Search Results
Results 401 - 450 of 2813
< 4 5 6 7 8 9 10 11 12 13 14 >
Liew Wendy K M WK Department of Neurology, Boston Children's Hospital, Harvard Medical School, Boston, USA and Neurology service, Department of Paediatric Medicine, KK Women's and Children's Hospital, - - 2013
Pediatric neuromuscular disorders comprise a large variety of disorders that can be classified based on their neuroanatomical localization, patterns of weakness, and laboratory test results. Over the last decade, the field of translational research has been active with many ongoing clinical trials. This is particularly so in two common pediatric ...
Padmanaba Michael - - 2013
Conventional biodiversity surveys play an important role in ensuring good conservation friendly management in tropical forest regions but are demanding in terms of expertise, time, and budget. Can local people help? Here, we illustrate how local knowledge can support low cost conservation surveys. We worked in the Malinau watershed, East ...
Abràmoff Michael D MD Institute for Vision Research, University of Iowa, Iowa City, IA 52242, - - 2013
Best disease is a macular dystrophy caused by mutations in the BEST1 gene. Affected individuals exhibit a reduced electro-oculographic (EOG) response to changes in light exposure and have significantly longer outer segments (OS) than age-matched controls. The purpose of this study was to investigate the anatomical changes in the outer ...
Alçada-Morais Sofia - - 2013
The human ejaculate contains subpopulations of sperm with distinct properties. Human X- and Y-bearing sperm were separated with fluorescence activated cell sorting. To avoid the use of UV light the quantitative DNA dyes DRAQ5® and Dyecycle™ Vybrant® Violet were used. Sorting efficiency was similar for both dyes, but lower than ...
Vaclavik Lukas - - 2013
An ultra-high performance liquid chromatography-tandem mass spectrometry (UHPLC-MS/MS) method for determination of 34 mycotoxins in dietary supplements containing green coffee bean (GCB) extracts was developed, evaluated and used in analysis of 50 commercial products. A QuEChERS-like procedure was used for isolation of target analytes from the examined matrices. Average recoveries ...
Coyne Claire A CA cavoyne@indiana.eduIndiana University, Bloomington, IN 47405, - - 2013
Teenage motherhood is associated with poor offspring outcomes but these associations may be influenced by offspring birth year because of substantial social changes in recent decades. Existing research also has not examined whether these associations are due to the specific effect of mother's age at childbirth or factors shared by ...
Sheehan Bart - - 2013
OBJECTIVE Research on inpatient psychiatric care has paid little attention to the built environment of psychiatric wards. This study described the built environment in a sample of inpatient psychiatric wards in England and investigated relationships between staff satisfaction with the built environment of the ward and objective design features of ...
Kapp Julie M - - 2013
Abstract Scientists have estimated that approximately half of all deaths in the United States are attributed to largely preventable behaviors and exposures, such as tobacco use, diet and physical activity, and alcohol consumption. These findings are similar to reflections reported more than 100 years ago by public health authorities. Is ...
Godfrey Anna L AL Cambridge Institute for Medical Research and Department of Haematology, University of Cambridge, Cambridge, - - 2013
Subclones homozygous for JAK2V617F are more common and larger in patients with polycythemia vera compared to essential thrombocythemia, but their role in determining phenotype remains unclear. We genotyped 4564 erythroid colonies from 59 patients with polycythemia vera or essential thrombocythemia to investigate whether the proportion of JAK2V617F -homozygous precursors, compared ...
Lin Jintian - - 2013
We report on fabrication of whispering-gallery-mode microlasers in a Nd:glass chip by femtosecond laser three-dimensional micromachining. The main fabrication procedures include the fabrication of freestanding microdisks supported by thin pillars by femtosecond laser ablation of the glass substrate immersed in water, followed by CO<sub>2</sub> laser annealing for surface smoothing. The ...
Ruscher Karsten K Laboratory for Experimental Brain Research, Division of Neurosurgery, Department of Clinical Sciences, Lund University, Lund, Sweden. - - 2013
After stroke, brain inflammation in the ischemic hemisphere hampers brain tissue reorganization and functional recovery. Housing rats in an enriched environment (EE) dramatically improves recovery of lost neurologic functions after experimental stroke. We show here that rats housed in EE after stroke induced by permanent occlusion of the middle cerebral ...
Zhang Mei - - 2013
Some racemates including alcohol, ketone, flavone, phenol, base, and amide racemates etc. were successfully separated by using a 3D chiral nanoporous metal-organic framework (MOF) as a new chiral stationary phase in HPLC. The experimental results show that the chiral MOF possesses excellent recognition ability for various racemates, and indicate that ...
