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Błaszczak-Swiatkiewicz Katarzyna - - 2013
A series of new benzimidazole derivatives with potential anticancer activity were tested as a new topoisomerase I inhibitors. The fluorometric method was used to determine in vitro the quantitative level of plasmid DNA relaxation by these compounds. Optimization of the fluorometric system and validation of the established analytical method were ...
Zhao Lian-Ming - - 2013
To primarily study the influence of recombination abnormality in human spermatocyte meiosis on the pathology of the patients with non-obstructive azoospermia (NOA). We obtained testis tissues from 6 NOA patients by testicular biopsy and divided the tissue of each patient into 2 portions, one for pathological examination and the other ...
Sabzwari Saniya Raghib - - 2013
Polypharmacy has now increasingly come into focus as the recipient of healthcare in old age worldwide. In elderly it is associated with frequent adverse drug reactions (ADRs) and drug-drug interactions resulting in significant morbidity. Geriatrics is still an emerging specialty in South Asia, especially in Pakistan, where multiple reasons for ...
Pielmeier Ricarda - - 2013
In a nearly two-year-old ram, descending from a breeding trial to investigate the effects of shortness of the lower jaw (brachygnathia inferior), a congenital cardiac anomaly was observed. At the age often months the affected animal, a cross breed of Cameroon Sheep and East Friesian Milk Sheep, showed exercise-induced respiratory ...
Shibasaki Atsushi - - 2013
Background and objective: MostGraph is an apparatus for measuring respiratory resistance and respiratory reactance, using the forced oscillation technique. Because these parameters are measured during tidal breathing of subjects, measuring technique is easy with little burden on subjects. In the present study, we conducted spirometry and MostGraph at the same ...
Klonoff David C DC Mills-Peninsula Health Services, 100 S. San Mateo Dr., San Mateo, CA 94401, USA. - - 2013
mHealth is an emerging concept in health care and uses mobile communications devices for health services and information. Mobile phones, patient monitoring devices, tablets, personal digital assistants, and other wireless devices can be part of mHealth systems. With mHealth systems, glucose data can now be automatically collected, transmitted, aggregated with ...
Agarwal Sumit - - 2013
Ovarian cancer is one of the neoplasms affecting the reproductive tract associated with high mortality rate because of limited therapeutic options and an elevated incidence of chemoresistance and recurrence. In this context, immunotherapy may constitute a promising approach to improve survival rates and clinical outcome, raising the need for specific ...
Eiró Noemi - - 2013
Breast tumors infiltrated by matrix metalloprotease 11 (MMP-11)(+) mononuclear inflammatory cells are prone to form metastases; express high levels of interleukin (IL)-1, IL-5, IL-6, IL-17, interferon β (IFNβ) and NFκB; and exhibit an increased CD68(+)/(CD3(+)CD20(+)) cell ratio at their invasive front. These factors, which are implicated in the crosstalk between ...
Sobotka Paul A PA Cibiem Inc., New York, NY 10001 , USA. - - 2013
Our aim was to highlight the very recent and rapid expansion of a number of contemporary, pioneering and projected interventional approaches for resistant hypertension. Our discussions of each approach centre on a new model of the cardiovascular system that emphasises the importance of the sympathetic nervous system, its differential control ...
Wang Tong-Sheng - - 2013
To study the effects of Wuzi Yanzong Pills (WYP) on sperm mitochondrial membrane potential (MMP) and its ultrastructure in oligoasthenotspermia model rats. Oligoasthenotspermia models were made in 50 male rats weighing 200 - 220 g by intragastric administration of Tripterygium Glucosides at 30 mg per kg per d for 8 ...
Midura-Nowaczek Krystyna - - 2013
Effects of eight short peptides containing lysine and epsilon-aminocaproic acid (EACA) on prolongation of the clot lysis time, as well as hemolytic and antibacterial activities were investigated. Interaction with plasmids pBR322 and pUC19 with the use of ethidium bromide assay and determination of influence on the activity of topoisomerase I ...
Rehman Rehana - - 2013
To compare estradiol-to-progesterone ratio with pregnancy outcome in patients of intracytoplasmic sperm injection. The quasi-experimental study was conducted on 106 couples at an assisted reproductive clinic in Islamabad from June 2010 to August 2011. Down-regulation of females aged 18-41 with Gonadotrophin releasing hormone agonist was followed by calculated stimulation with ...
