Search Results
Results 301 - 350 of 2977
< 2 3 4 5 6 7 8 9 10 11 12 >
Adams Chris - - 2013
Abstract Estrogen has been implicated in controlling the pathogenesis and symptoms of Parkinson's disease (PD) in women. Here, we report a 53-year-old male with PD who underwent estrogen therapy with estradiol (E2). Within a month, he exhibited increased dyskinesias. His medication was reduced by 35% from a levodopa equivalent dose ...
Ly A R - - 2013
BACKGROUND: There is a relative lack of measures tailored to the study of fathers of children with developmental challenges (DCs). The goal of the current study was to create and validate a brief measure designed to capture the perceptions and experiences of these fathers. The Fathers of Children with Developmental ...
Valachis Antonis - - 2013
Although dual HER2 blockade shows promising results in patients with HER2-positive breast cancer it is unclear whether this treatment strategy increases the risk for cardiac adverse events. We conducted a meta-analysis of randomized trials to investigate the risk of cardiac adverse events when a combination of anti-HER2 therapies compared to ...
Marigo Juliana - - 2013
The cetacean flipper consists of a soft tissue that encases most of the forelimb containing humerus, radius, ulna, carpals, metacarpals, and phalanges. Several studies have documented the typical cetacean's flipper anatomy, but only a few described digital anomalies and the most common are fusions and supernumerary such as polydactily and ...
Tanaka Yusuke - - 2013
  It is well known that large differences exist in the bioavailability of orally administered drugs between species. Dissolution is the first step in the oral absorption of solid drugs. In this study, we measured the in vivo luminal concentrations of griseofulvin (GF) and albendazole (AZ), Biopharmaceutics Classification System (BCS) class ...
McGowan C A - - 2013
BACKGROUND: To date, there are no food frequency questionnaires that have been validated to assess nutrient intakes in pregnant women in Ireland. The present study aimed to assess the relative validity of a self-administered food frequency questionnaire during pregnancy. METHODS: The food frequency questionnaire was administered once during pregnancy between ...
Takumida Masaya - - 2013
Abstract Conclusion: We found that aquaporins (AQPs) in the fluid transporting cells, such as vestibular dark cells and endolymphatic sac epithelial cells, seem to be of importance in fluid transport in the inner ear, while those in the sensory and ganglion cells may play a functional role in sensory cell ...
Masini Emanuela - - 2013
Introduction: Glaucoma is one of the major causes of blindness, affecting together with age-related macular degeneration > 70 million people worldwide. One of the therapeutic options for its management is based on the inhibition of the metalloenyme carbonic anhydrase (CA, EC 4.2.1.1). CA inhibitors (CAIs) diminish intraocular pressure (IOP) by ...
Du Qiaoling - - 2013
AIM: To investigate TNF-α expression and its relationship with serum bile acids in placental trophoblasts from patients with intrahepatic cholestasis of pregnancy (ICP). METHODS: Human placenta, including normal pregnancies (N=10) and patients with ICP (N=10), were collected at term and subject to TNF-α measurements. Bile acids-induced TNF-α expression and cell ...
Kloosterhof Nanne K - - 2013
Recent studies have indicated a prognostic role for genome-wide methylation in gliomas: Tumors that show an overall increase in DNA methylation at CpG sites (CIMP+; CpG island methylator phenotype) have a more favorable prognosis than CIMP- gliomas. Here, we have determined whether methylation profiling can identify more and clinically relevant ...
Weerts Aurelie P - - 2013
Abstract Conclusion: This study showed that GABAB agonist baclofen (10 mg) affects the semicircular canals (SCCs), both centrally and peripherally, but does not influence the otolithic function. Objectives: The aim of the study was to identify the effects of baclofen on the complete vestibular system, i.e. semicircular canals, saccules and ...
Hulka L M - - 2013
Long-lasting neuroadaptations in the glutamatergic corticostriatal circuitry have been suggested to be responsible for the persisting nature of drug addiction. In particular, animal models have linked the metabotropic glutamate receptor 5 (mGluR5) to drug-seeking behavior and extinction learning. Accordingly, blocking mGluR5s attenuated self-administration of cocaine and other addictive drugs in ...
Xu Can - - 2013
Herein, a pH stimuli-responsive vehicle for intracellular drug delivery using CeO2 capped mesoporous silica nanoparticles (MSN) is reported. β-Cyclodextrin-modified CeO2 nanoparticles could cap onto ferrocene-functionalized mesoporous silica through host-guest interactions. After internalization into A549 cells by a lysosomal pathway, the ferrocenyl moieties are oxidized to ferrocenium ions by CeO2 lids, ...
