Search Results
Results 301 - 350 of 3059
< 2 3 4 5 6 7 8 9 10 11 12 >
Zhu Banghe - - 2013
PURPOSE: Wide-field surgical excision reduces the chance of residual disease, but can also lead to disfigurement and devastating morbidities when resection is close to critical structures. We hypothesize that near-infrared fluorescence (NIRF) imaging can enable accurate detection of tumor margins for image-guided resection. EXPERIMENTAL DESIGN: An orthotopic model of human ...
Goto Masami - - 2013
INTRODUCTION: This study aimed to investigate whether the effect of scanner for cortex volumetry with atlas-based method is reduced using Diffeomorphic Anatomical Registration Through Exponentiated Lie Algebra (DARTEL) normalization compared with standard normalization. METHODS: Three-dimensional T1-weighted magnetic resonance images (3D-T1WIs) of 21 healthy subjects were obtained and evaluated for effect ...
Zeng Gengsheng L - - 2013
Iterative image reconstruction with the total-variation (TV) constraint has become an active research area in recent years, especially in x-ray CT and MRI. Based on Green's one-step-late algorithm, this paper develops a transmission noise weighted iterative algorithm with a TV prior. This paper compares the reconstructions from this iterative TV ...
Qiao Wenli - - 2013
Abstract We evaluated the predictive value of [(18)F] FDG-PET for clinical outcome such as progression-free survival (PFS) and overall survival (OS) in patients with relapsed or refractory DLBCL prior to and after ASCT. (18)F-FDG PET/CT was performed in 39 consecutive relapsed/refractory DLBCL patients scheduled for ASCT. The median follow-up of ...
Allegaert Karel - - 2013
Effective and safe drug administration in neonates should be based on integrated knowledge on the evolving physiological characteristics of the infant who will receive the drug and the pharmacokinetics (PK) and pharmacodynamics (PD) of a given drug. Consequently, clinical pharmacology in neonates is as dynamic and diverse as the neonates ...
Kabalah-Amitai Lee - - 2013
Calcite, aragonite, and vaterite are the three anhydrous polymorphs of calcium carbonate, in order of decreasing thermodynamic stability. Although vaterite is not commonly found in geological settings, it is an important precursor in several carbonate-forming systems and can be found in biological settings. Because of difficulties in obtaining large, pure, ...
Schumann Burkard Gabriela - - 2013
Different life-cycle stages of Trypanosoma brucei are characterized by stage-specific glycoprotein coats. GPEET procyclin, the major surface protein of early procyclic (insect midgut) forms, is transcribed in the nucleolus by RNA polymerase I as part of a polycistronic precursor that is processed to monocistronic mRNAs. In culture, when differentiation to ...
Camacho-Sanchez Miguel - - 2013
Ecological and conservation genetics require sampling of organisms in the wild. Appropriate preservation of the collected samples, usually by cryostorage, is key to the quality of the genetic data obtained. Nevertheless, cryopreservation in the field to ensure RNA and DNA stability is not always possible. We compared several nucleic acid ...
Proffen Benedikt - - 2013
The last few years have witnessed significant advancements in arthroplasty. The procedure is mainly used to treat osteoarthritis of the hip and knee joint. Other joints such as the shoulder or ankle are also being successfully replaced by arthroplasty. The success of the operation depends on the implantation technique as ...
De Jong Anne Margreet - - 2013
Atrial fibrillation (AF) often occurs in the presence of an underlying disease. These underlying diseases cause atrial remodelling, which make the atria more susceptible to AF. Stretch is an important mediator in the remodelling process. The aim of this study was to develop an atrial cell culture model mimicking remodelling ...
Shen Wei-Wei - - 2013
Studies have shown that the expression of CD133, leucine-rich-repeat-containing G-protein-coupled receptor 5 (Lgr5), and ATP binding cassette (ABC)G2 proteins is associated with malignancy and poor prognosis in colon cancer. However, molecular regulation mechanism of the three proteins has not been elucidated. Here, we report that microRNA-142-3p (miR-142-3p) inhibits the expression ...
Wu Tao - - 2013
Copper metal nanoparticles were used as a reducing agent to reduce graphene oxide (GO). The reaction was complete in about 10 min and did not involve the use of any toxic reagents or acids that are typically used in the reduction of GO by Zn and Fe powders. The high reduction ...
Hansen Bjørge Herman - - 2013
OBJECTIVES: The aims of the study were to identify correlates of objectively measured physical activity and to determine whether the explanatory power of the correlates differed with sex, weight status or level of education. METHODS: Physical activity was assessed objectively in 3,867 participants, aged 20-85 years, for a consecutive 7 days using ...
