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Results 451 - 500 of 4329
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Pirogovsky Eva - - 2013
Few studies have examined instrumental activities of daily living (iADLs) in nondemented Parkinson's disease (PD), and the majority of these studies have used report-based measures, which can have limited validity. The present study had two main goals: (a) to examine the performance of nondemented PD patients on two performance-based measures ...
Liu Dazhi - - 2013
Small-angle neutron scattering (SANS) is the most significant neutron technique in terms of impact on science and engineering. However, the basic design of SANS facilities has not changed since the technique's inception about 40 years ago, as all SANS instruments, save a few, are still designed as pinhole cameras. Here ...
Vandenbergh Joke - - 2013
An effective procedure to synthesize sequence controlled oligoacrylates with up to four monomer insertions via the RAFT technique is presented. Two different sets of oligomers with a preferred monomer order were synthesized. Recycling SEC allowed for facile and automated purification of the monodisperse sequence-controlled materials.
Kubota Takayuki - - 2013
The consumption of probiotics by pregnant and lactating women may prevent the onset of allergic disorders in their children by increasing the concentrations of immunoactive agents such as cytokines in breast milk. Prebiotics such as fructo-oligosaccharides (FOS) increase the number of beneficial organisms such as bifidobacteria. Thus, prebiotics may have ...
Dai Da-peng DP The Key Laboratory of Geriatrics, Beijing Hospital & Beijing Institute of Geriatrics, Ministry of Health, Beijing 100730, - - 2013
Cytochrome P450 2C9 (CYP2C9) is a polymorphic enzyme that is responsible for the metabolism of approximately 15% of clinically important drugs. The aim of this study was to assess the catalytic characteristics of 37 CYP2C9 allelic isoforms found in Chinese Han population on the metabolism of tolbutamide in vitro. The ...
Aharonovich Sinai - - 2013
New bis(N,N-trimethylsilylarylamidinate) zirconium dichloride complexes with various carbon substituents were prepared, and their solid as well as solution state structures were studied. In the polymerization of propylene, after activation by MAO, these catalysts provided two fractions. Ether soluble polymers were obtained at a low activity as sticky polymers with lower ...
Bray Kristi - - 2013
The Rho GTPase Cdc42 is overexpressed and hyperactivated in breast tumors compared to normal breast tissue. Cdc42 regulates key processes that are critical for mammary gland morphogenesis and become disrupted during the development, progression, and metastasis of breast cancer. However, the contribution of Cdc42 to normal and neoplastic mammary gland ...
Smith S M - - 2013
This review seeks to provide a current overview of musculo-skeletal pain in overweight and obese children. Databases searched were Academic Search Complete, CINAHL, Medline, Proquest Health and Medical Complete, Scopus, Google Scholar, SPORTDiscuss, and Trove for studies published between January 1, 2000 and December 30, 2012. We used a broad ...
Song Yuze - - 2013
The emergence, resurgence and spread of human food-borne pathogenic Vibrios are one of the major contributors to disease burden and mortality particularly in developing countries with disputable sanitary conditions. Previous research on pathogenic Vibrio cholerae and Vibrio parahaemolitycus derived from clinical samples has proposed links between acquisition of virulence and ...
Xie Xiaochen - - 2013
The radical cation [1,2-B2{1,2-(MeN)2C6H4}2]˙(+) has been synthesised and its structure and bonding have been probed using a combination of X-ray crystallography, EPR spectroscopy and DFT calculations which show that it represents a new type of radical centred primarily on two N-heterocyclic units joined by a B2 linker but with only ...
Knoll Thomas - - 2013
In the current work, Zeng et al. report one of the largest series on miniaturized PNL until now. They demonstrate that this approach is reasonable and effective - although there are some limitations of the study. Mini PNL seems to become more and more a standard procedure.
Garfield Lauren D - - 2013
Objectives. Studies have reported an association between serotonin reuptake inhibitors (SRIs) and accelerated bone loss. Genetic variation in the serotonin system might modulate bone metabolism changes during SRI treatment. In a clinical trial we examined functional genetic polymorphisms of serotonin transporter and receptors involved in bone metabolism to determine whether ...
Ortiz Johana - - 2013
To identify and compare the sociodemographic determinants of stunting, wasting and overweight among infants of urban and rural areas in the Ecuadorian highlands. Cross-sectional study. Nabon (rural) and Cuenca (urban) cantons, Azuay Province, Ecuador. A total of 703 children aged 0-24 months and their caregivers (227 rural and 476 urban) ...
