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Pollock Carol A - - 2013
Directing the development of human embryonic stem cells into functional renal tubular cells has been limited by the lack of defined, reproducible differentiation and culture protocols. If these cells are to be used for in vitro testing or therapeutics, viability under bioreactor conditions is required. Narayanan et al. describe in ...
Yopp Justin Michael - - 2013
Men who are raising dependent children after their spouses or partners have died from cancer face unique challenges adjusting to single parenthood while managing their grief and the grief of their children. Unfortunately, the needs of those widowers have been overlooked in the clinical literature and no published interventions are ...
Sreekumar Anuradha - - 2013
Enzyme immunoassay for lipoprotein(a) [Lp(a)] using antibodies to both apoB and apo(a) subunits (a-B assay) is shown to be affected by differential masking of apoB by apo(a) and the presence of LDL-Lp(a) adducts. An apoB-independent immunoassay by capturing Lp(a) through its O-glycans on microplate-coated lectin jacalin and quantitation using peroxidase-labeled ...
Fisher W D - - 2013
There is currently limited information available on the benefits and risks of extended thromboprophylaxis after hip fracture surgery. SAVE-HIP3 was a randomised, double-blind study conducted to evaluate the efficacy and safety of extended thromboprophylaxis with the ultra-low molecular-weight heparin semuloparin compared with placebo in patients undergoing hip fracture surgery. After ...
Jeon Hong Jin - - 2013
Many previous studies have revealed that individuals with depression have higher thought of suicide, although not always exhibiting intent. We investigated the associated factors with respect to intent for suicide in the future. A total of 1584 adults were selected through a nationwide multistage probability sampling, randomly one person per ...
Takahashi Takayuki - - 2013
Ovulation is the process of liberating oocytes from the preovulatory follicles, and is observed in the ovaries of virtually all female vertebrate animals. Compared with mammalian species, there have been far fewer studies that address the ovulatory mechanisms of non-mammalian species. We have examined the molecular mechanism of follicle rupture ...
Mayer Deborah K - - 2013
The Oncology Nursing Society's (ONS's) mission is to promote excellence in oncology nursing and quality cancer care. But what does quality cancer care really mean? For me, it means that the care I want my family to receive is delivered to all-the best care, nothing less. And yet that doesn't ...
Manley Mollie - - 2013
To quantitatively define the anatomic insertions of the transverse carpal ligament (TCL) to the carpals. We dissected 5 fresh-frozen cadaver limbs, isolating the TCL. The ligament insertion sites into bone were clearly marked and photographed. We then used computer software to measure the area of insertion into the individual carpals. ...
Pizolato Raquel Aparecida - - 2013
The purpose of this study was to evaluate factors associated with temporomandibular disorder (TMD) in children. TMD clinical signs were evaluated using the Research Diagnostic Criteria for TMD (RDC/TMD; axis I), and subjective symptoms were evaluated using a structured questionnaire. Eighty-two children were selected, 40 with TMD (19 boys and ...
Rust Connie - - 2013
Although research has been conducted to address specific medical and psychosocial needs of breast cancer survivors, little has been done to address needs along the entire trajectory of care. One such need is chemobrain, a phenomenon recognized as an identifiable psychosocial cognitive change in breast cancer survivors. The purpose of ...
Gorin Yves - - 2013
Watanabe et al. report that Nox4 NADPH oxidase catalytic moiety and the subunit p22(phox) mediate the increase in oxidative stress and human tubular epithelial cell injury induced by p-cresyl sulfate, a protein-bound uremic toxin. These findings could be instrumental for the design of novel therapeutic intervention utilizing small-molecule inhibitors specifically ...
Josephson Allan M - - 2013
Families are the context for development. One key way families influence developing children is through family experience, which becomes part of the child's inner world. It is through this cognitive template that the child interprets the world and negotiates developmental challenges. This article reviews a continuum of family interventions targeting ...
Breeman S S Health Services Research Unit, University of Aberdeen, Aberdeen, AB25 2ZD, - - 2013
There is conflicting evidence about the merits of mobile bearings in total knee replacement, partly because most randomised controlled trials (RCTs) have not been adequately powered. We report the results of a multicentre RCT of mobile versus fixed bearings. This was part of the knee arthroplasty trial (KAT), where 539 ...
