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Barry Nicolas P E - - 2013
Encapsulation of the platinum(IV) prodrug mitaplatin in block copolymer nanoparticles increases drug circulation time in the blood and reduces accumulation in the kidneys, as reported by Lippard and colleagues in this issue of ACS Nano. Importantly, controlled drug release from the nanoparticles produces long-term anticancer efficacy, with the prospect of ...
Krokhotin Andrey - - 2013
Protein collapse from a random chain to the native state involves a dynamical phase transition. During the process, new scales and collective variables become excited while old ones recede and fade away. The presence of different phases and many scales causes formidable computational bottle-necks in approaches that are based on ...
Levine Rachel M - - 2013
The success of common nonviral gene delivery vehicles, lipoplexes and polyplexes, is limited by the toxicity and instability of these charged molecules. Stealth liposomes could provide a stable, safe alternative to cationic DNA complexes for effective gene delivery. DNA encapsulations in three stealth liposomal formulations prepared by thin film, reverse ...
Thuresson Axel - - 2013
The free energy of interaction between parallel charged platelets with divalent counterions has been calculated using Monte Carlo simulations to investigate the electrostatic effects on aggregation. The platelets are primarily intended to represent clay particles. With divalent counterions, the free energy for two platelets or two tactoids (clusters of parallel ...
Eda Goki - - 2013
Semiconducting two-dimensional (2D) crystals such as MoS2 and WSe2 exhibit unusual optical properties that can be exploited for novel optoelectronics ranging from flexible photovoltaic cells to harmonic generation and electro-optical modulation devices. Rapid progress of the field, particularly in the growth area, is beginning to enable ways to implement 2D ...
Cha Wonsuk - - 2013
Zeolites are crystalline aluminosilicate minerals featuring a network of 0.3-1.5-nm-wide pores, used in industry as catalysts for hydrocarbon interconversion, ion exchangers, molecular sieves and adsorbents. For improved applications, it is highly useful to study the distribution of internal local strains because they sensitively affect the rates of adsorption and diffusion ...
Kim Yeon Hee - - 2013
To investigate the effects of meditation on anxiety, depression, fatigue, and quality of life in women who are receiving radiation therapy for breast cancer. Randomized, non-program controlled, parallel intervention clinical trial. The ASAN Cancer Center located in Seoul, Korea. The subjects of this study included 102 female breast cancer patients ...
Makanga Martine - - 2013
Bone morphogenetic proteins (BMP) have been shown to play crucial roles in not only lung and heart development, but also in the pathogenesis of pulmonary vascular remodeling in pulmonary hypertension (PH). We therefore hypothesized that BMP signaling could be altered in nitrofen-induced congenital diaphragmatic hernia (CDH) and associated PH. Pregnant ...
Peklar Jure - - 2013
Use of food supplements in the developed world is increasing in all age groups. With older age, the prevalence of multimorbidity and pharmacotherapy increases. Aim was to explore the prevalence of food supplement use among population aged≥50 years in Ireland and to identify factors associated with food supplement use. Cross-sectional ...
Pérez-Abalo Maria C - - 2013
Abstract NEURONIC-A 6.0 is a system for objective detection of hearing loss by means of the recording and analysis of auditory steady state responses. The system generates digitally Amplitude Modulated tones of different frequencies, allowing the mix of these and the simultaneous presentation through different transducers (earphone and bone vibrator) ...
Nakamura Atsutomo - - 2013
A dislocation in a crystalline material has dangling bonds at its core and a strong strain field in its vicinity. Consequently, the dislocation attracts solute atoms and forms a so-called Cottrell atmosphere along the dislocation. A crystalline dislocation can be used as a template to produce nanowires by selectively doping ...
Goberna Marta - - 2013
More than 300,000 tonnes of brewer's spent grain (BSG) is generated annually during beer production. This protein- and nutrient-rich by-product is mostly employed as an animal feedstuff. However, its marketability is compromised by its rapid deterioration owing to its high humidity and fermentable sugar content. Drying BSG can be achieved ...
Podmirseg Sabine M - - 2013
Wood ash addition to biogas plants represents an alternative to commonly used landfilling by improving the reactor performance, raising the pH and alleviating potential limits of trace elements. This study is the first on the effects of wood ash on reactor conditions and microbial communities in cattle slurry-based biogas reactors. ...
