Search Results
Results 301 - 350 of 1282
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Hwang Jungwon - - 2013
Pathogenic and commensal bacteria that experience limited nutrient availability in their host have evolved sophisticated systems to catabolize the mucin sugar N-acetylneuraminic acid, thereby facilitating their survival and colonization. The correct function of the associated catabolic machinery is particularly crucial for the pathogenesis of enteropathogenic bacteria during infection, although the ...
Xiao Yanling - - 2013
Osteoclasts (OCs) are bone-resorbing cells that are formed from hematopoietic precursors. OCs ordinarily maintain bone homeostasis, but they can also cause major pathology in autoimmune and inflammatory diseases. Under homeostatic conditions, receptor activator of nuclear factor kappa-B (RANK) ligand on osteoblasts drives OC differentiation by interaction with its receptor RANK ...
Tsien Roger Y - - 2013
A hypothesis and the experiments to test it propose that very long-term memories, such as fear conditioning, are stored as the pattern of holes in the perineuronal net (PNN), a specialized ECM that envelops mature neurons and restricts synapse formation. The 3D intertwining of PNN and synapses would be imaged ...
Mori S - - 2013
To evaluate the impact of variation in respiratory cycle between treatment planning and irradiation for pencil beam scanning and phase-controlled rescanning (PCR) on the resulting dose distribution, we conducted a simulation study based on four-dimensional CT (4DCT) data for lung cancer patients. 4DCT data were acquired for seven patients with ...
Mucci B - - 2013
Discrepancy meetings are an important aspect of clinical governance. The Royal College of Radiologists has published advice on how to conduct meetings, suggesting that discrepancies are scored using the scale: 0=no error, 1=minor error, 2=moderate error and 3=major error. We have noticed variation in scores attributed to individual cases by ...
Kim J Y - - 2013
To assess the properties of adrenal lesions with and without known primary cancer and investigate predictors for differential diagnosis between benign and malignant adrenal enlargement. This retrospective study used fluorine-18 fludeoxyglucose positron emission tomography (PET)/CT in 325 patients with adrenal lesions (229 with known primary cancer and 96 without primary ...
Dvir Shlomi S Departments of Computer Science and Applied Mathematics, Weizmann Institute of Science, Rehovot 76100, - - 2013
The 5'-untranslated region (5'-UTR) of mRNAs contains elements that affect expression, yet the rules by which these regions exert their effect are poorly understood. Here, we studied the impact of 5'-UTR sequences on protein levels in yeast, by constructing a large-scale library of mutants that differ only in the 10 ...
Pineda Jane - - 2013
Family processes are a risk factor for suicide but few studies target this domain. We evaluated the effectiveness of a family intervention, the Resourceful Adolescent Parent Program (RAP-P) in reducing adolescent suicidal behavior and associated psychiatric symptoms. A preliminary randomized controlled trial compared RAP-P plus Routine Care (RC) to RC only, ...
Karim Muhammad Ali - - 2013
The increasing prevalence of obesity has now become a global concern. Forecasts of its health and financial ramifications have prompted the need for effective interventions. Bariatric surgery is an effective measure to control obesity and its related comorbidities, but its high upfront costs have raised questions about its cost-effectiveness. In ...
Stringaris Argyris - - 2013
DSM-IV grants episodic irritability an equal status to low mood as a cardinal criterion for the diagnosis of depression in youth, yet not in adults; however, evidence for irritability as a major criterion of depression in youth is lacking. This article examines the prevalence, developmental characteristics, associations with psychopathology, and ...
Mueller Elizabeth R - - 2013
This review summarizes the recent clinical trials that address the abdominal approach for treatment of uterine or vaginal vault prolapse following hysterectomy. Open abdominal sacrocolpopexy (ASC) has improved anatomic and sexual functioning outcomes compared with the sacrospinous ligament suspension but this benefit comes with higher costs. Newer studies suggest that ...
McRae Marion E - - 2013
The Fontan procedure is used to treat various serious congenital heart defects. Although many people who have had the procedure live productively into adulthood, as they age, they face several health issues due to the physiology of the Fontan circulation. This article reviews the 4 types of Fontan procedures and ...
