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Shiraishi Masahiro - - 2013
Background: Serum N-terminal pro-brain natriuretic peptide (NTproBNP) is often elevated in patients with acute Kawasaki disease (KD), but the NTproBNP level in normal children is higher than in adults. Thus, characterization of the normal levels and cut-off values of NTproBNP according to age is warranted for proper diagnosis of acute KD ...
Inglis R Fredrik RF Department of Environmental Sciences, ETH Zürich, Zürich, Switzerland. - - 2013
Bacteria produce a wide arsenal of toxic compounds in order to kill competing species. Bacteriocins, protein-based toxins produced by nearly all bacteria, have generally been considered a ubiquitous anti-competitor strategy, used to kill competing bacterial strains. Some of these bacteriocins are encoded on plasmids, which also code for closely linked ...
Neely Lori A - - 2013
Candida spp. cause both local and disseminated infections in immunocompromised patients. Bloodstream infections of Candida spp., known as "candidemia," are associated with a high mortality rate (40%), which is mainly attributed to the long diagnostic time required by blood culture. We introduce a diagnostic platform based on T2 magnetic resonance ...
Koehl Annemarie - - 2013
We present an X-ray absorption spectroscopy study on Fe-doped SrTiO3 thin films grown by pulsed laser deposition. The Fe L2,3 edge spectra are recorded for doping concentrations from 0-5% after several annealing steps at moderate temperatures. The Fe valence state is determined by comparison with an ilmenite reference sample and ...
Zheng Jianhua J MOH Key Laboratory of Systems Biology of Pathogens, Institute of Pathogen Biology, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100176, - - 2013
Tuberculosis (TB) is an infectious bacterial disease that causes morbidity and mortality, especially in developing countries. Although its efficacy against TB has displayed a high degree of variability (0%-80%) in different trials, Mycobacterium bovis bacillus Calmette-Guérin (BCG) has been recognized as an important weapon for preventing TB worldwide for over ...
Yan Xiaoqing - - 2013
Ordered, extra-large mesopores with highly loaded gold nanoparticles (AuNPs) exhibits unique sintering- and coking-resistant properties in gas-phase, cyclohexanol selective aerobic oxidation.
Ma Xiaofeng - - 2013
Many sensory brain regions are characterized by extensive local network interactions. However, we know relatively little about the contribution of this microcircuitry to sensory coding. Detailed analyses of neuronal microcircuitry are usually performed in vitro, whereas sensory processing is typically studied by recording from individual neurons in vivo. The electrosensory ...
Sheridan William Stephen - - 2013
Decellularized arterial scaffolds have achieved success in advancing towards clinical use as vascular grafts. However, concerns remain regarding long term preservation and sterilisation of these scaffolds. Freeze-drying offers a means of overcoming these concerns. In this study, we investigated the effects of various freeze-drying protocols on decellularized porcine carotid arteries ...
Ross Alastair B - - 2013
Epidemiological studies consistently find that diets rich in whole-grain (WG) cereals lead to decreased risk of disease compared with refined grain (RG)-based diets. Aside from a greater amount of fiber and micronutrients, possible mechanisms for why WGs may be beneficial for health remain speculative. In an exploratory, randomized, researcher-blinded, crossover ...
Hu Ying - - 2013
The epithelial-mesenchymal transition (EMT) has been implicated in various patho- physiological processes, including cancer cell migration and distal metastasis. Reactive oxygen species (ROS) and insulin receptor substrate-1 (IRS-1) are important in cancer progression and the regulation of EMT. To explore the biological significance and regulatory mechanism of EMT, we determined ...
Lyon G Marshall GM Emory University School of Medicine, Atlanta, Georgia, USA. - - 2013
Twelve laboratories evaluated candidate material for an Aspergillus DNA calibrator. The DNA material was quantified using limiting-dilution analysis; the mean concentration was determined to be 1.73 × 10(10) units/ml. The calibrator can be used to standardize aspergillosis diagnostic assays which detect and/or quantify nucleic acid.
Li Ning - - 2013
Selective oxidation of benzylic amines to imines with atmospheric O2 is achieved in water on TiO2 under UV irradiation. The afforded imine could be easily separated and TiO2 can be recycled by filtration. To scale up, gram-scale imine products can be obtained.
Yan Dongpeng - - 2013
Multi-component organic nanocrystals that are comprised of two or more supramolecular building blocks can be used to extend the design and assembly scope of solid molecular materials. Herein, we report the use of ultrasonication to prepare halogen-bonded stilbene-based nano-cocrystals that exhibit different photoemission properties, including one- and two-phonon emission and ...
