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Results 101 - 150 of 3060
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Gonzalez Ruben - - 2013
Objectives- To report normative data for the fetal nasal bone length (NBL), frontonasal fold (FNF) thickness, and the FNF/NBL ratio and to study their performance in the sonographic screening of trisomy 21 in a normal, unselected Latin American population. Methods- Women undergoing a routine sonographic examination between 16 and 32 ...
Lawrence Ryan E - - 2013
Society debates whether addiction is a disease, a response to psychological woundedness, or moral failing. We surveyed a national sample of 1427 US primary care physicians (PCPs) and 487 psychiatrists, asking "In your judgment, to what extent is alcoholism/drug addiction each of the following? A) a disease B) a response ...
Patel Tejas K - - 2013
Background: Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are rare severe cutaneous drug reactions. No large scale epidemiological data are available for this disorder in India. Aims: To carry out a systematic review of the published evidence of the drug-induced SJS and TEN in Indian population. Methods: Publications from ...
Fayssoil Abdallah - - 2013
Objectives- Duchenne muscular dystrophy is an X-linked neuromuscular disorder. The heart is traditionally involved, leading to heart failure. The mdx mouse is a natural animal model of the disease. We conducted a prospective study to analyze left ventricular (LV) function in mdx mice at different ages using high-resolution Doppler echocardiography. ...
Torudd Jesper - - 2013
This study investigates whether non-human biota are protected against harmful effects of ionizing radiation after a possible future release of radioactive matter from a planned repository for spent nuclear fuel. Radiation dose rates to a broad spectrum of organisms were calculated based on data from sampled organisms and modeled activity ...
Lakshmi Chembolli - - 2013
Underlying hormone imbalances may render acne unresponsive to conventional therapy. Relevant investigations followed by initiation of hormonal therapy in combination with regular anti-acne therapy may be necessary if signs of hyperandrogenism are present. In addition to other factors, androgen-stimulated sebum production plays an important role in the pathophysiology of acne ...
Miyamoto Masahito - - 2013
Peritonitis is still the major complication associated with peritoneal dialysis (PD). Microbacterium spp., a type of coryneform bacteria, is an environmental bacterium isolated from soil, waste water and animals. Human infection is rare, and only few cases have so far been reported in immunocompromised hosts, such as PD patients. Microbacterium ...
Bjerklund Johansen Truls E - - 2013
Radiotherapy is the main salvage option after primary radical prostatectomy. Radical prostatectomy, cryosurgical ablation and high-intensity focused ultrasound are the main salvage options after primary radiotherapy. After primary radiotherapy, long-term oncological outcome of salvage radical prostatectomy and salvage cryosurgical ablation is fairly comparable with the results of primary radical prostatectomy ...
Kautsky Ulrik - - 2013
This is an overview of the strategy used to describe the effects of a potential release from a radioactive waste repository on human exposure and future environments. It introduces a special issue of AMBIO, in which 13 articles show ways of understanding and characterizing the future. The study relies mainly ...
Mariante-Neto Guilherme Mariante-Neto - - 2013
Introduction. A systematic bias against women, resulting from the use of creatinine as a measure of renal function, has been identified in Model for End-stage Liver Disease (MELD)-based liver allocation. Correction of this bias by calculation of female creatinine levels using the Modification of Diet in Renal Disease (MDRD) formula ...
Brown Jeffrey L - - 2013
OBJECTIVE. The objective of this article is to discuss the a radiologist's responsibilities as a mandated reporter of child abuse and the risks in failing to do so. CONCLUSION. All states have established rules that require licensed physicians to report any reasonable suspicion of child abuse. Failure to do so ...
Gryczynski Jan - - 2013
Recent policy initiatives in Baltimore City, MD significantly reduced access disparities between methadone and buprenorphine in the publicly funded treatment sector. This study examines reasons for choosing buprenorphine over methadone among patients with access to both medications. This study was embedded within a larger clinical trial conducted at two outpatient ...
Fathi Mojtaba - - 2013
The radiolabeling of targeting biomolecules with gamma emitter radionuclides for tracing and beta emitters for therapy involves the conjugation of such biomolecules to the chelating agents to form complexes with the radionuclide of interest. In this study, radioconjugate of IGF-1R siRNA with lutetium-177 ((177)Lu) was produced, and the anti-proliferation and ...
