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Results 551 - 600 of 2366
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Aitasalo Kalle M J - - 2013
BACKGROUND: A novel, bioactive, fibre-reinforced composite implant is a solution to address the shortcomings in craniofacial bone reconstruction. A longitudinal, clinical investigation with a follow-up time of 4 years, was conducted. METHODS: A cranial bone reconstruction with the implant was performed to 12 patients. In these patients, the reasons for ...
Suzuki Kazuo - - 2013
An international meeting, The Asia Pacific Meeting of Vasculitis and ANCA Workshop 2012, was held on March 28-31, 2012 at Shinagawa, Tokyo, Japan. The meeting focused on vasculitis and anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis in the Asia-Pacific area. This was a high-profile event and attracted scientists and physicians from around ...
Boonmuang Pornwalai - - 2013
BACKGROUND: HMG-CoA reductase inhibitors [statins], a widely prescribed cholesterol-lowering therapy, are associated with muscle-related adverse events. While characteristics of such events are well documented in Western countries, little data exists for the Thai population. OBJECTIVE: The aim of this study was to determine the characteristics of patients, type and dosing ...
Zhang W W Section of Digestive Diseases, Department of Medicine, Yale University School of Medicine, New Haven, CT, - - 2013
The Ashkenazi Jewish population has a several-fold higher prevalence of Crohn's disease (CD) compared with non-Jewish European ancestry populations and has a unique genetic history. Haplotype association is critical to CD etiology in this population, most notably at NOD2, in which three causal, uncommon and conditionally independent NOD2 variants reside ...
Sakamoto Ryota - - 2013
The present work reports a tripodal scaffold for bis(terpyridine)-Fe(ii) oligomer wires on an Au(111) surface: the tripodal scaffold realised both orthogonality of the oligomer wires, and fast interfacial electron transfer through the oligomer wires.
Kang Gun Woo - - 2013
Kienböck's disease, which consists of osteonecrosis and collapse of the lunate bone, causes chronic pain and dysfunction of the wrist. Patients on hemodialysis are occasionally present with wrist pain, but Kienböck's disease is rarely reported in dialysis patients. This case study describes Kienböck's disease in a patient with end-stage renal ...
Ballanti Eleonora - - 2013
The complement system is a component of the innate immune system. Its main function was initially believed to be limited to the recognition and elimination of pathogens through direct killing or stimulation of phagocytosis. However, in recent years, the immunoregulatory functions of the complement system were demonstrated and it was ...
Jae Sae Young - - 2013
We tested the hypothesis that acute inflammation may cause arterial stiffening in older adults. We further explored if high cardiorespiratory fitness may partially prevent the unfavorable effect of arterial stiffening produced by acute systemic inflammation in older adults. Using a randomized double-blind sham placebo-controlled design, forty healthy older adults were ...
Kaur Baljinder - - 2013
Ferulic acid (FA) is widely used in foods, in beverages, and in various pharmaceutical industries as a precursor of vanillin. FA biotransformation can occur during the growth of lactic acid bacteria (LAB), and its conversion to other phenolic derivatives is observed by many scientists, where ferulic acid esterase (FAE) and ...
Climent M A - - 2013
Bone metastases are a common complication of advanced prostate cancer and while they are less common in non-prostate genitourinary (GU) malignances, they have been reported in up to 35 % of patients with advanced renal cell carcinoma and bladder cancer. Furthermore, they may occur in more than two-thirds of those patients ...
Teles Alves Inês - - 2013
The VCaP cell line is widely used in prostate cancer research as it is a unique model to study castrate resistant disease expressing high levels of the wild type androgen receptor and the TMPRSS2-ERG fusion transcript. Using next generation sequencing, we assembled the structural variations in VCaP genomic DNA and ...
Jarvis Melanie - - 2013
AIM: To study the impact on newborn behavioural states and accuracy of three infrared thermometers compared with digital axillary thermometer measurements in very low birth weight infants. METHODS: Single-centre prospective observational study. Preterm infants born <1500-g birth weight were eligible. Infants were observed for pre-measurement behaviour state using a five-point ...
Keating Peter - - 2013
Although the ferret has become an important model species for studying both fundamental and clinical aspects of spatial hearing, previous behavioral work has focused on studies of sound localization and spatial release from masking in the free field. This makes it difficult to tease apart the role played by different ...
