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Results 301 - 350 of 6819
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Tagare Amit - - 2013
OBJECTIVE: To assess outcome of InSuRE (Intubation, Surfactant and Rapid Extubation) in managing preterm neonates with respiratory distress syndrome (RDS). METHODS: Preterm neonates fulfilling inclusion criteria were enrolled after obtaining informed parental consent. Criteria for success of InSuRE was predefined. Proportion of neonates with success or failure of InSuRE was ...
Sasaki Nobuo - - 2013
The nitrofuran antimicrobial agent, furazolidone (FZ), is still used in veterinary medicine in some countries in the Middle and Far Eastern countries. The present study aimed to investigate the effects of successive bolus doses of FZ and its metabolite 3-amino-2-oxazolidinone (AOZ) on cytochrome P450 (CYP)-related activities in the livers of ...
Moroney James V - - 2013
This review presents an overview of the two ways that cyanobacteria, algae, and plants have adapted to high O2 and low CO2 concentrations in the environment. First, the process of photorespiration enables photosynthetic organisms to recycle phosphoglycolate formed by the oxygenase reaction catalyzed by ribulose-1,5-bisphosphate carboxylase/oxygenase (Rubisco). Second, there are ...
Perreault Melissa L - - 2013
The pharmacological modification of dopamine transmission has long been employed as a therapeutic tool in the treatment of many mental health disorders. However, as many of the pharmacotherapies today are not without significant side effects, or they alleviate only a particular subset of symptoms, the identification of novel therapeutic targets ...
Morales-Roselló José - - 2013
Abstract Objective. To determine the existence of Doppler changes in the fetal vertebral, middle cerebral and umbilical arteries prior to term labor. Methods. Five hundred and twenty eight Doppler examinations of the vertebral (VA), middle cerebral (MCA) and umbilical (UA) arteries resistance indices (RI) were performed between 37 and 41 ...
Yang Baiyu - - 2013
Three polymorphic sites at chromosome 8q24 (rs7837328, rs10808555, rs6983267) have been associated with risk for colorectal adenomas. It was also previously reported that the single nucleotide polymorphism (SNP) rs6983267 may enhance Wnt signaling, which regulates cell proliferation. To investigate associations between the 8q24 variants and colorectal epithelial cell proliferation in ...
Lygidakis N N - - 2013
BACKGROUND: Solitary median maxillary central incisor syndrome [SMMCI] is an extremely rare anomaly, especially when no other abnormalities are present. The defect is often found together with various nasal abnormalities and short stature with or without decreased levels of growth hormone. In more severe cases, SMMCI has been associated with ...
Zhang Zhengfeng - - 2013
PURPOSE: To identify anterior spinal artery (ASA) infarct or occlusion by CT angiography (CTA) in patients with cervical spondylotic myelopathy (CSM). METHODS: Fourteen patients with CSM were performed CTA of ASA after admission. T2-weighted hyperintensity of MR image was compared with image of CTA of ASA. RESULTS: All patients presented ...
Stang Andreas - - 2013
The aim of this study was to assess the association between the introduction of the nationwide mammography screening program (MSP) and breast cancer surgery rates in Germany 2005-2009. We used nationwide DRG hospitalization files (2005-2009) and analyzed surgery rates for the treatment of invasive and in situ breast cancer in ...
Goedken Amber M - - 2013
Our objective was to identify factors related to receipt of the recommended number of well-child visits in insured children. We hypothesized parent insurance status would be related to receipt of well-child visits, with those with uninsured parents more likely to have fewer visits than recommended. Data for the study came ...
Parsaik Ajay K AK Department of Neurology, Mayo Clinic, 200 1st street, SW, Rochester, MN, 55905, USA, - - 2013
To perform a systematic review and meta-analysis of clinical trials evaluating the efficacy and safety of midodrine in orthostatic hypotension (OH). We searched major databases and related conference proceedings through June 30, 2012. Two reviewers independently selected studies and extracted data. Random-effects meta-analysis was used to pool the outcome measures ...
John Dolly A - - 2013
Using data from 1,530 Asian respondents of the 2002-2003 National Latino and Asian American Study, we examined how nativity and occupational class are associated with uninsurance, no routine physical check-up in the past year and no dental/eye exam use in the past year using weighted multivariate logistic regression models. Recent ...
Christopher Matthew E - - 2013
Imaging and analyzing gunshot residue (GSR) particles using the scanning electron microscope equipped with an energy dispersive X-ray spectrometer (SEM-EDS) is a standard technique that can provide important forensic evidence, but the discrimination power of this technique is limited due to low sensitivity to trace elements and difficulties in obtaining ...
