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Results 301 - 350 of 1255
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Thomas Rebecca - - 2013
Experiential purchases are differentiated from material purchases in terms of objective; experiential purchases serve the purpose of acquiring a life experience, while material purchases serve the purpose of acquiring an object. Research has demonstrated that experiential purchases are associated with more happiness than material purchases. The current study investigated two ...
Khallad Yacoub - - 2013
Sociodemographic (gender and socioeconomic status) and personality (dispositional self-consciousness) correlates of risk behavior (smoking, seatbelt nonuse, vehicular speeding) and physical symptom reporting were assessed in a sample of Jordanian college students. Statistically significant correlations were found between gender and both risk behavior and physical symptom reporting. Female participants were more ...
Ding Cody - - 2013
The purpose of the current study was to study grade level and gender differences in coping behaviors among Chinese students using a multidimensional scaling (MDS) single-ideal point model. In contrast to approaches that utilize the aggregated scores such as average scores, the MDS single-ideal point model makes use of individual ...
Brown T - - 2013
The National Institute for Health and Care Excellence (NICE) has issued multiple guidance for the first-line management of patients with lung cancer and recommends different combinations of chemotherapy treatments. This review provides a synthesis of clinical effectiveness and cost-effectiveness evidence supporting current guidance. To evaluate the clinical effectiveness and cost-effectiveness ...
Mount Adele - - 2013
It is thought that the development of vaccines for the treatment of infectious diseases and cancer is likely to be achieved in the coming decades. This is partially due to a better understanding of the regulatory networks connecting innate with adaptive immune responses. The innate immune response is triggered by ...
Fox Christopher B - - 2013
With the exception of alum, emulsion-based vaccine adjuvants have been administered to far more people than any other adjuvant, especially since the 2009 H1N1 influenza pandemic. The number of clinical safety and immunogenicity evaluations of vaccines containing emulsion adjuvants has correspondingly mushroomed. In this review, the authors introduce emulsion adjuvant ...
McElhaney Janet E - - 2013
The decrease in influenza vaccine efficacy in the elderly is associated with a decline in the stimulation of cell-mediated and cytotoxic T-lymphocyte responses required for clinical protection against influenza, and may be particularly problematic when this population is administered split-virus vaccines that lack conserved viral proteins. Adjuvants, which act through ...
Ireton Gregory C - - 2013
The last decade has seen an increased focus on the development of adjuvants for vaccines, and several novel adjuvants are now in licensed products or in late-stage clinical development. These advancements have been aided by the discovery of receptors and signaling pathways of the innate immune system and an increased ...
Vasilakos John P - - 2013
Small molecule Toll-like receptor (TLR) 7/8 agonists have demonstrated potential as vaccine adjuvants, since they directly activate APCs and can enhance both humoral and cellular immune responses, especially Th1 responses. Although the natural ligands for TLR7 and TLR8 are ssRNA, the vast majority of vaccine studies performed thus far have ...
Infante Peter F - - 2013
The cohort study of Pliofilm workers exposed to benzene has been used as a primary data source to estimate quantitative dose response for benzene-leukemia. Little attention has focused on the undercounting of leukemia deaths used in the analyses, nor on the behavior of the company toward the Pliofilm workers who ...
Li Yi-Cheng - - 2013
ABSTRACT. A developed temporal focusing-based multiphoton excitation system with additional patterned excitation and local laser control can provide high-throughput fabrication of three-dimensional gray-level biomicrostructures via two-photon cross-linking with rose bengal (RB) as the photoactivator. Multiple bovine serum albumin (BSA) structures of different concentrations were simultaneously achieved by selecting different pulse ...
Guevara Edgar - - 2013
ABSTRACT. The potential of intrinsic optical imaging and resting-state analysis under anesthetized conditions as a tool to study brain networks associated with epileptic seizures is investigated. Using an acute model of epileptiform activity, the 4-aminopyridine model in live mice, we observe the changes in resting-state networks with the onset of ...
Jeong Mi Suk - - 2013
The purpose of this study was to describe the psychosocial adjustment and health-related quality of life (HRQoL) in children who received hematopoietic stem cell transplantation (HSCT) and to examine the relationship of children's characteristics with psychosocial adjustment and HRQoL in South Korea. Participants were 53 children who survived at least ...
