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Results 551 - 600 of 2977
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Min Y - - 2013
BACKGROUND: The present study aimed to assess the dietary fat intake and blood fatty acid status of healthy Norwegian men and women living in Bergen whose habitual diet is known to be high in long-chain omega-3 fat. METHODS: Healthy men (n = 41) and women (n = 40) aged 20-50 years who were regular blood ...
Kobayashi Masanori - - 2013
In healthy male dogs, peripheral plasma testosterone (T), prostaglandin E2 (PGE2), and seminal plasma PGE2 levels were measured before, during, and after ejaculation and semen quality was examined after oral administration of PGE2. Plasma T and PGE2 levels did not change during these periods, but seminal plasma PGE2 level in ...
Wheeler Lee Adam LA Program in Cellular and Molecular Medicine, Boston Children's Hospital, Boston, Massachusetts, - - 2013
The continued spread of HIV underscores the need to interrupt transmission. One attractive strategy, in the absence of an effective vaccine, is a topical microbicide, but the need for application around the time of sexual intercourse leads to poor patient compliance. Intravaginal (IVAG) application of CD4 aptamer-siRNA chimeras (CD4-AsiCs) targeting ...
Zhou Zhen - - 2013
The nona-Cu(II)-containing tungstoarsenate(iii) [H4{Cu(II)9As(III)6O15(H2O)6}(α-As(III)W9O33)2](8-) () has been synthesized and characterized. Polyanion comprises a unique, cylindrical {Cu(II)9As(III)6O15(H2O)6}(6+) cluster, which forms a large central cavity and is capped on either end by an [α-As(III)W9O33](9-) capping group. It exhibits remarkable activity against K562 leukaemia cells, as well as induces HepG2 cell apoptosis and ...
Bergström Ann-Kristin - - 2013
The aim of this study was to predict the combined effects of enhanced nitrogen (N) deposition and warming on phytoplankton development in high latitude and mountain lakes. Consequently, we assessed, in a series of enclosure experiments, how lake water nutrient stoichiometry and phytoplankton nutrient limitation varied over the growing season ...
Trimboli Pierpaolo - - 2013
OBJECTIVE: Only few studies analyzed the capability of cytology in detecting medullary thyroid cancer (MTC), and they reported a low accuracy of this diagnostic technique. Recently, calcitonin (CT) measurement in aspiration needle washout (FNA-CT) of thyroid and neck lesions has been reported as sensitive tool for MTC. The aim of ...
Calabrò Rocco Salvatore - - 2013
ABSTRACT The aim of the study was to evaluate the prevalence and the etiology of sexual dysfunctions in a group of epileptic outpatients. Sixty Italian men (30 patients and 30 controls), living in Sicily, were enrolled in the study. Our diagnostic investigation included physical and neurological examination, EEG, MRI, and ...
Liu Xue - - 2013
The volatile components of Nigella sativa seeds were isolated using microwave-assisted extraction (MAE) and identified using gas chromatography. Further investigations were carried out to demonstrate the effects of whole extracts on canine (dog) and murine (rat) cytochrome P450 1A (CYP1A). The optimal extraction conditions of MAE were as follows: 25 mL ...
Kargi Atil Y - - 2013
The availability of synthetic recombinant human growth hormone (GH) in potentially unlimited quantities since the 1980s has improved understanding of the many nonstatural effects of GH on metabolism, body composition, physical and psychological function, as well as the consequences of GH deficiency in adult life. Adult GH deficiency is now ...
Howard Lauren E - - 2013
Holocephalans (chimaeras) are a group of marine fishes comprising three families: the Callorhinchidae (callorhinchid fishes), the Rhinochimaeridae (rhinochimaerid fishes) and the Chimaeridae (chimaerid fishes). We have used X-ray microcomputed tomography and magnetic resonance imaging to characterise in detail the nasal anatomy of three species of chimaerid fishes: Chimaera monstrosa, C. ...
Porter Meko - - 2013
A 76-year-old woman presented with 1 month of progressive aphasia, headache, and subsequent right hemiparesis. Initial brain MRI showed a punctate infarct (figure 1, A and C). Susceptibility-weighted imaging was unremarkable. A repeat study 16 days later demonstrated bihemispheric infarcts with multifocal attenuation of intracranial vessels on magnetic resonance angiography ...
Farrer K - - 2013
INTRODUCTION: Almost 60% of elderly care in-patients are at risk of malnutrition. Malnourished patients have poorer clinical outcomes and this is a key factor with respect to prolonging the length of stay. Since 2003, the Malnutrition Universal Screening Tool (MUST) has been advocated as a method for identifying these at-risk ...
