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Boylan Jennifer Morozink JM Department of Psychology, University of Wisconsin, Madison, Madison, WI 53706, USA. - - 2013
To examine multiple aspects of anger experience and expression (frequency, outward expression, suppression, and control) as moderators of the association of social inequality, as measured by educational status, with inflammation and coagulation markers. After survey assessments via telephone and mail, Midlife in the United States respondents (N = 1054) participated ...
Gessler Arthur - - 2013
The oxygen stable isotope composition of plant organic matter (OM) (particularly of wood and cellulose in the tree ring archive) is valuable in studies of plant-climate interaction, but there is a lack of information on the transfer of the isotope signal from the leaf to heterotrophic tissues. We studied the ...
Cuspidi Cesare - - 2013
Aim. Diastolic dysfunction related to hypertensive left ventricular hypertrophy (LVH) has been shown to affect right-sided cardiac morphology and haemodynamics. As left atrial enlargement (LAE) is a marker of chronically elevated left ventricular (LV) filling pressure and diastolic dysfunction, we investigated the relationship between LAE and right ventricular hypertrophy (RVH) ...
Ladam Franck - - 2013
Hox genes encode transcription factors with important roles during embryogenesis and tissue differentiation. Genetic analyses initially demonstrated that interfering with Hox genes has profound effects on the specification of cell identity, suggesting that Hox proteins regulate very specific sets of target genes. However, subsequent biochemical analyses revealed that Hox proteins ...
Chatterjee Nivedita - - 2013
Bio-oils, which are multicomponent mixtures, were produced from two different biomass (rice straw (rice oil) and sawdust of oak tree (oak oil)) by using the slow pyrolysis process, and chemical compositional screening with GC-MS detected several hazardous compounds in both bio-oil samples. The two bio-oils vary in their chemical compositional ...
Lazzarini Zita Z Division of Public Health Law and Bioethics, University of Connecticut Health Center, 263 Farmington Ave. MC-6325, Farmington, CT 06030-6325, USA. - - 2013
More than half of US jurisdictions have laws criminalizing knowing exposure to or transmission of HIV, yet little evidence supports these laws' effectiveness in reducing HIV incidence. These laws may undermine prevention efforts outlined in the US National HIV/AIDS Strategy, in which the United States has invested substantial federal funds. ...
Hedges James H JH Brain Trauma Foundation, New York, New York 10007, - - 2013
The behavioral and neurobiological connections between play and the development of critical cognitive functions, such as attention, remain largely unknown. We do not yet know how these connections relate to the formation of specific abilities, such as spatial ability, and to learning in formal environments, such as in the classroom. ...
Liu Sali - - 2013
Alternative splicing of pre-messenger RNA (mRNA) is a fundamental mechanism by which a gene can give rise to multiple distinct mRNA transcripts, yielding protein isoforms with different, even opposing, functions. With the recognition that alternative splicing occurs in nearly all human genes, its relationship with cancer-associated pathways has emerged as ...
Vignozzi Linda - - 2013
BACKGROUND: Metabolic syndrome (MetS) and benign prostate hyperplasia (BPH)/low urinary tract symptoms (LUTS) are often comorbid. Chronic inflammation is one of the putative links between these diseases. Phosphodiesterase type 5 inhibitors (PDE5i) are recognized as an effective treatment of BPH-related LUTS. One proposed mechanism of action of PDE5 is the ...
Feng Xingmei - - 2013
Dental pulp stem cells (DPSCs) are a type of mesenchymal stem cells (MSCs) characterized by self-renewal and multi-lineage differentiation, including chondrocytes, adipocytes, neural cells and osteoblasts, which make it an attractive choice for tissue engineering purposes. Tumor necrosis factor α (TNF-α) had the positive effect on the mineralization of bone ...
Grochmal Anna - - 2013
In living cells and biomimetic systems alike, multivalent ligands in solution can induce clustering of membrane receptors. The link between the receptor clustering and the ligand binding remains however poorly defined. Using minimalist divalent ligands we develop a model that allows quantifying the modulation of receptor clustering by binding of ...
Li Lei L Shanghai Key Laboratory of Regulatory Biology, Institute of Biomedical Sciences, East China Normal University, Shanghai 200241, - - 2013
Our recent studies suggest a role for the proteasome activator REG (11S regulatory particles, 28-kDa proteasome activator)γ in the regulation of tumor protein 53 (p53). However, the molecular details and in vivo biological significance of REGγ-p53 interplay remain elusive. Here, we demonstrate that REGγ-deficient mice develop premature aging phenotypes that ...