Stiehm E Richard - - 2013
Human immunoglobulin (IG) is used for IgG replacement therapy in primary and secondary immunodeficiency, for prevention and treatment of certain infections, and as an immunomodulatory agent for autoimmune and inflammatory disorders. IG has a wide spectrum of antibodies to microbial and human antigens. Several high-titered IGs are also available enriched ...
Arnold Donald M - - 2013
Drug-induced immune thrombocytopenia (DITP) is a challenging clinical problem that is under-recognized, difficult to diagnose and associated with severe bleeding complications. DITP may be caused by classic drug-dependent platelet antibodies (eg, quinine); haptens (eg, penicillin); fiban-dependent antibodies (eg, tirofiban); monoclonal antibodies (eg, abciximab); autoantibody formation (eg, gold); and immune complex ...
Alaqeel Ahmed M - - 2013
To determine the prevalence of symptoms and risk of obstructive sleep apnea (OSA) among patients with ruptured cerebral aneurysms. In this case-control study, a validated Arabic version of the Berlin Questionnaire (BQ) was administered to patients admitted to King Fahd Medical City, Riyadh, Saudi Arabia with cerebral aneurysms between January ...
Mishra Vipanchi - - 2013
Much of the prior research investigating the influence of cultural values on performance ratings has focused either on conducting cross-national comparisons among raters or using cultural level individualism/collectivism scales to measure the effects of cultural values on performance ratings. Recent research has shown that there is considerable within country variation ...
Campos-Serna Javier - - 2013
Gender inequalities in the exposure to work-related psychosocial hazards are well established. However, little is known about how welfare state regimes influence these inequalities. To examine the relationship between welfare state regimes and gender inequalities in the exposure to work-related psychosocial hazards in Europe, considering occupational social class. We used ...
Sato Yosuke - - 2013
ABSTRACT. The seizure onset zone (SOZ) and propagation pathways in supplementary motor area (SMA) seizures are difficult to identify because of the short duration and swift propagations of this seizure type. Herein, we studied ictal cerebral blood flow changes, seizure electrical activities, and clinical signs employing simultaneous near-infrared spectroscopy (NIRS) ...
Takahama Junior Ademar - - 2013
ABSTRACT. Actinic cheilitis (AC) is a potentially malignant disorder of the lips. Because of its heterogeneous clinical aspect, it is difficult to indicate representative biopsy area. The purpose of this study was to evaluate the usefulness of tissue autofluorescence in AC diagnosis. The system was composed of a 405-nm light-emitting ...
Li Yao - - 2013
ABSTRACT. Stroke is a worldwide medical emergency and an important issue in stroke research is looking for the early pathophysiological markers which can predict the severity of brain injury. Decreased cerebral blood flow (CBF) has been serving as the most important indicator of ischemic stroke. Particular attention is paid to ...
Yesmine Saquiba - - 2013
Antihypertensive and antidiabetic effects of stevia, Stevia rebaudiana (Asteraceae), have been demonstrated in several human and animal models. The current study aims to define stevia's role in modifying the electrophysiological and mechanical properties of cardiomyocytes, blood vessels, and gastrointestinal smooth muscle. Tissues from thoracic aorta, mesenteric arteries, ileum, and left ...
Bohlega Saeed A - - 2013
Drug-induced Parkinsonism must always be suspected when parkinsonian symptom like rigidity, tremor, or postural instability appear in patients receiving drug treatment. Indeed, drug-induced Parkinsonism is a frequent etiology of secondary Parkinsonism. The main causative drugs are antipsychotic, other neuroleptic drugs, and calcium-channel entry blockers. The risk associated with antipsychotics is ...
Zakareia Faten A - - 2013
To investigate the role of an apoptotic marker soluble fatty acid synthase (s-Fas) antigen in children with autism and its correlation to disease severity. The study was conducted between May 2011 and April 2012 at the Department of Physiology and Autism Research and Treatment Center (ARTC) at King Khalid University ...
Gaddikeri Santhosh - - 2013
To define MRI criteria for the presumptive diagnosis of Rathke cleft cyst (RCC). One hundred and three patient MRI scans suggesting RCC performed between January 2005 and January 2011 were retrospectively reviewed for indications, cyst location, T1 and T2 signal intensity, dimensions, encroachment on optic chiasm, enhancement pattern, and stability ...
