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Krishnan Vinod V Professor, Department of Orthodontics, Sri Sankara Dental College, Trivandrum, Kerala, India. Electronic address: - - 2013
Publishing a scientific article in a journal with a high impact factor and a good reputation is considered prestigious among one's peer group and an essential achievement for career progression. In the drive to get their work published, researchers can forget, either intentionally or unintentionally, the ethics that should be ...
Teitelbaum Ezra N EN Department of Surgery, Northwestern University Feinberg School of Medicine, Chicago, - - 2013
Peroral esophageal myotomy (POEM) differs from laparoscopic Heller myotomy (LHM) in that only the circular muscle layer of the esophagus is divided, the hiatus is not mobilized, and an antireflux procedure is not performed. The effect of these differences on anatomic and functional outcomes is unknown. Patients who underwent LHM ...
Cherenfant Jovenel J NorthShore University HealthSystems, Evanston, IL. Electronic address: - - 2013
The biologic potential of nonfunctioning pancreatic neuroendocrine tumors (PNETs) is highly variable and difficult to predict before resection. This study was conducted to identify clinical and pathologic factors associated with malignant behavior and death in patients diagnosed with PNETs. We used International Classification of Diseases 9th edition codes to identify ...
Athanasiadis Yannis Y From the Moorfields Eye Hospital NHS Foundation Trust (Athanasiadis, Nithyanandarajah, Trivedy, Bishop, A. Sharma) and the Bedford School (B. Sharma), Bedford, United - - 2013
We describe a simple technique to create a peripheral surgical iridotomy using a microvitreoretinal blade. The blade passes perpendicular to the iris dilator fibers to create a permanent opening. No author has a financial or proprietary interest in any material or method mentioned.
Wilson Gregory C GC Department of Surgery, University of Cincinnati Pancreatic Disease Center, University of Cincinnati College of Medicine, Cincinnati, - - 2013
This study aims to review surgical outcomes of pediatric patients undergoing total pancreatectomy with islet cell autotransplantation (TP/IAT) for the treatment of chronic pancreatitis (CP). All pediatric patients (≤18 years old) undergoing TP/IAT over a 10-year period (December 2002-June 2012) were identified for inclusion in a single-center, observational cohort study. ...
Valenzuela G A GA Wayne State University, 10000 Telegraph Road, Taylor, Michigan 48124, - - 2013
The outcome of high tibial osteotomy (HTO) deteriorates with time, and additional procedures may be required. The aim of this study was to compare the clinical and radiological outcomes between unicompartmental knee replacement (UKR) and total knee replacement (TKR) after HTO as well as after primary UKR. A total of ...
Kirby M M The Centre for Research in Primary and Community Care (CRIPACC), University of Hertfordshire, Hatfield, Herts, - - 2013
To compare efficacy and tolerability between 100-mg and 50-mg sildenafil doses in five double-blind, placebo-controlled (DBPC) fixed-dose studies. Doses were compared for the change (baseline to end of 8-12 weeks of DBPC treatment) in score on the Erectile Function (EF) domain of the International Index of Erectile Function (IIEF; from ...
Mali Prashant P Department of Genetics, Harvard Medical School, Boston, Massachusetts, - - 2013
RNA-guided Cas9 nucleases derived from clustered regularly interspaced short palindromic repeats (CRISPR)-Cas systems have dramatically transformed our ability to edit the genomes of diverse organisms. We believe tools and techniques based on Cas9, a single unifying factor capable of colocalizing RNA, DNA and protein, will grant unprecedented control over cellular ...
Michels Karin B KB 1] Obstetrics and Gynecology Epidemiology Center, Department of Obstetrics and Gynecology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA. [2] Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts, - - 2013
Epigenome-wide association studies (EWAS) hold promise for the detection of new regulatory mechanisms that may be susceptible to modification by environmental and lifestyle factors affecting susceptibility to disease. Epigenome-wide screening methods cover an increasing number of CpG sites, but the complexity of the data poses a challenge to separating robust ...
