Search Results
Results 601 - 650 of 2623
< 8 9 10 11 12 13 14 15 16 17 18 >
Kong Linghua L Diabetes Research Program, Division of Endocrinology, Department of Medicine, NYU School of Medicine, New York, NY 10016, - - 2013
Subjects with diabetes mellitus are at high risk for developing atherosclerosis through a variety of mechanisms. Because the metabolism of glucose results in production of activators of protein kinase C (PKC)β, it was logical to investigate the role of PKCβ in modulation of atherosclerosis in diabetes mellitus. ApoE(-/-) and PKCβ(-/-)/ApoE(-/-) ...
Sledge Daniel - - 2013
Until the 1930s, malaria was endemic throughout large swaths of the American South. We used a Poisson mixture model to analyze the decline of malaria at the county level in Alabama (an archetypical Deep South cotton state) during the 1930s. Employing a novel data set, we argue that, contrary to ...
Choi Ui Yoon - - 2013
Japanese encephalitis virus is a common cause of encephalitis in Asian children; therefore, maintenance of immunity against Japanese encephalitis virus is essential. Although many countries recommend booster vaccination, some trials have concluded that administration of one or two vaccinations is sufficient. The current study was conducted to evaluate immunogenicity and ...
Vegge Andreas A Dept. of Human Nutrition, Faculty of Life Sciences, Univ. of Copenhagen, 30 Rolighedsvej, DK-1870 Frederiksberg C, Denmark. - - 2013
Short bowel syndrome (SBS) is a frequent complication after intestinal resection in infants suffering from intestinal disease. We tested whether treatment with the intestinotrophic hormone glucagon-like peptide-2 (GLP-2) increases intestinal volume and function in the period immediately following intestinal resection in preterm pigs. Preterm pigs were fed enterally for 48 ...
Chivers Douglas P - - 2013
Ocean acidification is one of the most pressing environmental concerns of our time, and not surprisingly, we have seen a recent explosion of research into the physiological impacts and ecological consequences of changes in ocean chemistry. We are gaining considerable insights from this work, but further advances require greater integration ...
Wen Yalu - - 2013
Abstract The genomic wave has been identified as a major artifact in genome data and is highly correlated with the sequence GC content. Although statistical methods have been developed to filter this artifact, the mechanism underlying the genomic wave has not been studied yet. Understanding of the artifact, specifically the ...
Kudo Mayumi - - 2013
Controlling the spatial organization of proteinogenic side chains is critical to develop protein mimics with selective recognition properties toward target protein surfaces. We present a novel methodology to produce a linear array of proteinogenic residues based on the incorporation of α-amino acids into sequences of rigid, helically folded, oli-goamides of ...
Lautner Silke - - 2013
Leaf photosynthesis of the sensitive plant Mimosa pudica displays a transient knockout in response to electrical signals induced by heat stimulation. This study aims at clarifying the underlying mechanisms, in particular, the involvement of respiration. To this end, leaf gas exchange and light reactions of photosynthesis were assessed under atmospheric ...
Kotur Zorica - - 2013
Nitrite-specific plasma membrane transporters have been described in bacteria, algae and fungi, but there is no evidence of a nitrite-specific plasma membrane transporter in higher plants. We have used 13NO2 - to characterize nitrite influx into roots of Arabidopsis thaliana. Hydroponically grown Arabidopsis mutants, defective in high-affinity nitrate transport, were used ...
Lin Zaifu - - 2013
A series of thermoresponsive and biocompatible ABA triblock copolymers in which the outer A blocks comprise poly(N-isopropylacrylamide) and the central B block consists of O-phosphoethanolamine (PEA) grafted polyacrylic acid (PAA(PEA)) are achieved by atom transfer radical polymerization (ATRP) and subsequent modification. At a relatively low concentration (2 w/v% in PBS), ...