Pang John H - - 2013
The "July effect" is a widely discussed phenomenon of worse patient outcomes at teaching hospitals in July due to inexperienced house staff. We conducted a retrospective review of Organ Procurement and Transplantation Network data from Oct 1, 1987 to June 30, 2011, including longitudinal censored data of 360,330 transplantations. Demographic ...
Saetre Peter - - 2013
The radiation doses to humans resulting from a potential release of radionuclides from a geological repository for long-lived waste are assessed over tens or even hundreds of thousands of years. Ingestion is expected to be the major exposure pathway, and the group with the highest exposures will be those that ...
Oshri Assaf - - 2013
This study evaluated relations between sexual sensation seeking, co-occurring sex and alcohol use, and sexual risk behaviors (eg, unprotected intercourse and multiple sex partners) among adolescents receiving treatment for substance abuse problems. The ethnically diverse sample included 394 adolescents recruited from outpatient treatment (280 males; Mage  = 16.33 years, SDage  = 1.15). ...
Rai Reena - - 2013
Medical treatments for acne vulgaris include a variety of topical and oral medications. Poor compliance, lack of durable remission, and potential side effects are common drawbacks to these treatments. Therefore, there is a growing demand for a fast, safe, and side-effect-free novel therapy. Acne often improves after exposure to sunlight, ...
Gray Lloyd S - - 2013
Ca(2+) influx at critical points in the cell cycle is required for proliferation. This requirement is so ubiquitous that its occurrence is often treated as background noise. Yet without it, cells stop dividing, suggesting an obvious and potentially effective way to treat cancer. To control proliferation by controlling Ca(2+) influx ...
Meals Clifton - - 2013
Fractures of the tubular bones of the hand are common and potentially debilitating. The majority of these injuries may be treated without an operation. Surgery, however, offers distinct advantages in properly selected cases. We present a review of hand fracture management, with special attention paid to advances since 2008. The ...
Gleeson Margaret - - 2013
Purpose/Objectives: To identify women's information and communication preferences about treatment-focused genetic testing (TFGT) in the ovarian cancer context.Research Approach: A qualitative interview study.Setting: Two familial cancer services and a gynecologic oncology clinic at a major teaching hospital in Australia.Participants: 22 women diagnosed with ovarian cancer who had either advanced disease ...
Avila Rodolfo - - 2013
Assessments of radiological impacts on humans and other biota from potential releases to the biosphere from a deep geologic repository for spent nuclear fuel are associated with several challenges. Releases, if any, will likely occur in a far future and to an environment that will have experienced substantial transformations. Such ...
Price Timothy J - - 2013
The medical treatment of colorectal cancer (CRC) has evolved greatly in the last 10 years, involving complex combined chemotherapy protocols and, in more recent times, new biologic agents. Advances in adjuvant therapy have been limited to the addition of oxaliplatin and the substitution of oral fluoropyrimidine (e.g., capecitabine) for intravenous 5-fluorouracil ...
Neuhaus Valentin - - 2013
Traumatic bone loss in hand surgery is challenging for the patient as well as the doctor. Whereas the patient is threatened with a possible amputation or severe disability, the hand surgeon focuses on reconstruction, restoration of the function, bony union, and appearance of the injured hand. Both are confronted with ...
Almajhdi Fahad N - - 2013
Background/Aims. This study investigated how HBV replication and host immune response are effected by reduced expression of TGF-β1 and HBx. Material and methods. Short interfering RNA (siRNA) knockdown technology has been used to examine the role of TGF-β1 in hepatitis B virus replication. The siTGF-β1 has been transfected along with ...
Ganjoo Shikhar - - 2013
Background: Intralesional corticosteroids are the treatment of choice for adults with less than 50% of scalp area involvement with alopecia areata. The sensitivity of picking up clinical response to treatment by clinical examination is very variable and has inter individual variation. Aims: To evaluate the efficacy of intralesional triamcinolone acetonide ...