Fullana M A - - 2013
BACKGROUND: The size of particular sub-regions within the ventromedial prefrontal cortex (vmPFC) has been associated with fear extinction in humans. Exposure therapy is a form of extinction learning widely used in the treatment of obsessive-compulsive disorder (OCD). Here we investigated the relationship between morphometric measurements of different sub-regions of the ...
Inoue Takahiro - - 2013
Persistent fifth aortic arch (PFAA) associated with interruption of the fourth aortic arch is a rare malformation, usually requiring surgical intervention in childhood. A 51-year-old woman developed a distal aortic arch aneurysm associated with PFAA after patch aortoplasty for coarctation of the aorta at the age of 18. To our ...
Wei Qiang Wei - - 2013
To investigate the proliferation and differentiation of the human dental pulp cells (hDPCs) on the bioactive scaffolds. Primary HDPCs were harvested from impacted third molars of healthy adult individuals (18-25 years of age) by enzyme digestion, expanded and cultured. The cells used for this investigation were the 4 th passage. ...
Kim Kwon-Ho - - 2013
Direct current (DC) piezoelectric power generator is promising for the miniaturization of a power package and self-powering of nanorobots and body-implanted devices. Hence, we report the first use of two-dimensional (2D) zinc oxide (ZnO) nanostructure and an anionic nanoclay layer to generate piezoelectric DC output power. The device, made from ...
Yurtkuran Zeynep - - 2013
Monitoring of pesticide residues in water and sediments was conducted for the coastal shallow Karaboğaz Lake, northern Turkey. During a one-year study period, eight pesticides (malathion, etofenprox, molinate, oxamyl, propamocarb hydrochloride, tebufenozide, linuron, piperonyl butoxide) were detected in water and in sediments, all at μg/L and μg/kg concentrations, respectively. Temporal ...
Thomsen Martin M Center for Biological Sequence Analysis, Department of Systems Biology, Technical University of Denmark, Building 208, Kemitorvet, Lyngby 2800, - - 2013
The identification of peptides binding to major histocompatibility complexes (MHC) is a critical step in the understanding of T cell immune responses. The human MHC genomic region (HLA) is extremely polymorphic comprising several thousand alleles, many encoding a distinct molecule. The potentially unique specificities remain experimentally uncharacterized for the vast ...
Holopainen Jari - - 2013
Several studies show a peak in suicide rates during springtime and suggest differences in the seasonal variation of suicides. However, the seasonal distribution of the temperature impact on suicide is less clear. This study investigated the relationship between diurnal temperature range (DTR) on suicide mortality. Daily temperature and suicide data ...
Buján Nuria - - 2013
Primary coenzyme Q10 (CoQ10) deficiencies are associated with mutations in genes encoding enzymes important for its biosynthesis and patients are responsive to CoQ10 supplementation. Early treatment allows better prognosis of the disease and therefore, early diagnosis is desirable. The complex phenotype and genotype and the frequent secondary CoQ10 deficiencies make ...
Yang Guang - - 2013
Diabetic nephropathy (DN) is one of the most common microvascular complications of diabetic mellitus. Its treatment by now is mainly focused on the suppression of the renin-angiotonin system and the control of relative risk factors such as hypertention, hyperglycemia and so on, whose effectiveness is disappointed. Stem cells can be ...
Zhang Jin - - 2013
Argonaute (Ago) proteins have been demonstrated to be widely expressed and involved in post-transcriptional gene silencing and thus play key roles in carcinogenesis. Nevertheless, little is known about the specific role of Ago2 in gastric cancer (GC). Thus, we aimed to study the expression of Ago2 in 363 primary GC, ...
Avdievich Nikolai I NI Department of Neurosurgery, Yale University, New Haven, CT, - - 2013
Transceiver surface coil arrays improve transmit performance (B1/√kW) and B1 homogeneity for head imaging up to 9.4 T. To further improve reception performance and parallel imaging, the number of array elements must be increased with a corresponding decrease in their size. With a large number of small interacting antennas, decoupling ...
Chapuy Claudia I - - 2013
OBJECTIVE: To assess clinical success and safety of endoscopic pharyngoesophageal dilation after chemoradiation or radiation for head and neck cancer and to identify variables associated with dilation failure. STUDY DESIGN: Case series with chart review. METHODS: Between 2000 and 2008, a total of 111 patients treated with chemoradiation or radiation ...