Hilla Dorothea - - 2013
In this study, the prevalences of osteochondral fragments in the distal (DUI) and proximal interphalangeal joints (PIJ) as well as in the fetlock, hock and stifle joints, of palmar/plantar osteochondral fragments in the fetlock joints (POFs) and of osteochondrosis dissecans (OCD) in fetlock, hock and stifle joints were estimated in ...
Rubio Jose M - - 2013
Although psychiatric disorders are associated with decreased health-related quality of life, it is unknown whether symptom remission is associated with its improvement or normalization. Data were derived from the National Epidemiologic Survey on Alcohol and Related Conditions, a large national sample of the United States population. A total of 34,653 ...
Freeman Kurt A KA Oregon Health & Science University, 707 SW Gaines, Portland, OR 97239, USA. - - 2013
Increasingly various technologies are being tested to deliver behavioral health care. Delivering services via videoconferencing shows promise. Given that the patient-provider relationship is a strong predictor of patient adherence to medical regimens, addressing relationship quality when services are not delivered face-to-face is critical. To that end, we compared the therapeutic ...
Zielinski Ruth E - - 2013
Sexual health problems are common in women and have the potential to affect all aspects of their lives. These issues can include diminished or lack of desire for sex, difficulty with arousal and sexual pleasure, inability to orgasm, and pain with sex. Causes of sexual health issues can be complex ...
Randall Jonathan K - - 2013
The field of coloproctology covers the treatment of both benign and cancerous disease of the colon, rectum and anus. Significant recent developments in the surgical treatment of colorectal cancer include the development of minimally invasive techniques for colorectal resections and the use of stenting for obstructed patients. The introduction of ...
Al-Achkar Walid - - 2013
The so-called Philadelphia (Ph) chromosome is present in more than 90% of chronic myeloid leukemia (CML) cases. Amplification or duplication of the BCR-ABL gene has been found to be one of the key factors leading to drug resistance to imatinib mesylate (IM). In the present study, we identified the presence ...
Karabay Oguz - - 2013
To investigate the frequency of nasal Helicobacter pylori carriage among cooks living in Bolu, Ardahan and Sakarya province of Turkey. A total of 54 cooks (10 from Bolu, 29 from Ardahan and 15 from Sakarya) were enrolled. Nasal Helicobacter was tested using polymerase chain reaction. Helicobacter pylori was detected in ...
Gunathilake Waruna W Ministry of Health Sri Lanka, Colombo, Sri - - 2013
We retrospectively compared glycemic control and glycemic burden in type 2 diabetes patients treated by general physicians with access to decision support with those treated by general physicians without access to decision support. A total of 875 patients [471 (53.8%) males] aged 54.3 [standard deviation (SD) 13.1] years followed up ...
Macfarlan Shane J SJ Department of Anthropology, University of Missouri, 107 Swallow Hall, Columbia, MO 65211, USA. - - 2013
Prosocial reputations play an important role, from the evolution of language to Internet transactions; however, questions remain about their behavioural correlates and dynamics. Formal models assume prosocial reputations correlate with the number of cooperative acts one performs; however, if reputations flow through information networks, then the number of individuals one ...
Chen Yuanyuan - - 2013
Chronic neutrophilic leukemia (CNL) is an infrequently encountered myeloproliferative disorder characterized by sustained neutrophilic leukocytosis, hepatosplenomegaly and the absence of the Philadelphia chromosome. This study presents a 60-year-old male patient with a diagnosis corresponding to the WHO classification criteria for CNL who was treated at the First Affiliated Hospital of ...
Dogan Nurettin Ozgür - - 2013
To investigate the variations of mean platelet volume in patients with ischaemic cerebrovascular complaints, and to find out its diagnostic utility in an acute setting to help risk stratification in patients with ischaemic stroke and transient ischaemic attacks. The prospective cross-sectional study was conducted at the Gazi University Hospital, Ankara, ...
Haritova Aneliya - - 2013
Efflux transporters belonging to the family of ABC transporters have an important functional role in the maintenance of the intestinal barrier. As efflux transporters they prevent the absorption of toxic substances from feed, while at the same time facilitating the excretion of metabolic waste products as well as drugs from ...
Tariot Pierre N - - 2013
Diagnosing Alzheimer's disease (AD) is a multistep process, but an early diagnosis can help patients begin treatment as soon as possible to help slow cognitive and functional decline. To comprehensively evaluate patients with suspected dementia, physicians should obtain a thorough patient history with informant reports, complete a mental status exam, ...
