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Lim Tae Kang - - 2013
To investigate the outcomes of vascularized distal radius pedicled bone grafting secured with K-wires for scaphoid nonunions with small avascular proximal fragments. We included patients with scaphoid nonunions and small, avascular proximal fragments that were too small for screw fixation. The mean size of the proximal pole fragments was 21% ...
Del Piñal Francisco - - 2013
To present our experience of reconstructing distal radius articular defects with a vascularized osteochondral graft from the metatarsal base and to present the mid-term outcomes. Seven patients (average age, 36 y; range, 26-55 y) who had reconstruction of major defects of the articular surface of the radius are presented. In ...
Chan Yau-Chi - - 2013
While human embryonic stem cells (hESCs) can differentiate into functional cardiomyocytes, their immature phenotypes limit their therapeutic application for myocardial regeneration. We sought to determine whether electrical stimulation could enhance the differentiation and maturation of hESC-derived cardiomyocytes. Cardiac differentiation was induced in a HES3 hESC line via embryoid bodies formation ...
Sadhasivam S - - 2013
A highly sensitive detection of breast cancer marker, carbohydrate antigen 15-3 (CA 15-3) by carbon nanotube (CNT) based immuno-polymerase chain reaction was reported. The study was aimed to develop a precise and sensitive method to diagnose breast cancer and its recurrence. The hydrofluoric acid (HF) treated silicon wafer layered with bundled ...
Shadanbaz Shaylin - - 2013
The use of magnesium (Mg) as a biodegradable metallic replacement of permanent orthopaedic materials is a current topic of interest and investigation. The appropriate biocompatibility, elastic modulus and mechanical properties of Mg recommend its suitability for bone fracture fixation. However, the degradation rates of Mg can be rapid and unpredictable ...
Xu Bin - - 2013
Context.-Enhancer of zeste homolog 2 (EZH2), a histone methyltransferase mediating chromatin condensation and epigenetic modulation, is overexpressed in various human carcinomas and is associated with adverse clinicopathologic characteristics and biologic behavior. The expression of EZH2 in renal cell carcinomas (RCCs) has not been fully characterized yet. Objective.-To evaluate the prognostic ...
Koo Brian B - - 2013
The duration of an obstructive apnea is dependent on gender, age, body position, and state. Termination of an obstructive respiratory event is attributed as the end result of an achieved specific negative inspiratory force, sufficient to result in cortical arousal. We used polysomnographic measures of tendency for arousal, hypothesizing that ...
Han Ying - - 2013
Non-alcoholic fatty liver disease (NAFLD) is associated with a high morbidity in patients with impaired fasting glucose (IFG). Bicyclol is a synthetic compound known to protect the liver against oxidation and lipid injuries. The objective of this study was to evaluate the efficacy and safety of metformin and bicyclol in ...
Sairaku Akinori - - 2013
Two new oral anticoagulants, rivaroxaban and dabigatran, with no need for anticoagulation monitoring, are available for patients with atrial fibrillation (AF). We aimed to compare their anticoagulant effects and safety when used during the AF ablation periprocedural period. Patients undergoing AF ablation were randomly assigned to receive rivaroxaban 15 mg once ...
Izu Suemy Cioffi - - 2013
The aim of this study was to validate the Rhinoplasty Outcomes Evaluation (ROE) questionnaire adapted to the Brazilian Portuguese. A prospective study was conducted with ROE administration to 56 patients submitted to rhinoplasty (preoperatively, and then 15-day and 90-day postoperatively) and 100 volunteers without the need or desire of cosmetic ...
Feng Yan - - 2013
The study aims to increase knowledge about the performance of the EuroQol-visual analogue scales (EQ-VAS) in the UK NHS patient-reported outcome measures (PROMs) programme, which covers groin hernia, hip and knee replacement and varicose vein surgery, and make suggestions for improved collection, coding and analysis of data. Four hundred scanned ...
Zeng Xue - - 2013
Psoriasis is an inflammatory, immune-mediated disease of the skin. Several studies have suggested that natural killer (NK) cells and their receptors may be important for its pathogenesis. Here, we examined whether deletion of the activating natural killer receptor gene NKG2C, which has a frequency of 20% in the European population, ...