Mathot K J KJ Evolutionary Ecology of Variation Group, Max Planck Institute for Ornithology, Seewiesen, Germany. - - 2013
Quantitative genetic analyses of basal metabolic rate (BMR) can inform us about the evolvability of the trait by providing estimates of heritability, and also of genetic correlations with other traits that may constrain the ability of BMR to respond to selection. Here, we studied a captive population of zebra finches ...
Eo Moonjung - - 2013
Rayleigh scattering spectra of high-index {730} elongated tetrahexahedral gold nanoparticles and low-index {100}, {110}, and {111} gold nanorods were collected in real time in the reduction of 4-nitrophenol. The high-index facets are capable of accepting electrons seven times faster and emitting electrons two-and-a-half times faster than low-index facets.
Dalton Derek M DM Department of Chemistry, Colorado State University , Ft. Collins, Colorado 80523, United - - 2013
The Rh(I)•CKphos catalyzed [2 + 2 + 2] cycloaddition of 1,1-disubstituted alkenyl isocyanates and alkyl alkynes selectively forms previously inaccessible vinylogous amide indolizidinone cycloadducts, establishing an aza-quaternery stereocenter with excellent enantioselectivities (up to 98% ee). This advance enables a seven step catalytic, asymmetric synthesis of the tricyclic core of the ...
Daudén María I MI Department of Macromolecular Structure, Centro Nacional de Biotecnología, Consejo Superior de Investigaciones Científicas, 28049 Madrid, - - 2013
During bacteriophage morphogenesis DNA is translocated into a preformed prohead by the complex formed by the portal protein, or connector, plus the terminase, which are located at an especial prohead vertex. The terminase is a powerful motor that converts ATP hydrolysis into mechanical movement of the DNA. Here, we have ...
Djebbari Abdelghani - - 2013
Background In this paper, we developed a novel algorithm to detect the valvular split between the aortic and pulmonary components in the second heart sound which is a valuable medical information.Methods The algorithm is based on the Reassigned smoothed pseudo Wigner--Ville distribution which is a modified time--frequency distribution of the ...
Wang Yinghua - - 2013
BACKGROUND: The purpose of this study is to identify the risk factors for postoperative hypoxemia in patients with Stanford A aortic dissection surgery and their relation to clinical outcomes. METHODS: Clinical records of 186 patients with postoperative hypoxemia in Stanford A aortic dissection were analyzed retrospectively. The patients were divided ...
Arambula Diego D Department of Microbiology, Immunology, and Molecular Genetics, University of California, Los Angeles, CA 90095, - - 2013
Diversity-generating retroelements (DGRs) are a unique family of retroelements that confer selective advantages to their hosts by facilitating localized DNA sequence evolution through a specialized error-prone reverse transcription process. We characterized a DGR in Legionella pneumophila, an opportunistic human pathogen that causes Legionnaires disease. The L. pneumophila DGR is found ...
Li Kezhou - - 2013
OBJECTIVES: The study used a model of 90 % portal branch ligation (PBL) in rats to study the effect of losartan on portal vein pressure (PVP) and liver regeneration in rats after PBL. METHODS: A total of 144 male Sprague-Dawley rats were arbitrarily designated into three treatment method groups: a sham ...
Parajuli Ranjan - - 2013
BACKGROUND: Smoking is a recently established risk factor for colon cancer. We wanted to explore the hypothesis that women may be more susceptible to smoking-attributed colon cancer than men as one of the possible explanations for the high colon cancer risk of Norwegian women.METHODS: We followed 602,242 participants aged 19 ...
Kasnauskiene Jurate - - 2013
We report on a 15-year-old patient with hyperactivity, intellectual disability and severe speech developmental delay. An array CGH analysis revealed de novo 2q34 deletion, 958 kb in size, involving a single protein coding gene ERBB4 (position 212,505,294-213,463,152; NCBI build 36). The ERBB4 gene is important in numerous neurobiological processes in both ...
Wong Jacklyn - - 2013
BACKGROUND: Operational vector sampling methods lack standardization, making quantitative comparisons of malaria transmission across different settings difficult. Human landing catch (HLC) is considered the research gold standard for measuring human-mosquito contact, but is unsuitable for large-scale sampling. This study assessed mosquito catch rates of CDC light trap (CDC-LT), Ifakara tent ...
Tello Javier A - - 2013
The human GNRH receptor (GNRHR1) has a specific set of properties with physiological and pharmacological influences not appropriately modeled in laboratory animals or cell based systems. To address this deficiency we have generated human GNRHR1 knock-in mice and describe their reproductive phenotype. Measurement of pituitary GNRHR1 transcripts from homozygous human ...
Griewank Klaus - - 2013
PURPOSE: Conjunctival melanoma is a rare but potentially deadly tumor of the eye. Despite effective local therapies, recurrence and metastasis remain frequent. Once the tumor has metastasized, treatment options are limited and the prognosis is poor. To date, little is known of the genetic alterations in conjunctival melanomas. EXPERIMENTAL DESIGN: ...
