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Tárnoki Adám Domonkos - - 2013
Twin studies play a role in examining the contribution of genetic variations and environmental factors responsible for the determination of phenotypic variables and of genetic linkage between genotypes. Hungarian twin studies, supported by three twin registries (among them two twin-database), date back to 1970s. Studies mainly focused on various congenital ...
Lee Gillian H M - - 2013
This study aimed to explore the preferred treatment for pre-school children with caries of different severities in primary teeth among general dental practitioners (GDPs) and specialists in paediatric dentistry (PDs) in Hong Kong, and to determine the difference in practice patterns between the groups. A random sample of 476 GDPs ...
Kakuta Erika - - 2013
The burden of health-care costs relative to gross domestic product in Japan is increasing. A large percentage (7.6% in 2009) of the Japanese gross domestic product has been spent on health care, and this percentage has been increasing annually. Soaring health-care costs have been recognised as a serious social problem. ...
Komiya Tatsuhiko - - 2013
Reform of the Japanese postgraduate residency program has dramatically influenced the recruitment system. Because shortage of young cardiac surgeons is anticipated, an effective program for residents who want to become cardiac surgeons must be established at an earlier stage in surgical training. A 3-year cardiac surgery residency curriculum was developed ...
Micheels Patrick - - 2013
With the proliferation of dermal fillers in the aesthetic workplace have come instructions from various manufacturers regarding dermal placement. Determination of injection needle location in the dermis has in large part been based on physician expertise, product and needle familiarity, and patient-specific skin characteristics. An understanding of the precise depth ...
Downie Jeanine B - - 2013
Although the use of the hyaluronic acid with cohesive polydensified matrix hyaluronic acid has been well explored in subjects with lighter skin (i.e., Fitzpatrick skin types I, II, and III), further exploration in subjects with Fitzpatrick skin types IV, V, and IV is warranted. The primary purpose of the study ...
Lorenc Z Paul - - 2013
Belotero Balance is a novel highly cross-linked hyaluronic acid that uses cohesive polydensified matrix technology to achieve cohesive gel; improved adaptation by the dermis; and a soft, smooth fill. Several studies have now compared Belotero Balance to bovine collagen and other hyaluronic acids. Two pivotal studies demonstrated the noninferiority and ...
Flynn Timothy Corcoran - - 2013
In this study, the authors sought to determine the molecular weight distribution of three hyaluronic acids-Belotero Balance, Restylane, and Juvéderm Ultra-and their rates of degradation following exposure to hyaluronidase. Lot consistency of Belotero Balance also was analyzed. Three lots of Belotero Balance were analyzed using liquid chromatography techniques. The product ...
Hazell Alan S - - 2013
Thiamine deficiency (TD) leads to Wernicke's encephalopathy (WE), in which focal histological lesions occur in periventricular areas of the brain. Recently, impaired neurogenesis has been reported in the hippocampus during the dietary form of TD, and in pyrithiamine-induced TD (PTD), a well-characterized model of WE. To further characterize the consequences ...
Yamalik Nermin - - 2013
As National Dental Associations and dental faculties can be considered as the two major institutions representing national organised dentistry, their further extended collaboration is crucial in responding to the many global oral health matters and issues. The main aim of the present study is to analyse the nature and extent ...
Wills A K - - 2013
It has been suggested that maternal vitamin D status in pregnancy influences the risk of asthma and atopy in the offspring. The epidemiological evidence to support these claims is conflicting and may reflect chance findings and differences in how vitamin D was assessed. To examine the association between blood total ...
Sundaram Hema H Rockville, Md.; Fairfax, Va.; and Milan, Italy From private - - 2013
The purpose of this study was to present new rheologic data for hyaluronic acid filler products, correlate them with recent tissue integration studies, and provide a scientific rationale for selecting appropriate products for volume replacement within different tissue levels and anatomical zones. A brief overview of the methodology of filler ...
