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Results 501 - 550 of 6819
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Kim Nam Ah - - 2013
To investigate the effects of polymeric excipients for dutasteride solid dispersion, experimental approaches together with physical interactions at molecular level were evaluated. The drug and various polymers (anionic, amphiphilic, and hydrophilic) were mixed physically into different ratios and their thermodynamic and physical properties were analyzed by differential scanning calorimetry and ...
Tucker Edmonds Brownsyne - - 2013
To determine predictors and pregnancy outcomes associated with antepartum discharge against medical advice (AMA D/C). Retrospective cohort study of state-level maternal and infant hospital discharge data linked to vital statistics data for antepartum admissions in California from 1995 to 2005. (N = 203,250). After adjusting for comorbid conditions, the odds of AMA ...
Du Liutao L Department of Pathology and Laboratory Medicine, The David Geffen School of Medicine at UCLA, Los Angeles, CA, USA. - - 2013
Chemical-induced read through of premature stop codons might be exploited as a potential treatment strategy for genetic disorders caused by nonsense mutations. Despite the promise of this approach, only a few read-through compounds (RTCs) have been discovered to date. These include aminoglycosides (e.g., gentamicin and G418) and nonaminoglycosides (e.g., PTC124 ...
Saneei Parvane - - 2013
The effects of the Dietary Approaches to Stop Hypertension (DASH) eating plan on childhood metabolic syndrome (MetS) and insulin resistance remain to be determined. The present study aimed to assess the effects of recommendations to follow the DASH diet v. usual dietary advice (UDA) on the MetS and its features ...
Sun Ke - - 2013
3D interdigitated microbattery architectures (3D-IMA) are fabricated by printing concentrated lithium oxide-based inks. The microbatteries are composed of interdigitated, high-aspect ratio cathode and anode structures. Our 3D-IMA, which exhibit high areal energy and power densities, may find potential application in autonomously powered microdevices.
Laccourreye Ollivier - - 2013
OBJECTIVES/HYPOTHESIS: To analyze local failure following lateral pharyngotomy for selected untreated invasive squamous cell carcinoma (SCC) of the lateral oropharynx. STUDY DESIGN: Retrospective review from a university teaching hospital. METHODS: Inception cohort of 91 patients who underwent lateral pharyngotomy for an isolated and previously untreated selected invasive carcinoma of the ...
Formisano Carmen - - 2013
The hydrodistillation of the aerial parts of Nepeta cilicica Boiss. ex Benth., collected in Lebanon in the Horsh Ehden reserve, yielded 0.13% (w/w) of essential oil. Gas chromatography (GC) and GC-mass spectroscopy analysis enabled the identification of 75 compounds representing 96.8% of the total oil. The most abundant compounds were ...
Leemreis Willem H - - 2013
Studies indicate serious levels of stress among parents of children with a medical condition. Moreover, adaptation seems to be a specific challenge for parents of children with a disfiguring condition because of the visible nature of the condition. In the present overview, we performed a literature search in PubMed, Embase, ...
Griffith Rachel M RM Department of Ophthalmology, Boston Children's Hospital, 300 Longwood Avenue, Fegan 4, Boston, MA 02115, - - 2013
The purpose of this study was to identify the genes, biochemical signaling pathways, and biological themes involved in the pathogenesis of retinopathy of prematurity (ROP). Next-generation sequencing (NGS) was performed on the RNA transcriptome of rats with the Penn et al. (Pediatr Res 36:724-731, 1994) oxygen-induced retinopathy model of ROP ...
Jiang Guangming - - 2013
Recent studies have shown that free nitrous acid (FNA) is biocidal to a broad range of microorganisms. Microorganisms residing in anaerobic sewer biofilms were found to be inactivated after a short (6-24 h) exposure to FNA. In this study, we investigate the inactivation kinetics of anaerobic sewer biofilms grown in real ...
Chang Peter Mu-Hsin - - 2013
BACKGROUND: Non-small cell lung cancer (NSCLC) is the leading cause of cancer deaths around the world, and a high recurrence rate after complete resection is an important issue reducing the cure rate and survival of patients with early stage NSCLC. Several pathologic biomarkers are associated with recurrence in early stage ...
Rasmussen M M - - 2013
Study design:Clinical study.Objectives:To explore how supraconal spinal cord injury (SCI) affects colorectal emptying at defecation. Further, to relate findings to subject symptomatology expressed by bowel function scores and gastrointestinal transit time (GITT).Setting:Aarhus University Hospital, Denmark.Methods:Colorectal contents were marked by oral intake of (111)In-coated resin pellets. Movement of stools at defecation ...
