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Nadeem Erum E New York University. - - 2013
In response to national efforts to improve quality of care, policymakers and health care leaders have increasingly turned to quality improvement collaboratives (QICs) as an efficient approach to improving provider practices and patient outcomes through the dissemination of evidence-based practices. This article presents findings from a systematic review of the ...
Wang Ningli - - 2013
Previous experimental and clinical investigations have suggested that some patients with primary open-angle glaucoma may have an abnormally low orbital cerebrospinal fluid pressure (CSFP). A meta-analysis of available clinical data showed a marked overlap in lumbar CSFP measurements between patients with normal-tension glaucoma and healthy subjects, so that the question ...
Miller Marlene - - 2013
Children's hospitals represent a significant opportunity to reduce morbidity, mortality, and costs, particularly for children with complex chronic conditions (CCCs) who comprise a disproportionate and growing share of admissions, readmissions, and resource use. Most children with CCCs are in some way associated with a children's hospital, and the subspecialists who ...
d'Udekem Yves - - 2013
Remarkable outcomes have been reported after prolonged mechanical circulatory support in the pediatric population, but there is yet no clear delineation of the duration beyond which supporting a child becomes futile. The likelihood of survival in patients supported on extracorporeal membrane oxygenation for respiratory failure decreases with the length of ...
Pinares-Patiño C S - - 2013
The objective of this study was to determine the genetic parameters of methane (CH4) emissions and their genetic correlations with key production traits. The trial measured the CH4 emissions, at 5-min intervals, from 1225 sheep placed in respiration chambers for 2 days, with repeat measurements 2 weeks later for another ...
Dalton Heidi J - - 2013
The field of extracorporeal support is moving forward rapidly. New technology, improved experience with a variety of patients, and successful outcomes in groups previously excluded from extracorporeal life support are increasing the use of this technique in patient support. Although initial reports of outcome are encouraging, they are often taken ...
Tirali R E - - 2013
AIM The aim of this study was to investigate the effect of two antierosive pastes, Pronamel and Tooth Mousse Plus, on surface roughness of two composite (Filtek Supreme Ultra Universal Restorative and TPH Spectrum Restorative), one compomer (Dyract Extra), and two conventional glass ionomer restorative materials (Ionofil U and SDI) ...
O'Seaghdha Maghnus - - 2013
Group A Streptococcus (Streptococcus pyogenes or GAS) causes pharyngitis, severe invasive infections, and the post-infectious syndromes of glomerulonephritis and rheumatic fever. GAS can be internalized and killed by epithelial cells in vitro, a process that may contribute to local innate defense against pharyngeal infection. Secretion of the pore-forming toxin streptolysin ...
Slotwiner David - - 2013
Demographic and technological changes are driving increased utilization of cardiac implantable electronic devices (CIEDs) remote monitoring. In the USA, fee-for-service model of healthcare delivery, services rendered are valued based upon time, intensity, and technical or practice expense costs. As a consequence of this perspective, and to contain spending, Medicare has ...
Ricci Renato Pietro - - 2013
Remote monitoring of cardiac implantable electronic devices improves device surveillance and patient clinical management. The greatest challenge in implementing remote monitoring in standard practice is the need to develop new organizational models, capable of combining clinical effectiveness, low resource consumption, and patient acceptance. Since 2005, we developed a new model ...
Taylor Mark R - - 2013
Small bowel obstruction (SBO) is a clinical condition that is often initially diagnosed and managed in the emergency department (ED). The high rates of potential complications that are associated with an SBO make it essential for the emergency physician (EP) to make a timely and accurate diagnosis. The primary objective ...
Nchoutmboube Jules A - - 2013
All positive strand (+RNA) viruses of eukaryotes replicate their genomes in association with membranes. The mechanisms of membrane remodeling in infected cells represent attractive targets for designing future therapeutics, but our understanding of this process is very limited. Elements of autophagy and/or the secretory pathway were proposed to be hijacked ...
