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Results 201 - 250 of 4329
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Mirastschijski Ursula U Bremen, Hannover, and Essen, Germany From the Department of Plastic, Reconstructive, and Aesthetic Surgery, Klinikum Bremen-Mitte, Center for Biomolecular Interactions Bremen and Collaboration Center Medicine, University of Bremen; the Department of Plastic, Hand, and Reconstructive Surgery, Hannover Medical School; and the Division of Plastic and Reconstructive Surgery, Clinic for Senologie/Breast Center, Kliniken Essen-Mitte Evang. Huyssens Stiftung/Knappschaft - - 2013
Xenogenous dermal matrices are used for hernia repair and breast reconstruction. Full-thickness skin replacement is needed after burn or degloving injuries with exposure of tendons or bones. The authors used a human skin organ culture model to study whether porcine reconstructive tissue matrix (Strattice) is effective as a dermal tissue ...
Andreasen Laura - - 2013
Both shortening and prolongation of the QTc interval have been associated with atrial fibrillation (AF). We investigated whether 8 single nucleotide polymorphisms (SNPs) at loci previously shown to affect QTc interval duration were associated with lone AF. We included 358 patients diagnosed with lone AF (defined as onset of AF ...
Etzkorn Jeremy R - - 2013
The incidence of melanoma and nonmelanoma skin cancer continues to increase. To detect lesions at an earlier phase in their progression, skin cancer screening programs have been advocated by some. However, the effectiveness of skin cancer screening and the ideal population that these screenings should target have yet to be ...
Hales J - - 2013
The aim of this study was to investigate the effects of individual physical characteristics on preweaning survival and growth of piglets born in a noncrate system. Data were collected from 3,402 neonatal piglets from 203 Landrace × Yorkshire sows housed in noncrate pens in a commercial Danish sow herd. Piglets ...
Krishnan Vinod V Professor, Department of Orthodontics, Sri Sankara Dental College, Trivandrum, Kerala, India. Electronic address: - - 2013
Publishing a scientific article in a journal with a high impact factor and a good reputation is considered prestigious among one's peer group and an essential achievement for career progression. In the drive to get their work published, researchers can forget, either intentionally or unintentionally, the ethics that should be ...
Monteiro Rosebel - - 2013
To determine practice patterns/outcomes and educational opportunities in endocrine surgery by resident involvement in general surgery (GS) and otolaryngology (ENT). We queried the American College of Surgeon National Surgical Quality Improvement Program for thyroid/parathyroid operations. Resident involvement was categorized by postgraduate year (PGY) and specialty. Of 38,257 thyroid patients, attendings ...
Walker Sarah K - - 2013
The spectrum of pediatric biliary tract disease is changing. The goal of this study was to examine the causes and comorbidities of pediatric gallbladder disease at our institution. We performed a retrospective chart review on consecutive patient at Kosair Children's Hospital who underwent cholecystectomy over a 9-year time period ending ...
Sunil Vidya - - 2013
In March 2008, an enteric outbreak was reported from a correctional facility in Central East Ontario to the Haliburton, Kawartha, Pine Ridge District Health Unit. The clinical and epidemiological data were compatible with the presence of norovirus in this enteric outbreak. This report summarizes the outbreak investigation conducted and the ...
Yecies Todd - - 2013
Fournier's gangrene is a fulminant, necrotizing soft-tissue infection of the genital, perineal, and perianal regions. Fournier's isolated to the penis is a rare occurrence due the highly vascular nature of the penis. Reported occurrences of penile Fournier's gangrene have occurred in the setting of a clear vascular or traumatic insult. ...
Patel Kamlesh B KB St. Louis, Mo. From the Division of Plastic and Reconstructive Surgery, Washington University in St. - - 2013
Common variations in morphology of the medial crura have been described. The authors' observation is that changes in nasal tip projection depend on the shape and strength of the medial crura. The authors investigated how differences in medial crura shape affect tip projection after surgical intervention. Seventeen cadaver heads were ...
Nayeemuddin Mohammed - - 2013
In 2000, the US Food and Drug Administration approved the da Vinci Surgical System® for use in the United States. Since that time, the number of surgical robotic systems throughout the United States has continued to grow. The costs for using the system include the initial purchase ($1 million to ...
Pinto L A - - 2013
Interferon-regulatory factors (IRFs) play a crucial role in immunity, not only influencing interferon expression but also T cell differentiation. IRF-4 was only recently recognized as a further major player in T cell differentiation. As IRF-1 polymorphisms were shown to be associated with atopy and allergy, we comprehensively investigated effects of ...
Tarras Samantha L - - 2013
Pre-injury vagal nerve stimulation protects against gut and lung injury after experimental hemorrhagic shock (HS). This likely occurs via the cholinergic anti-inflammatory pathway and the α7 nicotinic acetylcholine receptor (α7nAChR). We hypothesized that, in an in vitro model, either nicotine or a selective α7nAChR agonist (AR-R17779) would modulate intestinal and pulmonary effects ...