Brouard Cécile - - 2013
BACKGROUND: Little is known about the knowledge, perceptions and prevention practices of the French general population with respect to Hepatitis B virus (HBV) infection. This article describes this population's knowledge of HBV, their perceptions of the disease, and associated screening and vaccination practices. It compares these indicators with those observed ...
Pica Monica - - 2013
Gels of α-type zirconium(IV) phosphate alkylphosphonates, ZP(Cn)x, were prepared by reacting, at room temperature, propanol intercalated nanosized α-zirconium phosphate (α-ZrP) with propanol solutions of alkylphosphonic acids (H2Cn, n = number of carbon atoms in the alkyl chain = 4, 5, 6), with (H2Cn/Zr) molar ratios in the range 0.4-4.0. (31)P ...
Iversen Jenny - - 2013
Objectives. We examined trends in HCV incident infection among injection drug users (IDUs) attending needle and syringe programs (NSPs) in Australia in 1995 to 2010. Methods. We created a passive retrospective cohort of 724 IDUs who tested negative for HCV antibodies by a simple deterministic method linking partial identifiers to ...
Hur Jung-Woo - - 2013
Study Design Technical case report.Objective The authors report surgical experience of treating contained or noncontained lumbar disc herniation (LDH) at the L3-L4 and L4-L5 or L4-L5 and L5-S1 levels by transforaminal percutaneous endoscopic lumbar discectomy and annuloplasty (PELDA) through the single entry point.Summary of Background Data When there are concurrent ...
Katare Rajesh R Experimental Cardiovascular Medicine, Bristol Heart Institute, School of Clinical Sciences, University of Bristol, Bristol, United - - 2013
To test the therapeutic activity of perivascular transplantation of encapsulated human mesenchymal stem cells (MSCs) in an immunocompetent mouse model of limb ischemia. CD1 mice underwent unilateral limb ischemia, followed by randomized treatment with vehicle, alginate microbeads (MBs), MB-encapsulated MSCs (MB-MSCs), or MB-MSCs engineered with glucagon-like peptide-1. Treatments were applied ...
Beaudry Jacqueline L - - 2013
Corticosterone (CORT) and other glucocorticoids cause peripheral insulin resistance and compensatory increases in β-cell mass. A prolonged high-fat diet (HFD) induces insulin resistance and impairs β-cell insulin secretion. This study examined islet adaptive capacity in rats treated with CORT and a HFD. Male Sprague-Dawley rats (age6 weeks) were given exogenous ...
Lynne-Landsman Sarah D SD Department of Health Outcomes and Policy and the Institute for Child Health Policy, University of Florida College of Medicine, Gainesville, FL, USA. - - 2013
Medical marijuana laws (MMLs) have been suggested as a possible cause of increases in marijuana use among adolescents in the United States. We evaluated the effects of MMLs on adolescent marijuana use from 2003 through 2011. We used data from the Youth Risk Behavior Survey and a difference-in-differences design to ...
Guerrero Javier - - 2013
BACKGROUND: Enzalutamide (formerly MDV3100 and available commercially as Xtandi®), a novel androgen receptor (AR) signaling inhibitor, blocks the growth of castration-resistant prostate cancer (CRPC) in cellular model systems and was shown in a clinical study to increase survival in patients with metastatic CRPC. Enzalutamide inhibits multiple steps of AR signaling: ...
Suemori Akio - - 2013
In order to elucidate the molecular mechanism of the catalytic reaction and enzyme conformation, we substituted 53 conserved residues identified by aligning 92 p-hydroxybenzoate hydroxylase sequences and 19 non-conserved residues selected from crystallographic studies of Pseudomonas fluorescens NBRC14160 p-hydroxybenzoate hydroxylase with 19 other naturally occurring amino acids, yielding a database ...
Kloner Robert A - - 2013
Oxygen Supply/Demand Approach to Reducing Infarct Size Great strides have been made in the treatment of acute myocardial infarction (MI). Improved outcomes and reduced mortality are largely the result of opening the occluded infarct artery as soon as possible and by keeping it open. Early reperfusion consistently reduces myocardial infarct ...