Cetin Ceren - - 2013
INTRODUCTION: Being born large for gestational age (LGA) is a risk factor for development of metabolic syndrome (MS) in adolescents and adults. OBJECTIVE: To evaluate prepubertal children born idiopathic LGA to non-obese mothers without gestational diabetes or glucosuria with respect to the presence of MS antecedents. PATIENTS AND METHODS: We ...
Quick V M - - 2013
BACKGROUND: Young adulthood is a stressful transition period that may increase the risk for disturbed eating, especially for college students. The present study aimed to explore disturbed eating behaviours and a broad array of associated psychographic characteristics in a large, diverse sample of college students. METHODS: College students (n = 2604; 58% ...
Liu Peng - - 2013
Medications compounded with isoniazid (INH) are usually applied to surgical sites at the completion of surgery to locally kill postoperative residual tubercle bacilli. However, the distribution and elimination of INH in the vertebrae in vivo are not known. In this study, isotope tracing was used in conjunction with high-pressure liquid ...
Yazer Mark H - - 2013
BACKGROUND: We investigated the effect of implementing adaptive plasma ordering criteria in the computerized physician order entry (CPOE) system, with alerts that were automatically generated if the recipient's antecedent international normalized ratio (INR) did not meet the institutional criteria. STUDY DESIGN AND METHODS: In a regional health care system consisting ...
Schob Alan - - 2013
OBJECTIVES: This retrospective study sought to assess the safety and clinical efficacy of cryoplasty for treatment of side-branch stenoses following main vessel stenting in coronary bifurcation lesions. BACKGROUND: Cryoplasty prevents restenosis by reducing smooth muscle proliferation and extracellular matrix synthesis. Clinical effectiveness has been demonstrated in the peripheral circulation. Treatment ...
Zhang Meide - - 2013
Protein extraction is a crucial step for proteomics studies. To establish an effective protein extraction protocol suitable for 2-DE analysis in Jerusalem artichoke (Helianthus tuberosus L.), three different protein extraction methods-trichloroacetic acid/acetone, Mg/NP-40, and phenol/ammonium acetate methods were evaluated using Jerusalem artichoke leaves as source materials. Of the three methods, ...
Van den Broeck Joyce - - 2013
Although the use of patient-specific surgical guides has gained popularity over the past decade, little research has been done to examine in an objective and qualitative way the fit of such instruments. In this study, we have developed a model to predict the stability of a guide designed to fit ...
Garcia J P JP California Animal Health and Food Safety Laboratory System, San Bernardino Branch, School of Veterinary Medicine, University of California, Davis, San Bernardino, California, - - 2013
Clostridium perfringens type D causes disease in sheep, goats, and other ruminants. Type D isolates produce, at minimum, alpha and epsilon (ETX) toxins, but some express up to five different toxins, raising questions about which toxins are necessary for the virulence of these bacteria. We evaluated the contribution of ETX ...
Bogenschutz Michael P - - 2013
Recent developments in the study of classic hallucinogens, combined with a re-appraisal of the older literature, have led to a renewal of interest in possible therapeutic applications for these drugs, notably their application in the treatment of addictions. This article will first provide a brief review of the research literature ...
Rickels Michael R MR Division of Endocrinology, Diabetes, and Metabolism, Department of Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, USA. - - 2013
The Clinical Islet Transplantation 07 (CIT07) protocol uses antithymocyte globulin and etanercept induction, islet culture, heparinization, and intensive insulin therapy with the same low-dose tacrolimus and sirolimus maintenance immunosuppression as in the Edmonton protocol. To determine whether CIT07 improves engrafted islet β-cell mass, our center measured β-cell secretory capacity from ...
Wikenheiser Andrew M AM Graduate Program in Neuroscience, University of Minnesota, Minneapolis, MN 55455, - - 2013
Laboratory studies of decision making often take the form of two-alternative, forced-choice paradigms. In natural settings, however, many decision problems arise as stay/go choices. We designed a foraging task to test intertemporal decision making in rats via stay/go decisions. Subjects did not follow the rate-maximizing strategy of choosing only food ...
Wisdom Katrina M KM Department of Mechanical Engineering and Materials Science, Duke University, Durham, NC 27708, - - 2013
The self-cleaning function of superhydrophobic surfaces is conventionally attributed to the removal of contaminating particles by impacting or rolling water droplets, which implies the action of external forces such as gravity. Here, we demonstrate a unique self-cleaning mechanism whereby the contaminated superhydrophobic surface is exposed to condensing water vapor, and ...
