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Stagg John - - 2013
Triple-negative breast cancer (TNBC), as defined by the absence of estrogen receptor, progesterone receptor and human epidermal growth factor receptor 2 expression, is a challenging disease with the poorest prognosis of all breast cancer subtypes. Importantly, there are currently no known molecular targets for this subgroup of patients. Recent advances ...
Hodgins Justin L - - 2013
BACKGROUND: The current paradigm of arthroscopic training lacks objective evaluation of technical ability and its adequacy is concerning given the accelerating complexity of the field. To combat insufficiencies, emphasis is shifting towards skill acquisition outside the operating room and sophisticated assessment tools. We reviewed (1) the validity of cadaver and ...
Alvarez Santiago - - 2013
The distribution of distances from atoms of a particular element E to a probe atom X (oxygen in most cases), both bonded and intermolecular non-bonded contacts, has been analyzed. In general, the distribution is characterized by a maximum at short EX distances corresponding to chemical bonds, followed by a range ...
Stenström Pernilla - - 2013
Abstract Background: The necessity of referring adolescents with anorectal malformation (ARM) from pediatric units to adult care is unclear. The issue requires knowledge about the health of the adolescent. Objective: To examine the physical outcome, sexual health and quality of life (QoL) in adolescents with ARM. Methods: At medical counseling, ...
Darius H - - 2013
Atrial fibrillation is the most common form of cardiac arrhythmia with an age-dependent increase in prevalence. It is common clinical practice to treat patients with atrial fibrillation and who have a high risk for thromboembolic stroke with vitamin K antagonists. However, due to the many problems with vitamin K antagonist ...
Bleckmann Felix - - 2013
We demonstrate experimentally the manipulation of Airy surface plasmon beams in a linear potential. For this purpose, we fabricate dielectric-loaded plasmonic structures with a graded refractive index by negative-tone gray-scale electron beam lithography. Using such carefully engineered potentials, we show that the bending of an Airy surface plasmon beam can ...
Hayman John - - 2013
Charles Darwin's long-term illness has been the subject of much speculation. His numerous symptoms have led to conclusions that his illness was essentially psychogenic in nature. These diagnoses have never been fully convincing, however, particularly in regard to the proposed underlying psychological background causes of the illness. Similarly, two proposed ...
Ren Xiaoyuan - - 2013
A photonic crystal ring resonator (PCRR) of air hole arrays is fabricated on a silicon-on-insulator wafer by using electron-beam lithography and inductively coupled plasma etching. The designed PCRR is modeled and its performance is simulated by the two-dimensional finite difference time domain method. The simulation results show that the PCRR ...
Kutcher Stanley - - 2013
Mental disorders affect many young Canadians, and most do not access care, partly because of lack of health policy-driven programs and services. Recognizing this policy need, the Child and Youth Advisory Committee of the Mental Health Commission of Canada created Evergreen: A Child and Youth Mental Health Framework for Canada. ...
Zhao Na - - 2013
Although microRNAs (miRNAs) have been intensively studied in cardiac fibrosis, their roles in drug-mediated anti-fibrotic therapy are still unknown. Previously, Pioglitazone attenuated cardiac fibrosis and increased miR-711 experimentally. We aimed to explore the role and mechanism of miR-711 in pioglitazone-treated myocardial infarction in rats. Our results showed that pioglitazone significantly ...
Sodikoff Jamie B - - 2013
Endoscopic ultrasound (EUS) is a resource-intensive endoscopic procedure, but may result in high downstream health resource utilization and multispecialty impact. Our aim was to examine the downstream impact of EUS by specialty and by indication. A retrospective chart review was performed at an academic medical center for patients for whom ...
Wang Jing - - 2013
The increasing likelihood of silver nanoparticle (AgNP) releases to the environment highlights the importance of understanding AgNP interactions with plants, which are cornerstones of most ecosystems. In this study, poplars (Populus deltoides × nigra) and Arabidopsis thaliana were exposed hydroponically to nanoparticles of different sizes (PEG-coated 5 and 10 nm ...
Nikishkin Nicolai I - - 2013
Transition metal-catalyzed reactions are generally used for carbon-carbon bond formation on pyrazines and include, but are not limited to, classical palladium-catalyzed reactions like Sonogashira, Heck, Suzuki, and Stille reactions. Also a few examples of carbon-heteroatom bond formation in pyrazines are known. This perspective reviews recent progress in the field of ...
