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Bacchetti T - - 2013
Background  Psoriasis is a chronic, inflammatory skin condition associated with a high frequency of cardiovascular events. Modifications of plasma lipids, and an increase in the levels of biochemical markers of inflammation and lipid peroxidation have been reported in subjects with psoriasis, suggesting a relationship between psoriasis, inflammation and oxidative damage. ...
Park Miyoung - - 2013
Exposure of the skin to ultraviolet (UV) irradiation induces photoageing through the up-regulation of matrix metalloproteinases (MMPs) and subsequent breakdown of extracellular matrices. Reactive oxygen species (ROS) and epidermal growth factor receptor (EGFR) activation play central roles in UV-induced MMP expression through initiating extracellular signal-regulated kinase (ERK)-mediated AP-1 signalling. We ...
Hartung Sheila Q - - 2013
: A qualitative design was used to decipher the viewpoints of nurse managers about communication trends associated with their leadership roles and unit subcultures. : Disruptive behaviors such as poor communication and inadequate teamwork have been associated with patient harm and deficient workplace cultures. However, few studies have focused on ...
Méndez Juan Pablo - - 2013
OBJECTIVE: Obesity and osteoporosis are two important public health problems that greatly impact mortality and morbidity. Several similarities between these complex diseases have been identified. The aim of this study was to analyze if different body mass indexes (BMIs) are associated with variations in bone mineral density (BMD) among postmenopausal ...
Arndt Sophia - - 2013
The formation of radicals plays an important role in the development of atopic eczema or barrier-disrupted skin. We evaluated the radical scavenging effect of a cream containing a Hypericum perforatum extract rich in hyperforin in a double-blind placebo-controlled study on 11 healthy volunteers. Electron paramagnetic resonance spectroscopy was applied to ...
Albouy Philippe - - 2013
Congenital amusia is a lifelong disorder of music perception and production. The present study investigated the cerebral bases of impaired pitch perception and memory in congenital amusia using behavioural measures, magnetoencephalography and voxel-based morphometry. Congenital amusics and matched control subjects performed two melodic tasks (a melodic contour task and an ...
Hickson Josiane - - 2013
: This study investigated the perceptions of nursing hostility and job satisfaction of new RNs, comparing the working settings of Magnet® and non-Magnet hospitals. : An online survey of new graduate RNs was conducted using the Negative Acts Questionnaire-Revised, the McCloskey/Mueller Satisfaction Survey, the Casey-Fink Graduate Nurse Experience Survey, and ...
Neubauer Hans - - 2013
Clinical trials have demonstrated an increased risk of breast cancer during estrogen/norethisterone (NET) therapy. With this in mind, the effects of estrogen/NET combination on the proliferation of breast cancer cells overexpressing the progesterone receptor membrane component 1 (PGRMC1) were examined. The same combination was used for the first time in ...
Santelli John S - - 2013
Adolescent risk-taking may have long-term consequences for adult cancer risk. Behaviors such as smoking and sexual activity, commonly initiated during adolescence, may result-decades later-in cancer. Life course epidemiology focuses on unique vulnerabilities at specific development periods and their importance to later development of disease. A life course epidemiological perspective that ...
Khosrotehrani Kiarash - - 2013
In recent years, few stem cells have gained as much clinical notoriety as mesenchymal stem cells. Indeed, MSCs are already in use for a range of systemic inflammatory and autoimmune conditions that also affect the skin, such as acute and chronic graft versus host disease or lupus erythematosus. Most interestingly, ...
Vucic Steve - - 2013
Riluzole, a benzothiazole derivative, has been shown to be effective in prolonging survival in amyotrophic lateral sclerosis. The mechanisms by which riluzole exerts neuroprotective effects in amyotrophic lateral sclerosis remains to be fully elucidated, although inhibition of glutamatergic transmission and modulation of Na(+) channel function have been proposed. In an ...
Henneman Elizabeth A - - 2013
: The objective of this study was to develop a reliable and valid checklist for documenting team and collaborative behaviors occurring during multidisciplinary bedside rounds. : Teamwork and collaboration are important for providing high-quality patient care, yet there are no objective means of evaluating the occurrence of team and collaborative ...
White Mary C - - 2013
Given the continued growth in the number of persons with cancer in the United States, the primary prevention of cancer remains an urgent public health priority. As the field of cancer prevention continues to mature and scientific knowledge evolves, it is imperative to challenge the status quo and embrace new ...
