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Scott C E H - - 2013
The lateral compartment is predominantly affected in approximately 10% of patients with osteoarthritis of the knee. The anatomy, kinematics and loading during movement differ considerably between medial and lateral compartments of the knee. This in the main explains the relative protection of the lateral compartment compared with the medial compartment ...
Azegami S - - 2013
Slipped capital femoral epiphysis (SCFE) is relatively common in adolescents and results in a complex deformity of the hip that can lead to femoroacetabular impingement (FAI). FAI may be symptomatic and lead to the premature development of osteoarthritis (OA) of the hip. Current techniques for managing the deformity include arthroscopic ...
Lehmann T G - - 2013
The reported prevalence of an asymptomatic slip of the contralateral hip in patients operated on for unilateral slipped capital femoral epiphysis (SCFE) is as high as 40%. Based on a population-based cohort of 2072 healthy adolescents (58% women) we report on radiological and clinical findings suggestive of a possible previous ...
Sandiford N - - 2013
We present the extended follow-up (≥ 20 years) of a series of fully hydroxyapatite-coated femoral components used in 72 primary total hip replacements (THRs). Earlier results of this cohort have been previously published. All procedures were performed between 1986 and 1991. The series involved 45 women and 15 men with ...
Liebs T R - - 2013
We investigated whether an asymmetric extension gap seen on routine post-operative radiographs after primary total knee replacement (TKR) is associated with pain at three, six, 12 and 24 months' follow-up. On radiographs of 277 patients after primary TKR we measured the distance between the tibial tray and the femoral condyle ...
Hino K - - 2013
There are several methods for evaluating stability of the joint during total knee replacement (TKR). Activities of daily living demand mechanical loading to the knee joint, not only in full extension, but also in mid-flexion. The purpose of this study was to compare the varus-valgus stability throughout flexion in knees ...
Hutchison A M - - 2013
We conducted a randomised controlled trial to determine whether active intense pulsed light (IPL) is an effective treatment for patients with chronic mid-body Achilles tendinopathy. A total of 47 patients were randomly assigned to three weekly therapeutic or placebo IPL treatments. The primary outcome measure was the Victorian Institute of ...
Park H-W - - 2013
Severe hallux valgus deformity is conventionally treated with proximal metatarsal osteotomy. Distal metatarsal osteotomy with an associated soft-tissue procedure can also be used in moderate to severe deformity. We compared the clinical and radiological outcomes of proximal and distal chevron osteotomy in severe hallux valgus deformity with a soft-tissue release ...
Henry P D G - - 2013
Latissimus dorsi tendon transfer (LDTT) is technically challenging. In order to clarify the local structural anatomy, we undertook a morphometric study using six complete cadavers (12 shoulders). Measurements were made from the tendon to the nearby neurovascular structures with the arm in two positions: flexed and internally rotated, and adducted ...
Henseler J F - - 2013
Surgical repair of posterosuperior rotator cuff tears has a poorer outcome and a higher rate of failure compared with repairs of supraspinatus tears. In this prospective cohort study 28 consecutive patients with an irreparable posterosuperior rotator cuff tear after failed conservative or surgical treatment underwent teres major tendon transfer. Their ...
Roche C P - - 2013
This study provides recommendations on the position of the implant in reverse shoulder replacement in order to minimise scapular notching and osteophyte formation. Radiographs from 151 patients who underwent primary reverse shoulder replacement with a single prosthesis were analysed at a mean follow-up of 28.3 months (24 to 44) for ...
Qi M - - 2013
In a retrospective cohort study we compared the clinical outcome and complications, including dysphagia, following anterior cervical fusion for the treatment of cervical spondylosis using either a zero-profile (Zero-P; Synthes) implant or an anterior cervical plate and cage. A total of 83 patients underwent fusion using a Zero-P and 107 ...
Dienstknecht T - - 2013
We report the functional and socioeconomic long-term outcome of patients with pelvic ring injuries. We identified 109 patients treated at a Level I trauma centre between 1973 and 1990 with multiple blunt orthopaedic injuries including an injury to the pelvic ring, with an Injury Severity Score (ISS) of ≥ 16. ...
Capanna R - - 2013
We welcome letters to the Editor concerning articles that have recently been published. Such letters will be subject to the usual stages of selection and editing; where appropriate the authors of the original article will be offered the opportunity to reply.