Manesse Mael - - 2013
In this paper we present the development of an optical tweezers platform capable of creating on-demand dynamic microbead arrays for the multiplexed detection of biomolecules. We demonstrate the use of time-shared optical tweezers to dynamically assemble arrays of sensing microspheres, while simultaneously recording fluorescence signals in real time. The detection ...
Schmidt Bernd - - 2013
4-Phenol diazonium salts undergo Pd-catalyzed Heck reactions with various styrenes to 4'-hydroxy stilbenes. In almost all cases higher yields and fewer side products were observed, compared to the analogous 4-methoxy benzene diazonium salts. In contrast, the reaction fails completely with 2- and 3-phenol diazonium salts. For these substitution patterns the ...
Bytchkov Aleksei - - 2013
In contrast to the well-established structure of glassy GeS2, consisting of corner- and edge-sharing GeS4/2 tetrahedra, the structural features of Ge-rich sulfide alloys remain essentially unknown. Two contrasting points of view: (1) a tetrahedral model, and (2) a distorted NaCl approach were neither confirmed nor excluded mostly because of missing ...
Gondos Adam - - 2013
Serious concern arose in the scientific literature about the state of and progress in cancer survival among adolescent and young adult patients (AYA) in the recent years. We provide an up-to-date international comparison of survival among AYA patients. Using population based cancer data from 11 German cancer registries and the ...
Lin Hsin - - 2013
We investigate the topological surface state properties at various surface cleaves in the topological insulator Bi2Se3, via first principles calculations and scanning tunneling microscopy/spectroscopy (STM/STS). While the typical surface termination occurs between two quintuple layers, we report the existence of a surface termination within a single quintuple layer where dangling ...
Barina Rachelle - - 2013
The doctrine of the mature minor began as an emergency exception to the rule of parental consent. Over time, the doctrine crept into cases that were non-emergent. In this essay, we show how the doctrine also developed in the context of the latter part of the 20th century, at the ...
Vislay Rebecca L - - 2013
Fragile X syndrome (FXS) is a debilitating neurodevelopmental disorder thought to arise from disrupted synaptic communication in several key brain regions, including the amygdala, a central processing center for information with emotional and social relevance. Recent studies reveal defects in both excitatory and inhibitory neurotransmission in mature amygdala circuits in ...
Greene Justin M JM Department of Pathology and Laboratory Medicine, University of Wisconsin-Madison, Madison, Wisconsin, - - 2013
The live attenuated simian immunodeficiency virus (SIV) SIVmac239Δnef is the most effective SIV/human immunodeficiency virus (HIV) vaccine in preclinical testing. An understanding of the mechanisms responsible for protection may provide important insights for the development of HIV vaccines. Leveraging the uniquely restricted genetic diversity of Mauritian cynomolgus macaques, we performed ...
Naar-King Sylvie - - 2013
Objective. To describe the asthma medication device skills of high-risk African American adolescents and associations between skills and other components of illness management. Methods. 170 African American adolescents, with at least one hospitalization or two emergency department visits in the last year, demonstrated how they use their asthma quick relief ...
Wagner S - - 2013
Bryophyte biomass and diversity in tropical moist forests decrease dramatically from higher altitudes towards the lowlands. High respiratory carbon losses at high temperatures may partly explain this pattern, if montane species are unable to acclimatise their metabolic rates to lowland temperatures. We transplanted ten bryophyte species from two altitudes (1200 ...
Godier-Furnémont Amandine F G - - 2013
The cardioprotective effects of mesenchymal stem cells (MSCs) include reducing myocyte apoptosis, and this effect can be enhanced by preconditioning and encapsulation in a fibrin scaffold. This study aimed to test the hypothesis that apoptosis imaging can detect the cardioprotective effects of a conditioned MSC patch grafted in a rat ...
Portran D - - 2013
Microtubules (MTs) are dynamic cytoskeletal elements involved in numerous cellular processes. While they are highly rigid polymers with a persistence length of 1-8 mm, they may exhibit curved shape at a scale of few micrometers within cells depending on their biological functions. However, how MT flexural rigidity in cells is ...
Aleman Soo - - 2013
Background. The long-term effect of sustained virological response (SVR) to antiviral therapy on the risk to develop hepatocellular cancer (HCC), liver complications, liver-related deaths and overall death in hepatitis C (HCV) infected patients with liver cirrhosis is not fully known. Methods. These risks were evaluated during long-term follow-up in in 351 patients ...