Liu Xun-Can - - 2013
We describe a patient who underwent intracranial angioplasty and Solitaire stent placement for recanalization of a vertebrobasilar artery occlusion 2 months after symptom onset. Computed tomography angiography and digital subtraction angiography showed that both vertebral arteries and the proximal basilar artery were occluded. Balloon angioplasty was performed on a segment ...
Wu Tao - - 2013
Colon cancer may invade the adjacent organ in the absence of distant metastasis, which is called stage T4bM0 colon cancer according to the 7th edition of TNM staging system. It is not rare in clinical setting, and usually recognized intraoperatively. How to deal with this situation is a big challenge ...
Jiang Hong-Yuan - - 2013
To evaluate the perforation, circumferential resection margin (CRM) and postoperative perineal wound complications after extralevator abdominoperineal excision(ELAPE) and conventional abdominoperineal excision(APE) for low rectal cancer by using systematic review method. The Cochrane Library, PubMed, EMbase, CNKI and VIP database were searched for literatures in which ELAPE and APE were compared ...
Shen Zhong - - 2013
To evaluate the efficacy of modified Gant-Miwa procedure with anal encircling for adults with rectal prolapse. Clinical and follow-up data of 31 adult patients with rectal prolapse undergoing modified Gant-Miwa procedure with anal encircling procedure between September 2005 and January 2012 were retrospectively analyzed. Operations were successfully performed in these ...
Yu Xiao-Fen - - 2013
To explore the exfoliated cancer cell contamination in different surgical materials during the malignant gastrectomy. Ninety gastric cancer patients undergoing gastrectomy were prospectively enrolled in this study. The operation materials of these 90 gastrectomy were divided into 5 groups: surgical instruments(A), gloves for surgeons (B), gloves and gauzes of scrub ...
Li Shu-Guang - - 2013
To investigate the effect of andrographolide(AD) on proliferation, cell cycle and apoptosis of human gastric cells line BGC-823. MTT assay, flow cytometry and Annexin-V/PI double-staining flow cytometry assay were used to evaluate the effect of AD on proliferation, cell cycle and apoptosis of BGC-823 cells respectively. Optical microscope and transmission ...
Hall Cathy W - - 2013
The relation of self-compassion to physical and psychological well-being was investigated among 182 college students. The self-compassion scale was delineated into three composites, following the proposition by Neff that self-compassion consists of three main components: self-judgment versus self-kindness (SJ-SK), a sense of isolation versus common humanity (I-CH), and over-identification versus ...
Petrovsky Nikolai - - 2013
Interview with Jenaid Rees, Commissioning Editor Nikolai Petrovsky is the Chairman and Research Director of Vaxine Pty Ltd, an Australian biotech company that specializes in novel vaccine adjuvants. He also holds the position of Director of Endocrinology at Flinders Medical Centre (Adelaide, Australia), Professor of Medicine at Flinders University, Vice ...
Andréasson Sven - - 2013
Interview by Jenaid Rees, Commissioning Editor Sven Andréasson has held the position of CEO for both pharmaceutical and biotech companies for many years; he was the President and CEO of Active Biotech AB (Sweden) between 1999 and 2008, CEO of Beta-Cell NV (Belgium) until 2012 and currently works as CEO ...
Clegg Christopher H - - 2013
H5N1 is a highly pathogenic avian influenza virus that can cause severe disease and death in humans. H5N1 is spreading rapidly in bird populations and there is great concern that this virus will begin to transmit between people and cause a global crisis. Vaccines are the cornerstone strategy for combating ...
Moser Christian - - 2013
The basic concept of virosomes is the controlled in vitro assembly of virus-like particles from purified components. The first generation of influenza virosomes developed two decades ago is successfully applied in licensed vaccines, providing a solid clinical safety and efficacy track record for the technology. In the meantime, a second ...
Safitri Zen Irina - - 2013
Malaysia has partially banned the use of asbestos. The prohibition of asbestos building materials in schools, clinics, and hospitals built by government started in 1999. Since 2005, prohibition has also been applied to all government buildings. However, asbestos construction materials such as roof and ceiling tiles are still sold in ...
