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Results 401 - 450 of 1237
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Van Nieuwenhuysen Els - - 2013
Nonepithelial ovarian cancers (OCs), including sex cord-stromal tumors (SCSTs) and germ cell tumors (GCTs), are an uncommon subset of OC, together accounting for 10% of all OCs. The etiology of these tumors remains largely unresolved. It is well established that tumorigenesis is the result of multiple genetic alterations driving a ...
Yu Xinfang - - 2013
Programmed cell death plays an important role in animal development, tissue homeostasis and eliminating harmful or virally infected cells. Necroptosis, a novel form of programmed cell death, is caspase independent but RIPK and RIPK3 dependent. Moreover, it is suggested that necroptosis can be specifically inhibited by small molecular inhibitors such ...
Hsieh Ya-Lun - - 2013
Abstract This study was undertaken to determine whether there was an association between fine particles (PM2.5) levels and hospital admissions for congestive heart failure (CHF) in Taipei, Taiwan. Hospital admissions for CHF and ambient air pollution data for Taipei were obtained for the period 2006-2010. The relative risk of hospital ...
Murray Christian J - - 2013
Abstract Susceptible sub-populations with existing disease have exhibited stronger relationships between air quality and mortality in time-series studies, but their associated life expectancies have largely been overlooked. Murray and Nelson developed a new time-series model that estimated a small unobserved (frail) sub-population and their resulting life expectancies in Philadelphia, including ...
McClain Natalie - - 2013
It is unclear whether survivors of trauma are at risk of emotional or psychological distress when they participate in research because there is little data on the subjective experience of research study participants and how they make meaning from their participation in research. This qualitative descriptive study explored the experience ...
Jormfeldt Henrika - - 2013
Patient education in mental health care is a conventional intervention to increase patients' knowledge about their illness and treatment. A provider-centered focus in patient education may put patients in a passive role, which can counteract their processes of recovery. There is an increasing emphasis on recovery-oriented practice, an approach that ...
Shao Qi - - 2013
ABSTRACT. Tumor hypoxia is an important factor in assessment of both cancer progression and cancer treatment efficacy. This has driven a substantial effort toward development of imaging modalities that can directly measure oxygen distribution and therefore hypoxia in tissue. Although several approaches to measure hypoxia exist, direct measurement of tissue ...
Stanton Robert - - 2013
Objectives: There is growing evidence regarding the efficacy of exercise as a treatment strategy for patients with depression. This paper summarises the benefits of both cardiovascular and resistance exercise for patients with depression. Design: A narrative review design was employed. Supporting literature for the individual and combined benefits of both ...
Jones Nev - - 2013
Although the hearing voices movement (HVM) has yet to take root in the US to the extent it has in the UK (and parts of Australia and Europe), recent publications and events, including a keynote presentation by UK hearing voices trainer Ron Coleman at the 2012 Annual NAMI convention and ...
Thompson Mindi N - - 2013
The experiences of vicarious unemployment (VU) among 17 undergraduate student participants who had a primary caregiver who was involuntarily unemployed were explored using grounded theory (Charmaz, 2006; Glaser & Strauss, 1967). Data from semistructured interviews with 15 women and 2 men revealed the nuanced nature of experiences with unemployment among ...
Esteghamati A - - 2013
The aim of the current study was to evaluate the association of osteoprotegerin and vascular endothelial growth factor (VEGF) with glycemic indices and diabetes status. A total of 44 normoalbuminuric Type 1 diabetic patients and 44 healthy control subjects, matched for age, body mass index, sex ratio, and lipid measures ...
Malekinejad Hassan - - 2013
Abstract The protective effect of hydroalcoholic extract of hawthorn berries (HBE) on acetic acid (AA)-induced colitis in rats was investigated. Forty-two Wistar rats were divided into seven groups, including control and test groups (n=6). The control animals received saline, and the test animals were treated with saline (sham group), mesalamine ...