Huh Ahrin A Private practice, Teaneck, - - 2013
Genetic influences on the development of malocclusion include heritable effects on both masticatory muscles and jaw skeletal morphology. Beyond genetic variations, however, the characteristics of muscle and bone are also influenced by epigenetic mechanisms that produce differences in gene expression. We studied 2 enzymes known to change gene expressions through ...
Hu Ching-Hsuan CH Taoyuan and Taichung, Taiwan From the Center for Vascularized Composite Allotransplantation, Department of Plastic and Reconstructive Surgery, Chang Gung Memorial Hospital, Chang Gung Medical College and Chang Gung University; the Department of Public Health, Chung Shan Medical University; and the Department of Family and Community Medicine, Chung Shan Medical University - - 2013
Vascularized composite allotransplantation is an emerging field of transplantation that provides a potential treatment for complex tissue defects after traumatic loss or tumor resection and for the repair of congenital abnormalities. However, vascularized composite allotransplantation recipients have suffered from acute and chronic graft rejection that is associated with oxidative stress. ...
Gershuni Victoria V Department of Surgery and Institute for Minimally Invasive Surgery, Washington University School of Medicine, St. Louis, - - 2013
We evaluated suturing skills performance and retention in senior medical students (MS4) at the beginning of their fourth year and 7 months later. MS4 students entering a surgery specialty were randomized to a proficiency-based suturing/knot-tying curriculum at the beginning of fourth year (Intervention, n = 11) versus no training (Control, ...
Krishnan Vinod V Professor, Department of Orthodontics, Sri Sankara Dental College, Trivandrum, Kerala, India. Electronic address: - - 2013
Publishing a scientific article in a journal with a high impact factor and a good reputation is considered prestigious among one's peer group and an essential achievement for career progression. In the drive to get their work published, researchers can forget, either intentionally or unintentionally, the ethics that should be ...
Teitelbaum Ezra N EN Department of Surgery, Northwestern University Feinberg School of Medicine, Chicago, - - 2013
Peroral esophageal myotomy (POEM) differs from laparoscopic Heller myotomy (LHM) in that only the circular muscle layer of the esophagus is divided, the hiatus is not mobilized, and an antireflux procedure is not performed. The effect of these differences on anatomic and functional outcomes is unknown. Patients who underwent LHM ...
Cherenfant Jovenel J NorthShore University HealthSystems, Evanston, IL. Electronic address: - - 2013
The biologic potential of nonfunctioning pancreatic neuroendocrine tumors (PNETs) is highly variable and difficult to predict before resection. This study was conducted to identify clinical and pathologic factors associated with malignant behavior and death in patients diagnosed with PNETs. We used International Classification of Diseases 9th edition codes to identify ...
Donfrancesco Andrea A Stockholm, Sweden From - - 2013
Breast augmentation is one of the most commonly performed operations. Three-dimensional outcome simulation can be used to predict and demonstrate for the patient what the planned operation aims to achieve in terms of size and shape. However, there are still few studies in the literature that look at how close ...
Balagué Nicolas N Geneva, Switzerland From the Plastic, Reconstructive and Aesthetic Surgery Department, the General Surgery Department, and the Division of Clinical Epidemiology, Center of Clinical Research, University Hospitals of Geneva, University of - - 2013
The positive impact of Roux-en-Y gastric bypass on weight, comorbidities, and health-related quality of life is well documented. However, 50 percent of patients regain some of the lost weight after 2 years with Roux-en-Y gastric bypass and present a mean weight regain of 10 to 15 percent after several years, ...
Athanasiadis Yannis Y From the Moorfields Eye Hospital NHS Foundation Trust (Athanasiadis, Nithyanandarajah, Trivedy, Bishop, A. Sharma) and the Bedford School (B. Sharma), Bedford, United - - 2013
We describe a simple technique to create a peripheral surgical iridotomy using a microvitreoretinal blade. The blade passes perpendicular to the iris dilator fibers to create a permanent opening. No author has a financial or proprietary interest in any material or method mentioned.
