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Results 701 - 750 of 2349
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Longo Valéria Moraes - - 2013
In this research, an experimental and theoretical study was conducted to design a photo-degradation mechanism of the amino acid tryptophan (Trp) in hair fibers. For the experimental research Caucasian hair fibers were exposed to several different solar radiation simulation periods. Then Trp and its photo-products (N- formylkynurenine and kynurenine) were ...
Steiner Stephen Alan - - 2013
Hierarchical carbon fibers (CFs) sheathed with radial arrays of carbon nanotubes (CNTs) are promising candidates for improving intra- and interlaminar properties of advanced fiber-reinforced composites (e.g., graphite/epoxy) as well as high-surface-area electrodes for battery and supercapacitor architectures. While CVD growth of CNTs on CFs has been previously shown to improve ...
Hirota Jeremy A - - 2013
Inflammasomes have emerged as playing key roles in inflammation and innate immunity. A growing body of evidence has suggested that the nucleotide-binding domain and leucine-rich repeat protein 3 (NLRP3) inflammasome is important in chronic airway diseases such as asthma and COPD. Inflammasome activation results, in part, in pro-IL-1β processing and ...
Nekolaichuk Cheryl L - - 2013
Abstract Background: Standardized approaches for assessing and classifying cancer pain are required to improve treatment of patients with complex pain profiles. The Edmonton Classification System for Cancer Pain (ECS-CP) offers a starting point for the evolution of a standardized international classification system for cancer pain and was introduced into multisite ...
Yi Eui-Yeun - - 2013
Angiogenesis is an important process involved in tumor growth and metastasis. Many studies have investigated the use of natural compounds such as angiogenic inhibitors. Xylitol is a 5-carbon sugar alcohol and is an artificial sweetener that has been used in chewing gums to prevent tooth decay. Xylitol has been also ...
Kalkatawi Manal - - 2013
CONTACT: vladimir.bajic@kaust.edu.sa SUPPLEMENTARY INFORMATION: Supplementary data are available at Bioinformatics online.
Panarese Joseph D - - 2013
An efficient iodine-mediated oxidation of tetrahydro-β-carbolines is described to yield aromatic β-carboline products with tandem C-H oxidation. The utility of the method was demonstrated in total syntheses of the alkaloids eudistomins Y1-Y7.
Zhang Jing - - 2013
T-helper cells that produce IL-17 (Th17 cells) are a subset of CD4(+) T-cells with pathological roles in autoimmune diseases including systemic lupus erythematosus (SLE), and ETS1 is a negative regulator of Th17 cell differentiation. Our previous work on genome-wide association study (GWAS) identified two variants in the ETS1 gene (rs10893872 ...
Nimako Kofi - - 2013
We examined the accuracy and acceptability of a home telemonitoring system for patients receiving chemotherapy. Patients undergoing two cycles of chemotherapy (over six weeks) used the telemonitoring system to analyse their own blood (capillary) and to enter symptom and temperature data. The blood results obtained from self-testing were compared with ...
Stockis Armel - - 2013
PURPOSE: The aim of this study was to evaluate the effect of the antiepileptic drug lacosamide on the pharmacokinetics and pharmacodynamics of the anticoagulant warfarin. METHODS: In this open-label, two-treatment crossover study, 16 healthy adult male volunteers were randomized to receive a single 25-mg dose of warfarin alone in one ...
Holman Andrei - - 2013
The theory of emotional intensity (Brehm, 1999) suggests that the intensity of affective states depends on the magnitude of their current deterrents. Our study investigated the role that fluency-the subjective experience of ease of information processing-plays in the emotional intensity modulations as reactions to deterrents. Following an induction phase of ...
Roldán Elena Moreno - - 2013
Abstract Viruses are the leading cause of foodborne illness associated with the consumption of raw or slightly cooked contaminated shellfish. The aim of this study was to evaluate the prevalence of hepatitis A virus in molluscs. Standard and real-time reverse transcription-polymerase chain reaction procedures were used to monitor bivalve molluscs ...
Walsh Michael - - 2013
Patients with antineutrophil cytoplasm antibody-associated vasculitis (AAV) requiring dialysis at diagnosis are at risk for developing end-stage renal disease (ESRD) or dying. Short-term results of a trial comparing plasma exchange (PLEX) to intravenous methylprednisolone (IV MeP) suggested PLEX improved renal recovery. Here we conducted long-term follow-up to see if this ...