Ricci Renato Pietro RP Department of Cardiology, San Filippo Neri Hospital, Via Martinotti 20, Rome, Italy. - - 2013
Device-detected atrial fibrillation (AF) episodes predict poor clinical outcome regardless of symptoms. Potential benefits of remote monitoring are early arrhythmia detection and patient continuous monitoring. Several studies of device remote monitoring consistently demonstrated that AF represents the most common clinical alert and that detailed information on arrhythmia onset, duration, and ...
Lee S H - - 2013
AIM Pain control, which is necessary during most dental procedures, is administered by injecting a local anaesthetic. Because the injection itself can be painful, the procedure via which pain is reduced warrants continued investigation. Only a few studies regarding the reaction of children to dental needle insertion without the use ...
Tosini Gianluca G Circadian Rhythms and Sleep Disorders Program, Neuroscience Institute, Morehouse School of Medicine; Atlanta, GA, - - 2013
Melatonin in the mammalian eye is synthesized by the photoreceptors and its levels show a clear daily pattern with high levels at night and lower levels during the day. It is synthesized in the ciliary body and secreted into the aqueous humor with a pattern similar to what has been ...
Küllmer A - - 2013
History: A 71-year-old man with Richter's syndrome (transformation of chronic lymphocytic leukemia [CLL] to diffuse large B-cell lymphoma) was admitted to our hospital to get his second cycle of rituximab/bendamustin treatment. He had been diagnosed with Richter's syndrome three months earlier: a bulky tumor was seen on the backside of ...
Hirobe Megumi M Department of Urology, Sapporo Medical University, Sapporo, - - 2013
Xp11 translocation renal cell carcinoma is a rare disease diagnosed in children and adolescents in the advanced stage with an aggressive clinical course. Various gene fusions including the transcription factor E3 (TFE3) gene located on chromosome X cause the tumor. We established an Xp11 translocation renal cell carcinoma cell line ...
Peters E M J - - 2013
Stress and skin-an inseparable pair, this is how many of our patients perceive it and even clinicians are willing to integrate psychosomatic aspects into their recommendations if nothing from the somatic repertoire provides sufficient treatment. How the stress reaches the skin however is still an enigmatic matter to most lay ...
Lucius-Hoene G - - 2013
of the study was to explore meaning and consequences for patients for having their illness experiences published in the internet. Patients who participated in the establishment of a research-based internet website on illness experiences were interviewed about their experiences of taking part in the project.14 Patients with diabetes and 29 ...
Butt Warwick - - 2013
The clinical management of patients on extracorporeal membrane oxygenation should be standardized and follow clear guidelines or protocols. However, due to the diversity of cannulation strategies and the complex situations that extracorporeal membrane oxygenation is now used in, each extracorporeal membrane oxygenation program has developed its own clinical management strategies. ...
Cederberg C - - 2013
The last decade has seen an increase in environmental systems analysis of livestock production, resulting in a significant number of studies with a holistic approach often based on life-cycle assessment (LCA) methodology. The growing public interest in global warming has added to this development; guidelines for carbon footprint (CF) accounting ...
Bai Nan N Department of Immunology, School of Medicine, Nankai University, Tianjin, - - 2013
The yes-associated protein (YAP) transcription co-activator has been reported either as an oncogene candidate or a tumor suppressor. Liver tissue chips revealed that about 51.4% human hepatocellular carcinoma (HCC) samples express YAP and 32.9% HCC samples express phosphorylated YAP. In this study, we found that chemotherapy increased YAP protein expression ...
Pedroza Fernando - - 2013
Objectives Presentation and evaluation of results of the surgical technique of cervicofacial rhytidectomy used by the senior author (F.P.), using the classification of facial aging to determine the stage of pre- and postsurgical age.Methods The surgical technique was used in 1,181 patients operated on in the past 29 years, starting ...
Drosner M - - 2013
Local anaesthesia often is insufficient for more extensive procedures. Instead of general anaesthesia or sedation, pediatricians, gynaecologists and dentists increasingly use nitrous oxide (N2O). This study evaluates the suitability of this form of anesthesia in dermatology. In 24 patients (18 w, 6 m, mean age 49 y.) N2O/O2 inhalation (Livopan®) ...
