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Melenka Garrett W - - 2013
Archwire rotation is used in orthodontic treatment to alter the labiolingual orientation of a tooth. Measurement of the 3-dimensional (3D) motion of the orthodontic brackets requires a new configuration of the orthodontic torque simulator. The orthodontic torque simulator was coupled with a stereo microscope and 2 cameras to allow for ...
Tang Hongchun - - 2013
Photoacoustic microscopy (PAM), whose image quality largely depends on the optical absorption of samples, provides endogenous information for structural and functional imaging. However, PAM technology in general can not provide edge enhancement imaging for absorbing objects. Therefore, PAM and differential microscopy are integrated for the first time in a single ...
Wang Meng - - 2013
Point mutations in human mitochondrial tRNAs (hmtRNAs) can cause various disorders such as chronic progressive external ophthalmoplegia (CPEO) and mitochondrial myopathy (MM). Mitochondrial tRNALeu , especially UUR isoacceptor is recognised as a hot spot for pathogenic mitochondrial DNA point mutations. Thus far, 40 mutations have been identified in hmtRNAsLeu. Here, ...
Flood Victoria M - - 2013
OBJECTIVE: A simple FFQ which ranks young children's dietary habits is necessary for population-based monitoring and intervention programmes. The aim of the present study was to determine the reliability and validity of a short FFQ to assess the dietary habits of young children aged 2-5 years. DESIGN: Parents completed a ...
Cheung Cs - - 2013
OBJECTIVE: To compare the psychological impact following early miscarriage between women who conceived naturally and women who conceived following assisted reproduction. DESIGN: Prospective cohort study. SETTING: Assisted reproduction clinic and general gynaecological unit in a university-affiliated, tertiary referral hospital. POPULATION: A cohort of 150 women (75 after natural conception; 75 ...
Ormondroyd Elizabeth - - 2013
Inherited cardiac conditions (ICCs) can lead to sudden cardiac death at any age, yet are often asymptomatic and clinically undetected. Prophylactic interventions are available and cascade testing is recommended to identify family members at risk. When a disease-causing mutation has been identified in a family, pre-symptomatic genetic testing (PSGT) is ...
Sheth Rushikesh - - 2013
Limb development relies on an exquisite coordination between growth and patterning, but the underlying mechanisms remain elusive. Anterior-posterior and proximal-distal specification initiates in early limb bud concomitantly with the proliferative expansion of limb cells. Previous studies have shown that limb bud growth initially relies on fibroblast growth factors (FGFs) produced ...
Moreno-Smith Myrthala M Department of Gynecologic Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, - - 2013
Chronic sympathetic nervous system activation results in increased angiogenesis and tumor growth in orthotopic mouse models of ovarian carcinoma. However, the mechanistic effects of such activation on the tumor vasculature are not well understood. Dopamine (DA), an inhibitory catecholamine, regulates the functions of normal and abnormal blood vessels. Here, we ...
Hung Yu-Han - - 2013
To distribute microwaves over fibers, optical single-sideband (SSB) modulation signals are preferred to optical double-sideband (DSB) modulation signals. This study investigates an optically injected semiconductor laser at period-one nonlinear dynamics for optical DSB-to-SSB conversion. For the operating microwave frequencies up to 40 GHz investigated in this study, the proposed system regenerates ...
Shimamura Munehisa M Brain and Mind Research Institute, Weill Cornell Medical College, New York, NY 10065, - - 2013
Cyclooxygenase-2-derived prostaglandin E2 (PGE2) contributes to excitotoxic and ischemic neuronal cell death by engaging neuronal PGE2 type 1 receptors (EP1R). Our previous studies have shown that EP1R signaling resulted in disturbances of intracellular Ca(2+) homeostasis and suppression of the pro-survival protein kinase AKT. The aim of this study was to ...
Woo Se Joon - - 2013
To investigate the relationship between cytokine levels in cord blood and perinatal factors and retinopathy of prematurity (ROP) in gestational age-matched, preterm, newborn infants. Each of 20 premature singleton infants with ROP (gestational age < 32 weeks) was matched for gestational age, birth weight, and sex with two control infants ...
Huang Kuo-Jien - - 2013
The phosphoenolpyruvate phosphotransferase system (PTS) is ubiquitous in eubacteria and absent from eukaryotes. The system consists of two phosphoryl carriers, enzyme I (EI) and the histidine-containing phosphoryl carrier protein (HPr), and several PTS transporters, catalyzing the concomitant uptake and phosphorylation of several carbohydrates. Since a deficiency of EI in bacterial ...
