Search Results
Results 301 - 350 of 4329
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Modery-Pawlowski Christa L - - 2013
Platelets are megakaryocyte-derived anucleated cells found in the blood. They are mainly responsible for rendering hemostasis or clotting to prevent bleeding complications. Decreased platelet numbers or deficiencies in platelet functions can lead to various acute or chronic bleeding conditions and hemorrhage. On the other hand, dysregulated hyperactivity of the clotting ...
Vetrano Davide Liborio - - 2013
Primordial prevention is essential for reaching cardiovascular (CV) health. This is defined by seven health metrics identified by the American Heart Association. Aim of the present study was to assess prevalence and distribution of these seven CV health metrics within an unselected population. All the 1110 consecutive individuals (mean age ...
Mastropasqua Leonardo - - 2013
To use scanning electron microscopy (SEM) to evaluate capsulorhexis-cut quality obtained during femtosecond laser-assisted cataract surgery at different energy settings and evaluate whether there are differences between this technique and a standard manual technique. Ophthalmology Clinic, Department of Medicine and Science of Ageing, University G. D'Annunzio Chieti-Pescara, Chieti, Italy. Prospective nonrandomized ...
Belenko Steven - - 2013
HIV risk is disproportionately high among incarcerated individuals. Corrections agencies have been slow to implement evidence-based guidelines and interventions for HIV prevention, testing, and treatment. The emerging field of implementation science focuses on organizational interventions to facilitate adoption and implementation of evidence-based practices. A survey of correctional agency partners from ...
Balagué Nicolas N Geneva, Switzerland From the Plastic, Reconstructive and Aesthetic Surgery Department, the General Surgery Department, and the Division of Clinical Epidemiology, Center of Clinical Research, University Hospitals of Geneva, University of - - 2013
The positive impact of Roux-en-Y gastric bypass on weight, comorbidities, and health-related quality of life is well documented. However, 50 percent of patients regain some of the lost weight after 2 years with Roux-en-Y gastric bypass and present a mean weight regain of 10 to 15 percent after several years, ...
Matlack Glenn R - - 2013
Prescribed burning is increasingly being used in the deciduous forests of eastern North America. Recent work suggests that historical fire frequency has been overestimated east of the prairie-woodland transition zone, and its introduction could potentially reduce forest herb and shrub diversity. Fire-history recreations derived from sedimentary charcoal, tree fire scars, ...
Deneve Jeremiah L - - 2013
Cutaneous leiomyosarcoma is primarily a low-grade malignancy that affects elderly male Caucasians. It is a rare dermal-based tumor for which treatment algorithms have been poorly defined. We retrospectively reviewed the use of a median 1-cm margin for resection to treat patients with cutaneous leiomyosarcoma referred for treatment between 2005 and ...
McKay Bailey D - - 2013
The process of discovering species is a fundamental responsibility of systematics. Recently, there has been a growing interest in coalescent-based methods of species delimitation aimed at objectively identifying species early in the divergence process. However, few empirical studies have compared these new methods with character-based approaches for discovering species. In ...
van Biesen Wim - - 2013
Volume status, lean and fat tissue are gaining interest as prognostic predictors in patients on dialysis. Comparative data in peritoneal dialysis (PD) versus haemodialysis (HD) patients are lacking. In a cohort of PD (EuroBCM) and HD (Euclid database) patients, matched for country, gender, age and dialysis vintage, body composition was ...
Schmitt Taliah T Palo Alto, Calif. From the Division of Plastic and Reconstructive Surgery, Stanford University Medical - - 2013
Tissue-engineered human flexor tendons may be an option to aid in reconstruction of complex upper extremity injuries with significant tendon loss. The authors hypothesize that human adipose-derived stem cells remain viable following reseeding on human tendon scaffolds in vivo and aid in graft integration. Decellularized human flexor tendons harvested from ...
Gabbe B J - - 2013
We describe the routine imaging practices of Level 1 trauma centres for patients with severe pelvic ring fractures, and the interobserver reliability of the classification systems of these fractures using plain radiographs and three-dimensional (3D) CT reconstructions. Clinical and imaging data for 187 adult patients (139 men and 48 women, ...
Reikvam H - - 2013
Proliferative capacity of acute myelogenous leukaemia (AML) blasts is important for leukaemogenesis, and we have investigated whether proliferative capacity of primary human AML cells could be used for subclassification of patients. In vitro proliferative capacity of AML cells derived from two independent groups was investigated. Cells were cultured under highly ...
Nho Shane J - - 2013
The purpose of this study was to compare suture anchor placement in the acetabular rim between straight and curved drill guides regarding angle and distance of the suture anchor tip from the articular cartilage during labral refixation. A total of 14 fresh-frozen cadaveric hips underwent arthroscopic labral incision from the ...