Janicsák Henriett - - 2013
OBJECTIVES: A host of medical, socio-demographic, and psychological factors that affect bone marrow transplantation (BMT) patients' quality of life (QOL) has been identified but due to the methodological diversity of the studies, the findings have been contradictory. The aim of this study was to examine the influence of somatic status, ...
Ko Jin-A - - 2013
This study aimed to develop an economically viable enzyme for the optimal production of steviol (S) from stevioside (ST). Of 9 commercially available glycosidases tested, S-producing β-glucosidase (SPGase) was selected and purified 74-fold from Penicillium decumbens naringinase by a three-step column chromatography procedure. The 121-kDa protein was stable at pH 2.3-6.0 ...
Megra Bezawit - - 2013
HIV infection and HIV neurocognitive impairment are major global health problems. The prevalence of HIV associated neurocognitive disorders (HAND) is increasing as people with HIV are living longer due to the success of antiretroviral therapies. Our laboratory identified the soluble form of (sPrP(c)), the cellular non-pathogenic isoform of the prion ...
Zubkova Ekaterina - - 2013
Alpha-fetoprotein (AFP) for long was known as immunomodulator and tumor marker having multifaceted actions on the activity of normal and transformed cells. In present study, we have investigated the involvement of AFP in regulation of THP-1 cell line invasion and underlying mechanisms. Treatment with human recombinant AFP causes up-regulation of ...
Sideroudi Haris - - 2013
BACKGROUND: The aim was to assess the intra-session, inter-session and inter-observer repeatability of curvature and aberrometric measurements of Pentacam-derived posterior corneal surface in normal control (CG), keratoconic (KCG) and after corneal collagen cross-linked (CXLG) groups. METHODS: This was a prospective, clinic-based, observational study that was conducted at the Eye Institute ...
Chau Rosanna M W - - 2013
Abstract Purpose: To examine the risk of fall for people with diabetes compared with healthy control subjects. Correlation between tactile sensation and postural control was examined for subjects with diabetes. Methods: Subjects with type 2 diabetes were classified into two groups: (i) diabetes without neuropathy (n = 23) and (ii) diabetic peripheral ...
Nishimura Rintaro - - 2013
Background: The surgical indication for chronic thromboembolic pulmonary hypertension (CTEPH) has been modified due to recognition of peripheral type CTEPH and changes in surgical methods and skill. Bosentan and sildenafil are used as modern oral therapy (mod Tx) in patients with inoperable CTEPH, although it remains unknown whether they have positive ...
Mora Leticia - - 2013
A key global challenge for plant biotechnology is addressing food security, whereby provision must be made to feed 9 billion people with nutritional feedstuffs by 2050. To achieve this step-change in Agricultural production new crop varieties are required that are tolerant to environmental stresses imposed by climate change, have better ...
Erken Eren - - 2013
We present two PHO siblings having a novel homozygous truncating mutation in HPGD. The purpose of the study was to attempt medical treatment, and to find the HPGD mutation causing the disease, in a 22-year old Turkish male and his 23-year old sister afflicted with primary hypertrophic osteoarthropathy (PHO). In ...
Cheng Jie J Laboratory of Metabolism, Center for Cancer Research, National Cancer Institute, National Institutes of Health , Bethesda, MD , USA - - 2013
1. Cytochrome P450 2D6 (CYP2D6) is a pivotal enzyme responsible for a major drug oxidation polymorphism in human populations. Distribution of CYP2D6 in brain and its role in serotonin metabolism suggest that CYP2D6 may have a function in the central nervous system. 2. To establish an efficient and accurate platform ...
Cavazza A - - 2013
Transplantation of epithelia derived from keratinocyte stem cells transduced by retroviral vectors is a potential therapy for epidermolysis bullosa (EB), a family of inherited skin adhesion defects. The biosafety characteristics of retroviral vectors in keratinocytes are, however, poorly defined. We developed self-inactivating (SIN) vectors derived from the Moloney murine leukemia ...
Victor Jan - - 2013
BACKGROUND: Recently, patient-specific guides (PSGs) have been introduced, claiming a significant improvement in accuracy and reproducibility of component positioning in TKA. Despite intensive marketing by the manufacturers, this claim has not yet been confirmed in a controlled prospective trial. QUESTIONS/PURPOSES: We (1) compared three-planar component alignment and overall coronal mechanical ...
