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Hirt-Minkowski Patricia - - 2013
Proteinuria is a common incidental finding in primary care. A systematic approach is necessary to differentiate benign causes of proteinuria from severe kidney diseases. Glomerular proteinuria is the predominant pathophysiologic mechanism of the three types of proteinuria (i. e. glomerular, tubular and "overflow") and usually corresponds to urinary protein excretion ...
Yu Shi - - 2013
Background and purpose. The application of nucleos(t)ide analogues in hepatitis B virus (HBV)-related acute-on-chronic liver failure (ACLF) has not yet been widely accepted. Therefore, we conducted a metaanalysis of prospective and retrospective studies to examine the efficacy and safety of nucleos(t)ide analogues in treating HBV-related ACLF. Material and methods. Two ...
Oates M Elizabeth - - 2013
OBJECTIVE. During the 20th century, radiologists enjoyed relationships with clinicians and patients through daily face-to-face communication. As specialist consultants, radiologists were naturally integral members of the care team. CONCLUSION. The widespread availability of information technology, notably PACS, has disrupted the fundamental radiologist-clinician axis. New generations of radiologists must respond to ...
Borja Maria J - - 2013
OBJECTIVE. Our objective is to review the imaging characteristics and applications of conventional and advanced neuroimaging techniques of supratentorial intracranial masses in the pediatric population. Specifically, we review astrocytomas, oligodendrogliomas, primary neuroectodermal tumors, dysembryoplastic neuroepithelial tumors, gangliogliomas, arachnoid cysts, and choroid plexus and pineal region masses. CONCLUSION. Advanced imaging methods, ...
Xie Shao Wei - - 2013
Objectives- The purpose of this study was to evaluate the influence of the serum prostate-specific antigen (PSA) level, prostate volume, and PSA density on prostate cancer detection with contrast-enhanced sonography using contrast-tuned imaging technology compared with baseline imaging (combination of grayscale and power Doppler imaging). Methods- In all, 161 patients ...
Ma Shengchao - - 2013
Hyperhomocysteinemia (HHcy) is a risk factor for cardiovascular disease and has a strong correlation with heart failure. However, the effects of HHcy on cardiac tissue remain less well understood. To elucidate the role of p53-dependent apoptosis in HHcy-induced cardiac injury, we fed ApoE(-/-) mice with high methionine diet to establish ...
Abenavoli Ludovico - - 2013
Non-alcoholic fatty liver disease (NAFLD) is a common and serious disease. Literature reports the central role of the gut-liver axis in the pathogenesis of NAFLD, and recently suggests that the microbiota is a casual factor of the disease, involved in the interactions between intestinal lumen and liver. Probiotic are commensal ...
Woo Sungmin - - 2013
OBJECTIVE. The purpose of this study was to retrospectively assess the prevalence of segmental enhancement inversion of small renal oncocytomas according to tumor size. MATERIALS AND METHODS. Thirty-three patients (19 men, 14 women; mean age, 61 years; range, 40-74 years) with 33 oncocytomas diagnosed at surgical resection who had undergone ...
Chen Baiyu - - 2013
OBJECTIVE. The objective of this study was to evaluate the feasibility of using iterative reconstructions in hepatic CT to improve the precision of Hounsfield unit quantification, which is the degree to which repeated measurements under unchanged conditions provide consistent results. MATERIALS AND METHODS. An anthropomorphic liver phantom with iodinated lesions ...
Asai Satomi - - 2013
Objectives- The purpose of this study was to assess the relationship between the sonographic characteristics of the submandibular glands and organ involvement at the initial presentation in patients with immunoglobulin G4 (IgG4)-related disease. Methods- We conducted a retrospective study that included 15 patients who had bilateral swollen submandibular glands and ...
Hamadani Fadi T - - 2013
The implementation of work hour restrictions across North America have resulted in decreased levels of self injury and medical errors for Residents. An arbitration ruling in Quebec has led to further curtailment of work hours beyond that proposed by the ACGME. This may threaten Resident quality of life and in ...
Lawrence Ryan E - - 2013
Society debates whether addiction is a disease, a response to psychological woundedness, or moral failing. We surveyed a national sample of 1427 US primary care physicians (PCPs) and 487 psychiatrists, asking "In your judgment, to what extent is alcoholism/drug addiction each of the following? A) a disease B) a response ...
