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Results 201 - 250 of 4535
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Wang Shengman - - 2013
Heavy metal pollution and soil acidification are serious global environmental issues. The combined pollution from acidification and heavy metal has become a new environmental issue in regions where the two issues simultaneously occur. However, studies on combined pollution are still limited. In the current study, we investigated the combined effect ...
Huang Wen - - 2013
Elevated thyrotropin (TSH) and hypercholesterolemia commonly coexist in patients with subclinical hypothyroidism, which can cause and aggravate heart disease. However, it is unclear whether TSH has a direct effect on cardiac function. To determine the expression of the thyrotropin receptor (TSHR) and the effects of TSH on ventricular function, we ...
Markov Dmitry A - - 2013
Polydimethylsiloxane (PDMS) is a commonly used polymer in the fabrication of microfluidic devices due to such features as transparency, gas permeability, and ease of patterning with soft lithography. The surface characteristics of PDMS can also be easily changed with oxygen or low pressure air plasma converting it from a hydrophobic ...
Esposito Katherine - - 2013
Metabolic syndrome has become a major public health problem worldwide and represents a common clinical condition in countries with a high incidence of obesity and western dietary patterns. Metabolic syndrome associates with common cancers at many sites, including liver, colorectal, and bladder cancers in men, and endometrial, pancreatic, breast post-menopausal, ...
- - 2013
A planned £9.9 million NHS spending cut for next year will hamper nurses efforts to control hospital-acquired infections, RCN Scotland has warned.
- - 2013
This brilliant book reflects on a time of dreadful loss and tragedy on a scale that is now difficult to comprehend. It offers the personal accounts of nurses of all grades and disciplines, and in many locations.
Rudnicka Helena - - 2013
BRCA1 and BRCA2 are two major genes associated with familial breast and ovarian cancer susceptibility. In Poland standard BRCA gene test is usually limited to Polish founder BRCA1 mutations: 5382insC, C61G and 4153delA. To date, just a few single large genomic rearrangements (LGRs) of BRCA1 gene have been reported in ...
de Bruin Rick - - 2013
Endoscopic surgery of the skull base has been on the rise for several years. Endoscopic access for surgery can be achieved from the frontal sinus anteriorly along the skull base to the odontoid process posterior inferiorly. An endoscope is inserted through one nasal corridor and allows visualization of the working ...
Le Guellec Sandrine - - 2013
Intranasal deposition of aerosols is often studied using in vitro nasal cavity models. However, the relevance of these models to predict in vivo human deposition has not been validated. This study compared in vivo nasal aerosol deposition and in vitro deposition in a human plastinated head model (NC1) and its ...
Dubey Archana - - 2013
We have determined the structure and coordination chemistry of rhizoferrin (Rf), which is a particular type of siderophore, and its Fe(III) complexes using density functional theory calculations. Our results show that the Fe(III) ion binds in an octahedral coordination, with a low-spin (S = 1/2) charge-neutral chiral complex having the largest binding ...
Shokrollahi Ardeshir - - 2013
In this study, cloud point extraction was used for the preconcentration of Al(3+) ion after the complex formation with 1,4-dihydroxy-9,10-anthraquinone (Quinizarin [QUIN]), and subsequent analysis by spectrophotometeric method, using Triton X-114 as surfactant. The optimal extraction and reaction conditions were studied (i.e., pH = 5.5, 0.1 mM QUIN, Triton X-114 = 0.1 % (w/v)), and the ...
Liu Chung-Pin - - 2013
Abstract The effect of angiotensin II (Ang II) on cytosolic Ca(2+) concentrations ([Ca(2+)]i) in MDCK renal tubular cells was explored. The Ca(2+)-sensitive fluorescent dye fura-2 was applied to measure [Ca(2+)]i. Ang II at concentrations of 5-40 µM induced a [Ca(2+)]i rise in a concentration-dependent manner. The response was reduced partly by ...
Davies Nicola - - 2013
You covered a colleague's shifts last weekend and worked your regular shifts this week and have not been at home for 36 consecutive hours for 12 days. As you update a patient's medication chart, you realise that you just recorded administering 10cc of morphine instead of 4cc. You have made ...
Fox Michael G - - 2013
We examined differences in pumpkinseed (Lepomis gibbosus) life-history traits between native North American and introduced European populations, and tested three life-history predictions related to the effect of temperature, growth, waterbody size, and the presence/absence of predators on native and non-native populations. Pumpkinseed populations exhibit more 'opportunistic' traits (earlier maturity, smaller ...