Bristow Jessica K - - 2013
Al2O3 changes from transparent to a range of intense colours depending on the chemical impurities present. In blue sapphire, Fe and Ti are incorporated; however, the chemical process that gives rise to the colour has long been debated. Atomistic modelling identifies charge transfer from Ti(iii) to Fe(iii) as being responsible ...
Nakamura Yoshiki - - 2013
This case report describes the significance of orthodontic treatment in reconstruction of a collapsed dental arch and a malocclusion associated with severe periodontitis. A Japanese man (age, 40 years 7 months) had an anterior crossbite, a collapsed occlusion, and severe periodontitis. Orthodontic treatment included the following steps: (1) correction of ...
Tong Van T - - 2013
We compared three measures of maternal smoking status--prepregnancy, during pregnancy, and smoking cessation during pregnancy-between the Pregnancy Risk Assessment Monitoring System (PRAMS) questionnaire and the 2003 revised birth certificate (BC). We analyzed data from 10,485 women with live births in eight states from the 2008 PRAMS survey, a confidential, anonymous ...
Kousin-Ezewu Onajite - - 2013
Alemtuzumab was first used in multiple sclerosis in 1991. It is a monoclonal antibody which is directed against CD52, a protein of unknown function on lymphocytes. Alemtuzumab causes a lymphopenia, following which homeostatic reconstitution leads to prolonged alteration of the immune repertoire. This reduces the risk of relapse and disability ...
Mairs Katie - - 2013
ABSTRACT Rates of HIV (human immunodeficiency virus) and sexual-risk behaviour for those aged 50 and over in the United States are highest and increasing in Florida, where many Canadian "snowbirds" winter. This pilot study examined the sexual-risk behaviour and predictors of HIV testing in a convenience sample of Canadian snowbirds ...
Kulkarni K - - 2013
Background: In the general surgical and anaesthetic literature, there has been a decline in research output originating from the UK. This study analysed the 10 globally leading and 2 UK leading otorhinolaryngology journals to determine whether this trend was also reflected within otorhinolaryngology. Methods: Citable research output was analysed from ...
Simão Tassiana Mesquita - - 2013
This case report describes the orthodontic treatment of an adult patient with iatrogenic absence of the maxillary canines, moderate maxillary and severe mandibular dental crowding, a Bolton discrepancy with a large mandibular anterior excess, a maxillary right lateral incisor crossbite, and Angle Class II molar relationships. The treatment consisted of ...
Fokoua Eric Numkam - - 2013
We formulate a simple model based on mass conservation to accurately predict the structural parameters of hollow-core photonic bandgap fibers from knowledge of the second stage preforms from which they are drawn. We show that combining this model with precalculated property maps can allow real-time prediction of the optical properties ...
Wang Tongzhou - - 2013
Detecting the existence of biomarkers is one of the most important issues in molecular diagnosis. This Letter presents a label-free decoding and detection method for biomarker tests based on hyperspectral imaging and interferometry. The decoding and detection results were extracted from a single hyperspectral image with different spectrum-to-thickness reconstructing algorithms, ...
Hered Robert W - - 2013
We determined the efficacy of pediatric-based preschool vision screening, as knowledge of vision screening effectiveness in primary care pediatrics is incomplete. Pediatricians and staff at nine primary care pediatric practices were trained in vision screening, and practices screened children aged 3-5 years from May 2007 through July 2008. Children failing ...
De Maeyer Catherine - - 2013
The syndrome of heart failure (HF) is a growing epidemic that causes a significant socio-economic burden. Despite considerable progress in the management of patients with HF, mortality and morbidity remain a major healthcare concern and frequent hospital admissions jeopardize daily life and social activities. Exercise training is an important adjunct ...
Ye Shengfa - - 2013
This perspective discusses the principles of the multistate scenario often encountered in transition metal catalyzed reactions, and is organized as follows. First, several important theoretical concepts (physical versus formal oxidation states, orbital interactions, use of (spin) natural and corresponding orbitals, exchange enhanced reactivity and the connection between valence bond and ...
