Search Results
Results 201 - 250 of 4474
< 1 2 3 4 5 6 7 8 9 10 >
Bennetts Brett - - 2013
Uniquely, the ClC family harbours dissipative channels and anion/H(+) transporters that share unprecedented functional characteristics. ClC-1 channels are homodimers in which each monomer supports an identical pore carrying three anion-binding sites. Transient occupancy of the extracellular binding site by a conserved glutamate residue, E232, independently gates each pore. A common ...
Li Wei-Zhen - - 2013
The development of thermally stable, nanometer-sized precious metal-based catalysts remains a daunting challenge. Such materials, especially those based on the use of costly platinum metal, are essential and, to date, non-replaceable for a large number of industrially important catalytic processes. Here we report a well-defined cuboctahedral MgAl2O4 spinel support material ...
Rhodes Lesley - - 2013
This review article outlines harmful algal bloom (HAB) monitoring practices in New Zealand and highlights the shift from light microscope (LM)-based identification and quantification of the early 1990s to the use of molecular tools to support the HAB monitoring programmes two decades later. Published research and available client information from ...
Gillen Sally - - 2013
The RCN is calling for swift action to implement a recommendation on safe staffing by Robert Francis in his report on care failings at Mid Staffs.
Trueland Jennifer - - 2013
Nurses should be trained in recognising vision problems in patients following an acute stroke, according to guidance launched last week.
Keogh Kat - - 2013
Each year, front line NHS staff are offered a free seasonal flu vaccination to help protect them and their patients from picking up the virus.
Arif Zeba - - 2013
The health select committee has called on hospitals in England to display publicly the number of nurses on duty on each ward. The committee members say this would lead to greater openness and would help to increase trust in the NHS.
Stockwell Felicity - - 2013
I write in support of Benny Goodman's letter (September 18) questioning if revalidation can make any difference in improving nursing standards.
- - 2013
An interim suspension order was made against me at a Nursing and Midwifery Council (NMC) fitness to practise hearing recently and I was suspended from the register.
Bannister Richard - - 2013
Starting a three-year nursing programme is an exciting, yet daunting, time for most new students. This is especially true for mature students who may be entering higher education after many years away from any kind of study.
Carson Pauline - - 2013
Simulation learning is used in several health disciplines. The Department of Health defines simulation as 'any reproduction or approximation of a real event, process or set of conditions or problems'.
Ashby Sue - - 2013
Many people who have experienced health care are supporting nurse education programmes by informing students about their experiences and how their needs can be best met by healthcare professionals.
Humphries Belinda - - 2013
Practice experiences can be among the most memorable, enjoyable and rewarding times for students embarking on their nursing careers. They can also be thought-provoking, pressurised and challenging.
Neenan Trudi - - 2013
Part of my lecturer role involves helping students to gain confidence in numeracy.
Hsu Po-Chun - - 2013
For transparent conducting electrodes in optoelectronic devices, electrical sheet resistance and optical transmittance are two of the main criteria. Recently, metal nanowires have been demonstrated to be a promising type of transparent conducting electrode because of low sheet resistance and high transmittance. Here we incorporate a mesoscale metal wire (1-5 μm ...
Travis Mike - - 2013
Peter Cheese, chief executive of the Chartered Institute of Personnel and Development, says that zero-hours contracts, when used appropriately, can provide flexibility for employers and employees alike (Letters September 18). But he sits on the fence with regard to zero-hours contracts in the NHS and fails to address any criticism ...
Bethel James - - 2013
The assessment of suicidal intent in first-contact settings, including the emergency department, can be challenging. Inaccurate assessment can lead to increased incidence of self-harm and completion of suicide. This article focuses on factors that may affect review of this patient group, including healthcare professionals' personal and professional standards and values. ...
Morrow Abby - - 2013
Mental and physical health are intrinsically linked to a person's ability to maintain good physical health determined, in part, by his or her mental wellbeing. Similarly, poor physical health can lead to mental health problems.
Singh Shalini - - 2013
Homogenously alloyed CdSexS1-x nanorods with controlled aspect ratios are synthesised by a hot-injection colloidal route. The optical absorption and photoluminescence emission are compositionally tunable with chalcogen ratios. The synthetic protocol is sufficiently robust to allow good control of rod aspect ratios, with low polydispersities, suited for their rational assembly into ...
Zhao Ying - - 2013
Assembly of 5-nitro-1,2,3-benzenetricarboxylic acid (H3nbta) with Cu(II) in the presence of 1,3-bis(1,2,4-triazol-1-yl)propane (1,3-btp) leads to a new metal-organic framework, [Cu(Hnbta)(1,3-btp)]·2H2O (), which is shown to be an efficient and recyclable heterogeneous catalyst for enamination of β-ketoesters with excellent product yields and selectivity.
Ko Hae Young - - 2013
NIRF imaging of carbon nanodots derived from tire soot was clearly visualized in glioma in vitro and in vivo.
Sun Hua - - 2013
A silicon nanoparticle solution (size ≅ 50 nm) with the concentration of 100 mM, which is contamination free, was synthesized using a ball milling method and was stable for 4 months without aggregation. This stability was responsible for large negative zeta potential on the surface of Si-NPs, established by milling ...