Fernández de Larrea C - - 2013
The achievement of CR is the crucial step for a prolonged PFS and OS after an autologous SCT in multiple myeloma (MM). Unfortunately, even with the use of new regimens and the current high CR rates, most, if not all, patients will ultimately relapse or progress. We analyzed the type ...
Knoepfli-Lenzin Claudia - - 2013
Abstract The aim of this study was to assess the validity of the heart rate formula 170 - 0.5 age ± 10 used to prescribe endurance training for healthy sedentary or moderately trained individuals. A total of 795 incremental tests of women and men during running and cycling were analysed. The maximum heart ...
Tong Shuang - - 2013
The pathological damage inflicted by virulent AIV strains is often caused by inducing a positive feedback loop of cytokines in immune cells that cause excessive inflammation. Previous research has shown that a G protein-coupled receptor, sphingosine-1-phosphate receptor 1 (S1PR1), plays a crucial role in the development of excessive inflammation in ...
Saxena Sudhanshu - - 2013
Commonly consumed fruits showed remarkable variation in antimutagenicity when assayed by E. coli rifampicin resistance assay, and Java Plum (Syzygium cumini) was found to be one of the most potent fruits. Its anthocyanins contributed maximally to the observed antimutagenicity and resolved into three distinct bands in HPTLC. Although these bands ...
Aynali G - - 2013
Objective: To investigate the relationship between development of laryngeal cancer and the presence of polymorphisms of the MnSOD Val16Ala, CAT-262 C < T and GPx1 Pro198Leu genes in a smoking population. Patients and methods: Single nucleotide polymorphisms were determined in DNA from the peripheral blood erythrocytes of 48 heavy smokers (25 patients ...
Senthil Kumar Karuppannan - - 2013
A new type of device is presented that allows direct measurement of spin selectivity in charge transfer processes occurring in adsorbed molecules. The new device provides direct information about the nature of the charge being transferred (electrons or holes) and on spin selectivity, if it exists. Here the device is ...
Haake Steve J - - 2013
Abstract Improvements in track and field sports have been attributed to factors such as population increase, drugs and new technologies, but previous research has found it difficult to distinguish the contributions from specific influences. Here it is shown how this is possible by means of a performance improvement index based ...
Koskimies Pasi - - 2013
Objective: To characterize the pharmacokinetics of the oral, non-estrogen agent ospemifene, an estrogen agonist/antagonist with tissue-selective effects (also called a selective estrogen receptor modulator) that was recently approved for the treatment of dyspareunia associated with vulvar and vaginal atrophy in postmenopausal women. Methods: Two open-label, Phase 1 studies were conducted ...
Song Jibin - - 2013
We have developed surface-initiated organocatalytic ring opening polymerization on functional nanocrystals and synthesized amphiphilic gold nanorods carrying well-defined mixed polymer brushes of poly(ethylene glycol) and polylactide. Self-assembly of the amphiphilic gold nanorods affords biodegradable plasmonic vesicles that can be destructed by both enzymatic degradation and near-infrared photothermal heating. When tagged ...
Gallegos Miguel - - 2013
This paper presents a historical overview of the Interamerican Society of Psychology, which was founded on December 17, 1951, in Mexico City. Firstly, the historical circumstances of the foundation period are presented, as well as the people who made this organization possible, and the state of psychology on the American ...
Haglund Lena - - 2013
Abstract Aim: This paper reports the measurement properties of the Occupational Circumstances Assessment Interview and Rating Scale - Sweden (OCAIRS-S V2). The OCAIRS is a semi-structured interview and rating scale designed to capture, in detail, a person's occupational participation. The English version 4.0 has been translated into Swedish. The psychometric ...
Pavoni Emiliano - - 2013
Consistent progress in the development of bacteriophage lambda display platform as an alternative to filamentous phage display system was achieved in the recent years. The lambda phage has been engineered to display efficiently multiple copies of peptides or even large protein domains providing a powerful tool for screening libraries of ...
Ji Guixiang - - 2013
DNA adducts are widely used marker of DNA damage induced by environmental pollutants. The present study was designed to explore whether sperm polycyclic aromatic hydrocarbon-DNA adducts were associated with sperm DNA integrity and semen quality. A total of 433 Han Chinese men were recruited from an infertility clinic. Immunofluorescence was ...
