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Applegate Kimberly E - - 2013
Recently, the Cancer Prevention Across the Lifespan workgroup at the Centers for Disease Control held a workshop entitled "Identifying Opportunities for Cancer Prevention During Pre-Adolescence and Adolescence." With the goal of raising awareness and developing community and policy interventions to decrease risk factors for cancer, one session highlighted the danger ...
Christie Janice - - 2013
Editor's note: This is a summary of a nursing care-related systematic review from the Cochrane Library.
Wernicke A Gabriella - - 2013
Identification of radiation-induced fibrosis (RIF) remains a challenge with Late Effects of Normal Tissue-Subjective Objective Management Analytical (LENT-SOMA). Tissue compliance meter (TCM), a non-invasive applicator, may render a more reproducible tool for measuring RIF. In this study, we prospectively quantify RIF after intracavitary brachytherapy (IB) accelerated partial breast irradiation (APBI) ...
Wittersheim Maike - - 2013
Antimicrobial peptides (AMP) are key players in the skin's defense system. Previous observations suggest a site- and age-dependent expression of individual AMP. We investigated the expression and secretion patterns of four important AMP in a representative collective of healthy human skin samples. Levels of psoriasin, RNase 7 and hBD-3 expression ...
Stanic Sinisa - - 2013
The recently published Quantitative Analysis of Normal Tissue Effects in the Clinic (QUANTEC) recommends dose constraints for acute small-bowel toxicity but does not fully address dose constraints for late small-bowel toxicity and the maximum dose tolerance of the small bowel. Radiation oncologists in practice frequently face a challenge when deciding ...
Figueroa Arturo - - 2013
Postmenopausal women have increased arterial stiffness (brachial-ankle pulse wave velocity [baPWV]) and wave reflection. L-Citrulline supplementation reduces baPWV but not brachial blood pressure. Peripheral vasodilators decrease wave reflection amplitude or second systolic peak (SBP2) in radial artery and aorta, which are related to aortic systolic blood pressure (SBP). We examined ...
Morse Linda L - - 2013
Health, in its purest sense, is not the primary mission of the nation's K-12 schools, so why should schools feel obligated to address cancer education? The nation's educators are under tremendous pressure to prepare students to pass tests in English language arts and mathematics. As a result, health education and ...
Bromberger Joyce T - - 2013
OBJECTIVE: Little is known about the risk of anxiety in women during midlife and the menopausal transition. We examined anxiety as a cluster of four symptoms and determined the association between menopausal stage and high anxiety during 10 years of follow-up of 2,956 women of multiple race/ethnicities. METHODS: This study ...
Potera Carol - - 2013
Results in American Samoa could translate to other medically underserved areas.
Ginex Pamela - - 2013
Design: Longitudinal, descriptive study.Setting: An urban comprehensive cancer center in the northeastern United States.Sample: 218 patients with cancer of the esophagus undergoing esophagectomy.Methods: Symptoms were assessed by self-report before surgery, at the first postoperative visit, and at 6 and 12 months postsurgery.Main Research Variables: Symptoms and demographic and clinical variables, ...
Potera Carol - - 2013
There are no safe consumption levels, according to a new study.
Yang Rong - - 2013
It has been revealed that osteocalcin is a regulator of energy metabolism. We investigated the relationship between serum osteocalcin levels and metabolic syndrome (MetS) in Chinese postmenopausal women. A total of 1,789 postmenopausal women, aged 41 to 78 years, were selected from four communities in Shanghai, China. Serum levels of ...
Hussein Ha - - 2013
The validity of the body condition score (BCS) for evaluating subcutaneous fat has been questioned because of its subjectivity. With the advent of ultrasonography, backfat thickness (BFT) can be objectively measured and used to assess the energy status of dairy cows in conjunction with BCS. Determine the relationship between BCS ...
Rinnerthaler Mark - - 2013
The main function of the epidermis is to protect us against a multitude of hostile attacks from the environment. Its main cell type, the keratinocytes have a sophisticated system of different proteins and lipids available to form the cornified envelope, which is responsible for the barrier function of the skin. ...
Hill Karen S - - 2013
This interview, conducted by the editor, is the 1st in a series of interviews of emerging nurse scientists highlighting the department author, Jeffrey M. Adams, PhD, RN, director of the Center for Innovations in Care Delivery and Connell Nursing Research Scholar at Massachusetts General Hospital.
