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Results 501 - 550 of 2349
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Sideroudi Haris - - 2013
BACKGROUND: The aim was to assess the intra-session, inter-session and inter-observer repeatability of curvature and aberrometric measurements of Pentacam-derived posterior corneal surface in normal control (CG), keratoconic (KCG) and after corneal collagen cross-linked (CXLG) groups. METHODS: This was a prospective, clinic-based, observational study that was conducted at the Eye Institute ...
Chau Rosanna M W - - 2013
Abstract Purpose: To examine the risk of fall for people with diabetes compared with healthy control subjects. Correlation between tactile sensation and postural control was examined for subjects with diabetes. Methods: Subjects with type 2 diabetes were classified into two groups: (i) diabetes without neuropathy (n = 23) and (ii) diabetic peripheral ...
Nishimura Rintaro - - 2013
Background: The surgical indication for chronic thromboembolic pulmonary hypertension (CTEPH) has been modified due to recognition of peripheral type CTEPH and changes in surgical methods and skill. Bosentan and sildenafil are used as modern oral therapy (mod Tx) in patients with inoperable CTEPH, although it remains unknown whether they have positive ...
Ch'ng Jun-Hong - - 2013
Due to the widespread prevalence of resistant parasites, chloroquine (CQ) was removed from front-line antimalarial chemotherapy in the 1990s despite its initial promise of disease eradication. Since then, resistance-conferring mutations have been identified in transporters such as the PfCRT, that allow for the efflux of CQ from its primary site ...
Perneger Thomas V - - 2013
PURPOSE: We explored health differences between population groups who describe their health as excellent, very good, good, fair, or poor. METHODS: We used data from a population-based survey which included self-rated health (SRH) and three global measures of health: the SF36 general health score (computed from the 4 items other ...
Chen Ling - - 2013
Plate- and octahedron-like Pt/Bi5Nb3O15 heterostructures are controllably prepared by a hydrothermal treatment method combined with photodeposition in the presence of different surfactants, i.e., cetyltrimethylammonium bromide (CTAB) and polyvinylpyrrolidone (PVP). The composition, structure, morphology, optical absorption properties, and textural properties of as-prepared Pt/Bi5Nb3O15 are well-characterized, and their simulated sunlight and visible-light ...
Meyer-Ter-Vehn Tobias - - 2013
INTRODUCTION: To study the long-term course in patients with idiopathic macular telangiectasia and report the effect of anti VEGF and laser treatment. METHODS: A retrospective case series of 19 patients/38 eyes with symptomatic type 2 idiopathic macular telangiectasia was performed. Six eyes received intravitreal injections of bevacizumab (1-3 injections), four ...
Jones Amanda L - - 2013
Recently we proposed that Rhodococcus equi (Magnusson 1923) Goodfellow and Alderson 1977 be transferred to a novel genus, Prescottia, as Prescottia equi comb. nov. However, in accordance with Principle 2 and Rule 51b(4) of the Bacteriological Code (1990 Revision), the bacterial genus name Prescottia Jones et al. 2013 is deemed ...
Persson Anja Bondke - - 2013
Beauty, we may assume, has fascinated mankind from its earliest beginnings. As the Oxford Dictionary tells us, beauty is "a combination of qualities […] that pleases the aesthetic senses, especially the sight" (Oxford Dictionary, 2013). The Italian novelist-philosopher Umberto Eco explained the "History of Beauty" (Eco 2004) throughout the ages ...
Davids Matthew S - - 2013
ABSTRACT Despite recent advances in the treatment of chronic lymphocytic leukemia (CLL) with chemoimmunotherapy, many CLL patients are older or frail and cannot tolerate aggressive chemotherapy. Even those who can inevitably develop resistance due to factors such as deletion of pro-apoptotic factors like TP53 or the support of pro-survival signals ...
Hofmann Darija - - 2013
BACKGROUND: Service-user partnerships in research exist in mental health, but there have been few advances in other disciplines, apart from cancer. OBJECTIVES: To develop a patient-generated expectancy measure for new treatments in rheumatoid arthritis (RA), using a participatory method. METHOD: Stage 1: three repeated focus groups and two expert panels ...
Lee Sung Yong - - 2013
Despite the conventional treatments of radiation therapy and chemotherapy, the 5-year survival rates for patients with advanced-stage cervical cancers remain low. Cancer immunotherapy has emerged as an alternative, innovative therapy that may improve survival. Here, we utilize a preclinical HPV-16 E6/E7-expressing tumor model, TC-1, and employ the chemotherapeutic agent cisplatin ...
