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Results 451 - 500 of 4535
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Stockwell Felicity - - 2013
I write in support of Benny Goodman's letter (September 18) questioning if revalidation can make any difference in improving nursing standards.
Wang Honglian - - 2013
Adaptor protein complex 4 (AP-4) plays a key role in vesicle formation, trafficking, and sorting processes that are critical for brain development and function. AP-4 consists of four subunits encoded by the AP4E1, AP4B1, AP4M1, and AP4S1 genes. A number of studies have pointed to the involvement of AP-4-mediated vesicular ...
Dommanget Fanny - - 2013
Asian knotweeds (Fallopia spp.) are considered one of the world's most invasive species. Restoring habitats dominated by these exotic species requires a better understanding of the importance of abiotic factors controlling the invasive knotweeds performance. We used observational data obtained on the embankment of the Isère River (France) to study ...
Sears Jeanne M - - 2013
Purpose Workers' compensation-based vocational rehabilitation (VR) programs are costly and challenging to operate effectively. This study aimed to: (1) describe injured workers' assessment of Washington State's VR system before and after vocational retraining, (2) describe the factors affecting injured worker satisfaction with VR services, and (3) gather suggestions for program ...
Frias Vilaça Ana A Department of Imagiology, Hospital-Escola da Universidade Fernando Pessoa, Gondomar, Porto, Portugal, - - 2013
Air/gas outside the aero-digestive tract is abnormal; depending on its location, it is usually called emphysema, referring to trapped air/gas in tissues, or ectopic air/gas. It can be associated to a wide range of disorders, and although it usually is an innocuous condition, it should prompt a search for the ...
Belluti Federica - - 2013
Malaria, a disease of worldwide significance, is responsible for over one million deaths annually. The liver-stage of Plasmodium's life cycle is the first, obligatory, but clinically silent step in malaria infection. The P. falciparum type II fatty acid biosynthesis pathway (PfFAS-II) has been found to be essential for complete liver-stage ...
Kuila Biplab K - - 2013
Here, we describe a novel and versatile approach for fabrication of multilayer polymeric thin films with a tunable, ordered periodic structure in each layer using self-assembly of block copolymers. Different functional nanomaterials are selectively introduced in different layers with controlled arrays and network formation resulting in ordered multifunctional nanocomposite thin ...
Aswad Muhammad - - 2013
We report a coupling reaction of thioamides and sulfonyl azides to generate sulfonyl amidines in the absence of any activation additives. The reaction progresses in various solvents under mild conditions. Water exhibits the highest performance with respect to efficiency.
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Large labour wards handling 3,000 to 3,999 deliveries annually have lower rates of successful obstetric injury claims from patients compared to smaller or very large obstetric units, reveals a study from Denmark.
Bannister Richard - - 2013
Starting a three-year nursing programme is an exciting, yet daunting, time for most new students. This is especially true for mature students who may be entering higher education after many years away from any kind of study.
Sun Xiujuan - - 2013
Fluorine-doped carbon blacks as inexpensive, high performance electrocatalysts for acidic oxygen reduction reaction were synthesized. The performance of the optimal catalyst (BP-18F) is close to the level of other reported best non-Pt electrocatalysts in acid, but with superlow H2O2 yield (<0.1%) ever. Their high performance is confirmed by quantum calculations.
W─ůsik Agnieszka - - 2013
Oxidative stress is a major contributing factor in a range of brain pathologies and in the etiology of depression. 1-Methyl-1,2,3,4-tetrahydroisoquinoline (1MeTIQ) is an endogenous substance which is present in the mammalian brain and exhibits neuroprotective, and monoamine oxidase (MAO)-inhibiting properties. In the present study, in order to investigate the potential ...
Meng Huaxing - - 2013
ABSTRACT rhEPO has previously been shown to exert neuroprotective action in focal cerebral ischemia. However, its mechanism is not clear. We established the model of permanent focal cerebral ischemia. rhEPO was administered (5000 IU/kg i.p.) 2h later after the successful ischemia model in rhEPO group, rhEPO increased translation of Nrf2, ...