Wang Mei - - 2013
Colonization of the intestinal microbiota after birth plays an important role in development of the neonatal gastrointestinal and immune systems. Two key environmental factors that influence the colonization pattern are delivery mode and nutrition. In this study, the impact of delivery mode and nutrition on microbial colonization and metabolic activity ...
Pastor Jose M - - 2013
Bacterial osmoadaptation involves the cytoplasmic accumulation of compatible solutes in order to counteract extracellular osmolarity. The halophilic and highly halotolerant bacterium Chromohalobacter salexigens is able to grow up to 3 M NaCl in a minimal medium due to the de novo synthesis of ectoines. This is an osmoregulated pathway that ...
Migraine Audrey - - 2013
BACKGROUND: Preterm infants frequently present eating difficulties in early childhood. Determinants of these difficulties are not known. OBJECTIVE: We assessed the influence of neonatal and maternal characteristics on eating behaviors at 2 y of age. DESIGN: The following 2 cohorts were compared: 234 preterm children born <33 wk of gestational ...
Bliuc Dana - - 2013
CONTEXT: Following fracture there is increased risk of re-fracture and premature mortality. These outcomes, particularly premature mortality following re-fracture, have not previously been studied together to understand overall mortality risk. OBJECTIVES: This study examined the long-term cumulative incidence of subsequent fracture and total mortality with mortality calculated as a compound ...
Worasith Niramon - - 2013
Electron paramagnetic resonance (EPR) investigations of hair samples from various male and female subjects of different ages and races have revealed considerable variability in their Cu(II) signals. These signals seem to be a combination of two components whose relative proportions differ widely, although both have the relationship g// > g⊥ ...
Raz Gal - - 2013
Two empathy-related processes were recently distinguished neuroscientifically: automatic embodied-simulation (ES) based on visceromotor representation of another's affective state via cingulo-insulary circuit, and emotional sharing relying on cognitive "theory of mind" (ToM) via prefrontal-temporo-parietal circuit. Evidence that these regions are not only activated but also function as networks during empathic experience ...
Kullmann Lars - - 2013
For prey capture in the dark, the barn owl Tyto alba has evolved into an auditory specialist with an exquisite capability of sound localization. Adaptations include asymmetrical ears, enlarged auditory processing centers, the utilization of minute interaural time differences, and phase locking along the entire hearing range up to 10 ...
Rantalainen Timo - - 2013
Context:Increased mechanical loading can promote the preferential differentiation of bone marrow mesenchymal stem cells to osteoblastogenesis, but it is not known whether long-term bone strength-enhancing exercise in humans can reduce marrow adiposity.Objective:Our objective was to examine whether bone marrow density (MaD), as an estimate of marrow adiposity 1) differs between ...
Pringle Jan - - 2013
Abstract Purpose: This study aimed to investigate and improve understanding of the experiences of patients and their carers during the first month at home following discharge from hospital, thereby enhancing appropriate care from a more informed perspective. Method: In-depth interviews and self-report diaries were used to capture data from 12 ...
Cornall Alyssa M - - 2013
Anal squamous cell carcinomas are predominantly associated with high-risk human papillomaviruses (HPV), particularly HPV 16, similar to cervical, vaginal and vulvar cancers. Although the presence of "low-risk" HPVs, in particular genotypes 6 and 11, have occasionally been reported in various HPV-related anogenital cancers, the overall distribution of these genotypes in ...
Berkefeld Henrike - - 2013
Large conductance Ca(2+)- and voltage-activated potassium channels (BKCa) shape neuronal excitability and signal transduction. This reflects the integrated influences of transmembrane voltage and intracellular calcium concentration ([Ca(2+)]i) that gate the channels. This dual gating has been mainly studied as voltage-triggered gating modulated by defined steady-state [Ca(2+)]i, a paradigm that does ...
Zhang Pei-Pei - - 2013
One new lignan (7S,8R,7'R,8'R)-7-(3,4-methylenedioxyphenyl)-8,8'-dimethyl-8'-hydroxyl-7'-methoxyl-7'-(3',4'-methylenedioxyphenyl)-tetrahydrofuran (1), one new sesquiterpene 2-hydroxy-11,12-dehydrocalamenene (2), one new natural product erythro-1-(3,4-dimethoxyphenyl)-4-(3,4-methylenedioxyphenyl)-2,3-dimethyl-butane (3), and two known lignans (+)-anwulignan(erythro-1-(4-hydroxy-3-methoxyphenyl)-4-(3,4-methylenedioxyphenyl)-2,3-dimethyl-butane) (4) and ( - )-zuonin-A (5) were isolated from the stems of Schisandra glaucescens Diels. Their structures were elucidated by spectroscopic methods. The cytotoxicity of compounds 1 and 2 was assayed.