Manchester Carol S - - 2013
Multiple endocrine neoplasia (MEN) is an array of tumors found in various endocrine glands throughout the human body. A wide spectrum of clinical manifestations accompanies this syndrome. The complexities of the glandular function and subtle development of symptoms can cause the diagnosis to be missed, and individuals with MEN can ...
Kapitány-Fövény Máté - - 2013
In the past 25-30 years, a large number of synthetic and non-synthetic drugs have appeared on the recreational scene, but with the exception of 4-methylmethcathinone (mephedrone), none of these substances reached the popularity of ecstasy [3,4-methylenedioxy-N-methylamphetamine, (MDMA)]. Authors aimed to determine the subjective effects of mephedrone in order to understand how ...
Corazza Ornella - - 2013
The recent emergence of new psychoactive compounds (novel psychoactive substances (NPS)) has raised prominent challenges in the fields of drug policy, substance use research, public health and service provision. The Recreational Drugs European Network project, funded by the European Commission, was implemented to improve the information stream to young people ...
González Débora - - 2013
To know the pattern of use of new psychoactive substances (NPSs) in a Spanish sample of research chemical (RC) users and to deepen the RC user profile and risk reduction strategies employed. This study is a cross-sectional survey by means of a specific questionnaire. Recruitment was carried out at music ...
Corkery John M - - 2013
MDAI (5,6-methylenedioxy-2-aminoindane; 6,7-dihydro-5H-cyclopenta[f][1,3]benzodioxol-6-amine; 'sparkle'; 'mindy') is a psychoactive substance, sold primarily over the Internet and in 'head' shops as a 'legal high'. Synthesised and used as a research chemical in the 1990s, MDAI has structural similarities to MDMA (3,4-methylenedioxy-N-methylamphetamine) and shares its behavioural properties. Recreational use of MDAI appears to ...
Mohd Fauzi Fazlin - - 2013
This study exemplifies computer-aided (in silico) approaches in assessing the risks of new psychoactive substances emerging in the European Union. In this work, we (i) consider the potential of Ostarine exhibiting psychoactivity and (ii) anticipate potential activities and toxicities of 4-methylamphetamine. The approach, termed in silico target prediction, suggests potential ...
Winstock Adam R - - 2013
A wide range of synthetic cannabinoid products have recently become available through the Internet and shop fronts across the globe. Concerns about the consequences of their use have been prompted by increasing reports of emergency department presentations. An anonymous global online survey was conducted using a research tool based on ...
Otukesh Hasan - - 2013
Recently, the role of B cells in the pathogenesis of nephrotic syndrome is explained by some researchers. It has also been shown that the anti-CD20 antibody, rituximab, may be an option in the treatment of these patients. In this systematic review, we performed extensive search and identified studies on rituximab ...
de Melo Wanessa Cma - - 2013
Microbial biofilms are responsible for a variety of microbial infections in different parts of the body, such as urinary tract infections, catheter infections, middle-ear infections, gingivitis, caries, periodontitis, orthopedic implants, and so on. The microbial biofilm cells have properties and gene expression patterns distinct from planktonic cells, including phenotypic variations ...
Zakkerkish Mehrnoosh - - 2013
Introduction. The aim of this study was to determine the prevalence of albuminuria and its correlates and investigate disease management for patients with type 2 diabetes mellitus in Ahvaz. Materials and Methods. This was a cross-sectional study on the 350 patients with type 2 diabetes mellitus attending the Diabetes Clinic ...
Basiratnia Mitra - - 2013
Introduction. Obesity is a growing problem worldwide and is likely a major cause of the increased prevalence of high blood pressure in children. The aim of this study was to investigate the frequency of pediatric obesity and its association with hypertension in a sample of children and adolescents in Fars ...
Changizi Ashtiyani Saeed - - 2013
Introduction. This study aimed to investigate the effects of Rosa canina L fruit extracts on histological damages, oxidative stress, and functional disturbances induced by bilateral renal ischemia and reperfusion. Materials and Methods. Ischemia and reperfusion were induced on the kidneys of anesthetized male Sprague-Dawley rats. The rats in the reperfusion ...