Nakanoko Tomonori - - 2013
Neoadjuvant chemoradiotherapy (NACRT) for esophageal squamous cell carcinoma (ESCC) is beneficial in the setting of a complete pathological response. Rad51 expression affects both chemo- and radiosensitivity in many cancers; however, its role in ESCC is unclear. Rad51 expression was investigated by immunohistochemical staining with resected specimens in 89 ESCC patients ...
Hsu Shao-Jung - - 2013
Abnormal angiogenesis in liver cirrhosis often leads to severe complications as variceal hemorrhage and encephalopathy. Furthermore, splanchnic angiogenesis elevates portal pressure, in which angiogenic factors play pivotal roles. Green tea polyphenol (GTP) extracted from Camellia sinensis has anti-angiogenic properties, but the relevant effects on the aforementioned parameters in cirrhosis have ...
Okamoto Takeshi - - 2013
Abstract We investigated whether near-ultraviolet light emitted from light-emitting diodes (LEDs) effects Helicobacter pylori viability and whether this new method can potentially apply to eradication therapy. Three H. pylori strains were used for near-ultraviolet (UV) LED irradiation experiments. Viability of isolates exposed to near-UV light was compared with controls by ...
Okholm Cecilie - - 2013
Abstract Objective. Nurse Administered Propofol Sedation (NAPS) contributes to a deeper sedation of the patients, making them unable to respond to pain and an increased incidence of perforations has been speculated. The objective of this study was to evaluate the risk of perforations during colonoscopies performed with either NAPS or ...
Zhang Ye - - 2013
Caveolin-1, a candidate tumor suppressor, interacts with a number of transducing molecules and plays a regulatory role in several signaling pathways. Recently, a study revealed that Cav-1 G14713A (rs3807987)/T29107A (rs7804372) polymorphisms might be associated with the susceptibility to certain cancers. In this study, we evaluated the interaction among Caveolin-1 genotypes ...
Fletcher Richard S - - 2013
The identification of the loci and specific alleles underlying variation in quantitative traits is an important goal for evolutionary biologists and breeders. Despite major advancements in genomics technology, moving from QTL to causal alleles remains a major challenge in genetics research. Near-isogenic lines are the ideal raw material for QTL ...
Lopes Marcos S - - 2013
Traditional breeding programs consider an average pairwise kinship between sibs. Based on pedigree information, the relationship matrix is used for genetic evaluations disregarding variation due to Mendelian sampling. Therefore, inbreeding and kinship coefficients are either over or underestimated resulting in reduction of accuracy of genetic evaluations and genetic progress. Single ...
Wang Kai-Ping - - 2013
In this study, five novel polysaccharides SLNT1, SLNT2, JLNT1, JLNT2 and JLNT3 were isolated from the fruit body of Lentinus edodes. Chemical and physical analyses showed that the five polysaccharides consist of glucose with the structure of β-(1→3)-D-glucose main chains and β-(1→6)-D-glucose side chains. Moreover, all of them had triple-helical ...
Evans Gaithiri - - 2013
I am trying to locate my old friend Janice M Arnold (née Brown). We completed our A-levels together at the Cambridge College of Arts and Technology in 1978.
Chowdhury Animesh - - 2013
We investigated the mechanism by which TxA2 mimetic, U46619, activates proMMP-2 in bovine pulmonary artery smooth muscle cells. Our study showed that treatment of the cells with U46619 caused an increase in the expression and subsequently activation of proMMP-2 in the cells. Pretreatment with p(38)MAPK inhibitor, SB203580; and NF-κB inhibitor, ...
Ellingson Jarrod M JM Department of Psychological Sciences, University of Missouri-Columbia, 210 McAlester Hall, Columbia, MO, 65211, USA, - - 2013
Numerous dual-systems models of personality have been posited, which propose that behavior is influenced by two complementary systems. A bottom-up system is characterized by emotion-based drive (e.g., urge for rewarding experience), and a top-down system is characterized by the ability to control those urges. Although evidence suggests that these two ...
da Silva L S M - - 2013
BACKGROUND/OBJECTIVES:The objectives of this study were to evaluate nutritional status, aptitude and physical activity at the beginning and end of the nutrition education and physical activity intervention program as compared with a control group.METHODS:We conducted a 28-week quasi-experimental study involving 238 students (108 in the intervention group (IG) and 130 ...
