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Results 451 - 500 of 1202
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Phillies George D J - - 2013
The objective of this paper is to correct an error in analyses of quasielastic scattering spectra. The error invokes a valid calculation under conditions in which its primary assumptions are incorrect, which results in misleading interpretations of spectra. Quasielastic scattering from dilute probes yields the incoherent structure factor g((1s))(q, t) ...
Harmandaris Vagelis - - 2013
The effect of self-concentration and intermolecular packing on the dynamics of polyisoprene (PI)/polystyrene (PS) blends is examined by extensive atomistic simulations. Direct information on local structure of the blend system allows a quantitative calculation of self- and effective composition terms at various length scales that are introduced to proposed models ...
Berezovska Ganna - - 2013
Recent advances in computational power and simulation programs finally delivered the first examples of reversible folding for small proteins with an all-atom description. But having at hand the atomistic details of the process did not lead to a straightforward interpretation of the mechanism. For the case of the Fip35 WW-domain ...
Wang Zhisong - - 2013
Directional motion of nanoscale motors and driven particles in an isothermal environment costs a finite amount of energy despite zero work as decreed by the 2nd law, but quantifying this general limit remains difficult. Here we derive a universal equality linking directional fidelity of an arbitrary nanoscale object to the ...
Ngai K L - - 2013
A current focus in studies of the glass transition is the role of dynamic heterogeneities. Although these efforts may clarify the origin of the spectacular change in properties of liquids approaching vitrification, we point out that a seemingly related phenomenon - thermorheological complexity in polymers - must involve different mechanisms. ...
Builth-Williams J D - - 2013
Triple differential cross section measurements for the electron-impact ionization of the highest occupied molecular orbitals of tetrahydropyran and 1,4-dioxane are presented. For each molecule, experimental measurements were performed using the (e,2e) technique in asymmetric coplanar kinematics with an incident electron energy of 250 eV and an ejected electron energy of ...
Roy Susmita - - 2013
Experimental and simulation studies have uncovered at least two anomalous concentration regimes in water-dimethyl sulfoxide (DMSO) binary mixture whose precise origin has remained a subject of debate. In order to facilitate time domain experimental investigation of the dynamics of such binary mixtures, we explore strength or extent of influence of ...
Shandilya Bhavesh K - - 2013
The selective control of O-H/O-D bond dissociation in reduced dimensionality model of HOD molecule has been explored through IR+UV femtosecond pulses. The IR pulse has been optimized using simulated annealing stochastic approach to maximize population of a desired low quanta vibrational state. Since those vibrational wavefunctions of the ground electronic ...
Chatterley Adam S - - 2013
Photodissociation dynamics after excitation of the à state ν'2 = 4 (umbrella) level of ammonia are investigated using ultrafast time-resolved velocity map ion imaging (TR-VMI). These studies extend upon previous TR-VMI measurements [K. L. Wells, G. Perriam, and V. G. Stavros, J. Chem. Phys. 130, 074308 (2009)], which reported the ...
Solano C J F - - 2013
The structure and dynamics of N-butyl-N-methyl pyrrolidinium(+) bis([tri]fluoro[methane]sulfonyl)imide(-) (PYR14 (+)-[T]FSI(-)) ionic liquids doped with Li(T)FSI are investigated by combining experimental measurements to molecular dynamics simulations. The polarizable force field calculations indicate that the lithium cations are coordinated by (T)FSI anion oxygens forming lithium adducts stabilized over a large temperature range ...
Harada Ryuhei - - 2013
Parallel Cascade Selection Molecular Dynamics (PaCS-MD) is proposed as a molecular simulation method to generate conformational transition pathway under the condition that a set of "reactant" and "product" structures is known a priori. In PaCS-MD, the cycle of short multiple independent molecular dynamics simulations and selection of the structures close ...
Shih Orion - - 2013
The formation of like-charge guanidinium-guanidinium contact ion pairs in water is evidenced and characterized by X-ray absorption spectroscopy and first-principles spectral simulations based on molecular dynamics sampling. Observed concentration-induced nitrogen K-edge resonance shifts result from π∗ state mixing and the release of water molecules from each first solvation sphere as ...