Wilson Gregory C GC Department of Surgery, University of Cincinnati Pancreatic Disease Center, University of Cincinnati College of Medicine, Cincinnati, - - 2013
This study aims to review surgical outcomes of pediatric patients undergoing total pancreatectomy with islet cell autotransplantation (TP/IAT) for the treatment of chronic pancreatitis (CP). All pediatric patients (≤18 years old) undergoing TP/IAT over a 10-year period (December 2002-June 2012) were identified for inclusion in a single-center, observational cohort study. ...
Cabrini Marcelo R MR Department of Urology, Johns Hopkins Medical Institutions, Baltimore, MD; Department of Surgery, Division of Urology, Sao Paulo Federal University, Sao Paulo, Brazil; CAPES Foundation, Ministry of Education of Brazil, Brasilia, - - 2013
To characterize transforming growth factor beta 1 (TGFβ1) and related signaling pathway proteins in a large cohort of human penile tissue (HPT) samples. HPT was collected from patients undergoing penile prosthesis implantation for erectile dysfunction (ED) and divided into the following 2 groups: postradical prostatectomy ED (RP-ED; n = 57) and ...
Valenzuela G A GA Wayne State University, 10000 Telegraph Road, Taylor, Michigan 48124, - - 2013
The outcome of high tibial osteotomy (HTO) deteriorates with time, and additional procedures may be required. The aim of this study was to compare the clinical and radiological outcomes between unicompartmental knee replacement (UKR) and total knee replacement (TKR) after HTO as well as after primary UKR. A total of ...
Schmitt F A FA Departments of Neurology, Psychiatry, Behavioral Science, and Psychology, Sanders-Brown Center on Aging/Alzheimer's Disease Center, Lexington, KY, - - 2013
The Severe Impairment Battery (SIB), a reliable cognitive measure for evaluating treatment response in advanced Alzheimer's disease (AD), takes approximately 20 min to administer. A recently derived 8-item version of the SIB - the SIB-8 - which takes about 3 min to administer, may represent a more convenient tool for ...
Kirby M M The Centre for Research in Primary and Community Care (CRIPACC), University of Hertfordshire, Hatfield, Herts, - - 2013
To compare efficacy and tolerability between 100-mg and 50-mg sildenafil doses in five double-blind, placebo-controlled (DBPC) fixed-dose studies. Doses were compared for the change (baseline to end of 8-12 weeks of DBPC treatment) in score on the Erectile Function (EF) domain of the International Index of Erectile Function (IIEF; from ...
McDaniel Jarred M JM Cleveland, Ohio; and Chicago, Ill. From the Department of Plastic Surgery, Case Western Reserve University; and the Division of Plastic Surgery, Lurie Children's Hospital of Northwestern University Feinberg School of - - 2013
Secondary cleft nasal deformity in children of primary school age can result in permanent impact to a child's self-esteem. The ideal technique and timing of addressing the deformity remain controversial, as harvest of septal cartilage affects nasal growth and limits future options. Fifty-three patients underwent secondary cleft nasoplasty with resorbable ...
Fiaschetti Valeria V Rome, Italy From the Department of Diagnostic Imaging, Molecular Imaging, Interventional Radiology, and Radiation Therapy, University Hospital Tor Vergata, and the Department of Plastic and Reconstructive Surgery, Policlinico Casilino, University Tor - - 2013
Breast lipofilling is a fairly simple and safe procedure if it is performed by experienced surgeons. The authors evaluated the radiologic findings from 24 breasts (15 women) subjected to a lipofilling procedure (two sessions) for corrective surgery or cosmetic reasons. Mammography, ultrasound, and magnetic resonance imaging were performed before the ...
Morris Sheldon R - - 2013
HIV coreceptor usage of CXCR4 (X4) is associated with decreased CD4+ T-cell counts and accelerated disease progression, but the role of X4 tropism in HIV-associated neurocognitive disorders (HAND) has not previously been described. This longitudinal study evaluated data on 197 visits from 72 recently HIV-infected persons who had undergone up ...
