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Results 201 - 250 of 3079
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da Silva Machado Adriana Gonçalves - - 2013
Introduction. Model for end-stage liver disease (MELD) is an accurate predictor of mortality in patients with cirrhosis, and has been used on liver allocation in Brazil since 2006. However, its impact on organ allocation, waiting list and post-transplant mortality is still poorly characterized. This study aimed to assess the impact ...
Viertel Valentina G - - 2013
OBJECTIVE. The objective of our study was to assess compliance among academic neuroradiologists in reporting institutionally derived critical findings. MATERIALS AND METHODS. We analyzed 3054 neuroradiology CT and MRI reports generated in 1 month. Reports were categorized by whether or not they contained a critical finding based on a previously ...
Cheng Weiwei - - 2013
Dedifferentiated thyroid cancer is often incurable because it does not respond to radioiodine. This study aimed to investigate iodide uptake and the expressions of thyroid-specific molecules after the transfection of human thyrotropin receptor (hTSHR) gene in poorly differentiated follicular thyroid cancer cell line (FTC-133). pGC-FU-hTSHR-GFP-lentivirus and pGC-FU-GFP-lentivirus were added into ...
French Judith C - - 2013
Student empowerment of curriculum changes is a double-edged sword. When examining our third-year surgery course every year, we debate where the line is between improving education through student input against allowing the students to design "an easy course." Written student comments on end-of-course evaluations (from the academic years 2006-2007 to ...
Hug Balthasar L - - 2013
Adrenal incidentalomas (AI) are defined as neoplasias of the adrenal of =/> 1 cm diameter randomly diagnosed in radiographic imaging such as computed tomography (CT) or magnetic resonance imaging (MRI). In literature, their prevalence ranges from 0.81 % to 6 % depending on the cohort and age of patients analyzed. ...
Yang Yujie - - 2013
Taurine, a conditionally essential amino acid, plays a critical role in cardiovascular function. Here we examined the effect of taurine on mitochondria and endoplasmic reticulum in rat cardiomyocytes during glucose deprivation (GD). Data showed that cell viability, intracellular taurine contents, and taurine transporter expression were decreased during GD. In contrast, ...
Galyfos George - - 2013
We conducted a comparison of postoperative cardiac damage, defined as cardiac troponin I (cTn-I) elevation, after carotid endarterectomy in low- and high-risk patients. The Stenting and Angioplasty with Protection in Patients at High Risk for Endarterectomy (SAPPHIRE) criteria for stratifying patients considered for carotid endarterectomy into low and high surgical ...
Madke Bhushan - - 2013
Dermatopathology involves study of the microscopic morphology of skin sections. It mirrors pathophysiologic changes occurring at the microscopic level in the skin and its appendages. Sometimes, we come across certain morphologic features that bear a close resemblance to our physical world. These close resemblances are referred to as "appearances" in ...
Xue Ru - - 2013
Background: With an incidence ranging from 0.01% to 1.0%, renal artery pseudoaneurysm (RAP) is a rare complication after renal biopsy, percutaneous renal surgery, penetrating trauma, and rarely blunt renal trauma. Methods: Percutaneous renal biopsy (PRB) of native kidneys was performed in 1,500 pediatric patients under real-time ultrasonographic guidance at our ...
Lee James A - - 2013
Crizotinib is a first-in-class oral anaplastic lymphoma kinase (ALK) inhibitor targeting ALK-rearranged non-small-cell lung cancer. The therapy was approved by the US FDA in August 2011 and received conditional marketing approval by the European Commission in October 2012 for advanced non-small-cell lung cancer. A break-apart FISH-based assay was jointly approved ...
Wang Hairong - - 2013
The Homo sapiens charged multivesicular body protein 5 (CHMP5) is a member of the multivesicular body, which serves as an anti-apoptotic protein and is thought to participate in leukemogenesis. In this study, a short-hairpin RNA-based RNA interference approach was used to inhibit the expression of CHMP5 in the leukemic cell ...
Beland Michael D MD Department of Diagnostic Imaging, Rhode Island Hospital, Providence, RI 02903, USA. - - 2013
The purpose of this study was to determine the variability of attenuation measurements in a water phantom included in the FOV during multiphase 64-MDCT. Ninety-seven consecutively registered patients undergoing multiphase kidney and liver protocol CT of the abdomen on the same 64-MDCT scanner had a sealed water bottle placed on ...
