Search Results
Results 451 - 500 of 1287
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Choi Myung Jin - - 2013
Valvular calcification is associated with significant morbidity and mortality in patients with end stage renal disease (ESRD). This study examined the hypothesis that valvular calcification is a marker of myocardial ischemia in asymptomatic high-risk patients with ESRD. Echocardiography and myocardial perfusion single-photon emission computed tomography were performed in 285 asymptomatic ...
Peel Michael - - 2013
Cyclophilins (Cyps) are ubiquitous proteins that effect the cis-trans isomerization of Pro amide bonds, and are thus crucial to protein folding. CypA is the most prevalent of the ∼19 human Cyps, and plays a crucial role in viral infectivity, most notably for HIV-1 and HCV. Cyclophilins have been shown to ...
Raschenberger Julia - - 2013
Short telomere length has been described to be associated with biological aging including atherosclerosis phenotypes. However, information in patients with symptomatic peripheral arterial disease (PAD) is sparse. We therefore aimed to investigate whether inter-individual differences in relative telomere length (RTL) are associated with symptomatic PAD. We measured RTL by a ...
Giannerini Massimo - - 2013
Catalytic carbon-carbon bond formation based on cross-coupling reactions plays a central role in the production of natural products, pharmaceuticals, agrochemicals and organic materials. Coupling reactions of a variety of organometallic reagents and organic halides have changed the face of modern synthetic chemistry. However, the high reactivity and poor selectivity of ...
Kurashige Yuki - - 2013
It is a long-standing goal to understand the reaction mechanisms of catalytic metalloenzymes at an entangled many-electron level, but this is hampered by the exponential complexity of quantum mechanics. Here, by exploiting the special structure of physical quantum states and using the density matrix renormalization group, we compute near-exact many-electron ...
Wang Jing J Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, - - 2013
Mast cells (MCs) contribute to atherogenesis by releasing pro-inflammatory mediators to activate vascular cells and other inflammatory cells. This study examined whether MC activation or stabilization affects diet-induced atherosclerosis in low-density lipoprotein receptor-deficient (Ldlr(-/-)) mice. When Ldlr(-/-) mice consumed an atherogenic diet for 3 or 6 months, MC activation with ...
Kark Jeremy D - - 2013
Shorter leukocyte telomere length (LTL) is associated with higher incidence of coronary heart disease (CHD) and increased mortality. We examined the association of LTL with coronary artery calcification (CAC), which reflects the cumulative burden of coronary atherosclerosis, in an urban Arab sample of Palestinians, a population at high risk of ...
Idei Naomi - - 2013
It is clinically important to estimate the degree of endothelial dysfunction. Several methods have been used to assess endothelial function in humans. Recently, we developed a new noninvasive method for measurement of vascular response to reactive hyperemia in the brachial artery, named enclosed zone flow-mediated vasodilation (ezFMD). The purpose of ...
Andreozzi F - - 2013
Carotid Intima-Media Thickness (C-IMT) is a reliable predictor of cardiovascular events. We examined if increased C-IMT was associated with defects in glucose metabolism in non-diabetic subjects independently of age. In 366 Caucasian non-diabetic subjects of the CARAMERIS study, we measured glucose response during a 75 g-Oral Glucose Tolerance Test (OGTT), insulin ...
Persoon Ilona F - - 2013
Previous research showed an antimicrobial effect of vanadium chloroperoxidase (VCPO) on in vitro Enterococcus faecalis biofilms. The current study aimed to optimize the use of this enzyme at the root canal pH using a modified VCPO (mVCPO) that was adapted to function at a higher pH and to explore the biocompatibility ...
Siqueira José F JF - - 2013
This ex vivo study evaluated the disinfecting and shaping ability of 3 protocols used in the preparation of mesial root canals of mandibular molars by means of correlative bacteriologic and micro-computed tomographic (μμCT) analysis. The mesial canals of extracted mandibular molars were contaminated with Enterococcus faecalis for 30 days and assigned ...