Kometani Takuro T Department of Thoracic Surgery, Graduate School of Medicine, Chiba University, Chiba, Japan. - - 2013
Postoperative acute respiratory distress syndrome (ARDS) is a recognized complication of pulmonary resection. It is characterized by the acute onset of hypoxemia with radiographic infiltrates consistent with pulmonary edema, without elevations in the pulmonary capillary wedge pressure. Many studies suggest that around 2-5 % of patients develop some degree of lung ...
Dhooria Gurdeep Singh - - 2013
Patients with renal tubular acidosis (RTA) usually have tubular or low molecular weight proteinuria. The authors present a rare case of a 6-y-old girl with Fanconi syndrome secondary to cystinosis, who at presentation had nephrotic range proteinuria along with rickets and failure to thrive. Although hypoalbuminemia and massive proteinuria are ...
Warth Benedikt - - 2013
Mycotoxins are toxic fungal secondary metabolites that frequently contaminate food and feed worldwide, and hence represent a major hazard for food and feed safety. To estimate human exposure arising from contaminated food, so-called biomarker approaches have been developed as a complementary biomonitoring tool besides traditional food analysis. The first methods ...
Di Martino A A Phyllis Green and Randolph Cowen Institute for Pediatric Neuroscience at the NYU Child Study Center, New York University Langone Medical Center, New York, NY, - - 2014
Autism spectrum disorders (ASDs) represent a formidable challenge for psychiatry and neuroscience because of their high prevalence, lifelong nature, complexity and substantial heterogeneity. Facing these obstacles requires large-scale multidisciplinary efforts. Although the field of genetics has pioneered data sharing for these reasons, neuroimaging had not kept pace. In response, we ...
Wu Qi - - 2013
To compare the values of endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) and TBNA for the diagnosis of hilar and mediastinal lesions. The clinical data of 100 patients who underwent EBUS-TBNA (n=50) and TBNA (n=50) between January 2010 and May 2011 were retrospectively reviewed, and the results and complications were recorded. ...
Renard V T - - 2013
The fundamental properties of valleys are recently attracting growing attention due to electrons in new and topical materials possessing this degree-of-freedom and recent proposals for valleytronics devices. In silicon MOSFETs, the interest has a longer history since the valley degree of freedom had been identified as a key parameter in ...
Hoekman Peter K - - 2013
OBJECTIVES/HYPOTHESIS: To report the utilization and cost effectiveness of magnetic resonance imaging (MRI) in the evaluation of patients with idiopathic olfactory loss. STUDY DESIGN: Case series with chart review. METHODS: A retrospective review of patients presenting with olfactory disorders at a university-based taste and smell center from July 1998 through ...
Aigner F - - 2013
PURPOSE: The aim of this study was to compare postoperative pain between the open tension-free plug and patch (PP) technique and the totally extraperitoneal patch (TEP) hernioplasty. METHODS: One hundred and fifty-four male patients with unilateral inguinal hernia were randomized to undergo PP and TEP from 2005 to 2009. Pain ...
Schmieder Phillip - - 2013
The novel homochiral metal-organic framework CFA-1 (Coordination Framework Augsburg-1), [Zn5(OAc)4(bibta)3], containing the achiral linker {H2-bibta = 1H,1'H-5,5'-bibenzo[d][1,2,3]triazole}, has been synthesised. The reaction of H2-bibta and Zn(OAc)2·2H2O in N-methylformamide (NMF) (90 °C, 3 d) yields CFA-1 as trigonal prismatic single crystals. CFA-1 serves as a convenient precursor for the synthesis of ...
Stepanova Maria - - 2013
AIM: Non-alcoholic steatohepatitis (NASH) patients are at increased risk for progression to cirrhosis. The aim of this study was to assess all-cause and liver-specific mortality in a cohort of non-alcoholic fatty liver disease (NAFLD) patients. METHODS: Biopsy-proven NAFLD patients with and without NASH from two historic databases were included. Clinico-demographic ...
Mitin Alexander V - - 2013
The 2df polarization functions for the modified m6-31G basis sets of the third-row atoms Ga through Kr (Int J Quantum Chem, 2007, 107, 3028; Int J. Quantum Chem, 2009, 109, 1158) are proposed. The performances of the m6-31G, m6-31G(d,p), and m6-31G(2df,p) basis sets were examined in molecular calculations carried out ...
Németh Péter - - 2013
New methods for defect analysis can lead to improved interpretation of experimental data and thus better understanding of material properties. Although transmission electron microscopy (TEM) has been used to study defects for many decades, interpretive ambiguities can arise for cases that seem simple or even trivial. Using geometric phase analysis ...
