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Godier-Furnémont Amandine F G - - 2013
The cardioprotective effects of mesenchymal stem cells (MSCs) include reducing myocyte apoptosis, and this effect can be enhanced by preconditioning and encapsulation in a fibrin scaffold. This study aimed to test the hypothesis that apoptosis imaging can detect the cardioprotective effects of a conditioned MSC patch grafted in a rat ...
Portran D - - 2013
Microtubules (MTs) are dynamic cytoskeletal elements involved in numerous cellular processes. While they are highly rigid polymers with a persistence length of 1-8 mm, they may exhibit curved shape at a scale of few micrometers within cells depending on their biological functions. However, how MT flexural rigidity in cells is ...
Aleman Soo - - 2013
Background. The long-term effect of sustained virological response (SVR) to antiviral therapy on the risk to develop hepatocellular cancer (HCC), liver complications, liver-related deaths and overall death in hepatitis C (HCV) infected patients with liver cirrhosis is not fully known. Methods. These risks were evaluated during long-term follow-up in in 351 patients ...
Niu Lvye - - 2013
A highly effective drug carrier is constructed by coating folic acid-terminated poly(ethylene glycol) (PEG-FA) on single walled carbon nanotubes (SWNTs) in a facile non-covalent method. The anti-cancer drug, doxorubicin (DOX), is further loaded on the surface of SWNTs at a very high loading efficiency, 149.3 ± 4.1%. The drug system (DOX/PEG-FA/SWNTs) exhibits ...
Guo Wenhua - - 2013
A sol-gel cooperative assembly method was demonstrated for the fabrication of inverse opal films with an open surface. In this method, a sol-gel silicate precursor was cooperatively assembled into the interstitial spaces of microspheres at the same time when polystyrene colloidal templates formed in between of two desired substrates. Silica ...
Kojima Taisuke - - 2013
This paper analyzes the use of a dehydrating oil system to determine binodal curves of aqueous two phase system (ATPS). Aqueous droplets containing phase-forming polymers are dehydrated at the interface between two immiscible oils. The droplets shrink due to diffusion of water into the oil phase while constantly maintaining a ...
Van Maldergem Lionel - - 2013
Existence of a discrete new X-linked intellectual disability (XLID) syndrome due to KIAA2022 deficiency was questioned by disruption of KIAA2022 by an X-chromosome pericentric inversion in a XLID family we reported in 2004. Three additional families with likely pathogenic KIAA2022 mutations were discovered within the frame of systematic parallel sequencing ...
Neale Alice - - 2013
OBJECTIVES: Perinatal depression and anxiety are prevalent in migrant women. The main aims of this literature review were to understand the psychosocial determinants of depression and anxiety in migrant women antenatally and to explore common clinical presentations. In addition, we aimed to identify barriers and facilitating factors for help-seeking and ...
Chokkanathan Srinivasan - - 2013
Objectives: Using the theory of religious effects (Journal for the Scientific Study of Religion, 42, 17-30 ( 2003 )), the current study examined the relationship among religiosity, psychosocial resources (social support and mastery) and psychological distress. Method: Through face-to-face interviewing, data were collected from 321 randomly selected older adults in ...
Ouweneel Else - - 2013
In order to answer the question whether changes in students' self-efficacy levels co-vary with similar changes in engagement and performance, a field study and an experimental study were conducted among university students. In order to do this, we adopted a subgroup approach. We created "natural" (Study 1) and manipulated (Study ...
Myachykov Andriy - - 2013
TEST is a novel taxonomy of knowledge representations based on three distinct hierarchically organized representational features: Tropism, Embodiment, and Situatedness. Tropic representational features reflect constraints of the physical world on the agent's ability to form, reactivate, and enrich embodied (i.e., resulting from the agent's bodily constraints) conceptual representations embedded in ...
Grolmusz V K - - 2013
The endocannabinoid system contributes to the regulation of appetite, food intake and energy balance. Fatty acid amide hydrolase is responsible for degradating anandamide, a key messenger of the endocannabinoid system. C385A is a common, functionally active genetic polymorphism of the gene encoding fatty acid amide hydrolase and has been associated ...
Eiselt Anne-Kathrin - - 2013
Processing quantity information based on abstract principles is central to intelligent behavior. Neural correlates of quantitative rule selectivity have been identified previously in the prefrontal cortex (PFC). However, whether individual neurons represent rules applied to multiple magnitude types is unknown. We recorded from PFC neurons while monkeys switched between "greater ...