Kushwah Sunita - - 2013
Cytokinins (CKs) and glucose (GLC) control a number of common responses in plants. We hypothesize that there may be an extensive overlap between CK and GLC signaling pathways. Microarray along with physiological analysis has been performed to find out the interdependence/overlap between CK and GLC signal transduction pathways in Arabidopsis ...
Kapur Navin K - - 2013
BACKGROUND: Ischemia-reperfusion injury worsens infarct size, a major determinant of morbidity and mortality after acute myocardial infarction (MI). We tested the hypothesis that reducing left ventricular (LV) wall stress with a percutaneous left atrial-to-femoral artery centrifugal (pLA-FA) bypass system, while delaying coronary reperfusion limits myocardial injury in a model of ...
Liberman Patrícia Helena Pecora - - 2013
BACKGROUND.: The aim of this study was to characterize the audiological profile accompanying oncological treatment in patients who had cancer in childhood and had been free of oncological treatment for at least 8 years. Our main interest lay in identifying the affected frequencies that interfered with speech intelligibility (SI) in ...
Bagnasco Annamaria - - 2013
AIM: To describe a protocol for a quantitative systematic review, to identify critique and summarize factors that influence self-management education. BACKGROUND: Self-management education enables patients to manage their condition successfully and it is associated with better self-care, good control over lifestyle and leading the best possible quality of life, notwithstanding ...
Mougari Faiza - - 2013
We report prosthetic knee arthritis in a 55-year-old diabetic man due to Granulicatella adiacens, a microorganism present in the oral flora, usually described in endocarditis but rarely in prosthesis joint infection. This patient had a dental extraction without antibiotic prophylaxis one month before, whereas an aseptic loosening of the prosthesis ...
Mikhail Fady M - - 2013
Purpose:The five segmental duplications (LCR22-D to -H) at the distal region of chromosome 22 band q11.2 in the region immediately distal to the DiGeorge/velocardiofacial syndrome deleted region have been implicated in the recurrent distal 22q11.2 microdeletions. To date, the distal 22q11.2 microdeletions have been grouped together as a single clinical ...
Lamsal Lok - - 2013
Concern is growing about the effects of urbanization on air pollution and health. Nitrogen dioxide (NO2) released primarily from combustion processes such as traffic is a short-lived atmospheric pollutant that serves as an air quality indicator, and is itself a health concern. We derive a global distribution of ground-level NO2 ...
Guirguis Emilia E Pulmonary Cardiovascular Branch, National Institutes of Health, Bethesda, Maryland 20892, USA. - - 2013
Obesity is linked to various diseases, including insulin resistance, diabetes, and cardiovascular disorders. The idea of inducing white adipose tissue (WAT) to assume characteristics of brown adipose tissue (BAT), and thus gearing it to fat burning instead of storage, is receiving serious consideration as potential treatment for obesity and related ...
Himmetoglu S - - 2013
Insulin resistance is one of the feature of obesity. Fetuin A is inhibitor of insulin receptor which belongs the family of receptor tyrosine kinase. It has been observed that fetuin-null mice are resistant to diet-induced obesity and they exhibit increased insulin sensitivity. Increased production of reactive oxygen species is suggested ...
Eng Marvin H - - 2013
Background: Transthoracic (TTE) and intracardiac echocardiography (ICE) have both been established as modalities for imaging guidance in mitral balloon valvuloplasty (MBV). Real-time 3-dimensional transesophageal echocardiography (RT3D-TEE) improves depth resolution, characterization of pathology and visualization of interventional catheters and devices. Three-dimensional imaging should enhance catheter navigation but improvements in procedural outcomes ...
Ruth Jeffrey D - - 2013
The echogenicity of the renal cortex is an important parameter to consider in dogs that are suspected to have renal dysfunction. Focal increases in echogenicity have been attributed to neoplasia, infection, calcification, fibrosis, gas, and infarction. Anisotropic backscatter has been described as a source of focally increased renal cortical echogenicity ...
Aagaard Lise - - 2013
BACKGROUND: Reporting of adverse drug reactions (ADRs) has traditionally been the sole province of healthcare professionals. In the European Union, more countries have allowed consumers to report ADRs directly to the regulatory agencies. The aim of this study was to characterize ADRs reported by European consumer for nervous system medications. ...
Tannenbaum David - - 2013
Companies often provide incentives for employees to maintain healthy lifestyles. These incentives can take the form of either discounted premiums for healthy-weight employees ("carrot" policies) or increased premiums for overweight employees ("stick" policies). In the three studies reported here, we demonstrated that even when stick and carrot policies are formally ...