Xia Zeyang Z Associate professor, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences and Chinese University of Hong Kong, Hong Kong, - - 2013
The orthodontic load system, especially ideal moment-to-force ratios, is the commonly used design parameter of segmental T-loops for canine retraction. However, the load system, including moment-to-force ratios, can be affected by the changes in canine angulations and interbracket distances. We hypothesized that clinical changes in canine position and angulation during ...
Mali Prashant P Department of Genetics, Harvard Medical School, Boston, Massachusetts, - - 2013
RNA-guided Cas9 nucleases derived from clustered regularly interspaced short palindromic repeats (CRISPR)-Cas systems have dramatically transformed our ability to edit the genomes of diverse organisms. We believe tools and techniques based on Cas9, a single unifying factor capable of colocalizing RNA, DNA and protein, will grant unprecedented control over cellular ...
Michels Karin B KB 1] Obstetrics and Gynecology Epidemiology Center, Department of Obstetrics and Gynecology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA. [2] Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts, - - 2013
Epigenome-wide association studies (EWAS) hold promise for the detection of new regulatory mechanisms that may be susceptible to modification by environmental and lifestyle factors affecting susceptibility to disease. Epigenome-wide screening methods cover an increasing number of CpG sites, but the complexity of the data poses a challenge to separating robust ...
Siracusa Mark C MC Department of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pa; Institute for Immunology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, - - 2013
Basophils were discovered by Paul Ehrlich in 1879 and represent the least abundant granulocyte population in mammals. The relative rarity of basophils and their phenotypic similarities with mast cells resulted in this cell lineage being historically overlooked, both clinically and experimentally. However, recent studies in human subjects and murine systems ...
Fischer John P JP Philadelphia, Pa. From the Division of Plastic Surgery, Hospital of the University of - - 2013
The authors assess the risk and safety profiles of both implant and autologous breast reconstructions in the morbidly obese population using the National Surgical Quality Improvement Program data sets. The authors reviewed the 2005 to 2010 National Surgical Quality Improvement Program databases, identifying encounters for Current Procedural Terminology codes including ...
Bloom Jacob M P JM Rochester, N.Y. From the Division of Plastic Surgery and the Department of Orthopedics, University of Rochester Medical - - 2013
The mallet finger is a frequently encountered fingertip injury that leads to extensor lag of the distal phalanx. Classification systems stratify these injuries as ranging from soft-tissue disruption of the extensor mechanism alone to those that have articular involvement and volar subluxation. The management of mallet finger injuries varies based ...
Bosio Jose A JA Assistant professor, Department of Developmental Sciences/Orthodontics, School of Dentistry, Marquette University, Milwaukee, Wis. Electronic address: - - 2013
An 8-mm anterior and posterior open bite caused by a tongue rest posture habit was closed in a 25-year-old man by means of mandibular soldered tongue spurs and without orthognathic surgery. All maxillary and mandibular first molars were extracted, and the spaces were closed. Inappropriate retention protocol allowed for relapse ...
Armitage James O JO Department of Medicine, University of Nebraska Medical Center, Omaha, - - 2013
T-cell lymphomas make up approximately 10-15% of lymphoid malignancies. The frequency of these lymphomas varies geographically, with the highest incidence in parts of Asia. The diagnosis of aggressive peripheral T-cell lymphoma (PTCL) is usually made using the WHO classification. The ability of hematopathologists to reproducibly diagnosis aggressive PTCL is lower ...
Kandasamy Sanjivan S Clinical associate professor, Department of Orthodontics, School of Dentistry, University of Western Australia, Nedlands, Western Australia, Australia; adjunct assistant professor, Center for Advanced Dental Education, Saint Louis University, St Louis, Mo. Electronic address: - - 2013
In this study, we evaluated the reliability and validity of 3 bite registrations in relation to condylar position in the glenoid fossae using magnetic resonance imaging in a symptom-free population. Nineteen subjects, 14 men and 5 women (ages, 20-39 years) without temporomandibular disorders were examined. Three bite registrations were taken ...