Kanaan Yassine - - 2013
Objectives- The purpose of this study was to determine whether any sonographic features of jumper's knee can predict the outcome after sonographically guided percutaneous patellar tendon fenestration. Methods- Patients were identified between July 2001 and March 2009 who had clinical and sonographic findings of jumper's knee, who had failed conservative ...
Huang Andrew T - - 2013
OBJECTIVES/HYPOTHESIS: Delayed lower cranial neuropathy is a rare complication following primary radiotherapy for head and neck cancer, and has been most associated with nasopharyngeal carcinoma with minimal data regarding this outcome in the treatment of the oropharynx. No reports, to the authors' knowledge, have described this complication following intensity modulated ...
Berglund Sten - - 2013
This paper presents an analysis of present and future hydrological conditions at the Forsmark site in Sweden, which has been proposed as the site for a geological repository for spent nuclear fuel. Forsmark is a coastal site that changes in response to shoreline displacement. In the considered time frame (until ...
Pudil Radek - - 2013
Introduction. Liver cirrhosis is associated with hyperdynamic circulation which can result in heart failure. Transjugular intrahepatic portosystemic shunt (TIPS) due to increase of cardiac output is a stressful stimulus for cardiovascular system. Therefore, new methods for early detection of heart failure are needed. Transmitral flow is a marker of diastolic ...
Herliczek Thaddeus W - - 2013
OBJECTIVE. The purpose of this study is to examine the utility of appendix MRI in evaluation of pediatric patients with right lower quadrant pain and inconclusive appendix sonography findings. MATERIALS AND METHODS. A search of the radiology electronic database was performed for all appendix MRI examinations performed of pediatric patients ...
Gaitini Diana - - 2013
The feasibility of implementing image subtraction in through-transmission breast sonography was examined. Acoustic mammograms of women with suspicious findings were obtained using through-transmission imaging. Precontrast images were initially acquired. Then a perflutren liquid microsphere contrast agent solution was injected intravenously, and new sets of images were acquired. Precontrast-postcontrast subtraction images ...
D'Arcangelo Manolo - - 2013
Non-small-cell lung cancer (NSCLC) is the leading cause of cancer-related deaths. In the last decade the EGF receptor (EGFR) signaling pathway has emerged as one of the most important molecular aberrations in NSCLC. Drugs interfering with the tyrosine kinase domain of the EGFR (EGFR-TKI), such as erlotinib or gefitinib, demonstrated ...
De Win Gunter - - 2013
To determine, given a fixed amount of training, the optimal distribution of sessions needed to acquire intracorporeal endoscopic suturing skills and to retain said skills for 1 to 6 months. A randomized controlled trial consisted of 6 study groups who received identical laparoscopic suturing training but at differing frequencies of ...
Winzeler Bettina - - 2013
Hyponatremia is the most common electrolyte disturbance and thus a common "incidental laboratory finding" in hospitalized as well as ambulatory patients. Acute hyponatremia mostly causes clear neurological symptoms. In contrast, mild chronic hyponatremia is often characterized by only mild and unspecific symptoms like fatigue, vertigo or slight confusion. Importantly, recent ...
Piqué Angels - - 2013
Scenarios of barrier failure and radionuclide release to the near-surface environment are important to consider within performance and safety assessments of repositories for nuclear waste. A geological repository for spent nuclear fuel is planned at Forsmark, Sweden. Conceptual and numerical reactive transport models were developed in order to assess the ...
Kumari Rashmi - - 2013
There is increasing evidence in support of the interplay of growth hormone (GH), insulin, and insulin-like growth factor-1 (IGF-1) signaling during puberty, which have a causal role in pathogenesis of acne by influencing adrenal and gonadal androgen metabolism. Milk consumption and hyperglycemic diets can induce insulin and IGF-1-mediated PI3K ⁄ ...
Kaplan Megan C - - 2013
The purpose of this series is to describe the grayscale and color Doppler sonographic characteristics as well as the histopathologic features of rare solid posterior neck masses identified on prenatal sonography in pregnant patients. We conducted a retrospective review of detailed fetal sonographic examinations of second- and third-trimester pregnancies referred ...
Brandes Alba A - - 2013
Deciding upon the therapeutic approach for patients with recurrent glioblastoma is a challenge. Although second surgery may provide effective palliation, it has yet to be established whether it prolongs survival and/or improves quality of life; nor have data been reported in literature to demonstrate that repeat surgery is indicated for ...