Mazairac Albert H A - - 2013
BACKGROUND: Despite the growing interest in haemodiafiltration (HDF), there is no information on the costs and cost-utility of this dialysis modality yet. It was therefore our objective to study the cost-utility of HDF versus haemodialysis (HD). METHODS: A cost-utility analysis was performed using a Markov model. It included data from ...
Berti Francesco - - 2013
The reductive cleavage of nitrosobenzene-derived cycloadducts with appropriately protected 1,2-dihydropyridines allows a novel and simple obtainment of substituted N-[1-(1-phenyl-1H-pyrrol-2-yl)alkylamides. This synthesis can also be carried out in a very simple, mild and practical one-pot procedure without isolation of the corresponding nitrosobenzene cycloadduct.
Truninger R - - 2013
To investigate the effect of prolonged acute mental stress by means of a driving training on glucose control in patients with type 1 and type 2 diabetes mellitus.39 patients with insulin-treated diabetes (18 type 1, 21 type 2 diabetes) were exposed to mental stress by means of a 2 h-driving ...
Ahmadi Azal - - 2013
Hymenoplasty, practiced in societies wherein a woman's virginity signifies honour, is a controversial surgery raising a multitude of ethical issues. There is a dearth of research uncovering the views of physicians who perform hymenoplasty, especially in sexually conservative cultures, such as Iran. Interviews were conducted with five Iranian physicians who ...
Escobar Miguel - - 2013
Hemophilia A (HA) and hemophilia B (HB) are X-linked, recessive disorders. Although their clinical manifestations are essentially indistinguishable, it has been suggested that bleeding episodes in patients with HA are generally more severe and occur at higher frequency than in patients with HB. Nevertheless, considerable debate remains regarding the relative ...
Roussel Jm - - 2013
Stable isotope analysis of organic matter in sediment records has long been used to track historical changes in productivity and carbon cycling in marine and lacustrine ecosystems. While flow dynamics preclude stratigraphic measurements of riverine sediments, such retrospective analysis is important for understanding biogeochemical cycling in running waters. Unique collections ...
Pawar Samir Kundlik - - 2013
A world of possibilities: Gold-catalyzed reactions of 2-ethynylbenzyl ethers with organic oxides and α-diazoesters gave 1,3-dihydroisobenzofuran and naphthalene derivatives, respectively (see scheme; EWG=electron-withdrawing group). Mechanisms for the formation of the formal cycloadducts were elucidated by isotope labeling.
Zhao Xu - - 2013
The effects of S atom surface adsorption and substitution on the helical surface states of Sb2Te3 are studied by the density-functional theory with spin-orbit coupling being taken into account self-consistently. It is found that S atoms play the role of surface passivation when adsorbed on both surfaces of a 6QL ...
Makhalanyane Thulani P TP 1] Department of Genetics, Centre for Microbial Ecology and Genomics, University of Pretoria, Pretoria, South Africa [2] Institute for Microbial Biotechnology and Metagenomics, University of the Western Cape, Cape Town, South - - 2013
Hypoliths (cryptic microbial assemblages that develop on the undersides of translucent rocks) are significant contributors to regional C and N budgets in both hot and cold deserts. Previous studies in the Dry Valleys of Eastern Antarctica have reported three morphologically distinct hypolithic community types: cyanobacteria dominated (type I), fungus dominated ...
Zhang B B International Cooperation Laboratory on Signal Transduction, Eastern Hepatobiliary Surgery Institute, Second Military Medical University, 225 Changhai Road, Shanghai 200438, People's Republic of - - 2013
Asparagine synthetase (ASNS) is associated with drug resistance in leukaemia, and the function of this enzyme in the context of hepatocellular carcinoma (HCC) is not clear. In this study, the relationship between ASNS expression and clinical outcomes after surgical resection was investigated, and the therapeutic value of ASNS was also ...