Barone Mariarita - - 2013
The aim of this work was to evaluate the potential anti-inflammatory activity of eleven (5-15) new synthesized derivatives of benzo-thieno[3,2-d]pyrimidine on two cell models, namely human keratinocytes NCTC 2544 and mouse monocyte-macrophages J774. For the synthesis of test compounds an efficient approach was developed: the key isothiocyanate was prepared through ...
Ulm Christina - - 2013
Posttranslational modification of the neural cell adhesion molecule (NCAM) by polysialic acid (polySia) is well studied in the nervous system and described as a dynamic modulator of plastic processes like precursor cell migration, axon fasciculation, and synaptic plasticity. Here, we describe a novel function of polysialylated NCAM (polySia-NCAM) in innate ...
Denkinger Benjamin - - 2013
Planning, predicting, reasoning, and acting often depend crucially on the correct encoding and application of knowledge concerning the temporal and causal ordering of events. Yet no pictorial stimulus set is optimized for investigating the processing of temporal and causal order information. We introduce a novel stimulus set of 265 black-and-white ...
Stoit Astrid M B - - 2013
Different views on the origin of deficits in action chaining in autism spectrum disorders (ASD) have been posited, ranging from functional impairments in action planning to internal models supporting motor control. Thirty-one children and adolescents with ASD and twenty-nine matched controls participated in a two-choice reach-to-grasp paradigm wherein participants received ...
Van Dyke Jonathan M - - 2013
Introduction: Stretch therapy is commonly utilized to prevent shortening maladaptation of skeletal muscle. Stretch in combination with isometric contraction prevents shortening, but the signaling mechanisms are not understood. Methods: Using a soleus tenotomy+stretch rat model, the phosphorylation-activation of mechanosensitive kinases (Akt, p70(S6K) , p38 MAPK, and ERK1/2) were measured for ...
Kawano Shin-Ichiro - - 2013
An efficient synthesis of 2,7-dibromo- and diiodo-pyrene(4,5,8,19)-tetraones led to strong donors and acceptors based on pyrene. They are versatile building blocks for conjugated materials and can be further applied in molecular electronics.
Youngquist J Tyler - - 2013
Microbially synthesized fatty acids are an attractive platform for producing renewable alternatives to petrochemically derived transportation fuels and oleochemicals. Free fatty acids (FFA) are a direct precursor to many high-value compounds that can be made via biochemical and ex vivo catalytic pathways. To be competitive with current petrochemicals, flux through ...
Anderson Megan E - - 2013
BACKGROUND: Complete resection is critical for local control of primary bone sarcomas. Intraoperative consultation, including frozen section of bone marrow margins, frequently is used to aid in this goal. QUESTIONS/PURPOSES: We therefore sought to determine (1) how often intraoperative frozen section of a bone marrow margin correlates with inspection of ...
Aiken M J - - 2013
An eight-year-old male neutered Staffordshire bull terrier was presented for investigation of right forelimb lameness of 14 months' duration. Radiography showed mottled osteolysis of the right radial carpal bone. Histopathology of the bone demonstrated replacement of healthy bone with granulation tissue suggestive of ischaemic necrosis. Lameness resolved following pancarpal arthrodesis. ...
Hollis Christin P - - 2013
PURPOSE: To develop novel hybrid paclitaxel (PTX) nanocrystals, in which bioactivatable (MMPSense® 750 FAST) and near infrared (Flamma Fluor® FPR-648) fluorophores are physically incorporated, and to evaluate their anticancer efficacy and diagnostic properties in breast cancer xenograft murine model. METHODS: The pure and hybrid paclitaxel nanocrystals were prepared by an ...
Liu Pengbo - - 2013
AIMS: To assess human adenoviruses (HAdVs) removal in an advanced wastewater treatment facility and compare two parallel tertiary treatment methods for the removal of HAdVs. METHODS AND RESULTS: Tangential flow ultrafiltration (UF) was used to concentrate the water samples and HAdVs were precipitated by polyethylene glycol. HAdVs were detected only ...
Simpson Kit N - - 2013
BACKGROUND: The ARTEMIS trial compared first-line antiretroviral therapy (ART) with lopinavir/ritonavir (LPV/r) to darunavir plus ritonavir (DRV + RTV) for HIV-1-infected subjects. In order to fully assess the implications of this study, economic modelling extrapolating over a longer term is required. OBJECTIVE: The aim of this study was to simulate the course ...
