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Huang Wen - - 2013
Elevated thyrotropin (TSH) and hypercholesterolemia commonly coexist in patients with subclinical hypothyroidism, which can cause and aggravate heart disease. However, it is unclear whether TSH has a direct effect on cardiac function. To determine the expression of the thyrotropin receptor (TSHR) and the effects of TSH on ventricular function, we ...
Wu Xiaohong - - 2013
To investigate whether Nischarin participated in neuronal apoptosis induced by neuroinflammation and via the phosphatidylinositol 3-kinase (PI3K) and PKB-dependent pathway. Use of male Sprague-Dawley rats, rat pheochromocytoma (PC12), and murine microglial cells (BV-2). Treatment lipopolysaccharides (LPS) were injected into the brain lateral ventricle of the rat. The BV-2 cells were ...
Wang Quanfu - - 2013
Thioredoxin (Trx) is a highly conserved and multi-functional protein that plays a pivotal role in maintaining the redox state of the cell and in protecting the cell against oxidative stress. Trx gene from Antarctic sea-ice bacteria Pseudoalteromonas sp. AN178 was cloned and expressed as soluble protein in Escherichia coli (designated ...
Wang Shengman - - 2013
Heavy metal pollution and soil acidification are serious global environmental issues. The combined pollution from acidification and heavy metal has become a new environmental issue in regions where the two issues simultaneously occur. However, studies on combined pollution are still limited. In the current study, we investigated the combined effect ...
Markov Dmitry A - - 2013
Polydimethylsiloxane (PDMS) is a commonly used polymer in the fabrication of microfluidic devices due to such features as transparency, gas permeability, and ease of patterning with soft lithography. The surface characteristics of PDMS can also be easily changed with oxygen or low pressure air plasma converting it from a hydrophobic ...
Kim Jin Wook - - 2013
Despite the favorable outcomes of radiosurgery for central neurocytoma (CN), these results are based on case series that included a limited number of patients and short follow-up periods because of the scarcity of CN. Because CN is a benign tumor with an indolent clinical course, long-term follow-up and analysis of ...
Bode K - - 2013
In western countries one in ten of elderly persons (> 65 years old) will develop atrial fibrillation. The main goal in atrial fibrillation therapy is the prophylaxis of thromboembolic complications through anticoagulation according to the individual risk profile (CHA2DS2-Vasc score) of patients and treatment of cardiovascular comorbidities. Symptoms during atrial fibrillation ...
- - 2013
It is more than seven months since the government was asked to draw up a national uniform policy so that patients in English hospitals could distinguish easily between nurses and other staff. To date ministers have had nothing to say on the issue.
- - 2013
Essential facts About one in five patients who are emergency admissions to hospital will present with acute kidney injury (AKI), a condition that involves the loss of kidney function over hours or days. Despite its prevalence, there are low levels of awareness and education about AKI among healthcare professionals. Care ...
Savage Melanie - - 2013
Nurses are required to keep their knowledge and skills up to date to ensure their practice is evidence-based. Reflection in and on practice can be used to ensure care provision is evidence-based, to increase self-awareness and to promote positive change. Timely communication of high-quality information tailored to patients' needs is ...
Vaughan Julie - - 2013
Ambulatory emergency care units are present in many hospitals and accommodate patients who need urgent medical assessment or procedures but do not require inpatient admission to achieve this. This article reports on a project undertaken in the ambulatory care unit at the Royal United Hospital Bath, which introduced a nurse-led ...
Jones Ben - - 2013
Few jobs in nursing and health care are as stressful as those of nurse managers.
Colwell Ginny - - 2013
Increasing the probability of getting promoted usually starts long before the job advertisement appears.
Davies Nicola - - 2013
You covered a colleague's shifts last weekend and worked your regular shifts this week and have not been at home for 36 consecutive hours for 12 days. As you update a patient's medication chart, you realise that you just recorded administering 10cc of morphine instead of 4cc. You have made ...
Ballantyne Helen - - 2013
To be honest, my memories of the first few months of nurse training are rather hazy. As late-night partying is not my style, I attribute my amnesia to the kaleidoscope of emotions and events that I experienced.
Adams Michael - - 2013
At the beginning of your nursing career, remember that being a caring and compassionate nurse is an absolute priority. Studying for a degree does not change this - in fact, a better education should enhance these skills.
Day Karen - - 2013
Some students do not discover that they have dyslexia until they reach university and the realisation can be both a shock and a relief. Many develop good coping strategies and may not disclose their disability.