Martin Benjamin M - - 2013
The standard treatment of care for melanoma metastatic to the inguinal lymph node basin is lymphadenectomy. However, up to 50% of patients forgo the operation partly due to concerns about morbidity. Videoscopic inguinal lymphadenectomy (VIL) is a minimally invasive technique designed to minimize wound complications while achieving comparable oncological control. ...
Tamura S - - 2013
We investigated differences in the location and mode of labral tears between dysplastic hips and hips with femoroacetabular impingement (FAI). We also investigated the relationship between labral tear and adjacent cartilage damage. We retrospectively studied 72 symptomatic hips (in 68 patients: 19 men and 49 women) with radiological evidence of ...
Macdonald Justin A - - 2013
Nucleotide-binding domain and leucine-rich repeat-containing receptors (NLRs) regulate innate immunity by activating inflammatory responses in a variety of biological systems following the recognition of pathogen- or disease-associated molecular patterns. NLRs are characterized by a central nucleotide-binding and oligomerization (NACHT) domain found in P-loop NTPases. In this review, we detail the ...
Petel Dara - - 2013
Randomized trials have shown no benefit to thoracoscopic decortication over pleural drainage with fibrinolytic installation for pediatric empyema. However, the optimal method of pleural drainage has not been defined. The present study compares outcomes of 8.5-Fr soft pigtail catheters (PC) placed via Seldinger technique with larger caliber, stiff chest tubes ...
Teitelbaum Ezra N EN Department of Surgery, Northwestern University Feinberg School of Medicine, Chicago, - - 2013
Peroral esophageal myotomy (POEM) differs from laparoscopic Heller myotomy (LHM) in that only the circular muscle layer of the esophagus is divided, the hiatus is not mobilized, and an antireflux procedure is not performed. The effect of these differences on anatomic and functional outcomes is unknown. Patients who underwent LHM ...
de Barros Luiz Antonio Borelli - - 2013
Orthodontic extrusion with multidisciplinary treatment can provide predictable outcomes in selected situations, reducing the costs and the adaptation times of gingival tissues after implant integration. Forced orthodontic extrusion is strongly related to interactions of teeth with their supportive periodontal tissues. This article reports a case of orthodontic extrusion of the ...
Ohlow M-A - - 2013
Internet has become a significant resource for dissemination of medical information. We sought to investigate prevalence and usage patterns of Internet access among consecutive patients with cardiovascular diseases. A cross-sectional study was performed using a questionnaire as study tool. Among patients with Internet access, the type of health information sought ...
Fitch Kathryn K Milliman, One Pennsylvania Plaza, 38th Fl., New York, NY 10119, USA. - - 2013
Diabetes prevalence is increasing in the United States, yet the control of critical clinical metrics (e.g., hemoglobin A1c [A1c], blood pressure, and lipids) remains suboptimal. Lower A1c levels have been shown to be associated with lower diabetes complication rates, and reduced medical costs have been reported in individuals with diabetes ...
Cull David L - - 2013
A number of surgery practice models have been developed to address general and trauma surgeon workforce shortages and on-call issues and to improve surgeon satisfaction. These include the creation of acute or urgent care surgery services and "surgical hospitalist" programs. To date, no practice models corresponding to those developed for ...
McKelvey Karma L - - 2013
Background: Coordinated high-impact interventions and community-level changes in smoking behaviour norms effectively reduced prevalence of smoking among youth in many developed countries. Smoking trends among Jordanian adolescents are likely different than their Western counterparts and must be understood in the context of their daily lives to tailor interventions specifically for ...
Ostovic Marko - - 2013
To study the microanatomic edge structures of anterior lens capsule specimens derived from manual and femtosecond laser-assisted capsulotomies. Department of Ophthalmology, Goethe-University, Frankfurt, Germany. Experimental study. Of 60 eyes with lens removal and intraocular lens implantation, 30 received a manual capsulotomy and 30 received a femtosecond laser-assisted capsulotomy (Lensx, rigid ...
Valenzuela G A GA Wayne State University, 10000 Telegraph Road, Taylor, Michigan 48124, - - 2013
The outcome of high tibial osteotomy (HTO) deteriorates with time, and additional procedures may be required. The aim of this study was to compare the clinical and radiological outcomes between unicompartmental knee replacement (UKR) and total knee replacement (TKR) after HTO as well as after primary UKR. A total of ...
Nemlekar Poorva P 10222 Wateridge Circle, #176, San Diego, CA, 92121, USA. - - 2013
Promotion of prescription drug coupons and vouchers by pharmaceutical manufacturers has increased in recent years. These coupons and vouchers usually subsidize patients' cost-sharing obligations. In other words, drug companies pay for a patient's portion of the drug cost, and the remaining cost is paid by the patient and the patient's ...
