Search Results
Results 701 - 750 of 2612
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Ding Caixia - - 2013
Complexes of new Schiff base ligands generated in situ from the reaction of 1-aminoglycerol, aldehydes, and metal ions are reported. [Cu4 (HL(1) )4 ] (1) and [Ni4 O(HL(1) )3 (H2 O)3 )]⋅6 H2 O⋅DMF⋅DMSO (2) have M4 O4 cubane cores, with the L/M molar ratios of 4:4 and 3:4, respectively. [Mn(III) ...
Peterson-Carmichael Stacey L - - 2013
BACKGROUND: Data supporting the clinical use of infant lung function (ILF) tests are limited making the interpretation of clinical ILF measures difficult. OBJECTIVES: To evaluate current ILF testing practices and to survey users regarding the indications, limitations and perceived clinical benefits of ILF testing. METHODS: We created a 26-item survey ...
Wang Renxue - - 2013
The bile salt export pump (BSEP), encoded by the abcb11 gene, is the major canalicular transporter of bile acids from the hepatocyte. BSEP malfunction in humans causes bile acid retention and progressive liver injury, ultimately leading to end stage liver failure. The natural, hydrophilic, bile acid ursodeoxycholic acid (UDCA) is ...
Dai Fei - - 2013
Background Desvenlafaxine succinate (DVS) is a novel SNRI. The aim of this study was to investigate the effects of DVS on visceral hypersensitivity and solid gastric emptying in a rodent model of gastric hyperalgesia. Methods Twenty eight gastric hyperalgesia rats and 20 control rats were used. Visceral sensitivity during gastric ...
Grego Alina - - 2013
Unprecedented information concerning how the relative roles of different hydrophobic effects evolve during multistep hydrophobic assembly processes is provided by using a unique type of experiment to resolve the underlying energetics of individual growth steps in the formation of a structurally well-defined micelle-like organic aggregate of n-butyrate ions within a ...
Li Jiang - - 2013
Self-assembled DNA nanostructures have emerged as a type of nano-biomaterials with precise structures, versatile functions and numerous applications. One particularly promising application of these DNA nanostructures is to develop universal nanocarriers for smart and targeted drug delivery. DNA is the genetic material in nature, and inherently biocompatible. Nevertheless, cell membranes ...
Tavakol Shima - - 2013
Bone matrix consists of two major phases at the nanoscale: organic and hydroxyapatite. Nanotechnology as a diverse and interdisciplinary area of research has the capacity to revolutionize many areas of applications such as bone tissue engineering. Nano Hydroxyapatite/Gelatin composite has higher osteoblast attachment and proliferation than micro-sized ones, and shorter ...
Ito Shigekazu - - 2013
Catenation of stable 1,3-diphopsphacyclobutane-2,4-diyl units with biphenyl-, diphenyl ether-, and diphenylmethane-based bridging groups were utilized for evaluation of the distinct through-space interaction between the electron-donating P-heterocyclic biradical chromophores. Structural properties of the oligo(biradicals), characterized by X-ray crystallography and DFT calculation, suggest a possible distance between the biradical units for the ...
Charalambous Charalambos C - - 2013
BACKGROUND: . In the past several years, several randomized controlled trials (RCTs) have been reported regarding the efficacy of treadmill-based walking-specific rehabilitation programs, either individually (TT) or combined with body weight support (BWSTT), over control group therapies poststroke. No clear consensus exists as to whether treadmill-based interventions are superior in ...
Mondal Arobendo - - 2013
Surface phonons and surface temperature may have important effects on reactions of molecules at surfaces, and at present much remains unknown about these effects. A question addressed here, which has received little attention so far, is how reaction at elevated temperature is affected by thermal lattice expansion. To answer this ...
Guerrero Javier - - 2013
BACKGROUND: Enzalutamide (formerly MDV3100 and available commercially as Xtandi®), a novel androgen receptor (AR) signaling inhibitor, blocks the growth of castration-resistant prostate cancer (CRPC) in cellular model systems and was shown in a clinical study to increase survival in patients with metastatic CRPC. Enzalutamide inhibits multiple steps of AR signaling: ...
Pelosin Elisa - - 2013
BACKGROUND: Pain is one of the most common and disabling "nonmotor" symptoms in patients with dystonia. No recent study evaluated the pharmacological or physical therapy approaches to specifically treat dystonic pain symptoms. OBJECTIVE: To evaluate the effectiveness of KinesioTaping in patients with cervical dystonia (CD) and focal hand dystonia (FHD) ...