Domínguez Jorge - - 2013
In the present study the potential of the earthworm Eisenia andrei to modify chemical and microbiological properties, with a special focus on the nutrient content of fresh organic matter, was evaluated during 16 weeks of vermicomposting of cattle manure and sewage sludge. Samples were periodically collected in order to determine ...
Goy C B - - 2013
Abstract The ambulatory monitoring of biosignals involves the use of sensors, electrodes, actuators, processing tools and wireless communication modules. When a garment includes these elements with the purpose of recording vital signs and responding to specific situations it is call a 'Smart Wearable System'. Over the last years several authors ...
Khaiboullina Svetlana F - - 2013
Hantaviruses are negative strand RNA species that replicate predominantly in the cytoplasm. They also activate numerous cellular responses, but their involvement in nuclear processes is yet to be established. Using human umbilical vein endothelial cells (HUVECs), this study investigates the molecular finger-print of nuclear transcription factors during hantavirus infection. The ...
SzuliƄska M M Department of Internal Medicine, Poznan University of Medical Sciences, - - 2013
Obesity and smoking are leading causes of morbidity and mortality worldwide. Cross-sectional studies indicate that heavy smoking may be associated with a greater risk of obesity. While there are important unresolved issues in relation to the effect of smoking on body weight, there is increasing evidence that smoking is conducive ...
Park Kyung-Jin KJ University of Leipzig, Department of Cariology, Endodontology and Periodontology, Liebig Street 12, Haus 1, 04103 Leipzig, Germany. - - 2013
ABSTRACT. In clinical dental practice, it is often difficult or even impossible to detect and assess interfacial adhesive defects at adhesive restorations by means of visual inspection or other established diagnostic methods. However, nondestructive optical coherence tomography (OCT) may provide a better picture in this diagnostic scenario. The aim of ...
Moustafa Ahmed A AA New Jersey Health Care System, East Orange, New Jersey, USA. - - 2013
Prior studies have not tested individual differences or effects of medication dosage on stimulus-response learning in patients with Parkinson's disease (PD). In the current study, we investigated the effects of motor variables (including tremor, akinesia, and disease duration) as well as dopaminergic medication dosage on learning in unmedicated PD patients, ...
Bailey Rj - - 2013
The Australian Medical Journal is important to Australian anaesthesia in that, as well as associated editorials, it recorded the first use of ether for surgical operations. Though it survived from 1 August 1846 until 1 October 1847, its first issue was surrounded with mystery, referring to an earlier publication. Proof ...
Chen Shan-Lin - - 2013
Schwannomatosis is a recently recognized peripheral nerve polyneoplasm with clinical characteristics and a genetic background that differ from those of neurofibromatosis 2 (NF2). The diagnostic and treatment criteria of this rare disorder are herein discussed. The data of 180 patients who underwent operations for benign schwannomas from 2003 to 2012 ...
Marsico Fabio - - 2013
Systemic inflammatory diseases are associated with increased cardiovascular morbidity and mortality. The link between inflammatory and cardiovascular diseases can be attributed to the coexistence of classical risk factors and inflammatory mechanisms activated during systemic inflammatory diseases involving the immune system. Unfavorable metabolic effects of anti-inflammatory drugs can also contribute to ...
Gijon-Nogueron Gabriel A - - 2013
Background: Women's feet change during pregnancy owing to hormonal and anatomical changes, thus having a strong influence on the decrease in their quality of life during pregnancy. This preliminary study aimed to value the anthropometric and positional changes that affect their feet. Methods: Ten pregnant women were measured during their ...
Alonso Eliana Noelia EN Science and Technology Center, Center of Renewable Natural Resources of the Semi-Arid Zone (CERZOS), National Scientific and Technical Research Council (CONICET), Bahia Blanca, Buenos Aires, - - 2013
It is already known that the Maitake (D-Fraction) mushroom is involved in stimulating the immune system and activating certain cells that attack cancer, including macrophages, T-cells, and natural killer cells. According to the U.S. National Cancer Institute, polysaccharide complexes present in Maitake mushrooms appear to have significant anticancer activity. However, ...