Yang Hee Kyung - - 2013
We present a computerized method of measuring binocular alignment using a selective wavelength filter and an infrared camera, and validate the efficacy of automated image analysis compared to the gold standard prism and alternate cover test (PCT). A prospective observational pilot study was performed on 30 subjects with intermittent exotropia, ...
Lee Sieun - - 2013
We compared the reproducibility and mutual agreement of the subfoveal choroidal thickness measurements by expert raters and an automated algorithm in enhanced depth imaging optical coherence tomography (EDI-OCT) images of eyes with nonneovascular age-related macular degeneration (AMD). We recruited 44 patients with nonneovascular AMD and EDI-OCT images were acquired. Subfoveal ...
Sng Chelvin C - - 2013
We determined the ocular biometric and demographic factors associated with iris parameters in Singaporean Chinese persons from a population-based sample. Subjects were participants in the Singapore Chinese Eye Study, a population-based cross-sectional study of eye disease. Anterior segment optical coherence tomography images were analyzed using customized software to measure iris ...
Sim Dawn A - - 2013
To describe novel segmentation protocols for choroidal layers, Sattler's medium and Haller's large vessel layers, using enhanced depth imaging optical coherence tomography (EDI-OCT), and to examine the repeatability and reproducibility of these measurements in eyes with diabetic retinopathy. Fifty-one patients with Type 2 diabetes mellitus were imaged using custom EDI ...
Gorin Yves - - 2013
Watanabe et al. report that Nox4 NADPH oxidase catalytic moiety and the subunit p22(phox) mediate the increase in oxidative stress and human tubular epithelial cell injury induced by p-cresyl sulfate, a protein-bound uremic toxin. These findings could be instrumental for the design of novel therapeutic intervention utilizing small-molecule inhibitors specifically ...
Chaudhry Shazia H SH Department of Epidemiology and Community Medicine, University of Ottawa, Ottawa, ON, - - 2013
Cluster randomized trials (CRTs) complicate the interpretation of standard research ethics guidelines for several reasons. For one, the units of allocation, intervention, and observation often may differ within a single trial. In the absence of tailored and internationally accepted ethics guidelines for CRTs, researchers and research ethics committees have no ...
Wehmeyer Michael L ML University of Kansas, 1200 Sunnyside Ave., Lawrence, KS 66045, USA. - - 2013
The World Health Organization's International Classification of Diseases (ICD) is the most important diagnostic tool, worldwide, to ensure that people with intellectual and developmental disabilities receive the supports they need to live richer, fuller lives. And yet, the ICD has naming conventions that create a conundrum for the field, requiring ...
Koola Maju Mathew MM Maryland Psychiatric Research Center, University of Maryland School of Medicine, Baltimore, USA. - - 2013
We examined the prevalence of childhood (≤ 18 years) physical and sexual abuse reported among patients admitted to the psychiatric inpatient service and the differential rates of this abuse associated with psychiatric diagnoses. This study consisted of a retrospective chart review of 603 patients admitted to a psychiatric ward during ...
Kiesswetter E E Institute for Biomedicine of Aging, Friedrich-Alexander Universität Erlangen-Nürnberg, Nürnberg, Germany. - - 2013
The aims of this work were (a) to provide a detailed description of the association between nutritional (Mini Nutritional Assessment; MNA®) and functional status in a sample of older adults receiving home care, using both questionnaire- and performance-based functional methods, and (b) to investigate the impact of different MNA subscales ...
Gentile S S Laboratoire de Santé Publique, EA 3279, Faculté de Médecine, Université de La Méditerranée, Marseille, - - 2013
To identify independent risk factors of mortality among elderly patients in the 3 months after their visit (T3) to an emergency department (ED). Prospective cohort study. University hospital ED in an urban setting in France. One hundred seventy-three patients aged 75 and older were admitted to the ED over two ...
Roqué M M Institut de l'Envelliment, Universitat Autònoma de Barcelona, Sant Pau Institute of Biomedical Research (IIB-Sant Pau), Barcelona, Spain. - - 2013
The objective of this study is to assess the nutritional status, measured by the MNA, in community-dwelling elderly individuals with dementia and to identify clinical risk factors for nutritional risk or malnutrition. Cross-sectional analysis of a cluster randomized clinical trial (Nutrialz). Community-dwelling individuals attending dementia clinics. 940 individuals. The clinical ...
