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Arbuckle Tye E - - 2013
The Maternal-Infant Research on Environmental Chemicals (MIREC) Study was established to obtain Canadian biomonitoring data for pregnant women and their infants, and to examine potential adverse health effects of prenatal exposure to priority environmental chemicals on pregnancy and infant health. Women were recruited during the first trimester from 10 sites ...
Zagouri Flora - - 2013
Pancreatic cancer is the fourth leading cause of cancer-related death. Most patients present with an advanced stage of disease that has a dismal outcome, with a median survival of approximately 6 months. Evidently, there is a clear need for the development of new agents with novel mechanisms of action in ...
Wang Jing - - 2013
We investigated whether pancreatitis-associated ascitic fluid (PAAF) could induce the expression of tumor necrosis factor α (TNF-α) and interleukin 6 (IL-6) in THP-1 cells and the mechanism(s) involved. THP-1 cells were divided into control and PAAF groups. The PAAF group was incubated with different final concentrations of PAAF, whereas the ...
Voslarova E - - 2013
The physiological changes in response to beak trimming and spectacle usage as antipecking measures were monitored in 10-mo-old common pheasants (Phasianus colchicus). Short-term analysis conducted before the beginning of the laying period showed immediate increases of plasma corticosterone (P < 0.05) and lactate dehydrogenase (P < 0.001) concentrations and decrease ...
Wang C - - 2013
One approach for cost-effective implementation of genomic selection is to genotype training individuals with a high-density (HD) panel and selection candidates with an evenly spaced, low-density (ELD) panel. The purpose of this study was to evaluate the extent to which the ELD approach reduces the accuracy of genomic estimated breeding ...
Narinc Dogan - - 2013
The aim of this study was to evaluate the genetic parameters of several breast meat quality traits and their genetic relationships with some slaughter traits [BW, breast yield (BRY), and abdominal fat yield (AFY)]. In total, 1,093 pedigreed quail were slaughtered at 35 d of age to measure BRY, AFY, ...
Jin Sihua - - 2013
Growth and feeding traits such as BW, BW gain (BWG), feed intake (FI), and feed conversion ratio (FCR) are of economic importance in poultry production. In this study, 8 SNP of the transforming growth factor β3 (TGF-β3) gene, which are located in the proximity of quantitative trait loci affecting BW ...
Yin Guangwen - - 2013
The enzyme-linked immunosorbent spot (ELISPOT) assay is a sensitive and easy-to-use tool to quantify the number of interferon (IFN)-γ-producing cells and offers a viable alternative for the quantitative measurement of T cell functions in chickens. To study the development of cell-mediated immunity in Eimeria-infected chickens, we measured the number of ...
Shao Yujing - - 2013
This study investigated the protective effect of β-1,3/1,6-glucan on gut morphology, intestinal epithelial tight junctions, and bacterial translocation of broiler chickens challenged with Salmonella enterica serovar Typhimurium. Ninety Salmonella-free Arbor Acre male broiler chickens were randomly divided into 3 groups: negative control group (NC), Salmonella Typhimurium-infected positive group (PC), and ...
Abd El-Wahab A - - 2013
Foot pad dermatitis (FPD) is a widespread problem in poultry production and constitutes a welfare issue. The objective of this study was to test potentially prophylactic effects of higher biotin and Zn levels in the diet of broilers exposed to critical litter moisture content (35% water) on the development of ...
Cha S-Y - - 2013
Egg drop syndrome virus (EDSV) is an important pathogen of poultry that decreases egg production in chickens and causes respiratory disease in goslings. In 2011, we obtained serum samples from 139 domestic Pekin ducks, 416 one-day-old Pekin ducklings, and 75 wild ducks (67 mallards and 8 pintails) to survey their ...
Zhang S J - - 2013
This experiment was conducted to study the digestibility of uncommon feedstuffs for geese. Thirty Taihu ganders were selected and divided into 5 groups (n = 6), and one group was allocated as the control. Taihu ganders in the 4 treated groups were force-fed with a weight of different uncommon feedstuffs ...
Karimi A - - 2013
A total of 735 one-day-old male broiler chicks were used to evaluate the interactions between different levels of phytase and xylanase enzymes on performance and bone mineralization. Basal nonphytate P (nPP)-deficient diets (0.15%) were supplemented with different levels of phytase [0X, 1X, 2X, 3X, and 4X of recommended level (X ...
Zhai Q H - - 2013
A total of five hundred forty 19-wk-old HyLine Brown hens were used to study the long-term effects of increasing choline with 0 (control), 425, 850, 1,700, 3,400, and 6,800 mg/kg of corn-soybean meal-based diets on productive performance and egg quality. Phase 1 was from 19 to 58 wk, and phase ...