Acevedo María Belén - - 2013
RATIONALE: It is important to study age-related differences that may put adolescents at risk for alcohol-related problems. Adolescents seem less sensitive to the aversive effects of ethanol than adults. Less is known of appetitive effects of ethanol and stress modulation of these effects. OBJECTIVES: This study aims to describe the ...
Lötsch Jörn - - 2013
Surrogates may provide easy and quick access to information about pharmacological parameters of interest that can be directly measured only with difficulty. Surrogates have been proposed for opioid blood concentrations to replace invasive sampling, serving as a basis for target-controlled infusion systems to optimize analgesia. We aimed at identifying surrogates ...
Kim Bora - - 2013
MicroRNAs (miRNAs) regulate gene expression through degradation and/or translational repression of target mRNAs. Dysregulations in the miRNA machinery may be involved in carcinogenesis of colorectal cancer (CRC). The purpose of the current study was to evaluate the DiGeorge syndrome critical region gene 8 (DGCR8) and argonaute 2 (AGO2) mRNA expression ...
Lenk Christine - - 2013
PURPOSE: Human factor VIIa (FVIIa) is commonly used as bypassing therapy to treat bleeding episodes in hemophilia patients with neutralizing antibodies to factors VIII (FVIII) or IX (FIX). There is a need for a suitable animal model to assess the immunogenicity of new FVIIa products during preclinical development. The aim ...
Nakazawa Yoshihisa - - 2013
A microscopic technique combining spectral confocal laser scanning microscopy with a lipophilic fluorescent dye, Nile red, which can emit trans-polyisoprene specific fluorescence, was developed, and unmixed images of synthesized trans-polyisoprene in situ in Eucommia ulmoides were successfully obtained. The images showed that trans-polyisoprene was initially synthesized as granules in non-articulated ...
Fani L - - 2013
Obesity is one of the greatest public health challenges of the 21st century. Obesity is currently responsible for ∼0.7-2.8% of a country's health costs worldwide. Treatment is often not effective because weight regulation is complex. Appetite and energy control are regulated in the brain. Melanocortin-4 receptor (MC4R) has a central ...
Kanba Shigenobu - - 2013
The Japanese Society of Mood Disorders established a committee for treatment guidelines of mood disorders, which created the first edition of a treatment guideline for bipolar disorders on 10 March 2011. The committee has now created a second edition, which we report here. In creating this treatment guideline, the first ...
Shek Yuen Lai - - 2013
Guanine-rich DNA sequences that may form G-quadruplexes are located in strategic DNA loci with the ability to regulate biological events. G-quadruplexes have been under intensive scrutiny owing to their potential to serve as novel drug targets in emerging anticancer strategies. Thermodynamic characterization G-quadruplexes is an important and necessary step in ...
Connolly Michael - - 2013
INTRODUCTION: Dronedarone, a non-iodinated derivative of amiodarone, has been approved for use as a second-line agent for atrial fibrillation (AF). Following reports of possible liver injury during routine post-license monitoring, the European Medicines Agency (EMA) recommended regular liver function test (LFT) monitoring. Despite this recommendation, an audit of patients in ...
Huang Yu-Chung - - 2013
Several revisions of International Prognostic Index (IPI) have been proposed for patients with diffuse large B-cell lymphoma (DLBCL) after the introduction of rituximab. Expanding evidence suggests that baseline absolute lymphocyte count (ALC) is also an independent factor for outcome prediction. We investigated the optimal prognostic model for these patients in ...
Holzer Stefan - - 2013
Dementia is a complex progressive syndrome characterised by impairment of cognition (including memory, language, visuospatial skills and executive function), changes in personality and diminished activities of daily living. The impact of dementia is enormous and poses a huge challenge to patients, their carers, society at large and health systems around ...
Soljanik Irina - - 2013
BACKGROUND: Botulinum toxin A (BoNTA) is increasingly used for therapy of neurogenic detrusor overactivity (NDO) refractory to antimuscarinics or where patients are experiencing antimuscarinic-related side effects. OBJECTIVE: The objective was to compare and critically discuss the reported efficacy and safety of BoNTA in adults with neurogenic bladder dysfunction. DATA SOURCES: ...
Lopes Tátila Martins - - 2013
Previous studies demonstrated cognitive impairments in spinocerebellar ataxia type 3 (SCA3/MJD); however, there is no consensus about the cognitive domains affected and the correlation with structural brain abnormalities. We investigated the neuropsychological profile and 3T-MRI findings, including high-resolution T1-images, diffusion tensor imaging and magnetic resonance spectroscopy of 32 patients with ...
