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Morgan Philip B - - 2013
: To characterize and discover the determinants of the frequency of wear (FOW) of contact lenses. : Survey forms were sent to contact lens fitters in up to 40 countries between January and March every year for 5 consecutive years (2007-2011). Practitioners were asked to record data relating to the ...
Beléndez Vázquez Marina - - 2013
Background: The Work-Family Culture Scale (WFCS) was designed to assess employee perceptions of the extent to which their organizations facilitates a work-family balance. The WFCS comprises three dimensions: Oorganizational time demands, Managerial support and Negative career consequences. Method: The primary purpose of the present study was to analyze the factor ...
Kamioka Hiroharu - - 2013
On the basis of evidence obtained in previous studies, this paper outlines effective music therapy programs for group instructions and the basic contents of exercise and training that the elderly are able to do at home by themselves in their daily lives to reduce the risk of falls. The contents ...
Benoit Amelie - - 2013
This longitudinal study examined personal-accentuation and contextual-amplification models of pubertal timing. In these models, individual and contextual risk factors during childhood and adolescence can magnify the effects of early or late puberty on depression symptoms that occur years later. The moderating role of prepubertal individual factors (emotional problems in late ...
Górriz Plumed Ana B - - 2013
Background: The aim of this study was to analyze the psychometric properties of the Spanish version of the MOOD Questionnaire in child population. This instrument was developed to cover the existing gap in the evaluation of mood in children. Method: The MOOD was administered to 1489 children (mean age= 9.11 ...
Zantingh Alanna J - - 2013
Objective-To determine the effects of hypoglossal nerve block and electrical stimulation of the thyrohyoideus muscles on position of the larynx and hyoid apparatus in resting horses. Animals-16 healthy horses that underwent hypoglossal nerve block and 5 healthy horses that underwent electrical stimulation of the thyrohyoideus muscles. Procedures-Horses underwent bilateral hypoglossal ...
Shaharuddin Bakiah - - 2013
Corneal blindness carries a morbidity that affects quality of life and is often associated with an increased economic burden. In this review, we focus on the severe and painful condition of limbal stem cell deficiency, an important cause of corneal blindness. Conventional corneal transplantation usually results in graft failure and ...
Moriarty Ann T - - 2013
Context.-The College of American Pathologists (CAP) Human Papillomavirus (High-Risk) Survey for Cytopathology and Other Laboratories (CHPV) meets the Clinical Laboratory Improvement Amendments of 1988 (CLIA '88) requirements for 5 proficiency testing challenges analyzed 3 times per year. This study reports laboratory performance for CHPV from 2008 through 2010. Objective.-To identify ...
Tamaoka Akira - - 2013
Neurological disorders are frequently associated with risk factors for falls, such as gait and balance disorders, deficits of lower extremity strength, sensation and coordination, in addition to cognitive impairments. Patients with various kinds of neurological disorders, including Parkinson's disease, Parkinson's syndrome, amyotrophic lateral sclerosis, peripheral neuropathy, stroke, etc, easily suffer ...
Cornish Kim - - 2013
Fragile X syndrome (FXS) has a characteristic cognitive "signature" that by late childhood includes core weaknesses in attention and working memory (WM), but their earlier developmental trajectories remain uncharted. Using a combined cross-sectional and prospective longitudinal design, we tested whether early profiles of attention and WM impairment in FXS indicate ...
Hatipoglu Nevin - - 2013
Although therapeutic first-line approaches have been established in severely immunosuppressed patients with a high risk of invasive fungal infections, treatment modalities for cases with unsatisfactory outcome have not been well defined, especially for the pediatric age gap. Therapy with coadministration of two or three antifungals has been applied by clinicians ...
Topa Gabriela - - 2013
Background: Research on organizational injustice has mainly focused on the victim's perspective. This study attempts to contribute to our understanding of third parties' perspective by empirically testing a model that describes third party reactions to mistreatment of employees. Method: Data were obtained from a sample (N = 334) of Spanish ...