Bennetts Brett - - 2013
Uniquely, the ClC family harbours dissipative channels and anion/H(+) transporters that share unprecedented functional characteristics. ClC-1 channels are homodimers in which each monomer supports an identical pore carrying three anion-binding sites. Transient occupancy of the extracellular binding site by a conserved glutamate residue, E232, independently gates each pore. A common ...
Li Wei-Zhen - - 2013
The development of thermally stable, nanometer-sized precious metal-based catalysts remains a daunting challenge. Such materials, especially those based on the use of costly platinum metal, are essential and, to date, non-replaceable for a large number of industrially important catalytic processes. Here we report a well-defined cuboctahedral MgAl2O4 spinel support material ...
Rhodes Lesley - - 2013
This review article outlines harmful algal bloom (HAB) monitoring practices in New Zealand and highlights the shift from light microscope (LM)-based identification and quantification of the early 1990s to the use of molecular tools to support the HAB monitoring programmes two decades later. Published research and available client information from ...
Gillen Sally - - 2013
The RCN is calling for swift action to implement a recommendation on safe staffing by Robert Francis in his report on care failings at Mid Staffs.
Trueland Jennifer - - 2013
Nurses should be trained in recognising vision problems in patients following an acute stroke, according to guidance launched last week.
Keogh Kat - - 2013
Each year, front line NHS staff are offered a free seasonal flu vaccination to help protect them and their patients from picking up the virus.
Arif Zeba - - 2013
The health select committee has called on hospitals in England to display publicly the number of nurses on duty on each ward. The committee members say this would lead to greater openness and would help to increase trust in the NHS.
Stockwell Felicity - - 2013
I write in support of Benny Goodman's letter (September 18) questioning if revalidation can make any difference in improving nursing standards.
- - 2013
An interim suspension order was made against me at a Nursing and Midwifery Council (NMC) fitness to practise hearing recently and I was suspended from the register.
Bannister Richard - - 2013
Starting a three-year nursing programme is an exciting, yet daunting, time for most new students. This is especially true for mature students who may be entering higher education after many years away from any kind of study.
Carson Pauline - - 2013
Simulation learning is used in several health disciplines. The Department of Health defines simulation as 'any reproduction or approximation of a real event, process or set of conditions or problems'.
Ashby Sue - - 2013
Many people who have experienced health care are supporting nurse education programmes by informing students about their experiences and how their needs can be best met by healthcare professionals.
Humphries Belinda - - 2013
Practice experiences can be among the most memorable, enjoyable and rewarding times for students embarking on their nursing careers. They can also be thought-provoking, pressurised and challenging.
Neenan Trudi - - 2013
Part of my lecturer role involves helping students to gain confidence in numeracy.
Ly Trang T - - 2013
Hypoglycemia is a critical obstacle to the care of patients with type 1 diabetes. Sensor-augmented insulin pump with automated low-glucose insulin suspension has the potential to reduce the incidence of major hypoglycemic events. To determine the incidence of severe and moderate hypoglycemia with sensor-augmented pump with low-glucose suspension compared with ...
Hsu Po-Chun - - 2013
For transparent conducting electrodes in optoelectronic devices, electrical sheet resistance and optical transmittance are two of the main criteria. Recently, metal nanowires have been demonstrated to be a promising type of transparent conducting electrode because of low sheet resistance and high transmittance. Here we incorporate a mesoscale metal wire (1-5 μm ...
Brunner Stefan - - 2013
Endogenous circulation of bone marrow-derived cells (BMCs) was observed in patients with dilated cardiomyopathy (DCM) who showed cardiac upregulation of Vascular Cell Adhesion Protein-1 (VCAM-1). However, the underlying pathophysiology is currently unknown. Thus, we aimed to analyze circulation, migration and G-CSF-based mobilization of BMCs in a murine model of virus-induced ...
Travis Mike - - 2013
Peter Cheese, chief executive of the Chartered Institute of Personnel and Development, says that zero-hours contracts, when used appropriately, can provide flexibility for employers and employees alike (Letters September 18). But he sits on the fence with regard to zero-hours contracts in the NHS and fails to address any criticism ...
Bethel James - - 2013
The assessment of suicidal intent in first-contact settings, including the emergency department, can be challenging. Inaccurate assessment can lead to increased incidence of self-harm and completion of suicide. This article focuses on factors that may affect review of this patient group, including healthcare professionals' personal and professional standards and values. ...
Morrow Abby - - 2013
Mental and physical health are intrinsically linked to a person's ability to maintain good physical health determined, in part, by his or her mental wellbeing. Similarly, poor physical health can lead to mental health problems.