Schalock Robert L - - 2013
Abstract This article focuses on the power of naming, defining, diagnosing, classifying, and planning supports for people with intellectual disability. The article summarizes current thinking regarding these five functions, states the essential question addressed by the respective function, and provides an overview of the high stakes involved for people with ...
Matsuno Tomoya - - 2013
The circannual pupation rhythm of Anthrenus verbasci is entrained to an environmental cycle by changes in photoperiod. Exposure of larvae reared under short-day conditions to long days induced a clear phase delay of the circannual rhythm. There was no notable difference in the initial phase or period of the circannual ...
Lehmann T G - - 2013
The reported prevalence of an asymptomatic slip of the contralateral hip in patients operated on for unilateral slipped capital femoral epiphysis (SCFE) is as high as 40%. Based on a population-based cohort of 2072 healthy adolescents (58% women) we report on radiological and clinical findings suggestive of a possible previous ...
Ebneter Daria S - - 2013
The aim of the current article was to compare stigmatizing attitudes toward eating disorders (EDs), including anorexia nervosa (AN), bulimia nervosa (BN), and binge eating disorder (BED), with stigma toward another weight-related condition (obesity) and a non-weight-related mental disorder (major depressive disorder [MDD]). Participants (N = 447) read five vignettes ...
Nishank Jain - - 2013
A new observational study in Canadian patients shows a U-shaped association between longitudinal change in estimated glomerular filtration rate over a 4-year period and all-cause mortality. This study confirms the findings of previous studies done in middle-aged Taiwanese patients, community-dwelling Medicare beneficiaries, and chronic kidney disease patients. Future studies are ...
Costa Moacir Guilherme da - - 2013
The present systematic review was performed to investigate if there is evidence justifying the prophylactic extraction of third molars, one of the most frequent procedures in oral surgery. A series of searches was carried out for randomized, clinical trials and systematic reviews in seven databases (MEDLINE, BBO, LILACS, Web of ...
Avila Jose - - 2013
Hydroxocobalamin is a treatment for cyanide toxicity with few sideeffects. We report a case of a hemodialysis patient whose treatment was compromised by hydroxocobalamin interference with the blood leak detector.
Oh Jieun - - 2013
Adiponectin (APN) is known as an anti-inflammatory adipokine in obesity and atherosclerosis. Jin et al. examine the effects of APN deficiency in renal ischemia/reperfusion injury (IRI) using APN knockout mice and demonstrate that APN deficiency protects mice from IRI. This newly described role for APN in acute kidney injury opens ...
Lee Franklin - - 2013
The image we present demonstrates the classic hexagonal crystals that are diagnostic of cysteine crystals in a 14-year-old girl with cystinuria. These crystals developed on her stent within a 2-week period after treatment of her stone. The image illustrates the importance of urine microscopy and basic urologic knowledge.
Costa Fontes Karla Bianca Fernandes da - - 2013
Oral cytopathology is a simple, non-invasive technique that could be used for early detection of oral premalignant and malignant lesions, but the effectiveness of this diagnostic approach remains controversial. The aim of this study was to evaluate the sensitivity, specificity, positive and negative predictive values, and accuracy of cytopathology for ...
Dean Grace E - - 2013
An urgent need exists to identify innovative and evidence-based educational methods to help oncology nurses provide safe and high-quality patient care. One promising solution is the dedicated education unit (DEU) educational model, which partners nursing faculty and skilled nursing clinicians to facilitate the clinical experience of undergraduate baccalaureate nursing students. ...
Pichler K - - 2013
Matrix metalloproteinases (MMPs), responsible for extracellular matrix remodelling and angiogenesis, might play a major role in the response of the growth plate to detrimental loads that lead to overuse injuries in young athletes. In order to test this hypothesis, human growth plate chondrocytes were subjected to mechanical forces equal to ...