Walker Wade T - - 2013
Objective-To characterize medial femoral condyle (MFC) morphometrics and subchondral bone density patterns in Thoroughbred racehorses and to determine whether these variables differ between left and right limbs. Sample-Stifle joints harvested from 6 Thoroughbred racehorses euthanized for reasons other than hind limb lameness. Procedures-The distal portion of the left and right ...
Paz-Lourido Berta - - 2013
This paper explores the educational factors that underlie the poor collaboration between general practitioners (GPs) and physiotherapists (PTs) in Primary Health Care (PHC), from the GP's perspective. This study was conducted in Majorca, the Balearic Islands (Spain). Participants were nine GPs who graduated from different universities in mainland Spain. A ...
Stock Matthew L - - 2013
Objective-To determine the pharmacokinetics of meloxicam after IV and PO administration to 6 healthy sheep. Animals-6 healthy adult Dorset cross sheep (5 males and 1 female). Procedures-Meloxicam (0.5 mg/kg, IV, or 1.0 mg/kg, PO) was administered in a randomized crossover design with a 10-day washout period. Blood samples were collected ...
De Vlamynck Caroline A - - 2013
Objective-To develop a practical ultrasonography-guided injection approach to anesthetic blockade of the femoral nerve in calves and to assess the method's accuracy. Animals-13 cadavers of 4-week-old male Holstein Friesian calves. Procedures-Detailed topographic and anatomic cross-sectional evaluation of the relevant topography in 3 cadavers was performed to identify optimal injection approaches ...
Diao Hua Jia - - 2013
Aim: Mesenchymal stem cell (MSC)-based therapy presents a promising approach for treating osteoarthritis (OA). However, the molecular interactions between MSCs and OA chondrocytes (OACs) are not known. This study aims to investigate the bidirectional interactions between human MSCs (hMSCs) and human OACs (hOACs) in a 3D co-culture system. Materials & ...
Hollingworth Stephen - - 2013
Single twitch fibers from frog leg muscles were isolated by dissection and micro-injected with furaptra, a rapidly responding fluorescent Ca(2+) indicator. Indicator resting fluorescence (FR) and the change evoked by an action potential (ΔF) were measured at long sarcomere length (16°C); ΔF/FR was scaled to units of ΔfCaD, the change ...
Grubb Søren - - 2013
Members of the TMEM16 (Anoctamin) family of membrane proteins have been shown to be essential constituents of the Ca(2+)-activated Cl(-) channel (CaCC) in many cell types. In this study, we have investigated the electrophysiological properties of mouse TMEM16F. Heterologous expression of TMEM16F in HEK293 cells resulted in plasma membrane localization ...
Robin Gaëlle - - 2013
Depolarization of skeletal muscle fibers induces sarcoplasmic reticulum (SR) Ca(2+) release and contraction that progressively decline while depolarization is maintained. Voltage-dependent inactivation of SR Ca(2+) release channels and SR Ca(2+) depletion are the two processes proposed to explain the decline of SR Ca(2+) release during long-lasting depolarizations. However, the relative ...
Hinnant J Benjamin JB Department of Psychology, Catholic University of America, Washington, DC 20064, USA. - - 2013
We investigated the roles of sex and respiratory sinus arrhythmia (RSA), an index of autonomic parasympathetic nervous system activity, as predictors of codeveloping externalizing and internalizing symptoms in middle childhood. We expected that sex, baseline RSA (RSA-B), and RSA reactivity (RSA-R) to two types of tasks would interact to differentiate ...
Berry Daniel D University of Illinois, Urbana-Champaign, 61820, USA. - - 2013
Evidence suggests that the 7-repeat variant of a 48 base pair variable number tandem repeat polymorphism in the dopamine receptor D4 (DRD4) gene may be associated with the development of attention problems. A parallel literature suggests that genes linked to dopaminergic functioning may be associated with differential sensitivity to context, ...