Lee Song Hi - - 2013
Transport and recombination of hydrogen and hydroxide ions along a hydrogen-bonded water wire are studied by molecular dynamics simulation using a dissociating model for water. The results are compared with a recent CP-MD study of neutralization in bulk water [A. Hassanali, M. K. Prakrash, H. Eshet, and M. Parrinello, Proc. ...
Zhu Maximillian M Department of Chemistry, University of Cambridge, Cambridge CB2 1EW, United - - 2013
The aggregation of intrinsically disordered peptides and proteins is associated with a wide range of highly debilitating neurological and systemic disorders. In this work we explored the potential of a structure-based drug discovery procedure to target one such system, the soluble monomeric form of the Aβ42 peptide. We utilised for ...
Lao Ka Un KU Department of Chemistry and Biochemistry, The Ohio State University, Columbus, Ohio 43210, - - 2013
We recently introduced a low-cost quantum chemistry method for computing intermolecular interactions, combining a monomer-based self-consistent field calculation (the "explicit polarization" method, XPol) with pairwise-additive symmetry adapted perturbation theory (SAPT). The method uses Kohn-Sham (KS) orbitals in the SAPT formalism but replaces the SAPT dispersion and exchange-dispersion terms with empirical ...
Principi Mariabeatrice M Gastroenterology Unit, Department of Emergency and Organ Transplantation, University of Bari, 70124 Bari, - - 2013
To assess the safety and effect of the supplementation of a patented blend of dietary phytoestrogens and insoluble fibers on estrogen receptor (ER)-β and biological parameters in sporadic colonic adenomas. A randomized, double-blind placebo-controlled trial was performed. Patients scheduled to undergo surveillance colonoscopy for previous sporadic colonic adenomas were identified, ...
Bouwens Mariëlle W E MW Division of Gastroenterology and Hepatology, Department of Internal Medicine, Maastricht University Medical Center, 6202 AZ Maastricht, The - - 2013
To examine performances regarding prediction of polyp histology using high-definition (HD) i-scan in a group of endoscopists with varying levels of experience. We used a digital library of HD i-scan still images, comprising twin pictures (surface enhancement and tone enhancement), collected at our university hospital. We defined endoscopic features of ...
Fidder Herma H HH Department of Gastroenterology and Hepatology, University Medical Center Utrecht, 3508 GA Utrecht, The Netherlands. - - 2013
To investigate adherence rates in tumor necrosis factor-α (TNF-α)-inhibitors in Crohn's disease (CD) and rheumatoid arthritis (RA) by systematic review of medical literature. A structured search of PubMed between 2001 and 2011 was conducted to identify publications that assessed treatment with TNF-α inhibitors providing data about adherence in CD and ...
Watanabe Kazuhiro K Department of Gastroenterology and Hepatology, National Center for Global Health and Medicine, Tokyo 162-8655, - - 2013
To validate the usefulness of screening endoscopy findings for predicting Helicobacter pylori (H. pylori) infection status. H. pylori infection status was determined by histology, serology, and the urea breast test in 77 consecutive patients who underwent upper endoscopy. Based on the findings, patients were categorized as H. pylori-uninfected, -infected, or ...
Evans Jonathan D JD The Liver Unit, The Queen Elizabeth Hospital, Edgbaston, Birmingham B15 2TH, United - - 2013
Development of oedema and hypoproteinaemia in a liver transplant recipient may be the first signs of graft dysfunction and should prompt a full assessment. We report the novel case of a patient who, years after liver transplantation developed a functional blind loop in an incisional hernia, which manifested as oedema ...
Kaemmerer Elke E Department of Pediatrics and Institute of Pathology, RWTH Aachen University, D-52074 Aachen, - - 2013
Crohn's disease (CD), a variant of chronic inflammatory bowel disease, frequently affects the terminal ileum and coecal region. The clinical symptoms are often subtle and depend on the inflammatory activity of disease. In women of child-bearing age, florid intestinal endometriosis can simulate CD. Moreover, current pathophysiological concepts include intestinal endometriosis ...
