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Results 351 - 400 of 4535
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Zhou Xiongtu - - 2013
High-quality tetrapod-shaped Sn-doped ZnO (T-SZO) nanostructures have been successfully synthesized via thermal evaporation of mixed Zn and Sn powder. The effects of Sn dopant on the morphology, microstructure, optical and field emission (FE) properties of T-SZO were investigated using scanning electronic microscopy (SEM), X-ray diffraction (XRD), transmission electron microscopy (TEM), ...
Ostergaard Leif - - 2013
The mortality after aneurysmal subarachnoid hemorrhage (SAH) is 50%, and most survivors suffer severe functional and cognitive deficits. Half of SAH patients deteriorate 5 to 14 days after the initial bleeding, so-called delayed cerebral ischemia (DCI). Although often attributed to vasospasms, DCI may develop in the absence of angiographic vasospasms, ...
Gong Qiyong - - 2013
Neuroimaging techniques hold the promise that they may one day aid the clinical assessment of individual psychiatric patients. However, the vast majority of studies published so far have been based on average differences between groups. This study employed a multivariate approach to examine the potential of resting-state functional Magnetic Resonance ...
Kimber Ian - - 2013
Abstract There is considerable interest in the immunobiological processes through which the development of allergic sensitization to chemicals is initiated and orchestrated. One of the most intriguing issues is the basis for the elicitation by chemical sensitizers of different forms of allergic reaction; that is, allergic contact dermatitis or sensitization ...
Schopfer Kurt - - 2013
This study aimed at determining the sensitivity of a whole blood interferon-γ release assay (IGRA) among children with microbiologically confirmed tuberculosis in a high-burden country. Children with a diagnosis of tuberculosis based on clinical and radiographic assessment were tested with an IGRA in addition to microbiologic examination of appropriate specimens ...
Butler Randall T - - 2013
Salivary duct carcinoma is a highly aggressive salivary gland malignancy that may be misdiagnosed as high-grade mucoepidermoid carcinoma. We utilized tissue microarrays with 78 examples of mucoepidermoid carcinoma and 47 salivary duct carcinomas to evaluate the utility of an immunohistochemical panel consisting of androgen receptor, Her2/neu, p63, and cytokeratin 5/6 ...
Wei Wei - - 2013
The first copper-catalyzed oxysulfonylation reaction of alkenes with dioxygen and sulfonylhydrazides for the construction of β-ketosulfones has been developed under mild conditions without any ligand or additive.
Accart Nathalie - - 2013
Primary cutaneous lymphomas (CLs), characterized by an accumulation of clonal T or B lymphocytes preferentially localized in the skin, have been successfully treated with interferons (IFNs) which counterbalance the Th2-immunosuppressive state associated with this pathology. In a phase I/II clinical trial, we correlated the local immune infiltrate and the anti-tumor ...
- - 2013
In a randomised controlled trial, researchers in Australia explored whether the provision of rapid HIV testing to men who have sex with men, with results available within 20 minutes of a blood test, would increase their frequency of testing over time.
Adams Michael - - 2013
At the beginning of your nursing career, remember that being a caring and compassionate nurse is an absolute priority. Studying for a degree does not change this - in fact, a better education should enhance these skills.
Zhao Ying - - 2013
Assembly of 5-nitro-1,2,3-benzenetricarboxylic acid (H3nbta) with Cu(II) in the presence of 1,3-bis(1,2,4-triazol-1-yl)propane (1,3-btp) leads to a new metal-organic framework, [Cu(Hnbta)(1,3-btp)]·2H2O (), which is shown to be an efficient and recyclable heterogeneous catalyst for enamination of β-ketoesters with excellent product yields and selectivity.
Altunkaya Arzu - - 2013
Grape seed extract (GSE), a by-product from the wine industry, was explored for its use as enrichment to mayonnaise, due to its potential health effects. Mayonnaises were enriched with 0 mg GSE per mL, 0.5 mg GSE per mL (∼0.050%), 0.9 mg GSE per mL (∼0.10%) and 1.4 mg GSE ...