Patel Tejas K - - 2013
Background: Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are rare severe cutaneous drug reactions. No large scale epidemiological data are available for this disorder in India. Aims: To carry out a systematic review of the published evidence of the drug-induced SJS and TEN in Indian population. Methods: Publications from ...
Fayssoil Abdallah - - 2013
Objectives- Duchenne muscular dystrophy is an X-linked neuromuscular disorder. The heart is traditionally involved, leading to heart failure. The mdx mouse is a natural animal model of the disease. We conducted a prospective study to analyze left ventricular (LV) function in mdx mice at different ages using high-resolution Doppler echocardiography. ...
Piqué Angels - - 2013
Scenarios of barrier failure and radionuclide release to the near-surface environment are important to consider within performance and safety assessments of repositories for nuclear waste. A geological repository for spent nuclear fuel is planned at Forsmark, Sweden. Conceptual and numerical reactive transport models were developed in order to assess the ...
Tramontano Angela C AC Institute for Technology Assessment, Massachusetts General Hospital, Boston, MA, - - 2013
A subset of patients with stage IA and IB non-small cell lung cancer (NSCLC) is ineligible for surgical resection and undergoes radiation therapy. Radiofrequency ablation (RFA) and stereotactic body radiotherapy are newer potentially attractive alternative therapies. We added RFA and stereotactic body radiotherapy treatment modules to a microsimulation model that ...
Don Steven - - 2013
OBJECTIVE. The purpose of this review is to summarize 10 steps a practice can take to manage radiation exposure in pediatric digital radiography. CONCLUSION. The Image Gently campaign raises awareness of opportunities for lowering radiation dose while maintaining diagnostic quality of images of children. The newest initiative in the campaign, ...
- - 2013
Stage-specific expression of dynein light chain-1 and its interacting kinase, p21-activated kinase-1, in rodent testes: implications in spermiogenesis. Rui-An Wang, Ming Zhao, Marvin L. Meistrich, and Rakesh Kumar. J Histochem Cytochem. 53(10):1235-1243. DOI:10.1369/jhc.5A6688.2005.
Allerton F J W - - 2013
To retrospectively assess the relationship between bronchoalveolar lavage fluid analysis and lung function parameters as assessed by means of barometric whole body plethysmography and airway responsiveness testing in cats with chronic bronchial disease and to evaluate the potential application of barometric whole body plethysmography and airway responsiveness testing to distinguish ...
Zhao Lianxin - - 2013
OBJECTIVE. The objective of our study was to show the feasibility and performance of diffusion-weighted MR neurography (MRN) of extremity nerves with unidirectional motion-probing gradients at 3 T. SUBJECTS AND METHODS. Forty-seven healthy volunteers and 10 patients underwent diffusion-weighted MRN of extremity nerves with unidirectional motion-probing gradients (anterior-posterior direction only) ...
Luyet Cédric - - 2013
Objectives- Sonographic guidance for peripheral nerve anesthesia has proven increasingly successful in clinical practice; however, fears that a change to sonographically guided regional anesthesia may impair the block quality and operating room work flow persist in certain units. In this retrospective cohort study, block quality and patient satisfaction during the ...
Saetre Peter - - 2013
The radiation doses to humans resulting from a potential release of radionuclides from a geological repository for long-lived waste are assessed over tens or even hundreds of thousands of years. Ingestion is expected to be the major exposure pathway, and the group with the highest exposures will be those that ...
Oshri Assaf - - 2013
This study evaluated relations between sexual sensation seeking, co-occurring sex and alcohol use, and sexual risk behaviors (eg, unprotected intercourse and multiple sex partners) among adolescents receiving treatment for substance abuse problems. The ethnically diverse sample included 394 adolescents recruited from outpatient treatment (280 males; Mage  = 16.33 years, SDage  = 1.15). ...
Rai Reena - - 2013
Medical treatments for acne vulgaris include a variety of topical and oral medications. Poor compliance, lack of durable remission, and potential side effects are common drawbacks to these treatments. Therefore, there is a growing demand for a fast, safe, and side-effect-free novel therapy. Acne often improves after exposure to sunlight, ...
Gray Lloyd S - - 2013
Ca(2+) influx at critical points in the cell cycle is required for proliferation. This requirement is so ubiquitous that its occurrence is often treated as background noise. Yet without it, cells stop dividing, suggesting an obvious and potentially effective way to treat cancer. To control proliferation by controlling Ca(2+) influx ...
