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Results 351 - 400 of 1287
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McRae Marion E - - 2013
The Fontan procedure is used to treat various serious congenital heart defects. Although many people who have had the procedure live productively into adulthood, as they age, they face several health issues due to the physiology of the Fontan circulation. This article reviews the 4 types of Fontan procedures and ...
Corkery John M - - 2013
MDAI (5,6-methylenedioxy-2-aminoindane; 6,7-dihydro-5H-cyclopenta[f][1,3]benzodioxol-6-amine; 'sparkle'; 'mindy') is a psychoactive substance, sold primarily over the Internet and in 'head' shops as a 'legal high'. Synthesised and used as a research chemical in the 1990s, MDAI has structural similarities to MDMA (3,4-methylenedioxy-N-methylamphetamine) and shares its behavioural properties. Recreational use of MDAI appears to ...
Tabatabaie Morteza - - 2013
Introduction. Heart disease is one of the most common reasons of death in beta-thalassemia major. A few studies have been done in children about blood pressure changes. The aim of this study was to assess hemodynamic changes by ambulatory blood pressure monitoring (ABPM). Materials and Methods. In this cross-sectional study, ...
Crofford Rebekah - - 2013
In this study the authors examine the individual and family characteristics of youth (N = 105) admitted over a five year period to a day school treatment program in a western New York community. All had exhausted alternative school placements within their home school districts and had a history of ...
Cruz Ernesto - - 2013
Phantom limb pain is a frequent sequela of amputation. A high prevalence of residual limb pain and back pain also exists among amputees. We present a case of a new-onset severe phantom limb pain resulting from a metastatic spinal mass in an 81-year-old patient with a history of malignant sarcoma ...
Monczewski Lisa L University Hospitals Case Medical Center, Seidman Cancer Center, Cleveland, OH, - - 2013
Bone is the third most common site of cancer metastasis resulting in pain and other serious morbidities that can affect one's quality of life. The orthopaedic patient with bone metastasis faces many challenges and has complex nursing care needs. Managing care involves astute assessment skills, knowledge of treatments including medication, ...
Ruth Terrance - - 2013
In this article the authors analyze relevant and reliable evidence on the effects of the preferable treatment customized to each social work client. In doing so, the authors look at four major standards of evidence: (1) evidence-based practice, (2) collaboration models (i.e., the Cochrane Collaboration and the Campbell Collaboration), (3) ...
Parrott Andrew C AC Department of Psychology, Swansea University, Swansea, South Wales, UK. - - 2013
This paper aimed to review how scientific knowledge about the human psychobiology of MDMA has developed over time. In this paper, the empirical findings from earlier and later studies will be reviewed. When MDMA was a 'novel psychoactive substance', it was not seen as a drug of abuse, as it ...
Lingappan Krithika - - 2013
Neonatal sepsis and necrotizing enterocolitis (NEC) are associated with significant mortality and morbidity. Inflammation secondary to sepsis and NEC increases morbidity, especially those related to the lung, brain and eye. Therapeutic strategies that target inflammation and decrease the emergence of antibiotic resistance are urgently needed. Lactoferrin (Lf) is a multifunctional ...
Anderson Kimberly G - - 2013
Calcific uremic arteriolopathy is a little understood diagnosis of increasing prevalence seen predominantly in patients with chronic kidney disease, particularly those who are approaching end-stage renal disease, who are undergoing renal dialysis, and who have secondary hyperparathyroidism. Calcific uremic arteriolopathy affects women more frequently than men, at a ratio of ...
Kirkham Paul A - - 2013
Oxidative stress is now recognized as a major predisposing factor in the pathogenesis of COPD. Existing therapies for COPD are ineffective at halting disease progression, with bronchodilators being the mainstay of pharmacotherapy, providing symptomatic relief only. It is, therefore, important for a better understanding of the underlying mechanisms by which ...
Papanti Duccio - - 2013
The use of synthetic cannabimimetics (SC; "spice" drugs) is increasing, especially among teenagers and young adults. In parallel with this, the number of studies describing intoxication episodes associated with psychotic symptoms in SC users is growing. We present both a systematic review of the related literature and a case report, ...