Tan Angel - - 2013
The diversity of lipid excipients available commercially has enabled versatile formulation design of lipid-based drug delivery systems for enhancing the oral absorption of poorly water-soluble drugs, such as emulsions, microemulsions, micelles, liposomes, niosomes and various self-emulsifying systems. The transformation of liquid lipid-based systems into solid dosage forms has been investigated ...
Zhu Lei - - 2013
OBJECTIVES: To describe three cases of cryptococcus neoformans meningitis and evaluate their cellular immunity. METHODS: This study involved three cases of cryptococcus neoformans meningitis admitted to Children's Hospital of Shanxi Province between July 2010 and July 2011. Clinical presentations, laboratory findings, treatment and outcome in these cases has been discussed. ...
Allen Kyle P - - 2013
OBJECTIVES/HYPOTHESIS: To determine the prevalence of elevated intracranial hypertension in patients with spontaneous cerebrospinal fluid otorrhea (SCSFO). STUDY DESIGN: Case series with chart review at a tertiary care academic medical center following institutional review board approval. METHODS: A retrospective review was performed of patients undergoing operative repair of SCSFO between ...
Pieczarka J C - - 2013
The species of genera Uroderma and Artibeus are medium-sized bats belonging to the family Phyllostomidae and subfamily Stenodermatinae (Mammalia, Chiroptera) from South America. They have a wide distribution in the Neotropical region, with two currently recognized species in Uroderma and approximately 20 species in Artibeus. These two genera have different ...
Natsugoe Shoji - - 2013
Lymph node micrometastasis (LNM) can now be detected thanks to the development of various biological methods such as immunohistochemistry (IHC) and reverse transcription-polymerase chain reaction (RT-PCR). Although several reports have examined LNM in various carcinomas, including gastrointestinal (GI) cancer, the clinical significance of LNM remains controversial. Clinically, the presence of ...
Li Jiakun - - 2013
Simplexides constitute a unique group of immunosuppressive glycolipids that demonstrate antiproliferative activities against activated T-cell lymphocytes via a unique non-cytotoxic inhibition. To investigate the structure-activity relationship of the varied long-chain secondary alcohols on simplexides, we developed an efficient and divergent route to the synthesis of simplexides and congeners, taking advantage ...
Zhang Xiao-Ping - - 2013
The first luminescent Bi-Cd-organic framework, Bi2Cd(2,6-pdc)4(H2O)2·H2O (2,6-H2pdc = pyridine-2,6-dicarboxylate), has been synthesized by using bismuth (Bi) oxides and cadmium (Cd) salts as metal sources under hydrothermal conditions. Tunable and white light luminescence was obtained through the doping of different Ln(3+) ions into the Bi-Cd-organic framework.
Ichimura Hideo - - 2013
Left upper lobectomy may be followed by complications such as thrombus formation in a stump of the left superior pulmonary vein (LSPV), which may cause systemic embolization. We have encountered four such cases, which account for 3.4% of all left upper lobectomies performed at our institution. Right renal infarction was ...
Aseem Obaidullah - - 2013
BACKGROUND: Cubilin is an endocytic receptor that is necessary for renal and intestinal absorption of a range of ligands. Endocytosis mediated by cubilin and its co-receptor megalin is the principal mechanism for proximal tubule reabsorption of proteins from the glomerular filtrate. Cubilin is also required for intestinal endocytosis of intrinsic ...
Grotta Milena Baptistella - - 2013
BACKGROUND: A clear relationship between asthma and obesity has been reported, but the mechanisms remain unclear. The aim of this study was to evaluate the influence of obesity on eosinophil activity (chemotaxis and adhesion) in asthmatic children and adolescents compared with cells from healthy volunteers. METHODS: Asthmatic obese (AO), asthmatic ...
Huang Jian Lin - - 2013
Radical prostatectomy is one of the most effective treatments for men with clinically localized prostate cancer. Though technical innovations,especially laparoscopic techniques,have developed rapidly for the last decade, urinary incontinence remains one of the most troubling side effects of the operation. While the injury of urethral sphincter and its innervations was ...
Fajín José L C - - 2013
The adsorption of cysteine onto the intrinsically chiral gold surface, Au(321)R,S, was investigated by means of a periodic supercell density functional theory approach. The results are compared with those obtained at the same level of theory with a non-chiral surface having the same terrace orientation, the Au(111) surface. Neutral and ...
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