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Corrarino Jane E - - 2013
INTRODUCTION: This article describes the impact of health literacy on women's health and provides strategies for addressing this public health issue. METHODS: A comprehensive literature review was conducted of peer-reviewed journals. Multiple electronic databases were used, including CINAHL, MEDLINE, PubMed, and Google Scholar. Key words were used to identify articles ...
von Babo Michelle - - 2013
BACKGROUND AND PURPOSE: To compare potential risk factors, clinical symptoms, diagnostic delay, and 3-month outcome between spontaneous internal carotid artery dissection (sICAD) and spontaneous vertebral artery dissection (sVAD). METHODS: We compared patients with sICAD (n=668) and sVAD (n=302) treated in 3 university hospitals. RESULTS: Patients with sICAD were older (46.3±9.6 ...
Li Yingchao - - 2013
PURPOSE: To study the innate immunity in telomerase-immortalized human stroma fibroblasts (THSFs) challenged with Aspergillus fumigatus hyphae after co-pretreatment with TLR2 and TLR4 ligand. METHODS: THSFs were pretreated with different concentrations of zymosan and/or lipopolysaccharide (LPS) at different time periods, and challenged with high-dose Aspergillus fumigatus hyphae. The gene expression ...
Marinescu M - - 2013
PURPOSE: The purpose of this study was to introduce synchrotron radiation X-ray phase computed tomography (SR-PCT) as a new method of visualizing ultrasmall superparamagnetic particles of iron oxide (USPIO) distribution into the brains of mice with neuroinflammation. PROCEDURES: The sensitivity of the technique was assessed by performing back-to-back SR-PCT and ...
Li Ang - - 2013
Antimicrobial peptides from a wide range of amphibian species, especially frogs of the genus Rana, have been characterised and are potential therapeutic agents. Here we describe the isolation, purification, and structural and biological characterisation of three novel antimicrobial peptides from the skin secretions of the black spotted frog, Rana nigromaculata, ...
Li Peng - - 2013
The gas phase reactions of U(+) and U(2+) with H2O were investigated using an ab initio molecular dynamics method. All of the information along the minimum energy path were calculated with density functional theory (DFT) and coupled cluster methods. For U(+) with H2O, the molecular dynamics simulations yield a branching ...
Faraldo-García Ana - - 2013
Technological advances have led to the development of new measurement techniques that have improved the evaluation, diagnosis, and treatment of patients with vertigo, dizziness and balance disorders. The objective of this study was to propose population normality patterns, adjusted for age, for summary option (balance control summary, BCS) of Sway ...
Uchida Wataru - - 2013
We report a case of isolated pulmonary infectious endocarditis (IE) with Candida parapsilosis. A 66-year-old man presented with fever and cough. Echocardiography showed severe pulmonary regurgitation and vegetations on the pulmonary valves. Initially, antibiotics were prescribed against bacterial IE, and the vegetations disappeared; however, the pulmonary vegetations relapsed, and C. ...
Stensrud Mj - - 2013
Vesicular glutamate transporters (VGLUT1-3) carry glutamate into synaptic vesicles. VGLUT3 has been reported to be localized in non-glutamatergic neuronal populations in the brain. However, detailed subcellular localization of VGLUT3 has not been shown. In particular, the identity of synaptic vesicles expressing VGLUT3 remains to be revealed. Here we present novel ...
Li Jian-Long - - 2013
Abstract The complete mitochondrial (mt) genome of the chocolate hind Cephalopholis boenak was obtained in this study, which is the first complete mitogenome in the genus Cephalopholis. The circular mtDNA molecule was 16 771 bp in size and the overall nucleotide composition of the H-strand was 29.58% A, 27.36% T, 15.84% ...
Liu Anthony P Y - - 2013
We report on a male infant with de novo unbalanced t(5;15) translocation resulting in a 17.23 Mb deletion within 15q11.2-q14 and a 25.12 kb deletion in 5pter. The 15q11.2-q14 deletion encompassed the 15q11.2-q13 Prader-Willi syndrome (PWS) critical region and the recently described 15q13.3 microdeletion syndrome region while the 5pter deletion contained no ...
Zhang Li - - 2013
A mononuclear spin crossover compound Fe(AP-Mesal)2, which exhibits spin transitions near room temperature and light induced excited spin state trapping (LIESST) effects at low temperature, was synthesized and substructured in the form of micro- and nanoscaled particles. A thermal hysteresis loop was detected with particle size reduction to microscale and ...