Lovely Mary Pat - - 2013
Purpose/Objectives: To explore the survivor experience of adults who have been diagnosed three years or longer with a primary malignant brain tumor (PMBT).Research Approach: Qualitative using a biographical narrative approach.Setting: Six sites across the United States.Participants: Survivors of PMBTs (N = 35) and their family caregivers (N = 35).Methodologic Approach: ...
Nguyen-Truong Connie K Y - - 2013
Purpose/Objectives: To identify factors associated with screening for colorectal cancer (CRC) and hepatitis B, because hepatitis B can increase the risk of liver cancer.Data Sources: MEDLINE®, CINAHL®, and PsycINFO databases from January 1998 to April 2012.Data Synthesis: The 23 reviewed studies included 15 descriptive, 2 intervention, 3 qualitative, 2 chart ...
Chilosi Anna Maria - - 2013
OBJECTIVE:: A growing number of studies on deaf children with cochlear implant (CI) document a significant improvement in receptive and expressive language skills after implantation, even if they show language delay when compared with normal-hearing peers. Data on language acquisition in CI Italian children are still scarce and limited to ...
Flaherty Anne Marie C - - 2013
Oncology Nursing Forum (ONF) published an article in its early newsletter format in 1977 entitled "Variables Affecting Nausea and Vomiting" (Mayer Scogna, 1977). That literature review provided an excellent analysis of the state of the art in the management of chemotherapy-induced nausea and vomiting (CINV) at that time. Healthcare providers ...
Wen Qiang - - 2013
The objective of this study was to evaluate the outcome and feasibility of concurrent chemotherapy with paclitaxel plus carboplatin and radiotherapy (RT) in patients with high-risk or advanced endometrial cancer. A retrospective analysis of patients treated between January 2003 and December 2009 was conducted. Adjuvant therapy consisted of external beam ...
Bay-Jensen Anne C - - 2013
Joint health is affected by local and systemic hormones. It is well accepted that systemic factors regulate the metabolism of joint tissues, and that substantial cross-talk between tissues actively contributes to homeostasis. In the current review, we try to define a subtype of osteoarthritis (OA), metabolic OA, which is dependent ...
Applegate Kimberly E - - 2013
Recently, the Cancer Prevention Across the Lifespan workgroup at the Centers for Disease Control held a workshop entitled "Identifying Opportunities for Cancer Prevention During Pre-Adolescence and Adolescence." With the goal of raising awareness and developing community and policy interventions to decrease risk factors for cancer, one session highlighted the danger ...
Christie Janice - - 2013
Editor's note: This is a summary of a nursing care-related systematic review from the Cochrane Library.
Wernicke A Gabriella - - 2013
Identification of radiation-induced fibrosis (RIF) remains a challenge with Late Effects of Normal Tissue-Subjective Objective Management Analytical (LENT-SOMA). Tissue compliance meter (TCM), a non-invasive applicator, may render a more reproducible tool for measuring RIF. In this study, we prospectively quantify RIF after intracavitary brachytherapy (IB) accelerated partial breast irradiation (APBI) ...
Wittersheim Maike - - 2013
Antimicrobial peptides (AMP) are key players in the skin's defense system. Previous observations suggest a site- and age-dependent expression of individual AMP. We investigated the expression and secretion patterns of four important AMP in a representative collective of healthy human skin samples. Levels of psoriasin, RNase 7 and hBD-3 expression ...
Stanic Sinisa - - 2013
The recently published Quantitative Analysis of Normal Tissue Effects in the Clinic (QUANTEC) recommends dose constraints for acute small-bowel toxicity but does not fully address dose constraints for late small-bowel toxicity and the maximum dose tolerance of the small bowel. Radiation oncologists in practice frequently face a challenge when deciding ...
Figueroa Arturo - - 2013
Postmenopausal women have increased arterial stiffness (brachial-ankle pulse wave velocity [baPWV]) and wave reflection. L-Citrulline supplementation reduces baPWV but not brachial blood pressure. Peripheral vasodilators decrease wave reflection amplitude or second systolic peak (SBP2) in radial artery and aorta, which are related to aortic systolic blood pressure (SBP). We examined ...