Jayanti Anuradha - - 2013
Resurgence of interest in home haemodialysis (HHD) is, in part, due to emerging evidence of the benefits of extended HD regimens, which are most feasibly provided in the home setting. Although specific HHD therapy established at home such as nocturnal HD (NHD) has been reported from individual programmes, little is ...
Bloom Jacob M P JM Rochester, N.Y. From the Division of Plastic Surgery and the Department of Orthopedics, University of Rochester Medical - - 2013
The mallet finger is a frequently encountered fingertip injury that leads to extensor lag of the distal phalanx. Classification systems stratify these injuries as ranging from soft-tissue disruption of the extensor mechanism alone to those that have articular involvement and volar subluxation. The management of mallet finger injuries varies based ...
Ahdesmäki Miika - - 2013
Abstract Model selection between competing models is a key consideration in the discovery of prognostic multigene signatures. The use of appropriate statistical performance measures as well as verification of biological significance of the signatures is imperative to maximise the chance of external validation of the generated signatures. Current approaches in ...
Chia Gloryn - - 2013
Abstract The remarkable ability of oocytes to reinstate the totipotent state from a unipotent somatic cell, allowing the cloning of animals and the generation of human stem cells, has fascinated scientists for decades. Due to the complexity of oocytes, it has remained challenging to understand the rapid reprogramming following nuclear ...
Vaquerizo Víctor - - 2013
The purpose of this study was to compare the efficacy and safety in a randomized, clinical trial of 3 injections of PRGF-Endoret (BTI Biotechnology Institute, Vitoria, Spain) versus one single intra-articular injection of Durolane hyaluronic acid (HA) (Q-MED AB, Uppsala, Sweden) as a treatment for reducing symptoms in patients with ...
Lernia Vito Di - - 2013
Epstein-Barr virus (EBV) is a human B-lymphotropic herpes virus and one of the most common viruses in humans. Specific skin signs related to EBV infection are the exanthem of mononucleosis, which is observed more frequently after ingestion of amoxicillin, and oral hairy leukoplakia, a disease occurring mostly in immunocompromised subjects ...
Bello Danielle M - - 2013
Malignant melanoma is the most fatal type of skin cancer. Traditional melanoma classification has been based on histological subtype or anatomical location. However, recent evidence suggests that melanoma comprises a group of diseases characterized by distinct molecular mutations. These mutations affect disease behavior but provide unique opportunities for targeted therapy. ...
Kruithof-de Julio Marianna - - 2013
Inhibition of canonical Wnt signaling affects prostate bud outgrowth and luminal epithelial differentiation in explant culture. Immunostaining for FoxA1 (red) and cytokeratin 5 (green) in a section from a 15.5 dpc urogenital sinus explant cultured for 7 days in Dkk1-containing media. From Canonical Wnt Signaling Regulates Nkx3.1 Expression and Luminal ...
Mali Prashant P Department of Genetics, Harvard Medical School, Boston, Massachusetts, - - 2013
RNA-guided Cas9 nucleases derived from clustered regularly interspaced short palindromic repeats (CRISPR)-Cas systems have dramatically transformed our ability to edit the genomes of diverse organisms. We believe tools and techniques based on Cas9, a single unifying factor capable of colocalizing RNA, DNA and protein, will grant unprecedented control over cellular ...
Levine Steven M SM New York, N.Y; Charleston, S.C.; and New Orleans, La. From the Institute of Reconstructive Plastic Surgery, New York University Langone Medical Center; Medical University of South Carolina; Tulane University Health Science Center; and Louisiana State University School of - - 2013
Recent evolutions of oncologic breast surgery and reconstruction now allow surgeons to offer the appropriate patients a single-stage, autologous tissue reconstruction with the least donor-site morbidity. The authors present their series of buried free flaps in nipple-sparing mastectomies as proof of concept, and to explore indications, techniques, and early outcomes ...
Jacobs Michelle M - - 2013
It has been postulated that drugs of abuse act synergistically with HIV, leading to increased neurotoxicity and neurocognitive impairment. The CNS impacts of HIV and drug use converge on the mesocorticolimbic dopamine (DA) system, which contains two main receptor subtypes: dopamine receptors 1 (DRD1) and 2 (DRD2). DRD1 and DRD2 ...
Gao H - - 2013
Breeding animals can be accurately evaluated using appropriate genomic prediction models, based on marker data and phenotype information. In this study, direct genomic values (DGV) were estimated for 16 traits of Nordic Total Merit (NTM) Index in Nordic Red cattle population using three models and two different response variables. The ...
