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Swanson Eric E Swanson Center 11413 Ash Street Leawood, Kan. 66211. - - 2013
Despite the popularity of breast augmentation, limited information is available evaluating this procedure from the patient's perspective. No existing studies assess patient-reported data prospectively in a large number of consecutive patients with a high inclusion rate, as required by evidence-based medicine. This prospective outcome study was undertaken to obtain this ...
Andrews Brian T BT Division of Plastic and Reconstructive Surgery, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095, - - 2013
In newborns with micrognathia and severe upper airway obstruction, understanding potential airway lesions is important for determining appropriate treatment: observation, mandibular distraction, or tracheostomy. When concomitant airway anomalies are present, mandibular distraction is often unsuccessful at alleviating causes of obstruction, mandating the need for tracheostomy. The first part of this ...
Berry Daniel D University of Illinois, Urbana-Champaign, 61820, USA. - - 2013
Evidence suggests that the 7-repeat variant of a 48 base pair variable number tandem repeat polymorphism in the dopamine receptor D4 (DRD4) gene may be associated with the development of attention problems. A parallel literature suggests that genes linked to dopaminergic functioning may be associated with differential sensitivity to context, ...
Pace Meredith M MM Department of Anesthesiology and the Department of Surgery, Division of Plastic Surgery, Dartmouth Hitchcock Medical Center, Dartmouth Geisel School of Medicine, Lebanon, NH 03756, USA. - - 2013
The Practice Advisory on Liposuction published by the American Society of Plastic Surgeons provides a thorough review of anesthetic techniques and guidelines for surgeons who perform liposuction. However, there is evidence to support several changes to the anesthetic infiltrate guidelines that will improve patient safety. These proposed recommendations will have ...
Hu Zhengqing Z Department of Otolaryngology-HNS, Wayne State University, MI, USA. - - 2013
Hearing loss is one of the most common disabilities, affecting approximately 10% of the population. Hair cells and spiral ganglion neurons are usually damaged in most cases of hearing loss. Currently, there is virtually no biological approach to replace damaged hearing cells. Recent developments in stem cell technology provide new ...
Jager Justin J Eunice Kennedy Shriver National Institute for Child Health and Human Development, Bethesda, MD 20892, USA. - - 2013
This study examines historical variation in individual trajectories of heavy drinking and marijuana use from age 18 to 22. Unlike most studies that have examined cohort differences in drug use, it focuses on differences in both level of use and rates of change (growth). Nearly 39,000 youths from the high ...
Ogle Christin M CM Duke University, Durham, NC 27708, USA. - - 2013
The present study examined the specificity of autobiographical memory in adolescents and adults with versus without child sexual abuse (CSA) histories. Eighty-five participants, approximately half of whom per age group had experienced CSA, were tested on the autobiographical memory interview. Individual difference measures, including those for trauma-related psychopathology, were also ...
Shifrin David A DA Jr Department of Cell and Developmental Biology, Vanderbilt University Medical Center, Nashville, TN 37232, - - 2013
Cells communicate with neighboring cells and condition their local environment by secreting soluble factors into the extracellular space. These well-studied facets of cell biology are essential for the establishment and maintenance of physiological homeostasis. However, accumulating evidence has revealed that specific ligands, enzymes, and macromolecules are distributed into the extracellular ...
Lewis Kim K Department of Biology and Antimicrobial Discovery Center, Northeastern University, Boston, Massachusetts 02115, USA. - - 2013
The spread of resistant bacteria, leading to untreatable infections, is a major public health threat but the pace of antibiotic discovery to combat these pathogens has slowed down. Most antibiotics were originally isolated by screening soil-derived actinomycetes during the golden era of antibiotic discovery in the 1940s to 1960s. However, ...
Podzielinski Iwona I Fort Wayne Gynecologic Oncology Center, Fort Wayne, Indiana, - - 2013
SELDI-TOF MS analysis of ovarian cyst fluids revealed that peaks m/z 8696 and 8825 discriminate malignant, borderline, and benign tumors. These peaks correspond to isoforms of apoA2. ELISA demonstrates that apoA1, A2, B, C2, C3, and E cyst fluid concentrations are uncorrelated and higher in malignant ovarian tumors, but only ...
Dickson Eamonn J EJ Department of Physiology and Biophysics, University of Washington, Seattle, WA 98195, - - 2013
Gq-coupled plasma membrane receptors activate phospholipase C (PLC), which hydrolyzes membrane phosphatidylinositol 4,5-bisphosphate (PIP2) into the second messengers inositol 1,4,5-trisphosphate (IP3) and diacylglycerol (DAG). This leads to calcium release, protein kinase C (PKC) activation, and sometimes PIP2 depletion. To understand mechanisms governing these diverging signals and to determine which of ...