Liem Franziskus - - 2013
This study combines functional and structural magnetic resonance imaging to test the "asymmetric sampling in time" (AST) hypothesis, which makes assertions about the symmetrical and asymmetrical representation of speech in the primary and nonprimary auditory cortex. Twenty-three volunteers participated in this parametric clustered-sparse fMRI study. The availability of slowly changing ...
Liu Hongzhuo - - 2013
Abstract A convenient and efficient in vitro diffusion cell method to evaluate formulations for inner ear delivery via the intratympanic route is currently not available. The existing in vitro diffusion cell systems commonly used to evaluate drug formulations do not resemble the physical dimensions of the middle ear and round ...
Polley Spencer D - - 2013
Background. Diagnosis of malaria relies on parasite detection by microscopy or antigen detection; both fail to detect low density infections. New tests providing rapid, sensitive diagnosis, with minimal need for training would enhance both malaria diagnosis and malaria control activities. We determined the diagnostic accuracy, in febrile returned travelers, of ...
Ding Li-Ping - - 2013
The geometries, electronic and magnetic properties of neutral and negatively charged Mn(coronene)m (M = V and Ti; n, m = 1, 2) complexes were investigated using density functional theory. The results show that one V or Ti atom prefers to occupy the η(6)-site in M(coronene)(0/-) complexes and to be sandwiched ...
Yang Jenny Y - - 2013
A nickel bis(diphosphine) complex containing pendant amines in the second coordination sphere, [Ni(PCy2Nt-Bu2)2](BF4)2 (PCy2Nt-Bu2 = 1,5-di(tert-butyl)-3,7-dicyclohexyl-1,5-diaza-3,7-diphosphacyclooctane), is an electrocatalyst for hydrogen oxidation. The addition of hydrogen to the NiII complex gives three isomers of the doubly protonated Ni0 complex [Ni(PCy2Nt-Bu2H)2](BF4)2. Using the pKa values and NiII/I and NiI/0 redox potentials ...
Kiernan Barbara - - 2013
Talk It Out was developed by speech-language pathologists to teach young children, especially those with speech and language impairments, to recognize problems, use words to solve them, and verbally negotiate solutions. One of the very successful by-products is that these same strategies help children avoid harming their voice. Across a ...
Reithinger Johannes H JH School of Biological Sciences, Seoul National University, Seoul 151-747, - - 2013
Nascent chains are known to be targeted to the endoplasmic reticulum membrane either by a signal recognition particle (SRP)-dependent co-translational or by an SRP-independent post-translational translocation route depending on signal sequences. Using a set of model and cellular proteins carrying an N-terminal signal anchor sequence of controlled hydrophobicity and yeast ...
Lúcio P S C - - 2013
BACKGROUND: Ameloblastic fibro-odontomas (AFO) are rare lesions and defined by the World Health Organisation as a tumour composed of a proliferation of odontogenic epithelium immersed in ectomesenchyme reminiscent of the interdental papilla. It also presents inductive processes leading to formation of enamel and dentine, confusing, histopathologically, with odontoma. Despite numerous ...
Perdivara Irina I Mass Spectrometry Group, NIH/National Institute of Environmental Health Sciences, Research Triangle Park, NC, USA. - - 2013
Collagens are the most abundant glycoproteins in the body. One characteristic of this protein family is that the amino acid sequence consists of repeats of three amino acids -(X-Y-Gly)n. Within this motif, the Y residue is often 4-hydroxyproline (HyP) or 5-hydroxylysine (HyK). Glycosylation in collagen occurs at the 5-OH group ...
Xu Fengguo - - 2013
Objective:Metabolic profiling of small molecules offers a snapshot of physiological processes. To identify metabolic signatures associated with type 2 diabetes and impaired fasting glucose (IFG) beyond differences in glucose, we used mass spectrometry-based metabolic profiling.Research Design and Methods:Individuals attending an institutional health screen were enrolled. IFG (n = 24) was ...
Chiarello Cynthia M - - 2013
STUDY DESIGN: Clinical measurement, concurrent validity criterion standard. OBJECTIVE: To determine the concurrent validity of digital nylon calipers in comparison to ultrasound imaging (USI) for the measurement of inter-recti distance (IRD). BACKGROUND: Diastasis rectus abdominis (DRA) is the abnormal increase in the width of the linea alba measured as IRD. ...
Green Christopher - - 2013
The prediction of risks posed by pharmaceuticals and personal care products in the aquatic environment now and in the future is one of the top 20 research questions regarding these contaminants following growing concern for their biological effects on fish and other animals. To this end it is important that ...