Lloyd Stacy M - - 2013
Lung cancer is the leading cause of all cancer-related deaths in the US. The need to develop more accurate cancer risk assessment tools is imperative to improve the ability to identify individuals at greatest risk of developing disease. The Cytokinesis-Blocked Micronucleus Cytome Assay (CBMNcyt) presents a sensitive and specific method ...
Mikami Koichiro - - 2013
An organocatalyzed ring-opening polymerization methodology was developed for the preparation of polycarbonates derived from glucose as a natural product starting material. The cyclic 4,6-carbonate monomer of glucose having the 1, 2, and 3 positions methyl-protected was prepared in three steps from a commercially available glucose derivative, and the structure was ...
Ichimiya Makoto - - 2013
Abstract Groin lymph node dissection (GLND) remains an effective treatment for malignant neoplasms of the skin arising on the lower extremities and perineum. However, complications such as seroma, flap necrosis, and infections have been encountered. It is thought that a conventional operation using a long inguinal incision can result in ...
Koch Sonja - - 2013
This study is part of the larger Christina Barz Study, and it compared consecutively admitted patients with purging disorder (PurD; N = 225) with consecutively admitted patients with anorexia nervosa binge eating/purging subtype (AN-bp; N = 503) and bulimia nervosa purging subtype (BN-p; N = 756). Participants answered self-rating questionnaires on admission, at the end of ...
Tonstad S - - 2013
BACKGROUND: High-fibre and low-carbohydrate diets may enhance satiety and promote weight loss. We compared a diet rich in beans aiming to increase dietary fibre and promote weight loss with a low-carbohydrate diet in a randomised controlled trial to assess effect and tolerability of the high-fibre bean-rich diet. METHODS AND RESULTS: ...
Devkota Bhuminand - - 2013
Because the role of bone turnover during early to peak lactation in dairy cows is unclear, plasma levels of osteoclast- or collagen-specific bone resorption and osteoblast-specific bone formation markers from postpartum week 3 (W+3) to W+7 were compared with prepartum W-3 levels in multiparous (n=15) and primiparous (n=13) Holstein cows. ...
Spear Paul - - 2013
Tumor heterogeneity presents a substantial barrier to increasing clinical responses mediated by targeted therapies. Broadening the immune response elicited by treatments that target a single antigen is necessary for the elimination of tumor variants that fail to express the targeted antigen. In this study, it is shown that adoptive transfer ...
Smpokos E A - - 2013
BACKGROUND: There is lack of data in Greece on the trends in energy and nutrient intake. The present study aimed to examine differences in these parameters among first-grade children of Crete, Greece, between 1992/93 and 2006/07. METHODS: Children (aged 5.7-7.6 years) from two-representative cross-sectional samples participated during 1992/93 (n = 245) and 2006/07 ...
Rommelfanger Karen S - - 2013
Psychogenic movement disorders (PMDs) mimic known movement disorders but are not attributed to an underlying neurological pathology and are generally thought to have a psychological origin. Owing to the lack of a clear pathology, patients often experience multiple referrals, frequent office visits, and numerous-often fruitless-technically sophisticated tests and interventions. No ...
Sinsabaugh Robert L - - 2013
Carbon use efficiency (CUE) is a fundamental parameter for ecological models based on the physiology of microorganisms. CUE determines energy and material flows to higher trophic levels, conversion of plant-produced carbon into microbial products and rates of ecosystem carbon storage. Thermodynamic calculations support a maximum CUE value of ~ 0.60 (CUE ...
Van Dam D - - 2013
Neuropeptides are found throughout the entire nervous system where they can act as neurotransmitter, neuromodulator or neurohormone. In those functions, they play important roles in the regulation of cognition and behavior. In brain disorders like Alzheimer's disease (AD), where abnormal cognition and behavior are observed, the study of neuropeptides is ...
Lee Junghan J Department of Chemistry, Florida International University, Miami, FL 33199, - - 2013
Understanding the cellular entry pathways of synthetic biomaterials is highly important to improve overall labeling and delivery efficiency. Herein, cellular entry mechanisms of conjugated polymer nanoparticles (CPNs) are presented. CPNs are intrinsic fluorescent materials used for various biological applications. While CPNs cause no toxicity, decreased CPN uptake is observed from ...
Park Il-Jung - - 2013
Abstract The aetiology of anterior interosseous nerve (AIN) syndrome and an optimal treatment strategy remain controversial. Eleven patients with spontaneous AIN syndrome, who were treated by surgical exploration, were reviewed at a mean of 32.5 months after the operation. Eight men and three women were included in the study. None ...