Alonso Eliana Noelia - - 2013
Abstract It is already known that the Maitake (D-Fraction) mushroom is involved in stimulating the immune system and activating certain cells that attack cancer, including macrophages, T-cells, and natural killer cells. According to the U.S. National Cancer Institute, polysaccharide complexes present in Maitake mushrooms appear to have significant anticancer activity. ...
Wiles Lynn L - - 2013
Newly graduated nurses (NGNs) are thrust into roles that some purport they are inadequately prepared to handle. This study investigated the experience of NGNs as they made clinical judgments in the critical care setting. Three themes emerged: developing confidence in practice, seeking assistance, and decision making. Nursing professional development educators ...
Wodrich Elizabeth - - 2013
Rural nurses are expected to be competent and confident caregivers for patients of all ages and disease states. Rural nurse educators are challenged with creating appropriate learning environments to assess and maintain nursing competencies in resource-limited areas. This project describes and evaluates the utilization of a simulation manikin from a ...
Wittmann-Price Ruth - - 2013
The professional development department members are instrumental in leading nursing research and quality improvement projects. Rarely do academic nurse researchers know the staff, culture, and capabilities of an organization like the members of the staff development department. Developing a collaborative program using the talents of the professional development department members ...
Munro Kimberly - - 2013
Objective: No official provisions are made for the medically uninsured under provincial public health programs in Canada. Studies have shown that uninsured pregnant women have inadequate access to prenatal and obstetrical services that favour healthy maternal and child outcomes. This qualitative study aimed to explore the perspectives of family physicians ...
Salmon David P - - 2013
Objective: This study examined the impact of age and apolipoprotein E (APOE) genotype on the rate of cognitive decline in nondemented elderly participants in a simulated Alzheimer's disease (AD) primary prevention treatment trial carried out by the Alzheimer's Disease Cooperative Study. Method: Cognitive tests were administered at baseline and at ...
Crane Joan M G - - 2013
Objective: To evaluate the effects of extreme obesity (pre-pregnancy BMI ≥ 50.0 kg/m2) in pregnancy on maternal and perinatal outcomes. Methods: We conducted a population-based cohort study using the Newfoundland and Labrador Perinatal Database to compare obstetric outcomes in women with extreme obesity and those with a normal BMI (pre-pregnancy ...
Sagynbekov Ken Imanak - - 2013
Objective: Studies of maternal mortality that use data from multiple countries often identify statistically significant correlates and interpret them as factors relevant to policy. This study was designed to address the fragility of a statistical association between the maternal mortality rate and its main correlates, and to assess the relevance ...
Mosavi-Jarrahi Alireza - - 2013
Objectives: To use the most recent data to update the trend in cervical cancer incidence in Canada over the 30 year period from 1978 to 2009. Methods: Registered cases of cervical cancer and the corresponding person years for the Canadian population were retrieved from an online data repository of the ...
Cattapan Alana - - 2013
In June 2012, the Canadian House of Commons passed the so-called omnibus budget bill, making several important changes to the governance of assisted reproduction in Canada. The bill (Bill C-38) was widely criticized for its unwieldy size and rapid passage through Parliament, preventing adequate parliamentary debate and public scrutiny. Given ...
Regier Dean A - - 2013
Objective: To examine colposcopists' attitudes regarding human papillomavirus (HPV) DNA testing as a primary screening tool for cervical cancer. Methods: Questionnaires administered in 2010 and 2011 during workshops in British Columbia elicited colposcopists' attitudes using a series of five-point Likert-style scales (strongly disagree to strongly agree) and binary (yes/no) response ...
Bestges B-B - - 2013
Background: Many people depend on additional help to maintain their daily needs. In these circumstances preventive medical check-ups are frequently not attended, so that disease development may remain undetected until advanced stages or correctable disorders may not be treated. A fully anonymised cross-sectional study was set up to assess feasibility ...
Pahlitzsch M - - 2013
Background: Poppers are a common drug belonging to the alkyl nitrite group and in use for several decades. They can be legally purchased for air freshening, but are illegal to buy for inhalation. Abuse is associated with maculopathy and visual loss as a rare side effect.Method: A case series of ...