Sigruener Alexander - - 2013
Keratinocyte sphingolipids are structural elements of epidermal permeability barrier and potential regulators of epidermal functions. We tested the influence of sphingoid bases sphinganine, sphingosine and phytosphingosine on in vitro keratinocyte differentiation. Lipidomic and transcriptomic analysis after treatment emphasizes sphinganine and phytosphingosine as potent modulators of keratinocyte differentiation and lipid metabolism. ...
Li Jie - - 2013
A porcine deep partial-thickness wound model was used to evaluate the effects of a newly developed topical aqueous oxygen emulsion (TOE) on wound repair. The wounds were treated with TOE, which contains super-saturated oxygen or vehicle control. Semiquantitative immunofluorescent staining was performed to examine protein production for type I and ...
Hsiao Yu-Ping - - 2013
The lack of a human papillomavirus (HPV)-infected skin cancer cell line has hampered the investigation of the interaction of UV and HPV in skin carcinogenesis. We identified a human basal cell carcinoma (BCC-1/KMC) cell line integrated with E6 and E7 genes of high-risk HPV type 18 and demonstrated that repression ...
Arai Iwao - - 2013
We investigated the effects of a single dose of mouse interleukin-31 (IL-31) on scratching behaviour in comparison with spontaneous skin-lesion- or serotonin (5-HT)- induced scratching behaviour in NC/Nga and BALB/c mice. Intradermal (i.d.) injection of IL-31 caused a gradual increase in long-lasting scratching (LLS, over 1.5 s) about 3 h after administration ...
van Bragt S - - 2013
To assess psychometric properties of the Pelican instrument, an online Dutch self-administered Quality of Life instrument for childhood asthma for scientific and clinical use. A cohort study was done in two asthma populations and healthy children. One asthma population had assessment at start, 4 and 8 weeks. The other asthma population ...
Dahlhoff Maik - - 2013
The epidermal growth factor receptor (EGFR) system is an established regulator of the development and homeostasis of the hair follicle and interfollicular epidermis. Here, we evaluated EGFR actions on the sebaceous glands (SGs) by employing Dsk5 mice, a mutant line in which the EGFR is constitutively activated in a ligand-independent ...
Stern Christina - - 2013
Preeclampsia (PE) is a serious life event that can change women's psychological profile. The aim of this study was to evaluate the physical and mental health-related quality of life (HR-QoL) in women after PE and the impact of contributing factors. Ninety-five women who had suffered from PE answered the Short-Form-12 ...
Koene Paul - - 2013
This project aimed to estimate a species' adaptations in nature and in captivity, assess welfare, suggest environmental changes, and find species characteristics that underlie welfare problems in nonhuman animals in the zoo. First, the current status of zoo animal welfare assessment was reviewed, and the behavioral ecology approach was outlined. ...
Hosey Geoff - - 2013
Contact with people, both familiar (e.g., caretakers) and unfamiliar (e.g., members of the public), is a significant part of the lives of nonhuman animals in zoos. The available empirical evidence shows that in many cases this contact represents a source of stress to the animals, although there is sufficient overall ...
Carlstead Kathy - - 2013
Multi-institutional studies of welfare have proven to be valuable in zoos but are hampered by limited sample sizes and difficulty in evaluating more than just a few welfare indicators. To more clearly understand how interactions of husbandry factors influence the interrelationships among welfare outcomes, epidemiological approaches are needed as well ...
Siegford Janice M - - 2013
Nonhuman animal welfare is a complex concept that encompasses an animal's biological functioning, emotional states, and opportunities to experience a natural life, including the performance of natural behaviors. Further, animal welfare can be viewed as quality of life from the perspective of the animal and thus must consider the animal's ...
Xavier Stephanie P - - 2013
Notch pathway genes have been implicated in the commitment of mesenchymal cells to a wool follicle cell fate. Notch1 and Delta1 transcripts were quantified in fetal skin of fine-woolled (Merino) and strong-woolled (Tukidale) sheep at two time points: either preceding (d56) or during (d70) the first wave of follicle initiation. ...
Toberer Ferdinand - - 2013
Cutaneous lupus erythematosus (CLE) is a heterogeneous autoimmune disease. Different pathogenetic mechanisms, including the accumulation of apoptotic keratinocytes in CLE, have been reported. Therefore, we investigated whether CLE and other inflammatory skin diseases differ with regard to the epidermal expression of molecules that are crucial for the initiation and regulation ...
