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Results 351 - 400 of 1237
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Tack Jan - - 2013
Current interventions for irritable bowel syndrome with constipation tend to target single symptoms of the disorder, with multiple symptom relief only achieved through the use of combinations of therapies. Hence, there remains an unmet need for well-tolerated and effective treatments for irritable bowel syndrome with constipation that target abdominal symptoms, ...
Zhao Liang - - 2013
Circumferential pulmonary vein isolation (CPVI), as the basal ablation strategy for treating atrial fibrillation (AF), not only isolates the connection between the left atrium (LA) and the pulmonary veins (PVs), but also induces extensive atrial endocardia damage. This could have an effect on the sinus pulse conduction in the LA ...
Feng Xiang-Fei - - 2013
Pulmonary vein antrum isolation (PVAI) of pre-excited atrial fibrillation (AF) is controversial. This study aimed to observe the therapeutic effects of PVAI on pre-excited AF. Twenty-nine patients with pre-excited AF were prospectively divided into a PVAI group (group I, 19 cases) and a control group (group II, 10 cases). To ...
Wang Na - - 2013
Chronic heart failure (CHF) is a severe clinical syndrome associated with high morbidity and mortality, and with high health care expenditures. No nationwide data are currently available regarding the quality of clinical management of CHF patients in China. The aim of this study was to assess the quality of care ...
Nie Xiao-Min - - 2013
Stent thrombosis is one of severe complications after sirolimus-eluting stent implantation. Rapamycin (sirolimus) promotes arterial thrombosis in in vivo studies. However, the underlying molecular and transcriptional mechanisms of this adverse effect have not been thoroughly investigated. This study was designed to examine the effects of rapamycin on the expression of ...
Xiao Li - - 2013
The human leukocyte antigen-G (HLA-G) has been considered to be an important tolerogeneic molecule playing an essential role in maternal-fetal tolerance, upregulated in the context of transplantation, malignancy, and inflammation, and has been correlated with various clinical outcomes. The aim of this study was to investigate the clinical relevance of ...
Chen Shan-Lin - - 2013
Schwannomatosis is a recently recognized peripheral nerve polyneoplasm with clinical characteristics and a genetic background that differ from those of neurofibromatosis 2 (NF2). The diagnostic and treatment criteria of this rare disorder are herein discussed. The data of 180 patients who underwent operations for benign schwannomas from 2003 to 2012 ...
Ren Wei-Hong - - 2013
Patients with maxillary tumor often suffer from trismus after maxillectomy, which could turn out to be a permanent sequela without proper intervention. In this study, the efficacy of mouth opening exercises in preventing and treating trismus was observed in patients with maxillary tumor early after their operations. At the same ...
Wu Jing - - 2013
Vancomycin-resistant Enterococci (VRE) cause serious infections that are difficult to treat. We carried out this study to determine the mutant prevention concentration (MPC) of linezolid when combined with minocycline against VRE strains, to determine the mechanism of drug resistance in vitro, and to provide a theoretical basis for the rational ...
Gao Shuo-Hui - - 2013
Colon cancer is one of the major malignancies worldwide and it still remains resistant to much of the currently available chemotherapy. Downregulation of HGF/c-Met signaling pathway is an emerging therapy for cancer treatment. In this study, the inhibitory effects of c-Met phosphorylation were observed with SU11274 on different colon cancer ...
Fan Jian-Xia - - 2013
The importance of diagnosis of thyroid dysfunction during pregnancy has been widely recognized. Our study was designed to compare two different detection reagents between Abbott and Roche and to establish the gestationalrelated reference intervals for thyroid function tests (TFT) in Chinese women and to assay the reference ranges with the ...
Essawy S S - - 2013
Inhibition of xanthine oxidase by allopurinol increases hypoxanthine and xanthine, which are converted to purines, including the inhibitory neuromodulator adenosine. We aimed to investigate the antinociceptive effects of allopurinol in thermal and chemical pain models in mice and to evaluate its possible antinociceptive mechanism by using selective adenosine receptors A1, ...
