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Stall Alec A From the R Adams Cowley Shock Trauma Center, Department of Orthopaedics, University of Maryland School of Medicine, Baltimore, - - 2013
Higher concentrations of fraction of inspired oxygen (FIO2) have been shown to be associated with lower risk for surgical site infection in multiple studies outside the domain of orthopedic surgery. We evaluated the efficacy of high FIO2 administered during the perioperative period to reduce the rate of surgical site infection ...
Yanchar Natalie L - - 2013
With the increasing use of thoracic computed tomography (CT) to screen for injuries in pediatric blunt thoracic trauma (BTT), we determined whether chest x-ray (CXR) and other clinical and epidemiologic variables could be used to predict significant thoracic injuries, to inform the selective use of CT in pediatric BTT. We ...
Therese K L - - 2013
Background: Early diagnosis of tuberculosis is critical for its effective management and prevention. Several gene amplification methods are used in the detection of tubercle bacilli from clinical specimens. MPB64 gene and IS6110 region have been identified as potential gene targets for the specific detection of Mycobacterium tuberculosis from direct clinical ...
McClung Christopher D CD From the Ohio State Medical Center (C.D.M.), Columbus, Ohio; Department of Urology (J.M.H., H.W., B.B.V.), University of Washington Medical Center; and Harborview Injury Prevention and Research Center (J.W., H.W., B.B.V.), Seattle, - - 2013
The National Trauma Data Bank was used to analyze open surgical management of renal trauma during the first 24 hours of hospital admission, excluding those who were treated with conservative measures. A descriptive analysis of initial management trends following renal trauma was also performed as a secondary analysis. With the ...
Zhu Jing - - 2013
The purpose of this work was to preliminarily investigate the efficacy and safety of high-intensity focused ultrasound treatment of hepatocellular carcinoma and hypersplenism. Nine patients with hepatocellular carcinoma complicated by hypersplenism (5 male and 4 female; median age, 56 years; range, 51-66 years) were treated with ultrasound-guided high-intensity focused ultrasound. ...
Levinger Eliya - - 2013
To describe our experience with monovision excimer laser correction in individuals with myopic presbyopia. This prospective interventional case series was conducted in a private refractive surgery center on 40 patients with presbyopia aged 40 years and older, who were treated with monovision refractive surgery between 2010 and 2011. The dominant ...
Taylor Jeremy - - 2013
THERE IS much talk in health and care about 'putting patients first', but the words staff and managers use often tell a different story. Health care is replete with platitude, jargon and euphemism, perhaps more than other fields of endeavour. Worst of all are terms that denigrate or alienate patients.
Triggle Nick - - 2013
NURSES ARE to be handed a crucial role in ensuring that care providers are up to standard, with the introduction of a new hospital inspection regime in England.
Sherman Murray H - - 2013
The author explores the relationships of three major figures: Theodor Reik, Arthur Schnitzler, and Sigmund Freud. He considers how Schnitzler's novella "The Murderer" impacted Reik's life in terms of both Freud's reference to the story in a session with Reik and the parallels between Reik's life and the plot of ...
Payne Zachary M ZM Environet, Inc., 1286 Queen Emma Street, Honolulu, Hawaii 96813, USA. - - 2013
A nine-month in situ bioremediation study was conducted in Makua Military Reservation (MMR) in Oahu, Hawaii (USA) to evaluate the potential of molasses to enhance biodegradation of royal demolition explosive (RDX) and high-melting explosive (HMX) contaminated soil below the root zone. MMR has been in operation since the 1940's resulting ...
Calanna Salvatore S Corresponding author: Filip K. Knop, - - 2013
To investigate glucose-dependent insulinotropic polypeptide (GIP) secretion in patients with type 2 diabetes and nondiabetic control subjects during oral glucose or meal tests. Eligible trials were identified by The Cochrane Library, MEDLINE, Embase, and Web of Science. Data were retrieved and random-effects models for the primary meta-analysis, random-effects meta-regression, and ...
Leeson David - - 2013
This article discusses a short leadership programme for nurse and allied health professional leaders working in a community or community hospital environment in England. It describes the adoption, adaption, implementation, delivery and interim evaluation of the programme. The article sets out the background that led to adoption of the 7 ...
Ley Eric J - - 2013
Gender may influence outcomes following traumatic brain injury (TBI) although the mechanism is unknown. Animal TBI studies suggest that gender differences in endogenous hormone production may be the source. Limited retrospective clinical studies on gender present varied conclusions. Pediatric patients represent a unique population as pubescent children experience up-regulation of ...