Ji Jeong-Seon JS Division of Gastroenterology, Department of Internal Medicine, Incheon St. Mary's Hospital, The Catholic University of Korea College of Medicine, Incheon 403-720, South - - 2013
Endoscopic band ligation (EBL) is the preferred endoscopic technique for the endoscopic treatment of acute esophageal variceal bleeding. EBL has also been used to treat nonvariceal bleeding. Recently, Han et al demonstrated that EBL can be a feasible and safe alternate technique for the management of iatrogenic gastric perforation especially ...
Steele Scott R SR Department of Surgery, Madigan Army Medical Center, Madigan Health System, Tacoma, WA 98431, USA. - - 2013
Despite multiple efforts aimed at early detection through screening, colon cancer remains the third leading cause of cancer-related deaths in the United States, with an estimated 51000 deaths during 2013 alone. The goal remains to identify and remove benign neoplastic polyps prior to becoming invasive cancers. Polypoid lesions of the ...
Coskun Mehmet M Department of Gastroenterology, Medical Section, Herlev Hospital, University of Copenhagen, DK-2730 Herlev, Denmark. - - 2013
To use microarray-based miRNA profiling of colonic mucosal biopsies from patients with ulcerative colitis (UC), Crohn's disease (CD), and controls in order to identify new potential miRNA biomarkers in inflammatory bowel disease. Colonic mucosal pinch biopsies from the descending part were obtained endoscopically from patients with active UC or CD, ...
Ishihara Ryu R Department of Gastrointestinal Oncology, Osaka Medical Center for Cancer and Cardiovascular Diseases, Osaka 537-8511, Japan. - - 2013
To investigate the reasons for the occurrence of the pink-color sign of iodine-unstained lesions. In chromoendoscopy, the pink-color sign of iodine-unstained lesions is recognized as useful for the diagnosis of esophageal squamous cell carcinoma. Patients with superficial esophageal neoplasms treated by endoscopic resection were included in the study. Areas of ...
Wang Wen-Fei WF School of Biosciences, University of Nottingham, Sutton Bonington Campus, Loughborough, Leics LE12 5RD, United - - 2013
To investigate Krüppel-like factor 8 (KLF8) expression in gastric cancer and its relationship with angiogenesis and prognosis of gastric cancer. One hundred and fifty-four patients with gastric cancer who underwent successful curative resection were retrospectively enrolled in the study. Fifty tumor-adjacent healthy gastric tissues (≥ 5 cm from the tumor ...
Will Uwe U Department of Gastroenterology, Municipal Hospital, D-07548 Gera, Germany. - - 2013
To investigate the clinical value of endoscopic papillectomy indicated by feasibility and safety of the procedure in various diseases of the papilla in a representative number of patients in a setting of daily clinical and endoscopic practice and care by means of a systematic prospective observational study. Through a defined ...
Katsaragakis Stylianos S 1(st) Department of Propaedeutic Surgery, Athens Medical School, Hippocratio Athens General Hospital, University of Athens, 11527 Attiki, - - 2013
To present a new technique of end-to-side, duct-to-mucosa pancreaticojejunostomy with seromuscular jejunal flap formation, and insertion of a silicone stent. We present an end-to-side, duct-to-mucosa pancreaticojejunostomy with seromuscular jejunal flap formation, and the insertion of a silicone stent. This technique was performed in thirty-two consecutive patients who underwent a pancreaticoduodenectomy ...
Wiernicka Anna A Department of Gastroenterology, Hepatology and Malnutrition, the Children's Memorial Health Institute, 04-730 Warsaw, - - 2013
To investigate the side effects of a zinc sulphate therapy in a cohort of Polish pediatric patients with Wilson's disease. We retrospectively analyzed a cohort of 53 pediatric patients with Wilson's disease treated at the Children's Memorial Health Institute in Warsaw, Poland between the years 1996 and 2011 with zinc ...
Wierzbicki Piotr M PM Department of Histology, Faculty of Medicine, Medical University of Gdansk, 80210 Gdansk, Poland. - - 2013
To investigate large tumor suppressor 1 (LATS1) expression, promoter hypermethylation, and microsatellite instability in colorectal cancer (CRC). RNA was isolated from tumor tissue of 142 CRC patients and 40 colon mucosal biopsies of healthy controls. After reverse transcription, quantitative polymerase chain reaction (PCR) was performed, and LATS1 expression was normalized ...