Chen Xi - - 2013
The nutritional values of a novel reduced-oligosaccharide soybean meal (SBM-RO) and conventional SBM (SBM-CV) were evaluated and compared in 4 experiments. The first experiment was a TMEn assay with conventional roosters. The second experiment was a precision-fed cecectomized rooster assay that was conducted to determine TMEn and amino acid (AA) ...
Farahat M H - - 2013
Phytase was examined as a means to improve turkey performance in diets with high Cl by modifying dietary electrolyte balance. Nicholas turkey toms (10 poults/pen; 10 replicates per pen) were fed corn-soy-distillers dried grains with solubles-canola meal-based diets (DDGS/CM) with varying Cl (0.2, 0.3, 0.4, or 0.5%) and phytase (0 ...
Frikha M - - 2013
The effects of autoclaving 2 varieties of micronized (fine grinding) pea protein concentrate (PPC) on the ileal digestibility (ID) of CP and amino acids (AA) were studied in broilers. There was a control diet based on fermented soybean meal (FSBM) and 4 extra diets in which the FSBM was substituted ...
Gehring C K - - 2013
The objective was to determine the effects of extractable salt-soluble protein content of corn (PS) and exogenous enzyme supplementation on N, starch, and energy digestibility in broilers fed diets adequate in Ca and nonphytate P. Broilers were randomly distributed into floor pens (6 replicate pens per treatment) with 28 birds ...
Choi Y M - - 2013
The aim of this study was to investigate the DNA content and morphological characteristics of muscle fibers, and their relation to the growth performance in random bred control (RBC) and heavy weight (HW) Japanese quail lines. The 2 lines were of similar embryo size at 6 and 8 d of ...
Yu S L - - 2013
The CCAAT/enhancer-binding protein β gene (C/EBPβ) is one of the key regulating factors of lipid metabolic balance in the liver. To better understand how C/EBPβ affects lipid accumulation in the Landes goose liver, its DNA was cloned. The goose C/EBPβ DNA sequence (2,075 bp) contains a 984-bp open reading frame ...
Willems E - - 2013
To examine the importance of albumen as a protein source during embryonic development on the posthatch performance of laying hens, 3 mL of the albumen was removed. At hatch, no difference in BW could be observed. Chicks from the albumen-deprived group had a lower residual yolk weight due to higher ...
Silversides F G - - 2013
Avian genetic resources have declined dramatically over the past half century, partly because the poultry community has been slow to adopt cryoconservation of avian germplasm. Techniques for gonadal cryopreservation and functional recovery have recently been developed but only some have been optimized. Chicks were castrated at 2 or 6 d ...
Fujisawa N - - 2013
A 1,000-fold difference has been reported in dioxin sensitivity between avian species. This difference is because the 2 amino acids in the type 1 aryl hydrocarbon receptor (AhR1), at positions 325 and 381, correspond to Leu324 and Ser380 in chickens. The chicken had been reported to be the only avian ...
Fabrizio Cecilia S - - 2013
There is a dearth of high-level evidence for brief programs designed to promote positive parent-child relationships in nonwestern cultures. We present a pilot randomized controlled trial of a four-session intervention to enhance the parenting skills that promote a positive relationship with pre-adolescent children in Hong Kong. Our intervention, Harmony@Home, utilized ...
Cotte Laurent - - 2013
OBJECTIVE:: To investigate the safety, tolerability, pharmacokinetics, and antiviral activity of BMS-986001 (a nucleoside reverse transcriptase inhibitor) in treatment-experienced, HIV-1-infected subjects not exposed to antiretroviral treatment in the previous 3 months. METHODS:: Thirty-two HIV-1-infected subjects were randomized (3:1) to receive BMS-986001 or placebo once daily for 10 days in this ...
van Geenen Erwin-Jan M - - 2013
OBJECTIVES: Several randomized controlled trials studied the role of endoscopic retrograde cholangiopancreaticography (ERCP) and endoscopic sphincterotomy (ES) in acute biliary pancreatitis (ABP). No study assessed whether these trials resulted in international consensus in published meta-analyses and treatment guidelines. METHODS: A systematic review, according to the Preferred Reporting Items for Systematic ...
Engels Paul T - - 2013
OBJECTIVES:: To 1) review the existing evidence for early mobilization of the critically ill patients in the ICU with polytrauma; 2) provide intensivists with an introduction to the biomechanics, physiology, and nomenclature of injuries; 3) summarize the evidence for early mobilization in each anatomic area; and 4) provide recommendations for ...