Farnier Michel - - 2013
Apolipoprotein (apo) B is highly predictive of coronary risk, especially in patients with high triglycerides (TG). This post hoc analysis evaluated the effects of lipid-lowering therapy on correlations between apoB and low-density lipoprotein cholesterol (apoB:LDL-C) and non-high-density lipoprotein cholesterol (apoB:non-HDL-C) in patients with TG< and ≥200 mg/dL. This analysis used data ...
Ohno Shuji - - 2013
11β-hydroxysteroid dehydrogenase (HSD11B) catalyzes the interconversion between active and inactive glucocorticoid, and is known to exist as two distinct isozymes: HSD11B1 and HSD11B2. A third HSD11B isozyme, HSD11B1L (SCDR10b), has recently been identified. Human HSD11B1L, which was characterized as a unidirectional NADP(+)-dependent cortisol dehydrogenase, appears to be specifically expressed in ...
Braicu Cornelia - - 2013
p53 protein is probably the best known tumor suppressor. Earlier reports proved that human breast cancer cells expressing mutant p53 displayed resistance to apoptosis. This study is intended to investigate, the potential applications of RNA interference (RNAi) to block p53 expression, as well as its subsequent effect on cell growth, ...
Turgeon Julie - - 2013
Fish oil consumption has been associated with a reduced incidence of cardiovascular diseases. However, the precise mechanisms involved are not completely understood. Here we tested the hypothesis that a fish oil-enriched diet improves neovascularization in response to ischemia. C57Bl/6 mice were fed a diet containing either 20% fish oil, rich ...
Wu Jiakai - - 2013
Maternal smoking increases the risk of respiratory symptoms in children. Glutathione S-transferases (GSTs) detoxify xenobiotics from tobacco smoke, and functional polymorphism in GST gene(s) could predispose children to the detrimental effects of maternal smoking. Our objective was to investigate interactions between GST variants and maternal smoking in relation to the ...
Dejter Sandra - - 2013
The treatment of breast cancer generates changes to the body and a person's self-image. The caregivers' support focuses on the woman's grief for her old body and the acceptance of a changed intimacy. Listening to each woman is essential for acknowledging her fears in the face of this mutated body, ...
Ouyang Dian - - 2013
Laryngeal reconstruction is needed to preserve laryngeal function in patients who have undergone extensive vertical or frontal partial laryngectomy. However, the procedure remains a difficult challenge. Several reconstruction techniques have been described, but these techniques pose risks of complications such as laryngeal stenosis. This study aimed to evaluate the postoperative ...
Venkatesan Amouda - - 2013
To predict the structure of protein, which dictates the function it performs, a newly designed algorithm is developed which blends the concept of self-organization and the genetic algorithm. Among many other approaches, genetic algorithm is found to be a promising cooperative computational method to solve protein structure prediction in a ...
Borycki Elizabeth - - 2013
Health information technology (HIT) research findings suggested that new healthcare technologies could reduce some types of medical errors while at the same time introducing classes of medical errors (i.e., technology-induced errors). Technology-induced errors have their origins in HIT, and/or HIT contribute to their occurrence. The objective of this paper is ...
Bai Bing - - 2013
This study aims to investigate the clinicopathologic significance of lymphatic vessel invasion (LVI) labeled by D2-40 monoclonal antibody in esophageal squamous cell carcinoma (ESCC). Immunohistochemical assay was used to detect the expression of D2-40 and LVI in 107 ESCC patients. Then, the correlation between the clinicopathologic feature and the overall ...
Akyuz Aydın - - 2013
Spontaneous coronary artery dissection (SCAD) and woven coronary artery anomaly (WCAA) are relatively rare. A few of the previously reported woven coronary artery cases have involved in a single coronary artery. We present an unusual woven case involving all coronary arteries and two patient with SCAD. We have also reviewed ...
Pfeil-Thiriet Francine - - 2013
In France, one woman in eight is treated for breast cancer before the age of 75. The 2009-2013 cancer plan recommends providing support for women after cancer. A therapeutic education programme helps them reintegrate into their daily life.