Losiniecki Andrew J - - 2013
Background One structure, the ligamentum flavum, nearly always encountered in lumbar spinal operations, has not been examined as an important anatomical landmark. In this context, we describe its relevance in corridors of small surgical exposures created by minimally invasive spinal approaches.Material and Methods In cadaveric and intraoperative dissections, we introduce ...
Knippenberg S - - 2013
OBJECTIVE: Insufficient sun exposure and vitamin D deficiency have both been associated with increased risk of multiple sclerosis (MS). Depressi on, anxiety, fatigue and cognitive impairment are prevalent and disabling symptoms in MS. Our objective was to examine the associations between personal sun exposure and serum 25-hydroxyvitamin D (25(OH)D), and ...
Kasumov Takhar T Department of Gastroenterology and Hepatology, Case Western Reserve University School of Medicine, Cleveland Clinic, Cleveland, OH 44195, - - 2013
High-density lipoprotein (HDL) promotes reverse cholesterol transport from peripheral tissues to the liver for clearance. Reduced HDL-cholesterol (HDLc) is associated with atherosclerosis; however, as a predictor of cardiovascular disease, HDLc has limitations because it is not a direct marker of HDL functionality. Our objective was to develop a mass spectrometry-based ...
Stevanovic Svetlana - - 2013
Generally, the magnitude of pollutant emissions from diesel engines running on biodiesel fuel is ultimately coupled to the structure of respective molecules that constitutes the fuel. Previous studies demonstrated the relationship between organic fraction of PM and its oxidative potential. Herein, emissions from a diesel engine running on different biofuels ...
Struik Fransien M - - 2013
BACKGROUND: Non-invasive positive pressure ventilation (NIPPV) is effective in treating acute exacerbations of chronic obstructive pulmonary disease (COPD). Nocturnal non-invasive positive pressure ventilation (nocturnal-NIPPV) has been proposed as an intervention for stable hypercapnic patients with COPD. OBJECTIVES: To assess the effects of nocturnal-NIPPV at home via nasal mask or face ...
Mimiaga Matthew J MJ Harvard Medical School/Massachusetts General Hospital, 1 Bowdoin Square, 7th floor, Boston, MA 02114, USA. - - 2013
The purpose of this study was to better understand substance use behaviors and deleterious health consequences among individuals with HIV. We examined a multicenter cohort of HIV-infected patients (n = 3,413) receiving care in 4 US cities (Seattle, Birmingham, San Diego, Boston) between December 2005 and April 2010 in the Centers for ...
Oto Jun - - 2013
PURPOSE:: Because noninvasive ventilation (NIV) delivers medical gas at high flow, inadequate humidification may cause oral dryness and patient discomfort. A heated humidifier (HH) is often used to humidify inspired gas during NIV but little has been reported about its effects on hygrometric conditions inside of full face masks and ...
Emami-Nemini Alexander - - 2013
G protein-coupled receptors (GPCRs) and their ligands are traditionally characterized by radioligand-binding experiments. These experiments yield excellent quantitative data, but have low temporal and spatial resolution. In addition, the use of radioligands presents safety concerns. Here we provide a general procedure for an alternative approach with high temporal and spatial ...
Walker Robert W M - - 2013
BACKGROUND: Pulmonary aspiration of gastric contents is a potentially devastating complication of anesthesia. AIMS: This prospective multicenter survey of specialist pediatric centers in the UK set out to elucidate the incidence, risk factors, and the outcome of such events. The survey took place over a twelve-month period via a web-based ...
Mittal Sukant - - 2013
The microfluidic isolation of target cells using adhesion-based surface capture has been widely explored for biology and medicine. However, high-throughput processing can be challenging due to interfacial limitations such as transport, reaction, and non-specific fouling. Here, it is shown that antibody-functionalized capture surfaces with discontinuous permeability enable efficient target cell ...
Reid Marion E - - 2013
BACKGROUND: Anti-Lan has been implicated in hemolytic transfusion reactions and hemolytic disease of the fetus and newborn. The LAN blood group system is encoded by ABCB6, whose gene product, ABCB6, belongs to the ATP-binding cassette (ABC) efflux transporter superfamily. The purpose of this study was to characterize additional alleles by ...