Molina-Estevez F Javier - - 2013
Although there is an increasing interest in defining the role of DNA damage response mechanisms in cell reprogramming, the relevance of proteins participating in Non-Homologous End Joining (NHEJ), a major mechanism of DNA double strand breaks repair, in this process remains to be investigated. Herein, we present data related to ...
Li Yibing - - 2013
Cross-linked rather than non-covalently bonded graphitic carbon nitride (g-C3 N4 )/reduced graphene oxide (rGO) nanocomposites with tunable band structures have been successfully fabricated by thermal treatment of a mixture of cyanamide and graphene oxide with different weight ratios. The experimental results indicate that compared to pure g-C3 N4 , the ...
Laurberg Peter - - 2013
Thyroid hormones are important regulators of foetal development, and in recent years there has been much focus on the screening and treatment of pregnant women for even small aberrations in thyroid function tests. We searched PubMed for publications on thyroid function and pregnancy outcomes including child cognition, and included references ...
Mieog Jos C - - 2013
BACKGROUND: A crucial step in the evaluation of newly produced transgenic plants is the selection of homozygous plants. Here we describe an efficient and highly flexible real-time PCR-based method for the development of homozygous lines in plant models with complex (multiple) genomes and/or relatively long generation times (>3 months) using ...
Abdel-Rehim Abbi - - 2013
This study presents a new method for collecting and handling saliva samples using an automated analytical microsyringe and microextraction by packed syringe (MEPS). The screening and determination of lidocaine in human saliva samples utilizing MEPS and liquid chromatography-tandem mass spectrometry (LC-MS/MS) were carried out. An exact volume of saliva could ...
Ohki Takamasa - - 2013
OBJECTIVES:The combination of computed tomography with hepatic arteriography and arterial portography (CTHA/CTAP) can detect additional hepatocellular carcinoma (HCC) nodules undetected by conventional dynamic CT.METHODS:In this single-center, randomized, open-label, controlled trial, we randomly assigned 280 patients who were diagnosed as having HCC by conventional dynamic CT, and eligible for radiofrequency ablation ...
Bui Ds - - 2013
BACKGROUND AND OBJECTIVE: The impact of ambient wood smoke and traffic-related air pollution on adult asthma has not been well studied. This paper aims to investigate associations between exposure to ambient wood smoke, traffic-related air pollution and current asthma / asthma severity in middle-age, and whether any associations are modified ...
Jung Andrew K - - 2013
Developmental venous anomalies (DVA) are normally diminutive and incidental.(1,2) In this 33-year-old patient with epilepsy, the DVA is holohemispheric. Her epilepsy probably originates from the left side based on semiology; the EEG displayed left-sided slowing. Axial T1-weighted sequences show skull atrophy, ventricular widening, and satellite cavernous malformations with accumulation of ...
Gu Jinyu - - 2013
AIM: The aim of the study was to evaluate factors affecting postoperative outcomes after laparoscopic total abdominal colectomy (TAC) with end ileostomy (EI) for ulcerative colitis (UC). METHOD: Patients undergoing laparoscopic TAC/EI for severe UC/indeterminate colitis during 1998-2010 in our institution were retrospectively identified from a prospectively established database. Demographics, ...
Misra Rajneesh - - 2013
This article reports the design, and synthesis of D-pi1-A-pi2-D unsymmetrical, and D-pi1-A-pi2-A-pi1-D symmetrical type of ferrocenyl substituted benzothiadiazoles by the Pd-catalyzed Sonogashira, and Stille coupling reactions. The photophysical, and electrochemical behavior of the ferrocenyl substituted benzothiadiazoles show strong donor-acceptor interaction. The increase in the number of acceptor benzothiadiazole unit, results ...
Jippes Mariëlle - - 2013
Background: Earlier studies suggested national culture to be a potential barrier to curriculum reform in medical schools. In particular, Hofstede's cultural dimension 'uncertainty avoidance' had a significant negative relationship with the implementation rate of integrated curricula. Aims: However, some schools succeeded to adopt curriculum changes despite their country's strong uncertainty ...
Abeysinghe Samangi S Department of Chemistry, University of Iowa, W374 Chemistry Building, Iowa City, Iowa 52242, United - - 2013
Keggin-type molecular clusters formed from the partial hydrolysis of aluminum in aqueous solutions have the capacity to adsorb a variety of inorganic and organic contaminants. The adsorptive capability of Keggin-type polyaluminum species, such as Al13 and Al30, lead to their wide usage as precursors for heterogeneous catalysts and clarifying agents ...