Lee Sang Yun - - 2013
The Gerbode shunt, known as the left ventricle to the right atrial communication, is a rather rare finding, following surgical closure of septal defects. Even though the surgical closure is accepted as a treatment of choice, we report a successful percutaneous transcatheter closure of the Gerbode shunt in a 3-months ...
Choudhary Sonal - - 2013
Drug rash with eosinophilia and systemic symptoms syndrome is a severe idiosyncratic drug reaction with a long latency period. It has been described using many terms; however, drug rash with eosinophilia and systemic symptoms syndrome appears to be the most appropriate. This syndrome causes a diverse array of clinical symptoms, ...
Nery Mariana F - - 2013
Cetaceans, early in their evolutionary history, had developed many physiological adaptations to secondarily return to the sea. Among these adaptations, changes in molecules that transport oxygen and that ultimately support large periods of acute tissue hypoxia probably represent one big step toward the conquest of aquatic environments. Myoglobin contributes to ...
Gommier-Lefort Valérie - - 2013
In the Centre region of France, breast cancer is one of the three most common and most fatal forms of the disease. Chartres hospitals offer complete care provision on a single site and assess the time taken for the appropriate care to be put in place. The nurse coordinator plays ...
Choi Wona - - 2013
Intensified competitiveness in the healthcare industry has increased the number of healthcare centers and propelled the introduction of customer relationship management (CRM) systems to meet diverse customer demands. This study aimed to develop the information system success model of the CRM system by investigating previously proposed indicators within the model. ...
Ercan Suleyman - - 2013
Brugada syndrome is a life threatening disease that is usually overlooked during emergency service admissions. It is characterized by typical electrocardiography resembling right bundle branch block, static or dynamic ST-segment elevation in leads V 1-3. There is familial tendency in some cases. A majority of patients have a structurally normal ...
Cohen Philip R PR The University of Houston Health Center, University of Houston, Houston, Texas; The Division of Dermatology, University of California San Diego, San Diego, California ; The Department of Dermatology, The University of Texas M.D. Anderson Cancer Center, Houston, Texas ; The Department of Dermatology, University of Texas-Houston Medical School, Houston, - - 2013
Syringoma of the penis is rare. This paper describes two men with syringoma of the penis and summarizes the clinical features of previously reported men with this condition. A 25-year-old African man presented with a nonpruritic flesh-colored papule on the right side of his proximal dorsal penile shaft and a ...
Dorit Robert L RL Department of Biological Science, Smith College, Northampton, MA, 01063, - - 2013
The rise of antibiotic-resistant pathogens focuses our attention on the source of antibiotic resistance genes, on the existence of these genes in environments exposed to little or no antibiotics, and on the relationship between resistance genes found in the clinic and those encountered in non-clinical settings. Here, we address the ...
Regan Jamie J Unilever Global Skin Claims, Trumbull, - - 2013
To assess the properties of a novel body wash containing the mild surfactant glycinate. Biochemical and clinical assays. Research laboratories and clinical sites in the United States and Canada. Women 18 to 65 years of age (cleansing efficacy); male and female subjects 26 to 63 years of age with mild ...
Cui Wei - - 2013
Non-parasitic hepatic cysts with biliary communication are rare. The clinical symptoms involved are not specific to this condition, thereby making diagnosis difficult and treatment controversial. Here, we report a case of 70-year-old woman complaining of abdominal satiety, combined with non-specific pain in the right upper quadrant. The abdominal contrast-enhanced MRI-scan ...
Wintz Lydie - - 2013
Around 20 to 30% of women treated for breast cancer undergo a mastectomy in France. Of these patients, 70% do not have reconstructive surgery. It would seem that information surrounding reconstructive procedures is insufficient. Tools created in partnership with caregivers and patients are necessary to help women understand the choices ...
Taylor Jennifer - - 2013
There is no increase in life expectancy for vegetarians and the jury is out on the protective effects of fish
Bae Myung Hwan - - 2013
Rapid diagnosis of ST-segment elevation myocardial infarction (STEMI) is essential for the appropriate management of patients. We investigated the prevalence, etiologies and predictors of false-positive diagnosis of STEMI and subsequent inappropriate catheterization laboratory activation in patients with presumptive diagnosis of STEMI. Four hundred fifty-five consecutive patients (62±13 years, 345 males) ...
