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Results 401 - 450 of 2959
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Cao Xiong - - 2013
Astrocytes are key components of the niche for neural stem cells (NSCs) in the adult hippocampus and play a vital role in regulating NSC proliferation and differentiation. However, the exact molecular mechanisms by which astrocytes modulate NSC proliferation have not been identified. Here, we identified adenosine 5'-triphosphate (ATP) as a ...
Kjerholt Mette - - 2013
BACKGROUND: Continuity is crucial when caring for older chronically ill patients. Research has shown that the integration of patients' own perspectives on their situation is of utmost importance for continuity and quality of care. Studies have, however, demonstrated a number of problems with health professionals' communication concerning older patients, leading ...
Min Y - - 2013
BACKGROUND: The present study aimed to assess the dietary fat intake and blood fatty acid status of healthy Norwegian men and women living in Bergen whose habitual diet is known to be high in long-chain omega-3 fat. METHODS: Healthy men (n = 41) and women (n = 40) aged 20-50 years who were regular blood ...
Kobayashi Masanori - - 2013
In healthy male dogs, peripheral plasma testosterone (T), prostaglandin E2 (PGE2), and seminal plasma PGE2 levels were measured before, during, and after ejaculation and semen quality was examined after oral administration of PGE2. Plasma T and PGE2 levels did not change during these periods, but seminal plasma PGE2 level in ...
Zhou Zhen - - 2013
The nona-Cu(II)-containing tungstoarsenate(iii) [H4{Cu(II)9As(III)6O15(H2O)6}(α-As(III)W9O33)2](8-) () has been synthesized and characterized. Polyanion comprises a unique, cylindrical {Cu(II)9As(III)6O15(H2O)6}(6+) cluster, which forms a large central cavity and is capped on either end by an [α-As(III)W9O33](9-) capping group. It exhibits remarkable activity against K562 leukaemia cells, as well as induces HepG2 cell apoptosis and ...
Bergström Ann-Kristin - - 2013
The aim of this study was to predict the combined effects of enhanced nitrogen (N) deposition and warming on phytoplankton development in high latitude and mountain lakes. Consequently, we assessed, in a series of enclosure experiments, how lake water nutrient stoichiometry and phytoplankton nutrient limitation varied over the growing season ...
Trimboli Pierpaolo - - 2013
OBJECTIVE: Only few studies analyzed the capability of cytology in detecting medullary thyroid cancer (MTC), and they reported a low accuracy of this diagnostic technique. Recently, calcitonin (CT) measurement in aspiration needle washout (FNA-CT) of thyroid and neck lesions has been reported as sensitive tool for MTC. The aim of ...
Calabrò Rocco Salvatore - - 2013
ABSTRACT The aim of the study was to evaluate the prevalence and the etiology of sexual dysfunctions in a group of epileptic outpatients. Sixty Italian men (30 patients and 30 controls), living in Sicily, were enrolled in the study. Our diagnostic investigation included physical and neurological examination, EEG, MRI, and ...
Liu Xue - - 2013
The volatile components of Nigella sativa seeds were isolated using microwave-assisted extraction (MAE) and identified using gas chromatography. Further investigations were carried out to demonstrate the effects of whole extracts on canine (dog) and murine (rat) cytochrome P450 1A (CYP1A). The optimal extraction conditions of MAE were as follows: 25 mL ...
Kargi Atil Y - - 2013
The availability of synthetic recombinant human growth hormone (GH) in potentially unlimited quantities since the 1980s has improved understanding of the many nonstatural effects of GH on metabolism, body composition, physical and psychological function, as well as the consequences of GH deficiency in adult life. Adult GH deficiency is now ...
Howard Lauren E - - 2013
Holocephalans (chimaeras) are a group of marine fishes comprising three families: the Callorhinchidae (callorhinchid fishes), the Rhinochimaeridae (rhinochimaerid fishes) and the Chimaeridae (chimaerid fishes). We have used X-ray microcomputed tomography and magnetic resonance imaging to characterise in detail the nasal anatomy of three species of chimaerid fishes: Chimaera monstrosa, C. ...
Li Yibing - - 2013
Cross-linked rather than non-covalently bonded graphitic carbon nitride (g-C3 N4 )/reduced graphene oxide (rGO) nanocomposites with tunable band structures have been successfully fabricated by thermal treatment of a mixture of cyanamide and graphene oxide with different weight ratios. The experimental results indicate that compared to pure g-C3 N4 , the ...