Evsen M S - - 2013
The aim of this study was to investigate the antioxidative effects of estradiol (E), E plus progesteron (P) combination (E/P) and genistein (G) treatment in the brain of ovariectomized (OVX) rats. Adult female Sprague-Dawley rats were divided into five groups, with each group including ten rats. Rats were anesthetized and ...
Ebrahimzadeh M A - - 2013
Juglans (J.) regia L. is known to possess many biological properties. In this study, antihemolytic activity of methanol extract of Juglans regia L. flower were investigated. Antihemolytic activities of Juglans regia L. flowers were evaluated by various in vitro assays. In addition, scavenging of hydrogen peroxide and mineral contents of ...
Ying B - - 2013
With the idea of "replacing lost tissure with similar tissure in kind", vessel-pedicled palate mucosal flap, pedicled buccal musculomucosal flap and adjacent tongue musculomucosal flap could be the ideal approaches to soft palate reconstruction. To assess the adjacent tongue musculomucosal flap for soft palate reconstruction. From August 2010 to July ...
Gulhas N - - 2013
We aimed to compare the effect of remifentanil without muscle relaxant with succinylcholine for intubation in microlaryngoscopy. Eighty patients were randomly divided into two groups: Group R (n=40) and S (n=40) received remifentanil 4 µg/kg intravenously or 1 µg/kg respectively. Anesthesia was induced with 2 mg/kg propofol in both groups. ...
Freedman Stephen B - - 2013
Acute gastroenteritis (AGE) is an extremely common paediatric condition, which results in significant morbidity in children and is a financial burden to the society. The purpose of this overview is to critically evaluate the evidence currently available in the Cochrane Database of Systematic Reviews (CDSR) regarding the efficacy and safety ...
Coren Esther - - 2013
Numbers of street-connected children and young people run into many millions worldwide and include children and young people who live or work in street environments. Whether or not they remain connected to their families of origin, and despite many strengths and resiliencies, they are vulnerable to a range of risks ...
Choo Karen Jui Lin - - 2013
Anaphylaxis is a serious hypersensitivity reaction that is rapid in onset and may result in death. Anaphylaxis guidelines recommend glucocorticoids for the treatment of people experiencing anaphylaxis.  We sought to assess the benefits and harms of glucocorticoid treatment during episodes of anaphylaxis. In our previous version we searched the literature ...
Sabhaney Vikram - - 2013
These are commentaries on a Cochrane review, published in this issue of EBCH, first published as: Schuetz P, Müller B, Christ-Crain M, Stolz D, Tamm M, Bouadma L, Luyt CE, Wolff M, Chastre J, Tubach F, Kristoffersen KB, Burkhardt O, Welte T, Schroeder S, Nobre V, Wei L, Bhatnagar N, ...
Schuetz Philipp - - 2013
Acute respiratory infections (ARIs) comprise a large and heterogeneous group of infections including bacterial, viral and other aetiologies. In recent years, procalcitonin - the prohormone of calcitonin - has emerged as a promising marker for the diagnosis of bacterial infections and for improving decisions about antibiotic therapy. Several randomised controlled ...
Prabhakar Hemanshu - - 2013
Failure to respond to antiepileptic drugs in uncontrolled seizure activity such as refractory status epilepticus (RSE) has led to the use of anaesthetic drugs. Coma is induced with anaesthetic drugs to achieve complete control of seizure activity. Thiopental sodium and propofol are popularly used for this purpose. Both agents have ...
Banfi Cristina - - 2013
Proteomics is the study of the "proteome", that is the entire protein complement of a genome. However, it is well recognized that the proteome is far more complex than previously suggested by the "one-gene, one-protein" central dogma of biology. The proteome encompasses all proteins of a cell or organism at ...
Anzini Marco - - 2013
Although the cause of myocarditis often remains unknown, a large variety of infections, systemic diseases, drugs and toxins have been associated with this disease. In most cases, myocarditis is induced by cardiotropic viruses and often evolves silently without discernible prognostic impact. However, in some patients, the lack of complete viral ...
