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Results 301 - 350 of 1170
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van Drunen Julia - - 2013
Nickel-based metallic foams are commonly used in electrochemical energy storage devices (rechargeable batteries) as both current collectors and active mass support. These materials attract attention as tunable electrode materials because they are available in a range of chemical compositions, pore structures, pore sizes and densities. This contribution presents structural, chemical, ...
Barnes D R DR Department of Public Health and Primary Care, Centre for Cancer Genetic Epidemiology, University of Cambridge, Cambridge, - - 2013
Pedigrees with multiple genotyped family members have been underutilised in breast cancer (BC) genetic-association studies. We developed a pedigree-based analytical framework to characterise single-nucleotide polymorphism (SNP) associations with BC risk using data from 736 BC families ascertained through multiple affected individuals. On average, eight family members had been genotyped for ...
Thompson Emily - - 2013
Liver transplant biopsies are routinely archived following formalin fixation and paraffin embedding and may provide an additional source of diagnostic information following transcriptomic biomarker analysis. This study was designed to compare gene transcription between resting and stressed biliary cells in culture, these cells after fixation and embedding and archival liver ...
Valverde Jose M - - 2013
We study in this paper the conversion of CaO-based CO2 sorbents when subjected to repeated carbonation-calcination cycles with a focus on thermally pretreated/doped sorbents. Analytical equations are derived to describe the evolution of conversion with the cycle number from a unifying model based on the balance between surface area loss ...
Giordano Salvatore - - 2013
Background:Antibacterial lavage with topical antibiotics may reduce the occurrence of capsular contracture (CC) in breast augmentation.Objectives:The authors investigate the efficacy of povidone-iodine combined with antibiotic irrigation in reducing the CC rate.Methods:The charts of 333 consecutive women who underwent cosmetic breast augmentation during 2 different periods (group A: 2004-2009, n = ...
Akkoc H - - 2013
The goal of this study was to investigate whether the combination of the Poly(ADP-ribose) polymerase inhibitor 5-aminoisoquinolinone (5-AIQ) and the Na+-H+ exchanger inhibitor zoniporide (ZN) provides increased protection against ischemia-reperfusion (I/R) injury. Rats were separated into 5 groups (n=8): Group 1: Control group, Group 2: I/R, Group 3: 5-AIQ, Group ...
Chiba Junya - - 2013
We propose linear end-to-end assemblies of short DNA duplexes based on β-cyclodextrin-adamantane complexation. The assembled duplexes exhibited increased Tm values compared with those of the corresponding natural hybrids. Competition experiments with external guest molecules showed a substantial decrease in Tm of the terminal modified duplexes, suggesting the viability of inter-duplex ...
Schriver Maria - - 2013
Anticorrosion and antioxidation surface treatments such as paint or anodization are a foundational component in nearly all industries. Graphene, a single-atom-thick sheet of carbon with impressive impermeability to gases, seems to hold promise as an effective anticorrosion barrier, and recent work supports this hope. We perform a complete study of ...
Ying Ge Tong - - 2013
AIMS AND OBJECTIVES.: To describe the level of knowledge, attitudes, and self-reported quality of practice in pain assessment among nurses of Mainland China and explore links with current hospital pain policy and continuing education. BACKGROUND.: Knowledge is necessary for skilled pain assessment among nurses. Little is currently known regarding knowledge, ...
Feeney Erin J - - 2013
Purpose: Transgenic manipulation of mouse physiology facilitates the preclinical study of genetic risk factors, neural plasticity, and reactive processes accompanying Alzheimer's disease. Alternatively, entorhinal cortex lesions (ECLs) model pathophysiological denervation and axonal sprouting in rat. Given reports of anatomical differences between the mouse and rat hippocampus, application of the ECL ...
Kapatai G G School of Cancer Sciences, Vincent Drive, University of Birmingham, Birmingham, - - 2013
Mutation of the RB1 gene is necessary but not sufficient for the development of retinoblastoma. The nature of events occurring subsequent to RB1 mutation is unclear, as is the retinal cell-of-origin of this tumour. Gene expression profiling of 21 retinoblastomas was carried out to identify genetic events that contribute to ...
Vestberg Daniel D Department of Medicine, NU-Hospital Organization, Sweden. - - 2013
To investigate the potential relationship between overweight, obesity, and severe obesity and the risk of hospitalization for heart failure (HF) in patients with type 1 diabetes. We studied patients with type 1 diabetes included in the Swedish National Diabetes Registry during 1998-2003, and they were followed up until hospitalization for ...
Di Alberti L - - 2013
Several experimental studies have been performed in order to evaluate the behavior of different types of biomaterials involved in the process of tissue and bone regeneration. The guided bone regeneration (GBR) principles are applied in the rebuilding of periodontal tissues, damaged by the periodontal inflammatory process. Since the introduction of ...