Denaro Nerina - - 2013
Treatment of unresectable, locally advanced head and neck cancer consists of many different options, all of them based on radiotherapy. The main variable is represented by chemotherapy, i.e., the way in which chemotherapy is combined with radiation. More recently, the combination of cetuximab and radiotherapy emerged as a new treatment ...
Parsons Sheena M A - - 2013
Animal body size often varies systematically along latitudinal gradients, where individuals are either larger or smaller with varying season length. This study examines ecotypic responses by the generalist grasshopper Melanoplus femurrubrum (Orthoptera: Acrididae) in body size and covarying, physiologically based life history traits along a latitudinal gradient with respect to ...
Melero Yolanda - - 2013
Trophic relationships between invasive species in multiply invaded ecosystems may reduce food limitation relative to more pristine ecosystems and increase resilience to control. Here, we consider whether invasive predatory American mink Neovison vison are trophically subsidized by invasive crayfish. We collated data from the literature on density and home range ...
Cocco Emiliano - - 2013
Doxorubicin (DOX) is an anticancer drug with cardiotoxic side effects mostly caused by iron homeostasis dysregulation. Mitochondria are involved in iron trafficking and mitochondrial ferritin (FtMt) was shown to provide protection against cellular iron imbalance. Therefore, we hypothesized that FtMt overexpression could limit DOX effects on iron homeostasis. Heart's homogenates ...
Liao Weiyong - - 2013
Cross-sectional studies have demonstrated a reverse relationship between serum level of testosterone (T) and the incidence rate of cardiovascular disease in men, indicating that T exerts beneficial effects in cardiovascular system. However, the endothelial effects of T are poorly understood. Actin remodeling is essential for endothelial cell movement and vascular ...
Rudnicka Helena - - 2013
BRCA1 and BRCA2 are two major genes associated with familial breast and ovarian cancer susceptibility. In Poland standard BRCA gene test is usually limited to Polish founder BRCA1 mutations: 5382insC, C61G and 4153delA. To date, just a few single large genomic rearrangements (LGRs) of BRCA1 gene have been reported in ...
Sun Rongbin - - 2013
Rheumatoid arthritis (RA) and ankylosing spondylitis (AS) are autoimmune, inflammatory diseases with substantial genetic contributions. Matrix metalloproteinase (MMP)-2, tumor necrosis factor (TNF)-α and NLR family pyrin domain-containing 1 (NLRP1) play important roles in the immune response. We studied the MMP-2 rs243865 C/T, TNF-α rs1800629 A/G, NLRP1 rs878329 C/G and NLRP1 ...
Zhang Hong - - 2013
The non-protein-coding genes have been reported as a critical control role in the regulation of gene expression in abiotic stress. We previously identified four expressed sequence tags numbered S18 (EL773024), S73 (EL773035), S106 (EL773041) and S108 (EL773042) from a SSH-cDNA library of bread wheat Shaanmai 139 infected with Puccinia striiformis ...
Wu Ying - - 2013
The serotonin 2A (5-HT2A) receptor has been implicated in obstructive sleep apnea (OSA). Single nucleotide polymorphisms (SNPs) in the 5-HT2A gene have been found in OSA, the most common being -1438G/A and T102C; however, studies of the association between 5-HT2A SNPs and OSA risk have reported inconsistent findings. A meta-analysis ...
Zhang Ru - - 2013
In order to screen novel genes involved in the biosynthesis and accumulation of ginsenosides in ginseng for investigating the molecular mechanism of ginsenosides accumulation, the differential expression analysis was performed by cDNA-amplified fragment length polymorphism (cDNA-AFLP) in methyl jasmonate (MeJA) treated ginseng suspension cells and untreated controls. Twenty-five transcript-derived-fragments (TDFs) ...
Shen Fang-Fang - - 2013
Cytochrome P4501A1 (CYP1A1) enzyme is a member of the CYP superfamily of enzymes. CYP1A1 A2455G and T3801C are two most commonly studied polymorphisms loci. Previous studies have reported that CYP1A1 polymorphisms increase esophageal cancer (EC) risk. However, the results remain controversial and ambiguous. To further investigate the association between CYP1A1 ...
Polakova Vymetalkova Veronika - - 2013
Altered expression and methylation pattern of tumor suppressor and DNA repair genes, in particular involved in mismatch repair (MMR) pathway, frequently occur in primary colorectal (CRC) tumors. However, little is known about (epi)genetic changes of these genes in precancerous and early stages of CRC. The aim of this pilot study ...
Kim In Sik - - 2013
We investigated the effect of asthmatic serum on constitutive eosinophil apoptosis in normal subjects. Eosinophil apoptosis in normal subjects was inhibited by asthmatic serum but not normal serum. In a detailed analysis based on the presence of house dust mite (HDM) IgE, HDM IgE-positive (+) asthmatic serum was more effective ...