Tarquini F - - 2013
Several epidemiological studies showed that gestational diabetes mellitus is the most frequent metabolic disorder of pregnancy, the pathogenesis of which has yet to be completely clarified. The aim of this study was to investigate the presence and processing of caspase 3 (Casp3) and poly(ADP-ribose) polymerase 1 (PARP1) in cord blood ...
Pratt G - - 2013
Bendamustine is a unique bifunctional alkylating agent with promising activity in myeloma. Despite the increasing number of studies demonstrating its efficacy in both the upfront and relapse settings, including patients with renal insufficiency, the optimal use of bendamustine, in terms of dosage, schedule and combination with other agents, has yet ...
Venkatasubbu G Devanand - - 2013
Targeted drug delivery using nanocrystalline materials delivers the drug at the deseased site. This increases the efficacy of the drug in killing the cancer cells. Surface modifications were done to target the drug to a particular receptor on the cell surface. This paper reports synthesis of hydroxyapatite and titanium dioxide ...
Johansson Pär I - - 2013
BACKGROUND: Hemorrhage accounts for most preventable trauma deaths, but still the optimal strategy for hemostatic resuscitation remains debated. STUDY DESIGN AND METHODS: This was a prospective study of adult trauma patients admitted to a Level I trauma center. Demography, Injury Severity Score (ISS), transfusion therapy, and mortality were registered. Hemostatic ...
Sakamoto Ryota - - 2013
The present work reports a tripodal scaffold for bis(terpyridine)-Fe(ii) oligomer wires on an Au(111) surface: the tripodal scaffold realised both orthogonality of the oligomer wires, and fast interfacial electron transfer through the oligomer wires.
Kang Gun Woo - - 2013
Kienböck's disease, which consists of osteonecrosis and collapse of the lunate bone, causes chronic pain and dysfunction of the wrist. Patients on hemodialysis are occasionally present with wrist pain, but Kienböck's disease is rarely reported in dialysis patients. This case study describes Kienböck's disease in a patient with end-stage renal ...
Ballanti Eleonora - - 2013
The complement system is a component of the innate immune system. Its main function was initially believed to be limited to the recognition and elimination of pathogens through direct killing or stimulation of phagocytosis. However, in recent years, the immunoregulatory functions of the complement system were demonstrated and it was ...
Jae Sae Young - - 2013
We tested the hypothesis that acute inflammation may cause arterial stiffening in older adults. We further explored if high cardiorespiratory fitness may partially prevent the unfavorable effect of arterial stiffening produced by acute systemic inflammation in older adults. Using a randomized double-blind sham placebo-controlled design, forty healthy older adults were ...
Kaur Baljinder - - 2013
Ferulic acid (FA) is widely used in foods, in beverages, and in various pharmaceutical industries as a precursor of vanillin. FA biotransformation can occur during the growth of lactic acid bacteria (LAB), and its conversion to other phenolic derivatives is observed by many scientists, where ferulic acid esterase (FAE) and ...
Kubo Akiharu - - 2013
The stratum corneum (SC), the outermost barrier of mammalian bodies, consists of layers of cornified keratinocytes with intercellular spaces sealed with lipids. The insolubility of the SC has hampered in-depth analysis, and the SC has been considered a homogeneous barrier. Here, we applied time-of-flight secondary ion mass spectrometry to demonstrate ...
Mai Liqiang - - 2013
Lithium-ion batteries (LIBs) are receiving considerable attention as storage devices in the renewable and sustainable energy developments. However, facile fabrication of long-life and high-rate cathode materials for LIBs is required to facilitate practical application. Here we report a favourable way to synthesize a Li3V2(PO4)3/C nanosphere cathode with three-dimensional (3D) continuous ...
Stanstrup Jan - - 2013
In this paper, we describe data processing and metabolite identification approaches which lead to a rapid and semi-automated interpretation of metabolomics experiments. Data from metabolite fingerprinting using LC-ESI-Q-TOF/MS were processed with several open-source software packages, including XCMS and CAMERA to detect features and group features into compound spectra. Next, we ...
Diaz K M - - 2013
The purpose of this study was to investigate the association of visit-to-visit and 24-h blood pressure (BP) variability with markers of endothelial injury and vascular function. We recruited 72 African Americans who were non-diabetic, non-smoking and free of cardiovascular (CV) and renal disease. Office BP was measured at three visits ...