Peischl S S Section of Integrative Biology, University of Texas at Austin, Austin, TX, USA. - - 2013
Chromosomal inversions are common in natural populations and are believed to be involved in many important evolutionary phenomena, including speciation, the evolution of sex chromosomes and local adaptation. While recent advances in sequencing and genotyping methods are leading to rapidly increasing amounts of genome-wide sequence data that reveal interesting patterns ...
Schughart Klaus K 1] Department of Infection Genetics, Helmholtz Centre for Infection Research, 38124 Braunschweig, Germany [2] University of Veterinary Medicine Hannover, Germany [3] University of Tennessee Health Science Center, Memphis, TN, - - 2013
Experimental animal models are essential to obtain basic knowledge of the underlying biological mechanisms in human diseases. Here, we review major contributions to biomedical research and discoveries that were obtained in the mouse model by using forward genetics approaches and that provided key insights into the biology of human diseases ...
Pei Zhaohui - - 2013
The aim of the present study was to examine the effects of acute infrasound exposure on oxidative damage and investigate the underlying mechanisms in rat cardiomyocytes. Neonatal rat cardiomyocytes were cultured and exposed to infrasound for several days. In the study, the expression of CAT, GPx, SOD1, and SOD2 and ...
Rashid A - - 2013
Lateral clavicular physeal injuries in adolescents are frequently misinterpreted as acromioclavicular dislocations. There are currently no clear guidelines for the management of these relatively rare injuries. Non-operative treatment can result in a cosmetic deformity, warranting resection of the non-remodelled original lateral clavicle. However, fixation with Kirschner (K)-wires may be associated ...
Duina Andrea A AA Biology Department, Hendrix College, Conway, Arkansas 72032, USA. - - 2013
An article from Alan Hinnebusch's laboratory in the March 2013 issue of GENETICS establishes an exciting new link between proteins with well-established roles in the endomembrane system and the process of transcription elongation. This Primer article provides tools needed for students to fully appreciate, analyze, and critically evaluate the experiments ...
Kramann Rafael - - 2013
Parathyroid hormone-related protein (PTHrP) is a pleiotropic factor with multiple physiological functions in morphogenesis, cell proliferation, differentiation, apoptosis, and calcium homeostasis. In the kidney, PTHrP is known to be expressed abundantly and to be upregulated in various experimental nephropathies, showing growth-modulatory and proinflammatory properties. Ardura et al. demonstrate a possible ...
Ashrafi Reza - - 2013
We experimentally demonstrate a superluminal space-to-time mapping process in grating-assisted (GA) codirectional coupling devices, particularly fiber long period gratings (LPGs). Through this process, the grating complex (amplitude and phase) apodization profile is directly mapped into the device's temporal impulse response. In contrast to GA counterdirectional couplers, e.g., Bragg gratings, this ...
Cheng Hua - - 2013
We present a mid-IR highly tunable optical polarization converter composed of asymmetric graphene nanocrosses. It can convert linearly polarized light to circularly and elliptically polarized light or exhibit a giant optical activity at different wavelengths. The transmitted wavelength and polarization states can also be dynamically tuned by varying the Fermi ...
George Melissa - - 2013
OBJECTIVE School programs provided by the Substance Abuse and Mental Health Services Administration's National Registry of Evidence-Based Programs and Practices (NREPP) were reviewed to describe program characteristics, costs, and ratings of research and dissemination. METHODS Data were gathered from the NREPP to identify mental health programs adaptable for schools. Program ...
Zhang Hangxiao - - 2013
Brine shrimps, Artemia (Crustacea, Anostraca), inhabit hypersaline environments and have a broad geographical distribution from sea level to high plateaus. Artemia therefore possess significant genetic diversity, which gives them their outstanding adaptability. To understand this remarkable plasticity, we sequenced the mitochondrial genomes of two Artemia tibetiana isolates from the Tibetan ...
Boynton Wen - - 2013
Diverticulosis is one of the most common gastrointestinal conditions affecting the general population in the Western world. It is estimated that over 2.5 million people are affected by diverticular disease in the United States. The spectrum of clinical manifestations of diverticulosis ranges from asymptomatic diverticulosis to complicated diverticulitis. Treatment for ...
Ma Hongyan - - 2013
Methods for the detection of plasmid loss in natural environments have typically relied on replica plating, selective markers and PCR. However, these traditional methods have the limitations of low sensitivity, underestimation of specific cell populations, and lack of insightful data for non-homogeneous environments. We have developed a non-invasive microscopic analytical ...