Hu Zhengqing Z Department of Otolaryngology-HNS, Wayne State University, MI, USA. - - 2013
Hearing loss is one of the most common disabilities, affecting approximately 10% of the population. Hair cells and spiral ganglion neurons are usually damaged in most cases of hearing loss. Currently, there is virtually no biological approach to replace damaged hearing cells. Recent developments in stem cell technology provide new ...
Ogle Christin M CM Duke University, Durham, NC 27708, USA. - - 2013
The present study examined the specificity of autobiographical memory in adolescents and adults with versus without child sexual abuse (CSA) histories. Eighty-five participants, approximately half of whom per age group had experienced CSA, were tested on the autobiographical memory interview. Individual difference measures, including those for trauma-related psychopathology, were also ...
Lewis Kim K Department of Biology and Antimicrobial Discovery Center, Northeastern University, Boston, Massachusetts 02115, USA. - - 2013
The spread of resistant bacteria, leading to untreatable infections, is a major public health threat but the pace of antibiotic discovery to combat these pathogens has slowed down. Most antibiotics were originally isolated by screening soil-derived actinomycetes during the golden era of antibiotic discovery in the 1940s to 1960s. However, ...
Podzielinski Iwona I Fort Wayne Gynecologic Oncology Center, Fort Wayne, Indiana, - - 2013
SELDI-TOF MS analysis of ovarian cyst fluids revealed that peaks m/z 8696 and 8825 discriminate malignant, borderline, and benign tumors. These peaks correspond to isoforms of apoA2. ELISA demonstrates that apoA1, A2, B, C2, C3, and E cyst fluid concentrations are uncorrelated and higher in malignant ovarian tumors, but only ...
Dickson Eamonn J EJ Department of Physiology and Biophysics, University of Washington, Seattle, WA 98195, - - 2013
Gq-coupled plasma membrane receptors activate phospholipase C (PLC), which hydrolyzes membrane phosphatidylinositol 4,5-bisphosphate (PIP2) into the second messengers inositol 1,4,5-trisphosphate (IP3) and diacylglycerol (DAG). This leads to calcium release, protein kinase C (PKC) activation, and sometimes PIP2 depletion. To understand mechanisms governing these diverging signals and to determine which of ...
Falkenburger Björn H BH Department of Physiology and Biophysics, University of Washington, Seattle, WA 98195, - - 2013
Gq protein-coupled receptors (GqPCRs) of the plasma membrane activate the phospholipase C (PLC) signaling cascade. PLC cleaves the membrane lipid phosphatidylinositol 4,5-bisphosphate (PIP2) into the second messengers diacylgycerol (DAG) and inositol 1,4,5-trisphosphate (IP3), leading to calcium release, protein kinase C (PKC) activation, and in some cases, PIP2 depletion. We determine ...
Hyde Luke W LW University of Michigan, Ann Arbor, MI 48109, USA. - - 2013
This study examined dimensions of callous behaviors in early childhood and the role of these behaviors in the development of conduct problems, as well as responsiveness to a family-centered preventative intervention. Caregiver reports of callous behaviors were examined using exploratory and confirmatory factor analysis. Problem behavior was examined using within- ...
Bowes Lucy L King's College London, - - 2013
We investigated the antecedents and consequences of chronic victimization by bullies across a school transition using a genetically sensitive longitudinal design. Data were from the Environmental Risk Longitudinal Twin Study (E-Risk), an epidemiological cohort of 2,232 children. We used mothers' and children's reports of bullying victimization during primary school and ...
Alemany Silvia S Departament Biologia Animal, Facultat Biologia, Universitat de Barcelona, Spain. - - 2013
Little is known about how genetic and environmental factors contribute to the association between parental negativity and behavior problems from early childhood to adolescence. The current study fitted a cross-lagged model in a sample consisting of 4,075 twin pairs to explore (a) the role of genetic and environmental factors in ...
Nelson Charles A CA Boston Children's Hospital, USA. - - 2013
An important function of the brain is to scan incoming sensory information for the presence of relevant signals and act on this information. For humans, the most salient signals are often social in nature, such as the identity and the emotional expression of the faces we encounter in our everyday ...