Tayebi-Khosroshahi Hamid - - 2013
We report a 16-year-old previously healthy boy who was admitted to hospital with fever, constitutional symptoms, purpura, additive arthritis, dysentery, rapid progressive renal failure, resembling Henoch- Schuenlein purpura, accompanied with retropharyngeal abscess. Kidney biopsy revealed rapid progressive glomerulonephritis with crescent formation, without immune deposition in immune fluorescent study. Serologic study ...
Alawwa Izzat A - - 2013
Hypertension is very common in kidney transplant patients; however, severe and resistant cases should raise suspicion of secondary causes. Pheochromocytomas are rare but serious tumors because of their lethal hypertensive and possible malignant nature. The diagnosis is occasionally elusive, but prompt diagnosis and localization is essential for definitive surgical management. ...
Vernick William J - - 2013
To evaluate the accuracy of Doppler-derived transmitral valve gradients immediately after mitral valve repair by comparing them with near simultaneously obtained direct catheter gradients. A prospective study. A tertiary care medical center. Twenty elective adult surgical patients presenting for mitral valve repair surgery. Mitral valve surgery proceeded in standard fashion ...
Maeda Koichi - - 2013
Even mild paravalvular leakage (PVL) after transcatheter aortic valve replacement (TAVR) is associated with increased late mortality. Electrocardiogram-gated multi-slice computed tomography (MSCT) enables detailed aortic annulus assessment. We describe the impact of MSCT for PVL following TAVR. Congruence between the prosthesis and annulus diameters affects PVL; therefore, we calculated the ...
Alzahrani Haitham - - 2013
We describe the surgical management of a 35-year-old male with multiple coronary aneurysms and a diffuse form of supravalvular aortic stenosis who presented with acute myocardial infarction and left ventricular dysfunction. The patient underwent a Bentall procedure with left internal mammary artery to left anterior descending artery bypass grafting with ...
Pappalardo Federico - - 2013
The Levitronix CentriMag is approved in Europe for 30 days as uni- or biventricular support in acute heart failure as a bridge to recovery, bridge to heart transplantation or to a long-term left ventricular assist device (LVAD). We report the case of a patient who was supported with the same ...
Mann Aaron - - 2013
With the enactment of the Second Chance Act in 2008, social workers have a greater opportunity for intervention to break the cycle of recidivism. To develop interventions, however, social workers require profiles of incarcerated people and their perceived human service needs. Unfortunately, previous research has focused on prison and not ...
Painter Kirstin - - 2013
Childhood trauma due to physical abuse, neglect, or sexual abuse is a serious problem in the United States. Trauma can result in disruption or injury to the developing brain and lead to neurodevelopmental deficits that affect a child's functioning and can result in lifelong problems. Research has provided insight into ...
Ruth Terrance - - 2013
In this article the authors analyze relevant and reliable evidence on the effects of the preferable treatment customized to each social work client. In doing so, the authors look at four major standards of evidence: (1) evidence-based practice, (2) collaboration models (i.e., the Cochrane Collaboration and the Campbell Collaboration), (3) ...
Powers Joelle D - - 2013
Presumably, schools desiring larger effects from an empirically based program might be willing to allocate greater resources for the purchase and implementation of the intervention. However, while it may seem intuitive that more expensive programs generate greater change in student outcomes, there is currently a lack of evidence supporting such ...
Crofford Rebekah - - 2013
In this study the authors examine the individual and family characteristics of youth (N = 105) admitted over a five year period to a day school treatment program in a western New York community. All had exhausted alternative school placements within their home school districts and had a history of ...
Barwick Melanie - - 2013
Many children and adolescents with mental health problems do not receive the treatment they need. Unmet need raises questions about specific barriers that may prevent service use, and/or the characteristics of children and families who are less likely to receive care. Brief interventions or single-session psychotherapy delivered in a highly ...
Douglas Emily M - - 2013
Annually, 1,000-2,000 child welfare workers experience the death of a child client. The child welfare field has paid increasing attention to the impact of workplace trauma events on the psychological distress of child welfare workers. In this article the author assesses the relationship between experiencing a maltreatment fatality and workers' ...