Shi Tujin T Biological Sciences Division, Pacific Northwest National Laboratory, Richland, Washington, - - 2013
We recently reported an antibody-free targeted protein quantification strategy, termed high-pressure, high-resolution separations with intelligent selection and multiplexing (PRISM), for achieving significantly enhanced sensitivity using selected reaction monitoring (SRM) mass spectrometry. Integrating PRISM with front-end IgY14 immunoaffinity depletion, sensitive detection of targeted proteins at 50-100 pg/mL levels in human blood ...
Chirife Raul - - 2013
BACKGROUND: Our objective was to evaluate the systolic index (SI), the ratio between rate-corrected left ventricular ejection time (LVETc), and a preejection period surrogate (PEPsu), to assess cardiac function in patients with DDD and cardiac resynchronization therapy (CRT) pacemakers. METHODS: LVETc and PEPsu were automatically measured from electrocardiogram and finger ...
Isaacs Aaron - - 2013
OBJECTIVE: Circulating levels of total cholesterol, low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol, and triglycerides are recognized risk factors for cardiovascular disease. We tested the hypothesis that the cumulative effects of common genetic variants for lipids are collectively associated with subclinical atherosclerosis and incident coronary heart disease. APPROACH AND RESULTS: ...
Ozawa Fumisato - - 2013
In this study, we developed a novel method for fabricating microwell arrays constructed from alginate gels, and the alginate gel microwells were used for three-dimensional (3D) cell culture. The alginate gel microwells were fabricated on a patterned ITO electrode using alginate gel electrodeposition. Embryonic stem (ES) cells or hepatocellular carcinoma ...
Donaldson L A - - 2013
Wood cell walls fluoresce as a result of UV and visible light excitation due to the presence of lignin. Fluorescence spectroscopy has revealed characteristic spectral differences in various wood types, notably normal and compression wood. In order to extend this method of characterising cell walls we examined the fluorescence lifetime ...
Brown Steffen A - - 2013
Objective The objective of this investigation was to determine maternal ground transport times from community hospitals to the nearest hospital offering comprehensive (level III) neonatal care within the contiguous United States.Study Design This observational study combined data from the 2010 U.S. Census tract and 2010 American Hospital Association Annual Survey. ...
Gee Bryan M - - 2013
Sound-based interventions (SBIs) involve listening to psychoacoustically modified music as a means for promoting new neural pathways in individuals with neurological dysfunction. Multiple forms of SBIs exist and are being used by healthcare professionals despite the lack of evidence to support their efficacy. The purpose of this study was to ...
Bondarenko A - - 2013
Background: The functions of some bone proteins, as osteopontin (OPN) and osteocalcin (OC), have been discovered by the latest studies. This fact suggests the possibility of their immunodetection to characterize peri-implant osteogenesis and implant impact on it. Methods: Cylindrical pins of Mg alloys (MgCa0.8, LAE442, ZEK100, LANd442) and titanium alloy ...
Smith Barbara Kellerman - - 2013
BACKGROUND:: While inspiratory muscle weakness is common in prolonged mechanical ventilation, inspiratory muscle strength training (IMST) can facilitate strengthening and ventilator weaning. However, the inspiratory load compensation (ILC) responses to threshold loads are not well-characterized in patients. The purpose of this study was to retrospectively compare ILC responses according to ...
Mushkbar M - - 2013
BACKGROUND AND OBJECTIVES: Red cell antibodies may complicate blood provision and liver transplantation outcome. The aim of this survey was to document red cell antibodies in adults undergoing liver transplantation and make recommendations for clinical practice. MATERIALS AND METHODS: We completed a 10-year retrospective review of adults undergoing liver transplant, ...
Ma Jingyuan - - 2013
An in situ X-ray absorption fine structure (XAFS) experiment has been performed to observe the evolution of gold nanoparticles in the ionic liquid [BMIM][AuCl4], by hard X-ray irradiation. The ionic liquid acts as both a reducing agent and a protective ligand. A synchrotron-based X-ray plays the role of the irradiation ...
Cambon A - - 2013
Amphiphilic polymeric micelles greatly improve the solubilization and sustained release of hydrophobic drugs and provide a protective environment for the cargo molecules in aqueous media, which favors lower drug administration doses, reduces adverse side effects, increases in blood circulation times and passive targeting to specific cells. These capabilities depend, amongst ...