Neumann William L - - 2013
Autoimmune gastritis is a chronic progressive inflammatory condition that results in the replacement of the parietal cell mass by atrophic and metaplastic mucosa. A complex interaction of autoantibodies against the parietal cell proton pump and sensitized T cells progressively destroy the parietal cells, inducing hypochlorhydria and then achlorhydria, while autoantibodies ...
Meyer K M - - 2013
A 41-year-old man presented at our clinic with several bluish to purple nodular plaques (measuring 2 to 3 cm in diameter) on the upper chest (Fig. 1a; arrows) and the back. The lesions had existed for approximately 8 years without causing any symptoms. Three years ago, disseminated brown-reddish macules had ...
Raphael Jean L JL Department of Pediatrics, Baylor College of Medicine, Houston, - - 2013
Blood transfusions represent a major therapeutic option in acute management of sickle cell disease (SCD). Few data exist documenting trends in transfusion among children with SCD, particularly during hospitalization. This was an analysis of cross-sectional data of hospital discharges within the Kid's Inpatient Database (years 1997, 2000, 2003, 2006, 2009). ...
Sørensen Sr - - 2013
European eel, Anguilla anguilla, is a target species for future captive breeding, yet best methodology to estimate sperm density for application in in vitro fertilization is not established. Thus, our objectives were to evaluate methods to estimate European eel sperm density including spermatocrit, computer-assisted sperm analysis (CASA) and flow cytometry ...
Lee King Chien Joe - - 2013
To provide a critical contemporary review of daily PDE5-inhibitor (PDE5-I) use in urological and nonurological conditions. PDE5-Is can be taken up to once a day. However, at present only tadalafil is approved for use in both erectile dysfunction (ED) and benign prostate hyperplasia (BPH) with lower urinary tract symptoms (LUTS). ...
Terabe Mitsuaki - - 2013
We investigated artifacts due to late-arriving contrast medium (CM) during C-arm cone-beam computed tomography. We scanned a phantom filled with water or with 100, 50, or 5 % v/v concentrations of CM and then virtually produced CM-delayed projection data by partially replacing the projection images. Artifacts as a function of concentration, ...
Sullivan Steve - - 2013
The history of the relationship between religion and mental health is one of commonality, conflict, controversy, and distrust. An awareness of this complex relationship is essential to clinicians and clergy seeking to holistically meet the needs of people in our clinics, our churches, and our communities. Understanding this relationship may ...
Chae Hyun Wook - - 2013
PURPOSE: Medulloblastoma is a highly malignant childhood brain tumor. Survival from medulloblastoma is increasing. This study was performed to examine growth outcomes, insulin-like growth factor-1(IGF-1), and response to growth hormone (GH) treatment in children with medulloblastoma. METHODS: Retrospective analysis of 34 children treated with GH for medulloblastoma was performed. We ...
Zhao Wei-Xin - - 2013
This study aims to evaluate the association of serum neuron-specific enolase (NSE) levels with the prognosis of small cell lung cancer (SCLC). Literature retrieval, trials selection and assessment, data collection, and statistical analysis were performed according to the Revman 5.0 guidelines. Literature-based searching was guided to gather data and either ...
Ciccacci Cinzia - - 2013
PURPOSE: Nevirapine (NVP) is a non-nucleoside reverse transcriptase inhibitor, widely prescribed for type 1 human immunodeficiency virus infection. A small proportion of individuals treated with NVP experience severe cutaneous adverse events, including Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN). Our aim was to verify whether genetic variability in NVP-metabolizing ...
Agnusdei V - - 2013
T acute lymphoblastic leukemia (T-ALL) is characterized by several genetic alterations and poor prognosis in about 20-25% of patients. Notably, about 60% of T-ALL shows increased Notch1 activity, due to activating NOTCH1 mutations, or alterations in the FBW7 gene, which confer to the cell a strong growth advantage. Therapeutic targeting ...
Sherafat-Kazemzadeh R - - 2013
BACKGROUND: The importance of hyperphagia as a cause for energy imbalance in humans with Bardet-Biedl syndrome (BBS) has not been established. We therefore compared hyperphagic symptoms in patients with BBS vs. controls. METHODS: : We studied 13 patients with BBS and 23 non-syndromic controls with similar age, sex and body mass ...
Massimo Tanja - - 2013
PURPOSE: Allergic bronchial asthma is one of the most common chronic diseases worldwide. For many years, the climate at moderate altitude has been used as an alternative therapy for patients suffering from bronchial asthma. The aim of such therapy is to reduce the medication dose and to improve the quality ...
