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Results 201 - 250 of 2728
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Li Ming - - 2013
Tumor necrosis factor alpha (TNFA) is an important molecule in inflammatory, infectious, and tumoral processes. Inflammation is one of the early phases in the development of gastric cancer (GC). Therefore, several studies have examined the association of polymorphism in TNFA with gastritis and GC risk. A functional polymorphism, -308G>A (rs1800629), ...
Dunkman Andrew A - - 2013
Defining the constituent regulatory molecules in tendon is critical to understanding the process of tendon repair and instructive to the development of novel treatment modalities. The purpose of this study is to define the structural, expressional, and mechanical changes in the tendon injury response, and elucidate the roles of two ...
Yuan Hushan - - 2013
Triphenylphosphonium-fluorochromes (TPP-fluorochromes) are a new class of spectrally variable, mitochondrially targeted probes, with an [(18)F] labeling option which, when enabled, allows imaging of a cardiac perfusion deficit using PET/CT.
Matsumoto C - - 2013
Objective: The purpose of this study was to improve accessibility to nursing care by clarifying the relationship between patient characteristics and the amount of nursing care for the Diagnosis Procedure Combination system (DPC). Method: The subjects included 528 lung cancer patients; 170 gastric cancer patients; and 91 colon cancer patients, ...
Matsui Tomohiro - - 2013
Therapeutic hypothermia protects neurons after severe brain damage. This effect has been mainly achieved at the core temperatures of 32-34 °C; however, the optimum temperature of therapeutic hypothermia is not fully defined. Here we studied whether hypothermic culture at 35 °C had the same effects on the decrease of time-dependent expression of ...
Choi Yong Sun - - 2013
To evaluate which factors affecting changes in postoperative renal function after conducting radical nephrectomy or partial nephrectomy. Data on patients who underwent operations for renal cell carcinoma between 2000 and 2010 at multiple institutions were collected. Patient characteristics including preoperative estimated glomerular filtration rate (EGFR) were investigated, and types of ...
Stachon Tanja - - 2013
With increasing resistance of microorganisms to antibiotics, photodynamic inactivation (PDI) may also be a potential therapeutic option in infectious keratitis. As part of the inflammatory response in infectious keratitis, keratocytes produce various interleukins. The purpose of this study was to evaluate the potential anti-inflammatory effect of PDI, analyzing interleukin-1 alpha ...
Qiu Huan - - 2013
Gene duplications restricted to single lineage combined with an asymmetric evolution of the resulting genes may play particularly important roles in this lineage's biology. We searched and identified asymmetrical evolution in nine gene families that duplicated exclusively in rodents and are present as single-copies in human, dog, cow, elephant, opossum, ...
Mahla E - - 2013
In patients pretreated with P2Y12 receptor inhibitors who need to undergo non-emergent cardiac or major non-cardiac surgery, current guidelines of the European Society of Cardiology recommend postponing surgery for at least five days after last intake of clopidogrel or ticagrelor, and for seven days after last intake of prasugrel, unless ...
Dent S F - - 2013
Purpose AT9283 is a potent inhibitor of the mitotic regulators, Aurora-kinases A and B, and has shown anti-tumor activity in patients with solid and haematological malignancies. This phase I study assessed safety, tolerability, pharmacokinetic and pharmacodynamic properties of AT9283. Patients and methods Patients with advanced, incurable solid tumors or non-Hodgkin's ...
Kaczmarek James C - - 2013
Purpose: To alter the composition and structure of silicone hydrogel contact lenses to achieve controlled release of dexamethasone and evaluate the lens optical and mechanical properties compared to commercial lenses. There is a tremendous need for controlled release of drugs from ocular biomaterials as the majority of ophthalmic drugs are ...
Lin Chun-Hsien - - 2013
Symptomatic thoracic compression fracture is one of the most common causes of back pain in elderly. Although vertebroplasty is widely utilized in patients when conservative treatment fails, we introduced an alternative percutaneous technique for the treatment of thoracic compression pain. This in a retrospective study. The analysis was performed on ...
Pastor Jesús - - 2013
Fluorescence-guided resection (FGR) using 5-aminolevulinic acid (5-ALA) exhibits a potential risk of permanent neurological deficits that can be minimized using intraoperative neurophysiological monitoring (IONM). We assessed the role of IONM in FGR surgery in patients harboring tumors in or near eloquent areas. IONM and FGR surgeries were performed on 34 ...