Park Jiyoung J Department of Internal Medicine, The University of Texas Southwestern Medical Center, Dallas, TX, - - 2013
Endotrophin is a cleavage product of collagenVIα3 (COL6A3). Here, we explore the relationship between thiazolidinediones (TZDs), endotrophin and cisplatin resistance in the context of a mammary tumour model. COL6A3 levels are increased in response to cisplatin exposure in tumours. Endotrophin, in turn, causes cisplatin resistance. The effects of endotrophin can ...
Roccas Sonia - - 2013
Objective: Research on the structure of the self has mostly developed separately from research on its content. Taking an integrative approach, we studied two structural aspects of the self associated with self-improvement, self-discrepancies and perceived mutability, by focusing on two content areas, traits and values. Studies 1a-1c. Method: 338 students ...
Goetz Christopher G CG Rush University Medical Center, Chicago, IL, USA. - - 2013
E.C. Seguin was one of the early, influential 19th-century neurologists who participated in the development of neurology as a specialty in the United States. Born in France, but raised from early childhood in the United States, Seguin published widely, developed a high-profile New York City practice, and was named Clinical ...
Xue Jiangli - - 2013
The pure natural cotton provides a low-cost material platform for the facile assembly of all-cotton-derived electrochemical supercapacitors (allC-ECs) with a remarkable character of arbitrary foldability and high response rate, which can be bent, rolled-up, and fully folded without loss of high-rate (<50 ms) capacitive performance.
Ichibangase T - - 2013
8-Amino-5-chloro-7-phenylpyrido[3,4-d]pyridazine-1,4(2H,3H)dione (L-012) was recently synthesized as a new chemiluminescence (CL) probe; the light intensity and the sensitivity of L-012 are higher than those of other CL probes such as luminol. Previously, our group developed four lophine-based CL enhancers of the horseradish peroxidase (HRP)-catalyzed CL oxidation of luminol, namely 2-(4-hydroxyphenyl)-4,5-diphenylimidazole (HDI), ...
Ashford Stephen - - 2013
BACKGROUND AND PURPOSE: This paper aimed to select studies evaluating botulinum toxin (BoNT) intervention applied for upper-limb spasticity and from these identify outcome measures that are a) applicable in the hemiparetic upper limb and b) include evaluation of functional outcome in the context of everyday real-life activities. METHODS: A systematic ...
Haponiuk Ireneusz - - 2013
Since 2008 we have performed 10 hybrid procedures for perventricular muscular ventricular septal defects (mVSD) closure. The mean age was 8.5 months (range 2.7 to 17.8), the mean diameter of mVSD was 6.3 mm (range 4 to 10 mm). The postoperative course was uncomplicated and complete closure of the mVSD was accomplished ...
Beasley Spencer W - - 2013
Introduction of an increasingly competence-based Royal Australasian College of Surgeons (RACS) Surgical Education and Training (SET) programme has influenced the nature and conduct of the Fellowship Examination (FEX). The FEX is the final summative assessment taken near the completion of SET training, and is aligned to the other SET assessment ...
Kyriakides T - - 2013
BACKGROUND: Myalgia, defined as any pain perceived in muscle, is very common in the general population and a frequent cause for referral to neurologists, rheumatologists and internists in general. It is however only rarely due to primary muscle disease and often referred from ligaments, joints, bones, the peripheral and central ...
Li Meifang - - 2013
Glycine betaine (GB) can enhance heat tolerance and the accumulation of heat shock protein (HSP) in plants, but the effects of GB on HSP accumulation during salt stress were not previously known. To investigate the mechanism of how GB influences the expression of HSP, wild-type tobacco (Nicotiana tabacum) seedlings pretreated ...
Haino Takeharu - - 2013
Photochromic tris(phenylisoxazolyl)benzene and bispyridine derivatives were mixed in a certain ratio to generate stable gels in benzyl alcohol, 4-methoxybenzyl alcohol, and aniline. Supramolecular assembly of in solution was confirmed by (1)H NMR study. The Tgel value was saturated in a 2 : 3 ratio of and . The intermolecular hydrogen bonds OHN ...
Jiang De-En - - 2013
Thiolated gold nanoclusters form a universe of their own. Researchers in this field are constantly pushing the boundary of this universe by identifying new compositions and in a few "lucky" cases, solving their structures. Such solved structures, even if there are only few, provide important hints for predicting the many ...
< 2 3 4 5 6 7 8 9 10 11 12 >