Laurberg Peter - - 2013
Thyroid hormones are important regulators of foetal development, and in recent years there has been much focus on the screening and treatment of pregnant women for even small aberrations in thyroid function tests. We searched PubMed for publications on thyroid function and pregnancy outcomes including child cognition, and included references ...
Abdel-Rehim Abbi - - 2013
This study presents a new method for collecting and handling saliva samples using an automated analytical microsyringe and microextraction by packed syringe (MEPS). The screening and determination of lidocaine in human saliva samples utilizing MEPS and liquid chromatography-tandem mass spectrometry (LC-MS/MS) were carried out. An exact volume of saliva could ...
Bui Ds - - 2013
BACKGROUND AND OBJECTIVE: The impact of ambient wood smoke and traffic-related air pollution on adult asthma has not been well studied. This paper aims to investigate associations between exposure to ambient wood smoke, traffic-related air pollution and current asthma / asthma severity in middle-age, and whether any associations are modified ...
Teive Helio A - - 2013
Messina et al.(1) presented a 39-year-old woman with Urbach-Wiethe disease or lipoid proteinosis (LP) who developed right hemiparesis due to a left lenticular nucleus hemorrhage. The authors suggested that LP is associated with diffuse small-vessel disease. LP is a rare autosomal recessive disease due to mutations in the extracellular matrix ...
Szczurek Ewa - - 2013
Synthetic lethal interactions in cancer hold the potential for successful combined therapies, which would avoid the difficulties of single molecule-targeted treatment. Identification of interactions that are specific for human tumors is an open problem in cancer research. This work aims at deciphering synthetic sick or lethal interactions directly from somatic ...
Fung James - - 2013
OBJECTIVES:The long-term outcomes of oral antiviral therapy without hepatitis B immune globulin (HBIG) in prevention of reinfection with hepatitis B after liver transplantation are not known. We aimed to determine the long-term outcomes from a large population of chronic hepatitis B (CHB) liver transplant recipients using oral antiviral therapy alone.METHODS:A ...
Beasley Spencer W - - 2013
Critical review of the close marking system used in the Fellowship Examination revealed that minor modifications to the way in which it was employed could significantly improve the quality (reliability and validity) of the examination. In addition, it could provide better information for the specialty courts to use during their ...
Mo Yufei - - 2013
This paper describes an application for atomic force microscopy to the fabrication of nanotextures with various features on GaAs surface by local oxidation nanolithography (LON). By controlling the geometrical shapes and surface coverage of the nanotexture, the surface adhesion can be adjusted to a low adhesive surface. The influence of ...
Palmans H - - 2013
The conversion of absorbed dose-to-graphite in a graphite phantom to absorbed dose-to-water in a water phantom is performed by water to graphite stopping power ratios. If, however, the charged particle fluence is not equal at equivalent depths in graphite and water, a fluence correction factor, kfl, is required as well. ...
Fras F - - 2013
The initialization of a resident hole spin by the absorption of a circularly polarized light at resonance involves the formation of an excited state called a trion state. For a pure heavy hole, this optical initialization is mediated by the hyperfine electron-nuclear coupling in the trion state. We show here ...
Arnò Raffaella - - 2013
Objective. To evaluate number, type, and complexity of arrhythmias in diabetics compared with controls and, among diabetics, comparing good glycaemic control (GGC) and poor glycaemic control (PGC) patients. Methods. We compared Ambulatory Electrocardiogram recordings of 92 diabetics and 100 controls. The glycaemic profile of 50 diabetics, taken the same day ...
Markiewicz Marta - - 2013
Increased use and production of ionic liquids (ILs) may result in emissions into the environment. Particularly vulnerable are industrial areas and landfills where ILs are utilized and ultimately disposed of. This study investigates how IL contamination can affect soil properties and the sorption of pre-existing contaminants. The commonly used IL ...
Vandersluis Avi D - - 2013
BACKGROUND: The relationships between diet, exercise, and prostate cancer (PCa) remain unclear. We have previously reported that a "Western" diet promotes PCa tumor growth in vivo. Presently, we report the effects of sustained aerobic exercise on PCa progression in animals fed a high-fat diet versus a standard diet. METHODS: Athymic ...