Ganji Mohammad Reza - - 2013
Introduction. As an immunosuppressive treatment, cyclosporine carries a significant risk of nephrotoxicity. In this study, we assessed the safety and efficacy of sirolimus conversion in our kidney transplant recipients. Materials and Methods. Sirolimus conversion in 99 kidney transplant recipients was evaluated. Serum level of creatinine, glomerular filtration rate (GFR), and ...
Corazza Ornella - - 2013
The recent emergence of new psychoactive compounds (novel psychoactive substances (NPS)) has raised prominent challenges in the fields of drug policy, substance use research, public health and service provision. The Recreational Drugs European Network project, funded by the European Commission, was implemented to improve the information stream to young people ...
Stothard J Russell - - 2013
Preventive chemotherapy campaigns against schistosomiasis have progressively scaled-up during the last decade, administering single standard dose praziquantel (40 mg/kg) treatments to millions of African children. Steps taken in securing international advocacy and national level implementation are traced to highlight an international treatment platform set for further expansion, including surveillance of schistosomiasis, ...
Pérez-Riera Andrés Ricardo - - 2013
The electrocardiogram is an important tool for the initial diagnostic suspicion of hypertrophic cardiomyopathy in any of its forms, both in symptomatic and in asymptomatic patients because it is altered in more than 90 percent of the cases. Electrocardiographic anomalies are more common in patients carriers of manifest hypertrophic cardiomyopathy ...
Safaei Asl Afshin - - 2013
Hypercalciuria is the most common identifiable metabolic cause of calcium kidney calculus disease. Idiopathic hypercalciuria is defined as hypercalciuria with normal serum electrolytes levels in the absence of any known underlying disease responsible for increased urinary calcium excretion. The aim of the present survey was to study the prevalence of ...
Mohd Fauzi Fazlin - - 2013
This study exemplifies computer-aided (in silico) approaches in assessing the risks of new psychoactive substances emerging in the European Union. In this work, we (i) consider the potential of Ostarine exhibiting psychoactivity and (ii) anticipate potential activities and toxicities of 4-methylamphetamine. The approach, termed in silico target prediction, suggests potential ...
Lawson Jennifer - - 2013
In this article the authors examine the evidentiary status of the Court Appointed Special Advocates (CASA) program through a review of current research findings and a critical analysis of the study methodologies used to produce those findings. Due to the equivocal research findings and widespread methodological weaknesses (most notably selection ...
Foris Vasile - - 2013
Pulmonary hypertension (PH) is a hemodynamic condition that has a poor prognosis and can lead to right-sided heart failure. It may result from common diseases such as left-sided heart or lung disease or may present as the rare entity of idiopathic pulmonary arterial hypertension. Biomarkers that specifically indicate the pathologic ...
Winstock Adam R - - 2013
A wide range of synthetic cannabinoid products have recently become available through the Internet and shop fronts across the globe. Concerns about the consequences of their use have been prompted by increasing reports of emergency department presentations. An anonymous global online survey was conducted using a research tool based on ...
Sharifian Mostafa - - 2013
Introduction. Adrenomedullin (AM) is a 52-amino acid peptide that causes vasodilatation by increased synthesis of nitric oxide. Its production by different cells such as cardiac myocytes, smooth muscle, endothelial, and oncogenic cells is stimulated by inflammatory processes. It has been shown that in the presence of inflammation in the urinary ...
Mann Aaron - - 2013
With the enactment of the Second Chance Act in 2008, social workers have a greater opportunity for intervention to break the cycle of recidivism. To develop interventions, however, social workers require profiles of incarcerated people and their perceived human service needs. Unfortunately, previous research has focused on prison and not ...
Lee Jacob - - 2013
Falls and their associated injuries profoundly impact health outcomes, functional independence, and health care expenses, particularly for the ever-increasing elderly population. This systematic search and review assessed the current evidence for the role of fall screening assessments. To review the current evidence for fall risk screening assessments in community-dwelling (outpatient), ...
Bauer Michael - - 2013
Abstract Objectives. This 2013 update of the practice guidelines for the biological treatment of unipolar depressive disorders was developed by an international Task Force of the World Federation of Societies of Biological Psychiatry (WFSBP). The goal has been to systematically review all available evidence pertaining to the treatment of unipolar ...