Falkenburger Björn H BH Department of Physiology and Biophysics, University of Washington, Seattle, WA 98195, - - 2013
Gq protein-coupled receptors (GqPCRs) of the plasma membrane activate the phospholipase C (PLC) signaling cascade. PLC cleaves the membrane lipid phosphatidylinositol 4,5-bisphosphate (PIP2) into the second messengers diacylgycerol (DAG) and inositol 1,4,5-trisphosphate (IP3), leading to calcium release, protein kinase C (PKC) activation, and in some cases, PIP2 depletion. We determine ...
Baranek Grace T GT University of North Carolina at Chapel Hill, 27599-7122, USA. - - 2013
This cross-sectional study seeks to (a) describe developmental correlates of sensory hyporesponsiveness to social and nonsocial stimuli, (b) determine whether hyporesponsiveness is generalized across contexts in children with autism relative to controls, and (c) test the associations between hyporesponsiveness and social communication outcomes. Three groups of children ages 11-105 months ...
Hyde Luke W LW University of Michigan, Ann Arbor, MI 48109, USA. - - 2013
This study examined dimensions of callous behaviors in early childhood and the role of these behaviors in the development of conduct problems, as well as responsiveness to a family-centered preventative intervention. Caregiver reports of callous behaviors were examined using exploratory and confirmatory factor analysis. Problem behavior was examined using within- ...
Donneys Alexis A University of Michigan Medical School, Pediatric Plastic Surgery Section, 4-730 C.S. Mott Children’s Hospital 1540 E. Hospital Drive Ann Arbor, MI 48109, USA. - - 2013
Therapeutic augmentation of fracture-site angiogenesis with deferoxamine has proven to increase vascularity, callus size, and mineralization in long-bone fracture models. The authors posit that the addition of deferoxamine would enhance pathologic fracture healing in the setting of radiotherapy in a model where nonunions are the most common outcome. Thirty-five Sprague-Dawley ...
Shauver Melissa J MJ Section of Plastic Surgery, Department of Surgery, University of Michigan Health System, Ann Arbor, MI 48109-0340, - - 2013
The Michigan Hand Outcomes Questionnaire has been used to assess a variety of hand and upper extremity injuries and conditions for nearly 15 years. It has been included in several overviews of upper extremity outcomes measures, but it has not been systematically examined regarding its clinometric properties during field trials. ...
Bowes Lucy L King's College London, - - 2013
We investigated the antecedents and consequences of chronic victimization by bullies across a school transition using a genetically sensitive longitudinal design. Data were from the Environmental Risk Longitudinal Twin Study (E-Risk), an epidemiological cohort of 2,232 children. We used mothers' and children's reports of bullying victimization during primary school and ...
Selber Jesse C JC Department of Plastic Surgery, University of Texas M. D. Anderson Cancer Center, Houston, Texas 77030, USA. - - 2013
The widespread use of bioprosthetic mesh in breast reconstruction has revealed an increased risk of seroma and infection, and a high financial cost. This study introduces a technique that mitigates these shortcomings using an autologous dermal graft (Autoderm). Indications, operative technique, and 1-year outcomes are reviewed. Thirty-six breasts in 21 ...
Alperovich Michael M - - 2013
Nipple-sparing mastectomy has gained popularity, but the question remains of whether it can be offered safely to women with a history of reduction mammaplasty or mastopexy. The authors present their experience with nipple-sparing mastectomy in this patient population. Patients at the authors' institution who had reduction mammaplasty or mastopexy before ...
Fischer John P JP Division of Plastic Surgery, Hospital of the University of Pennsylvania, PA 19104, USA. - - 2013
The authors' institution has seen an increase in obese and morbidly obese patients seeking autologous breast reconstruction. The authors provide a comprehensive outcome analysis of patients undergoing abdominally based autologous breast reconstruction. The authors identified obese patients receiving free tissue transfer for breast reconstruction. World Health Organization body mass index ...
Alemany Silvia S Departament Biologia Animal, Facultat Biologia, Universitat de Barcelona, Spain. - - 2013
Little is known about how genetic and environmental factors contribute to the association between parental negativity and behavior problems from early childhood to adolescence. The current study fitted a cross-lagged model in a sample consisting of 4,075 twin pairs to explore (a) the role of genetic and environmental factors in ...
Nelson Charles A CA Boston Children's Hospital, USA. - - 2013
An important function of the brain is to scan incoming sensory information for the presence of relevant signals and act on this information. For humans, the most salient signals are often social in nature, such as the identity and the emotional expression of the faces we encounter in our everyday ...
Lu Gary G Departments of Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA. - - 2013
Methods for plasma cell enrichment of bone marrow (BM) specimens can increase the sensitivity of fluorescence in situ hybridization (FISH) for detecting cytogenomic abnormalities. There are no published reports using these methods to evaluate high-risk cytogenomic abnormalities in patients with plasma cell neoplasms (PCNs) after therapy. To evaluate the utility ...