Li Ang - - 2013
Abstract Through primer walking method, the mitochondrial genome sequence of white croaker (Pennahia argentata) from Japanese coastal water was obtained in this study. The mitogenome length of Japanese white croaker was 16,486 bp. The genome contains 13 protein-coding genes, 2 ribosomal RNA genes, and 22 transfer RNA genes, a control region ...
Merc Matjaz - - 2013
INTRODUCTION: The method of free-hand pedicle screw placement is generally safe although it carries potential risks. For this reason, several highly accurate computer-assisted systems were developed and are currently on the market. However, these devices have certain disadvantages. We have developed a method of pedicle screw placement in the lumbar ...
Al-Yagon Michal - - 2013
The study examined the unique role of children's attachment with the father and with the mother, in explaining differences in internalizing features (i.e., loneliness, sense of coherence, hope and effort, and internalizing behavior syndrome) among 107 children with learning disabilities (LD) versus 98 children with typical development ages 8-12. Preliminary ...
Abdullayev Elshad - - 2013
Halloysite clay nanotubes loaded with corrosion inhibitors - benzotriazole (BTA), 2-mercaptobenzimidazole (MBI) and 2-mercaptobenzothiazole (MBT) were used as additives in self-healing composite paint coating of copper. These inhibitors form protective films on the metal surface and mitigate corrosion. Mechanisms involved in the film formation have been studied with optical and ...
Zhao Ying - - 2013
The gut microbiome is known to be extensively involved in human health and disease. In order to reveal the metabolic relationship between host and microbiome, we monitored recovery of the gut microbiota composition and fecal profiles of mice after gentamicin and/or ceftriaxone treatment. This was done by employing (1)H Nuclear ...
Banach Joanna - - 2013
OBJECTIVE: The study was designed to clarify the impact of short-term consumption of different types of alcoholic beverages on haemostatic factors, C-reactive protein (hsCRP) and endothelin-1 (E-1) plasma levels. METHODS: The study group consisted of 57 healthy male volunteers, aged 20-29 years. Subjects were randomized to consume 300 ml of ...
Pelletier Jennifer E - - 2013
To examine the association between college students' dietary patterns and frequency of purchasing food/beverages from campus area venues, purchasing fast food, and bringing food from home. Cross-sectional Student Health and Wellness Study. One community college and one public university in the Twin Cities, Minnesota. Diverse college students living off campus ...
Chai Liraz L Department of Microbiology and Immunobiology, Harvard Medical School, Boston, Massachusetts 02115, - - 2013
Biofilms are surface-associated groups of microbial cells that are embedded in an extracellular matrix (ECM). The ECM is a network of biopolymers, mainly polysaccharides, proteins, and nucleic acids. ECM proteins serve a variety of structural roles and often form amyloid-like fibers. Despite the extensive study of the formation of amyloid ...
Liu Wanyang W Department of Health and Environmental Sciences, Kyoto University Graduate School of Medicine, Yoshida Konoe, Sakyo, Kyoto, 606-8501, - - 2013
High consumption of soybean products has been associated with a reduced risk of hormone-sensitive tumors. Soybean products contain phytoestrogens, such as daidzein, and sesame seeds contain secoisolariciresinol. These compounds are further metabolized to equol, enterodiol, and enterolactone by intestinal bacteria. However, individual differences in the metabolizing potential remain unclear. The ...
Bose Sanjukta - - 2013
In this work we have done a detailed study of the influence of various parameters on spray coating of polymer films. Our aim is to produce polymer films of uniform thickness (500nm-1µm) and low roughness compared to the film thickness. The coatings are characterized with respect to thickness, roughness (profilometer) ...
Shaluei F - - 2013
The use of silver nanoparticles (Ag-NPs) is rapidly increasing, but there are limited data on their effects on the aquatic environment. The present study aimed to determine the acute toxicity and evaluate the effect of subacute concentrations of Ag-NPs (Nanocid®: average particle size of 61 nm) on hematological and plasma biochemical ...
Shima Fumiaki - - 2013
CpG oligodeoxynucleotide (ODN) encapsulated poly(γ-glutamic acid)-graft-L-phenylalanine ethylester (γ-PGA-Phe) nanoparticles (NPs) employing polycations were prepared to develop vaccine delivery and adjuvant systems. The CpG ODN was stably encapsulated into the NPs when protamine was used as the polycation. The CpG ODN-encapsulated γ-PGA-Phe NPs were taken up by macrophages and CpG ODN ...
Hodges Brian - - 2013
Since the 1970s, assessment of competence in the health professions has been dominated by a discourse of psychometrics that emphasizes the conversion of human behaviors to numbers and prioritizes high-stakes, point-in-time sampling, and standardization. There are many advantages to this approach, including increased fairness to test takers; however, some limitations ...
< 4 5 6 7 8 9 10 11 12 13 14 >