Kagawa Yuki - - 2013
Several possible scenarios of cellular dynamics in human colonic crypts have been inferred from transgenic animal experiments. However, because of the discrepancy in size and physiology between humans and animals, quantitative predictions of tissue renewal and cancer development are difficult to execute. A two-dimensional individual based model was developed for ...
Stenlöf Kaj - - 2013
Abstract Objective: Canagliflozin is a sodium glucose co-transporter 2 inhibitor developed for treatment of type 2 diabetes mellitus (T2DM). The long-term efficacy and safety of canagliflozin monotherapy were evaluated over 52 weeks in patients with T2DM inadequately controlled with diet and exercise. Research design and methods: This randomized, double-blind, Phase ...
Hur S J - - 2013
Abstract This study investigated the effects of onion (Allium cepa, L.) extract on the antioxidant activity of lipids in low and high fat-fed mouse brain lipids and its structural change during in vitro human digestion. The onion extracts were then passed through an in vitro human digestion model that simulated ...
Winkler Cornelia - - 2013
Abstract Objective. Bacterial adhesion on and cytotoxicity of eight luting agents used for implant-supported restorations were investigated. Materials and method. Surface roughness (Ra), surface free energy (SFE) values and three-dimensional images by atomic-force microscopy of circular specimens were determined. Bacterial suspensions of Streptococcus sanguinis and Streptococcus epidermidis were incubated at ...
Potkin Steven G SG University of California-Irvine, School of Medicine, Irvine, California, - - 2014
OBJECTIVE/INTRODUCTION: Lurasidone is an atypical antipsychotic medication approved for the treatment of schizophrenia over a dose range of 40-160 mg/day. This study examined D2 receptor occupancy and its association with clinical improvement and side effects in patients with schizophrenia or schizoaffective disorder following repeated doses of 80, 120, or 160 ...
Wang Panpan - - 2013
An ultrasensitive photoelectrochemical (PEC) immunoassay was introduced into microfluidic paper-based analytical devices (μ-PADs) based on a multiple electron transfer system for the first time, which was constructed using narrow-band-gap semiconductor nanoparticles (NPs), wide-band-gap semiconductor NPs, and an electron-accepting medium.
Reggiani-Bonetti Luca - - 2013
Abstract Objectives. The purposes of the study are to describe the incidence trend of malignant polyp of large bowel over a 25-year period in the District of Modena and to assess the effect of an organized colorectal cancer screening program. Material and methods. Through the data of a specialized colorectal ...
Cubillas Ciro - - 2013
The ubiquitous Cation Diffusion Facilitator proteins (CDF) play a key role in maintaining the cellular homeostasis of essential metal ions. Previous neighbor-joining phylogenetic analysis classified CDF proteins into three substrate-defined groups: Zn(2+), Fe(2+)/Zn(2+) and Mn(2+). These studies were unable to discern substrate-defined clades for Ni(2+), Co(2+), Cd(2+) and Cu(2+) transporters, ...
Liu Huagang - - 2013
Abstract Context: A classic traditional Chinese medicine, Zanthoxylum nitidum (Roxb.) DC. widely used in China, exhibits anticancer, anti-inflammatory and antianalgesic activities. Alkaloids are one of the main bioactive components. It is urgent to develop a simple and reliable method to determine the main alkaloids in Z. nitidum roots. Objective: To ...
Ueno Haruna - - 2013
Design and synthesis of a boronic acid based artificial receptor which selectively and effectively bound to a neurotransmitter, l-DOPA (), in aqueous media. In addition, the synthetic receptor was found to effectively inhibit the DDC (l-DOPA decarboxylase) enzymatic reaction under physiological conditions.
Takeda Mamoru - - 2013
The trigeminal subnuclei interpolaris/caudalis transition zones (Vi/Vc) play an important role in orofacial deep pain, however, the role of primary afferent projections to the Vi/Vc remains to be determined. This study investigated the functional significance of hyperalgesia to the brain-derived neurotrophic factor (BDNF)-tyrosine kinase B (trkB) signaling system in trigeminal ...