Thorn Perez Carolina - - 2013
Substance P is endogenously released within the locomotor network of the adult lamprey, accelerates the burst frequency of fictive locomotion and reduces the reciprocal inhibition. Previous studies have shown that dopamine, 5-HT and GABA regulate calcium channels, which control neurotransmitter release, action potential duration and slow afterhyperpolarization. Here we examine ...
Schneider Gabriela - - 2013
We observed that sphingosine-1-phosphate (S1P) and ceramide-1-phosphate (C1P) strongly enhance in vitro motility and adhesion of human rhabdomyosarcoma (RMS) cells. This effect was observed at physiological concentrations of both bioactive lipids, which are present in biological fluids, and is much stronger than the effects observed in response to known RMS ...
Hackbart Katherine S - - 2013
Polycystic ovarian syndrome (PCOS) is characterized by hyperandrogenemia, polycystic ovaries, and menstrual disturbance and a clear association with insulin resistance. This research evaluated whether induction of insulin resistance, using Dexamethasone (DEX), in a monovular animal model, the cow, could produce an ovarian phenotype similar to PCOS. In all of these ...
Chao Ying - - 2013
Scavenger receptors (SRs) are molecular pattern recognition receptors that have been shown to mediate opsonin-independent uptake of therapeutic and imaging nanoparticles, underlying the importance of SRs in nanomedicine. Unlike pathogens, engineered nanomaterials offer great flexibility in control of surface properties, allowing addressing specific questions regarding the molecular mechanisms of nanoparticle ...
Chaudhry Nauman S - - 2013
Over the last quarter century there has been significant progress toward identifying certain characteristics and patterns in GBM patients to predict survival times and outcomes. We sought to identify clinical predictors of survival in GBM patients from the past 24 years. We examined patient survival related to tumor locations, surgical treatment, ...
Pelletier Guillaume - - 2013
Imidazo[1,5-a]azines are synthesized in moderate to excellent yields using a mild cyclodehydration/aromatization reaction triggered by the use of triflic anhydride (Tf2O) and 2-methoxypyridine (2-MeOPyr). Various substitution patterns and functional groups were found to be compatible under the optimized conditions. In addition, a 5-bromo-3-aryl derivative was also shown to be active ...
Chang Huilan - - 2013
Abstract In classical group testing, one is given a population [Formula: see text] and an unknown subset [Formula: see text] of positive items, and the goal is to determine D by testing subsets of [Formula: see text]. Threshold group testing is a generalization of classical group testing, where the outcome ...
Nardo Davide - - 2013
Previous studies on crossmodal spatial orienting typically used simple and stereotyped stimuli in the absence of any meaningful context. This study combined computational models, behavioural measures and functional magnetic resonance imaging to investigate audiovisual spatial interactions in naturalistic settings. We created short videos portraying everyday life situations that included a ...
Truscott Byron J - - 2013
A family of iridium(I)-hydroxides of the form [Ir(cod)(NHC)(OH)] (cod=1,5-cyclooctadiene, NHC=N-heterocyclic carbene) is reported. Single-crystal X-ray analyses and computational methods were used to explore the structural characteristics and steric properties of these new complexes. The model complex [Ir(cod)(IiPr)(OH)] (IiPr=1,3-(diisopropyl)imidazol-2-ylidene) undergoes reaction with a wide variety of substrates including boronic acids and ...
Olver T Dylan - - 2013
This study tested the hypothesis that acute hyperglycemia reduces sciatic nerve blood flow in Sprague-Dawley rats. Anaesthetized rats underwent cannulation of their right jugular vein (for anaesthetic/nutrient/drug infusion) and right carotid artery (for continuous blood pressure measurement via pressure transducer). The left sciatic nerve was exposed and nerve blood velocity ...
Pires Isabel - - 2013
To evaluate macular thickness in eyes with mild nonproliferative diabetic retinopathy (NPDR), patients with diabetes type 2, NPDR level 20 or 35, and without evidence of clinical macular edema underwent best-corrected visual acuity assessment, color fundus photography and Stratus optical coherence tomography. Mean center point thickness (CPT) and mean central ...
Nicol B - - 2013
In mammals, follistatin (FST) plays an important role in early ovarian differentiation, acting downstream of the Wnt pathway. In teleost fish, fst is implicated in folliculogenesis and oocyte maturation, and an early and specific expression during ovarian differentiation has been described in rainbow trout, Oncorhynchus mykiss. By in situ hybridization, ...
