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Moyer Kurtis E - - 2013
: Breast implant capsular contracture is a common complication of implant-based breast reconstruction. To develop nonsurgical interventions to combat breast capsular contractures, a clearer understanding of the process is required. Comparing breast implant-related capsular contracture to the fibrotic scarring process, the hypothesis is that these processes differ with regard to ...
George Betsy Ann - - 2013
Two men, one 63 and one 52 years old, presented with ascites. Analysis of the ascitic fluid in both patients revealed a high protein content and an elevated serum-ascites gradient. Various studies showed the cause of the ascites to be constrictive pericardial disease. Total excision of their parietal pericardia relieved ...
Su H - - 2013
Hyperactive ribosomal biogenesis is widely observed in cancer, which has been partly attributed to the increased rDNA transcription by Pol I in cancer. However, whether small nucleolar RNAs (snoRNAs), a class of non-coding RNAs crucial in ribosomal RNA (rRNA) maturation and functionality, are involved in cancer remains elusive. We report ...
Zhu Min - - 2013
: Successful long-term volume retention of an autologous fat graft is problematic. The presence of contaminating cells, tumescent fluid, and free lipid in the graft contributes to disparate outcomes. Better preparation methods for the fat graft before transplantation may significantly improve results. : Subcutaneous fat from 22 donors was divided ...
Ha Kelli Y - - 2013
Inflammatory breast carcinoma is a rare form of invasive breast cancer often characterized by erythema, warmth, and a classic "peau de orange" or "orange peel" appearance of the affected breast. The average age of onset is within the fourth and fifth decades. Lesions are usually detected and evaluated with mammography, ...
Montalbano Roberta - - 2013
Panobinostat, a pan-deacetylase inhibitor, represents a novel therapeutic option for cancer diseases. Besides its ability to block histone deacetylases (HDACs) by promoting histone hyperacetylation, panobinostat interferes with several cell death pathways providing a potential efficacy against tumors. We have previously demonstrated that panobinostat has a potent apoptotic activity in vitro ...
Concepción Ramírez L - - 2013
Rhipicephalus (Boophilus) microplus is a tick that causes huge economic losses in cattle. The indiscriminate use of acaricides has generated resistance to most compounds present on the market. This makes further investigation on other potential acaricides necessary, the in silico assay being an alternative to the design of new compounds. ...
Riedl Otto - - 2013
: The sural nerve is commonly used as donor for nerve grafting. Contrary to its constant retromalleolar position, formation and course of the proximal sural nerve show great variability. The coexistence of different and deceptive terminologies contributes to the complexity, and reviewing the international literature is confusing. Because detailed anatomical ...
Bello Shakirat I - - 2013
This study evaluated the quality of life (QoL) and associated factors for 160 HIV/AIDS patients in Sobi Specialist Hospital, Ilorin, Nigeria. The patients were assessed with the World Health Organization Quality of Life Questionnaire-Short Version. Frequency distribution, percentages, and means were employed for the statistical analysis of the results. The ...
Wertheim David - - 2013
The aim of this study was to investigate whether respiratory information can be derived from pulse oximetry plethysmogram (pleth) recordings in acutely wheezy preschool children. A digital pulse oximeter was connected via 'Bluetooth' to a notebook computer in order to acquire pleth data. Low pass filtering and frequency analysis were ...
Chen Li - - 2013
Objective: To assess zero drift of intraventricular and subdural intracranial pressure (ICP) monitoring systems. Methods: A prospective study was conducted in patients who received Codman ICP monitoring in the neurosurgical department from January 2010 to December 2011. According to the location of sensors, the patients were ca- tegorized into two ...
Webb Kevin - - 2013
Malignant biliary obstruction can arise from intrahepatic, extrahepatic, and hilar locations from either primary or metastatic disease. Biliary-enteric surgical bypass has been surpassed in the last 20 years by endoscopic balloon dilation and stenting. The goal of stenting for biliary decompression is to palliate obstructive symptoms; it has not been ...
Kijsirichareanchai Kunut - - 2013
To improve the adherence to AASLD (American Association for the Study of Liver Diseases) guidelines for variceal bleeding, we developed and implemented standardized order sets for gastrointestinal bleeding in our hospital on October 1, 2009. We performed medical record reviews of hospitalized patients with gastrointestinal bleeding with suspected cirrhosis from ...