Li Biqin - - 2013
Sounds deviating from an otherwise repetitive background in some task-irrelevant respect (deviant sounds among standard sounds) capture attention in an obligatory fashion and result in behavioral distraction in an ongoing task. Traditionally, such distraction has been considered as the ineluctable consequence of the deviant sound's low probability of occurrence relative ...
Crane John K JK Department of Medicine, Division of Infectious Diseases, University at Buffalo, Buffalo, New York, USA. - - 2013
Orthopedic surgeons at our institution have noticed an increase in the number of infections due to Propionibacterium acnes, especially following operations on the shoulder. We collected P. acnes isolates from our hospital microbiology laboratory for 1 year and performed antimicrobial susceptibility testing on 28 strains from the shoulder. Antibiotics with ...
Lorenzo Yolanda - - 2013
DNA damage is commonly measured at the level of individual cells using the so-called comet assay (single-cell gel electrophoresis). As the frequency of DNA breaks increases, so does the fraction of the DNA extending towards the anode, forming the comet tail. Comets with almost all DNA in the tail are ...
Kwon Heung Sun HS Section of Retinal Ganglion Cell Biology, Laboratory of Retinal Cell and Molecular Biology, National Eye Institute, National Institutes of Health, Bethesda, Maryland 20892, - - 2013
Myocilin is a secreted glycoprotein that is expressed in ocular and non-ocular tissues. Mutations in the MYOCILIN gene may lead to juvenile- and adult-onset primary open-angle glaucoma. Here we report that myocilin is expressed in bone marrow-derived mesenchymal stem cells (MSCs) and plays a role in their differentiation into osteoblasts ...
Butt Michelle - - 2013
OBJECTIVES: To examine the characteristics of congenital heart disease patients hospitalised with respiratory syncytial virus infection after prophylaxis and determine the associated comorbidities and the incidence of breakthrough respiratory syncytial virus infections. Study design This is a retrospective, single-centre study that was conducted over a period of 7 years. Respiratory ...
Dias Jerry Ray - - 2013
The number of Kekulé resonance structures in a conjugated hydrocarbon is a measure of its singlet ground state and its number of Dewar resonance structures is a measure of the triplet contribution to its ground state. We present a 2-dimensional organized study of rectangular benzenoids having both armchair and zigzag ...
Zhong Yuan Y Molecular and Computational Biology Program, University of Southern California, Los Angeles, CA 90089, - - 2013
DNA damage slows DNA synthesis at replication forks; however, the mechanisms remain unclear. Cdc7 kinase is required for replication origin activation, is a target of the intra-S checkpoint, and is implicated in the response to replication fork stress. Remarkably, we found that replication forks proceed more rapidly in cells lacking ...
Walsh Matthew R - - 2013
Sex and dormancy are intertwined in organisms that engage in asexual and sexual reproduction. The transition between asexual and sexual reproduction typically results in a dormant stage that provides a mechanism for persisting under harsh environmental conditions. For example, many zooplankton engage in sexual reproduction when environmental conditions deteriorate and ...
Riezzo Irene - - 2013
Cardiac muscle necrosis is associated with inflammatory cascade that clears the infarct from dead cells and matrix debris, and then replaces the damaged tissue with scar, through three overlapping phases: the inflammatory phase, the proliferative phase and the maturation phase. Western Blotting, Laser Confocal Microscopy, Raman Microscopy are valuable tools ...
van der Greef Jan - - 2013
Metabolites have played an essential role in our understanding of life, health, and disease for thousands of years. This domain became much more important after the concept of metabolism was discovered. In the 1950s, mass spectrometry was coupled to chromatography and made the technique more application-oriented and allowed the development ...
Rybina Arina - - 2013
Focus on chemical transitions: Epoxidation of a double bond in conjugation to a fluorescent dye was studied at single-molecule level. Direct observation of oxirane formation, indicated as a spectral shift from substrate to product state, revealed an alternative reaction pathway for the epoxidation reaction.
Zhang Zhigao - - 2013
An efficient synthesis of the C1-C21 fragment of azaspiracids-1 and -3 is described. This features a Nozaki-Hiyama-Kishi reaction to couple the AB and CD ring precursors and formation of the THF-fused ABCD trioxadispiroketal system under thermodynamic conditions.
Deymier-Black A C - - 2013
The relationship between the mineralization of peritubular dentin (PTD) and intertubular dentin (ITD) is not well understood. Tubules are quite small, diameter ∼2 µm, and this makes the near-tubule region of dentin difficult to study. Here, advanced characterization techniques are applied in a novel way to examine what organic or nanostructural ...
