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Results 301 - 350 of 6785
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Dandempally A - - 2013
OBJECTIVE: The aim of this study was to formulate a regression equation for calculating working lengths in primary molars using EAL (Root ZX and Ipex) for teeth with and without resorption and to evaluate, in vivo, the accuracy of the electronic apex locators in determining working lengths in primary teeth ...
Kristóf Endre - - 2013
Apoptotic cells express eat-me signals which are recognized by several receptors mainly on professional phagocytes of the mononuclear phagocyte system. This "engulfment synapse" can define a safe and effective clearance of apoptotic cells in order to maintain tissue homeostasis in the entire body. We show that the expression of four ...
Baki Elif Doğan - - 2013
Cardiopulmonary bypass (CPB) contributes to the secretion of anti-inflammatory cytokines that mediate the inflammatory response observed during open heart surgery. In addition to many factors, type of anesthesia management affects immune response and central nervous system in cardiac surgery. The aim of this study was to assess the effect of ...
Liu Hongliang - - 2013
Self-cleaning on various surfaces is obtained using the facile approach of modifying the surface with a thin organogel film. The film not only absorbs oil but also holds it in a crosslinked network, which endows the material with an excellent self-cleaning ability. This facile method can be applied to various ...
Holzer Stefan - - 2013
Dementia is a complex progressive syndrome characterised by impairment of cognition (including memory, language, visuospatial skills and executive function), changes in personality and diminished activities of daily living. The impact of dementia is enormous and poses a huge challenge to patients, their carers, society at large and health systems around ...
Dimtsas Georgios S - - 2013
ABSTRACT Angiogenesis leads to new blood vessel formation and is implicated in both physiological and pathological situations. VEGF family is the major mediator of this process. The aim of our study was to evaluate the expression of VEGF-A, VEGFR-1 and VEGFR-2 and their correlation with clinicopathological parameters and prognosis in ...
De Wolf Daniel - - 2013
Sudden cardiac death in young athletes is a devastating event. Screening programs have been proposed to prevent sudden cardiac death in young athletes. Mortality rates and causes of death differ among young adults and children. Children have a considerably lower incidence of sudden cardiac death. Data lack to compare athletes ...
Salek David - - 2013
ABSTRACT Although a prognostic model (MIPI=MCL International prognostic Index) for patients with mantle cell lymphoma (MCL) was established, its clinical significance for daily practice in the rituximab era remains controversial. Data of 235 unselected MCL patients from the Czech Lymphoma Group Database were analysed. MIPI, simplified MIPI (s-MIPI) and Ki-67 ...
Aigner F - - 2013
PURPOSE: The aim of this study was to compare postoperative pain between the open tension-free plug and patch (PP) technique and the totally extraperitoneal patch (TEP) hernioplasty. METHODS: One hundred and fifty-four male patients with unilateral inguinal hernia were randomized to undergo PP and TEP from 2005 to 2009. Pain ...
Buffalari Deanne M - - 2013
RATIONALE: Cue exposure therapy, which attempts to limit relapse by reducing reactivity to cocaine-paired cues through repeated exposures, has had limited success. OBJECTIVES: The current experiments examined cocaine cue-induced anxiogenesis and investigated whether a model of cue exposure therapy would reduce reinstatement of cocaine seeking in rats with a history ...
Brass Eric P - - 2013
Peripheral artery disease (PAD) is the result of extensive atherosclerosis in the arterial supply to the lower extremities. PAD is associated with increased systemic cardiovascular morbidity and mortality as well as substantial disability due to walking impairment. Claudication is the classic symptom of leg pain with walking that is relieved ...
Miyazaki Taeko - - 2013
The retinal ganglion cell distribution, which is known to reflect fish feeding behavior, was investigated in juvenile Pacific bluefin tuna Thunnus orientalis. During the course of examination, regularly arrayed cells with a distinctive larger soma, which may be regarded as motion-sensitive cells, were found. The topographical distribution of ordinary-sized ganglion ...
Chiche Laurence - - 2013
BACKGROUND: Hepatocellular carcinoma in noncirrhotic liver (HCCNC) is rare. This tumor has a particular epidemiology and presentation, and it requires specific treatment, compared with HCC in cirrhotic liver. The aims of this study were to determine the survival and recurrence rates, prognostic factors, and optimum treatment of HCCNC and to ...
