Search Results
Results 351 - 400 of 2350
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Borsboom Denny - - 2013
In network approaches to psychopathology, disorders result from the causal interplay between symptoms (e.g., worry → insomnia → fatigue), possibly involving feedback loops (e.g., a person may engage in substance abuse to forget the problems that arose due to substance abuse). The present review examines methodologies suited to identify such ...
Yang Shixing - - 2013
Little information on the epidemiology and pathogenicity of porcine enterovirus 9 (PEV-9) is available. The present study investigated the prevalence of PEV-9 in pig populations in middle and eastern China using reverse transcriptase (RT)-PCR. All 14 sampled farms were positive for PEV-9 and the overall prevalence of infection in the ...
Shaw Richard E - - 2013
OBJECTIVESPrior studies have found that cardiac surgery patients receiving blood transfusions are at risk for increased mortality and morbidity following surgery. It is not clear whether this increased risk occurs across all haematocrit (HCT) levels. The goal of this study was to compare operative mortality in propensity-matched cardiac surgery patients ...
Long Huang - - 2013
OBJECTIVE: The objective of this paper is to investigate a profile on circulatory renin-angiotensin system (RAS) activity in hypercholesterolemic (HC) patients treated with statins. METHODS: Eighteen primary HC patients and 18 sex- and age-matched healthy adults were included in this study as controls. Total cholesterol (TC), triglyceride (TG), LDL-C, blood ...
Hu Yilin - - 2013
The iron-molybdenum cofactor, or the M-cluster, serves as the active site of molybdenum nitrogenase. Arguably one of the most complex metal cofactors in biological systems, the M-cluster is assembled through the formation of an 8Fe core prior to the insertion of Mo and homocitrate into this core. Here, we review ...
Gonçalves Patricia Furtado - - 2013
Background: Matrix metalloproteinases (MMPs) are a family of host-derived proteinases reported to mediate multiple functions associated with periodontal destruction and inflammation. We have previously reported high MMP levels in African-American children with localized aggressive periodontitis (LAP). However, little is known about MMP reductions in gingival crevicular fluid (GCF) after therapy. ...
Arntzen Magnus Øverlie - - 2013
Programmed cell death is a ubiquitous process of utmost importance for the development and maintenance of multicellular organisms. More than ten different types of programmed cell death forms have been discovered. Several proteomics analyses have been performed to gain insight in proteins involved in the different forms of programmed cell ...
Zubairi Ali Bin - - 2013
BACKGROUND: Leukotriene receptor antagonists (LTRAs) are well established in the management of outpatient asthma. However, there is very little information as to their role in acute asthma exacerbations. We hypothesized that LTRAs may accelerate lung function recovery when given in an acute exacerbation. METHODS: A randomized, double blind, placebo-controlled trial ...
Lamprecht Bernd - - 2013
BACKGROUND: Current guidelines recommend spirometry to confirm a diagnosis of chronic obstructive pulmonary disease (COPD). AIMS: To investigate whether a self-reported diagnosis of COPD is associated with prior spirometry and whether a correct diagnosis of COPD is more likely when spirometry was performed. METHODS: We used data from the population-based ...
Shi Wei - - 2013
Two-dimensional NPxyT and isostress-osmotic (N2PxyTf1) Monte Carlo simulations were used to compute the density and gas absorption properties of the ionic liquid (IL) 1-n-hexyl-3-methylimidazolium bis(Trifluoromethylsulfonyl)amide ([hmim][Tf2N]) confined in silica slit pores (25-45 Å). Self-diffusivity values for both gas and IL were calculated from NVE molecular dynamics simulations using both smooth ...
Davidovich Daniel - - 2013
Ectopic fat deposition has been associated with lipotoxicity and derangement in local and systemic metabolism, insulin resistance, cardiac dysfunction, atherosclerosis, local, and systemic inflammation. The mechanisms and potentially detrimental effects of such an accumulation should be fully investigated in order to establish preventive strategies. The aim of this review is ...
Kint Cyrielle - - 2013
Abstract Obg proteins (also known as ObgE, YhbZ and CgtA) are conserved P-loop GTPases, essential for growth in bacteria. Like other GTPases, Obg proteins cycle between a GTP-bound ON and a GDP-bound OFF state, thereby controlling cellular processes. Interestingly, the in vitro biochemical properties of Obg proteins suggest that they ...