Duncombe Jennifer - - 2013
OBJECTIVES: To identify the meteorological drivers of dengue vector density and determine high- and low-risk transmission zones for dengue prevention and control in Cairns, Australia. METHODS: Weekly adult female Ae. aegypti data were obtained from 79 double sticky ovitraps (SOs) located in Cairns for the period September 2007-May 2012. Maximum temperature, ...
Watters David A K - - 2013
BACKGROUND: Errors are to be expected in health care. Adverse events occur in around 10% of surgical patients and may be even more common in emergency surgery. There is little formal teaching on surgical error in surgical education and training programmes despite their frequency. METHODS: This paper reviews surgical error ...
Oda Eiji - - 2013
To compare high-sensitivity C-reactive protein (hs-CRP) and white blood cell count (WBC) as a predictor of metabolic syndrome (MetS). Hazard ratios (HRs) adjusted for age, smoking, and other confounding covariates and areas under receiver operating characteristic curve (AUCs) of hs-CRP and WBC for developing MetS were calculated in 1,463 men ...
Sevket Osman - - 2013
Abstract Objective: The goal of this study is to compare the prevalence and clinical outcomes of a one-step with a two-step screening method, both of which are commonly used for diagnosis of GDM. Methods: Women who presented for GDM screening and who consented to participate in this study were randomized ...
Kirchner S - - 2013
Few lethal pathogens in wild-living primates have been described, and little is known about infectious diseases of the reproductive tract and their possible impact on health and reproduction. This report describes the pathology and isolation of an alpha-toxin producing strain of Clostridium septicum in a case of necrotizing endometritis in ...
Van Dung Dinh - - 2013
Two experiments were conducted to determine the effects of crude protein (CP) level in concentrate (experiment 1) and concentrate level (experiment 2) on feed intake, nutrient digestibility, nitrogen (N) retention, ruminal pH and NH3-N concentration and average daily gain (ADG) of Vietnamese local fattening cattle. Animals (24 cattle, initial live ...
Moon Chisook - - 2013
Acinetobacter baumannii is an important cause of postneurosurgical meningitis. The emergence of carbapenem-resistant strains in this setting has caused a therapeutic challenge. We investigated the clinical implications of postneurosurgical meningitis caused by carbapenem-resistant A. baumannii. In this study, we retrospectively reviewed the medical records of patients more than 16 years ...
Lu Fang - - 2013
Rhizoma Dioscoreae Nipponicae (RDN) is a widely used traditional Chinese herb, which is used to treat arthroncus, arthrodynia and arthritis. As is known to us, inflammatory mechanisms have played an important role in the occurrence, course and prognosis of gouty arthritis (GA). The aim of this study was to determine ...
Kimber Joel A - - 2013
Top predators inhabiting a dynamic environment, such as coastal waters, should theoretically possess sufficient cognitive ability to allow successful foraging despite unpredictable sensory stimuli. The cognition-related hunting abilities of marine mammals have been widely demonstrated. Having been historically underestimated, teleost cognitive abilities have also now been significantly demonstrated. Conversely, the ...
Jung Joon-Goo - - 2013
For effective control of foot-and-mouth disease (FMD), the development of rapid diagnostic systems and vaccines are required against its etiological agent, FMD virus (FMDV). To accomplish this, efficient large-scale expression of the FMDV VP1 protein, with high solubility, needs to be optimized. We attempted to produce high levels of a ...
Salem K A - - 2013
Although, several novel forms of intervention aiming at newly identified therapeutic targets are currently being developed for diabetes mellitus (DM), it is well established that physical exercise continues to be one of the most valuable forms of non-pharmacological therapy. The aim of the study was to investigate the effects of ...
Gómez-Martín M Belén - - 2013
This research explores, by means of a questionnaire-based survey, public knowledge and perception as well as the behaviour of young Spanish tourists before, during and after the summer holiday period affected by an episode of extreme heat in 2003. The survey was administered between November and December 2004. The extraordinary ...
Chatterjee Krishanu - - 2013
Bismuth telluride (Bi2Te3) nanorods and polyaniline (PANI) nanoparticles have been synthesized by employing solvothermal and chemical oxidative processes, respectively. Nanocomposites, comprising structurally ordered PANI preferentially grown along the surface of a Bi2Te3 nanorods template, are synthesized using in situ polymerization. X-ray powder diffraction, UV-vis and Raman spectral analysis confirm the ...