Singh Shalini - - 2013
Homogenously alloyed CdSexS1-x nanorods with controlled aspect ratios are synthesised by a hot-injection colloidal route. The optical absorption and photoluminescence emission are compositionally tunable with chalcogen ratios. The synthetic protocol is sufficiently robust to allow good control of rod aspect ratios, with low polydispersities, suited for their rational assembly into ...
Zhao Ying - - 2013
Assembly of 5-nitro-1,2,3-benzenetricarboxylic acid (H3nbta) with Cu(II) in the presence of 1,3-bis(1,2,4-triazol-1-yl)propane (1,3-btp) leads to a new metal-organic framework, [Cu(Hnbta)(1,3-btp)]·2H2O (), which is shown to be an efficient and recyclable heterogeneous catalyst for enamination of β-ketoesters with excellent product yields and selectivity.
Ko Hae Young - - 2013
NIRF imaging of carbon nanodots derived from tire soot was clearly visualized in glioma in vitro and in vivo.
Sun Hua - - 2013
A silicon nanoparticle solution (size ≅ 50 nm) with the concentration of 100 mM, which is contamination free, was synthesized using a ball milling method and was stable for 4 months without aggregation. This stability was responsible for large negative zeta potential on the surface of Si-NPs, established by milling ...
Denaro Nerina - - 2013
Treatment of unresectable, locally advanced head and neck cancer consists of many different options, all of them based on radiotherapy. The main variable is represented by chemotherapy, i.e., the way in which chemotherapy is combined with radiation. More recently, the combination of cetuximab and radiotherapy emerged as a new treatment ...
Parsons Sheena M A - - 2013
Animal body size often varies systematically along latitudinal gradients, where individuals are either larger or smaller with varying season length. This study examines ecotypic responses by the generalist grasshopper Melanoplus femurrubrum (Orthoptera: Acrididae) in body size and covarying, physiologically based life history traits along a latitudinal gradient with respect to ...
Melero Yolanda - - 2013
Trophic relationships between invasive species in multiply invaded ecosystems may reduce food limitation relative to more pristine ecosystems and increase resilience to control. Here, we consider whether invasive predatory American mink Neovison vison are trophically subsidized by invasive crayfish. We collated data from the literature on density and home range ...
Cocco Emiliano - - 2013
Doxorubicin (DOX) is an anticancer drug with cardiotoxic side effects mostly caused by iron homeostasis dysregulation. Mitochondria are involved in iron trafficking and mitochondrial ferritin (FtMt) was shown to provide protection against cellular iron imbalance. Therefore, we hypothesized that FtMt overexpression could limit DOX effects on iron homeostasis. Heart's homogenates ...
Liao Weiyong - - 2013
Cross-sectional studies have demonstrated a reverse relationship between serum level of testosterone (T) and the incidence rate of cardiovascular disease in men, indicating that T exerts beneficial effects in cardiovascular system. However, the endothelial effects of T are poorly understood. Actin remodeling is essential for endothelial cell movement and vascular ...
Rudnicka Helena - - 2013
BRCA1 and BRCA2 are two major genes associated with familial breast and ovarian cancer susceptibility. In Poland standard BRCA gene test is usually limited to Polish founder BRCA1 mutations: 5382insC, C61G and 4153delA. To date, just a few single large genomic rearrangements (LGRs) of BRCA1 gene have been reported in ...
Sun Rongbin - - 2013
Rheumatoid arthritis (RA) and ankylosing spondylitis (AS) are autoimmune, inflammatory diseases with substantial genetic contributions. Matrix metalloproteinase (MMP)-2, tumor necrosis factor (TNF)-α and NLR family pyrin domain-containing 1 (NLRP1) play important roles in the immune response. We studied the MMP-2 rs243865 C/T, TNF-α rs1800629 A/G, NLRP1 rs878329 C/G and NLRP1 ...
Zhang Hong - - 2013
The non-protein-coding genes have been reported as a critical control role in the regulation of gene expression in abiotic stress. We previously identified four expressed sequence tags numbered S18 (EL773024), S73 (EL773035), S106 (EL773041) and S108 (EL773042) from a SSH-cDNA library of bread wheat Shaanmai 139 infected with Puccinia striiformis ...
Wu Ying - - 2013
The serotonin 2A (5-HT2A) receptor has been implicated in obstructive sleep apnea (OSA). Single nucleotide polymorphisms (SNPs) in the 5-HT2A gene have been found in OSA, the most common being -1438G/A and T102C; however, studies of the association between 5-HT2A SNPs and OSA risk have reported inconsistent findings. A meta-analysis ...
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