Redford Melissa A - - 2013
The goals of the current study were (1) to assess differences in child and adult pausing, and (2) to determine whether characteristics of child and adult pausing can be explained by the same language variables. Spontaneous speech samples were obtained from ten 5-year-olds and their accompanying parent using a storytelling/retelling ...
Avila K A - - 2013
PURPOSE: Mucoceles are cystic lesions, resulting from an obstruction in the paranasal sinuses and an accumulation of mucus, causing enlargement of the affected paranasal sinus. The signs and symptoms depend on the affected sinus. Treatment consists of surgical resection. The purpose of this study was to describe the clinical presentation ...
Sender M J - - 2013
OBJETIVE: To screen for eye disease in diabetic patients by performing only an eye fundus examination with non-mydriatic retinography, or a more extensive ophthalmological examination including visual acuity (VA) and ocular tonometry. MATERIAL AND METHODS: Design: A cross-sectional multicentre study with cohort comparison. Subjects: Diabetic patients who attended 6 Primary ...
Niho Seiji - - 2013
INTRODUCTION:: We conducted a phase II study of combination chemotherapy with irinotecan (CPT) and cisplatin (CDDP) in patients with advanced large-cell neuroendocrine carcinoma (LCNEC) of the lung. METHODS:: Patients received irinotecan (60 mg/m, days 1, 8, and 15) and cisplatin (60 mg/m, day 1) every 4 weeks for up to ...
Kulpa Deanna A - - 2013
A major challenge in the development of a cure for human immunodeficiency virus (HIV) has been the incomplete understanding of the basic mechanisms underlying HIV persistence during antiretroviral therapy. It is now realized that the establishment of a latently infected reservoir refractory to immune system recognition has thus far hindered ...
Charlesworth Amanda - - 2013
Poly(A) tail elongation after export of an messenger RNA (mRNA) to the cytoplasm is called cytoplasmic polyadenylation. It was first discovered in oocytes and embryos, where it has roles in meiosis and development. In recent years, however, has been implicated in many other processes, including synaptic plasticity and mitosis. This ...
Huang Hsu-Ching HC Department of Chest Medicine, Taipei Veterans General Hospital, Taipei, - - 2013
Lung cancer with breast metastasis is rare. However, differentiating between primary breast cancer and metastatic lung adenocarcinoma is of clinical importance. The metastasis cascade of how cancer cells migrate from the primary lung tumor to the breast is not clear yet. Pathology and cytology databases were searched for patients diagnosed ...
Fan Wei W Center of Reproductive Medicine, The West China Second University Hospital, Sichuan University, Sichuan, People's Republic of China. - - 2013
Human sex hormone-binding globulin (SHBG) is a specific plasma transport glycoprotein for sex steroid hormones, and serum SHBG levels were decreased in polycystic ovary syndrome (PCOS) patients. To clarify the conflicting data in the literature concerning the association between PCOS and the (TAAAA)n SHBG polymorphism, and influence of the (TAAAA)n ...
Stephenson Kathryn E KE Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Boston, MA, - - 2013
A global human immunodeficiency virus-1 (HIV-1) vaccine will have to elicit immune responses capable of providing protection against a tremendous diversity of HIV-1 variants. In this review, we first describe the current state of the HIV-1 vaccine field, outlining the immune responses that are desired in a global HIV-1 vaccine. ...
Marik Paul E PE Division of Pulmonary and Critical Care Medicine, Eastern Virginia Medical School, Norfolk, VA, USA. - - 2013
Despite a previous meta-analysis that concluded that central venous pressure should not be used to make clinical decisions regarding fluid management, central venous pressure continues to be recommended for this purpose. To perform an updated meta-analysis incorporating recent studies that investigated indices predictive of fluid responsiveness. A priori subgroup analysis ...
Teperman Lewis L Mary Lea Johnson Richards Organ Transplant Center, New York University School of Medicine, New York, NY 10016, USA. - - 2013
Mycophenolate mofetil (MMF) and sirolimus (SRL) have been used for calcineurin inhibitor (CNI) minimization to reduce nephrotoxicity following liver transplantation. In this prospective, open-label, multicenter study, patients undergoing transplantation from July 2005 to June 2007 who were maintained on MMF/CNI were randomized 4 to 12 weeks after transplantation to receive ...
Warshak Carri R CR Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, University of Cincinnati College of Medicine, OH 45267-0526, - - 2013
We hypothesise that the rate of stillbirth is increased in mothers younger than 18 years of age compared to adult mothers, and that obesity further increases the risk of stillbirth in this population. We conducted a population-based cohort study comparing rates of stillbirth between adolescent, defined as young women under ...