Warner Digby F - - 2013
Fundamental aspects of the lifestyle of Mycobacterium tuberculosis Mycobacterium tuberculosis implicate DNA metabolism in bacillary survival and adaptive evolution. The environments encountered by M. tuberculosis during successive cycles of infection and transmission are genotoxic. Moreover, as an obligate pathogen, M. tuberculosis has the ability to persist for extended periods in ...
Jin Qi - - 2013
Non-obstructive azoospermia (NOA) is considered to be a severe infertility factor due to impaired spermatogenesis with the consequent absence of spermatozoa in the ejaculate. However, the underlying etiology and mechanism(s) remain elusive. The aim of this study was to investigate the mutation and association of single nucleotide polymorphisms (SNPs) of ...
Brannsether B - - 2013
Background/objectives:To establish new reference values for triceps (TSF) and subscapular (SSF) skinfolds of Norwegian children 4-16 years of age, and to define cutoff values for overweight and obesity using the criteria of the International Obesity Task Force (IOTF).Subjects/methods:A cross-sectional sample of 4606 children 4-16 years of age, part of a ...
Lyons Zaza - - 2013
OBJECTIVE The discipline of psychiatry, and psychiatry as a career option, have been negatively regarded by medical students for decades. There is a large amount of literature on attitudes of students and the factors that attract them to and detract from psychiatry. The aim of this article is to systematically ...
de Queiroz Sormani Bento Fernandes - - 2013
The use of bonded orthodontic molar tubes is becoming more prevalent in orthodontics because they have some advantages over conventional bonding. However, a bonded apparatus can become detached, leading to complications. This article presents the case of a submandibular-space abscess associated with a molar tube that detached during orthognathic surgery and ...
Kim S-J - - 2013
The timing of total hip replacement (THR) in patients with active tuberculosis (TB) of the hip is controversial, because of the potential risk of reactivation of infection. There is little information about the outcome of THR in these patients. We conducted a systematic review of published studies that evaluated the ...
Liu Zhengyong - - 2013
In this Letter, we reported on an ultrahigh birefringence photonic crystal fiber (PCF) with a germanium-doped elliptical core, which is fabricated in our lab using the stack-and-draw method. An ultrahigh birefringence of 1.1×10<sup>-2</sup> is obtained experimentally, which is close to the theoretical value of 1.4×10<sup>-2</sup> at the wavelength of 1550 nm. ...
Chen Xiaobo - - 2013
In this Letter, we reported on an interesting multiphoton infrared quantum cutting phenomenon in Yb<sup>3+</sup>Tb<sup>3+</sup>-doped oxyfluoride vitroceramics phosphors. From the study results it is found that the absorption of one 288.0 nm photon of the matrix results in the emission of two 975.5 nm photons of the Yb<sup>3+</sup> ion. In addition, it ...
Curtis Amy B - - 2013
To efficiently help communities prevent and manage diabetes, health departments need to be able to target populations with high risk but low resources. To aid in this process, we mapped county-level diabetes-related rates and resources/use using publicly available secondary data to identify Michigan counties with high diabetes prevalence and low ...
Driesen Peter - - 2013
The aim of this study was to evaluate the efficacy and tolerability of the combination of cisplatin-gemcitabine with concurrent thoracic radiotherapy for locally advanced non-small cell lung cancer (LA-NSCLC). This was a phase II, multicenter, open-label, single-arm trial in treatment-naïve patients with stage IIIA and IIIB LA-NSCLC. After three induction ...
Kapp Julie M - - 2013
Abstract Scientists have estimated that approximately half of all deaths in the United States are attributed to largely preventable behaviors and exposures, such as tobacco use, diet and physical activity, and alcohol consumption. These findings are similar to reflections reported more than 100 years ago by public health authorities. Is ...
Lin Jintian - - 2013
We report on fabrication of whispering-gallery-mode microlasers in a Nd:glass chip by femtosecond laser three-dimensional micromachining. The main fabrication procedures include the fabrication of freestanding microdisks supported by thin pillars by femtosecond laser ablation of the glass substrate immersed in water, followed by CO<sub>2</sub> laser annealing for surface smoothing. The ...