Salmon David P DP Department of Neurosciences, University of California, San Diego, La Jolla, CA 92093-0948, USA. - - 2013
This study examined the impact of age and apolipoprotein E (APOE) genotype on the rate of cognitive decline in nondemented elderly participants in a simulated Alzheimer's disease (AD) primary prevention treatment trial carried out by the Alzheimer's Disease Cooperative Study. Cognitive tests were administered at baseline and at four subsequent ...
Park Bong Hee - - 2013
Upper urinary tract urothelial carcinoma (UTUC) is relatively uncommon. Radical nephroureterectomy with an ipsilateral bladder cuff excision has been the gold standard treatment for UTUC. However, recent advances in technology have made possible the increased use of endoscopic management for the treatment of UTUC. The definitive goal of endoscopic management ...
Wolter Tilman - - 2013
Despite the good clinical results elicited by spinal cord stimulation (SCS), the physiological basis of action of SCS is widely unknown. Inhibition of somatosensory evoked potential (SEP) amplitudes by SCS has been described, but it is unclear whether this displays dose dependency. Moreover, it is unknown whether the pain-relieving effect ...
Offringa Martin - - 2013
Febrile seizures occurring in a child older than one month during an episode of fever affect 2% to 4% of children in Great Britain and the United States and recur in 30%. Rapid-acting antiepileptics and antipyretics given during subsequent fever episodes have been used to avoid the adverse effects of ...
Erdner Anette - - 2013
To a large extent today, caring for people with mental illness takes place outside of institutional care. Sometimes, assistance from a special police group may be required to commit the patient to a hospital for continued psychiatric treatment. The aim of this study was to describe a group of police ...
Wodrich Elizabeth - - 2013
Rural nurses are expected to be competent and confident caregivers for patients of all ages and disease states. Rural nurse educators are challenged with creating appropriate learning environments to assess and maintain nursing competencies in resource-limited areas. This project describes and evaluates the utilization of a simulation manikin from a ...
Verbrugghe Adronie - - 2013
Research in various species has indicated that diets deficient in labile methyl groups (methionine, choline, betaine, folate) produce fatty liver and links to steatosis and metabolic syndrome, but also provides evidence of the importance of labile methyl group balance to maintain normal liver function. Cats, being obligate carnivores, rely on ...
Loughnan Te - - 2013
Muscle relaxants were introduced into clinical practice in the early 1940s. From 1949, assessments were being made of the efficacy of various agents in awake volunteers, usually the researchers themselves. From the early to mid 1950s, while interest in using muscle relaxants was keen, concern emerged in the surgical literature ...
Wu Jing - - 2013
Vancomycin-resistant Enterococci (VRE) cause serious infections that are difficult to treat. We carried out this study to determine the mutant prevention concentration (MPC) of linezolid when combined with minocycline against VRE strains, to determine the mechanism of drug resistance in vitro, and to provide a theoretical basis for the rational ...
Grego Susanna - - 2013
Background. The diagnosis and surgical treatment of patients with Marfan syndrome remain controversial. It is of utmost importance to identify patients at risk for acute aortic events to establish the correct surgical timing and the appropriate surgical treatment.Methods. From May 2008 to December 2012, 500 patients were screened at the ...
Sagynbekov Ken Imanak - - 2013
Objective: Studies of maternal mortality that use data from multiple countries often identify statistically significant correlates and interpret them as factors relevant to policy. This study was designed to address the fragility of a statistical association between the maternal mortality rate and its main correlates, and to assess the relevance ...
Suh Jun-Gyo - - 2013
Although direct-vision internal urethrotomy can be performed for the management of short, bulbar urethral strictures, excision and end-to-end anastomosis remains the best procedure to guarantee a high success rate. We performed a retrospective evaluation of patients who underwent bulbar end-to-end anastomosis to assess the factors affecting surgical outcome. We reviewed ...
Manchikanti Laxmaiah - - 2013
Both the Office of Inspector General (OIG) and reports from studies of the utilization of facet joint interventions have expressed that explosive increases in facet joint interventions provided to spinal pain patients are a major concern. The study is designed to assess the growth of facet joint interventions in managing ...
Liu Sha - - 2013
MicroRNAs (miRNAs) control gene expression by destabilizing target transcripts and inhibiting their translation. Aberrant expression of miRNAs has been described in many human diseases, including schizophrenia. However, the effects on miRNA expression in response to antipsychotic treatment in peripheral circulation have not been thoroughly examined. Using quantitative real-time PCR (qRT-PCR), ...