Kejner Alexandra E AE Department of Otolaryngology, University of Alabama-Birmingham, Birmingham, Alabama, - - 2013
To evaluate bone invasion, survival, and expression of bone morphogenetic protein-6 (BMP-6) in oral cavity cancer in the context of known biomarkers indicative of poor prognosis. Molecular expression study combined with retrospective chart review of corresponding patients at a tertiary care center. Between 2000 and 2009, a total of 197 ...
Larsen Pernille Stemann PS Section of Social Medicine, Department of Public Health, University of Copenhagen, Copenhagen. - - 2013
During the past 25 years, many pregnancy and birth cohorts have been established. Each cohort provides unique opportunities for examining associations of early-life exposures with child development and health. However, to fully exploit the large amount of available resources and to facilitate cross-cohort collaboration, it is necessary to have accessible ...
Hunter Gary R GR Department of Human Studies, University of Alabama at Birmingham, AL 35294-1250, USA. - - 2013
To examine the effects of three different frequencies of combined resistance and aerobic training on total energy expenditure (TEE) and activity-related energy expenditure (AEE) in a group of older adults. Seventy-two women, 60-74 yr old, were randomly assigned to one of three groups: 1 d · wk(-1) of aerobic training ...
Xu Huanbin H Tulane National Primate Research Center, Tulane University School of Medicine, Covington, LA 70433, - - 2013
Recent advances in the immunology, pathogenesis, and prevention of human immunodeficiency virus (HIV) infection continue to reveal clues to the mechanisms involved in the progressive immunodeficiency attributed to infection, but more importantly have shed light on the correlates of immunity to infection and disease progression. HIV selectively infects, eliminates, and/or ...
Okoye Afam A AA Vaccine and Gene Therapy Institute and Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR 97006, USA. - - 2013
The hallmark of acquired immunodeficiency syndrome (AIDS) pathogenesis is a progressive depletion of CD4(+) T-cell populations in close association with progressive impairment of cellular immunity and increasing susceptibility to opportunistic infections (OI). Disease progression in untreated human immunodeficiency virus (HIV) infection can take many years, and it was originally hypothesized ...
Paiardini Mirko M Division of Microbiology and Immunology, Yerkes National Primate Research Center, and Department of Pathology and Laboratory Medicine, Emory University, Atlanta, GA 30329, USA. - - 2013
Systemic chronic immune activation is considered today as the driving force of CD4(+) T-cell depletion and acquired immunodeficiency syndrome (AIDS). A residual chronic immune activation persists even in HIV-infected patients in which viral replication is successfully inhibited by anti-retroviral therapy, with the extent of this residual immune activation being associated ...
Burdo Tricia H TH Department of Biology, Boston College, Chestnut Hill, MA 02467, - - 2013
Neurological sequelae of human immunodeficiency virus (HIV) infection have been and remain a significant problem. Monocytes and macrophages in humans and monkeys are susceptible to infection by HIV and simian immunodeficiency virus (SIV), and are considered to be a main mechanism by which the central nervous system (CNS) is infected. ...
Chang Christina C CC Department of Infectious Diseases, Alfred Hospital and Monash University, Melbourne, - - 2013
Despite significant reductions in morbidity and mortality secondary to availability of effective combination anti-retroviral therapy (cART), human immunodeficiency virus (HIV) infection still accounts for 1.5 million deaths annually. The majority of deaths occur in sub-Saharan Africa where rates of opportunistic co-infections are disproportionately high. In this review, we discuss the ...
Demers Korey R KR Department of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, - - 2013
A detailed understanding of the immune response to human immunodeficiency virus (HIV) infection is needed to inform prevention and therapeutic strategies that aim to contain the acquired immunodeficiency syndrome (AIDS) pandemic. The cellular immune response plays a critical role in controlling viral replication during HIV infection and will likely need ...
Klatt Nichole R NR Department of Pharmaceutics, Washington National Primate Research Center, University of Washington, Seattle, WA, - - 2013
Despite complete or near-complete suppression of human immunodeficiency virus (HIV) replication with combination antiretroviral therapy, both HIV and chronic inflammation/immune dysfunction persist indefinitely. Untangling the association between the virus and the host immune environment during therapy might lead to novel interventions aimed at either curing the infection or preventing the ...
Nelson Peter T PT Sanders Brown Center on Aging, University of Kentucky, Lexington, Kentucky, - - 2013
The APOE-ε4 allele correlates with increased risk of Alzheimer disease (AD) and increased parenchymal amyloid plaques. We tested how the APOE genotype correlated with cerebral amyloid angiopathy (CAA) by analyzing 371 brains for parenchymal and meningeal CAA in 4 brain regions (frontal, parietal, temporal, and occipital neocortex). The overall severity ...
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