Solanas Guiomar - - 2013
In the past years, our view of the molecular and cellular mechanisms that ensure the self-renewal of the skin has dramatically changed. Several populations of stem cells have been identified that differ in their spatio-temporal contribution to their compartment in steady-state and damaged conditions, suggesting that epidermal stem cell heterogeneity ...
Alipour Hossein - - 2013
The concentrations of four heavy metals (Pb, Cd, Ni and Cr) were measured in tissues of pelagic (Rutilus caspicus) and benthic (Neogobius gorlap) fishes from the Miankaleh international wetland. The maximum concentrations of Pb, Cd, Ni, and Cr (2.06, 1.20, 1.14 and 0.70 μg g(-1), respectively) were measured in the liver of ...
Oh Kyung-Hwan - - 2013
In order to investigate the interaction of well-known regulation systems, quorum sensing and stringent response for the expression of virulence genes in enterohemorrhagic Escherichia coli (EHEC), E. coli strains with mutations in the two regulation systems, ΔluxS (ECM101) and ΔluxSΔrelAΔspoT (ECM201), and ΔluxS complemented strain to ECM201 (ECM202) were created ...
- - 2013
An NHS trust is screening a series of sequels to an award-winning film about a patient with dementia that has been watched worldwide.
Polakova Vymetalkova Veronika - - 2013
Altered expression and methylation pattern of tumor suppressor and DNA repair genes, in particular involved in mismatch repair (MMR) pathway, frequently occur in primary colorectal (CRC) tumors. However, little is known about (epi)genetic changes of these genes in precancerous and early stages of CRC. The aim of this pilot study ...
Zou Peng - - 2013
Rapid premature release of lipophilic drugs from liposomal lipid bilayer to plasma proteins and biological membranes is a challenge for targeted drug delivery. The purpose of this study is to reduce premature release of lipophilic short-chain ceramides by encapsulating ceramides into liposomal aqueous interior with the aid of poly (lactic-coglycolicacid) ...
Gupta Bhanushree - - 2013
Oxime-assisted reactivation of organophosphate (OP)-inhibited acetylcholinesterase (AChE) is a crucial step in the post-inhibitory treatment of OP intoxication. The limited efficacy of oxime reactivators for all OP nerve agents and pesticides led to the development of various novel oximes and their thorough kinetic investigations. Hence, in the present investigation, we ...
Sudan Madhuri - - 2013
In this study, we demonstrate the complexities of performing a sibling analysis with a re-examination of associations between cell phone exposures and behavioral problems observed previously in the Danish National Birth Cohort. Children (52,680; including 5441 siblings) followed up to age 7 were included. We examined differences in exposures and ...
Banerjee Arnab - - 2013
A pyrene-thiophene conjugate has been used for the efficient detection of intracellular irons through the generation of bright green luminescence. Amongst three different probes being reported, it is observed that the efficiency for the naked eye green luminescent detection of iron increases on moving from naphthalene to anthracene to pyrene. ...
Flombaum Pedro - - 2013
Resource partitioning, facilitation, and sampling effect are the three mechanisms behind the biodiversity effect, which is depicted usually as the effect of plant-species richness on aboveground net primary production. These mechanisms operate simultaneously but their relative importance and interactions are difficult to unravel experimentally. Thus, niche differentiation and facilitation have ...
Sibin M K - - 2013
Over the years, deletions of CDKN2A (p16) tumor suppressor gene has been studied using FISH and multiplex PCR, with major focus on exon 2 in various cancers, and the frequency of mutation is found to be varied in different studies. In this study, we analyzed the deletion status of all ...
Samanta Subhas - - 2013
Introduction of S-ethyl groups in all four ortho positions of azobenzene prevents reduction of the azo group by intracellular glutathione, while enhancing the absorptivity to ∼10 000 M(-1) cm(-1) in the blue and green regions of the visible spectrum. cis-to-trans isomerization occurs thermally on the minutes timescale. Further, this substitution pattern ...