Niu Lvye - - 2013
A highly effective drug carrier is constructed by coating folic acid-terminated poly(ethylene glycol) (PEG-FA) on single walled carbon nanotubes (SWNTs) in a facile non-covalent method. The anti-cancer drug, doxorubicin (DOX), is further loaded on the surface of SWNTs at a very high loading efficiency, 149.3 ± 4.1%. The drug system (DOX/PEG-FA/SWNTs) exhibits ...
Guo Wenhua - - 2013
A sol-gel cooperative assembly method was demonstrated for the fabrication of inverse opal films with an open surface. In this method, a sol-gel silicate precursor was cooperatively assembled into the interstitial spaces of microspheres at the same time when polystyrene colloidal templates formed in between of two desired substrates. Silica ...
Kojima Taisuke - - 2013
This paper analyzes the use of a dehydrating oil system to determine binodal curves of aqueous two phase system (ATPS). Aqueous droplets containing phase-forming polymers are dehydrated at the interface between two immiscible oils. The droplets shrink due to diffusion of water into the oil phase while constantly maintaining a ...
Van Maldergem Lionel L Centre de Génétique Humaine, Université de Franche-Comté, 25000 Besançon, France. - - 2013
Existence of a discrete new X-linked intellectual disability (XLID) syndrome due to KIAA2022 deficiency was questioned by disruption of KIAA2022 by an X-chromosome pericentric inversion in a XLID family we reported in 2004. Three additional families with likely pathogenic KIAA2022 mutations were discovered within the frame of systematic parallel sequencing ...
Neale Alice - - 2013
OBJECTIVES: Perinatal depression and anxiety are prevalent in migrant women. The main aims of this literature review were to understand the psychosocial determinants of depression and anxiety in migrant women antenatally and to explore common clinical presentations. In addition, we aimed to identify barriers and facilitating factors for help-seeking and ...
Chokkanathan Srinivasan - - 2013
Objectives: Using the theory of religious effects (Journal for the Scientific Study of Religion, 42, 17-30 ( 2003 )), the current study examined the relationship among religiosity, psychosocial resources (social support and mastery) and psychological distress. Method: Through face-to-face interviewing, data were collected from 321 randomly selected older adults in ...
Ouweneel Else - - 2013
In order to answer the question whether changes in students' self-efficacy levels co-vary with similar changes in engagement and performance, a field study and an experimental study were conducted among university students. In order to do this, we adopted a subgroup approach. We created "natural" (Study 1) and manipulated (Study ...
Myachykov Andriy - - 2013
TEST is a novel taxonomy of knowledge representations based on three distinct hierarchically organized representational features: Tropism, Embodiment, and Situatedness. Tropic representational features reflect constraints of the physical world on the agent's ability to form, reactivate, and enrich embodied (i.e., resulting from the agent's bodily constraints) conceptual representations embedded in ...
Yeung Jennifer J AP-HP, Hôpital Bicêtre, - - 2013
We report a case of varicella-zoster virus (VZV) myelitis in a woman with relapsing-remitting multiple sclerosis (RRMS) receiving natalizumab, a humanized monoclonal antibody that induces an immunosuppression localized to the CNS.
Grolmusz V K - - 2013
The endocannabinoid system contributes to the regulation of appetite, food intake and energy balance. Fatty acid amide hydrolase is responsible for degradating anandamide, a key messenger of the endocannabinoid system. C385A is a common, functionally active genetic polymorphism of the gene encoding fatty acid amide hydrolase and has been associated ...
Geraedts Maartje C P MC Department of Anatomy and Neurobiology, Division of Endocrinology, Diabetes and Nutrition, University of Maryland School of Medicine, Baltimore, Maryland 21201, - - 2013
Taste stimuli that evoke different perceptual qualities (e.g., sweet, umami, bitter, sour, salty) are detected by dedicated subpopulations of taste bud cells that use distinct combinations of sensory receptors and transduction molecules. Here, we report that taste stimuli also elicit unique patterns of neuropeptide secretion from taste buds that are ...
Li X-X - - 2013
Pollen presentation theory (PPT) predicts that plant species typically pollinated by frequent and wasteful pollinators ought to be much more parsimonious and only gradually release pollen compared to plant species pollinated by infrequent pollinators that are efficient at delivering the pollen they remove. To test PPT, we compare the pollen ...