Collins Amy M - - 2013
A nurse-managed health care network offers 'one-stop shopping' for low-income patients.As part of its Raise the Voice campaign to showcase nurses who are key players in transforming health care, the American Academy of Nursing has identified nurses they call edge runners-"practical innovators who have led the way in bringing new ...
McCarthy James T - - 2013
Ozone is a tropospheric pollutant that can form at ground level as a result of an interaction between sunlight and hydrocarbon engine emissions. As ozone is an extremely oxidative reaction product, epidermal cells are in the outer layer of defense against ozone. We exposed normal human epidermal keratinocytes (NHEK) to ...
Morales-Campos Daisy Y - - 2013
Cervical cancer incidence and mortality are higher for Hispanic women than for women in other population groups. However, the incidence could be reduced if teenaged Hispanic girls received the human papillomavirus (HPV) vaccine before they become sexually active. Unfortunately, few Hispanic girls receive this vaccine, which prevents cervical cancer. This ...
McMillan Susan C - - 2013
Purpose/Objectives: To determine the severity and trajectory of constipation among patients with cancer from opioids and/or vinca alkaloids.Design: Exploratory, descriptive.Setting: Moffitt Cancer Center, a National Cancer Institute-designated comprehensive cancer center in Tampa, FL.Sample: 400 patients at risk for developing medication-induced constipation from opioids, vinca alkaloids, or both.Methods: Patients' baseline data ...
Cheng Guojun - - 2013
The aim of this study was to evaluate among postmenopausal women the effects of a 3-month treatment with estradiol (E2) alone or in combination with norethindrone acetate (NA) on expression of hormone receptors and proliferation in the breast as well as on lipids and climacteric symptoms. Sixty healthy postmenopausal women ...
Frazier A Lindsay - - 2013
It is well established that exposures during childhood and adolescence affect breast cancer risk much later in life. Recently, studies have begun to evaluate whether early life exposures might also impact the risk of developing benign breast disease (BBD). A diagnosis of proliferative BBD independent of other breast cancer risk ...
Cagan Ross L - - 2013
To better translate basic research findings into the clinic, we are moving away from the traditional one-gene-one-phenotype model towards the discovery of complex mechanisms. In this Editorial, the new Editor-in-Chief and Senior Editors of Disease Models & Mechanisms (DMM) discuss the role that the journal will play in this transition. ...
Melnik Bodo C - - 2013
Acne in adolescents of developed countries is an epidemic skin disease and has currently been linked to the Western diet (WD). It is the intention of this viewpoint to discuss the possible impact of WD-mediated nutrient signalling in the pathogenesis of acne. High glycaemic load and dairy protein consumption both ...
Rescigno Maria - - 2013
The outcome of the interaction between plasmacytoid dendritic cells (pDCs) and bacteria has been very controversial: pDCs have been reported not to be activated by extracellular bacteria, to be activated but to only produce TNF-α and IL-6, or to be activated and produce IFN-α, the hallmark of pDC activation, but ...
Lazovich DeAnn D Division of Epidemiology and Community Health, University of Minnesota, Minneapolis, Minnesota 55454, USA. - - 2013
Indoor tanning usually begins during adolescence, but few strategies exist to discourage adolescent use. We developed and tested a parent-teenager intervention to decrease indoor tanning use. Through focus groups, we identified key messages to enhance parent-teenager communication about indoor tanning, and then developed a pamphlet for parents and postcards for ...
Ono Yuko Y Department of Geriatric and Environmental Dermatology, Nagoya City University Graduate School of Medical Sciences, Mizuho-ku, Nagoya, - - 2013
Findings from large epidemiologic studies indicate that there is a link between smoking and extrinsic skin ageing. We previously reported that matrix metalloproteinases (MMPs) mediate connective tissue damage in skin exposed to tobacco smoke extracts. Tobacco smoke contains more than 3800 constituents, including numerous water-insoluble polycyclic aromatic hydrocarbons (PAHs) that ...
Yeom Hyun-E HE Department of Nursing in the College of Medicine, Dongguk University, Gyeongbuk, South Korea. - - 2013
To describe relationships among perceived barriers to symptom management and quality of life and to test the mediating role of perceived communication difficulties on the relationships between other perceived barriers to symptom management and quality of life in older adult breast cancer survivors. Cross-sectional descriptive-correlational design using baseline data from ...