Huang Yang - - 2013
Bending manipulation and direct force measurements of ultrathin boron nitride nanotubes (BNNTs) were performed inside a transmission electron microscope. Our results demonstrate an obvious transition in mechanics of BNNTs when the external diameters of nanotubes are in the range of 10 nm or less. During in situ transmission electron microscopy ...
Luykx Jurjen J - - 2013
The glutamatergic neurotransmission system and the N-methyl-D-aspartate receptor (NMDAR) have been implicated in smoking and alcohol consumption behavior. Preclinical studies have demonstrated that nicotine and ethanol influence NMDAR functionality, which may play a role in tendencies to consume these substances. Nonetheless, little is known about concentrations of NMDAR coagonists in ...
Ozbay Ismail - - 2013
Baling technology is a preferred method for temporary storage of municipal solid waste (MSW) prior to final disposal. If incineration is intended for final disposal of the bales, the energy content of the baled MSW gains importance. In this study, nine cylindrical bales containing a mix of different waste materials ...
Mallamaci Francesca - - 2013
Long-term visit-to-visit blood pressure (BP) variability predicts a high risk for cardiovascular events in patients with essential hypertension. Whether long-term visit-to-visit BP variability holds the same predictive power in predialysis patients with chronic kidney disease (CKD) is unknown. Here we tested the relationship between long-term visit-to-visit office BP variability and ...
Sun Jie - - 2013
Vasohibin-2 was recently identified as an important pro-angiogenesis factor in solid tumor and intracellular localization of its variants is important for elucidating the downstream mechanism(s) of its effects. Currently there are no reported antibodies affordable for intracellular localization. The aim of this study was to generate and characterize polyclonal antibodies ...
Maurage Pierre - - 2013
A correlation observed between chocolate consumption and the number of Nobel laureates has recently led to the suggestion that consuming more chocolate would increase the number of laureates due to the beneficial effects of cocoa-flavanols on cognitive functioning. We demonstrate that this interpretation is disproved when other flavanol-rich nutriment consumption ...
Arvizo Rochelle R - - 2013
Using nanoparticles to understand and target disease mechanisms is a burgeoning field whose immense potential is dependent upon fully defining nanoparticle-target cell interactions, especially in terms of toxicity. In this regard, cancer cells are surprisingly resistant to toxic effects of positively charged gold nanoparticles (+AuNPs). Our investigations led to the ...
Romano Joseph - - 2013
Thirty years after its beginning, the HIV/AIDS epidemic is still raging around the world. According to UNAIDS, in 2011 alone 1.7M deaths were attributable to AIDS, and 2.5M people were newly infected by the virus. Despite the success in treating HIV-infected people with potent antiretroviral drugs, preventing HIV infection is ...
Kim Hyungki - - 2013
Direct growth of a single to a few layers of graphene on a germanium nanowire (Gr/Ge NW; see picture) was achieved by a metal-catalyst-free chemical vapor deposition (CVD) process. The Gr/Ge NW was used as anode in a lithium ion battery. This material has a specific capacity of 1059 mA h g(-1) ...
Quinto Francesca - - 2013
(236)U was analyzed in a minerotrophic peat from the last interglacial period and an ombrotrophic peat core representing the last 80 years of atmospheric deposition. The determination of (236)U at levels of 10(7) atoms/g was possible by using ultra-clean laboratory procedures and accelerator mass spectrometry. In the interglacial peat samples ...
Zeidan Fadel - - 2013
Anxiety is the cognitive state related to the inability to control emotional responses to perceived threats. Anxiety is inversely related to brain activity associated with the cognitive regulation of emotions. Mindfulness meditation has been found to regulate anxiety. However, the brain mechanisms involved in meditation-related anxiety relief are largely unknown. ...
Wang Fang - - 2013
Six new glycosides (1-6) have been isolated from the flower buds of Lonicera japonica. Their structures including the absolute configurations were determined by spectroscopic and chemical methods as ( - )-2-hydroxy-5-methoxybenzoic acid 2-O-β-d-(6-O-benzoyl)-glucopyranoside (1), ( - )-4-hydroxy-3,5-dimethoxybenzoic acid 4-O-β-d-(6-O-benzoyl)-glucopyranoside (2), ( - )-(E)-3,5-dimethoxyphenylpropenoic acid 4-O-β-d-(6-O-benzoyl)-glucopyranoside (3), ( - )-(7S,8R)-(4-hydroxyphenylglycerol 9-O-β-d-[6-O-(E)-4-hydroxy-3,5-dimethoxyphenylpropenoyl]-glucopyranoside (4), ( - )-(7S,8R)-(4-hydroxy-3-methoxyphenylglycerol 9-O-β-d-[6-O-(E)-4-hydroxy-3,5-dimethoxyphenylpropenoyl]-glucopyranoside (5), and ( - )-4-hydroxy-3-methoxyphenol β-d-{6-O-[4-O-(7S,8R)-(4-hydroxy-3-methoxyphenylglycerol-8-yl)-3-methoxybenzoyl]}-glucopyranoside (6), ...