Crandall Shane R SR Department of Pharmacology, University of Illinois, Urbana, IL, - - 2013
In the visual thalamus, retinal afferents activate both local interneurons and excitatory thalamocortical relay neurons, leading to robust feedforward inhibition that regulates the transmission of sensory information from retina to neocortex. Peculiarly, this feedforward inhibitory pathway is dominated by presynaptic dendrites. Previous work has shown that the output of dendritic ...
Colledge Sarah L - - 2013
An 8-year-old castrated male hound mix was referred to the Purdue University Veterinary Teaching Hospital for severe lameness, pollakiuria, and dyschezia. On presentation, the dog was nonweight bearing on the right rear limb and the right carpus was diffusely swollen. Synovial fluid analysis from the right carpus revealed a population ...
Takahiro Tsujita - - 2013
Using α-amylase inhibition as a separation guide, polyphenolic compounds from almond (Prunus dulcis) seed skin were purified using ultrafiltration, and Sephadex LH-20 and ODS columns. The purified fraction specifically and strongly inhibited α-amylase; the IC50 value was 2.2 μg/mL for pig pancreatic α-amylase. The fraction contained about 62 % of ...
Sadhukhan Tumpa - - 2013
We have investigated the ground state spin of ten pairs of possible photochromic diradical isomers by quantum chemical methods. Dihydrogen pyrenes and dinitrile pyrenes have been chosen as spacers with radical centers attached at (1,7) and (1,8) locations. Oxo-verdazyl has served as radical center, and both C- and N- linkages ...
Choy Kyungcheol K Center for Alaska Native Health Research, Institute of Arctic Biology, University of Alaska Fairbanks, Fairbanks, AK, - - 2013
An objective dietary biomarker would help clarify the contribution of sugar-sweetened beverage (SSB) intake to obesity and chronic disease risk. Previous studies have proposed the carbon isotope ratio (δ(13)C) as a biomarker of SSB intake but found associations that were of modest size and confounded by other components of the ...
First Matthew R - - 2013
Vertical migrations of living organisms and settling of particle-attached organisms lead to uneven distributions of biota at different depths in the water column. In ballast tanks, heterogeneity could lead to different population estimates depending on the portion of the discharge sampled. For example, concentrations of organisms exceeding a discharge standard ...
Nethercott Cara C School of Chemistry and Molecular Biosciences and Australian Infectious Diseases Research Centre, The University of Queensland, Brisbane, QLD, - - 2013
Infective endocarditis (IE) is a life-threatening infection of the heart endothelium and valves. Staphylococcus aureus is a predominant cause of severe IE and is frequently associated with infections in health care settings and device-related infections. Multilocus sequence typing (MLST), spa typing, and virulence gene microarrays are frequently used to classify ...
Chen Ruihong - - 2013
Two types of 4f-3d thiostannates with general formula [Hen]2 [Ln(en)4 (CuSn3 S9 )]⋅0.5 en (Ln1; Ln=La, 1; Ce, 2) and [Hen]4 [Ln(en)4 ]2 [Cu6 Sn6 S20 ]⋅3 en (Ln2; Ln=Nd, 3; Gd, 4; Er, 5) were prepared by reactions of Ln2 O3 , Cu, Sn, and S in ethylenediamine (en) under solvothermal ...
Chakraborty Debrup - - 2013
Objective. Ethanolic extract of Gymnema sylvestre (GS) leaves is used as a potent antidiabetic drug in various systems of alternative medicine, including homeopathy. The present study was aimed at examining if GS also had anticancer potentials, and if it had, to elucidate its possible mechanism of action. METHODS: We initially ...
Kim Jiyu - - 2013
CH activation: The ruthenium-catalyzed direct sp(2) CH amidation of arenes by using sulfonyl azides as the amino source is presented. A wide range of substrates were readily amidated including arenes bearing weakly coordinating groups. Synthetic utility of the thus obtained products was demonstrated in the preparation of biologically active heterocycles.
Schwartz J R - - 2013
Dandruff is a chronic, relapsing scalp condition which negatively impacts the quality of life of sufferers. Regular use of anti-fungal shampoos represents a proven therapeutic strategy to improve the most common symptoms of flakes and itch. Two recent approaches for enhancing efficacy of anti-fungal shampoos are maximizing bio-availability of the ...
Zou Liang-Hua - - 2013
An efficient catalytic system for Sonogashira-Hagihara-type reactions displaying ligand acceleration in the copper-catalyzed formation of C(sp(2) )C(sp) bonds is described. The structure of the ligand plays a key role for the coupling efficiency. Various copper sources show excellent catalytic activity, even in sub-mol % quantities. A wide variety of substituents is ...
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