Sofokleous Panagiotis - - 2013
PURPOSE: To produce electrospun polymeric fibrous wound dressing patches that can release the antibiotic drug amoxicillin in a controlled manner. METHODS: Poly(D,L-lactide-co-glycolide) acid (PLGA) fibrous dressings with entrapped amoxicillin were produced by electrospinning. The morphology and successful entrapment of amoxicillin in the PLGA fibrous dressings were validated by scanning electron ...
van Kessel C S - - 2013
BACKGROUND: A systematic preoperative evaluation to determine the individual resection strategy in patients with colorectal liver metastases (CRLM) was assessed as to its clinical value. PATIENTS AND METHODS: From 2009 to 2011, 75 patients with CRLM who were scheduled for surgery were prospectively included and received an additional preoperative systematic ...
Gundersen Maria T - - 2013
The great importance of amide bonds in industrial synthesis has encouraged the search for efficient catalysts of amide bond formation. Microbial transglutaminase (MTG) is heavily utilized in crosslinking proteins in the food and textile industries, where the side chain of a glutamine reacts with the side chain of a lysine, ...
Fisher Karen R - - 2013
Abstract Purpose: China has more than five million children with disabilities. According to national statistics, most of them (63%) do not receive the health and therapy services they need, which threatens their lives, wellbeing and opportunities in adult life. Method: The article applies mixed methods (secondary data analysis and case ...
Perini Violeta da Rocha - - 2013
This study investigated for the first time the reproductive biology of Prochilodus lineatus in a system of rivers in southeastern Brasil, relating it to the role of tributary rivers in the reproductive success of this important commercial fish in the Upper Paraná River basin, where a cascade of hydroelectric dams ...
Ménoret Mathilde - - 2013
Action observation and execution share overlapping neural resonating mechanisms. In the present study, we sought to examine the effect of the activation of this system during concurrent movement observation and execution in a prehension task, when no a priori information about the requirements of grasping action was available. Although it ...
Lizakowski SÅ‚awomir - - 2013
INTRODUCTION Different methods of enhanced pharmacological renin angiotensin system blockade lead to stronger antiproteinuric effects, but may be concerned about potential side effects. The therapies involving direct renin inhibitor, aliskiren have been occasionally suspected to promote renal fibrosis via stimulating (pro)renin receptor due to increased levels of renin  OBJECTIVES To shed more ...
Yoo Choong-Shik - - 2013
Carbon dioxide exhibits a richness of high-pressure polymorphs with a great diversity in intermolecular interaction, chemical bonding, and crystal structures. It ranges from typical molecular solids to fully extended covalent solids with crystal structures similar to those of SiO2. These extended solids of carbon dioxide are fundamentally new materials exhibiting ...
Chan-Chan L H - - 2013
Polyurethanes are very often used in the cardiovascular field due to their tunable physicochemical properties and acceptable hemocompatibility although they suffer from poor endothelialization. With this in mind, we proposed the synthesis of a family of degradable segmented poly(urea)urethanes (SPUUs) using amino acids (L-arginine, glycine and L-aspartic acid) as chain ...
Münkel Ronja - - 2013
Microalgae are discussed as a potential renewable feedstock for biofuel production. The production of highly concentrated algae biomass with a high fatty acid content, accompanied by high productivity with the use of natural sunlight is therefore of great interest. In the current study an outdoor pilot plant with five 30 ...
Suthar Manish Kumar - - 2013
Among various tropical diseases, malaria is a major life-threatening disease caused by Plasmodium parasite. Plasmodium falciparum is responsible for the deadliest form of malaria, so-called cerebral malaria. Purine nucleoside phosphorylase from P. falciparum is a homohexamer containing single tryptophan residue per subunit that accepts inosine and guanosine but not adenosine ...
Bruun-Olsen Vigdis - - 2013
Abstract Purpose: To examine the immediate and long-term effects of a walking-skill program compared with usual physiotherapy on physical function, pain and perceived self-efficacy in patients after total knee arthroplasty (TKA). Method: A single blind randomized controlled trial design was applied. Fifty-seven patients with primary TKA, mean age of 69 ...