Haifeng Qiu - - 2013
PURPOSE: none EXPERIMENTAL DESIGN: none RESULTS: none CONCLUSIONS: none.
Crump Christina J - - 2013
γ-Secretase is an aspartyl intramembranal protease composed of presenilin, Nicastrin, Aph1 and Pen2 with 19 transmembrane domains. γ-Secretase cleaves the amyloid precursor proteins (APP) to release Aβ peptides that likely play a causative role in the pathogenesis of Alzheimer disease (AD). In addition, γ-secretase cleaves Notch and other type I ...
Twomey Michèle - - 2013
OBJECTIVE: To evaluate the construct of triage acuity as measured by the South African Triage Scale (SATS) against a set of reference vignettes. METHODS: A modified Delphi method was used to develop a set of reference vignettes. Delphi participants completed a 2-round consensus-building process, and independently assigned triage acuity ratings ...
Bucens Ingrid Kirsten - - 2013
AIM: The aim of this study was to undertake a retrospective review of admissions and discharges to the neonatal unit at the National Hospital Guido Valadares, Dili, in order to gain insight into the epidemiology of hospitalised neonates in East Timor, as the information cannot be obtained from the hospital ...
Liao Chia-Ding - - 2013
Mycotoxins in foods have long been recognized as a potential health hazard due to their toxic and carcinogenic properties. A simple and rapid method was developed to detect mycotoxins (aflatoxins, ochratoxins, fumonisins, trichothecenes and ergot alkaloids) in corn, rice, wheat, almond, peanut, and pistachio. Test portions of homogenized grains or ...
Heffernan Kevin S - - 2013
BACKGROUND: Time spent in sedentary pursuits such as sitting (SIT) is associated with an increased risk of cardiovascular disease independent of physical activity (PA). The purpose of this study was to examine the associations of PA and SIT with central hemodynamic burden in young adults. METHODS: Aortic pressure waveforms were ...
Huang Xiaoqing - - 2013
Reinventing the wheel: Bimetallic AuPd nanowheels, a freestanding form of 2D AuPd nanostructures, were synthesized in a one-pot process. The well-defined and tunable surface plasmon resonance displayed by these nanowheels was exploited in a unique catalytic process in which light energy was used to drive catalytic reactions, such as the ...
Vlachopoulos Charalambos - - 2013
Erectile dysfunction is common in the patient with cardiovascular disease. It is an important component of the quality of life and it also confers an independent risk for future cardiovascular events. The usual 3-year time period between the onset of erectile dysfunction symptoms and a cardiovascular event offers an opportunity ...
Wang De-Hui - - 2013
OBJECTIVES/HYPOTHESIS: To investigate how quickly an allergic rhinitis (AR) patients' symptoms will improve with sublingual immunotherapy (SLIT). STUDY DESIGN: Double-blind placebo study. METHODS: This is a multicenter, randomized, double-blind, placebo-controlled study of SLIT used to treat house dust mite-induced AR. A total of 120 AR patients, aged 4 to 60 ...
Kumar S Sudalai - - 2013
Cardiosulfa is a biologically active sulfonamide molecule that was recently shown to induce abnormal heart development in zebrafish embryos through activation of the aryl hydrocarbon receptor (AhR). The present report is a systematic study of solid-state forms of cardiosulfa and its biologically active analogues that belong to the N-(9-ethyl-9H-carbazol-3-yl)benzene sulfonamide ...
Niescierenko Michelle - - 2013
PURPOSE OF REVIEW: To review the advances in the assessment, treatment, and evaluation of care for pediatric dehydration. RECENT FINDINGS: Recent studies have added new information across the spectrum of care for dehydration. Advances in the assessment of dehydration allow more accurate clinical evaluation, but do not help predict the ...
Lovera Andrea - - 2013
Fano resonances in hybridized systems formed from the interaction of bright modes only are reported. Despite precedent works, we demonstrate theoretically and experimentally that Fano resonances can be obtained by destructive interference between two bright dipolar modes out of phase. A simple oscillator model is provided to predict and fit ...
da Cunha Miriã Corália - - 2013
Abstract This study evaluated patients' expectation before and satisfaction after full-arch fixed implant-prosthesis rehabilitation. Other variables which could influence patient satisfaction with this therapy were also evaluated. A sample of 28 patients assigned, through a visual analog scale (VAS), scores for their expectation before and satisfaction after therapy regarding chewing, ...
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