Veenboer Paul W - - 2013
Abstract Purpose: To identify physical, emotional and psychosocial issues in the older person with spina bifida (SB). Method: Members of the Dutch patients' association aged >25 years (n = 184) were asked to complete a questionnaire. This survey contained questions on physical and psychosocial complaints, as well as problems regarding social participation. ...
Yang Joanna C - - 2013
BACKGROUND: We examined patterns of failure in pediatric patients with thoracic sarcoma and pulmonary metastases treated with intensity-modulated radiation therapy with dose-painting (DP-IMRT). PROCEDURE: Eleven pediatric patients, five with Ewing sarcoma family tumors (ESFT) and six with rhabdomyosarcoma (RMS), with primary thoracic tumors and pulmonary metastases underwent DP-IMRT with chemotherapy ...
Kim Stanley E - - 2013
The purpose of this retrospective study was to compare the accuracy of computed tomographic angiography (CTA) and abdominal ultrasonography in detecting and characterizing portosystemic shunts (PSS) in dogs. Medical records of 76 dogs that underwent CTA and/or abdominal ultrasonography suspected to have PSS were reviewed. Presence or absence, and characterization ...
Kobayakawa Yu - - 2013
Making scab(ronine)s: The total synthesis of (-)-scabronine G features a highly stereoselective oxidative dearomatization/intramolecular inverse-electron-demand Diels-Alder reaction cascade, and the first total synthesis of (-)-scabronine A comprises a highly stereoselective oxa-Michael/protonation/acetalization cascade. The first total synthesis of (-)-episcabronine A includes another highly stereoselective cascade.
Ding Caixia - - 2013
Complexes of new Schiff base ligands generated in situ from the reaction of 1-aminoglycerol, aldehydes, and metal ions are reported. [Cu4 (HL(1) )4 ] (1) and [Ni4 O(HL(1) )3 (H2 O)3 )]⋅6 H2 O⋅DMF⋅DMSO (2) have M4 O4 cubane cores, with the L/M molar ratios of 4:4 and 3:4, respectively. [Mn(III) ...
Zhou Lin - - 2013
OBJECTIVE: Expression of microRNA-22 (miR-22) and ezrin protein (a membrane-cytoskeleton linking protein) in hepatocellular carcinoma (HCC) was investigated. METHODS: Specimens of HCC and paracancerous tissue (control; ∼5 cm away from tumour tissue) were collected from 192 patients. miR-22 expression was detected by real-time polymerase chain reaction; ezrin protein expression in tumour ...
Chou Li-Wei - - 2013
Multimodal plasmonic resonances: Silicon nanowires that contain multiple, dimensionally controlled, axially registered doped regions were synthesized and investigated by angle-dependent mid-infrared spectroscopy (see picture; P=partial pressure). The wires support mid-infrared multimodal localized surface plasmon resonances (LSPRs).
Saleem Muhammad M 1] Department of Environmental Microbiology, Helmholtz Centre for Environmental Research-UFZ, Leipzig, Germany [2] Department of Biological Sciences, University of Pittsburgh, Pittsburgh, PA, - - 2013
Predation influences prey diversity and productivity while it effectuates the flux and reallocation of organic nutrients into biomass at higher trophic levels. However, it is unknown how bacterivorous protists are influenced by the diversity of their bacterial prey. Using 456 microcosms, in which different bacterial mixtures with equal initial cell ...
Rapues Jenna - - 2013
Objectives. We evaluated the use of respondent-driven sampling (RDS) among a high-risk population of transfemales. We also obtained up-to-date epidemiological data on HIV infection and related correlates among this population. Methods. We evaluated the utility of RDS in recruiting a sample of 314 transfemales in San Francisco, California, from August ...
< 8 9 10 11 12 13 14 15 16 17 18 >