Khurana Kamal K - - 2013
Abstract Objective: Rapid on-site evaluation (ROSE) at the time of endobronchial ultrasound-guided transbronchial fine needle aspiration (EBUS-TBFNA) is useful in obtaining adequate samples and providing preliminary diagnosis. We present our experience with ROSE of EBUS-TBFNA using telecytopathology. Materials and Methods: Real-time images of Diff-Quik (Mercedes Medical, Sarasota, FL)-stained cytology smears ...
Bury Marina - - 2013
Glioblastoma multiforme (GBM) is a deadly cancer that possesses an intrinsic resistance to pro-apoptotic insults, such as conventional chemotherapy and radiotherapy, and diffusely invades the brain parenchyma, which renders it elusive to total surgical resection. We found that fusicoccin A, a fungal metabolite from Fusicoccum amygdali, decreased the proliferation and ...
Nishihori T - - 2013
Allogeneic hematopoietic cell transplantation (HCT) is a potentially curative approach in patients with multiple myeloma, but its use for consolidation of first remission has not yet been fully explored. Twenty-two myeloma patients with very good partial response (VGPR) or CR received allogeneic peripheral blood grafts as consolidation from HLA-matched donors ...
Ducker G S - - 2013
The mammalian target of rapamycin (mTOR) regulates cell growth by integrating nutrient and growth factor signaling and is strongly implicated in cancer. But mTOR is not an oncogene, and which tumors will be resistant or sensitive to new adenosine triphosphate (ATP) competitive mTOR inhibitors now in clinical trials remains unknown. ...
Chaves Christianne Pereira Giesbrecht - - 2013
This study aimed to investigate the role of exercise order on total number of repetitions and to evaluate the possible importance on muscle damage and on rating perceived exertion (RPE). Ten trained participants completed two sequences: sequence A (SEQA) was leg press (LP), leg extension (LE), leg curl (LC), bench ...
Hermann Christopher D - - 2013
: Craniosynostosis is the premature fusion of cranial sutures early in development. Mice are commonly used to study the mechanisms driving both normal and pathologic cranial suture development. Despite their frequency of use as a model, the time course of bone formation and mineralization during fusion of mouse posterior frontal ...
Yang Xiaodong - - 2013
: There is a dearth of detailed published work on anterolateral leg perforators. The authors fully documented the vascular basis of the anterolateral leg perforator flap and report its use in reconstruction of distal extremities. : Anterolateral leg perforators were investigated in 25 fresh cadavers and 10 casts of arteries. ...
Chase Kristin I - - 2013
The purposes of this study were to determine the incidence and distribution of injuries affecting collegiate competitive swimmers and to test possible injury risk factors. A prospective cohort design was used to follow 34 swimmers (16M, 18F) from an NCAA Division I Midwest University over one academic year. Exposure-based injury ...
Saxsena Aneeta - - 2013
Since the introduction of recombinant tissue plasminogen activator and thrombolysis, acute ischemic stroke has become a treatable disorder if the patient presents within the 4.5-hour time window. Typically, sporadic stroke is caused by atherosclerotic disease involving large or small cerebral arteries or secondary to a cardioembolic source often associated with ...
Mishra S - - 2013
This study was focused to evaluate protection of indigenous antioxidant system of mice against gamma radiation-induced oxidative stress using a semiquinone (SQGD)-rich fraction isolated from Bacillus sp. INM-1. Male C57bl/6 mice were administered SQGD (50 mg/kgb.w.i.p.) 2 h before irradiation (10 Gy) and modulation in antioxidant enzymes activities was estimated at different time ...
Vandarakis Dimitria - - 2013
This study determined the reliability of measuring resting metabolic rate (RMR) with COSMED's FitMate™ metabolic system using a canopy dilution set-up compared with a previously validated COSMED QUARK CPET research-based system in 30 healthy adults (age: 28.4 ± 7.0 yrs, weight: 79.9 ± 20.2 kg, percent body fat: 22.5 ± ...
Devgan Ashish - - 2013
Nonunion in tibial plateau fractures is very rare. Limited literature is available on Pubmed search on intraarticular tibial nonunion. Most of the cases reported have been following failed surgical treatment and none was neglected fractures. Three patients of isolated and neglected medial tibial plateau nonunion with almost similar demographic profile ...