Bhosale Sheshanath V - - 2013
The supramolecular self-assembly of the core-substituted naphthalene diimide bearing pyridyl motifs leads to the formation of a variety of nanostructures with pH and solvent control. The detection of HCl can be monitored by UV/Vis and fluorescence spectroscopy, as well as the naked eye, with a change in colour (blue to ...
Linden Wolfgang - - 2013
Psychological treatments (PTs) are used as adjuncts to cardiac care. This issue of Psychosomatic Medicine provides a meta-analysis by Rutledge et al. (3) on the effects of PT and cardiac rehabilitation on depression and cardiac outcomes, and the journal recently published a systematic review and meta-regression on a similar topic ...
Zhang Xu - - 2013
Gold nanoparticles (AuNPs) functionalized with thiolated DNA have enabled many studies in nanoscience. The strong thiol/gold affinity and the nanoscale curvature of AuNPs allow the attached DNA to adapt an upright conformation favourable for hybridization. Recently, it has been shown that non-thiolated DNA can also be attached via DNA base ...
Calvo Manuel G - - 2013
We investigated the visual attention patterns (i.e., where, when, how frequently, and how long viewers look at each face region) for faces with (a) genuine, enjoyment smiles (i.e., a smiling mouth and happy eyes with the Duchenne marker), (b) fake, nonenjoyment smiles (a smiling mouth but nonhappy eyes: neutral, surprised, ...
Gromet Dena M DM Operations and Information Management Department, The Wharton School, University of Pennsylvania, Philadelphia, PA 19104, USA. - - 2013
This research demonstrates how promoting the environment can negatively affect adoption of energy efficiency in the United States because of the political polarization surrounding environmental issues. Study 1 demonstrated that more politically conservative individuals were less in favor of investment in energy-efficient technology than were those who were more politically ...
Neary Catherine L - - 2013
Hexokinase II (HK2), the enzyme that catalyzes the first committed step of glycolysis, is overexpressed in many cancers, as is the central signaling kinase Akt. Akt activity promotes HK2 association with the mitochondria, as well as glucose uptake by cancer cells. In HeLa cervical cancer cells, Akt inhibitor IV (Ai4) ...
Craig Benjamin M - - 2013
BACKGROUND: The original SF-6D valuation study collected 3503 standard gambled responses from 611 UK respondents to predict quality-adjusted life year (QALY) values. METHODS: Using 19,980 paired comparison responses from 666 US respondents and a stacked probit model, the 25 coefficients of the original SF-6D multiattribute utility (MAU) regression were estimated, ...
Fisher J E - - 2013
ACCESSIBLE SUMMARY: This paper examines the usage of psychological therapies by mental health nurses. The paper presents the findings from a questionnaire survey of 528 practising mental health nurses in Australia. Key findings include: Mental health nurses believe employing psychological therapies such as cognitive behaviour therapy in their practice will ...
Koyama Tomotsugu - - 2013
Leaf senescence is the final process of leaf development that involves the mobilization of nutrients from old leaves to newly growing tissues. Despite the identification of several transcription factors involved in the regulation of this process, the mechanisms underlying the progression of leaf senescence are largely unknown. Herein, we describe ...
Braunschweig Holger - - 2013
cis-[(Cy3P)2Pt{B(OMe)2}2] () was obtained in quantitative yield and fully characterised. The thermal stability of was investigated in solution using multinuclear NMR spectroscopy revealing a hitherto unknown temperature-dependent equilibrium between and the corresponding starting materials [Pt(PCy3)2] and free B2(OMe)4.
Lerner E Brooke EB Medical College of Wisconsin, Milwaukee , WI 53226, USA. - - 2013
Our objective was to determine the predictive value of the anatomic step of the 2011 Field Triage Decision Scheme for identifying trauma center need. Emergency medical services (EMS) providers caring for injured adults transported to regional trauma centers in three midsized communities were interviewed over two years. Patients were included, ...
Liu Lianlian - - 2013
Symmetric and asymmetric linear trans-bis(tributylphosphine) Pt(ii) bis(acetylide) complexes with functionalized aryl alkynyl ligands (coumarin, naphthalimide and phenyl acetylides) were prepared, which show enhanced absorption in the visible region (molar absorption coefficients up to 76 800 M(-1) cm(-1) at 459 nm) and long-lived triplet excited states (up to 139.9 μs). At room ...
Cao Wei - - 2013
An overwhelming response: The exposure of a supramolecular hydrogel based on a diselenide-containing polymer and a peptide amphiphile containing a drug moiety to γ radiation led to a gel-sol transition owing to the oxidative cleavage of diselenide bonds in the polymer main chain. The hydrogel can also act as a ...
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