Gower Barbara A - - 2013
Context:Animal studies indicate that osteocalcin (OC), particularly the undercarboxylated isoform (unOC), affects insulin sensitivity and secretion, but definitive data from humans are lacking.Objective:To determine if total OC and unOC are independently associated with insulin sensitivity and β-cell response in overweight/obese adults; whether glucose tolerance status affects these associations; and whether ...
Ruljancic Nedjeljka - - 2013
The pathophysiology and treatment of depression involves monoamine neurotransmitters and the magnesium (Mg)-modulated monoaminergic pathway. Serum and platelet Mg concentrations and platelet serotonin concentrations were measured in 79 depressed patients who had attempted suicide, and 101 patients without suicidal behaviour, according to the ICD-10 diagnoses F 33.2 and F32.2, with ...
Dionisio Sasha - - 2013
Seizures are a commonly encountered medical problem. Seizure protocols have been shown to be effective by avoiding inappropriate over- and under treatment, but are not presently utilized in many centres in Australia. We outline a stepwise approach to effective seizure management based on timely investigation and escalating treatment with an ...
Pino Paco - - 2013
Possessing a system that experimentally controls gene expression has been a Holy Grail in molecular malaria research. Several strategies to control gene expression at different levels have been developed; the controlled step can range from transcription initiation to post-translational modification and/or protein degradation. Strategies successfully developed in model organisms and ...
Intlekofer Karlie A - - 2013
We demonstrate that exercise enables hippocampal-dependent learning in conditions that are normally sub-threshold for encoding and memory formation, and depends on hippocampal induction of brain-derived neurotrophic factor (BDNF) as a key mechanism. Using a weak training paradigm in an object location memory (OLM) task, we show that sedentary mice are ...
Neukamm Sabine S - - 2013
IRS2 as intermediate docking platform transduces the insulin/IGF-1 (insulin like growth factor 1) signal to intracellular effector molecules that regulate glucose homeostasis, β-cell growth and survival. Previously, IRS2 has been identified as 14-3-3 interaction protein. 14-3-3 proteins can bind their target proteins via phosphorylated serine/threonine residues located within distinct motifs. ...
Sánchez-Tena Susana - - 2013
Epidemiological and experimental studies suggest that fiber and phenolic compounds might have a protective effect on the development of colon cancer in humans. Accordingly, we assessed the chemopreventive efficacy and associated mechanisms of action of a lyophilized red grape pomace containing proanthocyanidin-rich dietary fiber (Grape Antioxidant Dietary Fiber, GADF) on ...
Lower Karen M - - 2013
Whereas mutations causing monogenic disorders most frequently lie within the affected gene, sequence variation in complex disorders is more commonly found in non-coding regions. Furthermore, recent genome-wide studies have shown that common DNA sequence variants in non-coding regions are associated with "normal" variation in gene expression resulting in cell-specific and/or ...
Righetti Aurélie A - - 2013
BACKGROUND: Iron deficiency (ID) is a major cause of anemia, along with other nutritional, parasitic, and genetic factors. Accurate biomarkers are needed to estimate the relative contribution of ID to anemia. Soluble transferrin receptor (sTfR) is thought to be unaffected by inflammation. OBJECTIVES: The objectives were to determine the difference ...
Smith David W - - 2013
Arabidopsis thaliana gene At5g06450 encodes a putative DnaQ-like 3'-5' exonuclease domain-containing protein (AtDECP). The DnaQ-like 3'-5' exonuclease domain is often found as a proofreading domain of DNA polymerases. The overall structure of AtDECP adopts an RNase H fold that consists of a mixed β-sheet flanked by α-helices. Interestingly, AtDECP forms ...
Zhang T - - 2013
The present study investigated the genotoxic effects of flumorph in various organs (brain, liver, spleen, kidney and sperm) of mice. The DNA damage, measured as comet tail length (µm), was determined using the alkaline comet assay. The comet assay is a sensitive assay for the detection of genotoxicity caused by ...