Anderson Stacey E - - 2013
Abstract Allergic disease is an important occupational health concern, with work-related asthma and allergic contact dermatitis being the most frequently diagnosed occupational illnesses. Diisocyanates, particularly toluene 2,4-diisocyanate (TDI), have been the leading cause of occupational asthma for many years. Understanding the mechanisms behind allergic disease is critical for treatment and ...
Scurr M - - 2013
Although elevated CD4(+)Foxp3(+) regulatory T cell (Treg) frequencies within tumors are well documented, the functional and phenotypic characteristics of CD4(+)Foxp3(+) and CD4(+)Foxp3(-) T cell subsets from matched blood, healthy colon, and colorectal cancer require in-depth investigation. Flow cytometry revealed that the majority of intratumoral CD4(+)Foxp3(+) T cells (Tregs) were Helios(+) ...
Melero Yolanda - - 2013
Trophic relationships between invasive species in multiply invaded ecosystems may reduce food limitation relative to more pristine ecosystems and increase resilience to control. Here, we consider whether invasive predatory American mink Neovison vison are trophically subsidized by invasive crayfish. We collated data from the literature on density and home range ...
Suh Min Hee - - 2013
To compare the diagnostic ability of optic disc rim area (RA), retinal nerve fiber layer thickness (RNFLT), and their combination on sector-based analysis of spectral domain optical coherence tomography (Cirrus OCT) in discriminating subjects with early-stage open angle glaucoma (OAG) from normal subjects. RA and RNFLT of 78 early OAG ...
Chaar Ines - - 2013
One of the most important pathways which are frequently affected in colorectal cancer is p53/ (MDM2)/p14ARF pathway. We aim to determine the methylation pattern of p14/ARF in relation to mutation of p53. This correlation was studied to investigate whether their alterations could be considered as a predictor factor of prognosis ...
Schellekens Huub H Department of Pharmaceutical Sciences, Utrecht University, P.O. Box 80.082, 3508 TB, Utrecht, The Netherlands, - - 2014
The aim of this critical review is to reach a global consensus regarding the introduction of follow-on versions of nonbiological complex drugs (NBCD). A nonbiological complex drug is a medicinal product, not being a biological medicine, where the active substance is not a homo-molecular structure, but consists of different (closely ...
Miah Mohammad K - - 2013
To investigate the effects of normothermic hepatic ischemia-reperfusion (IR) injury on the activity of P-glycoprotein (P-gp) in the liver and at the blood-brain barrier (BBB) of rats using rhodamine 123 (RH-123) as an in vivo marker. Rats were subjected to 90 min of partial ischemia or sham surgery, followed by 12 ...
Lane-Degraaf Kelly E - - 2013
Landscape complexity can mitigate or facilitate host dispersal, influencing patterns of pathogen transmission. Spatial transmission of pathogens through landscapes, therefore, presents an important but not fully elucidated aspect of transmission dynamics. Using an agent-based model (LiNK) that incorporates GIS data, we examined the effects of landscape information on the spatial ...
Chen Xiaoqiu - - 2013
This work was undertaken to examine the combined effect of air temperature and precipitation during late winter and early spring on modeling greenup date of grass species in the Inner Mongolian Grassland. We used the traditional thermal time model and developed two revised thermal time models coupling air temperature and ...
Han Sang Myung - - 2013
Patients with aneurysmal subarachnoid hemorrhage (SAH) frequently have deficits in learning and memory that may or may not be associated with detectable brain lesions. We examined mediators of long-term potentiation after SAH in rats to determine what processes might be involved. There was a reduction in synapses in the dendritic ...
Civile Ciro - - 2013
The face inversion effect (FIE) is a reduction in recognition performance for inverted faces (compared to upright faces) that is greater than that typically observed with other stimulus types (e.g., houses). The work of Diamond and Carey, suggests that a special type of configural information, "second-order relational information" is critical ...
- - 2013
School nurses and health visitors have been urged to 'think the unthinkable' and consider that children presenting with problems may be experiencing abuse.
Haavik H - - 2013
The aim of this study was to investigate the effect of varying stimulation rate and the effects of a repetitive typing task on the amplitude of somatosensory evoked potential (SEP) peaks thought to relate to cerebellar processing. SEPs (2,000 sweep averages) were recorded following median nerve stimulation at the wrist ...