Singh Ramesh K - - 2013
Effect of indole acetic acid (IAA)-overproducing mutants of Burkholderia cepacia (RRE25), a member of β-subclass of Proteobacteria and naturally occurring rice endophyte, was observed on the growth of rice (Oryza sativa L.) plants grown under greenhouse conditions. Nine mutants were characterized for altered biosynthesis of IAA after nitrous acid mutagenesis. ...
Wang Xiao Yan - - 2013
OBJECTIVE: To evaluate the role of positron emission tomography/computer tomography with fluorine-18 fluorodeoxyglucose (18F-FDG-PET/CT) in detection of hepatocellular carcinoma (HCC) recurrence after hepatectomy or radiofrequency ablation (RFA), and to compare its efficacy with contrast enhanced ultrasound (CEUS). METHODS: From January 2009 to December 2009, 36 HCC patients were included in ...
Johansson Malin B - - 2013
The optical and electronic properties of nanocrystalline WO3 thin films prepared by reactive dc magnetron sputtering at different total pressures (Ptot) were studied by optical spectroscopy and density functional theory (DFT) calculations. Monoclinic films prepared at low Ptot show absorption in the near infrared due to polarons, which is attributed ...
Matsumoto Seiji - - 2013
OBJECTIVES: To investigate bladder function in a model of nonbacterial prostatitis (NBP) induced in castrated rats by 17β-estradiol injection. METHODS: Ten-month-old male Wistar rats were divided into two groups, sham and NBP (both N = 8). NBP was induced by castration followed by daily subcutaneous injection of 17β-estradiol for 30 days. On the ...
Sun L - - 2013
Dabigatran etexilate (DE) has recently been introduced for stroke prevention in atrial fibrillation, but management of acute ischaemic stroke during therapy with DE is a challenge. Thrombolysis is contraindicated because of a presumed increased risk of intracerebral haemorrhagic complications. We studied in different ischaemia models whether DE increases secondary haemorrhage ...
Liu Peng P Division of Pharmaceutical Technology, Faculty of Pharmacy, University of Helsinki, P.O. Box 56, 00014 Helsinki, - - 2013
Sink conditions used in dissolution tests lead to rapid dissolution rates for nanosuspensions, causing difficulties in discriminating dissolution profiles between different formulations. Here, non-sink conditions were studied for the dissolution testing of poorly water-soluble drug nanosuspensions. A mathematical model for polydispersed particles was established to clarify dissolution mechanisms. The dissolution ...
Li-Bo Dai - - 2013
A simple and sensitive analytical method based on ultraperformance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS) has been developed for determination of moclobemide in human brain cell monolayer as an in vitro model of blood-brain barrier. Brucine was employed as the internal standard. Moclobemide and internal standard were extracted from cell supernatant ...
Huang Chih-Kun - - 2013
Laparoscopic sleeve gastrectomy (LSG) has been accepted as stand-alone restrictive bariatric procedure; laparoscopic adjustable gastric banded plication (LAGBP) is an innovative technique combining gastric banding and plication of the stomach. This study aims to compare LAGBP with LSG in terms of percent excess weight loss (%EWL), resolution of comorbidities, and ...
Choi Seung Ho - - 2013
SnO2-CuO composite nanorods with a Janus structure were prepared by one-step flame spray pyrolysis. High-aspect-ratio SnO2 nanorods were positioned on one side of the spherical CuO powder. The mean length of the rod-shaped crystals decreased from 200 to 20 nm when the SnO2 content in the composite powders decreased from ...
Yao Aining - - 2013
Imidazolium-based Fe-containing ionic liquids (ILs) can directly dissolve UO2 in the presence of their corresponding imidazolium chlorides without additional oxidants. The dissolution process follows pseudo first-order kinetics initially. Raman spectroscopic studies indicate that FeCl4(2-) is the predominant reduction product after UO2 dissolution, and attenuated total reflection-Fourier transform infrared spectroscopy indicates ...
Dawar Pankaj - - 2013
INTRODUCTION: Extrapulmonary skeletal involvement of calvarium in tuberculosis is very uncommon and presentation in an infant has never been reported. It usually presents as a painless scalp swelling, often with a discharging sinus. DISCUSSION: We report here a case of extensive calvarial tuberculosis seen in an infant presenting as exophytic ...
Shcherbinin S - - 2013
We investigate the quantitative accuracy of the reconstruction of absolute (99m)Tc and (111)In activities from (99m)Tc/(111)In dual-isotope SPECT studies. The separate reconstruction of two images is achieved by applying Monte Carlo simulation-based corrections for self-scatter and cross-talk between energy windows. For method evaluation, a series of (99m)Tc/(111)In physical phantom experiments ...