Kotzerke Kristina - - 2013
It has long been known that keratinocytes influence cutaneous immunity through secretion of soluble factors. Exosomes, small membrane vesicles of endocytotic origin, have been implicated in intercellular communication processes such as the transfer of tumor cell antigens and the activation of recipient dendritic cells (DC). However, little is known about ...
Luke Courtney T - - 2013
Hairless (HR) is a nuclear protein with corepressor activity that is highly expressed in the skin and hair follicle. Mutations in Hairless lead to hair loss accompanied by the appearance of papules (atrichia with papular lesions), and similar phenotypes appear when the key polyamine enzymes ornithine decarboxylase (ODC) and spermidine/spermine ...
Hinde Eleanor - - 2013
The skin of most mammals is characterised by the presence of sebaceous glands (SGs), whose predominant constituent cell population is sebocytes, that is, lipid-producing epithelial cells, which develop from the hair follicle. Besides holocrine sebum production (which contributes 90% of skin surface lipids), multiple additional SG functions have emerged. These ...
McVittie Chris - - 2013
We examine from a discursive perspective momentary confabulations generated by patients in clinical interviews based on confabulation questionnaires. Commonly, neuropsychology treats such confabulations solely as evidence of patients' inabilities or deficits. Here we argue that patients' descriptions indicate the interaction of memory deficits with preserved interactional skills. More than this, ...
Singh Brij - - 2013
The propagation of shear-horizontal (SH) waves is studied for a functionally gradient magnetoelectric (ME) material. The material properties of the ME half-space are normal to the free surface. The ME open conditions are applied to the free surface. Dispersion relations are obtained in explicit form for different forms of the ...
Nakazawa Marie - - 2013
In this paper, we present a polyurea transducer that works at 100 MHz under water. The transducer was designed using an equivalent circuit model so that an aluminum (top)-polyurea-aluminum (bottom)-polyimide layer had a resonant frequency of 100 MHz and output sound pressure became maximum at that frequency. The thicknesses of ...
Toprak Alperen - - 2013
This paper presents a novel optimization method for interdigitated electrode (IDE)-based, cantilever-type piezoelectric energy harvesters at microelectromechanical system (MEMS) scale. A new two-stage approach based on the finite element method is proposed to examine the performance of such devices. First, detailed electrostatic poling simulations are presented. The results of these ...
Bartsch Stephen - - 2013
A protocol was originally designed to study breathing control during and following cardiac arrest in humans, taking advantage of the period of pulseless ventricular fibrillation (PVF) produced while testing a newly implanted cardioverter-defibrillator device. A patient aged in his 60s with New York Heart Association class III heart failure (HF) ...
Wang Yujue - - 2013
A power harvester with adjustable frequency, which consists of a hinged¿hinged piezoelectric bimorph and a concentrated mass, is studied by the precise electric field method (PEFM), taking into account a distribution of the electric field over the thickness. Usually, using the equivalent electric field method (EEFM), the electric field is ...
Kadota Michio - - 2013
Currently, an ultra-wideband resonator is greatly needed to realize a tunable filter with a wide tunable range, because mobile phones with multiple bands and cognitive radio systems require such tunable filters to simplify their circuits. Although tunable filters have been studied using SAW resonators, their tunable range was insufficient for ...
Nikolovski Jean-Pierre - - 2013
Tactile sensing is widely used in human-computer interfaces. However, mechanical integration of touch technologies is often perceived as difficult by engineers because it often limits the freedom of style or form factor requested by designers. Recent work in active ultrasonic touch technologies has made it possible to transform thin glass ...
Nagpal Kamal - - 2013
The information provided during the postoperative handover influences the delivery of care of patients in the postoperative recovery unit through their care on the ward. There is a need for a structured and systematic approach to postoperative handover. The aim of this study was to improve postoperative handover through the ...
Perelli Alessandro - - 2013
Compressive sensing (CS) has emerged as a potentially viable technique for the efficient compression and analysis of high-resolution signals that have a sparse representation in a fixed basis. In this work, we have developed a CS approach for ultrasonic signal decomposition suitable to achieve high performance in Lamb-wave-based defect detection ...