Bondarenko A - - 2013
Background: The functions of some bone proteins, as osteopontin (OPN) and osteocalcin (OC), have been discovered by the latest studies. This fact suggests the possibility of their immunodetection to characterize peri-implant osteogenesis and implant impact on it. Methods: Cylindrical pins of Mg alloys (MgCa0.8, LAE442, ZEK100, LANd442) and titanium alloy ...
Alt Murphy Margit - - 2013
BACKGROUND: . Kinematic movement analysis is increasingly used as an outcome measure in evaluation of upper extremity function after stroke. Little is known, however, about what observed longitudinal changes in kinematics mean in the context of an individual's functioning. In this study, the responsiveness and expected change in kinematic measures ...
Zhu Ying - - 2013
This paper describes sequential operation droplet array (SODA) system, a fully-automated droplet-based microfluidic system capable of performing picoliter-scale liquid manipulation, analysis and screening. The SODA system was built using a tapered capillary-syringe pump module and a two-dimensional (2D) oil-covered droplet array installed on an x-y-z translation stage. With the system, ...
Borel Benoit - - 2013
AIM: To analyze breathing pattern and mechanical ventilatory constraints during incremental exercise in healthy and cystic fibrosis (CF) children. METHODS: Thirteen healthy children and 6 children with cystic fibrosis volunteered to perform an incremental test on a treadmill. Exercise tidal flow/volume loops were plotted every minute within a maximal flow/volume ...
Otsuka Takashi - - 2013
Selective hydrogenation of fluorinated esters with a pincer-type bifunctional catalyst, RuHCl(CO)(dpa) 1a, trans-RuH2(CO)(dpa) 1b or trans-RuCl2(CO)(dpa) 1c under mild conditions proceeds rapidly to give the corresponding fluorinated alcohols or hemiacetals in good to excellent yields. Under the optimized conditions, the hydrogenation of chiral (R)-2-fluoropropionate proceeds smoothly to give the corre-sponding ...
Kötter Sebastian - - 2013
AIMS: Titin-based myofilament stiffness is defined by the expression levels of the cardiac titin-isoforms, N2B and N2BA, and by phosphorylation of the elastic titin domains N2-B unique sequence (N2-Bus) and PEVK. Phosphorylation of the N2-Bus by cGMP-dependent protein kinase (PKG) or cAMP-dependent protein kinase (PKA) decreases titin stiffness, whereas phosphorylation ...
Saini Pradeep - - 2013
In the developed nations, temporary ileostomies are usually made in order to protect a distal anastomosis after cancer surgery. However, in India and the neighbouring countries ileal perforation is the most common indication for creating a temporary ileostomy after emergency laparotomy. It seems logical to perform a contrast study when ...
Dayan Sonia - - 2013
The WWOX gene spans the FRA16D common chromosomal fragile site and is able to suppress tumor growth. FRA16D is a frequent site of DNA instability in cancer resulting in reduced levels of WWOX expression. Altered levels of WWOX have been shown to affect metabolism. Whereas metabolic reprograming of cells from ...
Yoo Seungmin - - 2013
Down to the wire: Three-dimensional interconnected Si-based nanowires are produced through the combination of thermal decomposition of SiO and a metal-catalyzed nanowire growth process. This low-cost and scalable approach provides a promising candidate for high-capacity anodes in lithium-ion batteries.
Chen Yu - - 2013
Spiro compounds: An iodine monochloride-induced intramolecular cyclization of 1-[4'-methoxy(1,1'-biphenyl)2-yl]alkynones has been developed. An electrophilic iodocyclization selectively takes place at the ipso position (versus the ortho electrophilic aromatic substitution) to afford 4'H-spiro(cyclohexa[2,5]diene-1,1'-naphthalene)-4,4'-diones, a new group of spiroconjugated compounds.
Stuparu Mihaiela C - - 2013
A class of its own: A new class of fullerene C60 hosts-polymeric in nature-has been developed by careful design of the molecular structure of the polymer repeat unit and the mode of interaction between the repeat unit and C60 . As these hosts are synthesized by free-radical polymerization, polymer hosts ...
Arancibia Francisco - - 2013
ABSTRACT BACKGROUND In US and European literature Legionella pneumophila is reported as an important etiological agent of severe community acquired pneumonia (CAP), but in Chile this information is lacking. The aim of this study was to evaluate the incidence of severe CAP due for this agent in Santiago, Chile, and ...