Ruscher Karsten - - 2013
After stroke, brain inflammation in the ischemic hemisphere hampers brain tissue reorganization and functional recovery. Housing rats in an enriched environment (EE) dramatically improves recovery of lost neurologic functions after experimental stroke. We show here that rats housed in EE after stroke induced by permanent occlusion of the middle cerebral ...
Zhang Mei - - 2013
Some racemates including alcohol, ketone, flavone, phenol, base, and amide racemates etc. were successfully separated by using a 3D chiral nanoporous metal-organic framework (MOF) as a new chiral stationary phase in HPLC. The experimental results show that the chiral MOF possesses excellent recognition ability for various racemates, and indicate that ...
Mathot K J - - 2013
Quantitative genetic analyses of basal metabolic rate (BMR) can inform us about the evolvability of the trait by providing estimates of heritability, and also of genetic correlations with other traits that may constrain the ability of BMR to respond to selection. Here, we studied a captive population of zebra finches ...
Eo Moonjung - - 2013
Rayleigh scattering spectra of high-index {730} elongated tetrahexahedral gold nanoparticles and low-index {100}, {110}, and {111} gold nanorods were collected in real time in the reduction of 4-nitrophenol. The high-index facets are capable of accepting electrons seven times faster and emitting electrons two-and-a-half times faster than low-index facets.
Underwood M - - 2013
Many older people living in care homes (long term residential care or nursing homes) are depressed. Exercise is a promising non-drug intervention for preventing and treating depression in this population. To evaluate the impact of a 'whole-home' intervention, consisting of training for residential and nursing home staff backed up with ...
Suszek Jarosław - - 2013
The experimental and numerical evaluation of the shadow effect in kinoform diffractive gratings for the terahertz (THz) range is given. This effect limits the diffractive efficiency of dense gratings, which are the base of the elements suited for convenient beam focusing and imaging in THz. The observed effect of redirecting ...
Tursch Marcus - - 2013
A growing number of individuals with significant medical histories travel for business and holidays. Precise anticipation and stratification of transport-relevant illness severity in the planning stage of an air medical evacuation is crucial for mission success and patient safety. We developed a staging system (ie, Stratification of Air Medical Transport ...
Khanduja V - - 2013
The FRCS (Tr & Orth) examination has three components: MCQs, Vivas and Clinical Examination. The Vivas are further divided into four sections comprising Basic Science, Adult Pathology, Hands and Children's Orthopaedics and Trauma. The Clinical Examination section is divided into Upper and Lower limb cases. The aim of this section ...
Castaman Giancarlo - - 2013
Von Willebrand disease is a common autosomal inherited bleeding disorder caused by quantitative or qualitative defects of von Willebrand factor, a multi-adhesive protein that binds platelets to exposed subendothelium and carries factor VIII in circulation. As a result of von Willebrand factor deficiency or abnormality, levels of factor VIII, the ...
Kulchin Y N - - 2013
Separate nanoholes with the minimum size down to 35 nm (∼λ/15) and nanohole arrays with the hole size about 100 nm (∼λ/5) were fabricated in a 50 nm optically "thick" Au/Pd film, using single 532 nm pump nanosecond laser pulses focused to diffraction-limited spots by a specially designed apertureless dielectric fiber probe. Nanohole fabrication ...
Zhu Yuanyuan - - 2013
Heterostructures and interfacial defects in a 40-nm-thick SrTiO3 (STO) film grown epitaxially on a single-crystal MgO (001) were investigated using aberration-corrected scanning transmission electron microscopy and geometric phase analysis. The interface of STO/MgO was found to be of the typical domain-matching epitaxy with a misfit dislocation network having a Burgers ...
Mackenzie Robert - - 2013
Simultaneous LSPR and electronic sensing of potential induced ion adsorption onto gold nanowire arrays is presented. The formation of a Stern layer upon applying an electrochemical potential generated a complex optical response. Simulation of a lossy atomic layer on the nanowire array using the Multiple Multipole Program (MMP) corresponded very ...
Reardon Claudia L - - 2013
OBJECTIVE Medical student interest groups across all specialties help students explore various specialties. There are no published reports on psychiatry student interest group (PSIG) curricula. The aim was to develop elements of a curriculum for such groups, based on data elicited from medical students and faculty members through a multi-institutional ...
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