Zhang Yi-Hua - - 2013
New 1D lanthanide-organic frameworks, [Ln(dpdc)1.5(IP)(H2O)]n (Ln = Sm 1, Eu 2, Gd 3; dpdc = 2,2'-diphenyldicarboxylate and IP = 1H-imidazo[4,5-f][1,10]-phenanthroline), were synthesized. White light emission was realized by two approaches: a single component Sm(iii) framework and a two-component Eu(iii)-doped Gd(iii) framework.
Rhodes Lesley - - 2013
This review article outlines harmful algal bloom (HAB) monitoring practices in New Zealand and highlights the shift from light microscope (LM)-based identification and quantification of the early 1990s to the use of molecular tools to support the HAB monitoring programmes two decades later. Published research and available client information from ...
- - 2013
An interim suspension order was made against me at a Nursing and Midwifery Council (NMC) fitness to practise hearing recently and I was suspended from the register.
Ly Trang T TT Department of Endocrinology and Diabetes, Princess Margaret Hospital for Children, Perth, Western Australia, - - 2013
Hypoglycemia is a critical obstacle to the care of patients with type 1 diabetes. Sensor-augmented insulin pump with automated low-glucose insulin suspension has the potential to reduce the incidence of major hypoglycemic events. To determine the incidence of severe and moderate hypoglycemia with sensor-augmented pump with low-glucose suspension compared with ...
Carrillo J - - 2013
Dyskeratosis congenita (DC) is a rare inherited bone marrow failure syndrome with high clinical heterogeneity. Various mutations have been reported in DC patients, affecting genes that code for components of H/ACA ribonucleoproteins, proteins of the telomerase complex and components of the shelterin complex. We aim to clarify the role of ...
Wu Yong - - 2013
Aim: Oxidative stress induced by free fatty acids (FFA) contributes to metabolic syndrome-associated development of cardiovascular diseases yet molecular mechanisms remain poorly understood. This study aimed at establishing whether PTEN and its subcellular location play a role in FFA-induced endothelial oxidative stress. Results: Exposing human endothelial cells (ECs) with FFA ...
Ebert Jay R - - 2013
Unloading knee braces often are used after tibiofemoral articular cartilage repair. However, the experimental basis for their use in patients with normal tibiofemoral alignment such as those undergoing cartilage repair is lacking. The purpose of this study was to investigate the effect of varus and valgus adjustments to one commercially ...
Peña Isabel - - 2013
Crystalline samples of d-xylose have been vaporized by laser ablation and probed in the gas phase using Fourier transform microwave spectroscopy. The rotational spectrum revealed the existence of two α-d-xylopyranose conformers stabilized by the anomeric effect and cooperative hydrogen bond networks. The experiment spectroscopically tracked fine structural changes upon clockwise ...
Sancheti Jayant - - 2013
The present study was to investigate the anticonvulsant and antiepileptogenic potential of thymol. Anticonvulsant activity of thymol (5-100 mg/kg i.p.) was studied using maximal electroshock, pentylenetetrazole (PTZ), strychnine and 4-aminopyridine (4-AP) models. Thymol at the selected dose was also studied for its effect on locomotion. Antiepileptogenic property of thymol (5-25 mg/kg) was evaluated ...
Zou Y - - 2013
BACKGROUND/OBJECTIVES:This paper aims to compare children's thyroid volume (Tvol) by age and gender in Zhejiang province in order to explore the factors influencing Tvol in this area.SUBJECTS/METHODS:This survey was a cross-sectional survey of a provincial representative sample of Zhejiang province children aged 6-12 years. The children were asked to provide ...
Rodriguez-Rodriguez Patricia - - 2013
The rates of glucose oxidized at glycolysis and pentose-phosphate pathway (PPP) in neurons are controversial. Using [3-(3)H]-, [1-(14)C]-, and [6-(14)C]glucose to estimate fluxes through these pathways in resting, intact rat cortical primary neurons, we found that the rate of glucose oxidized through PPP was, apparently, ∼14% of total glucose metabolized. ...
Huang Wenhui - - 2013
Abstract Objective: To evaluate the efficacy and tolerability of lanthanum carbonate(LC) in the treatment of hyperphosphatemia in dialysis patients. Method: Multiple databases were used for recruit the published clinical randomized controlled trials(RCTs) comparing LC with placebo for hyperphosphatemia in dialysis patients from inception to March 2013. Results were expressed using ...