Meals Clifton - - 2013
Fractures of the tubular bones of the hand are common and potentially debilitating. The majority of these injuries may be treated without an operation. Surgery, however, offers distinct advantages in properly selected cases. We present a review of hand fracture management, with special attention paid to advances since 2008. The ...
Gleeson Margaret - - 2013
Purpose/Objectives: To identify women's information and communication preferences about treatment-focused genetic testing (TFGT) in the ovarian cancer context.Research Approach: A qualitative interview study.Setting: Two familial cancer services and a gynecologic oncology clinic at a major teaching hospital in Australia.Participants: 22 women diagnosed with ovarian cancer who had either advanced disease ...
Merten Christian - - 2013
In the present work, we report a comprehensive vibrational circular dichroism (VCD) spectroscopic study of a chiral crown ether which features an axial chiral 3.3'-diphenyl-1,1'-binaphthyl group as chiral moiety. By comparing the experimental and calculated VCD spectra, we show that the presumably very flexible crown ether preferably adopts only one ...
Alexander Brian M - - 2013
Radiation therapy has been the foundation of therapy following maximal surgical resection in patients with newly diagnosed glioblastoma for decades and the primary therapy for unresected tumors. Using the standard approach with radiation and temozolomide, however, outcomes are poor, and glioblastoma remains an incurable disease with the majority of recurrences ...
Kluge Sebastian - - 2013
Arthrodesis of a painful and destroyed wrist is one of the key operations in patients with rheumatoid arthritis. Clayton is given credit for the first description of an operative technique of wrist arthrodesis by means of an intramedullary Steinmann pin. Mannerfelt popularized this technique by using a Rush pin and ...
Plaza Michael J - - 2013
OBJECTIVE. In this article, we review the most common posterior fossa and suprasellar intracranial neoplasms in the pediatric population. We briefly discuss basic MRI concepts used in the initial evaluation of a pediatric brain tumor and then discuss sophisticated MRI techniques that give insight into the physiology and chemical makeup ...
Shah Rashmi R RR Rashmi Shah Consultancy Ltd., 8 Birchdale, Gerrards Cross, Buckinghamshire SL9 7JA, UK. - - 2013
The development of tyrosine kinase inhibitors (TKI) represents a major milestone in oncology. However, their use has been found to be associated with serious toxicities that impinge on various vital organs including the heart. Sixteen TKIs have been approved for use in oncology as of 30 September 2012, and a ...
Victoria Teresa - - 2013
OBJECTIVE. Prenatal diagnosis of skeletal dysplasia is often difficult and based on findings with ultrasound, a technique with 40-60% sensitivity. The purpose of this study was to evaluate a preliminary experience in assessing severe prenatal osseous abnormalities with low-dose fetal CT. The hypothesis was that use of CT may improve ...
Chae Eun Young - - 2013
OBJECTIVE. The purpose of our study was to assess the diagnostic performance of breast MRI in evaluating residual disease in patients after excisional biopsy for breast cancer on the basis of both morphologic and kinetic features. MATERIALS AND METHODS. Of 5304 breast MRI examinations performed between January 2007 and December ...
Sandlin Adam T - - 2013
Polyhydramnios is an excessive amount of amniotic fluid within the amniotic cavity. The etiology of polyhydramnios may be idiopathic, the consequence of fetal structural anomalies, or the consequence of various fetal and maternal conditions. The clinical importance of polyhydramnios is found in its association with adverse pregnancy outcomes and the ...
Nathan Carl - - 2013
Reactive oxygen species (ROS) react preferentially with certain atoms to modulate functions ranging from cell homeostasis to cell death. Molecular actions include both inhibition and activation of proteins, mutagenesis of DNA and activation of gene transcription. Cellular actions include promotion or suppression of inflammation, immunity and carcinogenesis. ROS help the ...
Ryan Caitriona - - 2013
The intermittent use of dilute sodium hypochlorite "bleach baths" has shown efficacy as adjunctive therapy for atopic dermatitis (AD). This feasibility study evaluated the clinical response and patient acceptability of treatment with a cleansing body wash containing sodium hypochlorite in children with AD. This was a 12-week open-label feasibility study ...