Sugimoto Takuya - - 2013
BACKGROUND: Spasm of the internal anal sphincter is considered to be one of the causes of pain in anal diseases. We have evaluated the effects of topical diltiazem on postoperative pain after hemorrhoidectomy. METHODS: Sixty-two patients were randomly assigned to receive a 2 % diltiazem gel (n = 32) or a placebo gel ...
Türk Figen - - 2013
BACKGROUND: We compared the number of incisions, surgical procedures, hospital duration, and complications in hydatid cyst patients with unilateral or bilateral thoracic involvement and concomitant involvement of the extrathoracic organs. METHODS: A total of 76 hydatid cyst cases surgically treated between the years 2007 and 2012 were divided into three ...
Chichom Mefire Alain - - 2013
BACKGROUND: Surgeons are scarce in African countries. There is still a need to rely on general practitioners to perform a number of selected procedures. Their training needs to take these facts into consideration. The aim of this study was to evaluate the pattern of surgical procedures performed in a level ...
Camporeale Angelo - - 2013
BACKGROUND: Attention-deficit hyperactivity disorder (ADHD) is a neuropsychiatric disorder that begins in childhood. Atomoxetine is a selective inhibitor of the presynaptic norepinephrine transporter. Several studies have demonstrated the safety and efficacy of atomoxetine in the treatment of ADHD. OBJECTIVE: The objective of this analysis was to provide additional information on ...
Lötsch Jörn - - 2013
Surrogates may provide easy and quick access to information about pharmacological parameters of interest that can be directly measured only with difficulty. Surrogates have been proposed for opioid blood concentrations to replace invasive sampling, serving as a basis for target-controlled infusion systems to optimize analgesia. We aimed at identifying surrogates ...
Conway Rebecca E - - 2013
Prostate specific membrane antigen (PSMA) is a pro-angiogenic cell-surface protease that we previously demonstrated regulates blood vessel formation in a laminin and integrin β1-dependent manner. Here, we examine the principal mechanism of PSMA activation of integrin β1. We show that digesting laminin sequentially with recombinant matrix metalloprotease-2 (MMP-2) and PSMA ...
Tyrer Hayley E - - 2013
Otitis media (OM) is a common cause of childhood hearing loss. The large medical costs involved in treating this condition have meant that research to understand the pathology of this disease and identify new therapeutic interventions is important. There is evidence that susceptibility to OM has a significant genetic component, ...
Huang Baorong - - 2013
Based on regional heterogeneity of environmental characteristics and factors influencing those characteristics, environmental units may be classified into homogeneous zones. Then, essential strategies and mitigation measures in each zone may be developed and environmental quality may be holistically improved using a system of environmental management regionalization (EMRZ). Here, an EMRZ ...
Lopes Tátila Martins - - 2013
Previous studies demonstrated cognitive impairments in spinocerebellar ataxia type 3 (SCA3/MJD); however, there is no consensus about the cognitive domains affected and the correlation with structural brain abnormalities. We investigated the neuropsychological profile and 3T-MRI findings, including high-resolution T1-images, diffusion tensor imaging and magnetic resonance spectroscopy of 32 patients with ...
Tran K D - - 2013
BACKGROUND: The standard treatment for patients with pemphigus vulgaris has long consisted of high-dose glucocorticoids. Studies regarding the use of methotrexate in pemphigus vulgaris date back to 1968, but few have quantitatively described a steroid-sparing effect conferred by methotrexate. OBJECTIVE: We sought to evaluate the efficacy of methotrexate in 23 ...
Seyer Lauren A - - 2013
To use optical coherence tomography (OCT) and contrast letter acuity to characterize vision loss in Friedreich ataxia (FRDA). High- and low-contrast letter acuity and neurological measures were assessed in 507 patients with FRDA. In addition, OCT was performed on 63 FRDA patients to evaluate retinal nerve fiber layer (RNFL) and ...
Li Chuan Silvia - - 2013
PURPOSE: To understand orthopedic surgeons' views, preferences, and awareness on "treatment gap" and various conservative and surgical treatments for early to mid-stage knee osteoarthritis (OA). METHODS: A self-administered questionnaire on the treatment of knee OA was developed in collaboration with orthopedic surgeons with extensive research experience and methodological expertise. The ...
Ratcliffe Matthew - - 2013
This paper seeks to illuminate the nature of empathy by reflecting upon the phenomenology of depression. I propose that depression involves alteration of an aspect of experience that is seldom reflected upon or discussed, thus making it hard to understand. This alteration involves impairment or loss of a capacity for ...