Takagi K K Department of Pathology and Histotechnology, Tohoku University Graduate School of Medicine, 2-1 Seiryo-machi, Aoba-ku, 980-8575 Sendai, - - 2013
Estrogens have important roles in ductal carcinoma in situ (DCIS) of the breast. However, the significance of presurgical aromatase inhibitor treatment remains unclear. Therefore, we examined intratumoral concentration of estrogens and changes of clinicopathological factors in DCIS after letrozole treatment. Ten cases of postmenopausal oestrogen receptor (ER)-positive DCIS were examined. ...
Matsuba Yuki - - 2013
Functional gene clusters, containing two or more genes encoding different enzymes for the same pathway, are sometimes observed in plant genomes, most often when the genes specify the synthesis of specialized defensive metabolites. Here, we show that a cluster of genes in tomato (Solanum lycopersicum; Solanaceae) contains genes for terpene ...
Ikai Saeko - - 2013
OBJECTIVE:To report on a patient who was successfully rechallenged with clozapine after perforation of the large intestine and pulmonary embolism post operatively, and provide a literature review on clozapine rechallenge.CASE SUMMARY:A 46-year-old Japanese man with treatment-resistant schizophrenia developed constipation and slight abdominal discomfort while taking clozapine 275 mg/day. He developed ...
Ozguner Ismet F - - 2013
Background/Purpose The aim of the study is to evaluate the diagnostic value of interleukin-6 (IL-6) level and neutrophil cluster of differentiation 64 (CD64) expression in diagnosis of acute appendicitis (AA).Methods A prospective controlled trail was performed. Children who were hospitalized with a diagnosis of right lower quadrant pain were our ...
Kong Ping P The Wilf Family Cardiovascular Research Institute, Department of Medicine Cardiology Albert Einstein College of Medicine, Bronx, New York, - - 2013
As a typical matricellular protein, thrombospondin (TSP)-1, binds to the structural matrix and regulates cellular behavior by modulating growth factor and cytokine signaling. Obesity and diabetes are associated with marked upregulation of TSP-1 in adipose tissue. We hypothesized that endogenous TSP-1 may play an important role in the pathogenesis of ...
Battista G - - 2013
The authors report a case of oral tuberculosis in a 38-year-old heavy cigarette smoker man. He showed a painful, non-healing ulc er with indurated borders of the lateral surface of the tongue. No tonsil or lymph node enlargement was also noted. The medical history was not significant for systemic disease. ...
Bertossi D - - 2013
Third molar displacement into the infratemporal fossa during a surgical extraction is a rare event. Nevertheless, because of the presence of several vascular and neurological trunks through the infratemporal fossa, a correct management of this unusual surgical complication is fundamental in order to avoid many potential serious side effects. In ...
Pillai Resmi R Center for Hypertension and Personalized Medicine, University of Toledo College of Medicine and Life Sciences, Toledo, Ohio, - - 2013
Interactions or epistasis between genetic factors may contribute to "missing heritability." While linkage analyses detect epistasis, defining the limits of the interacting segments poses a significant challenge especially when the interactions are between loci in close proximity. The goal of the present study was to isolate two such epistatic blood ...
Yao Tao - - 2013
Only the half of it: A modified intercalation-deintercalation strategy that takes advantage of the characteristic thermally induced phase transition of monoclinic VO2 has been developed for the preparation of ultrathin VO2 nanosheets. The resultant nanosheets exhibit half-metallic character and a temperature-dependent phase transition. The half-metallicity could lead to applications in ...
Guiard Julie - - 2013
Upgrading diagnostics: A universal antigen has been prepared for the detection of brucellosis caused by any Brucella species that express a smooth lipopolysaccharide. This nonasaccharide, which encompasses Brucella A- and M-antigenic determinants, is uniquely available only by chemical synthesis.
Lianidou E S - - 2013
Blood testing for circulating tumour cells (CTC) has emerged as one of the hottest fields in cancer research. CTC detection and enumeration can serve as a 'liquid biopsy' and an early marker of response to systemic therapy, whereas their molecular characterisation has a strong potential to be translated to individualised ...
Khara Basile B Manchester Institute of Biotechnology and Faculty of Life Sciences, University of Manchester, 131 Princess Street, Manchester M1 7DN, - - 2013
Biocatalytic propane production: structure-based engineering of aldehyde-deformylating oxygenase improves specificity for short- and medium-chain-length aldehydes and enhances the propane generation in whole-cell biotransformations. This presents new opportunities for developing biocatalytic modules for the production of volatile "drop-in" biofuels.
Favretto Filippo - - 2013
Human liver fatty acid binding protein (hL-FABP) has been reported to act as an intracellular shuttle of lipid molecules, thus playing a central role in systemic metabolic homeostasis. The involvement of hL-FABP in the transport of bile salts has been postulated but scarcely investigated. Here we describe a thorough NMR ...