Fiordelli Maddalena - - 2013
A good collaboration between health professionals is considered to have benefits for patients, healthcare staff, and organizations. Nevertheless, effective interprofessional collaboration is difficult to achieve. This is particularly true for collaboration between Medical Residents (MRs) and the immediate colleagues they interact with, as Senior Doctors (SDs) and Head Nurses (HNs). ...
Hanania Nicola A - - 2013
The goals of management of COPD include reducing exposure to risk factors; improving lung function, exercise tolerance, and quality of life; and decreasing exacerbations and mortality. Pharmacologic treatments, such as inhaled β2-agonists, anticholinergics, and inhaled corticosteroids, are widely used to help achieve these goals. In addition to efficacy, medication safety ...
Palmeri Mark - - 2013
The uterine cervix softens, shortens, and dilates throughout pregnancy in response to progressive disorganization of its layered collagen microstructure. This process is an essential part of normal pregnancy, but premature changes are associated with preterm birth. Clinically, there are no reliable noninvasive methods to objectively measure cervical softening or assess ...
Alkoy Sedat - - 2013
Textured ceramic fibers were fabricated from the tungsten-bronze-type piezoelectric (KSr2Nb5O15) . Development of crystallographic texture was evaluated through rocking curve analysis and a texture with Lotgering factor of 0.97 was achieved. 1-3 piezocomposites were prepared from the textured fibers and their electrical properties were evaluated. Highly enhanced properties that are ...
Nguyen Van - - 2013
This work presents for the first time a flexible over-moded resonator (OMR) based on P(VDF-TrFE) thin films. The devices were manufactured on commercially available elastic substrate with inkjet-printed electrodes. The sensing copolymer films used in the devices were polarized by the corona method after electrode deposition. The main performance parameters ...
Schols Annemie M W J - - 2013
COPD is an important global health problem. In addition to pulmonary impairment, systemic inflammation, musculoskeletal abnormalities, and cardiovascular comorbidity influence disease burden and mortality risk. Body weight and body composition are important discriminants in classifying disease heterogeneity. The rationale for and efficacy of caloric supplementation in preventing and treating involuntary ...
Lufi Dubi - - 2013
Fifty-nine adults slept five nights with an Actigraph and answered two questionnaires related to sleeping quality and morningness/eveningness preferences. Next they performed a computerized attention task (the mathematics continuous performance test (MATH-CPT)) to assess various measures of attention. Results showed significant correlations between six attention variables and two measures of ...
Manthous Constantine A - - 2013
Physicians are moving increasingly from self-employed, private practices to at-will employment relationships. This historic change in the organizational administration of medical services is likely to accelerate as the Affordable Care Act is implemented and as accountable care organizations permeate the medical marketplace. Physicians vow an ascendant oath to safeguard patients' ...
Rigby Barbara - - 2013
Cells derived from human embryonic stem cells have great therapeutic potential. Patents are key to allowing companies that develop methods of generating such cells to recuperate their investment. However, in Europe, inventions relating to the use of human embryos for commercial purposes are excluded from patentability on moral grounds. The ...
Tang Xianghu - - 2013
Here, Au nanoparticles (NPs) grafted on dendritic α-Fe2O3 (NPGDF) are designed as a highly uniform surface-enhanced Raman scattering (SERS) substrate with a feature of optical visualization by an optical microscope (OM) system and used for in situ detection of pesticide residues that are annually used in agriculture. With this strategy, ...
Wang Fei - - 2013
Cubic silver cages were prepared on monolithic activated carbon (MAC) pre-absorbed with Cl(-), SO4(2-), or PO4(3-) anions. Silver insoluble salts served as templates for the morphosynthesis of silver cages. The silver ions were reduced by reductive functional groups on MAC micropores through a galvanic cell reaction mechanism.
Kim Jae Min - - 2013
We report two cases of surgical removal of a retained subfoveal perfluorocarbon liquid (PFCL) bubble through a therapeutic macular hole combined with intravitreal PFCL injection and gas tamponade. Two patients underwent pars plana vitrectomy with PFCL injection for rhegmatogenous retinal detachment. In both cases, a retained subfoveal PFCL bubble was ...
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