Jin An - - 2013
Three new alkaloids, 2α-hydroxy-6-O-n-butyloduline, O-n-butyllycorenine, (-)-N-(chloromethyl)lycoramine (1-3), and a new phenolic compound, ((7S)-7-(4-hydroxyphenyl)-7-hydroxypropyl)-2'-methylbenzene-3',6'-diol (14), along with ten known alkaloids (4-13), were isolated from the bulbs of Lycoris aurea collected from Huaihua County of Hunan Province, China. Their structures were elucidated by spectroscopic methods including HRESIMS, UV, IR, and NMR. All ...
Wei Yumeng - - 2013
In order to develop a novel lung targeting drug delivery system (LTDDS) with large-sized liposomes containing paclitaxel (PTX), the liposomes composed of PTX, phosopholipon 90H and tween-80 were prepared by the effervescent dispersion technique with optimal formulation composition. The liposomes were found to be relatively uniform in particle size (8.166 ± 0.459 μm) ...
Kim Nam Ah - - 2013
To investigate the effects of polymeric excipients for dutasteride solid dispersion, experimental approaches together with physical interactions at molecular level were evaluated. The drug and various polymers (anionic, amphiphilic, and hydrophilic) were mixed physically into different ratios and their thermodynamic and physical properties were analyzed by differential scanning calorimetry and ...
Stepanova Maria - - 2013
AIM: Non-alcoholic steatohepatitis (NASH) patients are at increased risk for progression to cirrhosis. The aim of this study was to assess all-cause and liver-specific mortality in a cohort of non-alcoholic fatty liver disease (NAFLD) patients. METHODS: Biopsy-proven NAFLD patients with and without NASH from two historic databases were included. Clinico-demographic ...
Drličková Gabriela - - 2013
The growth of maize (Zea mays L.), hybrid Valentina, was compared in two types of contaminated soil substrates (Ochre and Heap) with different arsenic (As) concentration originating from an old mining area in Slovakia. Although the total As concentration in Heap soil was 2.6 times lower than in Ochre soil ...
Guo Qiang - - 2013
To understand the role of silicon (Si) in alleviating sodium (Na) toxicity in Trifolium repens L. (white clover), the changes of biochemical and physiological parameters were investigated in four-week-old white clover seedlings exposed to 0 or 120 mM NaCl with or without 1.5 mM Si for 7 days. Results showed that added Si ...
Watanabe Yoshinobu - - 2013
BACKGROUND: If some predictable factors that affect the treatment results of low-intensity pulsed ultrasound (LIPUS) for delayed union or nonunion could be determined, these might provide us with suggestions for whether LIPUS should be used as an alternative treatment for surgery or an adjuvant therapy after surgery. Therefore, the objective ...
Du Yan - - 2013
Located in Central South China, Hunan province is rich in mineral resources. To study the influence of mining on Cd pollution to local agricultural eco-system, the paddy soils and rice grain of Y county in northern Hunan province were intensively monitored. The results were as follows: (1) Total Cd (T-Cd) ...
Romano Ariel - - 2013
While there has been extensive interest in the use of boron isotope ratios as a surrogate of pH in paleoclimate studies in the context of climate change-related questions, the high (0.4 mM) concentration and the depth-independent (conservative or non-nutrient-like) concentration profile of this element have led to boron being neglected ...
Kim Hak Soo - - 2013
PURPOSE: Nitric oxide (NO), a short-lived gaseous free radical, is a potent mediator of biological responses involved in the pathogenesis of autoimmune rheumatic diseases, such as systemic lupus erythematosus (SLE) and rheumatoid arthritis (RA). Nitric oxide also serves as an important signal in physiological processes, including angiogenesis, thrombosis, and bone ...
Terabe Mitsuaki - - 2013
We investigated artifacts due to late-arriving contrast medium (CM) during C-arm cone-beam computed tomography. We scanned a phantom filled with water or with 100, 50, or 5 % v/v concentrations of CM and then virtually produced CM-delayed projection data by partially replacing the projection images. Artifacts as a function of concentration, ...
Sorensen Jesper Roed - - 2013
In 2007, a fast track program for patients with suspicion of head and neck cancer (HNC) was introduced in Denmark to reduce unnecessary waiting time. The program was based on so called "package solutions" including pre-booked slots for outpatient evaluation, imaging, and diagnostic surgical procedures. The purpose of this study ...