Chen Dapeng - - 2013
Abstract Context: Ginsenosides are primary active ingredients of ginseng, which are believed to have various health benefits. It is found that the biotransformation of ginsenosides mainly takes place in the gastrointestinal tract and the information about ginsenosides-exerted effects on intestinal contractility is not sufficient. Aims: The present study proposed that ...
Jurewicz Joanna - - 2013
Abstract The relationship between exposure to lifestyle factors and adverse effects on human reproductive health is debated in the scientific literature and these controversies have increased public and regulatory attention. The aim of the study was to examine the association between modifiable lifestyle factors and main semen parameters, sperm morphology, ...
Vargas Roger I - - 2013
We examined spatial patterns of both sexes of oriental fruit fly, Bactrocera dorsalis (Hendel), and its two most abundant parasitoids, Fopius arisanus (Sonan) and Diachasmimorpha longicaudata (Ashmead) in a commercial guava (Psidium guajava L.) orchard. Oriental fruit fly spatial patterns were initially random, but became highly aggregated with host fruit ...
Zhou Xuefeng - - 2013
Abstract Context: Epidioxy sterols and sterols with special side chains, such as hydroperoxyl sterols, usually obtained from marine natural products, are attractive for bioactivities. Objective: To isolate and screen bioactive and special sterols from China Sea invertebrates. Materials and methods: Two hydroperoxyl sterols (1 and 2) from the sponge Xestospongia ...
Chen Yan-Yan - - 2013
Methods From 2008 to 2010, 208 non-small cell lung cancer patients who underwent surgery or CT-guided biopsy were recruited from Huadong Hospital, Fudan University. Immunohistochemistry staining was performed to evaluate the PD-L1 expression in both primary lung cancer cells and CD68 positive TAM. The relationship between PD-L1 expression and the ...
Son Hyewon - - 2013
Ultrafast two-dimensional infrared (2DIR) spectroscopy was used to study H-bond exchange dynamics in aqueous NaPF6 solutions. Interestingly, there are two spectrally distinct hydrogen-bond (H-bond) configurations in aqueous NaPF6 solutions; water molecules that are H-bonded to PF6(-) ion (ODA) or other water molecules (ODW). These two spectrally distinct subsets of water ...
Yang Weiting - - 2013
MOF-76 exhibits not only high sensitivity for the detection of U(vi), but also high adsorption capacity of 298 mg g(-1) at a low pH value of ∼3.0. Furthermore, the high selectivity for uranium adsorption over a series of competing metal ions is also illustrated.
Torregrosa José-Vicente - - 2013
Background and objectives: Calcific uremic arteriolopathy (CUA) is a life-threatening condition almost exclusively affecting patients with end-stage renal failure. Several therapies have been employed to treat this disease with irregular results. Methods: Comparison of a prospective case series with a historical cohort. Group I: 12 patients with CUA diagnosed before ...
Pan Shu Sheng - - 2013
Direct bandgap semiconductors, such as In2O3, Cu2O, and SnO2, have enormous applications in photochemistry, photovoltaics, and optoelectronics. Due to the same parity of conduction and valence bands, the dipole transition is silent in these direct bandgap semiconductors. The low band-to-band transition efficiency prevents them from high intensity light emission or ...
Rose J D - - 2013
The advantages and disadvantages of different methods of carrying objects on spine loading are still not fully understood. Previous studies have either examined the effects of carrying using physiological measures or examined isolated spine segments using biomechanical models. Additionally, most studies have been restricted to only a small number of ...
Qin Songbing - - 2013
Purpose: In the presence of random uncertainties, delivered radiation treatment doses in patient likely exhibit a statistical distribution. The expected dose and variance of this distribution are unknown and are most likely not equal to the planned value since the current treatment planning systems cannot exactly model and simulate treatment ...
Wei Guang-Feng - - 2013
The electrocatalytic oxygen reduction reaction (ORR) on nanoparticles has attracted much attention in recent years for its significance in fuel cell applications. Here by combining density functional theory (DFT) calculations with the periodic continuum solvation model based on modified-Poisson-Boltzmann (CM-MPB) electrostatics, we analyzed the ORR activity on a set of ...
Liu Kang-Sheng - - 2013
Appropriate selection and measurement of lead biomarkers of exposure are critically important for health care management purposes, public health decision making, and primary prevention synthesis. Lead is one of the neurotoxicants that seems to be involved in the etiology of psychologies. Biomarkers are generally classified into three groups: biomarkers of ...
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