Goovaerts Vincent - - 2013
The interaction between the plenary Keggin H3PW12O40, lacunary Keggin K7PW11O39 and the Eu(iii)-substituted Keggin K4EuPW11O39 (Eu-Keggin) type polyoxometalates (POMs), and the proteins human and bovine serum albumin (HSA and BSA) was studied using steady state and time-resolved Eu(iii) luminescence and tryptophan (Trp) fluorescence spectroscopy. The excitation spectrum of the Eu-Keggin ...
- - 2013
Fewer than a third of people in the UK are aware of the health complications associated with type 2 diabetes including blindness, heart attack and stroke, a charity has warned.
Travis Mike - - 2013
Peter Cheese, chief executive of the Chartered Institute of Personnel and Development, says that zero-hours contracts, when used appropriately, can provide flexibility for employers and employees alike (Letters September 18). But he sits on the fence with regard to zero-hours contracts in the NHS and fails to address any criticism ...
Li Min - - 2013
Previous studies have shown that lipopolysaccharide (LPS) can upregulate MUC5AC in airway epithelial cells. However, the relationship and mechanism between bacterial infection and altered mucus secretion in the biliary tract remains unclear. Human biliary epithelial cells were induced by LPS, H2O2 production in the cell supernatants were detected by specific ...
Vartanian Lenny R - - 2013
Emotions form an important part of stereotyping and prejudice, but little is known about how intergroup emotions are associated with anti-fat prejudice. This study examined the relation between negative intergroup emotions (disgust, contempt, and anger) and the stereotypes of obese people. A community sample (n = 380) and an undergraduate sample (n = 96) ...
Csont Tamás - - 2013
Although complex multivitamin products are widely used as dietary supplements to maintain health or as special medical food in certain diseases, the effects of these products were not investigated in hyperlipidemia which is a major risk factor for cardiovascular diseases. Therefore, here we investigated if a preparation developed for human ...
Pick David F - - 2013
Prior studies have shown that a left-right spatial compatibility effect occurs for vertically oriented stimuli relative to a background context of a face rotated 90° clockwise or counterclockwise from upright. For stimuli presented at the location of the eyes, the mapping of the right eye to a right response and ...
Matteson Lindsay K LK Minnesota Center for Twin and Family Research, Department of Psychology, University of Minnesota, Elliott Hall, 75 E River Pkwy, Minneapolis, MN, 55455, USA, - - 2013
In the past, shared environmental influences on personality traits have been found to be negligible in behavior genetic studies (e.g., Bouchard and McGue, J Neurobiol 54:4-45, 2003). However, most studies have been based on biometrical modeling of twins only. Failure to meet key assumptions of the classical twin design could ...
Kwon Jae Won - - 2013
Bacillus subtilis JW-1 was isolated from rhizosphere soil as a potential biocontrol agent of bacterial wilt caused by Ralstonia solanacearum. Seed treatment followed by a soil drench application with this strain resulted in > 80% reduction in bacterial wilt disease compared with that in the untreated control under greenhouse conditions. ...
Salvage Jane - - 2013
Nurses get so much bad press these days that it is a rare pleasure to be reminded of their many virtues. Heroism is the right description for what so many nurses do, day in day out, never more so than in wartime.
Lee Kyu-Shik - - 2013
We investigated the effects of starfish (Asterina pectinifera) polysaccharides on metastatic activity in MCF-7 estrogen receptor (ER)-positive human breast cancer cells. In wound healing assay, 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced cell migration was dose-dependently decreased by the starfish polysaccharides (PS). Transcription of aromatase, which catalyzes estrogen synthesis from androgen, was reduced by PS. ...
Deedwania Prakash - - 2013
Heart rate is an important contributor in the pathophysiology of both coronary artery disease (CAD) and heart failure (HF). Ivabradine is an anti-anginal and anti-ischaemic agent, which selectively and specifically inhibits the I f current in the sino-atrial node and provides pure heart rate reduction without altering other cardiac parameters, ...