Lu Gary G Departments of Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA. - - 2013
Methods for plasma cell enrichment of bone marrow (BM) specimens can increase the sensitivity of fluorescence in situ hybridization (FISH) for detecting cytogenomic abnormalities. There are no published reports using these methods to evaluate high-risk cytogenomic abnormalities in patients with plasma cell neoplasms (PCNs) after therapy. To evaluate the utility ...
Herbers Janette E JE University of Minnesota, USA. - - 2013
School mobility has been shown to increase the risk of poor achievement, behavior problems, grade retention, and high school dropout. Using data over 25 years from the Chicago Longitudinal Study, we investigated the unique risk of school moves on a variety of young adult outcomes including educational attainment, occupational prestige, ...
Jager Justin J Eunice Kennedy Shriver National Institute for Child Health and Human Development, Bethesda, MD 20892, USA. - - 2013
This study examines historical variation in individual trajectories of heavy drinking and marijuana use from age 18 to 22. Unlike most studies that have examined cohort differences in drug use, it focuses on differences in both level of use and rates of change (growth). Nearly 39,000 youths from the high ...
Baranek Grace T GT University of North Carolina at Chapel Hill, 27599-7122, USA. - - 2013
This cross-sectional study seeks to (a) describe developmental correlates of sensory hyporesponsiveness to social and nonsocial stimuli, (b) determine whether hyporesponsiveness is generalized across contexts in children with autism relative to controls, and (c) test the associations between hyporesponsiveness and social communication outcomes. Three groups of children ages 11-105 months ...
Fischer John P JP Divisions of Plastic Surgery and Finance, Hospital of the University of Pennsylvania, PA 19104, USA. - - 2013
Choosing a breast reconstructive modality after mastectomy is a critical step involving complex decisions. The authors provide outcomes data comparing two common reconstructive modalities to assist patients and surgeons in preoperative counseling and discussions. A prospectively maintained database was queried identifying select patients undergoing expander/implant and abdominally based free flaps ...
Butterfield Jennifer L JL Women’s Plastic Surgery & Rejuvenation Centre 4750 East Galbraith Road, Suite 215, Cincinnati, Ohio 45236, USA. - - 2013
A 2010 nationwide survey of plastic and reconstructive surgeons indicated that approximately 83 percent performed predominantly implant-based breast reconstruction, with acellular dermal matrix used by approximately half of those practitioners. Although the medical literature documents well over 2000 cases of breast reconstruction with matrices, relatively few cases using other than ...
Krishnan Naveen M NM Geisel School of Medicine at Dartmouth 1 Rope Ferry Road, Hanover, N.H. 03755, USA. - - 2013
The use of acellular dermal matrix has allowed for single-stage immediate breast reconstruction after mastectomy at a significantly decreased cost compared with two-stage expander/implant reconstruction. The use of a pedicled autologous dermal flap in the same fashion as acellular dermal matrix in women with larger, ptotic breasts has also allowed ...
Alperovich Michael M - - 2013
Nipple-sparing mastectomy has gained popularity, but the question remains of whether it can be offered safely to women with a history of reduction mammaplasty or mastopexy. The authors present their experience with nipple-sparing mastectomy in this patient population. Patients at the authors' institution who had reduction mammaplasty or mastopexy before ...
Mallon Peter P Department of Surgery, Institute Curie, Paris, - - 2013
The role of nipple-sparing mastectomy for breast cancer is controversial, as there is concern regarding its oncologic safety and complication rate. The authors reviewed the literature to quantify the incidence of occult nipple malignancy in breast cancer, identify the factors influencing occult nipple malignancy, quantify locoregional recurrence rates, and quantify ...