Kirschner Benny - - 2013
OBJECTIVE: Human papillomavirus (HPV) genotype distributions in invasive cervical cancers may differ by geographic region. The primary objective of this study was to estimate HPV-genotype distribution in Danish women with diagnosis of invasive cervical cancer. DESIGN: Observational, cross-sectional. POPULATION: Danish data from a multi-center study undertaken in 12 European countries. ...
Murata A A Department of Gastroenterological Surgery, Graduate School of Medical Science, Kumamoto University, 1-1-1 Honjo, Kumamoto City, Kumamoto, - - 2013
LINE-1 methylation level is a surrogate marker of global DNA methylation. LINE-1 methylation in primary colorectal cancers (CRCs) is highly variable and strongly associated with a poor prognosis. However, no study has examined LINE-1 methylation levels of metastatic CRCs in relation to prognosis or assessed the heterogeneity of LINE-1 methylation ...
Kang Soo-Jin - - 2013
Background In left main coronary artery (LMCA) bifurcation lesions, hemodynamic and geometrical change in left circumflex artery (LCX) ostium after main branch (MB) stenting has not been known. This study evaluated how accurately intravascular ultrasound (IVUS) predicts the functional compromise of the sidebranch. Methods A single-stent cross-over technique was used ...
König Stefan Alexander - - 2013
Purpose Illustrative cases are presented to demonstrate the surgical management of complex instability of the cervical spine.Methods Six patients with different underlying pathologies are presented along with their clinical and radiologic findings, surgical procedures, complications, and outcomes.Results Five patients underwent anteroposterior (AP) decompression and stabilization, of which two required secondary ...
Kamitani Takeshi - - 2013
BACKGROUND:Few studies have documented catastrophic head and neck injuries in judo, but these injuries deserve greater attention. PURPOSE:To determine the features of catastrophic head and neck injuries in judo. STUDY DESIGN:Descriptive epidemiological study. METHODS:This study was based on the accident reports submitted to the All Japan Judo Federation's System for ...
Brandenburg Jan Gerit - - 2013
A combined X-ray diffraction and theoretical study of the solid-state molecular and crystal structures of tribenzotriquinacene (TBTQ, 2) and its centro-methyl derivative (3) is presented. The molecular structure of the parent hydrocarbon displays C3v symmetry and the three indane wings adopt mutually orthogonal orientations, similar to the case in its ...
Yingjun Guo - - 2013
Hypoxia represents the lack of oxygen below the basic level, and the range of known channels related to hypoxia is continually increasing. Since abnormal hypoxia initiates pathological processes in numerous diseases via, to a great degree, producing acidic microenvironment, the significance of these channels in this environment has, until now, ...
Saini Pradeep - - 2013
In the developed nations, temporary ileostomies are usually made in order to protect a distal anastomosis after cancer surgery. However, in India and the neighbouring countries ileal perforation is the most common indication for creating a temporary ileostomy after emergency laparotomy. It seems logical to perform a contrast study when ...
Sokolova Ekaterina V - - 2013
The influence of sulfated polysaccharides (λ-, κ- and κ/β-carrageenan and porphyran) - on platelet activation was studied. Carrageenans were much weaker inhibitors of a coagulation process than heparin, while porphyran had not that effect. Results of the aPTT and PT assays suppose that carrageenans affected mostly intrinsic pathway of coagulation, ...
Bonaparte James P - - 2013
BACKGROUND: Botulinum toxin A is a commonly used biological medication in the field of facial plastic surgery. Currently, there are three distinct formulations of botulinum toxin A, each with their purported benefits and advantages. However, there is considerable confusion as to the relative efficacy and side-effects associated with each formulation. ...
Hariharan Kandasamy K Cancer Therapeutics, Biogen Idec, San Diego, CA 92122, - - 2013
Galiximab is a primatized monoclonal antibody that targets CD80 expressed on malignant B cells and is being studied in the clinic as a potential treatment for follicular NHL. We have recently reported that galiximab signals B-NHL cells in vitro and inhibits cell growth and sensitizes resistant tumor cells to apoptosis ...
Van Hus Janeline W P - - 2013
BACKGROUND: Very low birth weight (VLBW) infants are at increased risk for motor deficits, which may be reduced by early intervention programs. For detection of motor deficits, and to monitor intervention, different assessment tools are available. It is important to choose tools that are sensitive to evaluate the efficacy of ...
Stead Lucy F - - 2013
Current methods for resolving genetically distinct subclones in tumour samples require somatic mutations to be clustered by allelic frequencies, which are determined by applying a variant calling program to next-generation sequencing data. Such programs were developed to accurately distinguish true polymorphisms and somatic mutations from the artifactual non-reference alleles introduced ...
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