Kiesswetter E E Institute for Biomedicine of Aging, Friedrich-Alexander Universität Erlangen-Nürnberg, Nürnberg, Germany. - - 2013
The aims of this work were (a) to provide a detailed description of the association between nutritional (Mini Nutritional Assessment; MNA®) and functional status in a sample of older adults receiving home care, using both questionnaire- and performance-based functional methods, and (b) to investigate the impact of different MNA subscales ...
Ong Teng Aik - - 2013
To describe a novel technique for localizing small testicular mass during testicular-sparing surgery (TSS). A 20-year-old man presented with bilateral testicular masses. Both alpha-fetoprotein (AFP) and beta-human chorionic gonadotropin (BHCG) levels were raised. Clinical and imaging studies revealed a 2.7 cm and 0.7 cm mass in the right and left ...
Sanfélix-Gimeno Gabriel G Health Services Research Unit, Center for Public Health Research (CSISP-FISABIO), Valencia, Spain. - - 2013
Pharmacological secondary prevention in patients after an acute coronary syndrome (ACS) has contributed substantially to reductions in cardiovascular morbidity and mortality and, overall, has undergone important improvements in recent years. Nevertheless, there is still a considerable adherence gap and opportunity for improvement. To assess, in a cohort of patients who ...
Iribarren Carlos - - 2013
Mammographically-detected breast arterial calcifications (BAC) are considered to be an incidental finding without clinical importance since they are not associated with increased risk of breast cancer. The goal of this article is to review existing evidence that the presence of BAC on mammography correlates with several (but not all) traditional ...
Koola Maju Mathew MM Maryland Psychiatric Research Center, University of Maryland School of Medicine, Baltimore, USA. - - 2013
We examined the prevalence of childhood (≤ 18 years) physical and sexual abuse reported among patients admitted to the psychiatric inpatient service and the differential rates of this abuse associated with psychiatric diagnoses. This study consisted of a retrospective chart review of 603 patients admitted to a psychiatric ward during ...
Tassé Marc J - - 2013
Abstract The World Health Organization (WHO) is in the process of seeking input from professional stakeholder groups and consumers regarding the draft proposals of the 11th edition of the International Classification of Diseases (ICD-11). The American Association on Intellectual and Developmental Disabilities (AAIDD) convened a small group of distinguished interdisciplinary ...
Pimentel Elizangela Lins Cavalcanti - - 2013
Oral care is frequently suboptimal in children from developing countries, especially those suffering from severe systemic diseases. The aim of the present study was to analyze the oral epidemiological profile of 3-to-5-year-old children with congenital heart disease. Dental and medical records of children evaluated at the Dental Service of the ...
Carr Ellen R - - 2013
One of the most significant world epidemics in history, HIV/AIDS, has been a research priority since its discovery in 1981. This review article provides an update on HIV/AIDS, with a specific focus on the diagnosis and care of patients with HIV- and AIDS-associated cancers.
Iltar S - - 2013
Redisplacement is the most common complication of immobilisation in a cast for the treatment of diaphyseal fractures of the forearm in children. We have previously shown that the three-point index (TPI) can accurately predict redisplacement of fractures of the distal radius. In this prospective study we applied this index to ...
Moore Janice M JM Enterprise Analytics, CVS Caremark, 2211 Sanders Rd., Northbrook, IL 60062, USA. - - 2013
The medication therapy management (MTM) program identified high-risk members in a large employer group and invited them to participate in an MTM program. The intervention consisted of at least 3 consultations with a clinical pharmacist to review and discuss drug therapy. The goal was to improve drug therapy adherence and ...
Firoozmand Leily Macedo - - 2013
The aim of this study was to evaluate the shear bond strength (SBS) of polycrystalline ceramic brackets (PCB) bonded after bleaching treatment using different composite resins and enamel etching times. A total of 144 bovine incisors were randomly divided into two study groups (n = 72, each) as follows: G1, ...
Lisy Karolina - - 2013
Objective: To assess whether histamine type 2 receptor antagonists (H2RAs) improve overall survival when used as pre-, peri-, or postoperative therapy in patients with colorectal cancer who had surgical resection with curative intent.