Cauthon David J - - 2013
Hidradenomas are adenomatous tumors of sweat gland origin that are usually benign and can occur in any cutaneous skin surface. When malignant, the tumors have high recurrence rates and are often fatal. Because of their infrequency and clinical ambiguity, hidradenomas are often misdiagnosed as other soft-tissue masses. Radiation and chemotherapy ...
Hsieh Ya-Lun - - 2013
Abstract This study was undertaken to determine whether there was an association between fine particles (PM2.5) levels and hospital admissions for congestive heart failure (CHF) in Taipei, Taiwan. Hospital admissions for CHF and ambient air pollution data for Taipei were obtained for the period 2006-2010. The relative risk of hospital ...
Vetvicka Vaclav V Department of Pathology, University of Louisville, Louisville, Kentucky 40202, USA. - - 2013
Despite the rather common presence of humic acid (HA), our full knowledge of its biological effect is still lacking. In this article, we first performed a physicochemical characterization of several HAs, and next, we evaluated their ability to affect interleukin-2 secretion, antibody secretion, wound healing (an in vitro model using ...
Nikulina Valentina V Psychology Department, John Jay College of Criminal Justice, City University of New York, New York, NY 10019, - - 2013
There is extensive evidence of negative consequences of childhood maltreatment for IQ, academic achievement, and posttraumatic stress disorder (PTSD), and increased attention to neurobiological consequences. However, few prospective studies have assessed the long-term effects of abuse and neglect on executive functioning. This study examined whether childhood abuse and neglect predicts ...
Lee Jeong Kuk - - 2013
Although percutaneous nephrolithotomy (PCNL) has been accepted as a standard method for the management of large renal stones, the incidence of renal hemorrhage is relatively high. This study investigated the variables that affect bleeding during PCNL. The medical records of 370 patients who underwent PCNL by a single surgeon from ...
Manchikanti Laxmaiah - - 2013
  The high prevalence of persistent low back pain and growing number of diagnostic and therapeutic modalities employed to manage chronic low back pain and the subsequent impact on society and the economy continue to hold sway over health care policy. Among the multiple causes responsible for chronic low back ...
Ren Wei-Hong - - 2013
Patients with maxillary tumor often suffer from trismus after maxillectomy, which could turn out to be a permanent sequela without proper intervention. In this study, the efficacy of mouth opening exercises in preventing and treating trismus was observed in patients with maxillary tumor early after their operations. At the same ...
Di Eusanio Marco - - 2013
Aortic disease is the most life-threatening complication of Marfan syndrome. Over the last decades, improved medical management and surgical results of prophylactic aortic interventions on the aortic root have dramatically increased expectancy of life in Marfan syndrome patients. As a result, the number of Marfan syndrome patients requiring secondary interventions ...
Patry Jérôme - - 2013
Background: Clinical recommendations for the prevention and healing of diabetic foot ulcers (DFUs) are somewhat clear. However, assessment and quantification of the mechanical stress responsible for DFU remain complex. Different pressure variables have been described in the literature to better understand plantar tissue stress exposure. This article reviews the role ...
Uma Sundaram - - 2013
Abstract Mucuna pruriens, an underutilized native legume of South India has been reported to have high levels of L-Dopa, and used in the treatment of Parkinson's disease. Cellular damage arising from reactive oxygen and nitrogen species is said to cause neurodegenerative disorders. Antioxidants could assuage this oxidative damage of tissue ...
Klamer Silke - - 2013
Objective: Episodic memory processes can be investigated using different functional MRI (fMRI) paradigms. The purpose of the present study was to examine correlations between neuropsychological memory test scores and BOLD signal changes during fMRI scanning using three different memory tasks. Method: Twenty-eight right-handed healthy subjects underwent three paradigms, (a) a ...
Tanaka Kazushi - - 2013
To evaluate the efficacy of using 3-tesla (T) magnetic resonance imaging (MRI) diagnosis of extracapsular extension (ECE) for decision-making about neurovascular bundle (NVB) preservation in robot-assisted radical prostatectomy (RARP) for prostate cancer (PC). We prospectively collected data on PC patients (n=67) who underwent preoperative 3-T MRI before RARP. The choice ...
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