Berglund Sten - - 2013
This paper describes solute transport modeling carried out as a part of an assessment of the long-term radiological safety of a planned deep rock repository for spent nuclear fuel in Forsmark, Sweden. Specifically, it presents transport modeling performed to locate and describe discharge areas for groundwater potentially carrying radionuclides from ...
Hirayuki Enomoto - - 2013
Background. The relationships between the metabolic parameters and the endoscopic findings of esophageal varices have been poorly investigated. We investigated the association of the branched-chain amino acids to tyrosine ratio (BTR) with the severity of liver fibrosis and esophageal varices. Material and methods. We studied hepatitis C virus (HCV)-positive chronic ...
Chudakoff Jeffrey H - - 2013
OBJECTIVE. The purpose of this study was to determine the reach, appeal, and learning effectiveness of a Web-based pediatric radiology curriculum with attention to level of training, test format, program size, subspecialty, and country of study. MATERIALS AND METHODS. Registration demographics, the 10-point evaluation form, and pre- and posttest scores ...
Wei Shu-Qin - - 2013
The objective of the study was to examine the associations of maternal plasma levels of 25-hydroxyvitamin D [25(OH)D] with angiogenesis and endothelial dysfunction indicators: soluble fms-like tyrosine kinase-1 (sFlt-1), placental growth factor (PlGF), intercellular adhesion molecule-1 (ICAM-1), vascular adhesion molecule-1 (VCAM-1), and risk of preeclampsia. In this prospective cohort study ...
Huang Yu-Len - - 2013
Because malignant and benign breast tumors show different shapes and sizes on sonography, information about tumor shapes and sizes is important for clinical diagnosis. Since sonograms include noise and tissue texture, accurate clinical diagnosis is highly dependent on clinical experience and expertise. However, manually sketching a 3-dimensional (3D) breast tumor ...
Yang Rachel L - - 2013
The virtual patient (VP) is a web-based tool that allows students to test their clinical decision-making skills using simulated patients. Three VP cases were developed using commercially available software to simulate common surgical scenarios. Surgical clerks volunteered to complete VP cases. Upon case completion, an individual performance score (IPS, 0-100) ...
Lindborg Tobias - - 2013
Understanding how long-term abiotic and biotic processes are linked at a landscape level is of major interest for analyzing future impact on humans and the environment from present-day societal planning. This article uses results derived from multidisciplinary work at a coastal site in Sweden, with the aim of describing future ...
Wunsch Ewa - - 2013
Introduction. Hyponatremia is associated with high mortality and predicts hepatic encephalopathy but its effect on health-related quality of life remains to be established. Material and methods. In this study we prospectively analyzed the relationship between hyponatremia, clinical features and quality of life in a cohort of 116 patients with cirrhosis. ...
Wang Carolyn L - - 2013
OBJECTIVE. Metastatic breast cancer in internal mammary (IM) lymph nodes is associated with a poor prognosis. This study correlates (18)F-FDG PET/CT-positive IM lymph nodes with ultrasound-guided fine-needle aspiration (FNA) cytopathologic results and determines risk factors for IM node positivity on PET/CT. MATERIALS AND METHODS. For this retrospective study, a database ...
Gün Ismet - - 2013
Objectives- Our aim was to evaluate whether the presence of an amniotic sheet affects obstetric and neonatal outcomes. Methods- : All singleton pregnant women with and without a sonographic diagnosis of an amniotic sheet between the 16th and 24th weeks of pregnancy were retrospectively identified. Two women without an amniotic ...
Grewal Perbinder - - 2013
Accurate and legible record keeping is a crucial part of good medical practice. Surgical Hospital Audit of Record Keeping (SHARK) is a new audit and teaching tool for junior doctors. The author has designed the tool, based on the Royal College of Surgeons guidelines, to anonymously score the different surgical ...
Leuppi Jörg D - - 2013
Computed tomography (CT) is an important and increasingly employed tool for investigating acute and chronic thoracic symptoms such as cough, shortness of breath and chest pain. The differential diagnosis is large - from cardiac diseases, parenchymal lung dieseases, pulmonary embolism and aortic dissection through to neurological, spinal and musculoskeletal conditions. ...
Näslund Jens-Ove - - 2013
For a deep geological repository for spent nuclear fuel planned in Sweden, the safety assessment covers up to 1 million years. Climate scenarios range from high-end global warming for the coming 100 000 years, through deep permafrost, to large ice sheets during glacial conditions. In contrast, in an existing repository for short-lived waste ...
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