Fein Miriam R MR Cold Spring Harbor Laboratory, 1 Bungtown Road, Cold Spring Harbor, NY 11724, - - 2013
The prognosis of metastatic cancer in patients is poor. Interfering with metastatic spread is therefore important for achieving better survival from cancer. Metastatic disease is established through a series of steps, including breaching of the basement membrane, intravasation and survival in lymphatic or blood vessels, extravasation, and growth at distant ...
Biro Frank M FM Department of Pediatrics, University of Cincinnati College of Medicine, Division of Adolescent Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio 45229, USA. - - 2013
Early life exposures during times of rapid growth and development are recognized increasingly to impact later life. Epidemiologic studies document an association between exposures at critical windows of susceptibility with outcomes as diverse as childhood and adult obesity, timing of menarche, and risk for hypertension or breast cancer. This article ...
Strunin Lee L Department of Community Health Sciences, Boston University School of Public Health, Boston, Massachusetts 02118-2605, USA. - - 2013
This article describes a feasibility study of a program that mentors boys aged 14-18 living in inner city public housing, engages them in a basketball league, and provides educational sessions on life skills and ways to resolve conflicts without violence. Such programs have the potential to engage adolescent males living ...
Chamcheu Jean Christopher JC Department of Dermatology, School of Medicine and Public Health, University of Wisconsin, Madison, WI 53706, - - 2013
Delphinidin (Del), [3,5,7,3'-,4'-,5'-hexahydroxyflavylium], an anthocyanidin and a potent antioxidant abundantly found in pigmented fruits and vegetables exhibits proapoptotic effects in many cancer cells. Here, we determined the effect of Del on growth, apoptosis and differentiation of normal human epidermal keratinocytes (NHEKs) in vitro in submerged cultures and examined its effects ...
Sophonsritsuk Areepan A Section on Comparative Medicine, Department of Pathology, Wake Forest School of Medicine, Winston-Salem, NC 27157-1040, - - 2013
The aim of this study was to determine the effects of estrogen therapy (ET) on carotid artery inflammation when initiated early and late relative to surgical menopause. Female cynomolgus macaques consuming atherogenic diets were ovariectomized and randomized to control or oral estradiol (E2; human equivalent dose of 1 mg/d micronized ...
Newberry Alyssa G AG School of Nursing, University of Pittsburgh, Pennsylvania, USA. - - 2013
To determine whether the perceived level of spirituality in family caregivers of patients with primary malignant brain tumors (PMBTs) changes across the disease trajectory. Ongoing descriptive, longitudinal study. Southwestern Pennsylvania. 50 family caregivers of patients with PMBT. Caregivers and care recipients were recruited at time of diagnosis. Participants were interviewed ...
Bennett Jill A JA School of Nursing, Oregon Health and Science University, Portland, USA. - - 2013
To describe frailty and associated factors in breast cancer survivors (BCSs) and evaluate whether BCSs are frail at an earlier age than female participants from in two large epidemiological studies. Descriptive, cross-sectional. School of Nursing at Oregon Health and Science University. 216 BCSs aged 53-87 years who were a mean ...
Walton David S - - 2013
PURPOSE:To describe a cohort of children with late-recognized primary congenital glaucoma (LRPCG), including age of presentation, age-related diagnostic signs, clinical abnormalities, and results of glaucoma surgery. METHODS:The medical records of 31 patients (49 eyes) with PCG recognized after 1 year of age were reviewed retrospectively. Patients were confirmed to have ...
Lorena Silvia Helena Tavares - - 2013
PURPOSE:To determine the incidence of congenital nasolacrimal duct obstruction (CNLDO) in premature and full-term children. METHODS:Medical records of 200 premature and 200 full-term children from July 2004 to November 2009 at the Peri-Peri Health Center were retrospectively reviewed. Fifty-three nasolacrimal ducts in 32 premature children (21 patients were bilateral) and ...
Rupert Amy E AE Department of Chemistry, University of Pittsburgh, Pittsburgh, PA 15260, United - - 2013
We demonstrate here a method that perfuses a small region of an organotypic hippocampal culture with a solution containing an enzyme substrate, a neuropeptide. Perfusate containing hydrolysis products is continually collected and subsequently analyzed for the products of the enzymatic degradation of the peptide substrate. The driving force for perfusion ...