Radwan M M - - 2013
The objective of the study was to evaluate anti-apolipoprotein A-I (Apo A-I) and carotid intima-media thickness (cIMT) as cardiovascular risk factors in Egyptian women with systemic lupus erythematosus (SLE). The study included 160 subjects, 80 women with SLE and 80 healthy women as a control group. Disease activity score (SLEDAI), ...
Wills A K - - 2013
It has been suggested that maternal vitamin D status in pregnancy influences the risk of asthma and atopy in the offspring. The epidemiological evidence to support these claims is conflicting and may reflect chance findings and differences in how vitamin D was assessed. To examine the association between blood total ...
Alexander Matthew S - - 2013
Acute care surgery (ACS) remains in its infancy as a defined surgical specialty within hospital systems. Little has been published regarding the financial impact of this method of care delivery to hospital systems and departments when combining trauma, surgical critical care, emergent, and elective general surgery into a single practice ...
Seruya Mitchel M Melbourne, Victoria, Australia From the Department of Plastic and Maxillofacial Surgery and the Department of Neurosurgery, Royal Children's Hospital Melbourne; and the Department of Paediatrics, University of - - 2013
Total vault reconstruction addresses all phenotypic aspects of scaphocephaly. The clinical implications of remodeling across open cranial sutures, however, remain unclear. The purpose of this study was to assess patency of unaffected sutures following total vault remodeling for isolated sagittal synostosis. The authors reviewed routine postoperative computed tomographic scans of ...
Matic Marija - - 2013
Glutathione S-transferases (GSTs) are a family of enzymes involved in detoxification. Genes encoding for GSTA1, GSTM1, GSTP1, and GSTT1 proteins are polymorphic, which can result in complete or partial loss of enzyme activity. Previous studies have associated polymorphisms of GSTA1, GSTM1, and GSTP1 genes with a higher risk of bladder ...
Matsumoto T - - 2013
The main form of treatment of a chordoma of the mobile spine is total en bloc spondylectomy (TES), but the clinical results are not satisfactory. Stand-alone carbon ion radiotherapy (CIRT) for bone and soft-tissue sarcomas has recently been reported to have a high rate of local control with a low ...
Verbalis Joseph G JG Georgetown University Medical Center, Washington, DC. Electronic address: - - 2013
Hyponatremia is a serious, but often overlooked, electrolyte imbalance that has been independently associated with a wide range of deleterious changes involving many different body systems. Untreated acute hyponatremia can cause substantial morbidity and mortality as a result of osmotically induced cerebral edema, and excessively rapid correction of chronic hyponatremia ...
Nagura Saori - - 2013
Abstract Regenerative therapy is a new strategy for the end-stage heart failure; however, the ideal cell source has not yet been established for this therapy. We expected that the amnion might be an ideal cell source for cardiac regenerative therapy and that the differentiation potency of the human amnion mesenchymal ...
Caucanas Marie - - 2013
Background  The association of three neutrophilic dermatoses supports the concept of "neutrophilic disease" as a syndrome representing a continuous spectrum of clinical entities. Results  This report describes three neutrophilic pathologies arising in the same patient, in association with seronegative rheumatoid arthritis. The successive occurrence of erythema elevatum diutinum, pyoderma gangrenosum, ...
Kudchadkar Ragini R - - 2013
The previous 2 years have been an exciting time in melanoma research, due in part to the approval of vemurafenib and ipilimumab for advanced melanoma. Increased knowledge of the molecular biology leading to melanoma has led to the development of several new agents that target specific oncogenes. The authors review ...
Park Dae Hwan DH Daegu and Ulsan, Republic of Korea From the Department of Plastic and Reconstructive Surgery, College of Medicine, Catholic University of Daegu; and the Department of Plastic and Reconstructive Surgery, Dong Kang General - - 2013
In ptosis surgery, not addressing the epicanthal fold leaves a persistent rounded nasal scleral triangle, which blunts the effect of ptosis repair and leads to patient dissatisfaction. To achieve satisfactory results, epicanthoplasty is usually performed with ptosis correction. Furthermore, surgeons usually choose epicanthoplasty methods based on personal preference, and no ...
Li Chaoyun - - 2013
Abstract Minocycline is a semisynthetic second-generation tetracycline derivative, and many publications provide evidence of its successful neuroprotection in a variety of animal models. We searched PubMed and Chinese CNKI databases from January 1992 to May 2012 for studies on minocycline in neurodegenerative diseases in rodents. A meta-analysis that adopted weighted ...
Ishida Takayoshi - - 2013
In nongrowing patients with skeletal Class II malocclusion, premolar extraction or maxillary distalization can be used as camouflage treatment. Zygomatic anchorage enables distalization in uncooperative or noncompliant patients. We describe 1 such procedure in a 24-year-old woman. We used novel improved superelastic nickel-titanium archwires combined with nickel-titanium open-coil springs to ...