Yuan Yuan - - 2013
Screening and early diagnosis of gastric cancer play important roles in reducing the mortality of gastric cancer. A vast amount of study data on gastric cancer screening and early diagnosis has been accumulated in and out of China in the past decades. The practice of gastric cancer screening has also ...
Espié Marc - - 2013
A major public health issue, breast cancer affects 53000 women each year in France. The leading cause of cancer deaths in women, its risk factors are numerous and include age, early puberty and/or late menopause, later age at first pregnancy as well as a family history of the disease.
Tofield Andros - - 2013
Exposure to air pollution is associated with increased mortality after myocardial infarction
Jeong Dong Seop - - 2013
Atrial fibrillation (AF) is the most common chronic arrhythmia in the world, and it is associated with an increased long-term risk of stroke, heart failure, and all-cause mortality. To overcome the limitations of transvenous radiofrequency (RF) ablation for AF, total thoracoscopic ablation (TTA) has evolved as a new technique. TTA ...
Peikari Hamid Reza - - 2013
Some hospitals have implemented computerized physician order entry (CPOE) systems to reduce the medical error rates. However, research in this area has been very limited, especially regarding the impact of CPOE use on the reduction of prescribing errors. Moreover, the past studies have dealt with the overall impact of CPOE ...
Gast Karin B - - 2013
The relative importance of insulin resistance and hyperglycemia to the development of atherosclerosis remains unclear. Furthermore, adiposity may be responsible for observed associations. Our aim was to study the relative contributions of adiposity, insulin resistance and hyperglycemia to subclinical atherosclerosis. In this cross-sectional analysis of the Netherlands Epidemiology of Obesity ...
Wang Yi-Hao - - 2013
A 60-year-old woman with squamous cell carcinoma in the right lung was successfully treated with four cycles of combination chemotherapy after surgery, and complete remission was achieved. However, the patient developed myelodysplastic syndrome (MDS) RAEB-2 with myelofibrosis after remission, possibly because of chemotherapy or DNA methylation. The patient responded well ...
Kim Yoo Ri - - 2013
Familial hypercholesterolemia (FH) is associated with premature atherosclerotic cardiovascular diseases, and is inherited as an autosomal dominant trait. The prevalence of heterozygous FH is one in five hundred people. Owing to dysfunctional low density lipoprotein (LDL) receptors due to genetic mutations, serum low density lipoprotein-cholesterol (LDL-C) levels are considerably increased ...
Hong Man Yong - - 2013
Coronary artery anomalies are rare presentations in primary percutaneous coronary interventions of acute myocardial infarction. Herein, we report the case of a 59-year-old man with acute anterior myocardial infarction who had anomalous separate origin of left anterior descending artery (LAD) and left circumflex artery (LCX) from the left coronary aortic ...
Barbier Elisabeth - - 2013
Hypnosis is a non-medication based approach used increasingly in hospitals. In oncology, practised by a trained nurse hypnotherapist, it represents a complementary medicine.
Dariel Odessa - - 2013
Q-Methodology offers an alternative to traditional methodological approaches. It is similar to qualitative methods while at the same time guaranteeing a statistical data analysis. It can be particularly interesting for the development of nursing sciences.
Duan Xiao-Feng - - 2013
Splenic metastasis is generally not a common clinical event. However, metastasis to the spleen from adrenal pheochromocytoma is extremely rare and has not been reported in literature. This report presents a case of a 58 year-old male patient who developed spleen-only metastases in July 2007. The patient had a previous ...
De Pauw Antoine - - 2013
Screening for breast cancer should concern all women at some point in their life. In cases of a family history of breast cancer, an oncogenetic consultation may be offered. The identification of a genetic predisposition enables specific management strategies for the woman to be drawn up.
- - 2013
ESC is to create an inventory of cardiovascular disease registries and a task force on data standardization
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