Marsico Fabio - - 2013
Systemic inflammatory diseases are associated with increased cardiovascular morbidity and mortality. The link between inflammatory and cardiovascular diseases can be attributed to the coexistence of classical risk factors and inflammatory mechanisms activated during systemic inflammatory diseases involving the immune system. Unfavorable metabolic effects of anti-inflammatory drugs can also contribute to ...
Pizzi Carmine - - 2013
Patients with acute or chronic ischemic heart disease have a high incidence of depression, and a variable proportion of patients (ranging from 14% to 47%) suffer from major or subclinical depression. In addition, chronic depression has been shown to be associated with the development or progression of coronary atherosclerosis. Besides ...
Di Eusanio Marco - - 2013
Aortic disease is the most life-threatening complication of Marfan syndrome. Over the last decades, improved medical management and surgical results of prophylactic aortic interventions on the aortic root have dramatically increased expectancy of life in Marfan syndrome patients. As a result, the number of Marfan syndrome patients requiring secondary interventions ...
Grego Susanna - - 2013
Background. The diagnosis and surgical treatment of patients with Marfan syndrome remain controversial. It is of utmost importance to identify patients at risk for acute aortic events to establish the correct surgical timing and the appropriate surgical treatment.Methods. From May 2008 to December 2012, 500 patients were screened at the ...
Tufaro Vincenzo - - 2013
We report the case of a 63-year-old woman admitted to the intensive care unit because of acute decompensated right heart failure. Transthoracic and transesophageal echocardiography revealed severe right ventricular dysfunction with severe tricuspid regurgitation of unknown origin and a large membrane running from the inferior vena cava to the interatrial ...
Consolver Patricia - - 2013
Realizing that data integrity and patient information accuracy are crucial to proper payment, Texas Health Resources reduced its duplicate patient records by 21 percent to achieve cleaner claims and faster cash flow. Here are five ways the 13-hospital system met this challenge.
Husty Todd M - - 2013
Healthcare organizations should address physician clinical documentation improvement now, before the Oct. 1, 2014, implementation deadline for ICD-10, if they are to mitigate risk related to ICD-10 and optimize operational processes. Improving documentation now will have an immediate effect on revenue and will minimize the potential for losses related to ...
Showalter J Stuart - - 2013
Action steps hospitals and health systems should take to prepare for a public relations (PR) crisis include the following: Develop a plan for dealing with PR crises that establishes a central incident command center and sets forth clear lines of authority and responsibility. Provide the name, phone number, email address, ...
Pizzo James J - - 2013
Numerous factors contribute to an organization's "risk tolerance" under performance-based risk arrangements, including its size, patient population, and the strength of its financial position. There are three types of risk inherent in value-based contracting: Financial risk. Actuarial risk. Strategic risk.
Wolfskill Sandra J - - 2013
Peer group comparisons can help revenue cycle leaders: Review their performance through an external lens. Set targets and motivate their teams. Provide informed answers to questions from the C-suite.
Berman Lani - - 2013
Gainsharing initiatives stalled in the past due to legal concerns, but they are enjoying a renaissance as part of broader initiatives, such as accountable care organizations and bundled payments. In the past, with so much of the focus on the legal aspects of gainsharing, the potential of gainsharing to preserve ...
Wong-Hammond Laca - - 2013
To succeed in today's complex economic environment, a not-for-profit health system requires an effective strategic capital planning process that harmonizes three elements: The organization's long-term business plan and mission. Existing financial resources and finance options available to support the organization's business plan. Financial risk and return on equity to the ...
Mann Lance - - 2013
Purchasing fraud leads to significant losses for healthcare entities and damages the reputation of the industry. Designing and implementing an effective internal control environment helps reduce the risk of fraud. An effective control environment includes a variety of policies, procedures, strategies, and tactics.