Ooki Syuichi - - 2013
The purpose of the present study was to clarify the characteristics of fatal child maltreatment in families with multiple births in Japan. An exhaustive information search was performed to find multiple-birth cases between July 2003 and March 2011. There were 437 cases of fatal maltreatment of children aged 0-17 years ...
Zeybek Burak - - 2013
Abstract Aim: To investigate the possible roles of selected single nucleotide gene polymorphisms (SNPs) of the activin A receptor type 2A (ACVR2A) gene in the pathogenesis of preeclampsia. Methods: Ninety-four patients with preeclampsia and 166 healthy pregnant women were included in this study. Genomic DNA was extracted from venous blood ...
Dalto Joseph D - - 2013
Poor communication can result in adverse events. Presently, no standards exist for classifying and analyzing air medical communication errors. This study sought to determine the frequency and types of communication errors reported within an air medical quality and safety assurance reporting system. Of 825 quality assurance reports submitted in 2009, ...
Benedetti Valentini M - - 2013
Of 48 consecutive children with Gartland III supracondylar fractures, 11 (23%) had evidence of vascular injury, with an absent radial pulse. The hand was pink and warm in eight and white and cold in the other three patients. They underwent colour-coded duplex scanning (CCDS) and ultrasound velocimetry (UV) to investigate ...
Hersh Elliot V - - 2013
The authors evaluated the efficacy and tolerability of 10 percent and 20 percent benzocaine gels compared with those of a vehicle (placebo) gel for the temporary relief of toothache pain. They also assessed the compliance with the label dose administration directions on the part of participants with toothache pain. Under ...
Abboud Hanna E - - 2013
A recent clinical trial in patients with chronic kidney disease (CKD) and diabetic nephropathy demonstrated that bardoxolone methyl (CDDO-ME) increases estimated glomerular filtration rate (eGFR) by an unknown mechanism. The paper by Ding et al. suggests that short-term administration of a CDDO-ME analog increases GFR by increasing glomerular surface area. ...
Simsek Ergun - - 2013
A closed-form approximate expression for the optical conductivity of graphene is developed, which generates results with less than 0.8% maximum absolute error for λ>250  nm. The expression takes wavelength, temperature, chemical potential, and hopping parameter into account and provides a fast, easy, and reliable alternative to well-known methods that include singular ...
Luo Xin - - 2013
A high-uniformity multichannel plasmonic filter based on metal-insulator-metal (MIM) waveguide is proposed. It consists of two metal layers and sandwiched multiple insulator super units structured by alternately stacking two insulators with different refractive indices. By linearly lengthening the high refractive index insulators in each super unit, the dispersion-induced loss coefficient ...
Meesters Johannes Aj - - 2013
Engineered nanomaterials (ENMs) possess novel properties making them attractive for application in a wide spectrum of fields. These novel properties are not accounted for in the environmental risk assessment methods REACH proposes in their guidance on environmental exposure estimation, although ENMs are already applied in a variety of consumer and ...
Song Jie - - 2013
Monoclinic NaVOPO4 is explored as a cathode material for a sodium ion battery. It exhibits electrochemical activity operating at an average potential of 3.6 V (vs. Na(+)/Na) and delivers a reversible capacity of 90 mA h g(-1) at 1/15 C.
Ha Mi-Sun - - 2013
Abstract Using a stepwise assessment of the exposure of Korean consumers to acesulfame K and sucralose, theoretical maximum daily intakes of the sweeteners were calculated using the Budget screening method, which resulted in values greater than the acceptable daily intakes (ADIs). Accordingly, the daily intakes of the sweeteners based on ...
Günther K-P - - 2013
Increasing data are available describing risk factors for the development of local and systemic adverse events following operations using metal-on-metal (MoM) hip implants. The prevalence and clinical relevance of metal-associated problems are, however, still under debate. They can be influenced by type and position of implant as well as patient-specific ...
Lyons Zaza - - 2013
OBJECTIVE The discipline of psychiatry, and psychiatry as a career option, have been negatively regarded by medical students for decades. There is a large amount of literature on attitudes of students and the factors that attract them to and detract from psychiatry. The aim of this article is to systematically ...
de Queiroz Sormani Bento Fernandes - - 2013
The use of bonded orthodontic molar tubes is becoming more prevalent in orthodontics because they have some advantages over conventional bonding. However, a bonded apparatus can become detached, leading to complications. This article presents the case of a submandibular-space abscess associated with a molar tube that detached during orthognathic surgery and ...