Torres-Lugo Madeline M Department of Chemical Engineering, University of Puerto Rico, Mayaguez Campus, PO BOX 9000, Mayaguez, PR 00681, Puerto Rico. - - 2013
Clinical studies have demonstrated the effectiveness of hyperthermia as an adjuvant for chemotherapy and radiotherapy. However, significant clinical challenges have been encountered, such as a broader spectrum of toxicity, lack of patient tolerance, temperature control and significant invasiveness. Hyperthermia induced by magnetic nanoparticles in high-frequency oscillating magnetic fields, commonly termed ...
Batchu Ramesh B - - 2013
Enhancer of zeste homologue 2 (EZH2), a component of the chromatin modification protein complex, is upregulated in pancreatic ductal adenocarcinoma (PDAC), whereas loss of p53 and its downstream target, p21(waf1/cip1), is also observed frequently. We sought to investigate the role of the p53-p21(waf1/cip1) pathway in relation to EZH2-mediated inhibition of ...
Dai Chunyan - - 2013
Bone is one of the main target organs for the lanthanides (Ln). Biodistribution studies of Tm-based compounds in vivo showed that bone had significant uptake. But the effect of Tm(3+) on primary mouse bone marrow stromal cells (BMSCs) has not been reported. So we investigated the effect and underlying mechanisms ...
Han Frederick T - - 2013
Atrial fibrillation (AF) is the most common arrhythmia encountered in clinical practice today. Until recently, the therapeutic approaches for AF have been limited by imperfect risk prediction models and suboptimal approaches for AF ablation. Magnetic resonance imaging (MRI) for the detection of left atrial (LA) fibrosis and correlation of these ...
Chatu S - - 2013
Increasing use of diagnostic imaging in inflammatory bowel disease (IBD) has led to concerns about the malignant potential of ionising radiation in a cohort that have an increased lifetime risk of gastrointestinal malignancy. The aim was to quantify radiation exposure in IBD patients referred from primary care, determine predictors of ...
Wang Chen - - 2013
Corynebacterium glutamicum wild type lacks the ability to utilize the xylose fractions of lignocellulosic hydrolysates. In the present work, we constructed a xylose metabolic pathway in C. glutamicum by heterologous expression of the xylA and xylB genes coming from Escherichia coli. Dilute-acid hydrolysates of corn cobs containing xylose and glucose ...
Han Guanghong - - 2013
Orthodontic forces produce a series of changes in dental pulp. However, no one has attempted to investigate the incidence of pulp necrosis after orthodontic therapy in the clinic. In this study, we aimed to investigate pulp vitality and histologic changes after the application of moderate and severe intrusive forces. Twenty-seven ...
Wisniewski J A JA Asthma and Allergic Diseases Center, University of Virginia Health System, Charlottesville, VA, - - 2013
Atopic dermatitis (AD) is common in children; however, persistence of AD with or without asthma is less common. Longitudinal studies remain limited in their ability to characterize how IgE antibody responses evolve in AD, and their relationship with asthma. To use a cross-sectional study design of children with active AD ...
Seims Aaron D - - 2013
Partial splenectomy is utilized selectively in children with hereditary spherocytosis (HS) to decrease hemolysis while maintaining immunity. Our aim was to compare outcomes between laparoscopic total splenectomy (LTS) and laparoscopic partial splenectomy (LPS). After obtaining institutional review board approval, we reviewed the records for all children ≤18 years with HS ...
Sabino Jennifer J Bethesda and Baltimore, Md.; Washington, D.C.; and Pittsburgh, Pa. From the Division of Plastic and Reconstructive Surgery, Walter Reed National Military Medical Center; the Department of Plastic and Reconstructive Surgery, Georgetown University; Johns Hopkins University School of Medicine; Uniformed Services University of Health Sciences; and the Department of Plastic and Reconstructive Surgery, University of Pittsburgh Medical - - 2013
Combat injuries commonly result in massive bony and soft-tissue destruction within the extremities. These extremity wounds often require large free tissue transfers and/or composite flaps for definitive reconstruction. In U.S. military war trauma experience, the authors' practice has found the scapular flap increasingly useful for reconstruction of complex extremity injuries. ...
Fahim Ramy - - 2013
Surgical management of the pediatric forefoot often brings challenges to the foot and ankle surgeon. It requires a thorough understanding of the pathologic abnormality and underlying causes involved, which include the contributing genetic conditions. Albeit most of the deformities carry a rare level of incidence, they do however have a ...