Bui Thuyet D - - 2013
Coastal shrimp farming may lead to the contamination of sediments of surrounding estuarine and marine ecosystems as shrimp farm effluent often contains high levels of pollutants including a range of organic compounds (from uneaten feed, shrimp feces, and living and dead organisms) which can accumulate in the sediments of receiving ...
Kitko Lisa A - - 2013
Heart failure requires complex home management, which is typically performed by a spouse. Yet little is known about the actual "work" of caregiving in individuals with heart failure. The purpose of this study was to describe the types of work manifested in long-term spousal caregiving for older adults across the ...
Melillo Karen Devereaux - - 2013
Cognitive health, memory complaints, and cognitive impairment among older workers have begun to receive attention in the research, practice, education, and policy arenas. With the aging population of the United States continuing to increase, projections are that the number of workers 65 and older is also expected to increase. Concerns ...
Berneburg M - - 2013
Phototherapy represents one of the essential options in the treatment of skin diseases by dermatologists. The beginnings of phototherapy were based on empirical observations and only later the underlying molecular and cellular mechanisms of the different modalities of phototherapy were unravelled by scientific research. Due to these findings, some phototherapeutic ...
Choi Jeungok - - 2013
Current text-based discharge instructions are unsuitable for low-literate older adults who have difficulty following written action-based instructions. To address this issue, we developed discharge instructions for low-literate older adults after hip replacement surgery using pictographs (i.e., simple line drawings with stick 3 gures showing explicit care actions). The aim of ...
Srimaroeng Chutima - - 2013
Background/Aims: In humans and rodents, organic anion transporter 3 (Oat3) is highly expressed on the basolateral membrane of renal proximal tubules and mediates the secretion of exogenous and endogenous anions. Regulation of Oat3 expression and function has been observed in both expression system and intact renal epithelia. However, information on ...
Hippe Hans-Jörg - - 2013
Heterotrimeric G proteins are key regulators of signaling pathways in mammalian cells. Beyond G protein-coupled receptors, the amount and mutual ratio of specific G protein α, β, and γ subunits determine the G protein signaling. However, little is known about mechanisms that regulate the concentration and composition of G protein ...
- - 2013
Acrolein is an aquatic herbicide used in the western United States to prevent impaired water flow in irrigation canals. Despite its toxicity, few cases of acrolein-related illness have been reported in the literature. On August 15, 2012, an irrigation district notified the Washington State Department of Labor & Industries (L&I) ...
- - 2013
Pneumococcal conjugate vaccines (PCVs) are safe and effective for reducing illness and deaths caused by Streptococcus pneumoniae. Recommendations for PCV use from the World Health Organization (WHO) and funding from the GAVI Alliance have resulted in an increase in PCV introductions into national immunization programs, especially in lower-income countries. Additionally, ...
- - 2013
Tubersol, a product of Sanofi Pasteur Limited, is in short supply nationwide until at least the end of May 2013. Tubersol is one of two purified-protein derivative (PPD) tuberculin products licensed by the Food and Drug Administration (FDA). The manufacturer has notified CDC that 50-dose vials of Tubersol will remain ...
Schulz R - - 2013
INTRODUCTION: Mobile geriatric rehabilitation is an outpatient rehabilitative treatment in which a multidisciplinary team treats elderly patients at home. This kind of treatment has been performed in rare cases in Germany but there are no data available on the effectiveness in patients with severe cognitive and functional impairment. MATERIAL AND ...
Henke M O - - 2013
Dyspnea is one of the major clinical symptoms which patients report to general practitioners, internists, cardiologists and hospitals. In this review article we discuss the evidence of medical history, laboratory procedures and diagnostic investigations to approach patients with acute or chronic dyspnea and try to structure this complex symptom dyspnea ...
Doll Gayle M - - 2013
Older adults' sexuality and sexual expression are often overlooked in nursing home and residential care settings. Despite cultural beliefs that this population is asexual, sexual activity occurs frequently among residents in long-term care. This study, using written survey instrumentation, examines the scope of resident sexuality, staff reactions to sexual behavior, ...
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