Feaster Daniel J DJ 1Department of Public Health Sciences, University of Miami, Miami, FL, - - 2013
The prevalence of HIV infection among male prison inmates is significantly higher than in the U.S. population. Adequate planning to ensure continued medication adherence and continuity of care after release is important for this population. This study describes the prerelease characteristics of 162 incarcerated HIV-positive men (40 from jails and ...
Kelly Elizabeth M EM Blue Cross Blue Shield of Michigan/University of Michigan Health Systems, 600 E. Lafayette, Mail Code 512C, Detroit, MI 48226., USA E-mail: - - 2013
Obesity may lead to the development of multiple chronic disease states, including hypertension, dyslipidemia, and type 2 diabetes mellitus. Over a half billion adults worldwide are affected by obesity, and more than two-thirds of adults are either obese or overweight in the United States. Diet and exercise have been the ...
Zhan Chun - - 2013
Dissolution and migration of manganese from cathode lead to severe capacity fading of lithium manganate-carbon cells. Overcoming this major problem requires a better understanding of the mechanisms of manganese dissolution, migration and deposition. Here we apply a variety of advanced analytical methods to study lithium manganate cathodes that are cycled ...
Legg David A - - 2013
The relationships of major arthropod clades have long been contentious, but refinements in molecular phylogenetics underpin an emerging consensus. Nevertheless, molecular phylogenies have recovered topologies that morphological phylogenies have not, including the placement of hexapods within a paraphyletic Crustacea, and an alliance between myriapods and chelicerates. Here we show enhanced ...
Gody Guillaume - - 2013
A long-standing challenge in polymer chemistry has been to prepare synthetic polymers with not only well-defined molecular weight, but also precisely controlled microstructure in terms of the distribution of monomeric units along the chain. Here we describe a simple and scalable method that enables the synthesis of sequence-controlled multiblock copolymers ...
Jacques Simon D M - - 2013
An emerging theme of modern composites and devices is the coupling of nanostructural properties of materials with their targeted arrangement at the microscale. Of the imaging techniques developed that provide insight into such designer materials and devices, those based on diffraction are particularly useful. However, to date, these have been ...
Tian Yancong - - 2013
According to transition state theory, the rate of a reaction that traverses multiple energy barriers is determined by the least stable (rate-determining) transition state. The preceding ('inner') energy barriers are kinetically 'invisible' but mechanistically significant. Here we show experimentally and computationally that the reduction rate of organic disulphides by phosphines ...
Liu Dazhi - - 2013
Small-angle neutron scattering (SANS) is the most significant neutron technique in terms of impact on science and engineering. However, the basic design of SANS facilities has not changed since the technique's inception about 40 years ago, as all SANS instruments, save a few, are still designed as pinhole cameras. Here ...
Adera Solomon - - 2013
Controlling wettability by varying surface chemistry and roughness or by applying external stimuli is of interest for a wide range of applications including microfluidics, drag reduction, self-cleaning, water harvesting, anti-corrosion, anti-fogging, anti-icing and thermal management. It has been well known that droplets on textured hydrophilic, that is superhydrophilic, surfaces form ...
Polley Daniel B - - 2013
Early binaural experience can recalibrate central auditory circuits that support spatial hearing. However, it is not known how binaural integration matures shortly after hearing onset or whether various developmental stages are differentially impacted by disruptions of normal binaural experience. Here we induce a brief, reversible unilateral conductive hearing loss (CHL) ...
Son Hyewon - - 2013
Ultrafast two-dimensional infrared (2DIR) spectroscopy was used to study H-bond exchange dynamics in aqueous NaPF6 solutions. Interestingly, there are two spectrally distinct hydrogen-bond (H-bond) configurations in aqueous NaPF6 solutions; water molecules that are H-bonded to PF6(-) ion (ODA) or other water molecules (ODW). These two spectrally distinct subsets of water ...
Patterson Dustin P - - 2013
Here we report the use of a self-assembling protein cage to sequester and solubilize recombinant proteins which are usually trafficked to insoluble inclusion bodies. Our results suggest that protein cages can be used as novel vehicles to rescue and produce soluble proteins that are otherwise difficult to obtain using conventional ...
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