Zhou Jian - - 2013
Abstract Background: Recent studies have identified postprandial glycemic excursions as risk factors for diabetes complications. This study aimed to compare the effects of nateglinide and acarbose treatments on postprandial glycemic excursions in Chinese subjects with type 2 diabetes. Subjects and Methods: This was a multicenter, open-label, randomized, active-controlled, parallel-group study. ...
Shinjyo Noriko - - 2013
Neural stem cells express cannabinoid CB1 and CB2 receptors and the enzymes for the biosynthesis and metabolism of endocannabinoids (eCBs). Here we have studied the role of neural stem cell-derived eCBs as autonomous regulatory factors during differentiation. First, we examined the effect of an indirect eCB precursor linoleic acid (LA), ...
Nakamura Teppei - - 2013
Abstract Milk-derived peptides, Val-Pro-Pro (VPP) and Ile-Pro-Pro (IPP), have angiotensin I-converting enzyme inhibitory activities and blood pressure-lowering effects. We examined the effects of these peptides on the development of atherosclerosis in apolipoprotein E-deficient [apoE(-/-)] mice. For 31 weeks, six-week-old male apoE(-/-) mice received a diet that included one of the ...
Bednářová Martina - - 2013
BACKGROUND: Considering the high content of protein, insects are a valuable alternative protein sources. However, no evaluation of purine content has so far been done. High content of purine derivates may lead to the exclusion of such food from the diet of people with specific diseases. The aim of the ...
Suraru Sabin-Lucian - - 2013
Nucleophilic substitution of tetrabromo-substituted naphthalene diimides (NDIs) with aniline was studied in detail to explore the regioselectivity as three different diamino-substituted regioisomeric products can be formed. We found that the regioselectivity of the nucleophilic disubstitution of 2,3,6,7-tetrabromonaphthalene diimide with aniline is dependent on reaction solvents and additives. In dichloromethane and ...
Johnson Eric F - - 2013
X-ray crystal structures are available for 29 eukaryotic microsomal, chloroplast or mitochondrial cytochrome P450s including two non-monooxygenase P450s. These structures provide a basis for understanding structure function relations that underlie their distinct catalytic activities. Moreover, structural plasticity has been characterized for individual P450s that aids in understanding substrate binding in ...
Moradiya Yogesh - - 2013
BACKGROUND AND PURPOSE: In-hospital stroke (IHS) differs from out-of-hospital stroke (OHS) in risk factors and outcomes. We compared IHS and OHS treated with thrombolysis from a large national cohort in a cross-sectional study to further clarify these differences. METHODS: The Nationwide Inpatient Sample for the years 2005-2010 was searched for ...
Ying Hou-Qun - - 2013
The deletion polymorphisms of the glutathione S-transferase M1 (GSTM1) and glutathione S-transferase T1 (GSTT1) gene were considered as candidates for genetic susceptibility factors of male infertility. Previous studies concerning the relationship between the null genotype of the two genes and male infertility have been reported in recent years. However, the ...
Böhmer M M - - 2013
General practitioners serve as important multipliers for seasonal influenza vaccination in risk groups such as elderly or chronically ill persons, for whom vaccination is recommended in Germany by the Standing Committee on Vaccination (STIKO). Moreover, physicians are a target group for influenza vaccination themselves.Data from 1 590 telephone interviews were ...
Lewinger Juan Pablo - - 2013
Exhaustive testing of all possible SNP pairs in a genome-wide association study (GWAS) generally yields low power to detect gene-gene (G × G) interactions because of small effect sizes and stringent requirements for multiple-testing correction. We introduce a new two-step procedure for testing G × G interactions in case-control GWAS ...
Jeon Jin Sue - - 2013
A 62-year-old woman with atrial fibrillation underwent burr hole trephination for a chronic subdural hematoma. Two days later the patient suddenly presented with motor dysphasia and slightly decreased motor power. Time of flight MR angiography revealed distal M1 occlusion without diffusion restriction. Stent-assisted mechanical thrombectomy was attempted but failed. Post-procedure ...
Vigna-Taglianti Federica - - 2013
BACKGROUND: Tranexamic acid (TXA) administered during arthroplasty intervention can prevent blood loss and blood transfusions. The purpose of the present study is to evaluate the benefit of TXA administration on blood transfusion rates in patients undergoing joint arthroplasty, and to perform cost-benefit analysis. METHODS: The study population included 100 patients ...
Cruzado J A - - 2013
Abstract Objectives: To study depression, anxiety, maladjustment and coping in caregivers of patients in vegetative state (VS) or minimally conscious state (MCS). Materials and methods: Fifty-three caregivers of 43 patients with VS or MCS were assessed using Beck Anxiety Inventory, Beck Depression Inventory, maladjustment scale and Brief Coping Orientation of ...