Strauss Eli D - - 2013
How are color preferences formed, and can they be changed by affective experiences with correspondingly colored objects? We examined these questions by testing whether affectively polarized experiences with images of colored objects would cause changes in color preferences. Such changes are implied by the ecological valence theory (EVT), which posits ...
Cohen Stephanie A - - 2013
Increasing demand for genetic services has resulted in the need to evaluate current service delivery models (SDMs) and consider approaches that improve access to and efficiency of genetic counseling (GC). This study aimed to describe SDMs currently used by the GC community. The NSGC membership was surveyed regarding the use ...
Lin Zhixiong - - 2013
BACKGROUND: We evaluated the relationship of HPV and EBV with race in endemic and non-endemic cohorts of patients with nasopharyngeal carcinoma (NPC), and with smoking status in the non-endemic cohort. METHODS: Tissue microarrays (TMA) were constructed using samples from 86 patients treated in southern China and 108 patients from Stanford. ...
Seo Young-Kwon - - 2013
The purpose of this study was to evaluate the biological response and gene expression of New Zealand White Rabbit anterior cruciate ligament (ACL) fibroblasts for different wave lengths of light-emitting diode (LED) irradiation. In other words, this study was undertaken to evaluate the effects of different wavelengths of LED irradiation ...
Allen David G - - 2013
The study by Hvid et al. (2013) brings together two themes in muscle research; needle biopsy of human muscle and attempts to understand the mechanism of fatigue. Muscle biopsy has been in use since at least the time of Duchenne (1868) but the modern approach was pioneered by Bergström (1962). It ...
Mora Leticia - - 2013
A key global challenge for plant biotechnology is addressing food security, whereby provision must be made to feed 9 billion people with nutritional feedstuffs by 2050. To achieve this step-change in Agricultural production new crop varieties are required that are tolerant to environmental stresses imposed by climate change, have better ...
Erken Eren - - 2013
We present two PHO siblings having a novel homozygous truncating mutation in HPGD. The purpose of the study was to attempt medical treatment, and to find the HPGD mutation causing the disease, in a 22-year old Turkish male and his 23-year old sister afflicted with primary hypertrophic osteoarthropathy (PHO). In ...
Cheng Jie - - 2013
Abstract 1. Cytochrome P450 2D6 (CYP2D6) is a pivotal enzyme responsible for a major drug oxidation polymorphism in human populations. Distribution of CYP2D6 in brain and its role in serotonin metabolism suggest that CYP2D6 may have a function in the central nervous system. 2. To establish an efficient and accurate ...
Cavazza A - - 2013
Transplantation of epithelia derived from keratinocyte stem cells transduced by retroviral vectors is a potential therapy for epidermolysis bullosa (EB), a family of inherited skin adhesion defects. The biosafety characteristics of retroviral vectors in keratinocytes are, however, poorly defined. We developed self-inactivating (SIN) vectors derived from the Moloney murine leukemia ...
Victor Jan - - 2013
BACKGROUND: Recently, patient-specific guides (PSGs) have been introduced, claiming a significant improvement in accuracy and reproducibility of component positioning in TKA. Despite intensive marketing by the manufacturers, this claim has not yet been confirmed in a controlled prospective trial. QUESTIONS/PURPOSES: We (1) compared three-planar component alignment and overall coronal mechanical ...
Singh Ramesh K - - 2013
Effect of indole acetic acid (IAA)-overproducing mutants of Burkholderia cepacia (RRE25), a member of β-subclass of Proteobacteria and naturally occurring rice endophyte, was observed on the growth of rice (Oryza sativa L.) plants grown under greenhouse conditions. Nine mutants were characterized for altered biosynthesis of IAA after nitrous acid mutagenesis. ...
Wang Xiao Yan - - 2013
OBJECTIVE: To evaluate the role of positron emission tomography/computer tomography with fluorine-18 fluorodeoxyglucose (18F-FDG-PET/CT) in detection of hepatocellular carcinoma (HCC) recurrence after hepatectomy or radiofrequency ablation (RFA), and to compare its efficacy with contrast enhanced ultrasound (CEUS). METHODS: From January 2009 to December 2009, 36 HCC patients were included in ...
Johansson Malin B - - 2013
The optical and electronic properties of nanocrystalline WO3 thin films prepared by reactive dc magnetron sputtering at different total pressures (Ptot) were studied by optical spectroscopy and density functional theory (DFT) calculations. Monoclinic films prepared at low Ptot show absorption in the near infrared due to polarons, which is attributed ...
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