Van Maele L - - 2013
Antigen-presenting cell (APC) activation is enhanced by vaccine adjuvants. Most vaccines are based on the assumption that adjuvant activity of Toll-like receptor (TLR) agonists depends on direct, functional activation of APCs. Here, we sought to establish whether TLR stimulation in non-hematopoietic cells contributes to flagellin's mucosal adjuvant activity. Nasal administration ...
- - 2013
The Liberal Democrats are calling for staff who care for people in their own homes to receive training in equality and diversity, interpersonal skills and dealing with people with dementia.
Uddin Raza Mohy - - 2013
Prolactin (PRL) is a polypeptide hormone, secreted mainly by the anterior pituitary gland. It is involved in many endocrine activities. The key functions of PRL are related to reproduction and lactation in mammals. To ascertain the presence of polymorphisms in the bovine PRL gene (bPRL), the bPRL gene was sequenced. ...
Teeters Jenni B - - 2013
Compared to college females, college males are more likely to report frequent gambling. Research on gambling outcome expectancies has shown that expectations about gambling influence gambling behavior and that endorsement of particular expectancies differs by gender. Knowledge regarding the differential predictive utility of specific gambling expectancies based on gender would ...
Crommelin Daan J A DJ Department of Pharmaceutical Sciences, Utrecht University, P.O. Box 80.082, 3508 TB, Utrecht, The - - 2014
In the last decade, discussions on the development of the regulatory framework of generic versions of complex drugs such as biologicals and non-biological complex drugs have attracted broad attention. The terminology used is far from harmonized and can lead to multiple interpretations of legal texts, reflection papers, and guidance documents ...
Sampson J F - - 2013
Fragmentation is generally considered to have negative impacts on widespread outbreeders but impacts on gene flow and diversity in patchy, naturally rare, self-compatible plant species remain unclear. We investigated diversity, gene flow and contemporary pollen-mediated gene immigration in the rare, narrowly distributed endemic shrub Calothamnus quadrifidus ssp. teretifolius. This taxon ...
Ricci Maria Teresa - - 2013
The identification of women with a high probability of being carriers of pathogenic BRCA mutation is not straightforward and a major improvement would be the availability of markers of mutations that could be directly evaluated in individuals asking for genetic testing. The FMR1 gene testing was recently proposed as a ...
Kanbe Hiroki - - 2013
Epidemiological studies demonstrate a possible relationship between chronic ethanol drinking and thrombotic diseases, such as myocardial infarction and stroke. However, the precise mechanism for this association remains unclear. Sulfatides are endogenous glycosphingolipids composed of ceramide, galactose, and sulfate, known to have anti-thrombotic properties. Low (0.5 g/kg/day), middle (1.5 g/kg/day), and high (3.0 g/kg/day) ...
Lu Tong - - 2013
Abstract Objective: To develop an image visualization system based on graphic processing unit (GPU) hardware acceleration for clinical use in hepatocellular carcinoma (HCC) interventional planning. Methods: We developed a liver tumor planning tool to assist the physician in providing patient-specific analysis and visualization. We employed a spatial distance computation algorithm ...
Dehaes Mathieu M 1] Fetal Neonatal Neuroimaging and Developmental Science Center, Division of Newborn Medicine, Boston Children's Hospital, Boston, Massachusetts, USA [2] Department of Pediatrics, Harvard Medical School, Boston, Massachusetts, - - 2014
Pathophysiologic mechanisms involved in neonatal hypoxic ischemic encephalopathy (HIE) are associated with complex changes of blood flow and metabolism. Therapeutic hypothermia (TH) is effective in reducing the extent of brain injury, but it remains uncertain how TH affects cerebral blood flow (CBF) and metabolism. Ten neonates undergoing TH for HIE ...
Oxtoby Kathy - - 2013
Nursing students are expected to write essays of high quality. This task can be daunting, but there are some simple steps students can take to improve their work and boost their marks, writes Kathy Oxtoby.
Ma Yunyun - - 2013
Human T cell leukemia virus type 1 (HTLV-1) is an oncogenic retrovirus that can cause adult T-cell leukemia (ATL) and other diseases. The HTLV-1 bZIP factor (HBZ), which is encoded by an mRNA of the opposite polarity of the viral genomic RNA, interacts with several transcription factors and is involved ...
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