Guo Wei - - 2013
The growth arrest DNA damage-inducible gene (GADD45) family, which is composed of GADD45A, GADD45B, and GADD45G, may play similar but not identical roles in tumorigenesis. Genetic changes associated with or responsible for their dysregulation are in general uncommon. The present study was to detect the role of GADD45 gene family ...
Zhang Zhongheng - - 2013
Background and Objective: Enteral feeding is vital in the critical care setting; however, the optimal route of enteral feeding (postpyloric vs gastric feeding) remains debated. We aimed to systematically review the current evidence to see whether postpyloric feeding could provide additional benefits to intensive care unit (ICU) patients. Method: Randomized ...
Niyomchon Supaporn - - 2013
Catalytic asymmetric allylation of lactone 1 with allyl boronates leads to functionalized cyclobutenes in high regio- and stereoselectivity.
Smarandache-Wellmann Carmen R - - 2013
We conducted a quantitative analysis of the different non-spiking interneurons in the local pattern-generating circuits of the crayfish swimmeret system. Within each local circuit, these interneurons control the firing of the power-stroke and return-stroke motor neurons that drive swimmeret movements. Fifty four of these interneurons were identified during physiological experiments ...
Moric-Janiszewska Ewa - - 2013
The opportunity to distinguish an accurate set of genes associated with multigenic diseases such as cardiomyopathies or cardiac arrhythmias was very limited before the genomic era. Numerous methods of measuring RNA abundance exist, including northern blotting, multiplex polymerase chain reaction (PCR), and quantitative real-time reverse transcriptase-PCR. However, these techniques might ...
Popov Aleksandra - - 2013
Abstract Allergic contact dermatitis (ACD) is a common skin inflammatory disease that develops in hosts sensitized with contact allergens. Elucidation of dose-response relationships represents one of the approaches in studying the type of ACD in humans/animal models, termed as contact hyper-sensitivity reaction (CHS). Such studies have demonstrated that the intensity ...
Nguyen Su - - 2013
Abstract Due-date assignment plays an important role in scheduling systems and strongly influences the delivery performance of job shops. Because of the stochastic and dynamic nature of job shops, the development of general due-date assignment models (DDAMs) is complicated. In this study, two genetic programming (GP) methods are proposed to ...
Bhavnani Sanjeev P - - 2013
BACKGROUND: Several meta-analyses of the implantable cardioverter-defibrillator (ICD) clinical trials have demonstrated that while men derived a mortality reduction with prophylactic ICD implantation, women did not. These trials also observed that women receive less appropriate ICD shock therapy compared to men. We aimed to investigate this "gender-paradox" among a heterogeneous ...
Saravanan Subramanian - - 2013
This study investigated the hypothesis that the voluntary feed intake in fish is regulated by diet-induced differences in oxygen use. Four diets were prepared with a similar digestible protein:digestible energy ratio (18 mg/kJ), but which differed in the composition of nonprotein energy source. This replacement of fat (F) by starch ...
Rahman M M - - 2013
A series of Pt catalysts supported on Al2 O3 that was doped with different amounts of CeO2 was developed, characterized, and tested in the aqueous-phase reforming (APR) of glycerol to H2 . Catalyst 3Pt/3CeAl, which bore 3 wt % Pt on a support that contained 3 wt % CeO2 , showed the highest carbon ...
Ye Fei - - 2013
Three's a crowd: Tri- and tetrasubstituted allyl allenes can be easily accessed by this Cu(I) -catalyzed three-component coupling reaction of N-tosylhydrazones, terminal alkynes, and allyl halides. The reaction proceeds through a mechanism involving copper carbene migratory insertion.
Lee Soon Bo - - 2013
We report the electrochemical grafting of amine-terminated dendrimers encapsulating nanoparticles onto indium tin oxide (ITO) surfaces.
Zhang Tao - - 2013
We report a novel route to prepare multiresponsive organogels through charge-driven assembly between a block ionomer and a diblock copolymer. The ionic complex aggregates to form spherical cores, which are connected by the middle block of the block ionomer to form gels. The organogels are responsive to acids, amines and ...
Longo Valéria Moraes - - 2013
In this research, an experimental and theoretical study was conducted to design a photo-degradation mechanism of the amino acid tryptophan (Trp) in hair fibers. For the experimental research Caucasian hair fibers were exposed to several different solar radiation simulation periods. Then Trp and its photo-products (N- formylkynurenine and kynurenine) were ...
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