Sun Jiaqiang - - 2013
Both blue light (BL) and auxin are essential for phototropism in Arabidopsis thaliana. However, the mechanisms by which light is molecularly linked to auxin during phototropism remain elusive. Here, we report that PHYTOCHROME INTERACTING FACTOR4 (PIF4) and PIF5 act downstream of the BL sensor PHOTOTROPIN1 (PHOT1) to negatively modulate phototropism ...
Grabowsky Jennifer A - - 2013
OBJECTIVE:To evaluate everolimus drug-drug and drug-food interactions, with an emphasis on patients with cancer.DATA SOURCES:Literature was accessed through PubMed (1990-March 2013) using Boolean combinations of the terms drug interactions, herb-drug interactions, food-drug interactions, everolimus, antineoplastic agents, hormonal, and breast neoplasms. In addition, reference citations from publications and the prescribing information ...
Shao Changzhun - - 2013
Self-assembly: A tweezer-type perylene bisimide (PBI) dyad self-assembles into a defined bimolecular complex composed of a quadruple PBI π stack with remarkable kinetic stability, which is unprecedented for π-stacked dye aggregates. These persistent supramolecular species are of considerable interest for the elucidation of functional properties of dye aggregates.
Choudhary Dhagla R - - 2013
Ondansetron, selective serotonin (5-HT3) receptor blocker, used in treating chemotherapy induced nausea and vomiting in cancer patients. Mouth dissolving films containing ondansetron were developed to have better onset and patients compliances. The drug content of prepared films was within 85% -115%. The film were stable for 4 months when stored ...
Rostami-Charati Faramarz - - 2013
An efficient synthesis of 1,3-oxathiolan-2-yliden derivatives is described via a simple reactions between CH-acids, CS2 and oxiranes in the presence of triethylamine at 70°C in water as the solvent. The mild reaction conditions and high yields of the products exhibit the good synthetic advantage of this method.
Tate Judith A JA Department of Psychiatry, CRISMA Center, Department of Critical Care Medicine, Pittsburgh, PA 15238, USA. - - 2013
Symptom communication is integral to quality patient care. Communication between patients and nurses in the intensive care unit (ICU) is complicated by oral or endotracheal intubation and fluctuating neurocognitive status or delirium. We report the (a) prevalence of delirium and its subtypes in non-vocal, mechanically ventilated, critically ill patients; (b) ...
Tran Steven S University of Toronto at Mississauga, Department of Cell and Systems Biology, - - 2013
The zebrafish has been proposed for the study of the effects of ethanol on the vertebrate brain. Behavioural tests have been successfully employed in the phenotypical characterization of these effects. However, the short scale (minute to minute) time course of ethanol induced changes of zebrafish behaviour has not been analyzed. ...
Sun Yuan - - 2013
BACKGROUND:: The regulation of gene expression in nociceptive pathways contributes to the induction and maintenance of pain sensitization. Histone acetylation is a key epigenetic mechanism controlling chromatin structure and gene expression. Chemokine CC motif receptor 2 (CXCR2) is a proinflammatory receptor implicated in neuropathic and inflammatory pain and is known ...
Choudhery Mahmood Saba - - 2013
MSCs can be isolated from adult sources such as bone marrow and adipose tissue. In contrast to these adult tissue sources, harvesting MSCs from cord tissue is a non-invasive procedure and poses no risk to the donor. Stem cell banks offer the opportunity to cryopreserve cord tissue as a source ...
Chen Yi-Jen YJ Department of Pediatrics, Chang Gung Children's Hospital, Chang Gung University, College of Medicine, Taoyuan, - - 2013
In Taiwan, clinical and microbiological data on acute otitis media (AOM) with spontaneous otorrhea in children are limited. We retrospectively collected data on children with AOM and spontaneous otorrhea between January 2011 and June 2012. Otorrhea samples were collected using sterile swabs and sent for cultures. Pathogens found were Streptococcus ...
Rada Tommaso - - 2013
Cells constitute one of the fundamental components of any cartilage tissue engineering approach. Adipose tissue derived stem cells (ASCs) have a promising future considering the abundance of this tissue in the human body, ease of harness, and the high number of stem cells that can be isolated from small amounts ...
Wanderer Jonathan P - - 2013
BACKGROUND:: The allocation of intensive care unit (ICU) beds for postoperative patients is a challenging daily task that could be assisted by the real-time detection of ICU needs. The goal of this study was to develop and validate an intraoperative predictive model for unplanned postoperative ICU use. METHODS:: With the ...