Panzavolta Silvia - - 2013
Bone cell response to 3D bioinspired scaffolds was tested on osteoblast culture supernatants and by means of quantitative polymerase chain reaction (qPCR). Foaming and freeze-drying method was optimized in order to obtain three-dimensional interconnected porous scaffolds of gelatin at different contents of nanocrystalline hydroxyapatite (HA). Addition of a non toxic ...
Veloso R R RR - - 2013
Considering the increased incidence of obesity and metabolic diseases in caged psittacines, the effect of fibre and food processing was evaluated in the Blue-and-gold macaw. Four food formulations (0%, 7%, 14% and 21% of sugarcane fibre) processed by pelleting or extrusion were studied, resulting in eight diets. To study digestibility, ...
Ihrai Tarik - - 2013
Abstract Autologous fat transfer (AFT) enhances the cosmetic results of breast reconstruction and corrects breast conserving operation sequelae. The question of its oncological safety remains, as in-vitro experiences have shown that adipocytes can stimulate cancer cell proliferation. This study analysed the records of patients who had AFT after breast cancer ...
Rodriguez Hugo - - 2013
Animals living in nontropical climates modify their physiology and behavior to adapt to seasonal environmental changes. Part of this adaptation involves the release of catecholamine from sympathetic nerve endings and the adrenal medulla, which play a major role in regulating energy balance. The aim of this work was to investigate ...
Qiu Y - - 2013
BACKGROUND: Infantile haemangiomas (IHs) are the most common vascular tumours of infancy. Topical therapies are a possible treatment for superficial IHs. AIM: To determine the efficacy and safety of topical therapy in the treatment of superficial proliferating IHs. METHODS: The medical records of all the patients with proliferating superficial IHs ...
Marx Harald - - 2013
Protein sequence databases are indispensable tools for life science research including mass spectrometry (MS)-based proteomics. In current database construction processes, sequence similarity clustering is used to reduce redundancies in the source data. Albeit powerful, it ignores the peptide centric nature of proteomic data and the fact that MS is able ...
Marek-Trzonkowska Natalia - - 2013
Regulatory T cells (Tregs) are responsible for the maintenance of peripheral tolerance. Animal studies have shown that administration of Tregs can prevent type 1 diabetes (DM1). Several clinical trials attempted to induce Tregs with various agents, and thus provide long-term tolerance of β cells in DM1. Nevertheless, most of these ...
Blanco Giovanna Del Vecchio - - 2013
BACKGROUND: First-degree relatives (FDR) of patients with colorectal cancer (CRC) have an increased CRC risk. Few studies have addressed if adenoma and advanced adenoma risk is increased among individuals with family history of CRC aged 40-49 years. AIM: To define prevalence and location of adenoma, advanced adenoma and CRC according ...
White Christopher J - - 2013
From the earliest experiences with carotid artery stenting (CAS) presumptive high risk features have included thrombus-containing lesions, heavily calcified lesions, very tortuous vessels, and near occlusions. In addition patients have been routinely excluded from CAS trials if they have contra-indications to dual antiplatelet therapy (aspirin and thienopyridines), a history of ...
Sadava Emmanuel E - - 2013
In recent years, major advances have been accomplished in abdominal wall reconstruction. Introduction of newer prostheses have improved outcomes, but elimination of mesh-related morbidity is still an elusive issue. It is believed that host foreign body reaction to prosthesis plays an important role in the biology of these complications, so ...
Gu Jiamin - - 2013
A rapid and convenient method was established to preparatively isolate the three ellagic acid types of compounds, which were the main polyphenols in Euphorbia pekinensis, by flexibly applying solvent extraction combined with counter-current chromatography. The total extract (extracted using 95% ethanol) of Euphorbia pekinensis was pretreated by two simple steps ...
Imaizumi Atsushi - - 2013
Abstract Composite grafting, grafting without microvascular anastomoses, has been widely performed for distal fingertip amputation in children with variable results, whereas successful replantation of these amputations using microsurgical technique has been reported. However, most of these reports included a wide age-range and a mix of different amputation levels. This study ...