Massy Ziad A - - 2013
Lipid abnormalities and uremic toxins are features of chronic kidney disease (CKD) and may influence cardiovascular outcomes in CKD patients. Recent data suggest that uremic toxins may modulate lipoprotein levels and composition (e.g., oxidation or carbamylation) and enhance the cardiovascular toxicity of lipoproteins in CKD patients.
Suzuki Kazuo - - 2013
Myeloperoxidase (MPO)-specific antineutrophil cytoplasmic antibody (ANCA) is associated with rapidly progressive glomerulonephritis (RPGN) in microscopic polyangiitis (MPA). MPO-ANCA activates neutrophils by binding to cell surface MPO expressed on tumor necrosis factor-α (TNF-α)-primed neutrophils and induces neutrophil degranulation and production of reactive oxygen species, consequently resulting in glomerular endothelial damage. Recently, ...
Mair Johannes - - 2013
The clinical significance and economic impact of coronary artery disease has triggered major research efforts into the discovery of novel biomarkers for risk stratification in primary and secondary prevention and then the development of assays suitable for routine measurement. Nevertheless, the clinical impact of these novel biomarkers for risk stratification ...
Hu Lei - - 2013
The anti-HIV nucleoside lamivudine was asymmetrically synthesized in only three steps via a novel surfactant-treated subtilisin Carlsberg-catalyzed dynamic kinetic resolution protocol. The enantiomer of lamivudine could also be accessed using the same protocol catalyzed by Candida antarctica lipase B.
Zhu Xiao-Dong - - 2013
As diagnosis of nasopharyngeal carcinoma at an early disease stage is important, we attempted to distinguish between patients with nasopharyngeal carcinoma and noncancer controls by using serum protein profiles. Surface-enhanced laser desorption/ionization time-of-flight mass spectrometry and CM10 protein chip were used to detect the serum proteomic patterns of 65 patients ...
Borghei-Razavi Hamid - - 2013
Resection of the temporal bone to various degrees provides different levels of access to lesions of the posterior fossa. However, precise distances to the petrosal bone are still not clearly described. We evaluated the different distances of temporal bone landmarks in order to assess their variations and the possible correlations ...
Bi Yonghua - - 2013
Atherosclerosis, the leading cause of most cardiovascular disease, is a progressive multifaceted inflammatory disease characterized by extracellular matrix degradation and extensive remodeling of artery wall. However, its mechanism has not been completely understood, and animal models are useful to study its pathogenetic process. An analysis of literature on the nature ...
Kim Kyung Cheon - - 2013
The present study was performed to determine the translation of the glenohumeral joint in patients with and without shoulder lesions by comparing the magnetic resonance images obtained in the conventional adducted neutral rotation position with those obtained in the abducted externally rotated position. Two hundred and eighty-five consecutive shoulders without ...
Wolf Robert Christian - - 2013
Functional neuroimaging studies have reported task-related brain activation changes in preclinical individuals carrying the Huntington's disease (HD) gene mutation (preHD). Little is known about "task-negative" activity, i.e., patterns of task-related deactivation in preHD, and about the stability of any deactivation changes over the course of the disease. Here, we explored ...
Cadranel Alejandro - - 2013
A series of cyanide-bridged bimetallic compounds of the general formula [Ru(L)(bpy)(μ-NC)(M)](2-/-/2+) (L = tpy, 2,2'-6',2''-terpyridine, or tpm, tris(1-pyrazolyl)methane, bpy = 2,2'-bipyridine, M = Ru(II)(CN)5, Os(III)(CN)5, Os(II)(CN)5, Ru(II)(py)4(CN), py = pyridine) have been synthesized and fully characterized. Most of them present MLCT emission (λ = 690-730 nm, Φ = 10(-3)-10(-4)) and ...
Francois Jean Marie - - 2013
Over the past 20 years, the yeast cell wall has been thoroughly investigated by genetic and biochemical methods, leading to remarkable advances in the understanding of its biogenesis and molecular architecture as well as to the mechanisms by which this organelle is remodeled in response to environmental stresses. Being a dynamic ...
Herbst Sabine - - 2013
Calmodulin (CaM) is a highly conserved intracellular Ca(2+)-binding protein that exerts important functions in many cellular processes. Prominent examples of CaM-regulated proteins are adenylyl cyclases (ACs), which synthesize cAMP as a central second messenger. The interaction of ACs with CaM represents the link between Ca(2+)-signaling and cAMP-signaling pathways. Thereby, different ...