Simonato Pierluigi - - 2013
Novel psychoactive substances (NPS; a.k.a. 'legal highs' or 'smart drugs') are advertised online as 'safe' and 'legal' natural/synthetic analogues of controlled illicit drugs. However, only little research has been carried out in identifying the health professionals' knowledge and expertise relating to the intake of these compounds. Data presented here refer ...
Basiratnia Mitra - - 2013
Introduction. Obesity is a growing problem worldwide and is likely a major cause of the increased prevalence of high blood pressure in children. The aim of this study was to investigate the frequency of pediatric obesity and its association with hypertension in a sample of children and adolescents in Fars ...
Painter Kirstin - - 2013
Childhood trauma due to physical abuse, neglect, or sexual abuse is a serious problem in the United States. Trauma can result in disruption or injury to the developing brain and lead to neurodevelopmental deficits that affect a child's functioning and can result in lifelong problems. Research has provided insight into ...
Kutscher Beth - - 2013
Tenet Healthcare Corp.'s acquisition of Vanguard Health Systems is a sign the investor-owned chain is willing to take a chance on alternative payment models such as accountable care organizations. There's no certainty that ACOs will deliver the improvements on quality or cost savings, but Vanguard Vice Chairman Keith Pitts, left, ...
de Melo Wanessa Cma - - 2013
Microbial biofilms are responsible for a variety of microbial infections in different parts of the body, such as urinary tract infections, catheter infections, middle-ear infections, gingivitis, caries, periodontitis, orthopedic implants, and so on. The microbial biofilm cells have properties and gene expression patterns distinct from planktonic cells, including phenotypic variations ...
Otukesh Hasan - - 2013
Recently, the role of B cells in the pathogenesis of nephrotic syndrome is explained by some researchers. It has also been shown that the anti-CD20 antibody, rituximab, may be an option in the treatment of these patients. In this systematic review, we performed extensive search and identified studies on rituximab ...
Powers Joelle D - - 2013
Presumably, schools desiring larger effects from an empirically based program might be willing to allocate greater resources for the purchase and implementation of the intervention. However, while it may seem intuitive that more expensive programs generate greater change in student outcomes, there is currently a lack of evidence supporting such ...
Atar Shaul S Department of Cardiovascular Medicine, The Western Galilee Hospital in Nahariya, Nahariya, Israel. - - 2013
Several new oral anticoagulants have been approved for thromboembolism prevention in patients with nonvalvular atrial fibrillation. However, they are not yet approved for anticoagulation use in patients with prosthetic mechanical valves, and no randomized data have been published so far on their safety of use in these patients. We present ...
Goldenberg Gary - - 2013
Keloids are benign growths characterized by excessive collagen formation. The treatment of keloid scars remains a challenging clinical dilemma for both patients and providers. Intralesional cryosurgery has emerged as a safe and effective new treatment by destroying the hypertrophic scar tissue with minimal damage to the skin surface.
López José - - 2013
Recent studies have found increased long-term cardiovascular morbidity after off-pump coronary artery bypass surgery (OPCAB). We evaluated the efficacy and safety of dual antiplatelet therapy (DAT) in the prevention of cardiovascular events at two years after OPCAB surgery. Retrospective study that included all patients that underwent OPCAB surgery in our ...
Pappalardo Federico - - 2013
The Levitronix CentriMag is approved in Europe for 30 days as uni- or biventricular support in acute heart failure as a bridge to recovery, bridge to heart transplantation or to a long-term left ventricular assist device (LVAD). We report the case of a patient who was supported with the same ...
Grosset Jacques H - - 2013
Evaluation of: Diacon AH, Dawson R, Von Groote-Bidlingmaier F et al. Randomized dose-ranging study of the 14-day early bactericidal activity of bedaquiline (TMC207) in patients with sputum microscopy smear-positive pulmonary tuberculosis. Antimicrob. Agents Chemother. 57(5), 2199-2203 (2013). During the past decade considerable efforts have been made to develop and register ...
Nouri Masoumeh - - 2013
It is not clear whether the presence and degree of chronic ischemic mitral regurgitation (IMR) in patients with left ventricular (LV) dysfunction are related to LV dysfunction, local LV remodeling or mitral valve deformation. We sought to establish the strongest determinants of IMR severity in patients with LV dysfunction and ...