Ice Ryan J - - 2013
Aurora A Kinase (AURKA) is overexpressed in 96% of human cancers and is considered an independent marker of poor prognosis. While the majority of tumors have elevated levels of AURKA protein, few have AURKA gene amplification, implying that posttranscriptional mechanism regulating AURKA protein levels are significant. Here we show that ...
Delahay R J - - 2013
SUMMARY We describe epidemiological trends in Mycobacterium bovis infection in an undisturbed wild badger (Meles meles) population. Data were derived from the capture, clinical sampling and serological testing of 1803 badgers over 9945 capture events spanning 24 years. Incidence and prevalence increased over time, exhibiting no simple relationship with host ...
Ezeh Uche - - 2013
Background:The described phenotype of the Polycystic Ovary Syndrome (PCOS) has been primarily based on findings in a referred (self or otherwise) population. It is possible that the phenotype of PCOS would be different if the disorder were to be detected and studied in its natural (unbiased) state.Objective:To compare the phenotype ...
Hardcastle Sarah J - - 2013
BACKGROUND: Intensive diet and physical activity interventions have been found to reduce cardiovascular disease (CVD) risk, but are resource intensive. The American Heart Association recently recommended motivational interviewing (MI) as an effective approach for low-intensity interventions to promote health-related outcomes such as weight loss. However, there is limited research evaluating ...
Coleman Eric A - - 2013
Abstract The Centers for Medicare and Medicaid Services (CMS) has launched the Partnership for Patients initiative, promising a 20% reduction in readmissions nationally across all payers by December 31, 2013. To address this ambitious goal, CMS has awarded grants to Hospital Engagement Networks, Pioneer Accountable Care Organizations, and the Community-based ...
Jouikov Viatcheslav - - 2013
An easy process for allylation and benzylation of different carbon materials, primarily of glassy carbon, in acetonitrile solutions containing tetraalkyammonium salts is described. The method relies on the capability of Csp2-zones of glassy carbon (graphite and fullerene-like inclusions) to be anodically charged at potentials > 1.5 V vs. Ag/AgCl to ...
Abdulsadda Ahmad T - - 2013
As a flow-sensing organ, the lateral line system plays an important role in various behaviors of fish. An engineering equivalent of a biological lateral line is of great interest to the navigation and control of underwater robots and vehicles. A vibrating sphere, also known as a dipole source, can emulate ...
Neumann Charlotte G - - 2013
OBJECTIVE: To examine the effects of three different school snacks on morbidity outcomes. DESIGN: Twelve schools were randomized to either one of three feeding groups or a Control group. There were three schools per group in this cluster randomized trial. Children in feeding group schools received school snacks of a ...
Trevithick John R - - 2013
Abstract Purpose: Pycnogenol was used (a) to study its antioxidant activity, (b) to study its effects on lens integrity in organ culture and (c) in vivo to determine whether it could reduce the damage in model diabetic cataract. Methods: For (a) our luminescent antioxidant assay was used, (b) lenses were ...
Gentle Madeleine E - - 2013
TGFβ signaling plays a central role in the development of acute and chronic kidney diseases. Previous in vivo studies involved systemic alteration of TGFβ signaling, however, limiting conclusions about the direct role of TGFβ in tubular cell injury. Here, we generated a double transgenic mouse that inducibly expresses a ligand-independent ...
De Vita E - - 2013
BACKGROUND AND PURPOSE:Inherited prion diseases represent over 15% of human prion cases and are a frequent cause of early onset dementia. The purpose of this study was to define the distribution of changes in cerebral volumetric and microstructural parenchymal tissues in a specific inherited human prion disease mutation combining VBM ...
Joo Min J - - 2013
Abstract Guidelines that recommend spirometry to confirm airflow obstruction among patients with suspected COPD are not routinely followed. We conducted a qualitative study to identify attitudes and barriers of primary care physicians to performing spirometry for patients with possible COPD. We conducted four focus groups, each with three primary care ...
Pagnamenta Alberto - - 2013
The time constant of the pulmonary circulation, or product of pulmonary vascular resistance (PVR) and compliance (Ca), called the RC-time, has been reported to remain constant over a wide range of pressures, etiologies of pulmonary hypertension, and treatments. We wondered whether increased wave reflection on proximal pulmonary vascular obstruction, like ...