Baillie John - - 2013
Laparoscopic cholecystectomy (LC) is complicated by bile duct injury in 0.3% to 0.6% of cases. These injuries range from simple leaks from the cystic duct stump that can almost always be managed by endoscopic stenting to complex strictures, transections, and even resections of the bile duct, often with concomitant vascular ...
Katsuno Makoto - - 2013
<i>Background and Purpose</i>: In general, upper basilar artery aneurysms are treated following the transsylvian or subtemporal approach. These approaches have both advantages and disadvantages. Therefore, we followed the anterior temporal approach that provides a wider surgical field in the retro-carotid space. <i>Methods</i>: We reviewed the clinical records of 37 patients ...
Kao Huang-Kai - - 2013
: Chronic wounds are biochemically complex and are associated with insufficient cell proliferation, angiogenesis, and extracellular matrix remodeling. The mechanisms by which pulsed radiofrequency energy modulates wound healing are still unclear. : Db/db mice were wounded and exposed to pulsed radiofrequency energy. Gross closure, cell proliferation, and morphometric analysis of ...
Bonita Raphael - - 2013
Cancer chemotherapy has improved over the years with the advent of newer agents, including more targeted chemotherapeutic drugs, resulting in better patient survival. However, with continued use and patient exposure to these drugs, important cardiovascular adverse effects are becoming realized, such as left ventricular dysfunction and heart failure, myocardial ischemia, ...
Spring Philipp - - 2013
: Birt-Hogg-Dubé Syndrome (BHD) is a rare condition, transmitted as an autosomal-dominant trait. The etiology is due to a mutation in the BHD gene, which encodes folliculin (FLCN), located on chromosome 17p. The skin changes observed are benign skin tumors consisting of hamartomas of the hair follicle with dermal changes. ...
Heydari Seyed-Taghi - - 2013
Objective: To analyze the time factor in road traffic accidents (RTAs) in Fars Province of Iran. Methods: This study was conducted in Fars Province, Iran from November 22, 2009 to November 21, 2011. Victims'information consisted of age, sex, death toll involving dri- vers or passengers of cars, motorcycles and pedestrians, ...
Aliu Oluseyi - - 2013
: For surgical treatment of thumb carpometacarpal joint arthritis, current evidence suggests that simple trapeziectomy is as effective as and may be safer than trapeziectomy and ligament reconstruction with or without tendon interposition. The authors examined whether current practice patterns in the surgical treatment of thumb carpometacarpal joint arthritis reflect ...
Sobrino Justin - - 2013
Currently, long-term outcomes are significant because health care system changes will likely lead to a single payment for each occurrence of care, including readmissions-the "bundled payment" system. Therefore, it is essential to understand the outcomes of trauma patients discharged alive from trauma centers. This article reviews the current knowledge base ...
Chen Ying-Hui - - 2013
OBJECTIVE: To evaluate apoptotic effects of cisplatin and cordycepin as single agent or in combination with cytotoxicity in oral cancer cells. METHODS: The influences of cisplatin (2.5 μg/mL) and/or cordycepin treatment (10 or 100 μmol/L) to human OC3 oral cancer cell line were investigated by morphological observation for cell death ...
Martín-Antonio B - - 2013
Allo-SCT has a strong curative potential for AML patients mainly due to a GVL effect. Unfortunately, GvL and GVHD are intimately linked. IFN regulatory factor-3 (IRF3), by modulating innate immune reactions, could impact on the incidence and intensity of GVL and GVHD. We analyzed two gene variants in IRF3 (rs7251 ...
Garg Swati - - 2013
/st> Despite recommendations for children to have a dental visit by the age of 1 year, access to dental care for young children, including children enrolled in Medicaid, remains limited. The authors conducted a survey to assess the availability of dentists to see young children enrolled in Medicaid managed care ...
- - 2013
Patients with sickle cell disease commonly experience episodes of extreme pain that prompt them to seek care in the ED. However, emergency providers sometimes mistake these patients as drug-seekers, delaying effective pain relief and often resulting in under-treatment that can prolong suffering and result in repeat visits. Experts recommend development ...