Dag Ilknur - - 2013
The objective of the study was to investigate biofilm formation on Merocel(®) and silicone nasal splint after nasal septal surgery. 50 patients who were scheduled to undergo nasal septal surgery were included in this study. The patients were randomized into receiving an insert of Merocel(®) or silicone splint after septoplasty. ...
Liu Xingrong - - 2013
This study was to characterize the pharmacokinetics (PK) and pharmacodynamics (PD) of a chimeric protein, CD4-anchoring bi-functional fusion inhibitor (CD4-BFFI), in monkeys and assess the feasibility for HIV-1 treatment in humans. The serum concentrations of CD4-BFFI and CD4 receptors were determined and modeled using a target-mediated drug disposition (TMDD) model ...
Woodson Benjamin - - 2013
Objective To assess application of cystatin C and NGAL as biomarkers for renal ischemic injury. We also evaluated the use of allopurinol as a renoprotective agent. A second goal was to assess cystatin C as a biomarker in patients undergoing partial nephrectomy. Materials and Methods Using 58 Sprague-Dawley rats, we ...
Herscovici Dolfi D - - 2013
Nailing comminuted femur fractures may result in leg shortening, producing significant complications including pelvic tilt, narrowing of the hip joint space, mechanical and functional changes in gait, an increase in energy expenditures, and strains on spinal ligaments, leading to spinal deformities. The frequency of this complication in patients managed with ...
Viberg Jennifer - - 2013
Incidental findings (IFs) are acknowledged to be among the most important ethical issues to consider in biobank research. Genome-wide association studies and disease-specific genetic research might reveal information about individual participants that are not related to the research purpose, but may be relevant to those participants' future health. In this ...
Rupp Thomas - - 2013
This study investigated the changes in cerebral near-infrared spectroscopy (NIRS) signals, cerebrovascular and ventilatory responses to hypoxia and CO2 during altitude exposure. At sea level (SL), after 24 hours and 5 days at 4,350 m, 11 healthy subjects were exposed to normoxia, isocapnic hypoxia, hypercapnia, and hypocapnia. The following parameters were measured: ...
- - 2013
Care for hip fracture patients is improving, with 86 per cent of patients receiving surgery within 48 hours of hospital admission and 94 per cent having a falls assessment before discharge.
Arif Zeba - - 2013
The health select committee has called on hospitals in England to display publicly the number of nurses on duty on each ward. The committee members say this would lead to greater openness and would help to increase trust in the NHS.
Walter Annette O - - 2013
Non-small cell lung cancer (NSCLC) patients with activating epidermal growth factor receptor (EGFR) mutations initially respond to first generation reversible EGFR tyrosine kinase inhibitors. However, clinical efficacy is limited by acquired resistance, frequently driven by the EGFR T790M mutation. CO-1686 is a novel, irreversible and orally delivered kinase inhibitor that ...
Vult von Steyern Kristina K Center for Medical Imaging and Physiology, Skåne University Hospital, Lund, Lund University, 221 85, Lund, Sweden, - - 2013
The first radiographic scoring system for pulmonary cystic fibrosis was presented in 1958. Since then a multitude of scoring systems for radiography and computed tomography (CT) have been presented, recently also for tomosynthesis and magnetic resonance imaging (MRI). The aim of the current review was to analyse and compare the ...
Chang Chong Bum - - 2013
Information on the coexistence of lumbar spondylosis and its influence on overall levels of pain and function in patients with advanced knee osteoarthritis (OA) undergoing total knee arthroplasty (TKA) would be valuable for patient consultation and management. The purposes of this study were to document the prevalence and severity of ...
Jayasiri H B - - 2013
Nine metals were monitored in the beach sediment in Mumbai from May 2011 to March 2012 to evaluate the spatial and temporal distributions. The average heavy metal concentrations exhibited the following order: Fe > Mn > Cr > Co > Ni > Pb > Zn > Cu > Cd for ...
Chatsuriyawong Siriporn - - 2013
The presence of endothelial dysfunction (ED) constitutes an early risk factor for cardiovascular disease (CVD) in children. Nitric oxide (NO) and endothelin (EDN) are generated in endothelial cells and are critical regulators of vascular function, with ED resulting from an imbalance between these two molecules. We hypothesized that genetic variants ...
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