Sethi Roshan - - 2013
OBJECTIVES/HYPOTHESIS: To review the known histopathologic findings and clinical behavior of mammary analogue secretory carcinoma (MASC). DATA SOURCES: PubMed. REVIEW METHODS: Literature search using the terms "Mammary analogue secretory carcinoma," "Mammary analog secretory carcinoma," and "MASC" to identify all relevant publications. RESULTS: MASC is an unusual and rare malignant salivary ...
Tan Angel - - 2013
The diversity of lipid excipients available commercially has enabled versatile formulation design of lipid-based drug delivery systems for enhancing the oral absorption of poorly water-soluble drugs, such as emulsions, microemulsions, micelles, liposomes, niosomes and various self-emulsifying systems. The transformation of liquid lipid-based systems into solid dosage forms has been investigated ...
Zhang Zhengfeng - - 2013
PURPOSE: To identify anterior spinal artery (ASA) infarct or occlusion by CT angiography (CTA) in patients with cervical spondylotic myelopathy (CSM). METHODS: Fourteen patients with CSM were performed CTA of ASA after admission. T2-weighted hyperintensity of MR image was compared with image of CTA of ASA. RESULTS: All patients presented ...
Ma Weihu - - 2013
STUDY DESIGN: A retrospective study was conducted to evaluate anterior plate fixation of unstable atlas fractures using a transoral approach. OBJECTIVE: To further investigate the safety and efficacy of this surgical technique, as there is currently a paucity of available data. While most atlas fractures can be managed by external ...
Wagner David W - - 2013
Musculoskeletal simulation software and model repositories have broadened the user base able to perform musculoskeletal analysis and have facilitated in the sharing of models. As the recognition of musculoskeletal modeling continues to grow as an engineering discipline, the consistency in results derived from different models and software is becoming more ...
Li Juan - - 2013
Ascorbic acid (AsA) plays an essential role in plants by protecting cells against oxidative damage. GDP-L-galactose phosphorylase (GGP) is the first committed gene for AsA synthesis. Our research examined AsA levels, regulation of GGP gene expression, and how these are related to abiotic stresses in two species of Actinidia (kiwifruit). ...
Miwa Toshitada - - 2013
PURPOSE: Adjacent segment disease (ASD) is an increasing problematic complication following lumbar fusion surgeries. ASD requires appropriate treatment, although there are only few reports on surgery for ASD. This study aimed to clarify surgical outcomes of posterior lumbar interbody fusion (PLIF) for ASD. METHODS: Medical charts of 18 patients who ...
Nakazawa Yoshihisa - - 2013
A microscopic technique combining spectral confocal laser scanning microscopy with a lipophilic fluorescent dye, Nile red, which can emit trans-polyisoprene specific fluorescence, was developed, and unmixed images of synthesized trans-polyisoprene in situ in Eucommia ulmoides were successfully obtained. The images showed that trans-polyisoprene was initially synthesized as granules in non-articulated ...
de Los Milagros Bassani Molinas Maria - - 2013
Large scale, transient gene expression (TGE) is highly dependent of the physiological status of a cell line. Therefore, intracellular nucleotide pools and ratios were used for identifying and monitoring the optimal status of a suspension cell line used for TGE. The transfection efficiency upon polyethyleneimine (PEI)-mediated transient gene delivery into ...
Kaiser Frank - - 2013
Human peripheral blood monocytes were exposed to single or pairs of cell stress proteins (CSPs), specifically Hsp10, Hsp27, Hsp60 and Hsp70-the former two having anti-inflammatory actions while the latter pair being assumed to be pro-inflammatory in activity. This study was to test if these proteins exhibited any network behaviour. To ...
Doku Reginald T - - 2013
Cu(I) exhibits high affinity for thiolate ligands, suggesting that thiol-rich zinc or iron binding sites may be subject to disruption during copper stress conditions. Zinc fingers constitute a large class of metalloproteins that use a combination of cysteine and histidine residues that bind Zn(II) as a structural element. Despite the ...
Fritzell Sara - - 2013
Despite temozolomide (TMZ) treatment, the prognosis for patients with glioblastoma multiforme is still dismal. As dose escalation of TMZ is limited by systemic toxicity, intratumoral delivery emerges as an attractive treatment modality, which may sustain cytotoxic drug concentrations intratumorally and induce immunogenic cell death. Both clinical and experimental gliomas have ...
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