Roussel Jm - - 2013
Stable isotope analysis of organic matter in sediment records has long been used to track historical changes in productivity and carbon cycling in marine and lacustrine ecosystems. While flow dynamics preclude stratigraphic measurements of riverine sediments, such retrospective analysis is important for understanding biogeochemical cycling in running waters. Unique collections ...
Baldwin Laura-Mae - - 2013
BACKGROUND: Geographic barriers and limited availability of cancer specialists may influence early prostate cancer treatment options for rural men. This study compares receipt of different early prostate cancer treatments between rural and urban patients. METHODS: Using 2004-2006 SEER Limited-Use Data, 51,982 early prostate cancer patients were identified (T1c, T2a, T2b, ...
McNamara David G - - 2013
BACKGROUND:: The upper airway humidifies and warms inspired gases before they reach the trachea, a process bypassed by the insertion of a tracheostomy, necessitating humidification of inspired gases. The optimal method of humidification is not known. METHODS:: We conducted a short term 20-hour and a long term 10-week randomised cross-over ...
Buelna-Chontal Mabel - - 2013
Chemical modification of primary amino groups of mitochondrial membrane proteins by the fluorescent probe fluorescamine induces non-specific membrane permeabilization. Titration of the lysine €-amino group promoted efflux of accumulated Ca(2+) , collapse of transmembrane potential, and mitochondrial swelling. Ca(2+) release was inhibited by cyclosporin A. Considering the latter, we assumed ...
Guerrero Jorge - - 2013
Pseudomembranous necrotizing tracheitis is a rare cause of life threatening central airway obstruction (CAO). Patients present with hoarseness, cough, dyspnea, wheezes, stridor and occasionally respiratory failure. Diagnosis requires high index of suspicion and should be confirmed with a comprehensive bronchoscopic examination and biopsy. For patients with signs and symptoms of ...
Sun Huiqing - - 2013
BACKGROUND:: Mechanical ventilation and surfactants are the standard treatment of preterm respiratory distress syndrome (RDS). The effects of the primary ventilation model on bronchopulmonary dysplasia (BPD) and long-term neurodevelopment outcomes are controversial. The purpose of this study was to compare the efficacy and safety of high-frequency oscillatory ventilation (HFOV) and ...
Walker Brian A - - 2013
IGH translocations in myeloma are a primary event and determine the prognostic outcome of a patient. These events are characterized by FISH and classical cytogenetics, but in a small proportion of samples a translocation involving the IGH locus can be detected but the partner chromosome cannot be identified. These cases ...
Someya Fujiko - - 2013
BACKGROUND:: The diffusion capacity of the lung for carbon monoxide (DLCO) is a good marker of disease severity in patients with idiopathic interstitial pneumonia, and is associated with oxygen saturation; however, little is known about this marker in systemic sclerosis patients with interstitial lung disease. We aimed to indicate the ...
Kim Dong Wook - - 2013
Aspiration of a tooth in facial trauma is a known complication. There have been few reports on the consequences of maxillofacial trauma, especially when the patient is intubated. We report on two complicated cases of multiple teeth aspiration and their removal in intubated patients. A special technique using flexible bronchoscopy ...
Jambhekar Supriya K - - 2013
BACKGROUND:: Many pediatric patients need positive airway pressure (PAP) for treatment of obstructive sleep disordered breathing (OSDB). Adherence with use of PAP equipment (defined as percent of nights with nightly use of PAP for more than 4 hours) is often poor and not sustained long- term. With any chronic disease, ...
He Qing - - 2013
Bronchoscopy technology is a desirable module for detecting lung cancers arising from central airways. Considerable early cancers and precancerous lesions are not visible on the conventional bronchoscopy - white light bronchoscopy (WLB). Autofluorescence bronchoscopy (AFB) is a newly developed technology which exploits the difference of autofluorescent intensity between normal and ...
Sutkuvienė Simona - - 2013
Multidrug efflux pump inhibitors have a great potential as pharmacological agents that increase the drug susceptibility of bacterial pathogens. Our study was focused on the synthesis and evaluation of the efficiency of resistance-nodulation-division (RND) family efflux pump inhibitors. The efficiency of these inhibitors was investigated on Salmonella enterica ser. Typhimurium ...
Lofaso Frédéric - - 2013
BACKGROUND: To maximise the likelihood of successful long term mechanical ventilation (MV) in patients with neuromuscular diseases, ventilators characteristics and settings must be chosen carefully taking into account both medical requisites and the patient's preference and comfort. The general objectives of the survey were 1) to evaluate patients comfort with, ...