Sasaki Motoharu - - 2013
At present, every manufacturer of intensity modulated radiation therapy (IMRT) equipment uses multi-leaf collimators (MLCs); however, each company's intensity modulation methods and dose calculation algorithms differ. This study used four typical radiation treatment planning systems (RTPSs) employed domestically for prostate IMRT plans to carry out 15 case studies by one ...
Yokohama Noriya - - 2013
This report was aimed at structuring the design of architectures and studying performance measurement of a parallel computing environment using a Monte Carlo simulation for particle therapy using a high performance computing (HPC) instance within a public cloud-computing infrastructure. Performance measurements showed an approximately 28 times faster speed than seen ...
Daragó László - - 2013
Telemedicine is used more and more frequently worldwide. It is increasingly popular in North America, Australia, South Africa, as well as the Scandinavian countries. However, it is not commonly used in Hungary despite various attempts, which is presumably due to earlier dismissive governmental attitude. In this paper the authors analyze ...
Szeverényi Csenge - - 2013
Recently, various ways of carrying a baby have become popular again. Different methods and options of infant carrying are largely influenced by current fashion trends. The term of baby carrying refers to carrying the infant close to the caregiver's body with special devices, which aid attachment parenting. The authors often ...
Kleiner Dénes - - 2013
Introduction: Transmethylation modifies configuration and proceeds via formaldehyde. It has a significant role for example in epigenetic regulation. The whole methyl-pool can be evaluated by the measurement of bound formaldehyde. Aim: The bound formaldehyde was measured in wheat, bean, beetroot, cabbage, broiler- and rabbit liver. The relationship between transmethylation and ...
Gulácsi László - - 2013
Introduction:C. difficile causes 25 percent of the antibiotic associated infectious nosocomial diarrhoeas. C. difficile infection is a high-priority problem of public health in each country. The available literature of C. difficile infection's epidemiology and disease burden is limited. Aim: Review of the epidemiology, including seasonality and the risk of recurrences, ...
Yang Li-Yu - - 2013
Kyphoplasty reduces the pain caused by osteoporotic vertebral compression fracture (OVCF). Although the procedure is typically carried out using a bilateral approach, it is now increasingly performed using a unilateral approach because of the concern for long-term adverse effects. However, little evidence is available to demonstrate superior safety of the ...
Kaya Serap - - 2013
Chronic pelvic pain (CPP) is a complex pain syndrome. Since its pathogenesis is still poorly understood and structural alterations in pain related brain regions may be present, there is a greater acceptance that sensitization of the central nervous system (CNS) plays an important role in the development and maintenance of ...
Chandra Ronil V - - 2013
Although over 300 articles have been published annually on vertebral augmentation in the last 5 years, there remains much debate about a fundamental question - is vertebral augmentation a safe and effective treatment to achieve analgesia, reduce disability, and improve quality of life in patients with a vertebral fracture? In ...
Atluri Sairam - - 2013
Transforaminal technique for epidural steroid injections, unlike other approaches, is uniquely associated with permanent, bilateral, lower extremity paralysis. To review the literature and analyze the reported cases of paralysis from lumbar transforaminal epidural steroid injections to possibly establish a cause and to prevent this complication. Eighteen cases of paralysis from ...
Park Chan Hong - - 2013
Cervical central stenosis (CCS) is a narrowing of the spinal canal that can cause mechanical compression of the spinal nerve and roots, leading to neck pain and/or radicular pain. Cervical epidural steroid injections are commonly used in the treatment of CCS. After failure of epidural steroid injections, the next sequential ...
Kim Hyeun Sun - - 2013
Percutaneous endoscopic lumbar discectomy is a common surgical treatment for lumbar disc herniation, and percutaneous endoscopic interlaminar lumbar discectomy (PEID) is commonly used for direct decompression of L5-S1. Like microdiscectomy, recurrence of herniation after endoscopic discectomy is an important problem. In this study, we aimed to decrease the recurrence after ...
Timpone Vincent M - - 2013
The utilization of spinal interventional pain techniques has grown rapidly over the last decade. However, practitioners use widely different techniques in these procedures, particularly in the use of image guidance. The importance of image guidance was highlighted by the fact that in recent systematic reviews on therapeutic effectiveness of epidural ...