Hundalani Shilpa - - 2013
Invasive fungal infections due to Candida are the third most common late-onset infection in infants born with birth weight <1500 g. Invasive candidiasis in infants born with birth weight <1000 g is associated with a 30% mortality and with neurodevelopmental impairment in more than half the survivors. A high degree of suspicion ...
Lee Jacob - - 2013
Falls and their associated injuries profoundly impact health outcomes, functional independence, and health care expenses, particularly for the ever-increasing elderly population. This systematic search and review assessed the current evidence for the role of fall screening assessments. To review the current evidence for fall risk screening assessments in community-dwelling (outpatient), ...
Cruz Ernesto - - 2013
Phantom limb pain is a frequent sequela of amputation. A high prevalence of residual limb pain and back pain also exists among amputees. We present a case of a new-onset severe phantom limb pain resulting from a metastatic spinal mass in an 81-year-old patient with a history of malignant sarcoma ...
Habib Rima R - - 2013
This research evaluated the association between women's self-rated health and a number of socioeconomic and environmental health indicators relating to drinking water services in an underserved Lebanese community. A population-based, cross-sectional survey using interviews was adopted to obtain information from female homemakers of 2,223 households in the town of Bebnine, ...
Sanford Cynthia A - - 2013
As hospitals and healthcare have become specialized, so has nursing. Orthopaedic nurse certification is an example of this specialization. The purpose of this article is to describe the outcomes of one specialty hospital's implemented plan designed to encourage and support nurses seeking to demonstrate expertise in orthopaedic nursing practice. A ...
Bauer Michael - - 2013
Abstract Objectives. This 2013 update of the practice guidelines for the biological treatment of unipolar depressive disorders was developed by an international Task Force of the World Federation of Societies of Biological Psychiatry (WFSBP). The goal has been to systematically review all available evidence pertaining to the treatment of unipolar ...
Roberts Dottie - - 2013
: The Orthopaedic Nurses Certification Board (ONCB) conducts a role delineation study (RDS) every 5 years. Results identify tasks performed by orthopaedic registered nurses, nurse practitioners, and clinical nurse specialists, and musculoskeletal health conditions commonly seen by patients under their care. The purpose of the study was to define current ...
Monczewski Lisa - - 2013
Bone is the third most common site of cancer metastasis resulting in pain and other serious morbidities that can affect one's quality of life. The orthopaedic patient with bone metastasis faces many challenges and has complex nursing care needs. Managing care involves astute assessment skills, knowledge of treatments including medication, ...
Unver Bayram - - 2013
Although studies determinate that the tourniquet and high tourniquet pressure applications lead to several complications and decelerate the rehabilitation, there was not any study investigating the effects of tourniquet pressure on rehabilitation outcomes and postoperative complications. To investigate the effects of the minimal and conventional tourniquet inflation pressures application on ...
McFadden Brenda - - 2013
The population of patients receiving posterior total hip arthroplasty (THA) is growing among middle-aged adults. Through literature review and a survey of colleagues, it has been presented that patients and medical staff tend not to discuss the effects of sexual activity on posterior THA. So the question arises, is the ...
Chesson Ralph - - 2013
Vaginal surgery is the true minimally invasive surgery in the treatment of pelvic organ prolapse (POP); however, the robotic industry and decreased resident training in vaginal surgery may result in the loss of skills among our graduates. There are a number of procedures that are well accepted in the management ...
Kutscher Beth - - 2013
Tenet Healthcare Corp.'s acquisition of Vanguard Health Systems is a sign the investor-owned chain is willing to take a chance on alternative payment models such as accountable care organizations. There's no certainty that ACOs will deliver the improvements on quality or cost savings, but Vanguard Vice Chairman Keith Pitts, left, ...
Rupp Michael - - 2013
Postoperative patients have higher incidences of respiratory complications. Patients undergoing abdominal or thoracic surgical procedures are at greater risk of having such complications. Incentive spirometry is an inhalation-based prophylactic technique that encourages patients to mimic a natural deep sigh to periodically increase lung volume. As this technique is the prophylactic ...
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