Bosio Jose A JA Assistant professor, Department of Developmental Sciences/Orthodontics, School of Dentistry, Marquette University, Milwaukee, Wis. Electronic address: - - 2013
An 8-mm anterior and posterior open bite caused by a tongue rest posture habit was closed in a 25-year-old man by means of mandibular soldered tongue spurs and without orthognathic surgery. All maxillary and mandibular first molars were extracted, and the spaces were closed. Inappropriate retention protocol allowed for relapse ...
Armitage James O JO Department of Medicine, University of Nebraska Medical Center, Omaha, - - 2013
T-cell lymphomas make up approximately 10-15% of lymphoid malignancies. The frequency of these lymphomas varies geographically, with the highest incidence in parts of Asia. The diagnosis of aggressive peripheral T-cell lymphoma (PTCL) is usually made using the WHO classification. The ability of hematopathologists to reproducibly diagnosis aggressive PTCL is lower ...
Lanzafame Raymond J RJ Raymond J. Lanzafame, MD PLLC, Rochester, New - - 2013
Low level laser therapy (LLLT) has been used to promote hair growth. A double-blind randomized controlled trial was undertaken to define the safety and physiologic effects of LLLT on males with androgenic alopecia. Forty-four males (18-48 yo, Fitzpatrick I-IV, Hamilton-Norwood IIa-V) were recruited. A transition zone scalp site was selected; ...
Torres-Lugo Madeline M Department of Chemical Engineering, University of Puerto Rico, Mayaguez Campus, PO BOX 9000, Mayaguez, PR 00681, Puerto Rico. - - 2013
Clinical studies have demonstrated the effectiveness of hyperthermia as an adjuvant for chemotherapy and radiotherapy. However, significant clinical challenges have been encountered, such as a broader spectrum of toxicity, lack of patient tolerance, temperature control and significant invasiveness. Hyperthermia induced by magnetic nanoparticles in high-frequency oscillating magnetic fields, commonly termed ...
Verbalis Joseph G JG Georgetown University Medical Center, Washington, DC. Electronic address: - - 2013
Hyponatremia is a serious, but often overlooked, electrolyte imbalance that has been independently associated with a wide range of deleterious changes involving many different body systems. Untreated acute hyponatremia can cause substantial morbidity and mortality as a result of osmotically induced cerebral edema, and excessively rapid correction of chronic hyponatremia ...
Kandasamy Sanjivan S Clinical associate professor, Department of Orthodontics, School of Dentistry, University of Western Australia, Nedlands, Western Australia, Australia; adjunct assistant professor, Center for Advanced Dental Education, Saint Louis University, St Louis, Mo. Electronic address: - - 2013
In this study, we evaluated the reliability and validity of 3 bite registrations in relation to condylar position in the glenoid fossae using magnetic resonance imaging in a symptom-free population. Nineteen subjects, 14 men and 5 women (ages, 20-39 years) without temporomandibular disorders were examined. Three bite registrations were taken ...
Sartini Claudio C Regional Center for Urban Areas, ARPA Emilia-Romagna, Via Rocchi 19, 40138 Bologna, Italy. - - 2013
The aim of this study was to investigate the influence of an urban area on ultrafine particle (UFP) concentration in nearby surrounding areas. We assessed how downwind and upwind conditions affect the UFP concentration at a site placed a few kilometres from the city border. Secondarily, we investigated the relationship ...
Schmitt F A FA Departments of Neurology, Psychiatry, Behavioral Science, and Psychology, Sanders-Brown Center on Aging/Alzheimer's Disease Center, Lexington, KY, - - 2013
The Severe Impairment Battery (SIB), a reliable cognitive measure for evaluating treatment response in advanced Alzheimer's disease (AD), takes approximately 20 min to administer. A recently derived 8-item version of the SIB - the SIB-8 - which takes about 3 min to administer, may represent a more convenient tool for ...