Morgan William H - - 2013
The translaminar pressure gradient (TLPG) is largely influenced by the difference between intraocular pressure (IOP) and cerebrospinal fluid pressure (CSFP), but modulated by the buffering effect of orbital tissue and pia mater, which limits the reduction in retrolaminar tissue pressure as intracranial CSFP falls below 0 mm Hg. Across the ...
Fox Susannah - - 2013
Although the majority of US adults has Internet access and gathers health information online, the Internet does not replace clinicians. People rate health professionals as their top source for technical questions such as diagnosis and treatment, but nonprofessionals (eg, friends and family) are rated higher for emotional support and quick ...
Guerguerian Anne-Marie - - 2013
Setting up an extracorporeal life support program requires motivated experts, institutional commitment, and an interprofessional team of healthcare providers with dedicated time, space, and resources. This article provides guidance on the key steps involved in the process of developing a sustainable extracorporeal membrane oxygenation program, based on guidelines from the ...
Skuce P J - - 2013
Weather patterns in northern European regions have changed noticeably over the past several decades, featuring warmer, wetter weather with more extreme events. The climate is projected to continue on this trajectory for the foreseeable future, even under the most modest warming scenarios. Such changes will have a significant impact on ...
Monaco A - - 2013
AIM The aim of this study was to assess the dynamic activity of the mandible by means of a computerised kinesiograph in Class II patients treated with orthodontic therapy and to compare the results of this group with those of a sample of untreated Class II patients. METHODS Twenty young ...
Park Sook-Young - - 2013
Because most efforts to understand the molecular mechanisms underpinning fungal pathogenicity have focused on studying the function and role of individual genes, relatively little is known about how transcriptional machineries globally regulate and coordinate the expression of a large group of genes involved in pathogenesis. Using quantitative real-time PCR, we ...
Jonas Jost B - - 2013
Eyes with normal-tension and high-tension glaucoma can have a similar optic nerve head appearance, which differs markedly from the optic disc appearance in vascular optic neuropathies. Factors in addition to intraocular pressure (IOP) may play a role in the pathogenesis of glaucomatous optic neuropathy. Clinical and experimental studies have shown ...
Margolis Peter A PA James M. Anderson Center for Health Systems Excellence, Cincinnati Children's Hospital Medical Center, 3333 Burnet Ave, Cincinnati, OH 45229, USA. - - 2013
Despite significant gains by pediatric collaborative improvement networks, the overall US system of chronic illness care does not work well. A new paradigm is needed: a Collaborative Chronic Care Network (C3N). A C3N is a network-based production system that harnesses the collective intelligence of patients, clinicians, and researchers and distributes ...
Lequier Laurance L Stollery Children's Hospital, University of Alberta, Edmonton, AB, Canada. - - 2013
The extracorporeal membrane oxygenation circuit is made of a number of components that have been customized to provide adequate tissue oxygen delivery in patients with severe cardiac and/or respiratory failure for a prolonged period of time (days to weeks). A standard extracorporeal membrane oxygenation circuit consists of a mechanical blood ...
Subbarao G V - - 2013
Agriculture and livestock production systems are two major emitters of greenhouse gases. Methane with a GWP (global warming potential) of 21, and nitrous oxide (N2O) with a GWP of 300, are largely emitted from animal production agriculture, where livestock production is based on pasture and feed grains. The principal biological ...
Passariello C - - 2013
AIM To compare early bacterial adhesion and biofilm formation in vitro by different oral streptococci on a variety of commercial brackets. METHODS Adhesion and biofilm formation in vitro of 6 Streptococcus spp. on 15 different commercial brackets, in standard culture medium and in human saliva were evaluated by the MTT ...
Yücel Yeni - - 2013
Many glaucoma patients continue to lose vision despite treatment to lower intraocular pressure. In addition to the loss of retinal ganglion cells in the eye, there is injury to major visual pathways of the brain along the retino-geniculo-cortical pathway. Evidence for this comes from both glaucoma models and glaucoma patients. ...
Chagunda M G G - - 2013
The objective of this review was to examine the application and relative efficiency of the proprietary hand-held Laser Methane Detector (LMD) in livestock production, with a focus on opportunities and challenges in different production systems. The LMD is based on IR absorption spectroscopy, uses a semiconductor laser as a collimated ...