Gruden James F - - 2013
OBJECTIVE. High resolution CT (HRCT) is diagnostic of usual interstitial pneumonia (UIP) if honeycombing is present. However, biopsy-proven UIP also occurs in patients without honeycombing. Identification of specific HRCT patterns may enable specific diagnosis and allow more patients to enter clinical trials. Pattern may also predict prognosis. We sought to ...
Svoboda Tomislav - - 2013
Reports suggest that repeat users of detoxification services are less likely to get rehabilitated. The goal of this study is to determine rates and predictors of detoxification unit visits among individuals who are chronically homeless with severe drinking problems compared to those who are housed and in the general homeless ...
Feldman Ross D - - 2013
Control rates for hypertension have dramatically improved during the past 2 decades-especially in Canada. However, hypertension remains one of the top risk factors for premature death globally. Furthermore, one-third of Canadians with hypertension have not obtained adequate blood pressure control. Most of these patients have resistant hypertension with uncontrolled blood ...
Kaufman-Shriqui Vered - - 2013
The prevalence and manifestation of posttraumatic stress symptoms in young children may differ from that observed in adults. This study examined sociodemographic, familial, and psychosomatic correlates of posttraumatic stress disorder (PTSD) among preschool children and their mothers who had been exposed to ongoing missile attacks in the Gaza war. One ...
Raina Amit - - 2013
: The distribution of IgG4 plasma cells in colonic mucosa, its significance, and relation to disease activity in patients with inflammatory bowel disease (IBD) is unclear. We systematically evaluated IgG4 cell distribution in colonic mucosal biopsies of patients with IBD and correlated histological findings with disease pattern and mucosal inflammation. ...
Fox Michael G - - 2013
OBJECTIVE. The purpose of this study was to evaluate the lateral mortise approach for performing therapeutic ankle injections. MATERIALS AND METHODS. Fluoroscopically guided ankle joint injections performed from November 2009 through June 2011 using the lateral ankle mortise approach were retrospectively reviewed. Data recorded included age, sex, fluoroscopic time, person ...
Chakravorty Subhajit S MIRECC VISN-4, Philadelphia Veterans Affairs Medical Center, Philadelphia, PA 19104, USA. - - 2013
Patients with alcohol dependence presenting for treatment may have multiple associated co-morbid conditions and limited social supports, which complicate treatment. Each of these factors has been independently associated with complaints of insomnia. In this preliminary study, we investigated the relations between insomnia complaints and socio-demographic factors and psychiatric co-morbidity in ...
Seitz Andrea - - 2013
Adult Alcohol Use Disorders (AUD) patients with Attention Deficit/Hyperactivity Disorder (ADHD) symptoms may suffer more from craving than patients who only have AUD. However, craving may be even more strongly related to withdrawal and psychiatric symptoms; therefore, the association between craving and ADHD may be misinterpreted. The purpose of this ...
Gonzalez Ruben - - 2013
Objectives- To report normative data for the fetal nasal bone length (NBL), frontonasal fold (FNF) thickness, and the FNF/NBL ratio and to study their performance in the sonographic screening of trisomy 21 in a normal, unselected Latin American population. Methods- Women undergoing a routine sonographic examination between 16 and 32 ...
- - 2013
Background. The incidence of liver cirrhosis is significantly high in Latin population. The high prevalence of nonalcoholic fatty liver disease NAFLD is likely partially responsible for these figures. Liver biopsy is not a practical diagnostic option in this scenario. The validation of noninvasive markers of fibrosis is important in populations ...
Kidorf Michael - - 2013
The present study evaluated changes in rates of self-reported heroin and cocaine use in opioid-dependent individuals newly registered to a syringe exchange program (SEP), and examined the effects of recovery-oriented longitudinal variables (i.e., substance abuse treatment, self-help group participation, employment) on changes in drug use. Study participants (n = 240) were opioid-dependent ...
Unruh Kenneth P - - 2013
Patients have identified the knowledge of a physician's level of training as important. Previous studies show equally poor patient's understanding of the medical education hierarchy. Given the importance to the patient and the possible effect on patient satisfaction, it is critical to evaluate patient's understanding of the orthopedic educational hierarchy. ...
Keedy Alexander W AW Department of Radiology and Biomedical Imaging, University of California, San Francisco, CA 94143-0628, - - 2013
The purpose of this article is to investigate the determinants of second-order bile duct visualization at CT cholangiography in living potential liver donors. We retrospectively identified 143 potential living liver donors (83 men and 60 women; mean age, 37 years) evaluated with CT cholangiography, which included a slow infusion of ...