Cabrini Marcelo R MR Department of Urology, Johns Hopkins Medical Institutions, Baltimore, MD; Department of Surgery, Division of Urology, Sao Paulo Federal University, Sao Paulo, Brazil; CAPES Foundation, Ministry of Education of Brazil, Brasilia, - - 2013
To characterize transforming growth factor beta 1 (TGFβ1) and related signaling pathway proteins in a large cohort of human penile tissue (HPT) samples. HPT was collected from patients undergoing penile prosthesis implantation for erectile dysfunction (ED) and divided into the following 2 groups: postradical prostatectomy ED (RP-ED; n = 57) and ...
Ortega Mario - - 2013
The human immunodeficiency virus (HIV) has multiple genetic clades with varying prevalence throughout the world. Both HIV clade C (HIV-C) and HIV clade B (HIV-B) can cause cognitive impairment, but it is unclear if these clades are characterized by similar patterns of brain dysfunction. We examined brain volumetrics and neuropsychological ...
Morris Sheldon R - - 2013
HIV coreceptor usage of CXCR4 (X4) is associated with decreased CD4+ T-cell counts and accelerated disease progression, but the role of X4 tropism in HIV-associated neurocognitive disorders (HAND) has not previously been described. This longitudinal study evaluated data on 197 visits from 72 recently HIV-infected persons who had undergone up ...
Jacobs Michelle M - - 2013
It has been postulated that drugs of abuse act synergistically with HIV, leading to increased neurotoxicity and neurocognitive impairment. The CNS impacts of HIV and drug use converge on the mesocorticolimbic dopamine (DA) system, which contains two main receptor subtypes: dopamine receptors 1 (DRD1) and 2 (DRD2). DRD1 and DRD2 ...
Xia Zeyang Z Associate professor, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences and Chinese University of Hong Kong, Hong Kong, - - 2013
The orthodontic load system, especially ideal moment-to-force ratios, is the commonly used design parameter of segmental T-loops for canine retraction. However, the load system, including moment-to-force ratios, can be affected by the changes in canine angulations and interbracket distances. We hypothesized that clinical changes in canine position and angulation during ...
Wisniewski J A JA Asthma and Allergic Diseases Center, University of Virginia Health System, Charlottesville, VA, - - 2013
Atopic dermatitis (AD) is common in children; however, persistence of AD with or without asthma is less common. Longitudinal studies remain limited in their ability to characterize how IgE antibody responses evolve in AD, and their relationship with asthma. To use a cross-sectional study design of children with active AD ...
Siracusa Mark C MC Department of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pa; Institute for Immunology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, - - 2013
Basophils were discovered by Paul Ehrlich in 1879 and represent the least abundant granulocyte population in mammals. The relative rarity of basophils and their phenotypic similarities with mast cells resulted in this cell lineage being historically overlooked, both clinically and experimentally. However, recent studies in human subjects and murine systems ...
Feaster Daniel J DJ 1Department of Public Health Sciences, University of Miami, Miami, FL, - - 2013
The prevalence of HIV infection among male prison inmates is significantly higher than in the U.S. population. Adequate planning to ensure continued medication adherence and continuity of care after release is important for this population. This study describes the prerelease characteristics of 162 incarcerated HIV-positive men (40 from jails and ...
Gershuni Victoria V Department of Surgery and Institute for Minimally Invasive Surgery, Washington University School of Medicine, St. Louis, - - 2013
We evaluated suturing skills performance and retention in senior medical students (MS4) at the beginning of their fourth year and 7 months later. MS4 students entering a surgery specialty were randomized to a proficiency-based suturing/knot-tying curriculum at the beginning of fourth year (Intervention, n = 11) versus no training (Control, ...
Ballard Elizabeth D ED From the *Department of Psychiatry and Behavioral Sciences, Johns Hopkins School of Medicine, Baltimore; and †National Institute of Mental Health, NIH, Bethesda, MD; ‡Department of Psychology, The Catholic University of America; and §Division of Emergency Medicine, Children's National Medical Center, Washington, - - 2013
Although validated suicide screening tools exist for use among children and adolescents presenting to emergency departments (EDs), the associations between screening positive for suicide risk and immediate psychiatric hospital admission or subsequent ED use, stratified by age, have not been examined. This is a retrospective cohort study of a consecutive ...