Morrison V A - - 2013
Background. After completion of the Shingles Prevention Study (SPS; VA Cooperative Studies Program #403), SPS placebo recipients were offered investigational zoster vaccine without charge. This provided an opportunity to determine the relative safety of zoster vaccine in older adults following documented herpes zoster (HZ).Methods. SPS placebo recipients who elected to receive ...
Mellou K - - 2013
SUMMARY In March 2012, there was an unusual increase of gastroenteritis cases in a district with 37 264 inhabitants in central Greece. It was estimated that more than 3600 people developed symptoms. A 1:1 case-control study showed that consumption of tap water was a risk factor for acquiring infection [odds ratio ...
Pluchino Stefano - - 2013
Advances in stem cell biology have raised great expectations that diseases and injuries of the central nervous system (CNS) may be ameliorated by the development of non-hematopoietic stem cell medicines. Yet, the application of adult stem cells as CNS therapeutics is challenging and the interpretation of some of the outcomes ...
Verdolini Abbott Katherine - - 2013
Voice disorders are the most common communication disorder across the life span, affecting more than five million school-aged children annually in the United States alone. Although such disorders are commonly associated with benign pathology, medically malicious conditions cannot be ruled out without proper medical examination by an otolaryngologist. Many children ...
Mateus André - - 2013
Intracellular unbound drug concentrations determine affinity to targets in the cell interior. However, due to difficulties in measuring them, they are often ignored in pharmacology. Here we present a simple experimental technique for the determination of unbound intracellular drug concentrations in cultured cells that is based on parallel measurements of ...
Joshi Pratixa P - - 2013
Anisotropic gold nanorods provide a convenient combination of properties, such as tunability of plasmon resonances and strong extinction cross-sections in the near-infrared to red spectral region. These properties have created significant interest in the development of antibody conjugation methods for synthesis of targeted nanorods for a number of biomedical applications, ...
Morgan Stuart A - - 2013
The prevalence of insulin resistance and type 2 diabetes mellitus are rising dramatically and as a consequence there is an urgent need to understand the pathogenesis underpinning these conditions to develop new and more efficacious treatments.We have tested the hypothesis that glucocorticoid-mediated changes in insulin sensitivity may be associated with ...
Zhang Caili - - 2013
A new kind of functional graphene oxide with fine stability in water was fabricated by mixing graphene oxide (GO) and brilliant blue (BB) with certain weight ratio. The adsorption performance of this mixture of BB and GO (BBGO) to polycyclic aromatic hydrocarbons (anthracenemethanol (AC) and fluoranthene (FL)) was investigated, and ...
Montebugnoli Lucio - - 2013
BACKGROUND: Histological and clinical criteria are generally used to differentiate second primary tumors (SPTs) from local recurrences. The purpose of the present study was to apply mitochondrial DNA (mtDNA) D-loop analysis to differentiate SPTs from local recurrences and to validate the clinical classification. METHODS: The study population consisted of 20 ...
Day Fiona L - - 2013
PURPOSE: PIK3CA and PTEN mutations are prevalent in colorectal cancer (CRC), and potential markers of response to MEK inhibitors and anti-EGFR antibody therapy. Relationships between PI3K pathway mutation, clinicopathological characteristics, molecular features and prognosis remain controversial. EXPERIMENTAL DESIGN: 1,093 stage I-IV CRCs were screened for PIK3CA (exons 9, 20), KRAS ...
Rey Michaël - - 2013
We report global calculations of rovibrational spectra and dipole transition intensities of methane using our recent ab initio dipole moment and potential surfaces [Nikitin et al., Chem. Phys. Lett., 2011, 501, 179; 2013, 565, 5]. For the full symmetry account, a recently published variational tensor formalism in normal modes [Rey ...
Ulewicz-Magulska Beata - - 2013
Abstract The aim of this study was to evaluate the level of selenium (Se) in common raw plant materials (herbs, leaves, flowers, fruits, and roots) obtained from medicinal plants cultivated in Poland. Furthermore, the relationship between the morphological part of a plant and its species was examined, and the concentration ...
Belofsky Gil - - 2013
New potential treatments for disseminated fungal infections are needed, especially for infections caused by the commonly drug-resistant pathogens Candida albicans and C. glabrata. These pathogens cause systemic candidiasis, a significant cause of mortality in immune-compromised patients. ABC transporters of the pleiotropic drug resistance subfamily, such as Cdr1p of C. albicans, ...