Sargento L L Heart Failure unit, Cardiology department, Pulido Valente Hospital, Lisbon north Hospital Centre, Lisbon, Portugal. - - 2013
The prevalence of malnutrition in ambulatory patients with heart failure is difficult to determine, depending on the timing and methodology. To determine the nutritional status of outpatients with systolic heart failure with the Mini Nutritional Assessment (MNA) full and short-form versions, and evaluate its relationship with the short-term prognosis, biomarkers ...
Alfonso-Rosa R M RM Department of Physical Education and Sports, University of Seville, Seville, - - 2013
To explore the relationship between nutritional status, functional capacity and health-related quality of life (HRQoL) in older adults with type 2 diabetes (T2DM). Cross-sectional study. Forty two non-insulin dependent older adults from a primary care center in Seville, Spain. Function was assessed with a battery of standardized physical fitness tests. ...
Duron E E AP-HP, groupe hospitalier Paris-centre. Broca Hospital, Department of Geriatrics, Paris, France. - - 2013
Some studies have highlighted the difficulty for physicians to evaluate patient's ability to consent to bio-medical research in the elderly population. The University of California Brief Assessment of Capacity to Consent (UBACC) is a rapid questionnaire to assess the ability to consent, previously validated among schizophrenic patients. To evaluate the ...
Breeman S S Health Services Research Unit, University of Aberdeen, Aberdeen, AB25 2ZD, - - 2013
There is conflicting evidence about the merits of mobile bearings in total knee replacement, partly because most randomised controlled trials (RCTs) have not been adequately powered. We report the results of a multicentre RCT of mobile versus fixed bearings. This was part of the knee arthroplasty trial (KAT), where 539 ...
Dinneen A A The Royal Surrey County Hospital NHS Foundation Trust, Department of Trauma & Orthopaedics, Egerton Road, Guildford, Surrey GU2 7XX, UK. - - 2013
Cut-off values with highest sensitivity and specificity for the synovial fluid white cell and differential count will facilitate the accurate diagnosis of infection in total knee (TKR) and total hip replacement (THR). All patients undergoing revision TKR or THR for suspected prosthetic joint infection between 2009 and 2011 at two ...
- - 2013
New governance arrangements, including an operational board Chief executive's update on recent progress Requirement on vets to disclose convictions These were among matters discussed by the RCVS Council at its meeting on March 7. The RCVS President, Jacqui Molyneux, chaired the meeting, which was held at Belgravia House, London SW1P.
Osterbrink J - - 2013
BACKGROUND: High healthcare needs are evident for pain caused by cancer. Those affected are not only looking for help in acute inpatient structures but also for a much larger part in outpatient care structures. To avoid mistreatment, undertreatment or overtreatment of pain in people with cancer, it is necessary to ...
Halpern B S - - 2013
This review article gives a detailed overview regarding the growing importance of tumor boards in the daily clinical life. Improved diagnostic and therapeutic options for oncologic diseases lead to an increased complexity in patient management, which can only be handled optimally by a team of specialists. Within this process radiology ...
Brunkhorst J - - 2013
Sectorally segregated healthcare structures are seen as a major reason for deficits in quality and efficiency. With the introduction of §§ 140 a ff. SGB V, the sectoral splitting into outpatient, inpatient and rehabilitative services will be eliminated. This is especially true for the requirements of state-of-the-art multidisciplinary and comprehensive pain therapy. ...
Kern K-U - - 2013
OBJECTIVES: The successful therapy of phantom pain remains a major challenge, because the underlying pathophysiological mechanisms are still not fully understood. A therapeutic approach with tapentadol has not been described so far. PATIENTS AND METHODS: Five patients suffering upper and lower extremity phantom pain were successfully treated with tapentadol (prolonged ...
Lörincz B B - - 2013
Transoral robotic surgery (TORS) using the da Vinci® System is being performed increasingly on an international level. Particularly in the US, TORS is a common and popular technique. It has several advantages over the alternative minimally invasive surgical technique of laser surgery: the 3D-HD lens generates a magnified, three dimensional deep-field ...
Hahn U - - 2013
Cataract surgery is scheduled for a federal program for quality improvement across the different sectors of care (outpatient care and hospitals). In case of implementation not only ophthalmic surgeons but all ophthalmologists would have to contribute to the documentation. Urgency, potential benefits and limitations of a compulsory compared to a ...