Vaishnavi C - - 2013
Bacterial translocation is the invasion of indigenous intestinal bacteria through the gut mucosa to normally sterile tissues and the internal organs. Sometimes instead of bacteria, inflammatory compounds are responsible for clinical symptoms as in systemic inflammatory response syndrome (SIRS). The difference between sepsis and SIRS is that pathogenic bacteria are ...
Yang Seung Nam - - 2013
Objectives- The aim of this study was to measure the degree of movement of the ulnar nerve in the cubital tunnel using sonography in patients with ulnar neuropathy at the elbow compared to a healthy control group. Methods- We examined the ulnar nerve in the cubital tunnel using sonography with ...
Ryan Patrick H PH Cincinnati Children's Hospital Medical Center, Division of Biostatistics and Epidemiology, Cincinnati Children's Hospital Medical Center, 3333 Burnet Ave, ML 5041, Cincinnati, OH 45229, USA. - - 2013
Idling school buses may increase concentrations of air pollutants including fine particulate matter (PM2.5) and elemental carbon (EC) near schools. Efforts to reduce vehicle idling near schools have rarely included air sampling to objectively assess changes in concentrations of air pollutants. The objective was to determine the impact of an ...
Looper Jessica K JK Department of Civil Engineering, Auburn University, Auburn, AL 36849, USA. - - 2013
We investigated the impact of the Deepwater Horizon oil spill on microbial communities in wetland sediment and seawater samples collected from sites along the Gulf shore. Based on GC/MS analysis, the sediment from Bay Jimmy, LA had detectable signs of hydrocarbon contamination, identified as n-alkanes in the GC/MS spectrum similar ...
Froehner Sandro S Department of Environmental Engineering, Federal University of Parana, CEP 81531-990, Curitiba, Parana, Brazil. - - 2013
The use of biofilms for adsorption of sterols was investigated for the first time to evaluate sewage contamination in the Barigüi River, Curitiba (Brazil). The characteristics of a biofilm that favor its use in monitoring include the relatively rapid development of biofilms and their capacity to sorb hydrophobic compounds. Some ...
Barnard Katharine K Corresponding author: Katharine Barnard, - - 2013
Antidepressant use has risen sharply over recent years. Recent concerns that antidepressants may adversely affect glucose metabolism require investigation. Our aim was to assess the risk of type 2 diabetes associated with antidepressants through a systematic review. Data sources were MEDLINE, Embase, PsycINFO, The Cochrane Library, Web of Science, meeting ...
Watts Jenny - - 2013
A survey of nurses working with older adults across three NHS trusts was conducted to explore how perceptions of the workplace affect nurse wellbeing. Standardised validated measures were used to assess burnout, perceived organisational support and organisational culture. Significant associations were found between innovative organisational culture and nurses' sense of ...
Mekjarasnapha Manasicha - - 2013
Objectives- The purpose of this study was to establish reference ranges for septum primum excursion and the septum primum excursion index. Methods- Normal singleton pregnancies with certain dates from 14 to 40 weeks' gestation were enrolled to acquire spatiotemporal image correlation volume data sets. The stored data sets were subsequently ...
Wright Greg - - 2013
Patient satisfaction is an important outcome measurement in the emergency department (ED). When unavoidable, the negative effect of patient wait time may be lessened by communicating expected wait time, affective support, health information, decisional control, and competent providers. This controlled quasi-experimental design used a convenience sample. The patient questionnaire included ...
Aziz Hassan - - 2013
Opinion is divided on the role of routine repeat head computed tomography (RHCT) for guiding clinical management in pediatric patients with blunt head trauma. We hypothesize that routine RHCT does not lead to change in management in mild and moderate traumatic brain injury (TBI). This is a 3-year retrospective study ...
Deretic Vojo V Department of Molecular Genetics and Microbiology, University of New Mexico Health Sciences Center, 915 Camino de Salud, North East, Albuquerque, New Mexico 87131, - - 2013
Autophagy is a fundamental eukaryotic pathway that has multiple effects on immunity. Autophagy is induced by pattern recognition receptors and, through autophagic adaptors, it provides a mechanism for the elimination of intracellular microorganisms. Autophagy controls inflammation through regulatory interactions with innate immune signalling pathways, by removing endogenous inflammasome agonists and ...