Lee Yang-Ja - - 2013
Hibernating squirrels slow blood flow to a crawl, but sustain no damage to brain or other tissues. This phenomenon provides an excellent model of natural tolerance to ischemia. Small ubiquitin-like modifier (SUMO) is a 100-residue peptide that modifies other proteins by being attached to the epsilon amino group of specific ...
Tang Peifu P Department of Orthopaedics, General Hospital, Beijing, - - 2013
This article reports on nine cases of proximal tibial nerve compression by the soleal tendinous arch caused by unsuitable treatment of acute compartment syndrome (ACS). Also, we report the clinical results of neurolysis and analyse the cause of this special type of neurological compression. There were nine extremities in nine ...
Sethi Roshan - - 2013
OBJECTIVES/HYPOTHESIS: To review the known histopathologic findings and clinical behavior of mammary analogue secretory carcinoma (MASC). DATA SOURCES: PubMed. REVIEW METHODS: Literature search using the terms "Mammary analogue secretory carcinoma," "Mammary analog secretory carcinoma," and "MASC" to identify all relevant publications. RESULTS: MASC is an unusual and rare malignant salivary ...
Biesbroeck Lauren K - - 2013
Telaprevir and boceprevir are novel protease inhibitors recently approved for treatment of chronic hepatitis C virus infection, and have gained widespread use. Skin rash has been reported frequently in patients treated with telaprevir, but less commonly with boceprevir. Despite a high incidence in clinical trials, the telaprevir-related eruption has not ...
Vidal A C - - 2013
INTRODUCTION: Although most invasive cervical cancer (ICC) harbor <20 human papillomavirus (HPV) genotypes, use of HPV screening to predict ICC from HPV has low specificity, resulting in multiple and costly follow-up visits and overtreatment. We examined DNA methylation at regulatory regions of imprinted genes in relation to ICC and its ...
Miyazaki Osamu - - 2013
NK012 is a micelle-forming macromolecular prodrug of 7-ethyl-10-hydroxy camptothecin (SN-38), an active metabolite of irinotecan. It is accumulated and retained in tumor tissues and gradually releases SN-38 in an enzyme-independent manner. NK012 was previously demonstrated to have stronger anti-tumor activity than irinotecan in a broad range of human solid-tumor xenograft ...
Wu Rui - - 2013
To investigate role of eye's sign in the patients with neuropsychiatric systemic lupus erythematosus (NPSLE). The scores of eye's sign in bulbar conjunctival microvascular changes were assessed in all patients according to our criteria. The disease activity was measured with SLE Disease Activity Index (SLEDAI) score. Anticardiolipin antibody (aCL) and ...
Vidotto Michele - - 2013
BACKGROUND: Sturgeons are a group of Condrostean fish with very high evolutionary, economical and conservation interest. The eggs of these living fossils represent one of the most high prized foods of animal origin. The intense fishing pressure on wild stocks to harvest caviar has caused in the last decades a ...
Berneburg M - - 2013
Plaque psoriasis is an inflammatory disease affecting approximately two percent of the population. The clinical hallmarks of psoriasis are sharply demarcated, erythematous plaques with thick scales. Photochemotherapy (PUVA) is one of the most effective therapies of psoriasis. The photosensitizer 8 methoxypsoralen (8-MOP) can be applied either orally (system PUVA) or ...
Sandoval Garrido Felipe Alfonso - - 2013
AIM: To clarify the performance situation of selected quality indicators: falls, pressure ulcers and dehydration, at health care facilities for the elderly in Japan, and what structural characteristics are related to them. METHODS: The operational population consisted of 1057 institutionalized users (approximately 10 randomly selected per facility) from a survey ...
Luo Da Sheng da - - 2013
To evaluate applicability of lives saved tool (LiST) in projecting effects of maternal health interventions on reducing maternal mortality in the rural area of Guangxi Zhuang Autonomous Region in China, and provide evidence for promoting LiST in China. By using maternal intervention coverage and other information collected through the cross-sectional ...
Koh Weon-Kyu - - 2013
Colloidal nanocrystals (NCs) of lead chalcogenides are a promising class of tunable infrared materials for applications in devices such as photodetectors and solar cells. Such devices typically employ electronic materials in which charge carrier concentrations are manipulated through "doping;" however, persistent electronic doping of these NCs remains a challenge. Here, ...
Guo Pei - - 2013
Two organoselenium compounds: xylitol selenious ester (xylitol-Se) and sucrose selenious ester (sucrose-Se) were synthesized, and their molecular structures were characterized in this study. In MTT assay, xylitol-Se and sucrose-Se showed cytostatic effects on human hepatocellular carcinoma cells SMMC-7221 in a dose-dependent manner, whereas they had no negative influences on the ...
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