Haddadin Randa N - - 2013
Pharmaceutical manufacturing workers are exposed to significant amounts of product ingredients, including antibiotics. Such exposure could affect their nasal microflora. To assess the effect of exposure to various unidentified pharmaceutical ingredients in cephalosporin-manufacturing and non-cephalosporin plants on the nasal carriage of Staphylococcus spp. and their antibiotic resistance. Nasal swab samples ...
Yassi Annalee - - 2013
Although non-specific low back pain (LBP) is known to be multifactorial, studies from across the globe have documented their higher prevalence in nurses. This systematic review was conducted to ascertain whether this much-documented association constitutes a causal relationship, and whether there is a discernible threshold of exposures associated with this ...
Bista Baba - - 2013
ABSTRACT. This study aimed to nondestructively evaluate sealing performance of eight one-step self-etch adhesives (1-SEAs) using optical coherence tomography (OCT). The two-step self-etch adhesive (2-SEA) served as the control. Round tapered class-I cavities (D=4  mm, H=2  mm) were prepared in bovine incisors, treated with each adhesive (n=5), and restored with a flowable ...
Srinivasan Vivek J - - 2013
ABSTRACT. High-resolution angiography and total average blood flow measurements in the rat retina using optical coherence tomography (OCT) are presented. Recently, an en face integration method, which does not require explicit calculation of vessel angles, was introduced to calculate blood flow using Doppler OCT. Using this method, rapid two-dimensional scanning ...
Tanabe Paula - - 2013
Children with sickle cell disease (SCD) present to the emergency department (ED) with complex medical and behavioral health needs. Little research has been conducted to understand elements necessary to provide a comprehensive approach. We conducted 9 focus groups and 2 individual interviews with ED nurses, ED physicians, parents, 1 SCD ...
Wölfle Ute - - 2013
Ultraviolet radiation induces DNA damage and oxidative stress which can result in skin inflammation, photoaging, and photocarcinogenesis. The flavonoid luteolin that is present in high amounts in the dyers weld, Reseda luteola, is one of the most potent antioxidative plant metabolites and also has ultraviolet-absorbing properties.The aim of this study ...
McCarthy Leo J - - 2013
Paul Holland began his career in transfusion medicine in 1963 as an assistant to Dr. Paul Schmidt in the Blood Bank at the National Institutes of Health (NIH). He served at the NIH for 20 years and retired in 1983 with the rank of Captain in the Public Health Service. ...
Mustafa Ayman G - - 2013
Traumatic brain injury (TBI) is considered an epidemic that continues to compromise the welfare of humankind. Despite the extensive efforts invested in countering this clinical health problem, current clinical science and technology still fall short of providing a pharmacological cure for TBI rendering tens of thousands of TBI patients vulnerable ...
Suresh Palle - - 2013
To evaluate the effect of leucine and genistein on the dopaminergic system in a rat model of schizophrenia. Behavioral effects of leucine and genistein on apomorphine induced stereotyped behavior, haloperidol induced catalepsy, foot shock induced aggression, and apomorphine induced locomotor activity were conducted. In each of these tests, the leucine ...
Unal Yasemin - - 2013
To define a new primitive reflex named the buccopalpebral reflex (BPR), and to investigate this reflex clinically and neurophysiologically in patients with Parkinson disease. This prospectively designed study included 17 patients, 9 BPR positive patients, and 8 BPR negative patients in Ankara Research and Training Hospital, Ankara, Turkey, and was ...
Niu Yin - - 2013
Arteriovenous malformations (AVMs) of the orbit are rare and are thought to be congenital. They can grow slowly or in a delayed fashion after a prolonged period of quiescence if there is a hemodynamic balance between the in-flow and the out-flow vessels. However, once the balance is destroyed, orbital AVMs ...
Rappuoli Rino - - 2013
Interview by Jenaid Rees, Commissioning Editor Rino Rappuoli is the Global Head of Vaccines Research at Novartis Vaccines & Diagnostics (Siena, Italy). Previously, he was Head of R&D (Sclavo, Italy), and then Head of Vaccine Research and Chief Scientific Officer at Chiron Corporation (CA, USA). Rappuoli earned his PhD in ...
Chen Lin - - 2013
Digestive tract reconstruction is the main part of gastrointestinal surgery. With the rapid development of technology and widely application in stapling device, more and more surgeons are using stapled anastomosis. Stapled anastomosis is associated with shorter operating time and hospital stay than hand-sewn anastomosis. However, it is not easy to ...
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