Alinejad Yasaman - - 2013
The influence of single-walled carbon nanotubes (SWCNTs) produced by radio frequency (RF) induction thermal plasma with three catalyst mixtures (Ni-Co-Y2 O3 , Ni-Y2 O3 and Ni-Mo-Y2 O3 ) was evaluated on the behavior of murine MC3T3-E1 preosteoblasts. After analyzing SWCNTs properties, mitochondrial enzymatic (MTS) and lactate dehydrogenase (LDH) activities as ...
Kekilli Murat - - 2013
AIM: The aim of this study was to demonstrate that the presence of atypical perinuclear antineutrophil cytoplasmic antibodies (pANCA) in indeterminate colitis (IC) patients and the potential role of pANCA for predicting the patients either with ulcerative colitis (UC) or Crohn's disease (CD) for UC and CD. MATERIAL AND METHODS: ...
Gao Yuan - - 2013
RNase III is a group of dsRNA-specific ribonucleases that play important roles in RNA processing and metabolism. Alr0280 and All4107 in Anabaena sp. PCC7120 are highly similar to RNase III enzymes. In vitro, recombinant Alr0280 showed RNase III activity. In the same cyanobacterium, the expression of ftsH (FtsH protease) could ...
Aragona Pasquale - - 2013
Purpose:  To evaluate the effect of aminoacid enriched artificial tears on the ocular surface of patients with dysfunctional tear syndrome (DTS). Methods:  Forty patients were divided into two groups: group 1 treated for 90 days with sodium hyaluronate (SH) 0.15% 1 drop × 5 times/day; group 2 treated for 90 days with SH 0.15% + aminoacids ...
Campana Davide - - 2013
PURPOSE: Peptide receptor radionuclide therapy (PRRT) is a relatively new treatment modality for patients with unresectable or metastatic gastroenteropancreatic neuroendocrine tumours (GEP NETs). The aim of this study was to determine the time to progression of patients treated with PRRT and to identify the prognostic factors related to treatment response. ...
Lim Matthew S M - - 2013
Cognitive perspectives on gambling propose that biased thinking plays a significant role in sustaining gambling participation and, in vulnerable individuals, gambling problems. One prominent set of cognitive biases include illusions of control involving beliefs that it is possible to influence random gaming events. Sociologists have reported that (some) gamblers believe ...
Susset Eline C - - 2013
To survive unfavorable periods, ladybird beetles form conspicuous aggregations in specific microsites, with these locations remaining the same year after year. This constancy of location leads to the hypothesis that semiochemicals are involved in the attraction and aggregation of ladybirds to the microsite. In this study, we identified two types ...
Lee Jeongmin - - 2013
BACKGROUND: Glaucoma patients with paracentral scotoma are at higher risk of losing central vision than those without glaucoma. The purpose of this study was to determine whether macular inner retinal layer (MIRL) measurements with spectral-domain optical coherence tomography (SD-OCT) outperform circumpapillary retinal nerve fiber layer (cpRNFL) measurements in discriminating between ...
Scartozzi Mario - - 2013
Aims: Altered α6β4 integrin expression has been demonstrated in HER-3-negative tumors and may be responsible for anti-HER treatment resistance. The current study aimed to evaluate the interaction between polymorphisms of α6 and β4 integrins and clinical outcome in HER-3-negative, K-RAS wild-type colorectal cancer patients receiving cetuximab. Patients & methods:K-RAS analysis ...
Huang Y-F - - 2013
The safety of oncolytic viruses, such as conditionally replicative adenoviruses (CRAds), has been validated in clinical trials for cancer therapy. Their antitumor efficacy is limited by the presence of preexisting neutralizing antibodies (NAbs). Mesenchymal stem cells (MSCs) are attractive as a cellular vehicle to carry antitumor agents, not only because ...
Shi Hon-Yi - - 2013
BACKGROUND: The volume-outcome relationship has been validated previously for surgical procedures and cancer treatments. However, no studies have longitudinally compared the relationships between volume and outcome, and none have systematically compared laparoscopic cholecystectomy (LC) surgery outcomes in Taiwan. This study purposed to explore the relationship between volume and hospital treatment ...
Meeson Annette - - 2013
Cardiac side population (CSP) cells, defined by their ability to efflux the vital dye Hoechst 33342, have been identified as putative cardiac stem cells based on their potential to give rise to both cardiomyocytes and endothelial cells. The CSP phenotype relies on an active metabolic pathway and cell viability to ...
< 2 3 4 5 6 7 8 9 10 11 12 >