Ashby Sue - - 2013
Many people who have experienced health care are supporting nurse education programmes by informing students about their experiences and how their needs can be best met by healthcare professionals.
Ko Hae Young - - 2013
NIRF imaging of carbon nanodots derived from tire soot was clearly visualized in glioma in vitro and in vivo.
Dodson Rebecca M - - 2013
Assessment of patient performance status is often subjective. Sarcopenia-measurement of muscle wasting-may be a more objective means to assess performance status and therefore mortality risk following intra-arterial therapy (IAT). Total psoas area (TPA) was measured on cross-sectional imaging in 216 patients undergoing IAT of hepatic malignancies between 2002 and 2012. ...
Van Diest Mike - - 2013
Fall injuries are responsible for physical dysfunction, significant disability, and loss of independence among elderly. Poor postural control is one of the major risk factors for falling but can be trained in fall prevention programs. These however suffer from low therapy adherence, particularly if prevention is the goal. To provide ...
Duval K - - 2013
BACKGROUND/OBJECTIVE:The purpose of this study was to investigate changes in dietary intake and appetite across the menopausal transition.SUBJECTS/METHODS:This was a 5-year observational, longitudinal study on the menopausal transition. The study included 94 premenopausal women at baseline (age: 49.9±1.9 years; BMI: 23.3±2.3 kg/m(2)). Body composition (dual-energy X-ray absorptiometry), appetite (visual analogue scale), ...
Giulitti Stefano - - 2013
Long-term cell culture in microfluidic devices is an essential prerequisite for "on a chip" biological and physiological based studies. We investigated how medium delivery, from continuous to periodic perfusion, affects long-term cell cultures in a microfluidic platform. Computational simulations suggested that different delivery strategies result in different temporal profiles of ...
Morrow Abby - - 2013
Mental and physical health are intrinsically linked to a person's ability to maintain good physical health determined, in part, by his or her mental wellbeing. Similarly, poor physical health can lead to mental health problems.
Zheng Tao - - 2013
The first examples of metal phosphonates based on 4-(ethoxycarbonyl)naphthanen-1-yl)phosphonic acid (4-cnppH2) are reported, namely, Co(4-cnpp) (), Co2(4-cnpp)2(dptz) () and Co2(4-cnpp)2(4,4'-bpy)(H2O) () (dptz = 3,6-di(pyridin-3-yl)-1,2,4,5-tetrazine, 4,4'-bpy = 4,4'-bipyridine). The cobalt atoms are four-coordinated with distorted tetrahedral geometries in both and , while five-coordinated with a distorted trigonal bipyramidal environment in compound ...
Seidensticker M - - 2013
This study was conducted to investigate the capacity of (99m)Tc-labeled 1-thio-β-D-glucose ((99m)Tc-1-TG) and 5-thio-D-glucose ((99m)Tc-5-TG) to act as a marker for glucose metabolism in tumor cells in vitro. We investigated the cellular uptake of (99m)Tc-1-TG, (99m)Tc-5-TG, and 2-deoxy-2-[(18) F]fluoro-D-glucose((18) F-FDG) in a human colorectal carcinoma and human lung adenocarcinoma cell line (HCT-116, ...
Li Jiang - - 2013
An extracellular agarase was purified from Bacillus sp. BI-3, a thermophilic agar-degrading bacterium isolated from a hot spring in Indonesia. The purified agarase revealed a single band on sodium dodecyl sulfate-polyacrylamide gel electrophoresis, with an apparent molecular weight of 58 kDa. The optimum pH and temperature of the agarase were ...
Turner D L - - 2013
The extent to which tissue-specific viral infections generate memory T cells specifically adapted to and maintained within the target infection site is unknown. Here, we show that respiratory virus-specific memory T cells in mice and humans are generated and maintained in compartmentalized niches in lungs, distinct from populations in lymphoid ...