Bekmezian Arpi A From the Departments of *Pediatrics, †Emergency Medicine, ‡School of Dentistry, and §Department of Medicine, University of California, San Francisco, San Francisco, - - 2013
This study aimed to identify factors associated with delayed or omission of indicated steroids for children seen in the emergency department (ED) for moderate-to-severe asthma exacerbation. This was a retrospective study of pediatric (age ≤ 21 years) patients treated in a general academic ED from January 2006 to September 2011 ...
Fischer John P JP Philadelphia, Pa. From the Division of Plastic Surgery, Hospital of the University of - - 2013
The authors assess the risk and safety profiles of both implant and autologous breast reconstructions in the morbidly obese population using the National Surgical Quality Improvement Program data sets. The authors reviewed the 2005 to 2010 National Surgical Quality Improvement Program databases, identifying encounters for Current Procedural Terminology codes including ...
Yang Chao C Shanghai, People's Republic of China From the Department of Plastic Surgery, Changhai Hospital, Second Military Medical - - 2013
The tear trough and palpebromalar groove are of increasing interest to plastic surgeons, but their mechanisms of formation remain unclear. This study evaluated the anatomical foundation for tear trough and palpebromalar groove. Sagittal dissection and layered dissection were performed on 20 elderly cadaveric hemifaces with obvious tear troughs and palpebromalar ...
Donfrancesco Andrea A Stockholm, Sweden From - - 2013
Breast augmentation is one of the most commonly performed operations. Three-dimensional outcome simulation can be used to predict and demonstrate for the patient what the planned operation aims to achieve in terms of size and shape. However, there are still few studies in the literature that look at how close ...
Balagué Nicolas N Geneva, Switzerland From the Plastic, Reconstructive and Aesthetic Surgery Department, the General Surgery Department, and the Division of Clinical Epidemiology, Center of Clinical Research, University Hospitals of Geneva, University of - - 2013
The positive impact of Roux-en-Y gastric bypass on weight, comorbidities, and health-related quality of life is well documented. However, 50 percent of patients regain some of the lost weight after 2 years with Roux-en-Y gastric bypass and present a mean weight regain of 10 to 15 percent after several years, ...
Mirastschijski Ursula U Bremen, Hannover, and Essen, Germany From the Department of Plastic, Reconstructive, and Aesthetic Surgery, Klinikum Bremen-Mitte, Center for Biomolecular Interactions Bremen and Collaboration Center Medicine, University of Bremen; the Department of Plastic, Hand, and Reconstructive Surgery, Hannover Medical School; and the Division of Plastic and Reconstructive Surgery, Clinic for Senologie/Breast Center, Kliniken Essen-Mitte Evang. Huyssens Stiftung/Knappschaft - - 2013
Xenogenous dermal matrices are used for hernia repair and breast reconstruction. Full-thickness skin replacement is needed after burn or degloving injuries with exposure of tendons or bones. The authors used a human skin organ culture model to study whether porcine reconstructive tissue matrix (Strattice) is effective as a dermal tissue ...
Isomura Emiko T ET Suita and Yao, Osaka, Japan From the First Department of Oral and Maxillofacial Surgery, Osaka University, Graduate School of Dentistry; and the Department of Oral and Maxillofacial Surgery, Yao Municipal - - 2013
Bifocal distraction osteogenesis has been shown to be a reliable method for reconstructing missing bone segments. However, there are no reports regarding inferior alveolar nerve regeneration during bifocal distraction. In the present study, the authors evaluated the function of inferior alveolar nerve regenerated by bifocal distraction after segmental resection in ...
Stahl Stéphane S Tübingen and Stuttgart, Germany From the Department of Plastic, Hand and Reconstructive Surgery, Burn Center, BG-Trauma Center, the Institute for Clinical Epidemiology and Applied Biostatistics, and the University Department of Radiology, Eberhard-Karls-University Tübingen; and the Department for Plastic Surgery, Marienhospital - - 2013
Negative ulnar variance has been associated with Kienböck disease, both supporting a causal link and providing a basis for therapeutic recommendations. The aim of this study was to determine whether there is a causal relationship between Kienböck disease and negative ulnar variance. The causal relationship between Kienböck disease and negative ...