Lim Chul-Hyun CH Department of Internal Medicine, The Catholic University of Korea College of Medicine, Seoul 137-070, South - - 2013
To evaluate the effects of DA-9701 on the gastric emptying of a solid meal using the ¹³C-octanoic acid breath test in a mouse model. Male C57BL/6 mice aged > 8 wk and with body weights of 20-25 g were used in this study. The solid test meal consisted of 200 ...
Xu Xiang-Huai XH Department of Respiratory Medicine, Tongji Hospital, Tongji University School of Medicine, Shanghai 200065, - - 2013
To evaluate the efficacy and safety of baclofen for treatment of refractory gastroesophageal reflux-induced chronic cough (GERC) unresponsive to standard anti-reflux therapy. Sixteen patients with refractory GERC were given an 8-wk course of baclofen 20 mg three times a day as an add-on therapy to omeprazole. Changes in the cough ...
Mao Yu-Shan YS Department of Endocrinology and Metabolism, Affiliated Hospital of Medical College of Ningbo University, Ningbo 315020, Zhejiang Province, - - 2013
To investigate the prevalence and risk factors of polypoid lesions of the gallbladder (PLGs) in petrochemical employees in Ningbo, Zhejiang Province, China. All active and retired employees aged 20-90 years (n = 11098) of a refinery and chemical plant in eastern China were requested to participate in a health survey. ...
Lei Jian-Yong JY Liver Transplantation Center, West China Hospital of Sichuan University, Chengdu 610041, Sichuan Province, - - 2013
Our study aimed to compare the results of liver transplantation (LT) and liver resection (LR) in patients with hepatocellular carcinoma (HCC) that met the Milan criteria after successful downstaging therapy. From February 2004 to August 2010, a consecutive series of 102 patients were diagnosed with advanced-stage HCC that met the ...
Bettenworth Dominik D Department of Medicine B, University of Münster, D-48149 Münster, Germany. - - 2013
We report on a 24-year-old male patient with history of bloody diarrhea, abdominal pain and vomiting. Endoscopy revealed massive ulcerative discontinuous proctosigmoiditis with deep, sharply demarcated epithelial denudations and enterotoxigenic methicillin-resistant Staphylococcus aureus (MRSA) was detected in mucosal biopsies. After treatment with linezolide and steroids, a significant amelioration of colitis ...
Cotta-Pereira Ricardo Lemos RL Department of Surgery, Federal University of Rio De Janeiro State-UNIRIO, Rio de Janeiro, RJ 20270-004, Brazil. - - 2013
Unlike hepatic haemorrhage following blunt abdominal trauma, spontaneous abdomen bleeding is rare, even in the presence of a hepatocellular adenoma (HA) or carcinoma. However, the diagnosis of a tumour underlying a haematoma after liver trauma is unusual, especially when it occurs more after two years after the accident. Here, we ...
Ikeura Tsukasa T Third Department of Internal Medicine, Kansai Medical University, Osaka 573-1191, Japan. - - 2013
Endoscopic retrograde cholangiopancreatography (ERCP) using a double-balloon enteroscope (DBE) in patients with bowel reconstruction due to a previous abdominal surgery is now widely accepted. In particular, a short DBE, which has a 2.8-mm working channel and 152-cm working length, is useful for ERCP because of its good rotational and straightening ...
Lim Darryl D Department of General Surgery, Singapore General Hospital, Singapore 169608, - - 2013
Positron emission tomography (PET) using ¹⁸F-fluorodeoxyglucose (¹⁸F-FDG) is an imaging modality which reflects cellular glucose metabolism. Most malignant cells accumulate and trap ¹⁸F-FDG, allowing the visualisation of increased uptake. It is hence widely used to differentiate malignant from benign lesions. "False positive" findings of hepatic lesions have been described in ...
Ye Min-Feng MF Department of Gastrointestinal Surgery, Shaoxing People's Hospital, Shaoxing Hospital of Zhejiang University, Shaoxing 312000, Zhejiang Province, China. - - 2013
Hepatoid adenocarcinoma of the stomach (HAS) is a rare form of gastric cancer that has unique clinicopathological features and an extremely poor prognosis. Here, we report on three patients with suspected gastric cancer who were referred to our hospital. Gastrointestinal fiberscopy on the three patients revealed two lesions in the ...