Blakeman Thomas C - - 2013
Oxygen in arguably one of the most frequently utilized drugs in modern healthcare, but is often administered to patients at caregivers' discretion with scant evidence as to its efficacy or safety. Although oxygen is administered for varied medical conditions in the hospital setting, published literature supports the use of oxygen ...
Jacobsen Henrik Borsting HB From the Harvard School of Public Health (Drs Jacobsen, Caban-Martinez, Sorensen, Dennerlein, and Reme and Ms Onyebeke), Northeastern University (Dr Dennerlein), and Dana-Farber Cancer Institute (Dr Sorensen), Boston, Mass; Uni Health (Dr Reme), Uni Research, Bergen, Norway; and Norwegian University of Science and Technology (Dr Jacobsen), Trondheim, - - 2013
We aimed to investigate how mental distress was associated with pain and injuries in a convenience sample of construction workers. A cross-sectional, mental health assessment was conducted in a convenience sample of construction workers (N = 172). A subsample participated in a clinical interview (n = 10). We used a ...
Rodriguez-Merchan E Carlos - - 2013
Acute compartment syndrome (ACS) is characterized by an increase in pressure (intramuscular pressure) within a muscle compartment, which reduces capillary perfusion threatening tissue survival. Persistence of this increased pressure for a few hours will result in necrosis of muscle and nerve tissue, with contracture in the affected limb and permanent ...
Park Joong Hyun - - 2013
Objectives- We measured the carotid intima-media thickness, a surrogate marker of early atherosclerosis, in patients with carpal tunnel syndrome compared to a control group to evaluate the risk of atherosclerotic disease. Methods- Between January 2011 and December 2011, female patients presenting to the outpatient neurology clinic for pain and paresthesia ...
Lipley Nick - - 2013
NHS LEADERS are warning that emergency services could experience a meltdown this winter unless the country faces up to the true reasons they are under pressure.
Mejaddam Ali Y - - 2013
Heart rate complexity (HRC), commonly described as a "new vital sign," has shown promise in predicting injury severity, but its use in clinical practice has been precluded by the absence of real-time data. This study was conducted to evaluate the utility of real-time, automated, instantaneous, hand-held heart rate entropy analysis ...
Bornstein Eran - - 2013
We report 2 cases in which first-trimester measurements of the intracranial translucency and the brain stem-to-occipital bone diameter were markedly enlarged. This finding was thought to represent an abnormal fourth ventricle-cisterna magna complex. Subsequently, the diagnoses of a Dandy-Walker malformation with partial vermian agenesis in 1 case and inferior vermian ...
Shah Avni - - 2013
To describe a case of bilateral optic nerve head drusen (ONHD) in a pediatric patient and the complementary use of advanced noninvasive imaging techniques to confirm this diagnosis. A 15-year-old female adolescent with type 1 diabetes and no ocular history was seen at a routine screening without complaints. Visual acuity ...
Chan John K C - - 2013
With advances in immunohistochemical technology and growing knowledge of the molecular genetics of tumors, immunohistochemistry is playing an increasingly important role in providing genetic information for tumors. Specific chromosomal translocations can be demonstrated through detection of the protein product of one of the genes involved in gene fusion (such as ...
Depestel Daryl D DD Medical Affairs, Cubist Pharmaceuticals Inc, Lexington, MA, - - 2013
There has been dramatic change in the epidemiology of Clostridium difficile infection (CDI) since the turn of the 21st century noted by a marked increase in incidence and severity, occurring at a disproportionately higher frequency in older patients. Historically considered a nosocomial infection associated with antibiotic exposure, CDI has now ...
Wu Size - - 2013
Objectives- The purpose of this study was to investigate the stability of focal fatty sparing of the liver and its clinical implications. Methods- This prospective study consisted of 2 parts. In the first part, patients who underwent sonography and computed tomography (CT) or magnetic resonance imaging (MRI) were selected, and ...
Mitchell Marion - - 2013
Recruitment processes need to discriminate among candidates to ensure that the right person with the right skills is selected for advancement opportunities. An innovative recruitment process using an objective structured clinical examination grounded in best practice guidelines resulted in improved recruitment practices for senior nursing clinical expert roles. Candidates' skills, ...
Abellán E - - 2013
To design and validate a simulator for learning and training in the capsulorhexis technique. The system consists of a methacrylate support inclined 15° for the surgeon's hand, an area of commercially available aluminum foil, and another one of similar characteristics, where the student performs the technique through some slots that ...