Al-Qahtani Saeed - - 2013
Objective: We present our experience in the minimal invasive management of post-operative complications associated with urinary diversions using ureteral access sheath (UAS) in antegrade approach. Patients and Methods: From 2005 to 2011, 21 antegrade flexible ureteroscopy (F-URS) were performed in 17 patients with a urinary diversion. Urinary diversions in this ...
Roberts James R - - 2013
Background. Control of environmental triggers (ETs) greatly improves asthma outcomes in children. Disseminating these findings to general pediatricians has not been well established. Methods. After delivering a structured and standardized presentation on ET identification and control to pediatricians, we surveyed them about knowledge and practices of ET assessment and management. ...
Coletta Adriana - - 2013
BACKGROUND: It is recommended that endurance athletes consume carbohydrate (CHO) supplements, providing 6-8% CHO concentration, during exercise > 60 minutes to improve athletic performance. Recently research has compared carbohydrate-protein (CHO-P) supplementation to the traditionally used CHO supplementation during endurance exercise, following these supplementation recommendations, in controlled settings, but not under ...
Clarke Luka A - - 2013
BACKGROUND: Microarray studies related to cystic fibrosis (CF) airway gene expression have gone some way in clarifying the complex molecular background of CF lung diseases, but have made little progress in defining a robust "molecular signature" associated with mutant CFTR expression. Disparate methodological and statistical analyses complicate comparisons between independent ...
Park Tai Hwan - - 2013
BACKGROUND AND PURPOSE: Several stroke risk scores for prediction of functional outcome have been developed, but rarely validated in Asian populations. We assessed the validity of the iScore, recently developed from Canadian stroke population, in an Asian stroke population from Korea. METHODS: We applied the iScore to 4061 eligible participants ...
Koçak Aslıhan Yonca - - 2013
Abstract Methotrexate (MTX) is an effective but potentially toxic treatment for psoriasis. We describe a patient who administered 20 mg daily of MTX for 5 d and presented with ulcerated and necrotic lesions on the psoriatic plaques, mouth erosions and hair loss. However, his psoriatic plaques and ulcerations totally healed rapidly within ...
Cho Jae Hyung - - 2013
BACKGROUND: Ventricular septal rupture is a potentially fatal complication of acute myocardial infarction. Its incidence has declined with modern reperfusion therapy. In the era of percutaneous coronary interventions, it occurs a median of 18--24 hours after myocardial infarction and is most commonly associated with anterior myocardial infarction. We present a ...
Xu Chuan - - 2013
Cancer stem-like cells (CSLCs) are crucial in tumor initiation and progression, however, the underlying mechanism for the self-renewal of cancer cells remains undefined. In the study, immunohistochemical analysis of specimens freshly excised from patients with lung adenocarcinoma (LAC) showed that high expression of insulin-like growth factor 1 receptor (IGF-1R) in ...
Shrewsberry Adam Buddy - - 2013
Purpose: Correct length of ureteral stent is important in minimizing post-placement discomfort and stent migration. We describe and validate a method to accurately measure ureteral length. Materials and Methods: Ureteral length in 48 patients undergoing ureteral stent placement for urolithiasis was measured by CT (total thickness of axial slices between ...
Budenz Donald L - - 2013
IMPORTANCE Multiple studies have found an increased prevalence, younger age at onset, and more severe course of glaucoma in people of African descent, but these findings are based on studies conducted outside Africa. OBJECTIVE To determine the prevalence of glaucoma in an urban West African population of adults. DESIGN AND ...
Li Lin - - 2013
Abstract 1. In the present study, we investigated the impact of 1.0% ropivacaine on the ultrastructure and proteome of the rat spinal cord. 2. Rats received three injections (90-min intervals, 0.2 mL/kg) of 0.9% NaCl, 0.5% ropivacaine or 1.0% ropivacaine via an implanted intrathecal catheter. Transmission electron microscopy was performed to ...
Miao Xiao - - 2013
BACKGROUND: Cardiovascular diseases remain a leading cause of the mortality world-wide, which is related to several risks, including the life style change and the increased diabetes prevalence. The present study was to explore the preventive effect of zinc on the pathogenic changes in the aorta. METHODS: A genetic type 1 ...
Bienaimé Frank - - 2013
Kidney transplant recipients usually have low vitamin D levels, especially in the early posttransplantation period, but the association between vitamin D status with renal outcomes is not well described in this population. Here, we studied a prospective cohort of 634 kidney recipients who underwent transplantation at a single institution between ...