Herbers Janette E JE University of Minnesota, USA. - - 2013
School mobility has been shown to increase the risk of poor achievement, behavior problems, grade retention, and high school dropout. Using data over 25 years from the Chicago Longitudinal Study, we investigated the unique risk of school moves on a variety of young adult outcomes including educational attainment, occupational prestige, ...
Zhang Delin - - 2013
We investigate the structural stability and magnetic properties of the cubic, tetragonal and hexagonal phases of Mn3Z (Z=Ga, Sn and Ge) Heusler compounds using first-principles density-functional theory. We propose that the cubic phase plays an important role as an intermediate state in the phase transition from the hexagonal to the ...
Grimblat Nicolás - - 2013
The Diels-Alder reactions of simple unsaturated boronates have been investigated using computational methods and the results were compared with those for the analogue dihalo- and dialkylboranes. Our results indicate that the activating effect of the boronate moiety is small. All the studied reactions are concerted normal electron-demand Diels-Alder reactions with ...
Lynnhtun Kyaw - - 2013
A 58-year-old lady presented with mediastinal lymphadenopathy. A thoracoscopic ultrasound-guided fine-needle aspiration showed large atypical epithelioid cells arranged in cohesive sheets and dispersed as single cells with intact cytoplasm amid a background of lymphocytes and histiocytes. A cytological diagnosis of "a malignant neoplasm" was made, raising a broad list of ...
Shi Yun - - 2013
Dose finding for combined drugs has grown rapidly in oncology drug development. The escalation with overdose control (EWOC) method is a popular model-based dose-finding approach to single-agent phase I clinical trials. When two drugs are combined as a treatment, we propose a two-dimensional EWOC design for dose finding on the ...
Zhang Y-H - - 2013
Alzheimer's disease (AD), the most common human neurodegenerative disease, is characterized pathologically by numerous deposits of amyloid plaques in the brain. Systemic administration of clioquinol (CQ) and inoculation with amyloid-beta42 (Aβ42) vaccines have been demonstrated to significantly inhibit deposits of amyloid in AD brains. However, each of these treatments has ...
Zhou Qingxiang - - 2013
Benzoylurea insecticides are a kind of important pesticides and have contributed great to the output of crops. Their residue in environment put serious threats on the human health and environmental safety. Present study established a new, rapid and reliable method for the monitoring of typical benzoylurea insecticides such as diflubenzuron, ...
Burnham S C - - 2013
Dementia is a global epidemic with Alzheimer's disease (AD) being the leading cause. Early identification of patients at risk of developing AD is now becoming an international priority. Neocortical Aβ (extracellular β-amyloid) burden (NAB), as assessed by positron emission tomography (PET), represents one such marker for early identification. These scans ...
Arevalo Ryan Lacdao - - 2013
We show through first-principles calculations that the electronic properties of Pt4 clusters can be tuned by adsorption on substrates with different electronic valence characters. Pt clusters exhibit a metallic character on γ-Al2O3(111) and insulator properties on CaZrO3(001). The noted difference indicates the role of the electronic valence states of the ...
Danescu Adrian - - 2013
Endometrioid or type-I endometrial carcinoma (EC) develops from hyperproliferative glandular pathologies. Inactivation of the tumor suppressor gene PTEN is frequently associated with type-I EC. Using a previously characterized Pten heterozygous (Pten+/-) mouse model, this study investigates the three-dimensional (3D) telomere profiles during progression from hyperplastic lesions to EC to test ...
Zhao Yaguang - - 2013
This article describes the photo-induced living radical polymerization of acrylamides mediated by organo-cobalt porphyrins through photo-cleavage of the Co-C bond to give organic radicals, which propagate polymerization, and cobalt(ii), which is a persistent metal-centered radical. Photo stimulus controls the initiation steps and regulates chain growth by activating the Co-C bond.
Cheng Quan - - 2013
Abstract Aim: To investigate the relation between brain ischemia and persistent vegetative state after severe traumatic brain injury. Methods:The 66 patients with severe brain injury were divided into two groups: The persistent coma group (coma duration >10 days) included 51 patients who had an admission coma score of 5 to 7 ...
Xue Jiangli - - 2013
The pure natural cotton provides a low-cost material platform for the facile assembly of all-cotton-derived electrochemical supercapacitors (allC-ECs) with a remarkable character of arbitrary foldability and high response rate, which can be bent, rolled-up, and fully folded without loss of high-rate (<50 ms) capacitive performance.