Karlsson Fredrik F Department of Chemical and Biological Engineering, Chalmers University of Technology, Gothenburg, - - 2013
Recent findings have demonstrated that the gut microbiome complements our human genome with at least 100-fold more genes. In contrast to our Homo sapiens-derived genes, the microbiome is much more plastic, and its composition changes with age and diet, among other factors. An altered gut microbiota has been associated with ...
Duggal S - - 2013
Ralstonia paucula (formerly classified as CDC (Centre for Disease Control) group IVc-2, Wautersia paucula; recently renamed as Cupriavidus pauculus) is an environmental Gram-negative bacillus isolated from water sources and can cause serious human infections. Patients recover bacteriologically indicating low virulence. A total of 32 cases have been reported world-wide, but ...
Polanco Patricio M - - 2013
Despite a shift toward nonoperative management (NOM) of blunt liver trauma, severe injuries continue to require operative management. Our objective was to examine current trends of NOM for severe blunt liver injury from a national perspective. Patients with blunt liver injury with Abbreviated Injury Scale (AIS) score of 4 or ...
Walter Uwe - - 2013
The detection of an enlarged echogenic size ("hyperechogenicity") of the substantia nigra on transcranial sonography is increasingly used for the early and differential diagnosis of Parkinson disease. However, the diagnostic value of substantia nigra sonography depends on the quality of its execution. This article with an accompanying video presents a ...
- - 2013
NHS England is seeking views to help shape the future of primary care services in England through its Improving General Practice: A Call to Action survey.
Mina Michael Joseph - - 2013
The use of massive transfusion protocols (MTPs) is now common in civilian trauma settings, and early activation of MTP has been shown to increase survival of MTP recipients. Numerous MTP prediction tools have been developed; however, they are often cumbersome to use efficiently or have traded predictive power for ease ...
Lawnick Mary M - - 2013
The current civilian Abbreviated Injury Scale (AIS), designed for automobile crash injuries, yields important information about civilian injuries. It has been recognized for some time, however, that both the AIS and AIS-based scores such as the Injury Severity Score (ISS) are inadequate for describing penetrating injuries, especially those sustained in ...
Brancolini Giorgia G CNR Institute of Nanoscience , S3 Center, Via Campi 213/A, 41125 Modena, - - 2013
We address the issue of whether chemical alterations of nucleobases are an effective tool to modulate charge transfer through DNA molecules. Our investigation uses a multilevel computational approach based on classical molecular dynamics and quantum chemistry. We find yet another piece of evidence that structural fluctuations are a key factor ...
Wu Xiaohong - - 2013
To investigate whether Nischarin participated in neuronal apoptosis induced by neuroinflammation and via the phosphatidylinositol 3-kinase (PI3K) and PKB-dependent pathway. Use of male Sprague-Dawley rats, rat pheochromocytoma (PC12), and murine microglial cells (BV-2). Treatment lipopolysaccharides (LPS) were injected into the brain lateral ventricle of the rat. The BV-2 cells were ...
Zhang Long Jiang - - 2013
To investigate the pattern of brain volume changes in patients with end-stage renal disease (ESRD) using voxel-based morphometry (VBM) and correlation with clinical and neuropsychological (NP) tests. Fifty seven ESRD patients with no anatomical abnormalities in conventional magnetic resonance imaging [24 patients with abnormal NP scores, 16 male, 39 ± 12 years; 33 ...
Kim Jin Wook - - 2013
Despite the favorable outcomes of radiosurgery for central neurocytoma (CN), these results are based on case series that included a limited number of patients and short follow-up periods because of the scarcity of CN. Because CN is a benign tumor with an indolent clinical course, long-term follow-up and analysis of ...
Bode K - - 2013
In western countries one in ten of elderly persons (> 65 years old) will develop atrial fibrillation. The main goal in atrial fibrillation therapy is the prophylaxis of thromboembolic complications through anticoagulation according to the individual risk profile (CHA2DS2-Vasc score) of patients and treatment of cardiovascular comorbidities. Symptoms during atrial fibrillation ...
Wang Quanfu - - 2013
Thioredoxin (Trx) is a highly conserved and multi-functional protein that plays a pivotal role in maintaining the redox state of the cell and in protecting the cell against oxidative stress. Trx gene from Antarctic sea-ice bacteria Pseudoalteromonas sp. AN178 was cloned and expressed as soluble protein in Escherichia coli (designated ...
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