Sollberger D - - 2013
Despite the reform efforts of the last decades modern acute psychiatry still stands between conflicting priorities in everyday practice. The protection of patient autonomy might conflict with a regulatory mandate of psychiatry in societal contexts and the necessity of coercive measures and involuntary treatment might become problematic with respect to ...
- - 2013
Given the recent horsemeat scandal, the National Office for Animal Health's fourth food chain conference, held at the Royal Society in London on March 6, was particularly timely. Representatives from all areas of the food chain, from regulators through to retailers, came together to discuss some of the myths surrounding ...
Schulte P - - 2013
BACKGROUND: Schwannomas (neurinomas) are among the most frequent peripheral nerve tumors. Nevertheless, these are seldom located in the lower extremities in association with the femoral nerve. CLINICAL PRESENTATION: In this case, the occurrence of a schwannoma adjacent to the femoral nerve is described in a patient presenting with nonspecific pain ...
Innes John - - 2013
John Innes discusses developments in treating common articular disorders, such as dysplasia, cruciate ligament rupture and arthritis, from surgical and medical options to the promising targeted genetic medicine.
Schneider A-M - - 2013
Cross-sectoral clinical pathways for chronic pain patients in standard and routine care are a major challenge for the German healthcare system. The Algesiologikum group has developed such clinical pathways including an essential infrastructure. Cooperation partners of the Algesiologikum group are two outpatient medical care units, one neurosurgery practice and four ...
Bajwa Paramjit K - - 2013
Global gene expression was analyzed in Saccharomyces cerevisiae T2 cells grown in the presence of hardwood spent sulphite liquor (HW SSL) and each of the three main inhibitors in HW SSL, acetic acid, hydroxymethyfurfural (HMF) and furfural, using a S. cerevisiae DNA oligonucleotide microarray. The objective was to compare the ...
Wei Y - - 2013
The molecular bases of myelodysplastic syndromes (MDS) are not fully understood. Trimethylated histone 4 lysine 3 (H3K4me3) is present in promoters of actively transcribed genes and has been shown to be involved in hematopoietic differentiation. We performed a genome-wide H3K4me3 CHIP-Seq analysis of primary MDS bone marrow (BM) CD34+ cells. ...
Zhang Jin-Lin - - 2013
Salt tolerance is an important economic trait for crops growing in both irrigated fields and marginal lands. The plant kingdom contains plant species that possess highly distinctive capacities for salt tolerance as a result of evolutionary adaptation to their environments. Yet, the cellular mechanisms contributing to salt tolerance seem to ...
Kido Takamasa - - 2013
The use of a petroleum-derived cleaning solvent for dry cleaning, instead of tetrachloroethylene (perchloroethylene, PCE), has increased. The cleaning solvent may induce immunological alteration. In this study, murine macrophage-lineage J774.1 cells were exposed to the cleaning solvent at 0, 25, 50, and 75 µg/ml or PCE at 0, 400, 600, 800, ...
Sakai Eiko - - 2013
Osteoclasts (OCLs) are multinucleated bone-resorbing cells that are differentiated by stimulation with receptor activator of nuclear factor kappa-B ligand (RANKL) and macrophage colony-stimulating factor. We recently demonstrated that regulation of heme-oxygenase 1 (HO-1), a stress-induced cytoprotective enzyme, also functions in OCL differentiation. In this study, we investigated effects of fisetin, ...
Ponnusamy K - - 2013
Biofouling is a serious problem on filter membranes of water purification systems due to formation of bacterial biofilms, which can be detrimental to the membrane performance. Biofouling occurs on membrane surface and therefore greatly influences the physical and chemical aspects of the surface. Several membranes including microfiltration, ultrafiltration, and reverse ...
Herman Katya M - - 2013
PURPOSE: Obesity is associated with impaired health-related quality of life (HRQL). As perceived constructs, self-rated health (SRH) and general life satisfaction (LS) might be more strongly related to perceived weight status than actual weight status. The aim was to assess agreement between perceived weight status and self-reported body mass index ...
Chaves Guilherme Maranhão - - 2013
Although yeasts belonging to the genus Candida are frequently seen as commensals in the oral cavity, they possess virulence attributes that contribute for pathogenicity. The aims of the present study were to study the prevalence of Candida spp. isolated from the oral cavity of renal transplant recipients and to analyze ...
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