Felice Alfons K G AK Department of Food Science and Technology, Vienna Institute of Biotechnology, BOKU-University of Natural Resources and Life Sciences, Muthgasse 11/1/56, Vienna, - - 2013
Electrochemical sensors for glucose monitoring employ different signal transduction strategies for electron transfer from the biorecognition element to the electrode surface. We present a biosensor that employs direct electron transfer and evaluate its response to various interfering substances known to affect glucose biosensors. The enzyme cellobiose dehydrogenase (CDH) was adsorbed ...
Tas Faruk - - 2013
The synergistic effects of new generation chemotherapeutics when combined with cisplatin have encouraged the development of new triplet combination regimens in the treatment of advanced non-small cell lung cancer (NSCLC). The aim of this study was to evaluate the feasibility of triplet chemotherapy using weekly cisplatin-gemcitabine-docetaxel (CGD) for patients with ...
Salatino Mariana - - 2013
Novel therapeutic strategies are needed to counteract breast cancer-associated immunosuppression. Silencing the expression of galectin-1 in a breast carcinoma model inhibited tumor growth and prevented lung metastasis by reducing the frequency and immunosuppressive activity of CD4(+)CD25(+) FOXP3(+) regulatory T cells.
Zhang Jun - - 2013
The aim of this study was to investigate the abnormal expression of a disintegrin and metalloproteinase-9 (ADAM9) in human resected non-small cell lung cancer (NSCLC) tissue, in order to evaluate the significance of ADAM9 expression in surgically resected NSCLC. Sixty-four cases of completely resected stage I NSCLC with mediastinal N2 ...
Unalan Demet - - 2013
To assess the sleeping habits of primary school children and establish link between sleeping hours and academic achievement. The cross-sectional study was conducted between April and June 2007, involving 2422 students of 6-8th grades in 12 primary schools located in Kayseri, Turkey. A questionnaire was presented to the students on ...
Saha Kalyan B - - 2013
Background and objectives: Tribal men's reluctance in sharing responsibilities as supportive partners in reproductive and sexual health matters debar women from their sexual rights coupled with their negligence in health care and lesser utilization of reproductive health facilities. As a matter of fact a large proportion of ill health particularly ...
Jangam Sujit R SR Abbott Diabetes Care Inc., 1360 South Loop Rd., Alameda, CA 94502, - - 2013
In a hospital setting, glucose is often measured from venous blood in the clinical laboratory. However, laboratory glucose measurements are typically not available in real time. In practice, turn-around times for laboratory measurements can be minutes to hours. This analysis assesses the impact of turn-around time on the effective clinical ...
Ksepka Daniel T DT Department of Marine, Earth and Atmospheric Sciences, North Carolina State University, Raleigh, NC 27695, USA. - - 2013
A feathered specimen of a new species of Eocypselus from the Early Eocene Green River Formation of Wyoming provides insight into the wing morphology and ecology in an early part of the lineage leading to extant swifts and hummingbirds. Combined phylogenetic analysis of morphological and molecular data supports placement of ...
Hamdy Nehal A - - 2013
The reaction of acid hydrazides (1a-c) with 2-chloro-1-(4-chlorophenyl)ethanone (2a) or 2-bromo-1-(4-bromophenyl)ethanone (2b) afforded bis-hydrazones 6a-d, while the reaction of la-c with 2-oxo-N-arylpropanehydrazonoyl chlorides (3a,b) furnished N-(aryl)propanehydrazonoyl chlorides 8a-c. The reaction of the latter chlorides with sodium benzenesulfinate furnished sulfones 11a-c. On the other hand, treatment of benzothiazole-2-carbohydrazide (1c) with the ...
Zhang Lian-Dong - - 2013
To investigate the characteristics of sexual development and sex hormone levels in obese male adolescents. We included 156 obese male adolescents with micropenis and microorchidia in an observation group and 50 healthy ones in a control group. We measured the body mass index (BMI), penile natural length and testicular volume, ...
Khan Majida - - 2013
Approximately 10-15% of the married couples remain childless. Conventional in vitro fertilisation (IVF) has been the treatment option for most of these cases. However, it is expensive and only available to a small fraction of the infertile population. The Sindh Institute of Reproductive Medicine (SIRM), Karachi, Pakistan, has introduced a ...
Hara Yu - - 2013
A 62-year-old man was suffering from bronchial asthma and referred to our institution with dry cough and dyspnea on exertion in November, 2010. He was diagnosed with eosinophilic granulomatosis with polyangiitis (EPGA, formerly Churg-Strauss syndrome) by chest radiographic findings, blood eosinophilia, mononeuritis multiplex and cardiomyopathy. Steroid therapy was started and ...