Larson John V JV East Lansing and Ann Arbor, Mich. From the College of Human Medicine, Michigan State University; and the Section of Plastic Surgery, Department of Surgery, University of - - 2013
Little knowledge exists concerning replantation following traumatic major upper extremity amputation. This study characterizes the injury patterns and outcomes of patients suffering major upper extremity amputation and ascertains clinical factors associated with the decision to attempt replantation. A retrospective cohort study was conducted on patients treated at a Level I ...
Shetye Pradip R PR New York, N.Y.; and Boston, Mass. From the Institute of Reconstructive Plastic Surgery, New York University Medical Center, and Brigham and Women's - - 2013
The purpose of this study was to characterize soft-tissue profile changes following Le Fort III (midface) distraction in growing patients with syndromic craniosynostosis. The cohort consisted of 20 syndromic patients who underwent Le Fort III osteotomy with midface advancement using a rigid external distraction device. The mean age at surgery ...
Lee Justine C JC Chicago, Ill. From the Section of Plastic and Reconstructive Surgery, Department of Surgery, University of Chicago Medical - - 2013
Composite cranial defects in the setting of infection, irradiation, or cerebrospinal fluid leak present a significant risk for devastating neurologic sequelae. Such defects require soft-tissue coverage and skeletal reconstruction that can withstand the hostile environment of a precarious wound. Patients with high-risk composite cranial defects treated with free flap reconstruction ...
Quigley Meghan A MA Pittsburgh, Pa. From the Department of Plastic Surgery, University of Pittsburgh School of - - 2013
Among the most common complications associated with abdominal organ transplantation are issues with abdominal wall closure. This difficulty, along with the recent rise in the use of vascularized composite allotransplantation, has led surgeons to the notion of abdominal wall transplantation. The authors have developed a novel surgical model for a ...
Akita Shinsuke S Chiba and Nankoku, Japan From the Department of Plastic and Reconstructive Surgery, Chiba Cancer Center; the Department of Plastic, Reconstructive and Aesthetic Surgery, Chiba University, Faculty of Medicine; and the Department of Plastic and Reconstructive Surgery, Kochi Medical School - - 2013
Subcutaneous ecchymosis caused by venous reflux is a preventable complication following lymphaticovenular anastomosis. The authors developed a series of operative procedures to prevent venous reflux. This is probably the first report on valvuloplasty for small subcutaneous veins (diameter, <1 mm). A total of 165 anastomoses in 39 limbs were operated ...
Levine Steven M SM New York, N.Y; Charleston, S.C.; and New Orleans, La. From the Institute of Reconstructive Plastic Surgery, New York University Langone Medical Center; Medical University of South Carolina; Tulane University Health Science Center; and Louisiana State University School of - - 2013
Recent evolutions of oncologic breast surgery and reconstruction now allow surgeons to offer the appropriate patients a single-stage, autologous tissue reconstruction with the least donor-site morbidity. The authors present their series of buried free flaps in nipple-sparing mastectomies as proof of concept, and to explore indications, techniques, and early outcomes ...
Fiaschetti Valeria V Rome, Italy From the Department of Diagnostic Imaging, Molecular Imaging, Interventional Radiology, and Radiation Therapy, University Hospital Tor Vergata, and the Department of Plastic and Reconstructive Surgery, Policlinico Casilino, University Tor - - 2013
Breast lipofilling is a fairly simple and safe procedure if it is performed by experienced surgeons. The authors evaluated the radiologic findings from 24 breasts (15 women) subjected to a lipofilling procedure (two sessions) for corrective surgery or cosmetic reasons. Mammography, ultrasound, and magnetic resonance imaging were performed before the ...