Morse Linda L - - 2013
Health, in its purest sense, is not the primary mission of the nation's K-12 schools, so why should schools feel obligated to address cancer education? The nation's educators are under tremendous pressure to prepare students to pass tests in English language arts and mathematics. As a result, health education and ...
Potera Carol - - 2013
Results in American Samoa could translate to other medically underserved areas.
Ginex Pamela - - 2013
Design: Longitudinal, descriptive study.Setting: An urban comprehensive cancer center in the northeastern United States.Sample: 218 patients with cancer of the esophagus undergoing esophagectomy.Methods: Symptoms were assessed by self-report before surgery, at the first postoperative visit, and at 6 and 12 months postsurgery.Main Research Variables: Symptoms and demographic and clinical variables, ...
Potera Carol - - 2013
There are no safe consumption levels, according to a new study.
Yang Rong - - 2013
It has been revealed that osteocalcin is a regulator of energy metabolism. We investigated the relationship between serum osteocalcin levels and metabolic syndrome (MetS) in Chinese postmenopausal women. A total of 1,789 postmenopausal women, aged 41 to 78 years, were selected from four communities in Shanghai, China. Serum levels of ...
Hussein Ha - - 2013
The validity of the body condition score (BCS) for evaluating subcutaneous fat has been questioned because of its subjectivity. With the advent of ultrasonography, backfat thickness (BFT) can be objectively measured and used to assess the energy status of dairy cows in conjunction with BCS. Determine the relationship between BCS ...
Rinnerthaler Mark - - 2013
The main function of the epidermis is to protect us against a multitude of hostile attacks from the environment. Its main cell type, the keratinocytes have a sophisticated system of different proteins and lipids available to form the cornified envelope, which is responsible for the barrier function of the skin. ...
Hill Karen S - - 2013
This interview, conducted by the editor, is the 1st in a series of interviews of emerging nurse scientists highlighting the department author, Jeffrey M. Adams, PhD, RN, director of the Center for Innovations in Care Delivery and Connell Nursing Research Scholar at Massachusetts General Hospital.
Collins Amy M - - 2013
A nurse-managed health care network offers 'one-stop shopping' for low-income patients.As part of its Raise the Voice campaign to showcase nurses who are key players in transforming health care, the American Academy of Nursing has identified nurses they call edge runners-"practical innovators who have led the way in bringing new ...
McCarthy James T - - 2013
Ozone is a tropospheric pollutant that can form at ground level as a result of an interaction between sunlight and hydrocarbon engine emissions. As ozone is an extremely oxidative reaction product, epidermal cells are in the outer layer of defense against ozone. We exposed normal human epidermal keratinocytes (NHEK) to ...
Morales-Campos Daisy Y - - 2013
Cervical cancer incidence and mortality are higher for Hispanic women than for women in other population groups. However, the incidence could be reduced if teenaged Hispanic girls received the human papillomavirus (HPV) vaccine before they become sexually active. Unfortunately, few Hispanic girls receive this vaccine, which prevents cervical cancer. This ...
McMillan Susan C - - 2013
Purpose/Objectives: To determine the severity and trajectory of constipation among patients with cancer from opioids and/or vinca alkaloids.Design: Exploratory, descriptive.Setting: Moffitt Cancer Center, a National Cancer Institute-designated comprehensive cancer center in Tampa, FL.Sample: 400 patients at risk for developing medication-induced constipation from opioids, vinca alkaloids, or both.Methods: Patients' baseline data ...
Cheng Guojun - - 2013
The aim of this study was to evaluate among postmenopausal women the effects of a 3-month treatment with estradiol (E2) alone or in combination with norethindrone acetate (NA) on expression of hormone receptors and proliferation in the breast as well as on lipids and climacteric symptoms. Sixty healthy postmenopausal women ...
Cagan Ross L - - 2013
To better translate basic research findings into the clinic, we are moving away from the traditional one-gene-one-phenotype model towards the discovery of complex mechanisms. In this Editorial, the new Editor-in-Chief and Senior Editors of Disease Models & Mechanisms (DMM) discuss the role that the journal will play in this transition. ...
Melnik Bodo C - - 2013
Acne in adolescents of developed countries is an epidemic skin disease and has currently been linked to the Western diet (WD). It is the intention of this viewpoint to discuss the possible impact of WD-mediated nutrient signalling in the pathogenesis of acne. High glycaemic load and dairy protein consumption both ...