Adani Roberto - - 2013
Amputation at the proximal phalanx or at the metacarpophalangeal joint can be treated by pollicization of a finger, osteoplastic reconstruction, free microvascular transfer of a toe, or distraction lengthening. The best technique to use to treat these cases depends on the place of amputation and the patient's age, sex, occupation ...
Neuss Michael N - - 2013
In 2009, the American Society of Clinical Oncology (ASCO) and the Oncology Nursing Society (ONS) published standards for the safe use of parenteral chemotherapy in the outpatient setting, including issues of practitioner orders, preparation, and administration of medication. In 2011, these were updated to include inpatient facilities. In December 2011, ...
Lindborg Tobias - - 2013
Understanding how long-term abiotic and biotic processes are linked at a landscape level is of major interest for analyzing future impact on humans and the environment from present-day societal planning. This article uses results derived from multidisciplinary work at a coastal site in Sweden, with the aim of describing future ...
Wunsch Ewa - - 2013
Introduction. Hyponatremia is associated with high mortality and predicts hepatic encephalopathy but its effect on health-related quality of life remains to be established. Material and methods. In this study we prospectively analyzed the relationship between hyponatremia, clinical features and quality of life in a cohort of 116 patients with cirrhosis. ...
Wang Carolyn L - - 2013
OBJECTIVE. Metastatic breast cancer in internal mammary (IM) lymph nodes is associated with a poor prognosis. This study correlates (18)F-FDG PET/CT-positive IM lymph nodes with ultrasound-guided fine-needle aspiration (FNA) cytopathologic results and determines risk factors for IM node positivity on PET/CT. MATERIALS AND METHODS. For this retrospective study, a database ...
Gün Ismet - - 2013
Objectives- Our aim was to evaluate whether the presence of an amniotic sheet affects obstetric and neonatal outcomes. Methods- : All singleton pregnant women with and without a sonographic diagnosis of an amniotic sheet between the 16th and 24th weeks of pregnancy were retrospectively identified. Two women without an amniotic ...
Grewal Perbinder - - 2013
Accurate and legible record keeping is a crucial part of good medical practice. Surgical Hospital Audit of Record Keeping (SHARK) is a new audit and teaching tool for junior doctors. The author has designed the tool, based on the Royal College of Surgeons guidelines, to anonymously score the different surgical ...
Leuppi Jörg D - - 2013
Computed tomography (CT) is an important and increasingly employed tool for investigating acute and chronic thoracic symptoms such as cough, shortness of breath and chest pain. The differential diagnosis is large - from cardiac diseases, parenchymal lung dieseases, pulmonary embolism and aortic dissection through to neurological, spinal and musculoskeletal conditions. ...
Blumfield Einat - - 2013
OBJECTIVE. Acute appendicitis is the most common condition requiring emergency surgery in children. Differentiation of perforated from nonperforated appendicitis is important because perforated appendicitis may initially be managed conservatively whereas nonperforated appendicitis requires immediate surgical intervention. CT has been proved effective in identifying appendiceal perforation. The purpose of this study ...
Seiffge David - - 2013
Alone a carotid bruit by itself may have limited clinical value. If a physician hears a carotid bruit by auscultation, it may lead to further exams, such as neurovascular ultrasound, what will eventually disclose an asymptomatic stenosis of the carotid artery. For this purpose the auscultation may reach specificity values ...
Krähenbühl Stephan - - 2013
Elevated transaminases in asymptomatic patients can be detected in more than 5 % of the investigations. If there are no obvious reasons, the finding should be confirmed within the next 3 months. Frequent causes are non-alcoholic fatty liver disease (NAFLD), non-alcoholic steatohepatitis (NASH), alcohol, hepatitis B or C, hemochromatosis and ...
Go Michael R - - 2013
The midaortic syndrome (MAS) refers to descending thoracic and abdominal aortic coarctation, which is rare and most common in the pediatric population. Open surgical repair, often with aortoaortic bypass, remains a highly effective treatment and is traditionally thought to be definitive despite concerns over patient growth postoperatively. This article presents ...
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