Ley-Quiñónez C P - - 2013
The concentration of heavy metals (Zn, Cd, Ni, Cu, Mn) and selenium (Se) was analyzed in blood collected from 12 black turtles (Chelonia mydas agasiizzi) captured in Canal del Infiernillo, Punta Chueca, Mexico. The most abundant metals were Zn (63.58 μg g(-1)) and Se (7.66 μg g(-1)), and Cd was the lower (0.99 μg g(-1)). The ...
Zhang Xue - - 2013
A demonstration of artificial groundwater recharge with tertiary effluent was evaluated using a set of bioassays (acute toxicity to Daphnia, genotoxicity, estrogenic and antiestrogenic toxicity). Around 95 % genotoxicity and 53 % antiestrogenicity were removed from the feed water by ozonation, whereas significant reduction of acute toxicity to Daphnia magna was achieved ...
Atasoy Ayse Dilek - - 2013
Endemic fluorosis affects millions of people worldwide. Fluorosis arises from the consumption of fluorine (F) contaminated water and was observed also in some parts of Turkey with volcanic rocks and geothermal resources. In the present study the removal of F from drinking water by raw and modified bauxite at the ...
Abuteen Akram - - 2013
Six free base tetrapyrrolic chromophores, three quinoline-annulated porphyrins and three morpholinobacteriochlorins, that absorb light in the near-IR range and possess, in comparison to regular porphyrins, unusually low fluorescence emission and (1)O2 quantum yields were tested with respect to their efficacy as novel molecular photo-acoustic imaging contrast agents in a tissue ...
Shinnabe Akihiro - - 2013
This study investigated the difference in clinical characteristics of fallopian canal dehiscence associated with pars flaccida and pars tensa cholesteatomas for the purpose of increasing the preoperative detectability of dehiscence. A total of 189 ears of patients 7-80 years of age (mean 42 years) with pars flaccida cholesteatoma and 63 ears of ...
Xu Yunfeng - - 2013
The present study identified some new important genomic regions and demonstrated the availability of conditional analysis in dissecting QTLs induced by environmental factors. The high input and low use efficiency of nutrient fertilizers require knowledge of the genetic control of crop reaction to nutrient supplements. In this study, 14 morphological ...
Fox Carolyn M - - 2013
The Rag2 region was frequently identified among 21 F 2 populations evaluated for soybean aphid resistance, and dominant gene action and single-gene resistance were also commonly identified. The soybean aphid [Aphis glycines Matsumura (Hemiptera: Aphididae)] is one of the most important insect pests of soybean [Glycine max (L.) Merr] in ...
Ellerkamp Verena - - 2013
Surgical approach to children with complicated ureteral duplication is discussed controversially. Our aim was to determine the outcome of children with complicated renal duplication undergoing a single-stage surgical approach with laparoscopic partial nephrectomy and open bladder reconstruction. Data of patients from 2004 to 2008 were investigated retrospectively. Outcome was analyzed ...
Park Ki Cheong - - 2013
New development in the vascular network is a significant process for the proliferation, as well as metastatic expand, of cancer cells that depends on a sufficient provider of oxygen and nutrients and the removal of waste products. New blood and lymphatic vessels form via step called angiogenesis and lymphangiogenesis. Angiogenesis ...
Gott Chloe - - 2013
Episodic thinking involves the ability to re-create past and to construct future personal events, which contain event-specific (episodic) and general (semantic) details. The richness of episodic thought for past events improves as children move into adolescence. The current study aims to examine changes in episodic future thinking and to establish ...
Zhang Lei - - 2013
Previous studies revealed that Se was an important regulatory factor for glutathione peroxidase (GPx) genes. However, the relationship between Se concentrations and mRNA expression levels of GPxs were unclear in goats, especially the goats living in natural Se-enriched area. Thus, the aim of this study was to determine the Se ...
Wang Jing - - 2013
To clarify the relationship between the soil selenium distribution and its bioavailability with the distribution of Kashin-Beck disease (KBD) endemic areas on the eastern edge of the Tibetan Plateau, samples of natural soil (0-20 cm), cultivated topsoil, and main crops of the region (highland barley) were collected at different altitudes according ...
