the effect ...
Tan Sisi - - 2013
We propose and experimentally demonstrate a feasible integrated scheme to solve all-optical differential equations using microring resonators (MRRs) that is capable of solving first- and second-order linear ordinary differential equations with different constant coefficients. Employing two cascaded MRRs with different radii, an excellent agreement between the numerical simulation and the ...
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