Kim S-J - - 2013
The timing of total hip replacement (THR) in patients with active tuberculosis (TB) of the hip is controversial, because of the potential risk of reactivation of infection. There is little information about the outcome of THR in these patients. We conducted a systematic review of published studies that evaluated the ...
Liu Zhengyong - - 2013
In this Letter, we reported on an ultrahigh birefringence photonic crystal fiber (PCF) with a germanium-doped elliptical core, which is fabricated in our lab using the stack-and-draw method. An ultrahigh birefringence of 1.1×10<sup>-2</sup> is obtained experimentally, which is close to the theoretical value of 1.4×10<sup>-2</sup> at the wavelength of 1550 nm. ...
Chen Xiaobo - - 2013
In this Letter, we reported on an interesting multiphoton infrared quantum cutting phenomenon in Yb<sup>3+</sup>Tb<sup>3+</sup>-doped oxyfluoride vitroceramics phosphors. From the study results it is found that the absorption of one 288.0 nm photon of the matrix results in the emission of two 975.5 nm photons of the Yb<sup>3+</sup> ion. In addition, it ...
Curtis Amy B AB Western Michigan University, College of Health & Human Services, Interdisciplinary Health Sciences, Kalamazoo, MI 49008, USA. - - 2013
To efficiently help communities prevent and manage diabetes, health departments need to be able to target populations with high risk but low resources. To aid in this process, we mapped county-level diabetes-related rates and resources/use using publicly available secondary data to identify Michigan counties with high diabetes prevalence and low ...
Driesen Peter - - 2013
The aim of this study was to evaluate the efficacy and tolerability of the combination of cisplatin-gemcitabine with concurrent thoracic radiotherapy for locally advanced non-small cell lung cancer (LA-NSCLC). This was a phase II, multicenter, open-label, single-arm trial in treatment-naïve patients with stage IIIA and IIIB LA-NSCLC. After three induction ...
Burgut F Tuna - - 2013
OBJECTIVE To assure adequate treatment for patients with mental illness worldwide, medical schools must impart positive attitudes toward psychiatry. The authors examined the effect of culture on changes in attitudes toward psychiatry among medical students receiving the same psychiatry clerkship curriculum in two different countries. METHODS A group of 74 ...
Gøthesen O - - 2013
We evaluated the rates of survival and cause of revision of seven different brands of cemented primary total knee replacement (TKR) in the Norwegian Arthroplasty Register during the years 1994 to 2009. Revision for any cause, including resurfacing of the patella, was the primary endpoint. Specific causes of revision were ...
Buehler Andreas - - 2013
Multispectral optoacoustic tomography (MSOT) of functional and molecular contrast has the potential to find broad deployment in clinical practice. We have developed the first handheld MSOT imaging device with fast wavelength tuning achieving a frame rate of 50 Hz. In this Letter, we demonstrate its clinical potential by dynamically resolving multiple ...
Bonora S - - 2013
We present a beam characterization system for infrared lasers which can measure both wavefront and beam profile with visible detectors. While previous studies demonstrated the conversion from the visible to the near infrared, this device exploits the wavelength conversion from the infrared to the visible, which is based on the ...
Ma Yongchao - - 2013
Immunosenescence is described as a decline in the normal functioning of the immune system associated with physiologic ageing. Immunosenescence contributes to reduced efficacy to vaccination and increased susceptibility to infectious diseases in the elderly. Extensive studies of laboratory animal models of ageing or donor lymphocyte analysis have identified changes in ...
Stroet Anke - - 2013
Multiple sclerosis (MS)-related spasticity is associated with disability and impairment in quality of life. We report on a patient with secondary progressive MS and spastic tetraparesis (Expanded Disability Status Scale score 8.5). The right arm exhibited flexor spasticity resulting in functional disability despite multimodal symptomatic treatment. Intrathecal baclofen led to ...
Jadeja Shalini S MRC Human Genetics Unit, MRC Institute of Genetics & & Molecular Medicine, University of Edinburgh, Crewe Road, Edinburgh EH4 2XU, United - - 2013
A mouse mutant identified during a recessive N-ethyl-N-nitrosourea (ENU) mutagenesis screen exhibited ocular hemorrhaging resulting in a blood-filled orbit, and hence was named "redeye." We aimed to identify the causal mutation in redeye, and evaluate it as a model for diabetic retinopathy (DR). The causative gene mutation in redeye was ...
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