Silvi Mattia - - 2013
A challenging asymmetric reaction (aza-Michael addition of imides to enones) has been optimized through an integrated approach involving the synthesis of a family of organocatalysts, multiple catalysis (usage of additives), and finally with rational exploration of the chemical space by the application of the experiment design.
Smith Barbara Kellerman - - 2013
BACKGROUND:: While inspiratory muscle weakness is common in prolonged mechanical ventilation, inspiratory muscle strength training (IMST) can facilitate strengthening and ventilator weaning. However, the inspiratory load compensation (ILC) responses to threshold loads are not well-characterized in patients. The purpose of this study was to retrospectively compare ILC responses according to ...
Oto Jun - - 2013
PURPOSE:: Because noninvasive ventilation (NIV) delivers medical gas at high flow, inadequate humidification may cause oral dryness and patient discomfort. A heated humidifier (HH) is often used to humidify inspired gas during NIV but little has been reported about its effects on hygrometric conditions inside of full face masks and ...
Lugato E - - 2013
Proposed European policy in the agricultural sector will place higher emphasis on soil organic carbon (SOC), both as an indicator of soil quality and as a means to offset CO2 emissions through soil carbon (C) sequestration. Despite detailed national SOC datasets in several European Union (EU) Member States, a consistent ...
Paiva Diana - - 2013
Graft copolymers of chitosan and maltodextrin were synthesized by reductive amination of a low molecular weight chitosan. The degree of substitution is 70% or above, as quantified by nuclear magnetic resonance spectroscopy, at molar ratios of chitosan glucosamine units and maltodextrin of 1 : 1 and 1 : 5. The high substitution degree generates ...
Sokolova Ekaterina V - - 2013
The influence of sulfated polysaccharides (λ-, κ- and κ/β-carrageenan and porphyran) - on platelet activation was studied. Carrageenans were much weaker inhibitors of a coagulation process than heparin, while porphyran had not that effect. Results of the aPTT and PT assays suppose that carrageenans affected mostly intrinsic pathway of coagulation, ...
Feng Xingmei - - 2013
Dental pulp stem cells (DPSCs) are a type of mesenchymal stem cells (MSCs) characterized by self-renewal and multi-lineage differentiation, including chondrocytes, adipocytes, neural cells and osteoblasts, which make it an attractive choice for tissue engineering purposes. Tumor necrosis factor α (TNF-α) had the positive effect on the mineralization of bone ...
Gardiner William W - - 2013
The acute toxicity of physically and chemically dispersed crude oil and the dispersant Corexit 9500 were evaluated for key Arctic species. The copepod Calanus glacialis, juvenile Arctic cod (Boreogadus saida), and larval sculpin (Myoxocephalus sp.) were tested under conditions representative of the Beaufort and Chukchi Seas during the ice-free season. ...
Sheath Karen L - - 2013
The aim of the present study was to evaluate the use of KaryoLite™ bacterial artificial chromosomes (BACs)‑on‑Beads™ (BoBs) technology for the rapid screening of products of conception (POC). Validation and prospective studies were carried out on 85 and 95 patient samples, respectively. Validation studies had previously been analyzed using routine culture ...
Noh Young-Woock - - 2013
Micelles for mucosal immunity: A mucosal vaccine system based on γ-PGA nanomicelles and viral antigens was synthesized. The intranasal administration of the vaccine system induces a high immune response both in the humoral and cellular immunity.
Chivers Douglas P - - 2013
Ocean acidification is one of the most pressing environmental concerns of our time, and not surprisingly, we have seen a recent explosion of research into the physiological impacts and ecological consequences of changes in ocean chemistry. We are gaining considerable insights from this work, but further advances require greater integration ...
Xia Youyi - - 2013
We have described a novel and facile strategy for fabricating a compact large area and high-quality Au film with a hierarchical structure (HS) by using a polyaniline slice as a reductant. The unique morphology of the as-prepared Au HS film, which is controlled by the concentration of AuCl4(-), results in ...
Klein Juliana Bagatini - - 2013
Vernonia scorpioides (Lam.) Pers., popularly known as Enxuga, Erva-de-São Simão and Piracá, has been used in folk medicine for its anti-inflammatory, wound healing and antimicrobial properties. Two polyacetylenes, 5-octa-2,4,6-triynyl-furan-2(5H)-one (1) and 8'-hydroxy 3-4 dihydrovernoniyne (2), were isolated from the dichloromethane extract fraction of V. scorpioides. In this study, polyacetylene 1 ...
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