Farrell Molly L - - 2013
Healthcare providers should take eight steps to ensure their organizations are prepared for the potential risks associated with traumatic brain injuries: Review current procedures. Educate parents and caregivers. Create targeted programs for seniors. Adopt standard written protocols for providers for identification and treatment. Ensure proper and periodic follow-up with all ...
Landman James H - - 2013
Conversations on improving the value of health care often focus on clinical performance improvement efforts. Yet during Phase 2 of HFMA's Value Project research, CFOs time and again identified the revenue cycle as the place where their hospital's performance improvement efforts have begun.
Weeks William B - - 2013
In a recent study published in JAMA, the authors concluded that hospitals might have financial disincentives for reducing surgical complications. The study confirms some well-known healthcare financial management realities: Some procedures are more profitable than others, and sometimes complications generate positive returns for hospitals. But the study was flawed.
Bayod Javier - - 2013
Background: We used finite element analysis to evaluate three techniques for the correction of hammertoe and claw toe deformities: flexor digitorum longus tendon transfer (FDLT), flexor digitorum brevis tendon transfer (FDBT), and proximal interphalangeal joint arthrodesis (PIPJA). Methods: We performed a finite element analysis of FDLT and FDBT compared with ...
Fernandez Maria Luz Gonzalez - - 2013
Background: We assessed the efficacy of customized foot orthotic therapy by comparing reulceration rates, minor amputation rates, and work and daily living activities before and after therapy. Peak plantar pressures and peak plantar impulses were compared with the patients not wearing and wearing their prescribed footwear. Methods: One hundred seventeen ...
Hillstrom Howard J - - 2013
Background: In a previous pilot study of "cruisers" (nonindependent ambulation), "early walkers" (independent ambulation for 0-5 months), and "experienced walkers" (independent ambulation for 6-12 months), developmental age significantly affected the children's stability when walking and performing functional activities. We sought to examine how shoe structural characteristics affect plantar pressure distribution ...
Cauthon David J - - 2013
Hidradenomas are adenomatous tumors of sweat gland origin that are usually benign and can occur in any cutaneous skin surface. When malignant, the tumors have high recurrence rates and are often fatal. Because of their infrequency and clinical ambiguity, hidradenomas are often misdiagnosed as other soft-tissue masses. Radiation and chemotherapy ...
Zagrocki Laura - - 2013
Metastasis to the foot is rarely presented in the literature. We describe a 56-year-old woman with nonspecific pain in the left foot, ankle, and knee for 3 months. The patient was diagnosed as having urothelial carcinoma with metastasis to the left lower extremity, including the foot. This diagnosis was reached ...
Tummala-Narra Pratyusha - - 2013
Although discrimination has been found to contribute to psychological distress among immigrant populations, there are few studies that have examined the relationship between racial and ethnic discrimination in the school setting among foreign-born immigrant and U.S.-born immigrant-origin adolescents. This study examined the relationship between perceived discrimination by adults and peers ...
Wiley Shaun - - 2013
Immigrants to the United States face rejection from other Americans on the basis of their ethnic group membership. Among members of ethnic minority groups who were born in the United States, rejection is tied to higher ethnic identification and less positive attitudes toward the national majority. Relatively little research has ...
Rozet François - - 2013
High-risk prostate cancer (HRPC) has higher recurrence potential and multimodal treatment offers better outcomes in this population. The aim of this article is to comprehensively present the multimodal therapeutic options for HRPC. Review of the literature on HRPC with a literature selection based on evidence and practical considerations. Therapeutic options ...
Gaya Josep M - - 2013
Androgen deprivation therapy is the standard of care for the initial treatment of metastatic prostate cancer. However, the majority of these patients live long enough to experience disease progression despite castration. This scenario is defined as castration-resistant prostate cancer (CRPC) and has a poor outcome and limited options for treatment. ...
Lukas Rob - - 2013
The status of regional lymph nodes is the most important prognostic factor in early cervical cancer patients. Pelvic lymph node dissections are routinely performed as a part of standard surgical treatment. Systematic pelvic lymphadenectomy is associated with short- and long-term morbidities. This review discusses single components of the sentinel lymph ...
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