Yeom Kristen W - - 2013
OBJECTIVE. Readout-segmented echo-planar imaging (EPI) has been suggested as an alternative to single-shot EPI for diffusion-weighted imaging (DWI) with reduced distortion. However, clinical comparisons of readout-segmented EPI and EPI DWI are limited by unmatched imaging parameters and reconstruction procedures. Our goal was to compare the clinical utility of generalized autocalibrating ...
Farabee David - - 2013
This study assessed the role of 14 specific relapse-prevention activities and their underlying factors in maintaining abstinence among subjects (N = 302) completing outpatient treatment for stimulant dependence. We examined what broader dimensions might subsume the 14 items constituting the Drug Avoidance Activities checklist (Farabee et al. J Subst Abuse Treat 2002;23:343-350), ...
Park Si Young - - 2013
: This is a prospective study on consecutive patients with acute osteoporotic vertebral compression fractures (OVCFs). : To evaluate the usefulness of magnetic resonance imaging (MRI) for diagnosing appropriate acute lesions before a percutaneous cement augmentation technique. : Vertebral compression fractures related to osteoporosis are very common in the elderly. ...
Berglund Sten - - 2013
This paper presents an analysis of present and future hydrological conditions at the Forsmark site in Sweden, which has been proposed as the site for a geological repository for spent nuclear fuel. Forsmark is a coastal site that changes in response to shoreline displacement. In the considered time frame (until ...
Pudil Radek - - 2013
Introduction. Liver cirrhosis is associated with hyperdynamic circulation which can result in heart failure. Transjugular intrahepatic portosystemic shunt (TIPS) due to increase of cardiac output is a stressful stimulus for cardiovascular system. Therefore, new methods for early detection of heart failure are needed. Transmitral flow is a marker of diastolic ...
Herliczek Thaddeus W - - 2013
OBJECTIVE. The purpose of this study is to examine the utility of appendix MRI in evaluation of pediatric patients with right lower quadrant pain and inconclusive appendix sonography findings. MATERIALS AND METHODS. A search of the radiology electronic database was performed for all appendix MRI examinations performed of pediatric patients ...
Gaitini Diana - - 2013
The feasibility of implementing image subtraction in through-transmission breast sonography was examined. Acoustic mammograms of women with suspicious findings were obtained using through-transmission imaging. Precontrast images were initially acquired. Then a perflutren liquid microsphere contrast agent solution was injected intravenously, and new sets of images were acquired. Precontrast-postcontrast subtraction images ...
D'Arcangelo Manolo - - 2013
Non-small-cell lung cancer (NSCLC) is the leading cause of cancer-related deaths. In the last decade the EGF receptor (EGFR) signaling pathway has emerged as one of the most important molecular aberrations in NSCLC. Drugs interfering with the tyrosine kinase domain of the EGFR (EGFR-TKI), such as erlotinib or gefitinib, demonstrated ...
De Win Gunter - - 2013
To determine, given a fixed amount of training, the optimal distribution of sessions needed to acquire intracorporeal endoscopic suturing skills and to retain said skills for 1 to 6 months. A randomized controlled trial consisted of 6 study groups who received identical laparoscopic suturing training but at differing frequencies of ...
Kautsky Ulrik - - 2013
This is an overview of the strategy used to describe the effects of a potential release from a radioactive waste repository on human exposure and future environments. It introduces a special issue of AMBIO, in which 13 articles show ways of understanding and characterizing the future. The study relies mainly ...
Mariante-Neto Guilherme Mariante-Neto - - 2013
Introduction. A systematic bias against women, resulting from the use of creatinine as a measure of renal function, has been identified in Model for End-stage Liver Disease (MELD)-based liver allocation. Correction of this bias by calculation of female creatinine levels using the Modification of Diet in Renal Disease (MDRD) formula ...
Brown Jeffrey L - - 2013
OBJECTIVE. The objective of this article is to discuss the a radiologist's responsibilities as a mandated reporter of child abuse and the risks in failing to do so. CONCLUSION. All states have established rules that require licensed physicians to report any reasonable suspicion of child abuse. Failure to do so ...
Saindane Amit M AM Department of Radiology and Imaging Sciences, Emory University Hospital, Atlanta, GA 30322, USA. - - 2013
Although often incidental, the "empty" sella turcica can reflect chronically elevated intracranial pressure (ICP). It is particularly common in the setting of idiopathic intracranial hypertension (IIH). This study evaluated which clinical and MRI findings could be used to differentiate patients with chronically elevated ICP from those with incidental empty sella ...