Zietz Carmen - - 2013
Larger femoral heads lead to a decreased risk of total hip dislocation and an improved range of motion. However, the larger diameter is associated with increased wear rates. The low wear rates of crosslinked polyethylene opens up the possibility of using larger heads. The aim of this experimental study was ...
Yazer Mark - - 2013
The growing use of group AB plasma in the United States in recent years poses unique challenges to blood centers and transfusion services. Blood centers must collect sufficient plasma components from a limited pool of group AB donors while taking steps to improve transfusion safety that further restricts the available ...
Costanzo Luca - - 2013
AIMS: Fabry disease (FD) is a rare X-linked genetic disorder caused by the deficiency or absent activity of lysosomal α-galactosidase A. Cardiovascular remodelling is a hallmark of FD. The present study aimed to comprehensively evaluate the cardiac, vascular and microvascular status in a population of patients with genetic mutations for ...
Pirog Tetyana - - 2013
Intensification of the surfactant synthesis by Rhodococcus erythropolis IMV Ac-5017 on different substrates, including industrial waste, as well as the use of surfactant preparations for oil degradation were studied. It was established that the addition of fumarate (0.2 %) and citrate (0.1 %) into the medium with ethanol, n-hexadecane, or glycerol (1-2 %) ...
Shikako-Thomas Keiko - - 2013
Abstract Introduction: Quality of life (QoL) is an important outcome of health interventions for children and youth with cerebral palsy (CP). When planning interventions it is fundamental to understand what constitutes a good QoL, a subjective construct, and what factors are important to consider from both parents' and children's perspectives. ...
Kim Tae-Young - - 2013
Thin films of rare earth (RE)-doped BiFeO3 (where RE=Sm, Ho, Pr and Nd) were grown on LaAlO3 substrates by using the pulsed laser deposition technique. All the films show a single phase of rhombohedral structure with space group R3c. The saturated magnetization in the Ho- and Sm-doped films is much ...
Condrea E - - 2013
We report results on the effect of strain on the thermopower and electrical resistance of glass-coated individual Bi nanowires. Here, we show that there is a critical diameter of wires below which the contribution of holes to the charge transport in pure Bi nanowires is more significant than that of ...
Won Hoyoun - - 2013
Although the presence of uncovered struts may be associated with occurrence of stent thrombosis, the impact of uncovered struts detected routinely by optical coherence tomography (OCT) on subsequent long-term clinical outcomes remains unclear. The objective of this study was to determine the cut-off value of uncovered struts that predicted adverse ...
Rozza-de-Menezes Rafaela Elvira - - 2013
Background: Oral nerve sheath myxoma (NSM) is an uncommon benign neoplasm with Schwann-cell origin, which is frequently mistaken for neurothekeoma. We report a case of NSM on the buccal mucosa in a 42-year-old woman. This case is compared with previously reported cases and a systematic review is performed. Methods and ...
Yan Wansen - - 2013
Internet addiction (IA) is an emerging social and mental health issue among youths. Analysis of risk factors, as well as their interactions, is crucial for understanding the development of IA. This study investigated the relationship between recent stressful life events, personality traits, perceived family functioning and IA in 892 college ...
Lee Kyoung Ho - - 2013
The process of establishing high-producing cell lines for the manufacture of therapeutic proteins is usually both time-consuming and laborious due to the low probability of obtaining high-producing clones from a pool of transfected cells and slow cell growth under the strong selective pressure of screening to identify high-producing clones. We ...
Bilgic Basar - - 2013
Coeliac disease (CD) is an autoimmune disease of small intestine associated with sensitivity to gluten. The clinical manifestations are often of gastrointestinal nature, although the disease may be present asymptomatically as well. It is a chronic disease and in the absence of overt neurological involvement, extended gluten exposure may give ...
Wei L G - - 2013
OBJECTIVE: Gated myocardial perfusion imaging (G-MPI) is regularly performed using single-photon emission computed tomography. The objective of this study was to evaluate the clinical value of 99Tcm-methoxyisobutylisonitrile (MIBI) myocardial imaging in glycogen storage disease (GSD). METHODS: 99Tcm-MIBI G-MPI was performed in nine patients with clinically proven GSD. QGS quantitative software ...
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