Rescigno Maria - - 2013
The outcome of the interaction between plasmacytoid dendritic cells (pDCs) and bacteria has been very controversial: pDCs have been reported not to be activated by extracellular bacteria, to be activated but to only produce TNF-α and IL-6, or to be activated and produce IFN-α, the hallmark of pDC activation, but ...
Ono Yuko Y Department of Geriatric and Environmental Dermatology, Nagoya City University Graduate School of Medical Sciences, Mizuho-ku, Nagoya, - - 2013
Findings from large epidemiologic studies indicate that there is a link between smoking and extrinsic skin ageing. We previously reported that matrix metalloproteinases (MMPs) mediate connective tissue damage in skin exposed to tobacco smoke extracts. Tobacco smoke contains more than 3800 constituents, including numerous water-insoluble polycyclic aromatic hydrocarbons (PAHs) that ...
Yeom Hyun-E HE Department of Nursing in the College of Medicine, Dongguk University, Gyeongbuk, South Korea. - - 2013
To describe relationships among perceived barriers to symptom management and quality of life and to test the mediating role of perceived communication difficulties on the relationships between other perceived barriers to symptom management and quality of life in older adult breast cancer survivors. Cross-sectional descriptive-correlational design using baseline data from ...
Fein Miriam R MR Cold Spring Harbor Laboratory, 1 Bungtown Road, Cold Spring Harbor, NY 11724, - - 2013
The prognosis of metastatic cancer in patients is poor. Interfering with metastatic spread is therefore important for achieving better survival from cancer. Metastatic disease is established through a series of steps, including breaching of the basement membrane, intravasation and survival in lymphatic or blood vessels, extravasation, and growth at distant ...
Strunin Lee L Department of Community Health Sciences, Boston University School of Public Health, Boston, Massachusetts 02118-2605, USA. - - 2013
This article describes a feasibility study of a program that mentors boys aged 14-18 living in inner city public housing, engages them in a basketball league, and provides educational sessions on life skills and ways to resolve conflicts without violence. Such programs have the potential to engage adolescent males living ...
Newberry Alyssa G AG School of Nursing, University of Pittsburgh, Pennsylvania, USA. - - 2013
To determine whether the perceived level of spirituality in family caregivers of patients with primary malignant brain tumors (PMBTs) changes across the disease trajectory. Ongoing descriptive, longitudinal study. Southwestern Pennsylvania. 50 family caregivers of patients with PMBT. Caregivers and care recipients were recruited at time of diagnosis. Participants were interviewed ...
Kleszczynski Konrad K Department of Dermatology, University of Lübeck, Lübeck, - - 2013
Clinical disorders related to skin pigmentation include hypo- or hyperpigmentation. Because they are difficult to treat, new approaches to develop safe pigment modulatory agents are needed. In the March issue of the journal, Paterson et al. (Exp Dermatol, 22, 2013) determined which aldehyde dehydrogenase 1A1 (ALDH1A1) substrates and products regulate ...
Chamcheu Jean Christopher JC Department of Dermatology, School of Medicine and Public Health, University of Wisconsin, Madison, WI 53706, - - 2013
Delphinidin (Del), [3,5,7,3'-,4'-,5'-hexahydroxyflavylium], an anthocyanidin and a potent antioxidant abundantly found in pigmented fruits and vegetables exhibits proapoptotic effects in many cancer cells. Here, we determined the effect of Del on growth, apoptosis and differentiation of normal human epidermal keratinocytes (NHEKs) in vitro in submerged cultures and examined its effects ...
Weber Miriam T MT Department of Neurology, University of Rochester Medical Center, Rochester, NY 14642, USA. - - 2013
The aims of this cross-sectional study were to determine if cognitive function differs across stages of reproductive aging and to evaluate whether hormones or menopausal symptoms predict cognition in perimenopause. We hypothesized that women in late menopausal transition and early postmenopause would perform more poorly than those in the late ...
Bennett Jill A JA School of Nursing, Oregon Health and Science University, Portland, USA. - - 2013
To describe frailty and associated factors in breast cancer survivors (BCSs) and evaluate whether BCSs are frail at an earlier age than female participants from in two large epidemiological studies. Descriptive, cross-sectional. School of Nursing at Oregon Health and Science University. 216 BCSs aged 53-87 years who were a mean ...
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