Kumar Anant - - 2013
Training needs assessments are pivotal for any capacity building program. Building capacity of service providers and staff involved in HIV/AIDS intervention programs is crucial because of the distinct nature of such programs. It requires specific knowledge, skills, and attitudes that are of utmost importance, influencing the reach of the program ...
Manchester Carol S - - 2013
Multiple endocrine neoplasia (MEN) is an array of tumors found in various endocrine glands throughout the human body. A wide spectrum of clinical manifestations accompanies this syndrome. The complexities of the glandular function and subtle development of symptoms can cause the diagnosis to be missed, and individuals with MEN can ...
Leflar Robert B - - 2013
New rules and methods for medical injury dispute resolution have been launched in New Hampshire and New York, and demonstration projects are underway elsewhere. This article describes major medical malpractice reforms undertaken and proposed in recent years. Reforms are classified as (1) liability-limiting initiatives favoring health-care providers; (2) procedural innovations ...
St John-Smith Paul - - 2013
In this article, ontogenetic and phylogenetic causes of drug abuse and links to human emotional development are considered. Some evolutionary perspectives (e.g. that under certain conditions, consumption of otherwise toxic alkaloids may confer both physical and cultural advantages) are reviewed. As described in the 'mismatch theory', the capacity of the ...
Vernick William J - - 2013
To evaluate the accuracy of Doppler-derived transmitral valve gradients immediately after mitral valve repair by comparing them with near simultaneously obtained direct catheter gradients. A prospective study. A tertiary care medical center. Twenty elective adult surgical patients presenting for mitral valve repair surgery. Mitral valve surgery proceeded in standard fashion ...
Hundalani Shilpa - - 2013
Invasive fungal infections due to Candida are the third most common late-onset infection in infants born with birth weight <1500 g. Invasive candidiasis in infants born with birth weight <1000 g is associated with a 30% mortality and with neurodevelopmental impairment in more than half the survivors. A high degree of suspicion ...
Unver Bayram B Department of Orthopedic Physiotherapy, School of Physical Therapy and Rehabilitation, Dokuz Eylül University, Izmir, - - 2013
Although studies determinate that the tourniquet and high tourniquet pressure applications lead to several complications and decelerate the rehabilitation, there was not any study investigating the effects of tourniquet pressure on rehabilitation outcomes and postoperative complications. To investigate the effects of the minimal and conventional tourniquet inflation pressures application on ...
Hampton Jessica - - 2013
Although thyroid dysfunction will develop in more than 12% of the US population during their lifetimes, true thyroid emergencies are rare. Thyroid storm and myxedema coma are endocrine emergencies resulting from thyroid hormone dysregulation, usually coupled with an acute illness as a precipitant. Careful assessment of risk and rapid action, ...
Mukhopadhyay Sanjay - - 2013
Hut lung is a pneumoconiosis caused by exposure to smoke derived from biomass fuels used for cooking in poorly ventilated huts. We report, to our knowledge, the first analysis of the dust deposited in the lungs in hut lung by scanning electron microscopy with energy dispersive x-ray spectroscopy (SEM/EDS). A ...
Torok Helen M - - 2013
Oral antibiotics continue to play an important role in the treatment of moderate-to-severe acne. Minocycline is widely used in moderate-to-severe acne. Minocycline has anti-inflammatory properties, activity against Propionibacterium acnes and lipophilicity. An extended-release formulation of minocycline has been introduced. Extended-release minocycline is not bioequivalent to nonmodified release minocycline products and ...
Douglas Emily M - - 2013
Annually, 1,000-2,000 child welfare workers experience the death of a child client. The child welfare field has paid increasing attention to the impact of workplace trauma events on the psychological distress of child welfare workers. In this article the author assesses the relationship between experiencing a maltreatment fatality and workers' ...
Kong Lingbing L Department of Chemistry, University of Oxford, Chemical Research Laboratory, Mansfield Road, Oxford OX1 3TA, - - 2013
Capsular polysaccharides form the outermost protective layer around many Gram-negative bacteria. Antibiotics aimed directly at weakening this layer are not yet available. In pathogenic Escherichia coli E69, a protein, Wza, forms a pore in the outer membrane that transports K30 capsular polysaccharide from its site of synthesis to the outside ...
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