Chalil Madathil Kapil K 110 Freeman Hall, Department of Industrial Engineering, Clemson University, Clemson, SC 29634, United States. - - 2013
Ethical and legal requirements for healthcare providers in the United States, stipulate that patients sign a consent form prior to undergoing medical treatment or participating in a research study. Currently, the majority of the hospitals obtain these consents using paper-based forms, which makes patient preference data cumbersome to store, search ...
Hankosky Emily R ER Department of Psychology, University of Illinois at Urbana-Champaign, 731 Psychology Building MC-716, 603 East Daniel Street, Champaign, IL 61820, - - 2013
Drug use typically begins during adolescence, which is a period of ongoing neurobiological development that may confer heightened vulnerability to develop drug dependence. Previously, our lab has shown that amphetamine (AMPH)-induced deficits in a medial prefrontal cortex (mPFC)-sensitive working memory task are greater in rats exposed to the drug during ...
Musil Carol M CM Frances Payne Bolton School of Nursing, Case Western Reserve University, Cleveland, OH 44106, USA. - - 2013
Grandmothers living with grandchildren face stressors that may increase depressive symptoms, but cognitive-behavioral strategies, such as resourcefulness, may reduce the effects of stressors on mental health. This analysis examined the contemporaneous and longitudinal relationships among intra-family strain, resourcefulness, and depressive symptoms in 240 grandmothers, classified by caregiving status to grandchildren. ...
Guyer Autumn Chandler - - 2013
PURPOSE OF REVIEW: The use of anticholinergic medications is well established as maintenance therapy for chronic obstructive pulmonary disease (COPD). There is a growing interest in the use of anticholinergic medications in the treatment of moderate to severe asthma. The purpose of this review is to summarize the scientific evidence ...
Xia Zuping - - 2013
3'-O-Retinoyl-5-fluoro-2'-deoxyuridine (RFUdR) is a putative dual-acting, mutually-masking (DAMM) prodrug for the treatment of cancer. As part of the proof of principle for the DAMM concept, the concentrations of RFUdR and its post-hydrolysis active metabolites, 5-fluoro-2'-deoxyuridine (FUdR) and all-trans-retinoic acid (RA), were determined in plasma and selected tissues following either bolus ...
Scherf K Suzanne KS Department of Psychology, Center for Brain, Behavior & Cognition, and Social Science Research Institute, Penn State University, University Park, PA 16802, - - 2013
This article is part of a Special Issue "Puberty and Adolescence". A unique component of adolescent development is the need to master new developmental tasks in which peer interactions become primary (for the purposes of becoming autonomous from parents, forming intimate friendships, and romantic/sexual partnerships). Previously, it has been suggested ...
Bundgaard-Nielsen Morten - - 2013
BACKGROUND:: Early mobilization is important for postoperative recovery but is limited by orthostatic intolerance (OI) with a prevalence of 50% 6 h after major surgery. The pathophysiology of postoperative OI is assumed to include hypovolemia besides dysregulation of vasomotor tone. Stroke volume-guided fluid therapy, so-called goal-directed therapy (GDT), corrects functional ...
Chen Enfu - - 2013
This study reports the first death caused by a novel avian influenza A (H7N9) virus in Zhejiang Province, China. The patient had chronic hepatitis B and history of exposure to poultry. The patient initially complained of diarrhea and influenza-like symptoms on March 7 and 14 respectively. The disease progressed to ...
Garofalo Michela M Department of Molecular Virology, Immunology and Medical Genetics, Comprehensive Cancer Center, Ohio State University, Columbus, OH, USA. Electronic address: - - 2013
Despite substantial progress in understanding the cancer signaling network, effective therapies remain scarce due to insufficient disruption of oncogenic pathways, drug resistance and drug-induced toxicity. New and more creative approaches are therefore required for the treatment of cancer. MicroRNAs (miRNAs) are a family of small noncoding RNAs that regulate gene ...
Rollins Nigel - - 2013
PURPOSE OF REVIEW: In the past 5 years, research has identified antiretroviral drug interventions that significantly reduce HIV transmission through breastfeeding. This evidence is reflected in WHO guidelines that now recommend national health authorities to adopt a public health approach for HIV and infant feeding, namely to promote and support ...
Kerr Abigail L AL University of Texas at Austin, Psychology Department, 1 University Station, A8000, Austin, TX 78712, USA. - - 2013
Behavioral experience, in the form of skilled limb use, has been found to impact the structure and function of the central nervous system, affecting post-stroke behavioral outcome in both adaptive and maladaptive ways. Learning to rely on the less-affected, or non-paretic, body side is common following stroke in both humans ...
Dylag Katarzyna - - 2013
A growing body of experimental and clinical evidence supports the hypothesis that the intestinal microbiota markedly influences function and the structure of the mucosal lining. Intestinal microbiota can potentially cause damage to the mucosa either directly by releasing toxins or indirectly by causing a detrimental immune response. Probiotic bacteria have ...
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