Kent Michael L - - 2013
BACKGROUND:Blockade of the saphenous nerve is often used for surgeries below the knee. Depending on the approach, success rates vary widely ranging from 33% to 88%. In this prospective volunteer study, we compared 2 ultrasound-guided techniques, the modified vastus medialis and perifemoral saphenous nerve block with a below the knee ...
Niikura Kenichi - - 2013
This paper demonstrates how the shape and size of gold nanoparticles (AuNPs) affects immunological responses in vivo and in vitro for the production of antibodies for West Nile virus (WNV). We prepared spherical (20 and 40 nm in diameter), rod (40 x 10 nm), and cubic (40 x 40 x ...
Hopley Philip J - - 2013
Following the discovery of the "Taung Child" (Australopithecus africanus) in 1924 in the Buxton-Norlim Limeworks near Taung, the fossil-bearing deposits associated with the Dart and Hrdlička pinnacles have been interpreted as the mined remnants of cave sediments that formed within the Plio-Pleistocene Thabaseek Tufa: either as a younger cave-fill or ...
García Vicente Ana María - - 2013
PURPOSE: To determine whether the metabolic features of breast tumours differ among molecular subtypes. METHODS: This prospective study included 168 women diagnosed with locally advanced breast cancer. PET/CT was requested in the initial staging before neoadjuvant treatment (multicentre study, FISCAM grant). All patients underwent an (18)F-FDG PET/CT scan with a ...
Behrens Maik - - 2013
Mutational polymorphism in the TAS2R38 bitter taste receptor is a key determinant of threshold taste detection of isolated compounds, such as phenylthiocarbamide (PTC) and propylthiouracil (PROP), as well as complex orosensation-mediated traits such as diet choice and smoking habits. These relationships are accounted for, in part, by 2 common alleles ...
Padron Eric - - 2013
Granulocyte-macrophage colony stimulating factor (GM-CSF) hypersensitivity is a hallmark of Juvenile Myelomonocytic Leukemia (JMML) but has not been systematically shown in the related human disease Chronic Myelomonocytic Leukemia (CMML). We find that primary CMML samples demonstrate GM-CSF-dependent hypersensitivity by hematopoietic colony formation assays and phospho-STAT5 (pSTAT5) flow cytometry compared to ...
Eren Erdem - - 2013
Endoscopic sinus surgery is a widely used technique in otolaryngologic practice. To avoid complications, the locations of important anatomical structures, such as the anterior ethmoid artery (AEA), should be determined preoperatively. We want to evaluate the effect of ethmoid cavity pneumatization on the location of the AEA and to determine ...
Shao Xiayan - - 2013
Abstract Concanavalin A (ConA)-conjugated poly(ethylene glycol)-poly(lactic acid) nanoparticles (ConA-NPs) were prepared for targeted drug delivery to the cervical lymph nodes after intranasal administration. ConA, a lectin specifically binding to α-mannose and α-glucose, was covalently conjugated on NPs without loss of its carbohydrates binding bioactivity. In vitro cellular uptake experiment demonstrated ...
Chang Chia-Hao - - 2013
Abstract The complete mitochondrial genome of the big-eye thresher shark was sequenced using a polymerase chain reaction (PCR)-based method. The total length of mitochondrial DNA is 16,719 bp and includes 13 protein-coding genes, 2 ribosomal RNA, 22 transfer RNA genes, 1 replication origin region and 1 control region. The mitochondrial gene ...
Ren Wei-Min - - 2013
The chiral SalenCo(III)OAc-catalyzed hydrolytic kinetic resolution (HKR) of racemic terminal epoxides to afford both enantioenriched epoxides and diols presents one of the most important achievements in the asymmetric synthesis chemistry. Previous studies mainly focused on the development of highly efficient catalysts, while rare report concerned the mechanistic understanding on metal ...
Kushner Brian H - - 2013
BACKGROUND: Posterior reversible encephalopathy syndrome (PRES) comprises clinical and radiologic findings with rapid onset and potentially dire consequences. Patients experience hypertension, seizures, headache, visual disturbance, and/or altered mentation. Magnetic resonance imaging reveals edematous changes in the brain (especially in the parietal and occipital lobes). In this report, the authors describe ...
Thomas Charles - - 2013
Abstract Purpose: To ask whether dose-rate influences low-dose hyper-radiosensitivity and induced radioresistance (HRS/IRR) response in rat colon carcinoma PRO and REG cells. Methods: Clonogenic survival was applied to tumourigenic PRO and non-tumourigenic REG cells irradiated with (60)Co γ-rays at 0.0025-500 mGy.min(-1). Both clonogenic survival and non-homologous end-joining (NHEJ) pathway involved ...
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