Chim Harvey H Department of Plastic Surgery and the Department of Pathology, Case Western Reserve University, Cleveland, Ohio 44124, - - 2013
The aim of this study was to compare the incidence of neuroma formation and neuropathic pain following different techniques of nerve ablation in a rat sural nerve model. Rat sural nerve was subjected to four different techniques of ablation with standardized creation of a 1-cm gap (n = 15 in ...
Sugg Kristoffer B KB Section of Plastic and Reconstructive Surgery, Department of Surgery, University of Michigan Health System, F7859 CS Mott Children’s Hospital, 1500 East Medical Center Drive, Ann Arbor, MI 48109-0219, USA. - - 2013
Nonvascularized autologous bone grafts are the criterion standard in craniofacial reconstruction for bony defects involving the craniofacial skeleton. The authors have previously demonstrated that graft microarchitecture is the major determinant of volume maintenance for both inlay and onlay bone grafts following transplantation. This study performs a head-to-head quantitative analysis of ...
Foley Theodore T TT Division of Plastic Surgery, Department of Surgery, Pennsylvania State University, College of Medicine, Hershey, PA 17033, - - 2013
The prominent inflammatory cell identified in excessive scarring is the mast cell. Hypertrophic scar exhibits myofibroblasts derived from the transformation of fibroblasts, increased collagen synthesis, and stationary nonmigratory resident cells. The co-culture of fibroblasts with an established rat mast cell line (RMC-1) was used to explore the hypothesis of whether ...
Rozen Shai S Department of Plastic Surgery, The University of Texas Southwestern Medical Center at Dallas, and the Department of Plastic and Maxillofacial Surgery, Uppsala University Hospital, Dallas, Texas; and Uppsala, Sweden. - - 2013
Single-stage facial reanimation with a partial gracilis muscle coapted to the contralateral facial nerve seems an optimal surgical solution yet has not supplanted the two-stage approach. Insufficient obturator nerve length may limit reach to sizable contralateral facial nerve branches (possibly necessitating interposition nerve grafting), compromise optimal muscle positioning, or risk ...
Vanmierlo Bert B Department of Plastic and Reconstructive Surgery, Brussels University Hospital, Istanbul, - - 2013
The anterolateral thigh flap is currently the frontline choice for head and neck reconstruction. The authors used a chimeric anterolateral thigh flap for reconstruction of a through-and-through oropharyngeal defect. Because of the absence of suitable recipient vessels in the proximity of the defect, the authors recruited the internal mammary vessels. ...
Calder Kevin K Division of Plastic Surgery, Dalhousie University, Queen Elizabeth II Health Sciences Centre, Halifax Infirmary, Halifax, Nova Scotia, - - 2013
The goals of this study are threefold: (1) to determine what effect epinephrine has on the duration of bupivacaine finger block anesthesia; (2) to see whether the duration of action of bupivacaine on digital pain relief is the same duration as numbness to touch/pressure; and (3) to assess the fingertip ...
Andrews Brian T BT Division of Plastic and Reconstructive Surgery, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095, - - 2013
In newborns with micrognathia and severe upper airway obstruction, understanding potential airway lesions is important for determining appropriate treatment: observation, mandibular distraction, or tracheostomy. When concomitant airway anomalies are present, mandibular distraction is often unsuccessful at alleviating causes of obstruction, mandating the need for tracheostomy. The first part of this ...
Spear Scott L SL Department of Plastic Surgery, Georgetown University Hospital, Washington, DC20007 , USA. - - 2013
Although acellular dermal matrix materials have been in use for over a decade in primary and secondary breast reconstruction and in some cosmetic breast surgery, little has been published on the outcomes of these materials for cosmetic applications. A retrospective institutional review board-approved review was conducted of all patients who ...
Aygit Ahmet C AC Bagcilar Research and Training Hospital, Bagcilar, Istanbul, - - 2013
The transaxillary route is a popular method of breast augmentation because it is associated with inconspicuous scars. The subfascial plane carries the advantages and decreases the disadvantages of subglandular and submuscular planes. In the technique described, the authors placed the implant totally subfascially to strengthen the advantages of the traditional ...
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