Kirby M M The Centre for Research in Primary and Community Care (CRIPACC), University of Hertfordshire, Hatfield, Herts, - - 2013
To compare efficacy and tolerability between 100-mg and 50-mg sildenafil doses in five double-blind, placebo-controlled (DBPC) fixed-dose studies. Doses were compared for the change (baseline to end of 8-12 weeks of DBPC treatment) in score on the Erectile Function (EF) domain of the International Index of Erectile Function (IIEF; from ...
Danno Karine K Laboratoires Boiron, 20, rue de la Liberation, F-69110 Sainte-Foy-les-Lyon, France. - - 2013
Pharmacists play an increasing role in advising on treatment for minor illnesses such as influenza-like illness (ILI) or ear, nose, and throat (ENT) disorders. However, the profile of patients consulting pharmacists with these illnesses, the types of over-the-counter (OTC) medicines recommended by pharmacists, and the effectiveness of these treatments have ...
Wybourn Christopher A - - 2013
Biliary dyskinesia (BD) is described as biliary colic in the absence of gallstones. The diagnosis relies on imaging studies and decreased excretion of bile in response to cholecystokinin during quantitative cholescintigraphy. The purpose of this study was to evaluate the success of laparoscopic cholecystectomy (LC) for relieving symptoms in patients ...
Zhang Miao - - 2013
To follow-up the outcomes with patients who have had 2 consecutive "atypical foci suspicious for carcinoma (ATYP)" diagnoses from prostate biopsies. A total of 516 men who had prostate core biopsy specimens with 2 sequential diagnoses of ATYP from 2003 to 2012 from 1 institution were studied. Of the 516 ...
Isomura Emiko T ET Suita and Yao, Osaka, Japan From the First Department of Oral and Maxillofacial Surgery, Osaka University, Graduate School of Dentistry; and the Department of Oral and Maxillofacial Surgery, Yao Municipal - - 2013
Bifocal distraction osteogenesis has been shown to be a reliable method for reconstructing missing bone segments. However, there are no reports regarding inferior alveolar nerve regeneration during bifocal distraction. In the present study, the authors evaluated the function of inferior alveolar nerve regenerated by bifocal distraction after segmental resection in ...
Scott C E H - - 2013
As many as 25% to 40% of unicompartmental knee replacement (UKR) revisions are performed for pain, a possible cause of which is proximal tibial strain. The aim of this study was to examine the effect of UKR implant design and material on cortical and cancellous proximal tibial strain in a ...
Salehi Sonja - - 2013
The aim of this study was to investigate oral rehydration therapy (ORT) products and their effect on plaque pH under normal and dry mouth conditions. Three commercial oral rehydration therapy products, prepared according to the manufacturers' instruction, plus a 10% glucose solution, which served as control, were tested in 10 ...
Kellam Melissa D - - 2013
The potential that forced-air warming systems may increase the risk of surgical site infections (SSIs) by acting as a vector or causing unwanted airflow disturbances is a concern to health care providers. To investigate this potential, we examined the literature to determine whether forced-air warming devices increase the risk of ...
Li J - - 2013
Little is known about time trend of prevalence of asthma and the association between the changing prevalence and allergen sensitization in Chinese children. To determine the changes in prevalence of asthma and allergen sensitization in schoolchildren over a period of 15 years. A total of 6928 schoolchildren aged 13-14 years in 2009 ...
Tulloch Ayesha I T - - 2013
To choose among conservation actions that may benefit many species, managers need to monitor the consequences of those actions. Decisions about which species to monitor from a suite of different species being managed are hindered by natural variability in populations and uncertainty in several factors: the ability of the monitoring ...
Lada Michal J - - 2013
Screening for esophageal adenocarcinoma (EAC) has not become policy in part over concerns in identifying the high-risk group. It is often claimed that a significant proportion of patients developing EAC do not report preexisting reflux symptoms or prior treatment for gastroesophageal reflux disease (GERD). As such, our aim was to ...
Amsdell Simon L SL Rochester, N.Y. From the Department of Orthopedics and Division of Plastic Surgery, University of Rochester Medical - - 2013
High-pressure injection injury to the hand and upper extremity is a rare but very serious clinical entity. The objective of this article was to review the current available literature and highlight important topics. A PubMed literature search was undertaken with the terms "high pressure injection injuries," "injection injuries," "finger injection ...
Morris Sheldon R - - 2013
HIV coreceptor usage of CXCR4 (X4) is associated with decreased CD4+ T-cell counts and accelerated disease progression, but the role of X4 tropism in HIV-associated neurocognitive disorders (HAND) has not previously been described. This longitudinal study evaluated data on 197 visits from 72 recently HIV-infected persons who had undergone up ...
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