Cunningham Rebecca M RM School of Public Health, University of Michigan, Ann Arbor, MI, USA. - - 2013
A recent study demonstrated the efficacy of the SafERteens intervention in reducing peer violence among adolescents presenting to the emergency department (ED). The objective of this study was to determine the efficacy of this ED-based brief intervention (BI) on dating violence 1 year following the ED visit among the subsample ...
Jurado José Roberto Parisi - - 2013
Patients are seeking healthier lives, and at the same time their concern about having a beautiful face and maintaining a youthful appearance over time has increased. Traditionally, surgeries based on tissue resection and resurfacing were the focus in facial rejuvenation. Over the last decade, minimally invasive procedures have expanded exponentially ...
Favero V - - 2013
BACKGROUND Scissor bite is a rare malocclusion that often leads to minor facial asymmetry. An orthodontic and orthopaedic correction is advisable in young patients to prevent subsequent temporomandibular diseases requesting maxillofacial intervention. CASE REPORT In this case report a 8-year-old girl in mixed dentition with unilateral left scissor bite was ...
Killer Hanspeter Esriel - - 2013
A compartment is a space or volume that is separated from its environment. The cause for separation can be manifold. It can be expressed as a difference [INCREMENT] in parameters, such as size, area, volume, color or pressure. The border of a compartment can be rigid or flexible (compliance). The ...
Lau Chu-Pak - - 2013
Remote monitoring of pacemakers and implantable cardioverter defibrillators (ICDs) has emerged as a tool to replace regular follow-up of such devices, and to detect hardware failure, arrhythmias, and heart failure decompensation. The Asia-Pacific region is a geographically diverse area, with widely different cardiac device implant rates and expertise. However, common ...
Berndt A - - 2013
The growing global demand for food of animal origin will be the incentive for countries such as Australia and Brazil to increase their beef production and international exports. This increased supply of beef is expected to occur primarily through on-farm productivity increases. The strategies for reducing resultant greenhouse gas (GHG) ...
Li Chenhong - - 2013
DNA hybridization capture combined with next generation sequencing can be used to determine the sequences of hundreds of target genes across hundreds of individuals in a single experiment. However, the approach has thus far only been successfully applied to capture targets that are highly similar in sequence to the bait ...
Finlay S - - 2013
In 2009, the National Confidential Enquiry into Patient Outcome and Death (NCEPOD) report identified significant deficiencies in the management of acute kidney injury (AKI) in hospitals in the UK. Many errors arose from failure to recognise patients with AKI and those at risk of developing AKI. Currently, there is no ...
Lannon Carole M - - 2013
Multiple gaps exist in health care quality and outcomes for children, who receive <50% of recommended care. The American Board of Pediatrics has worked to develop an improvement network model for pediatric subspecialties as the optimal means to improve child health outcomes and to allow subspecialists to meet the performance ...
Gillis Anne M - - 2013
This commentary highlights the benefits of remote device monitoring and explores some of the challenges implementation of this technology worldwide.
Annich Gail - - 2013
Extracorporeal life support applications have evolved considerably in recent years. However, the blood-biomaterial interface remains incompletely understood, and management of the acute inflammatory response and coagulation pathways continues to be challenging. At present, the gold standard for anticoagulation is unfractionated heparin. Since the inception of extracorporeal life support, the mainstay ...
Petersen S O - - 2013
Ongoing intensification and specialisation of livestock production lead to increasing volumes of manure to be managed, which are a source of the greenhouse gases (GHGs) methane (CH4) and nitrous oxide (N2O). Net emissions of CH4 and N2O result from a multitude of microbial activities in the manure environment. Their relative ...
Heaven Ben B Institute of Health and Society, Newcastle University, Newcastle upon Tyne NE2 4AX, - - 2013
The marked demographic change toward greater proportions of older people in developed nations poses significant challenges for health and social care. Several studies have demonstrated an association between social roles in later life and positive health and well-being outcomes. After retiring from work, people may lose roles that provide purpose ...
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