Ichibangase T - - 2013
8-Amino-5-chloro-7-phenylpyrido[3,4-d]pyridazine-1,4(2H,3H)dione (L-012) was recently synthesized as a new chemiluminescence (CL) probe; the light intensity and the sensitivity of L-012 are higher than those of other CL probes such as luminol. Previously, our group developed four lophine-based CL enhancers of the horseradish peroxidase (HRP)-catalyzed CL oxidation of luminol, namely 2-(4-hydroxyphenyl)-4,5-diphenylimidazole (HDI), ...
Ashford Stephen - - 2013
BACKGROUND AND PURPOSE: This paper aimed to select studies evaluating botulinum toxin (BoNT) intervention applied for upper-limb spasticity and from these identify outcome measures that are a) applicable in the hemiparetic upper limb and b) include evaluation of functional outcome in the context of everyday real-life activities. METHODS: A systematic ...
Haponiuk Ireneusz - - 2013
Since 2008 we have performed 10 hybrid procedures for perventricular muscular ventricular septal defects (mVSD) closure. The mean age was 8.5 months (range 2.7 to 17.8), the mean diameter of mVSD was 6.3 mm (range 4 to 10 mm). The postoperative course was uncomplicated and complete closure of the mVSD was accomplished ...
Beasley Spencer W - - 2013
Introduction of an increasingly competence-based Royal Australasian College of Surgeons (RACS) Surgical Education and Training (SET) programme has influenced the nature and conduct of the Fellowship Examination (FEX). The FEX is the final summative assessment taken near the completion of SET training, and is aligned to the other SET assessment ...
Kyriakides T - - 2013
BACKGROUND: Myalgia, defined as any pain perceived in muscle, is very common in the general population and a frequent cause for referral to neurologists, rheumatologists and internists in general. It is however only rarely due to primary muscle disease and often referred from ligaments, joints, bones, the peripheral and central ...
Li Meifang - - 2013
Glycine betaine (GB) can enhance heat tolerance and the accumulation of heat shock protein (HSP) in plants, but the effects of GB on HSP accumulation during salt stress were not previously known. To investigate the mechanism of how GB influences the expression of HSP, wild-type tobacco (Nicotiana tabacum) seedlings pretreated ...
Haino Takeharu - - 2013
Photochromic tris(phenylisoxazolyl)benzene and bispyridine derivatives were mixed in a certain ratio to generate stable gels in benzyl alcohol, 4-methoxybenzyl alcohol, and aniline. Supramolecular assembly of in solution was confirmed by (1)H NMR study. The Tgel value was saturated in a 2 : 3 ratio of and . The intermolecular hydrogen bonds OHN ...
Jiang De-En - - 2013
Thiolated gold nanoclusters form a universe of their own. Researchers in this field are constantly pushing the boundary of this universe by identifying new compositions and in a few "lucky" cases, solving their structures. Such solved structures, even if there are only few, provide important hints for predicting the many ...
Schmidt-Edelkraut Udo - - 2013
Cell-fate decisions and differentiation of embryonic and adult neural stem cells (NSC) are tightly controlled by lineage-restricted and temporal factors that interact with cell-intrinsic programs and extracellular signals through multiple regulatory loops. Imprinted genes are important players in neurodevelopment and mental health although their molecular and cellular functions remain poorly ...
Nagel Stefan - - 2013
Chromosomal rearrangements are common features of most cancers, where they contribute to deregulated gene expression. Chromothripsis is a recently described oncogenic mechanism whereby small genomic pieces originating from one chromosomal region undergo massive rearrangements in a single step. Here, we document chromothripsis in Hodgkin lymphoma (HL) cell lines by genomic ...
Holanda L M - - 2013
This work reports on electron spin resonance experiments in oriented single crystals of the hexagonal AlB2 diboride compound (P6/mmm, D16h structure) which display conduction electron spin resonance. The X-band electron spin resonance spectra showed a metallic Dysonian resonance with g-value and intensity independent of temperature. The thermal broadening of the ...
Lee Ki-Ryong - - 2013
We demonstrate a facile controlling of the optical and colorimetric properties of a donor-acceptor conjugated polymer simply by varying the mix ratio of two precursors in a precursor blend. The conversion of a precursor blend results in an entirely new donor-acceptor polymer, distinct from the conjugated polymer of each precursor. ...
Yao Li - - 2013
We report a technique that is based on exchange-induced remnant magnetization for microRNA (miRNA) detection. In sequence-specific exchange reactions between label-free miRNA and magnetically labelled RNA with one mismatched base, the decrease in magnetization quantitatively represents the target miRNA. The detection limit reaches the zeptomole regime, with no amplification or ...
Jaeger Sara R - - 2013
BACKGROUND: A case study with wine where two statistical methods for the analysis of rating-based conjoint analysis data were applied. Traditionally, Ordinary Least Squares (OLS) regression is used to estimate relative importance of the experimental factors and part-worth utilities of factor levels. Partial Least Squares (PLS) regression, which is a ...
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