Kuran Bozena - - 2013
In the present paper, we describe proapoptotic activity of several heterocyclic compounds 9, 12, 18, 19 and 20 possessing succinimide (as well as succinimide related) moieties. The compounds properties were examined with the aid of flow cytometry on the promyelocytic leukemia cell line HL-60. The highest proapoptotic activity exhibited compound ...
Ye Feng - - 2013
To investigate father-to-infant transmission of hepatitis B virus (HBV) by detecting HBV mRNA in the IVF embryos with paternal HBV infection. We collected 18 discarded IVF embryos (9 cases) with paternal chronic HBV infection, and detected HBV mRNA in the embryos by single-cell RT-PCR. HBV mRNA positive signals were found ...
Nelas Paula - - 2013
Teenagers are a priority intervention group in sexual education. To promote a model of training intervention based on the debate and critical reflection about sexuality in the context of the classroom, to test its efficiency and characterize teenagers in the sexual context. It is a field experimental study with a ...
Tomczyk Michał - - 2013
Potentilla L. (Rosaceae) species have been used in traditional medicine in Asia, Europe and Northern America. This study analyzed the biological activity of aqueous extracts of Potentilla species (Rosaceae): Dasiphora fruticosa (syn. P. fruticosa), P. norvegica, P. pensylvanica, P. thuringiaca, P. crantzii and P. nepalensis. The activities were tested using ...
Yang Rui-Feng - - 2013
The study on stem cells is a hot field in biomedical science in recent years, and has furthered from laboratory to clinical application. Stem cells, according to their developmental stage and differential properties, can be divided into embryonic stem cells, induced PS cells and adult stem cells, among which, adult ...
Conrad Curdin - - 2013
Tumor-infiltrating plasmacytoid dendritic cells (pDCs) have been associated with poor patient prognosis. We have recently uncovered the ability of pDCs to activate and expand a subset of tumor-infiltrating FOXP3(+) regulatory T cells that express inducible costimulator (ICOS), providing new insights into the mechanisms that govern the escape of cancer from ...
Olejniczak Agnieszka B - - 2013
Methods for the modification of ganciclovir (GCV), acyclovir (ACV), cidofovir (CDV) and valganciclovir (VCDV) with boron cluster have been developed. Toxicity of the new derivatives was evaluated in adherent cells; no cytotoxicity was observed in five different cell lines up to 1000 microM with the exception of modified valganciclovir which ...
Yan Xing-Ke - - 2013
To observe the changes of inflammatory cytokines in autoimmune prostatitis (AIP) rats treated by electro-acupuncture (EA) at Sanyin points. We selected 40 Wistar male rats in this study, 10 as normal controls, and the other 30 made AIP models by intradermal injection of protein purification liquid from the prostate of ...
Khan Mohammed Yasin - - 2013
Rhodococcus equi has emerged as a serious pathogen in immunocompromised patients, including solid organ transplant recipients. Primary pulmonary involvement is the most common presentation. However, this opportunistic pathogen is often not considered in the differential diagnosis of pneumonia in transplant recipients. Furthermore, in cultures, Rhodococcus can be misinterpreted by microbiologists ...
Fonteneau Jean-François - - 2013
Attenuated measles viruses (MV) are assessed in clinical trials for their capacity to preferentially infect and kill tumor cells. We recently showed that MV-infected tumor cells are able to activate tumor antigen cross-presentation by myeloid and plasmacytoid dendritic cells. Thus, MV-based antitumor virotherapy may stimulate antitumor immune response.
Kędzia P - - 2013
In this paper we use a simple analysis based on properties of the axial field generated by symmetrical multipoles to reveal all possible distributions of two coaxial pairs of circular windings, which result in systems featuring zero octupole and 32 pole magnetic moments (six-order systems). Homogeneity of magnetic field of ...
Tuo Ying - - 2013
To explore the P75NTR expression in the mouse testis and its relationship with nestin. We observed the location of the expressions of P75NTR and nestin in the testis of the nestin-GFP transgenic mouse on postnatal day (PND) 5, 14 and 30 using immunofluorescence, and detected the expression levels of P75NTR ...
Campe Amely - - 2013
This study was to identify risk factors for bovine spongiform encephalopathy (BSE) by means of individual case-control data. 43 BSE cases in a defined region in Lower Saxony and Schleswig-Holstein were compared with 84 control animals. Purchase of new breeding stock and cross contamination between feed on the farm did ...
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