Krishna K Vijaya - - 2013
Graphene family nanomaterials are currently being extensively explored for applications in the field of nanotechnology. The unique intrinsic properties treasured in their simple molecular design and their ability to work in coherence with other existing nanomaterials make graphene family nanomaterials the most promising candidates for different types of applications. This ...
Mehta Rohtesh S - - 2013
In thyroid nodule fine-needle aspiration (FNA) cytology, the atypia of undetermined significance or follicular lesion of undetermined significance (AUS/FLUS) category has a 5-15% malignancy risk that increases to 85-99% when mutation testing for BRAF, RAS, RET/PTC, or PAX8/PPARγ is positive. However, negative testing does not exclude malignancy. The study objective ...
Feaster Daniel J DJ 1Department of Public Health Sciences, University of Miami, Miami, FL, - - 2013
The prevalence of HIV infection among male prison inmates is significantly higher than in the U.S. population. Adequate planning to ensure continued medication adherence and continuity of care after release is important for this population. This study describes the prerelease characteristics of 162 incarcerated HIV-positive men (40 from jails and ...
Yang Chao C Shanghai, People's Republic of China From the Department of Plastic Surgery, Changhai Hospital, Second Military Medical - - 2013
The tear trough and palpebromalar groove are of increasing interest to plastic surgeons, but their mechanisms of formation remain unclear. This study evaluated the anatomical foundation for tear trough and palpebromalar groove. Sagittal dissection and layered dissection were performed on 20 elderly cadaveric hemifaces with obvious tear troughs and palpebromalar ...
Flynn Timothy Corcoran TC Cary and Chapel Hill, N.C.; and West Lafayette, Ind. From the Cary Skin Center; the Department of Dermatology, University of North Carolina at Chapel Hill; the Department of Chemistry, Purdue University; and Pandion Laboratories, - - 2013
In this study, the authors sought to determine the molecular weight distribution of three hyaluronic acids-Belotero Balance, Restylane, and Juvéderm Ultra-and their rates of degradation following exposure to hyaluronidase. Lot consistency of Belotero Balance also was analyzed. Three lots of Belotero Balance were analyzed using liquid chromatography techniques. The product ...
Jones James W - - 2013
During your preoperative visit, a very wealthy patient, Gill Bates, who donated a wing to the large teaching hospital in which you practice, has an unusual request: He does not want any residents involved with his care. He is scheduled for an open infrarenal aneurysmectomy. He explains that his decision ...
Siracusa Mark C MC Department of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pa; Institute for Immunology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, - - 2013
Basophils were discovered by Paul Ehrlich in 1879 and represent the least abundant granulocyte population in mammals. The relative rarity of basophils and their phenotypic similarities with mast cells resulted in this cell lineage being historically overlooked, both clinically and experimentally. However, recent studies in human subjects and murine systems ...
Aksoy Erol - - 2013
Over the last decade, radiofrequency thermal ablation (RFA) has been incorporated into the treatment algorithm of patients with unresectable colorectal liver metastases (CLM). For this population, the local recurrence (LR) rate is a key parameter used to assess the success of RFA. LR is defined as development of new tumor ...
Core Grady B GB Birmingham, Ala. From the University of - - 2013
Effective lower eyelid blepharoplasty is possible in a virtually closed fashion without either an anterior subciliary skin incision or a transconjunctival incision, both of which put the patient at risk for lower lid retraction. Over a 6-year period, the author performed lower lid rejuvenation with only a lateral incision in ...
Hardes J - - 2013
We evaluated the clinical results and complications after extra-articular resection of the distal femur and/or proximal tibia and reconstruction with a tumour endoprosthesis (MUTARS) in 59 patients (mean age 33 years (11 to 74)) with malignant bone or soft-tissue tumours. According to a Kaplan-Meier analysis, limb survival was 76% (95% confidence ...
Armitage James O JO Department of Medicine, University of Nebraska Medical Center, Omaha, - - 2013
T-cell lymphomas make up approximately 10-15% of lymphoid malignancies. The frequency of these lymphomas varies geographically, with the highest incidence in parts of Asia. The diagnosis of aggressive peripheral T-cell lymphoma (PTCL) is usually made using the WHO classification. The ability of hematopathologists to reproducibly diagnosis aggressive PTCL is lower ...
Hayashi Kazuo - - 2013
The primary objective of this study was to assess the accuracy and the reliability of the SureSmile OraScanner (Orametrix, Richardson, Tex) by comparing it with other desktop 3-dimensional scanners: VIVID910 (Konica Minolta, Tokyo, Japan) and R700 (3Shape, Copenhagen, Denmark). A laser-based scanner, the SLP250 Laser Probe (Laser Design, Detroit, Mich), ...
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