Brunner Stefan S Medical Department I, Klinikum Grosshadern, Ludwig-Maximilians-University, Marchioninistr. 15, 81377, Munich, Germany, - - 2013
Endogenous circulation of bone marrow-derived cells (BMCs) was observed in patients with dilated cardiomyopathy (DCM) who showed cardiac upregulation of Vascular Cell Adhesion Protein-1 (VCAM-1). However, the underlying pathophysiology is currently unknown. Thus, we aimed to analyze circulation, migration and G-CSF-based mobilization of BMCs in a murine model of virus-induced ...
- - 2013
Recent policy in the UK has emphasised the right of people with a learning disability to have more autonomy over their lives and to make decisions about their health care.
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Courses, events, grants, and awards to progress your career.
Niu Fubiao - - 2013
MYH3, whose function is to convert chemical energy to mechanical energy through ATP hydrolysis, is mainly expressed in skeletal muscle at various stages and is indispensable in the procedure of development of skeletal muscle and heart. In the study, genetic variations and genotypes of MYH 3 gene in a total ...
Moon Seong-Su - - 2013
There have been increasing concerns regarding health problems due to endocrine disrupting chemicals (EDCs). We investigated association of heavy metals, including lead, mercury, and cadmium, with metabolic syndrome (MS) and its individual components in the Korean population. Participants included 1,961 males and 1,989 females 20 years of age or older from ...
Dionisio Kathie L - - 2013
Measurements from central site (CS) monitors are often used as estimates of exposure in air pollution epidemiological studies. As these measurements are typically limited in their spatiotemporal resolution, true exposure variability within a population is often obscured, leading to potential measurement errors. To fully examine this limitation, we developed a ...
Zhang F - - 2013
In the present study we investigated the molecular mechanisms regulating the expression of RAR-related orphan receptor gamma t (RORγt), the central factor controlling interleukin (IL)-17 transcription and Th17 differentiation. In key studies, we found that cells from mice with major deletions of E-protein transcription factors, E2A and HEB, display greatly ...
- - 2013
The benefits of mammography screening remain controversial, with some studies suggesting that it leads to over-diagnosis and unnecessary treatment.
Colwell Ginny - - 2013
Increasing the probability of getting promoted usually starts long before the job advertisement appears.
Siao Derrick - - 2013
Helicobacter pylori has been causally linked to a number of diseases, including peptic ulcer disease, gastric adenocarcinoma, mucosa-associated lymphoid tissue lymphoma, and dyspepsia. It is the most prevalent bacterial pathogen in humans, and while the overall prevalence in the United States is about 30 %, the distribution is heterogeneous amongst different ...
Arena Salvatore - - 2013
Intranuclear inclusions (ICI) represent one cytological feature suggestive of malignancy. The aims of this study are (1) to correlate ICI with size and echogenicity of the thyroid nodules that, at fine-needle aspiration cytology (FNAC), are suspiciously malignant (THY4) or malignant (THY5); and (2) to ascertain whether ICI alone or combined ...
Osváth Zoltán - - 2013
Metal-graphene interfaces generated by electrode deposition induce barriers or potential modulations influencing the electronic transport properties of graphene based devices. However, their impact on the local mechanical properties of graphene is much less studied. Here we show that graphene near a metallic interface can exhibit a set of ripples self-organized ...
Ouyang Suidong S Blood-Brain Barrier Group, Pennington Biomedical Research Center, Baton Rouge, Louisiana, - - 2014
The blood-brain barrier (BBB) is a regulatory interface between the central nervous system and the rest of the body. However, BBB changes in obesity and metabolic syndrome have not been fully elucidated. We hypothesized that obesity reduces energy metabolism in the cerebral microvessels composing the BBB, reflected by downregulation of ...
Day Karen - - 2013
Some students do not discover that they have dyslexia until they reach university and the realisation can be both a shock and a relief. Many develop good coping strategies and may not disclose their disability.
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