Davis Margot - - 2013
Cardiovascular toxicity is one of the most feared complications of cancer treatment. Recent advances in oncologic therapies have resulted in improved cancer outcomes but also a new set of cardiovascular adverse effects. Common toxicities include left ventricular dysfunction/heart failure, hypertension, and myocardial ischemia. Accurate risk stratification allows avoidance of potentially ...
Fu De-Jie - - 2013
Objective: The effect of tranexamic acid (TA) on patients receiving total knee arthroplasty (TKA) has been reported in many small clinical trials. But single trials are not sufficient enough to clarify the effectiveness and safety of TA. So, we carried out a meta-analysis of randomized controlled trials to investigate the ...
Chuback Jennifer E - - 2013
: Internationally, plastic surgery societies have placed an increasing emphasis on the importance of evidence-based medicine. The authors aimed to categorize levels of evidence of podium presentations at three major North American plastic surgical meetings, and to assess the factors associated with a higher level evidence. : Presentations at the ...
Bassetto Franco - - 2013
: No perfect solution yet exists for dermal fillers. The authors hypothesized that autologous dermis can be processed in an operator-friendly manner and adopted in selected patients as a filler, following the principle of replacing "like with like." : The authors designed a prototype "cutting chamber" to morsel dermis into ...
Berry Justin W - - 2013
Our objective was to investigate the incidence of musculoskeletal injuries sustained by elite level curling athletes during international competition. This study was conducted during the 2008 World Men's Curling Championships. All registered athletes and the tournament medical team were given report forms for documenting injuries that occurred during the tournament. ...
Adams Jenny - - 2013
Six male firefighters who were referred to phase II cardiac rehabilitation after coronary revascularization participated in a specialized regimen of high-intensity, occupation-specific training (HIOST) that simulated firefighting tasks. During each session, the electrocardiogram, heart rate, and blood pressure were monitored, and the patients were observed for adverse symptoms. No patient ...
Greenstein Gary - - 2013
/st> Increased stress (force) on prostheses induces strain (deformation) in the peri-implant bone. Elevated stress and strain could result in the failure of implants that support prostheses. However, the survival rate of implants supporting prostheses under increased stress is high. Either the bone is stronger than expected or it adapts ...
Amirlak Bardia - - 2013
: Cone beam computed tomography allows for a significantly lower radiation dose than conventional computed tomographic scans, with generation of accurate images of the maxillofacial skeleton. The authors investigated its accuracy in the volumetric analysis of alveolar cleft defects and simulated bone grafts. : Five simulated alveolar clefts were created ...
Slater Emily P - - 2013
High-risk individuals of familial pancreatic cancer (FPC) families are considered to be good candidates for screening programs to detect early PC or its high-grade precursor lesions, especially pancreatic intraepithelial neoplasia (PanIN) 2/3 lesions. There is a definite need for diagnostic markers as neither reliable imaging methods nor biomarkers are available ...
Trikha Vivek - - 2013
Concomitant dislocation of the tarsometatarsal and metatarsophalangeal joints of foot is an extremely rare injury. Such injuries presenting in a single or adjacent dual rays have been described in few cases previously. We describe such an injury in adjacent three metatarsals of a polytrauma patient. These injuries are likely to ...
Ma Tian - - 2013
Considerable evidence indicates that type 1 T helper (Th1)- and Th17-mediated immune responses promote the formation of atherosclerotic plaques while that CD4(+)CD25(+)Foxp3(+) regulatory T cells (Tregs) have a protective effect. However, the functions of diverse CD4(+) lymphocyte subsets in plaque rupture remain poorly understood because of a shortage of satisfactory ...
Wong C H - - 2013
Aberrant regulation of the pRB/E2F1 pathway has been invariably linked to inappropriate proliferation and/apoptosis in human cancers. Therefore, understanding the intricacies of the signaling pathway and identification of novel E2F1 targets involved in apoptosis could pave way for new therapeutic manipulation. Here, we identified CTSL2 (cathepsin L2/cathepsin V) as a ...
Ewing James I - - 2013
A group from Texas Oncology and Baylor Charles A. Sammons Cancer Center traveled to Huê´, Vietnam, as part of Health Volunteers Overseas. From February 21 to March 6, 2012, five Baylor Sammons medical oncologists and an oncology nurse worked with a medical oncologist and a surgeon at the Huê´ College ...
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