Te Boveldt Nienke - - 2013
Pain prevalence at various stages of cancer ranges from 27% to 60% for outpatients. Yet, how pain is managed in this patient group is poorly understood. The primary objective was to assess pain prevalence and intensity, and its interference with daily activities, in medical oncology outpatients. The secondary objectives were ...
Pennekamp Werner - - 2013
Lumbar sympathetic blocks and chemical sympathectomies are used for the pain treatment of peripheral arterial occlusive disease or sympathetically maintained pain syndrome after nerve injury or complex regional pain syndrome (CRPS). A 30-year-old patient was referred to the pain department with all the clinical signs and symptoms of a CRPS ...
Wolter Tilman - - 2013
Despite the good clinical results elicited by spinal cord stimulation (SCS), the physiological basis of action of SCS is widely unknown. Inhibition of somatosensory evoked potential (SEP) amplitudes by SCS has been described, but it is unclear whether this displays dose dependency. Moreover, it is unknown whether the pain-relieving effect ...
Manchikanti Laxmaiah - - 2013
Both the Office of Inspector General (OIG) and reports from studies of the utilization of facet joint interventions have expressed that explosive increases in facet joint interventions provided to spinal pain patients are a major concern. The study is designed to assess the growth of facet joint interventions in managing ...
Manchikanti Laxmaiah - - 2013
  The high prevalence of persistent low back pain and growing number of diagnostic and therapeutic modalities employed to manage chronic low back pain and the subsequent impact on society and the economy continue to hold sway over health care policy. Among the multiple causes responsible for chronic low back ...
Saxena Akriti P - - 2013
Vertebral augmentation (VA) techniques have changed the paradigm of treatment during the past decade and involve injection of polymethylmethacrylate (PMMA) cement directly into a compressed vertebral body. During the summer of 2009, the INVEST trial was one of 2 randomized controlled studies that reported equivalence between vertebroplasty and a control ...
Anselmetti Giovanni Carlo - - 2013
Vertebral metastases are associated with significant pain, disability, and morbidity. Open surgery for fracture stabilization is often inappropriate in this cancer population due to a poor risk-benefit profile, particularly if life expectancy is short. Vertebroplasty and kyphoplasty are appealing adjunctive procedures in patients with malignancy for alleviation of intractable pain. ...
Woo Jae Hee - - 2013
Radicular pain has been considered to be a relative contraindication to vertebroplasty. It was reported by some authors in the literature that percutaneous vertebroplasty (PV) in these conditions were performed without complications. We describe a patient with radicular pain related to compression of the dorsal root ganglion by malignant tumor ...
Wang Yang - - 2013
Vertebroplasty (VP) and kyphoplasty (KP) are emerging procedures for almost immediate pain relief when treating osteoporotic or osteolytic fractures. The main reported complication is polymethylmethacrylate (PMMA) leakage, which may lead to compression of neural structures or embolism. Different authors have proposed that intravertebral pressure (IP) is an important factor determining ...
Jian Wang - - 2013
Vertebral hemangioma (VH) is considered to be a benign lesion of bone with a rich vasculature. Most incidentally discovered hemangiomas are asymptomatic. Percutaneous vertebroplasty (PVP) has demonstrated efficacy in the treatment of symptomatic thoracic and lumbar VHs. To our knowledge, the reports concerning PVP on symptomatic cervical VHs are quite ...
Sun Gang - - 2013
The clinical management of osteolytic metastases involving C2 is unique, because it is challenging to approach these lesions. Symptoms may vary from local pain to progressive neurological deficit. Surgery or radiotherapy have been the treatments of choice for several years; however, surgery may not bean option for patients with multiple ...
Fukui Sei - - 2013
Discogenic pain is an important cause of low back pain (LBP). We have developed a pulsed radiofrequency (PRF) technique, using Diskit II® needles (NeuroTherm, Middleton, MA, USA) placed centrally in the disk, for applying radiofrequency current in the disc (Intradiscal PRF method). The purpose of this study was to investigate ...
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