Wang Chi-Chuan CC National Taiwan University School of Pharmacy, Taipei, Taiwan. - - 2013
Hypertension, hyperlipidemia, and diabetes are among the most prevalent and costly chronic health conditions affecting the U.S. population. Prescription treatments for these conditions are of critical importance to the health of patients, yet suboptimal adherence to prescription treatments for these conditions is not uncommon. While monthly prescription restriction has become ...
Scott C E H - - 2013
The lateral compartment is predominantly affected in approximately 10% of patients with osteoarthritis of the knee. The anatomy, kinematics and loading during movement differ considerably between medial and lateral compartments of the knee. This in the main explains the relative protection of the lateral compartment compared with the medial compartment ...
Gelenberg Alan J - - 2013
The incidence of treatment-emergent sexual dysfunction in the acute and continuation phases of the prevention of recurrent episodes of depression with venlafaxine ER for two years (PREVENT) study was assessed. Adult outpatients with recurrent major depressive disorder were randomly assigned to receive venlafaxine extended release (ER; 75-300 mg/day) or fluoxetine ...
Nitzan Uri - - 2013
The aim of this study was to investigate the opinions of healthy students regarding the acceptability of placebo treatment if they were to experience depression. A survey was conducted among 344 students in five academic centers in Israel. After a thorough explanation of the placebo effect, its efficacy and limitations ...
Olley J Gregory - - 2013
Abstract Definitions and associated descriptions of the condition now commonly known as intellectual disability serve many functions. The Atkins v. Virginia U.S. Supreme Court decision (2002) has called attention to the importance of clear, objective, and measureable wording of the definition. This article discusses the potential for misunderstanding and misinterpretation ...
Novick Kerry Kelly - - 2013
To address the neglect of the importance of parent work in the psychodynamic psychotherapy of children and adolescents, the authors present a model of concurrent dynamic parent work that has demonstrated success with patients of all ages. The model includes dual goals for all therapies, addresses the challenge of confidentiality ...
Vibha Pandey - - 2013
People with mental disorders experience impaired quality of life (QOL). In India, spouses form the most important caregiver for the patient and therefore impact the patients' QOL. However, relatively little is known about marital adjustment, which can definitely influence QOL of patients with mental illness. This study intended to explore ...
Ford Marty - - 2013
Abstract This article discusses the history of the grassroots movement led by self-advocates and their families to replace the stigmatizing term mental retardation with intellectual disability in federal statute. It also describes recent and pending changes in federal regulations and policy to adopt the new terminology for Social Security and ...
Nakase Yuta - - 2013
Xenos is a strepsipteran genus whose members are parasitic to eusocial wasps, including the hornet genus Vespa. We undertook an extensive sampling of strepsipterans in Xenos from hornets collected in East Asia and performed molecular phylogenetic analyses based on mitochondrial cytochrome c oxidase subunit I gene sequences (652 bp) to ...
Mahon Suzanne M - - 2013
Genetic testing for hereditary cancer syndromes is becoming increasingly more common. Once a mutation is detected in a family, other family members can undergo single-site mutation testing to determine if they have inherited the increased risk for developing cancer, with the intent of providing tailored and appropriate cancer prevention and ...
Mlika Mona - - 2013
Malignant pleural mesothelioma (MPM) is a challenging diagnosis characterized by the absence of real specific diagnostic markers. Positivity with the galectin-3 antibody was assessed by a cytoplasmic expression in 17 MPM. Fourteen cases expressed the galectin-3 antibody. The three negative cases consisted of epithelioid, biphasic, and sarcomatoid MPM. The 14 ...
Henry Barbara J - - 2013
Oncology nurses should be aware of smoking-related public health legislation and tobacco use prevention resources as well as increase their knowledge of psycho-education materials, medications, and products available to aid smoking cessation. Smoking is the leading cause of preventable death; one out of five deaths in the United States is ...
Marques Luciene Alves Moreira LA Federal University of Alfenas, Alfenas, MG, Brazil. - - 2013
Several studies have established the effectiveness of pharmaceutical care (PC) in patients with heart failure, diabetes, hypertension, and dyslipidemia. However, there are few studies using standardized methods, e.g., randomized controlled trials, to assess the effectiveness of pharmacotherapy follow-up (PF) in patients with depression. To assess the effectiveness of PC via ...
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