Pablico-Lansigan Michele H - - 2013
Magnetic particle imaging (MPI) is an emerging biomedical imaging technology that allows the direct quantitative mapping of the spatial distribution of superparamagnetic iron oxide nanoparticles. MPI's increased sensitivity and short image acquisition times foster the creation of tomographic images with high temporal and spatial resolution. The contrast and sensitivity of ...
Burt Morton G - - 2013
Context:Measurement of plasma cortisol by immunoassay after ACTH1-24 stimulation is used to assess the hypothalamic-pituitary-adrenal (HPA) axis. Liquid chromatography-tandem mass spectrometry (LCMS) has greater analytical specificity than immunoassay and equilibrium dialysis allows measurement of free plasma cortisol.Objective:We investigated the use of measuring total and free plasma cortisol by LCMS and ...
Ou Shuching - - 2013
We investigate temperature-dependence of free energetics with two single halide anions, I- and Cl-, crossing the aqueous liquid-vapor interface through molecular dynamics simulations. The result shows that I- has a modest surface stability of 0.5 kcal/mol at 300 K and the stability decreases as the temperature increases, indicating the surface ...
Yilmaz Mehmet - - 2013
Nanoscale materials often have stochastic material properties due to a random distribution of material defects and an insufficient number of defects to ensure a consistent average mechanical response. Current methods to measure the mechanical properties employ MEMS-based actuators. The nanoscale specimens are typically mounted manually onto the load platform, so ...
Loukidou Evangelia - - 2013
Over the last three decades significant efforts have been made in many European countries to move away from a mental health system dominated by institutional care towards one whereby the main emphasis is on providing care and support within the community. Although the time of starting the reforms, their pace, ...
Yan Pisong - - 2013
Abstract Purpose: To evaluate the changes in posterior corneal surface (Q value and elevation) measured with Pentacam after femtosecond laser assisted Sub-Bowman Keratomileusis (SBK). Methods: The Q values and elevation of posterior corneal surface were determined in 166 myopic/myopic astigmatism eyes of 88 patients using Scheimpflug imaging (Pentacam; Oculus, Wetzlar, ...
Liu Qi - - 2013
Two novel 2D Ln-Cd HMOFs [Ln2Cd3(EDTA)3(H2O)11](H2O)14 (Ln = Sm 1; Eu 2; H4EDTA = ethylene diamine tetraacetic acid) based on nanosized heart-like Ln6Cd6O12 wheel-clusters were hydrothermally synthesized and characterized. The luminescence sensing of 2 to the polarization and concentration of cations was discussed.
Eakin Deborah K - - 2013
Abstract Age differences in feeling-of-knowing (FOK) accuracy were examined for both episodic memory and semantic memory. Younger and older adults either viewed pictures of famous faces (semantic memory) or associated non-famous faces and names (episodic memory) and were tested on their memory for the name of the presented face. Participants ...
Huang Liang - - 2013
Composite films of graphene oxide (GO) sheets and silk fibroin (SF) with layered structures have been prepared by facile solution casting of SF-GO hydrogels. The as-prepared composite film containing 15% (by weight, wt%) of SF shows a high tensile strength of 221 ± 16 MPa and a failure strain of ...
Tinuoye Olaitan - - 2013
INTRODUCTION: Studies suggest an association between secondhand smoke exposure and the development of childhood asthma. Several countries are considering legislation to protect children from exposure. METHODS: A systematic review was conducted using MEDLINE, Embase, PubMed, and Web of Knowledge databases and a random effects meta-analysis was undertaken. Heterogeneity was assessed ...
Suranyi Eva - - 2013
Purpose: To evaluate the effect of plaque radiation therapy using beta-radioactive isotope for anterior segment tumors on the density and morphology of endothelial cells. 
Methods: Endothelial cell density (ECD) and morphometry in 15 eyes of 15 patients with ciliary body tumor was examined prior to and 6 months after radiation ...
Onder Graziano - - 2013
Older patients are particularly vulnerable to adverse drug reactions (ADRs) because age is associated with changes in pharmacokinetics and pharmacodynamics that may alter drug metabolism. In addition, other conditions, commonly observed in older adults, may increase the risk of ADRs in the older population (including polypharmacy, comorbidity, cognitive and functional ...
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