Freeman Hugh J - - 2013
A 72-year-old male with an early stage "node-negative" sigmoid colon cancer developed 2 separate "node-negative" early stage colon cancers during a subsequent colonoscopy surveillance regimen, the first in the descending colon 7 years later, and the second in the cecum almost 14 years after the first cancer was resected. After ...
Reisinger Kostan W - - 2013
The therapeutic potential of long-term ketotifen in irritable bowel syndrome and postoperative ileus is currently under investigation. Ambiguous results of prolonged postoperative ketotifen use on gastrointestinal passage have been found. The current data point at a hampered gastrointestinal transit after prolonged postoperative ketotifen use in a rodent ileus induction model. ...
Yamamoto Daigo D Department of Chemical Engineering and Materials Science, Doshisha University, Kyoto 610-0321, Japan. - - 2013
Most of the current studies on nano∕microscale motors to generate regular motion have adapted the strategy to fabricate a composite with different materials. In this paper, we report that a simple object solely made of platinum generates regular motion driven by a catalytic chemical reaction with hydrogen peroxide. Depending on ...
Li Fang - - 2013
Many older adults with dementia are hospitalized for diagnoses other than dementia. We aimed to determine the prevalence of comorbid dementia among hospitalized older adults and evaluate its effects on their hospital course. This retrospective case-control study reviewed the hospital records of all adults aged over 60 years admitted to one ...
Schudlo Larissa C - - 2013
Objective. Near-infrared spectroscopy (NIRS) is an optical imaging technique that has recently been considered for brain-computer interface (BCI) applications. To date, NIRS-BCI studies have primarily made use of temporal features of brain activity, derived from the time-course of optical signals measured from discrete locations, to differentiate mental states. However, functional ...
Lankelma Jan - - 2013
Previous models for predicting tumor cell growth are mostly based on measurements of total cell numbers. The purpose of this paper is to provide a new simple mathematical model for calculating tumor cell growth focusing on the fraction of cells that is clonogenic. The non-clonogenic cells are considered to be ...
Nelson Peter T PT Sanders-Brown Center on Aging, University of Kentucky, Lexington, KY 40536, USA. - - 2013
Hippocampal sclerosis of aging (HS-Aging) is a causative factor in a large proportion of elderly dementia cases. The current definition of HS-Aging rests on pathologic criteria: neuronal loss and gliosis in the hippocampal formation that is out of proportion to AD-type pathology. HS-Aging is also strongly associated with TDP-43 pathology. ...
Goldenberg Georg - - 2013
In typical right-handed patients both apraxia and aphasia are caused by damage to the left hemisphere, which also controls the dominant right hand. In left-handed subjects the lateralities of language and of control of the dominant hand can dissociate. This permits disentangling the association of apraxia with aphasia from that ...
Oñativia Jon J Department of Electrical and Electronic Engineering, Imperial College London, South Kensington, London SW7 2AZ, UK. - - 2013
Inferring the times of sequences of action potentials (APs) (spike trains) from neurophysiological data is a key problem in computational neuroscience. The detection of APs from two-photon imaging of calcium signals offers certain advantages over traditional electrophysiological approaches, as up to thousands of spatially and immunohistochemically defined neurons can be ...
Zhang Xu X Institute of Biomedical Engineering, University of Science and Technology of China, Hefei, People's Republic of - - 2013
This study investigates the effect of the involuntary motor activity of paretic-spastic muscles on the classification of surface electromyography (EMG) signals. Two data collection sessions were designed for 8 stroke subjects to voluntarily perform 11 functional movements using their affected forearm and hand at relatively slow and fast speeds. For ...
Guitchounts Grigori G Department of Biology, Boston University, 24 Cummington Mall, Boston, MA 02215, - - 2013
Chronic neural recording in behaving animals is an essential method for studies of neural circuit function. However, stable recordings from small, densely packed neurons remains challenging, particularly over time-scales relevant for learning. We describe an assembly method for a 16-channel electrode array consisting of carbon fibers (<5 µm diameter) individually ...
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