Bae Insung - - 2013
Non-volatile ferroelectric-gate field effect transistors (Fe-FETs) memories with solution-processed ferroelectric polymers are of great interest due to their their potential for use in low cost flexible devices. In particular, the development of a process for patterning high performance semiconducting channel layers with mechanical flexibility is essential not only for proper ...
Zheng Leizhen - - 2013
Genome-wide association studies have reported a promising association of rs4072037 with gastric cancer (GC). This variant was associated with altered physiological function of MUC1 possibly by modulating promoter activity and alternative splicing of MUC1. However, the association results were inconclusive and estimate of the effect of this variant was not ...
Chung Jae Ho - - 2013
To evaluate the clinical and radiological features and the risk of middle ear disease in the contralateral ears of unilateral cholesteatoma with clinical and radiological assessment. Fifty-two patients with unilateral cholesteatoma and 30 control subjects underwent otoscopic and audiologic examination. Temporal bone computed tomography was performed to evaluate the pneumatization ...
Spiteri A V - - 2013
PurposeTraining within a proficiency-based virtual reality (VR) curriculum may reduce errors during real surgical procedures. This study used a scientific methodology to develop a VR training curriculum for phacoemulsification surgery (PS).Patients and methodsTen novice-(n) (performed <10 cataract operations), 10 intermediate-(i) (50-200), and 10 experienced-(e) (>500) surgeons were recruited. Construct validity ...
Leibovich Tali - - 2013
The approximate number system (ANS) theory suggests that all magnitudes, discrete (i.e., number of items) or continuous (i.e., size, density, etc.), are processed by a shared system and comply with Weber's law. The current study reexamined this notion by comparing performance in discrete (comparing numerosities of dot arrays) and continuous ...
Maffei Giulia - - 2013
The arbuscular mycorrhizal (AM) symbiosis is considered a natural instrument to improve plant health and productivity since mycorrhizal plants often show higher tolerance to abiotic and biotic stresses. However, the impact of the AM symbiosis on infection by viral pathogens is still largely uncertain and little explored. In the present ...
Nixdorff Kathryn - - 2013
Advances in the life sciences are occurring with extreme rapidity and accumulating a great deal of knowledge about life's vital processes. While this knowledge is essential for fighting disease in a more effective way, it can also be misused either intentionally or inadvertently to develop novel and more effective biological ...
Parra-Herran Carlos E - - 2013
When classifying cellular uterine mesenchymal neoplasms, histological distinction of endometrial stromal from smooth muscle neoplasms can be difficult. The only widely established marker of endometrial stromal differentiation, CD10, has marginal specificity. We took a bioinformatics approach to identify more specific markers of endometrial stromal differentiation by searching the Human Protein ...
Torche Fayçal - - 2013
The diethylcarbonate, DEC, is an ester that is used as a solvent in Li-ion batteries but its behavior under ionizing radiation was unknown. The transient optical absorption spectra, the decay kinetics, and the influence of various scavengers have been studied by using the picosecond laser-triggered electron accelerator ELYSE. In neat ...
Wang Shanquan - - 2013
Wastewater treatment plants (WWTPs) are major collection pools of antibiotics of which low concentrations may induce antibiotic resistance in their microbial communities and pose threat to human health. However, information is still limited on the microbial community alteration in WWTPs upon exposure to low-dose antibiotics due to absence of negative ...
Singh Surjit - - 2013
Although Kawasaki disease (KD) is now being increasingly reported from India, the vast majority of children with KD are still not being diagnosed and treated. A recent study from Chandigarh has shown that the incidence of KD is at least 4.54/100,000 children below 15 y of age. Extrapolations of this figure ...
Fukunaga Keisuke - - 2013
The site-specific introduction of a haloacetamide derivative into a designated cysteine on a displaying peptide on a capsid protein (gp10) of bacteriophage T7 has been achieved. This easiest gp10-based thioetherification (10BASEd-T) is carried out in one-pot without side reactions or loss of phage infectivity.
Kieffer James D - - 2013
This study examined the effects of acclimation temperature (10, 15, 20, or 25 °C) and an acute exposure to various temperatures on the routine metabolism of juvenile (~11 g) shortnose sturgeon (Acipenser brevirostrum). For the acclimation experiment, the minimum, mean, and maximum routine metabolic rates were established for sturgeon at each temperature. ...
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