Gryczynski Jan J Friends Research Institute, 1040 Park Avenue, Baltimore, MD 21201, USA. - - 2013
Recent policy initiatives in Baltimore City, MD significantly reduced access disparities between methadone and buprenorphine in the publicly funded treatment sector. This study examines reasons for choosing buprenorphine over methadone among patients with access to both medications. This study was embedded within a larger clinical trial conducted at two outpatient ...
Fathi Mojtaba - - 2013
The radiolabeling of targeting biomolecules with gamma emitter radionuclides for tracing and beta emitters for therapy involves the conjugation of such biomolecules to the chelating agents to form complexes with the radionuclide of interest. In this study, radioconjugate of IGF-1R siRNA with lutetium-177 ((177)Lu) was produced, and the anti-proliferation and ...
Pang John H - - 2013
The "July effect" is a widely discussed phenomenon of worse patient outcomes at teaching hospitals in July due to inexperienced house staff. We conducted a retrospective review of Organ Procurement and Transplantation Network data from Oct 1, 1987 to June 30, 2011, including longitudinal censored data of 360,330 transplantations. Demographic ...
Birdee Gurjeet S GS Division of General Internal Medicine and Pediatrics, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN 37232, USA. - - 2013
To characterize factors associated with physical inactivity among employees with access to workplace wellness program. We examined data on physical inactivity, defined as exercise less than once a week, from the 2010 health risk assessment completed by employees at a major academic institution (N = 16,976). Among employees, 18% of ...
Daltro-Oliveira Renato - - 2013
Introduction. It is known that patients with chronic hepatitis C have a lower health-related quality of life (HRQOL) than the general population and evidence suggests that the hepatitis C virus (HCV) could exert direct neuropathic action on HRQOL. From this perspective, the virus clearance should be accompanied by improvement in ...
Bateni Cyrus P - - 2013
OBJECTIVE. Although much attention is paid to the scapholunate ligament, lunotriquetral ligament, and the triangular fibrocartilage complex, additional intrinsic and extrinsic ligaments in the wrist play an important part in carpal stability. With improved MRI techniques, the radiologist can increasingly visualize these ligaments. CONCLUSION. The anatomy, MRI appearance, and clinical ...
Besra Laxman L Department of Dermatology and STD, Jawaharlal Institute of Postgraduate Medical Education and Research, Pondicherry, - - 2013
Periorbital dermatoses are very common dermatological disorders which pose a diagnostic and therapeutic challenge for the treating dermatologist due to the similarity of symptoms in this area. To study the spectrum of periorbital dermatoses and to assess the association of systemic diseases with periorbital dermatoses. This was a hospital based ...
Di Biagio Antonio - - 2013
Objectives- To investigate common carotid intima-media thickness in a cohort of patients who were vertically infected with human immunodeficiency virus 1 (HIV-1). Methods- We conducted a cross-sectional observational study. Human immunodeficiency virus 1-infected patients were compared with age-, sex-, and body mass index-matched healthy participants. Common carotid intima-media thickness was ...
Erichsen Anders Christian - - 2013
In safety assessments of underground radioactive waste repositories, understanding radionuclide fate in ecosystems is necessary to determine the impacts of potential releases. Here, the reliability of two mechanistic models (the compartmental K-model and the 3D dynamic D-model) in describing the fate of radionuclides released into a Baltic Sea bay is ...
Yang-Sheng Lin - - 2013
Hepatic carcinosarcoma (HCS) is defined as a malignant tumor containing an intimate mixture of carcinomatous and sarcomatous elements. Here, we report the case of a 72-year-old man who developed HCS from an otherwise normal liver. The patient had no history of alcohol abuse or hepatitis B or C infection. An ...
Szucs-Farkas Zsolt - - 2013
OBJECTIVE. The objective of our study was to compare the effect of dual-energy subtraction and bone suppression software alone and in combination with computer-aided detection (CAD) on the performance of human observers in lung nodule detection. MATERIALS AND METHODS. One hundred one patients with from one to five lung nodules ...
Yang Amy - - 2013
Physicians are challenged to effectively treat opioid dependent patients while minimizing diversion of potentially abusable medications, such as buprenorphine. The present study was designed to obtain information on steps physicians report taking to reduce diversion of buprenorphine. National quarterly surveys from 2008 to 2009 of qualified physicians who have prescribed ...
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