Gil Mariona - - 2013
The influence of two treatments for reducing grape yield - cluster thinning and berry thinning - on red wine composition and quality were studied in a Vitis vinifera cv Syrah vineyard in AOC Penedès (Spain). Cluster thinning reduced grape yield per vine by around 40% whereas berry thinning only reduced ...
Zhang Qian - - 2013
A facile and efficient protocol for palladium-catalyzed ortho-acylation of 2-aryl pyridines was developed. Note that this acylation utilized arylmethyl amines as new, cheap and readily available acylation reagents and exhibited high regioselectivity for 2-aryl pyridines bearing a meta-substituent in the aryl ring moiety.
Graham Deirdre - - 2013
A 25-year-old man presented with subacute spastic paraparesis. He reported 2 previous episodes of spastic paraparesis with partial recovery. Recurrent oral and genital ulceration, pustular skin eruptions, and fever coexisted. Profound motor weakness, a sensory level at T10, oral ulceration, and a pustular eruption on the anterior abdominal wall were ...
Meyer Armin H - - 2013
Atrazine (Atz) and its metabolite desethylatrazine (DEA) frequently occur in the environment. Conclusive interpretation of their transformation is often difficult. This study explored evidence from 13C/12C and 15N/14N isotope trends in parent and daughter compound when Atz was dealkylated by (i) permanganate and (ii) the bacterium Rhodococcus sp. NI86/21. In ...
Bindal Natish - - 2013
Background: Workplace based assessments (WBAs) have been part of UK training for the last 3 years. Carrying out procedures efficiently and safely is of paramount importance in anaesthesia. Aims: To explore opinions and experiences of Direct Observation of Procedural Skills (DOPS) assessments in a regional anaesthetic training programme. Methods: 19 ...
Guo Y - - 2013
Autonomic dysfunction is common in patients with cancer and may have considerable negative effects on quality of life and mortality. This study retrospectively compared heart rate variability measured by the standard deviation of normal-to-normal intervals (SDNN) to Ewing test score, a composite score from a battery of five defined autonomic ...
Moosazadeh Mahmood - - 2013
INTRODUCTION: Different studies show that a considerable number of pregnancies are unwanted and can have side effects on mothers'' children's and finally society's health. Accordingly, this meta-analysis study has been carried out to estimate a relatively accurate level of unwanted pregnancies in Iran. METHODS: Present studies and published documents were ...
Durán Jorge - - 2013
Despite growing recognition of the role that cities have in global biogeochemical cycles, urban systems are among the least understood of all ecosystems. Urban grasslands are expanding rapidly along with urbanization, which is expected to increase at unprecedented rates in upcoming decades. The large and increasing area of urban grasslands ...
McGowan C A - - 2013
BACKGROUND: To date, there are no food frequency questionnaires that have been validated to assess nutrient intakes in pregnant women in Ireland. The present study aimed to assess the relative validity of a self-administered food frequency questionnaire during pregnancy. METHODS: The food frequency questionnaire was administered once during pregnancy between ...
Takumida Masaya - - 2013
Abstract Conclusion: We found that aquaporins (AQPs) in the fluid transporting cells, such as vestibular dark cells and endolymphatic sac epithelial cells, seem to be of importance in fluid transport in the inner ear, while those in the sensory and ganglion cells may play a functional role in sensory cell ...
Masini Emanuela - - 2013
Introduction: Glaucoma is one of the major causes of blindness, affecting together with age-related macular degeneration > 70 million people worldwide. One of the therapeutic options for its management is based on the inhibition of the metalloenyme carbonic anhydrase (CA, EC 4.2.1.1). CA inhibitors (CAIs) diminish intraocular pressure (IOP) by ...
Du Qiaoling - - 2013
AIM: To investigate TNF-α expression and its relationship with serum bile acids in placental trophoblasts from patients with intrahepatic cholestasis of pregnancy (ICP). METHODS: Human placenta, including normal pregnancies (N=10) and patients with ICP (N=10), were collected at term and subject to TNF-α measurements. Bile acids-induced TNF-α expression and cell ...
Kloosterhof Nanne K - - 2013
Recent studies have indicated a prognostic role for genome-wide methylation in gliomas: Tumors that show an overall increase in DNA methylation at CpG sites (CIMP+; CpG island methylator phenotype) have a more favorable prognosis than CIMP- gliomas. Here, we have determined whether methylation profiling can identify more and clinically relevant ...
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