Park Dae Hwan DH Daegu and Ulsan, Republic of Korea From the Department of Plastic and Reconstructive Surgery, College of Medicine, Catholic University of Daegu; and the Department of Plastic and Reconstructive Surgery, Dong Kang General - - 2013
In ptosis surgery, not addressing the epicanthal fold leaves a persistent rounded nasal scleral triangle, which blunts the effect of ptosis repair and leads to patient dissatisfaction. To achieve satisfactory results, epicanthoplasty is usually performed with ptosis correction. Furthermore, surgeons usually choose epicanthoplasty methods based on personal preference, and no ...
Camenisch Colette C CC Stockholm and Solna, Sweden From Akademikliniken; Department of Radiology, Sophiahemmet Hospital Stockholm; and Karolinska University - - 2013
Macrolane is a biocompatible, biodegradable, injectable stabilized hyaluronic acid-based gel of nonanimal origin manufactured using the nonanimal stabilized hyaluronic acid technology. This was a substudy to evaluate localization, displacement, and degradation of the gel when used for volume restoration and shaping of the buttocks. Subjects aged 20 years or older ...
Hu Ching-Hsuan CH Taoyuan and Taichung, Taiwan From the Center for Vascularized Composite Allotransplantation, Department of Plastic and Reconstructive Surgery, Chang Gung Memorial Hospital, Chang Gung Medical College and Chang Gung University; the Department of Public Health, Chung Shan Medical University; and the Department of Family and Community Medicine, Chung Shan Medical University - - 2013
Vascularized composite allotransplantation is an emerging field of transplantation that provides a potential treatment for complex tissue defects after traumatic loss or tumor resection and for the repair of congenital abnormalities. However, vascularized composite allotransplantation recipients have suffered from acute and chronic graft rejection that is associated with oxidative stress. ...
Felice Peter A PA Ann Arbor, Mich.; and Columbia, S.C. From the Craniofacial Research Laboratory, Plastic Surgery Section, University of Michigan; and the Department of Surgery, University of South Carolina School of - - 2013
The authors' laboratory has previously demonstrated that deferoxamine promotes angiogenesis and bone repair in the setting of radiation therapy coupled with distraction osteogenesis. However, clinically relevant effects of deferoxamine administration on union rate and micro-computed tomographic and biomechanical parameters are unknown. The authors posit that administration of deferoxamine will increase ...
Bloom Jacob M P JM Rochester, N.Y. From the Division of Plastic Surgery and the Department of Orthopedics, University of Rochester Medical - - 2013
The mallet finger is a frequently encountered fingertip injury that leads to extensor lag of the distal phalanx. Classification systems stratify these injuries as ranging from soft-tissue disruption of the extensor mechanism alone to those that have articular involvement and volar subluxation. The management of mallet finger injuries varies based ...
Schmitt Taliah T Palo Alto, Calif. From the Division of Plastic and Reconstructive Surgery, Stanford University Medical - - 2013
Tissue-engineered human flexor tendons may be an option to aid in reconstruction of complex upper extremity injuries with significant tendon loss. The authors hypothesize that human adipose-derived stem cells remain viable following reseeding on human tendon scaffolds in vivo and aid in graft integration. Decellularized human flexor tendons harvested from ...
Caterson E J EJ New York, N.Y. From the Institute of Reconstructive Plastic Surgery, New York University Langone Medical - - 2013
The classic Le Fort III procedure was recommended in syndromic craniosynostotic children to reduce exorbitism, improve airway function, and decrease dysmorphism. This study reports on a cohort of syndromic craniosynostosis patients who have undergone early primary subcranial (classic Tessier) Le Fort III advancement and who have been followed longitudinally through ...
Seruya Mitchel M Melbourne, Victoria, Australia From the Department of Plastic and Maxillofacial Surgery and the Department of Neurosurgery, Royal Children's Hospital Melbourne; and the Department of Paediatrics, University of - - 2013
Total vault reconstruction addresses all phenotypic aspects of scaphocephaly. The clinical implications of remodeling across open cranial sutures, however, remain unclear. The purpose of this study was to assess patency of unaffected sutures following total vault remodeling for isolated sagittal synostosis. The authors reviewed routine postoperative computed tomographic scans of ...
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