Zhang Xiao-Yan - - 2013
In the current study, we measured urinary angiotensinogen (AGT) through enzyme-linked immunoadsordent assay (ELISA) and analyzed its correlation with intrarenal renin-angiotensin system (RAS) activity in 128 chronic kidney disease (CKD) patients. Urinary and plasma renin activity, AGT, angiotensin II (Ang II) and aldosterone levels were also measured by radioimmunoassay (RIA) ...
Jamali Samad - - 2013
Desert truffles, hypogeous Pezizales (Ascomycota), are difficult to identify due to evolutionary convergence of morphological characters among taxa that share a similar habitat and mode of spore dispersal. Also, during their symbiotic phase, these are barely distinguishable morphologically, and molecular probes are needed for their identification. We have developed a ...
Uddin Raza Mohy - - 2013
Prolactin (PRL) is a polypeptide hormone, secreted mainly by the anterior pituitary gland. It is involved in many endocrine activities. The key functions of PRL are related to reproduction and lactation in mammals. To ascertain the presence of polymorphisms in the bovine PRL gene (bPRL), the bPRL gene was sequenced. ...
Zhu Lingling - - 2013
Accumulating evidence suggests that microRNAs (miRNAs) play an important role in regulating the pathways in adipose tissue that control processes such as adipogenesis, insulin resistance, and inflammation. MiR-143 is a well-characterized miRNA involved in adipogenesis and may be involved in regulating insulin resistance. Free fatty acids (FFAs) and adipokines, such ...
Qin Li-Sen - - 2013
Primary glioblastoma multiforme is the most malignant form of astrocytic tumor with an average survival of approximately 12-14 months. The combination of novel Akt inhibitors with anti-cancer therapeutics has achieved improved anti-tumor efficiency. In the current study, we examined the synergistic anti-cancer ability of Akt inhibitor perifosine in combination with short-chain ...
Niu Fubiao - - 2013
MYH3, whose function is to convert chemical energy to mechanical energy through ATP hydrolysis, is mainly expressed in skeletal muscle at various stages and is indispensable in the procedure of development of skeletal muscle and heart. In the study, genetic variations and genotypes of MYH 3 gene in a total ...
Yamashita Saori - - 2013
Background: Thymic stromal lymphopoietin (TSLP) plays critical roles in the induction and exacerbation of allergic diseases. We tested various chemicals in the environment and found that xylene and 1,2,4-trimethylbenzene induced the production of TSLP in vivo. These findings prompted us to search for additional chemicals that induce TSLP production. In ...
Takahashi Aya - - 2013
Background: Eczema in the cubital fossa, which is susceptible to sweat, is frequently observed in atopic dermatitis (AD). However, there has been no direct evidence that sweating causes eczema in the cubital fossa. Methods: To investigate this issue, axon reflex-mediated sweating volume (AXR) and skin barrier function in the cubital ...
Tateishi Ukihide - - 2013
Coregistered fluorine-18-fluorodeoxyglucose positron emission tomography/computed tomography (PET/CT) provides functional and morphologic data useful for the management of lymphoma. PET/CT is a promising tool in initial staging/re-staging, monitoring post-treatment recurrence/exacerbation, and evaluating prognosis at mid-treatment use [interim PET/CT (iPET/CT)]. Many multicenter studies are currently underway to investigate the effectiveness and safety ...
Cvetko Erika - - 2013
The inferior alveolar nerve block is one of the most common techniques for delivering dental anesthesia. Its success depends on placing the needle tip in close proximity to the mandibular foramen (MF). In certain cases, however, this nerve block fails, even when performed by the most experienced clinician. Anatomical variability ...
Magro Elsa - - 2013
Anatomic arrangement of venous system within the transverse foramen is a controversial topic among authors. Precise knowledge of this arrangement is necessary in imaging where vertebral artery dissection is suspected, as well as in surgical approaches of cervical spine. This knowledge objective cannot be achieved without a prerequisite knowledge of ...
Zeiler Kristin - - 2013
Since John Locke, regnant conceptions of personhood in Western philosophy have focused on individual capabilities for complex forms of consciousness that involve cognition such as the capability to remember past events and one's own past actions, to think about and identify oneself as oneself, and/or to reason. Conceptions of personhood ...
Schopfer Kurt - - 2013
This study aimed at determining the sensitivity of a whole blood interferon-γ release assay (IGRA) among children with microbiologically confirmed tuberculosis in a high-burden country. Children with a diagnosis of tuberculosis based on clinical and radiographic assessment were tested with an IGRA in addition to microbiologic examination of appropriate specimens ...
McCarty-Caplan David - - 2013
This study examined patterns of drug use among gay men and other men who have sex with men (MSM) to identify sub-categories of men whose drug use and sexual behavior place them at especially high risk for HIV. A latent class analysis of a sample of MSM yielded a four-class ...
Scott Hyman M - - 2013
Resiliency factors such as social support have been associated with more frequent HIV testing among MSM. We examined the association between social support and delayed HIV testing in the context of structural discrimination and individual factors among young Black MSM. We combined two independent cross-sectional samples recruited 1 year apart from ...
< 1 2 3 4 5 6 7 8 9 10 >